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- title: "Algorithms for Genome Sequence Analysis" | ||
term: 2016 Fall | ||
type: course | ||
link: | ||
url: https://jts.github.io/csc2417/ | ||
display: "CSC 2417" | ||
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- title: "Informatics on High-throughput Sequencing Data" | ||
term: 2014-2017 | ||
type: cbw | ||
link: | ||
url: https://bioinformatics.ca/workshops | ||
display: "CBW" | ||
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- title: "Bioinformatics for Cancer Genomics" | ||
term: 2013-2017 | ||
type: cbw | ||
link: | ||
url: https://bioinformatics.ca/workshops | ||
display: "CBW" | ||
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"Epidemic establishment and cryptic transmission of Zika virus in Brazil and the Americas" http://biorxiv.org/content/early/2017/02/02/105171 | ||
"De novo genome and transcriptome assembly of the Canadian beaver (Castor canadensis)" http://www.g3journal.org/content/early/2017/01/13/g3.116.038208.1 | ||
"Multiplex PCR method for MinION and Illumina sequencing of Zika and other virus genomes directly from clinical samples" http://biorxiv.org/content/early/2017/01/09/098913 | ||
"A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns" http://www.nature.com/nature/journal/v538/n7625/full/nature19823.html | ||
"Evaluation of GRCh38 and de novo haploid genome assemblies demonstrates the enduring quality of the reference assembly" http://biorxiv.org/content/early/2016/08/30/072116 | ||
"Using reference-free compressed data structures to analyse sequencing reads from thousands of human genomes" http://genome.cshlp.org/content/27/2/300.abstract | ||
"A global reference for human genetic variation" http://www.nature.com/nature/journal/v526/n7571/full/nature15393.html | ||
"trio-sga: facilitating de novo assembly of highly heterozygous genomes with parent-child trios" http://biorxiv.org/content/early/2016/05/03/051516 | ||
"Detecting DNA Methylation using the Oxford Nanopore Technologies MinION sequencer" http://www.nature.com/nmeth/journal/vaop/ncurrent/full/nmeth.4184.html | ||
"Nanocall: an open source basecaller for Oxford Nanopore sequencing data" https://academic.oup.com/bioinformatics/article/33/1/49/2525680/Nanocall-an-open-source-basecaller-for-Oxford | ||
"Real-time, portable genome sequencing for Ebola surveillance" http://www.nature.com/nature/journal/v530/n7589/full/nature16996.html | ||
"A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing" http://www.nature.com/articles/ncomms10001 | ||
"MinION Analysis and Reference Consortium: Phase 1 data release and analysis" https://f1000research.com/articles/4-1075/v1 | ||
"The khmer software package: enabling efficient nucleotide sequence analysis" https://f1000research.com/articles/4-900/v1 | ||
"A complete bacterial genome assembled de novo using only nanopore sequencing data" http://www.nature.com/nmeth/journal/v12/n8/full/nmeth.3444.html | ||
"The genomic and phenotypic diversity of Schizosaccharomyces pombe" http://www.nature.com/ng/journal/v47/n3/full/ng.3215.html | ||
"The theory and practice of genome sequence assembly" http://www.annualreviews.org/doi/abs/10.1146/annurev-genom-090314-050032?journalCode=genom | ||
"A high-definition view of functional genetic variation from natural yeast genomes" https://academic.oup.com/mbe/article/31/4/872/1103434/A-High-Definition-View-of-Functional-Genetic | ||
"Exploring genome characteristics and sequence quality without a reference" https://academic.oup.com/bioinformatics/article-lookup/doi/10.1093/bioinformatics/btu023 | ||
"Assemblathon 2: evaluating de novo methods of genome assembly in three vertebrate species" https://gigascience.biomedcentral.com/articles/10.1186/2047-217X-2-10 | ||
"Insights into hominid evolution from the gorilla genome sequence" http://www.nature.com/nature/journal/v483/n7388/full/nature10842.html | ||
"Efficient de novo assembly of large genomes using compressed data structures" http://genome.cshlp.org/content/early/2011/12/07/gr.126953.111 | ||
