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Merge main into branch #708

Merged
merged 23 commits into from
Feb 11, 2025
Merged

Merge main into branch #708

merged 23 commits into from
Feb 11, 2025

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stefanpeidli
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Lilly-May and others added 23 commits September 20, 2024 18:16
* Fixed DEG layer retrieval

* Use-case tutorial icons

* Restructure tutorial page

* Subgroup tutorials
* Add uncertainty score in KNN label_transfer in PerturbationSpace
Certainty is quantified as the fraction of nearest neighbors belonging to the classified (i.e. the most abundant) label compared to the total number of nearest neighbors.

* Update pre-commit-config.yaml
Replaces yanked dependency of mypy "types-pkg-resources" with "types-setuptools" as recommended: https://pypi.org/project/types-pkg-resources/

* Improve label imputation in PerturbationSpace class
Key changes:
- Now uses KNN graph in adata: saves cost and increases consistency
- Vectorized operations instead of expensive for loop
- Distance weighting for KNN imputation
- Quantifies uncertainty as local KNN label entropy
* Augur scsim warnings

Signed-off-by: zethson <[email protected]>

* Submodules

Signed-off-by: zethson <[email protected]>

---------

Signed-off-by: zethson <[email protected]>
* Augur scsim warnings

Signed-off-by: zethson <[email protected]>

* Submodules

Signed-off-by: zethson <[email protected]>

* Add super draft of pertpy validator

Signed-off-by: zethson <[email protected]>

* Polish

Signed-off-by: zethson <[email protected]>

* Polish

Signed-off-by: zethson <[email protected]>

* Nested try

Signed-off-by: zethson <[email protected]>

* validator in test

Signed-off-by: zethson <[email protected]>

* try uv for rtd

Signed-off-by: zethson <[email protected]>

* rtd uv

Signed-off-by: zethson <[email protected]>

* rtd uv

Signed-off-by: zethson <[email protected]>

* rtd uv fix

Signed-off-by: zethson <[email protected]>

* mb sphinx fix for validator

Signed-off-by: zethson <[email protected]>

* docs

Signed-off-by: zethson <[email protected]>

* remove PerturbationValidator from docs

Signed-off-by: zethson <[email protected]>

* remove PerturbationValidator from docs

Signed-off-by: zethson <[email protected]>

---------

Signed-off-by: zethson <[email protected]>
Signed-off-by: zethson <[email protected]>
* Fix jax random array

Signed-off-by: zethson <[email protected]>

* Fix further jax warnings

Signed-off-by: zethson <[email protected]>

* Fix edger

Signed-off-by: zethson <[email protected]>

* Fix choice

Signed-off-by: zethson <[email protected]>

---------

Signed-off-by: zethson <[email protected]>
* Switch to formulaic-contrasts

* Cleanup

* removing design matrix workaround (#691)

Co-authored-by: Emma Dann <[email protected]>

* Fix PyDESeq2

* Update tests

* fix typo in gitignore

* Remove contrast dataclass, which isnt used anywhere

* Fix edgeR rpy2 tests (#692)

* fix broken rpy2 edger tests

* updated edger tests

* Fix tests (scipy)

Signed-off-by: zethson <[email protected]>

* submodule

Signed-off-by: zethson <[email protected]>

* Remove unused code

Signed-off-by: zethson <[email protected]>

* type hints

Signed-off-by: zethson <[email protected]>

---------

Signed-off-by: zethson <[email protected]>
Co-authored-by: Emma Dann <[email protected]>
Co-authored-by: Emma Dann <[email protected]>
Co-authored-by: zethson <[email protected]>
Signed-off-by: zethson <[email protected]>
Signed-off-by: zethson <[email protected]>
* Fix probability data type

Signed-off-by: Lukas Heumos <[email protected]>

* Optimize mean_var distance

Signed-off-by: Lukas Heumos <[email protected]>

---------

Signed-off-by: Lukas Heumos <[email protected]>
* Try buildjet

Signed-off-by: Lukas Heumos <[email protected]>

* Try buildjet large

Signed-off-by: Lukas Heumos <[email protected]>

* speed up predict_differential_prioritization

Signed-off-by: Lukas Heumos <[email protected]>

* speed up tests

Signed-off-by: Lukas Heumos <[email protected]>

---------

Signed-off-by: Lukas Heumos <[email protected]>
Signed-off-by: Lukas Heumos <[email protected]>
* Removed show parameter

* Adapt plotting API for Augur, Coda, Dialogue

* Adapted plotting API for Milo, Mixscape, scgen

* Add joblib

* Remove joblib

---------

Co-authored-by: Lukas Heumos <[email protected]>
Signed-off-by: Lukas Heumos <[email protected]>
…695)

* Added Mixscape seeds and test

* Added manual reference cell selection method

* Updated docs method descriptions

* Merged main into branch

* Fixed merge conflict

* Merged main

* Added citation to docs

* Renamed 'manual' selection mode to 'split_by'
@stefanpeidli stefanpeidli merged commit 359bb40 into feature/guide_assignment Feb 11, 2025
4 of 6 checks passed
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4 participants