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v4.25 (#1200)
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* v4.25

* Update src/main/webapp/app/config/constants.tsx

Co-authored-by: Calvin Lu <[email protected]>

---------

Co-authored-by: Calvin Lu <[email protected]>
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jfkonecn and calvinlu3 authored Jan 30, 2025
1 parent 200a3da commit 8ec6040
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Showing 5 changed files with 201 additions and 49 deletions.
1 change: 1 addition & 0 deletions src/main/webapp/app/config/constants.tsx
Original file line number Diff line number Diff line change
Expand Up @@ -866,6 +866,7 @@ export type DataRelease = {
};

export const DATA_RELEASES: DataRelease[] = [
{ date: '01302025', version: 'v4.25' },
{ date: '12192024', version: 'v4.24' },
{ date: '11262024', version: 'v4.23' },
{ date: '10242024', version: 'v4.22' },
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1 change: 1 addition & 0 deletions src/main/webapp/app/pages/newsPage/NewsPage.tsx
Original file line number Diff line number Diff line change
Expand Up @@ -86,6 +86,7 @@ export default class NewsPage extends React.Component<{
<CitationText />
</div>
<div className="mt-2">
<NewsList date={'01302025'} />
<NewsList date={'12192024'} />
<NewsList date={'11262024'} />
<NewsList date={'10242024'} />
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138 changes: 138 additions & 0 deletions src/main/webapp/app/pages/newsPage/NewsPageContent.tsx
Original file line number Diff line number Diff line change
Expand Up @@ -301,6 +301,144 @@ const EVIDENCE_COLUMN_SEPARATOR = '; ';
// https://stackoverflow.com/questions/41947168/is-it-possible-to-use-keyof-operator-on-literals-instead-of-interfaces

export const NEWS_BY_DATE: { [date: string]: NewsData } = {
'01302025': {
priorityNews: [
<span>
Happy New Year! As of January 30th, 2025, fifteen Level 1, twelve Level
2, eighteen Level 3 and eleven Level 4 treatments for unique
biomarker-selected indications were added to OncoKB. A table summarizing
these changes can be found here{' '}
<YearEndReviewPageLink year={'2024'}>here</YearEndReviewPageLink>. The
“Precision Oncology: 2024 in Review” article can be found{' '}
<Linkout
link={
'https://aacrjournals.org/cancerdiscovery/article/14/12/2332/750142/Precision-Oncology-2024-in-ReviewPrecision'
}
>
here
</Linkout>
.
</span>,
],
changedAnnotations: [
{
columnHeaderType: AnnotationColumnHeaderType.NEW_ALTERATION_WITH_LEVEL,
content: [
[
'2',
'ERBB2',
'Oncogenic Mutations',
'Cervical Cancer',
'Neratinib',
[
<WithSeparator separator={EVIDENCE_COLUMN_SEPARATOR}>
<span>
Inclusion in Cervical Cancer NCCN Guidelines V1.2025
</span>
<PMIDLink pmids="38211393" />
</WithSeparator>,
],
],
],
},
{
columnHeaderType:
AnnotationColumnHeaderType.PROMOTION_TUMOR_TYPE_SPECIFIC_EVIDENCE,
content: [
[
'KRAS',
'G12C',
'Small Bowel Cancer',
<div>
<div style={{ fontStyle: 'italic' }}>
{DRUGS_PROMOTED_IN_ONCOKB}:
</div>
<div>Adagrasib (Level 2, previously Level 3A)</div>
<br></br>
<div style={{ fontStyle: 'italic' }}>
{DRUGS_ADDED_TO_ONCOKB}:
</div>
<div>Sotorasib (Level 2)</div>
</div>,
'3A',
'2',
<WithSeparator separator={EVIDENCE_COLUMN_SEPARATOR}>
<span>
Inclusion in Small Bowel Adenocarcinoma NCCN Guidelines V1.2025
</span>
<PMIDLink pmids="32955176, 37099736, 36546659, 34919824" />
</WithSeparator>,
],
],
},
{
columnHeaderType: AnnotationColumnHeaderType.UPDATED_SAME_LEVEL_DRUG,
content: [
[
'1',
'ALK',
<WithSeparator separator={', '}>
<AlterationPageLink hugoSymbol="ALK" alteration="Fusions">
Fusions
</AlterationPageLink>
</WithSeparator>,
'Non-Small Cell Lung Cancer',
<div>
<div>
Alectinib, Brigatinib, Certinib, Crizotinib, Lorlatinib (Level
1)
</div>
<br />
<div>NVL-655 (Level 3A)</div>
</div>,
'Ensartinib (Level 1)',
<WithSeparator separator={EVIDENCE_COLUMN_SEPARATOR}>
<FdaApprovalLink
approval="ensartinib"
link="https://www.fda.gov/drugs/resources-information-approved-drugs/fda-approves-ensartinib-alk-positive-locally-advanced-or-metastatic-non-small-cell-lung-cancer"
/>
<PMIDLink pmids="34473194" />
</WithSeparator>,
],
[
'1',
'KRAS',
<WithSeparator separator={', '}>
<AlterationPageLink hugoSymbol="KRAS" alteration="G12C">
G12C
</AlterationPageLink>
</WithSeparator>,
'Colorectal Cancer',
<div>
<div style={{ textDecoration: 'underline' }}>Sensitivity</div>
<div>Adagrasib + Cetuximab (Level 1)</div>
<br />
<div>
Adagrasib + Panitumumab, Sotorasib + Cetuximab, Sotorasib +
Panitumumab (Level 2)
</div>
<br />
<div>Binimetinib, Cobimetinib, Trametinib (Level 4)</div>
<br />
<div style={{ textDecoration: 'underline' }}>Resistance</div>
<div>
Cetuximab, Panitumumab, Tucatinib + Trastuzumab (Level R1)
</div>
</div>,
'Sotorasib + Panitumumab (Level 1)',
<WithSeparator separator={EVIDENCE_COLUMN_SEPARATOR}>
<FdaApprovalLink
approval="sotorasib with panitumumab"
link="https://www.fda.gov/drugs/resources-information-approved-drugs/fda-approves-sotorasib-panitumumab-kras-g12c-mutated-colorectal-cancer"
/>
<PMIDLink pmids="37870968" />
</WithSeparator>,
],
],
},
],
newlyAddedGenes: ['AKT1S1', 'ALOX15B'],
},
'12192024': {
priorityNews: [
<span>
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