"Assemblathon 1: a competitive assessment of de novo short read assembly methods" http://genome.cshlp.org/content/early/2011/09/16/gr.126599.111.abstract | ||
"Trait variation in yeast is defined by population history" http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1002111 | ||
"Copy number variant detection in inbred strains from short read sequence data" https://academic.oup.com/bioinformatics/article-lookup/doi/10.1093/bioinformatics/btp693 | ||
"Revealing the genetic structure of a trait by sequencing a population under selection" http://genome.cshlp.org/content/21/7/1131.full | ||
"Efficient construction of an assembly string graph using the FM-index" https://academic.oup.com/bioinformatics/article/26/12/i367/286190/Efficient-construction-of-an-assembly-string-graph | ||
"Deep short-read sequencing of chromosome 17 from the mouse strains A/J and CAST/Ei identifies significant germline variation and candidate genes that regulate liver triglyceride levels" https://genomebiology.biomedcentral.com/articles/10.1186/gb-2009-10-10-r112 | ||
"Complex landscapes of somatic rearrangement in human breast cancer genomes" http://www.nature.com/nature/journal/v462/n7276/full/nature08645.html | ||
"ABySS: a parallel assembler for short read sequence data" http://genome.cshlp.org/content/19/6/1117 |
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- title: "Detecting DNA Methylation using the Oxford Nanopore Technologies MinION sequencer" | ||
authors: Jared T Simpson, Rachael Workman, Philip C Zuzarte, Matei David, Lewis Jonathan Dursi, Winston Timp | ||
year: 2017 | ||
preprint: 0 | ||
link: | ||
url: http://www.nature.com/nmeth/journal/vaop/ncurrent/full/nmeth.4184.html | ||
display: "Nature Methods" | ||
|
||
- title: "Epidemic establishment and cryptic transmission of Zika virus in Brazil and the Americas" | ||
authors: Nuno R Faria, Josh Quick, Ingra Morales, Julien Theze, Jacqueline G de Jesus, Marta Giovanetti, Moritz UG Kraemer, Sarah C Hill et al. | ||
year: 2017 | ||
preprint: 1 | ||
link: | ||
url: http://biorxiv.org/content/early/2017/02/02/105171 | ||
display: "bioRxiv" | ||
|
||
- title: "De novo genome and transcriptome assembly of the Canadian beaver (Castor canadensis)" | ||
authors: Si Lok, Tara A Paton, Zhuozhi Wang, Gaganjot Kaur, Susan Walker, Ryan KC Yuen, Wilson WL Sung, Joseph Whitney et al. | ||
year: 2017 | ||
preprint: 0 | ||
link: | ||
url: http://www.g3journal.org/content/early/2017/01/13/g3.116.038208.1 | ||
display: "G3: Genes, Genomes, Genetics" | ||
|
||
- title: "Multiplex PCR method for MinION and Illumina sequencing of Zika and other virus genomes directly from clinical samples" | ||
authors: Joshua Quick, Nathan D Grubaugh, Steven T Pullan, Ingra M Claro, Andrew D Smith, Karthik Gangavarapu, Glenn Oliveira, Refugio Robles-Sikisaka et al. | ||
year: 2017 | ||
preprint: 1 | ||
link: | ||
url: http://biorxiv.org/content/early/2017/01/09/098913 | ||
display: "bioRxiv" | ||
|
||
- title: "A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns" | ||
authors: Faiyaz Notta, Michelle Chan-Seng-Yue, Mathieu Lemire, Yilong Li, Gavin W Wilson, Ashton A Connor, Robert E Denroche, Sheng-Ben Liang et al. | ||
year: 2016 | ||
preprint: 0 | ||
link: | ||
url: http://www.nature.com/nature/journal/v538/n7625/full/nature19823.html | ||
display: "Nature" | ||
|
||
- title: "Evaluation of GRCh38 and de novo haploid genome assemblies demonstrates the enduring quality of the reference assembly" | ||
authors: Valerie A Schneider, Tina Graves Lindsay, Kerstin Howe, Nathan Bouk, Hsiu-Chuan Chen, Paul A Kitts, Terence D Murphy, Kim D Pruitt et al. | ||
year: 2016 | ||
preprint: 1 | ||
link: | ||
url: http://biorxiv.org/content/early/2016/08/30/072116 | ||
display: "bioRxiv" | ||
|
||
- title: "Using reference-free compressed data structures to analyse sequencing reads from thousands of human genomes" | ||
authors: Dirk-Dominic Dolle, Zhicheng Liu, Matthew L Cotten, Jared T Simpson, Zamin Iqbal, Richard Durbin, Shane A McCarthy, Thomas M Keane | ||
year: 2016 | ||
preprint: 0 | ||
link: | ||
url: http://genome.cshlp.org/content/27/2/300.abstract | ||
display: "Genome Research" | ||
|
||
- title: "A global reference for human genetic variation" | ||
authors: 1000 Genomes Project Consortium et al. | ||
year: 2015 | ||
preprint: 0 | ||
link: | ||
url: http://www.nature.com/nature/journal/v526/n7571/full/nature15393.html | ||
display: "Nature" | ||
|
||
- title: "trio-sga: facilitating de novo assembly of highly heterozygous genomes with parent-child trios" | ||
authors: Milan Malinsky, Jared T Simpson, Richard Durbin | ||
year: 2016 | ||
preprint: 1 | ||
link: | ||
url: http://biorxiv.org/content/early/2016/05/03/051516 | ||
display: "bioRxiv" | ||
|
||
- title: "Nanocall: an open source basecaller for Oxford Nanopore sequencing data" | ||
authors: Matei David, Lewis Jonathan Dursi, Delia Yao, Paul C Boutros, Jared T Simpson | ||
year: 2016 | ||
preprint: 0 | ||
link: | ||
url: https://academic.oup.com/bioinformatics/article/33/1/49/2525680/Nanocall-an-open-source-basecaller-for-Oxford | ||
display: "Bioinformatics" | ||
|
||
- title: "Real-time, portable genome sequencing for Ebola surveillance" | ||
authors: Joshua Quick, Nicholas J Loman, Sophie Duraffour, Jared T Simpson, Ettore Severi, Lauren Cowley, Joseph Akoi Bore, Raymond Koundouno et al. | ||
year: 2016 | ||
preprint: 0 | ||
link: | ||
url: http://www.nature.com/nature/journal/v530/n7589/full/nature16996.html | ||
display: "Nature" | ||
|
||
- title: "A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing" | ||
authors: Tyler S Alioto, Ivo Buchhalter, Sophia Derdak, Barbara Hutter, Matthew D Eldridge, Eivind Hovig, Lawrence E Heisler, Timothy A Beck et al. | ||
year: 2015 | ||
preprint: 0 | ||
link: | ||
url: http://www.nature.com/articles/ncomms10001 | ||
display: "Nature communications" | ||
|
||
- title: "MinION Analysis and Reference Consortium: Phase 1 data release and analysis" | ||
authors: Camilla LC Ip, Matthew Loose, John R Tyson, Mariateresa de Cesare, Bonnie L Brown, Miten Jain, Richard M Leggett, David A Eccles et al. | ||
year: 2015 | ||
preprint: 0 | ||
link: | ||
url: https://f1000research.com/articles/4-1075/v1 | ||
display: "F1000Research" | ||
|
||
- title: "The khmer software package: enabling efficient nucleotide sequence analysis" | ||
authors: Michael R Crusoe, Hussien F Alameldin, Sherine Awad, Elmar Boucher, Adam Caldwell, Reed Cartwright, Amanda Charbonneau, Bede Constantinides et al. | ||
year: 2015 | ||
preprint: 0 | ||
link: | ||
url: https://f1000research.com/articles/4-900/v1 | ||
display: "F1000Research" | ||
|
||
- title: "A complete bacterial genome assembled de novo using only nanopore sequencing data" | ||
authors: Nicholas J Loman, Joshua Quick, Jared T Simpson | ||
year: 2015 | ||
preprint: 0 | ||
link: | ||
url: http://www.nature.com/nmeth/journal/v12/n8/full/nmeth.3444.html | ||
display: "Nature methods" | ||
|
||
- title: "The genomic and phenotypic diversity of Schizosaccharomyces pombe" | ||
authors: Daniel C Jeffares, Charalampos Rallis, Adrien Rieux, Doug Speed, Martin P{ř}evorovsk{ỳ}, Tobias Mourier, Francesc X Marsellach, Zamin Iqbal et al. | ||
year: 2015 | ||
preprint: 0 | ||
link: | ||
url: http://www.nature.com/ng/journal/v47/n3/full/ng.3215.html | ||
display: "Nature genetics" | ||
|
||
- title: "The theory and practice of genome sequence assembly" | ||
authors: Jared T Simpson, Mihai Pop | ||
year: 2015 | ||
preprint: 0 | ||
link: | ||
url: http://www.annualreviews.org/doi/abs/10.1146/annurev-genom-090314-050032?journalCode=genom | ||
display: "Annual review of genomics and human genetics" | ||
|
||
- title: "A high-definition view of functional genetic variation from natural yeast genomes" | ||
authors: Anders Bergström, Jared T Simpson, Francisco Salinas, Benjamin Barré, Leopold Parts, Amin Zia, Alex N Nguyen Ba, Alan M Moses et al. | ||
year: 2014 | ||
preprint: 0 | ||
link: | ||
url: https://academic.oup.com/mbe/article/31/4/872/1103434/A-High-Definition-View-of-Functional-Genetic | ||
display: "Molecular biology and evolution" | ||
|
||
- title: "Exploring genome characteristics and sequence quality without a reference" | ||
authors: Jared T Simpson | ||
year: 2014 | ||
preprint: 0 | ||
link: | ||
url: https://academic.oup.com/bioinformatics/article-lookup/doi/10.1093/bioinformatics/btu023 | ||
display: "Bioinformatics" | ||
|
||
- title: "Assemblathon 2: evaluating de novo methods of genome assembly in three vertebrate species" | ||
authors: Keith R Bradnam, Joseph N Fass, Anton Alexandrov, Paul Baranay, Michael Bechner, Inan{ç} Birol, Sébastien Boisvert, Jarrod A Chapman et al. | ||
year: 2013 | ||
preprint: 0 | ||
link: | ||
url: https://gigascience.biomedcentral.com/articles/10.1186/2047-217X-2-10 | ||
display: "GigaScience" | ||
|
||
- title: "Insights into hominid evolution from the gorilla genome sequence" | ||
authors: Aylwyn Scally, Julien Y Dutheil, LaDeana W Hillier, Gregory E Jordan, Ian Goodhead, Javier Herrero, Asger Hobolth, Tuuli Lappalainen et al. | ||
year: 2012 | ||
preprint: 0 | ||
link: | ||
url: http://www.nature.com/nature/journal/v483/n7388/full/nature10842.html | ||
display: "Nature" | ||
|
||
- title: "Efficient de novo assembly of large genomes using compressed data structures" | ||
authors: Jared T Simpson, Richard Durbin | ||
year: 2012 | ||
preprint: 0 | ||
link: | ||
url: http://genome.cshlp.org/content/early/2011/12/07/gr.126953.111 | ||
display: "Genome research" | ||
|
||
- title: "Assemblathon 1: a competitive assessment of de novo short read assembly methods" | ||
authors: Dent Earl, Keith Bradnam, John St John, Aaron Darling, Dawei Lin, Joseph Fass, Hung On Ken Yu, Vince Buffalo et al. | ||
year: 2011 | ||
preprint: 0 | ||
link: | ||
url: http://genome.cshlp.org/content/early/2011/09/16/gr.126599.111.abstract | ||
display: "Genome research" | ||
|
||
- title: "Trait variation in yeast is defined by population history" | ||
authors: Jonas Warringer, Enikö Zörgö, Francisco A Cubillos, Amin Zia, Arne Gjuvsland, Jared T Simpson, Annabelle Forsmark, Richard Durbin et al. | ||
year: 2011 | ||
preprint: 0 | ||
link: | ||
url: http://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1002111 | ||
display: "PLoS Genet" | ||
|
||
- title: "Copy number variant detection in inbred strains from short read sequence data" | ||
authors: Jared T Simpson, Rebecca E McIntyre, David J Adams, Richard Durbin | ||
year: 2010 | ||
preprint: 0 | ||
link: | ||
url: https://academic.oup.com/bioinformatics/article-lookup/doi/10.1093/bioinformatics/btp693 | ||
display: "Bioinformatics" | ||
|
||
- title: "Revealing the genetic structure of a trait by sequencing a population under selection" | ||
authors: Leopold Parts, Francisco A Cubillos, Jonas Warringer, Kanika Jain, Francisco Salinas, Suzannah J Bumpstead, Mikael Molin, Amin Zia et al. | ||
year: 2011 | ||
preprint: 0 | ||
link: | ||
url: http://genome.cshlp.org/content/21/7/1131.full | ||
display: "Genome research" | ||
|
||
- title: "Efficient construction of an assembly string graph using the FM-index" | ||
authors: Jared T Simpson, Richard Durbin | ||
year: 2010 | ||
preprint: 0 | ||
link: | ||
url: https://academic.oup.com/bioinformatics/article/26/12/i367/286190/Efficient-construction-of-an-assembly-string-graph | ||
display: "Bioinformatics" | ||
|
||
- title: "Deep short-read sequencing of chromosome 17 from the mouse strains A/J and CAST/Ei identifies significant germline variation and candidate genes that regulate liver triglyceride levels" | ||
authors: Ian Sudbery, Jim Stalker, Jared T Simpson, Thomas Keane, Alistair G Rust, Matthew E Hurles, Klaudia Walter, Dee Lynch et al. | ||
year: 2009 | ||
preprint: 0 | ||
link: | ||
url: https://genomebiology.biomedcentral.com/articles/10.1186/gb-2009-10-10-r112 | ||
display: "Genome biology" | ||
|
||
- title: "Complex landscapes of somatic rearrangement in human breast cancer genomes" | ||
authors: Philip J Stephens, David J McBride, Meng-Lay Lin, Ignacio Varela, Erin D Pleasance, Jared T Simpson, Lucy A Stebbings, Catherine Leroy et al. | ||
year: 2009 | ||
preprint: 0 | ||
link: | ||
url: http://www.nature.com/nature/journal/v462/n7276/full/nature08645.html | ||
display: "Nature" | ||
|
||
- title: "ABySS: a parallel assembler for short read sequence data" | ||
authors: Jared T Simpson, Kim Wong, Shaun D Jackman, Jacqueline E Schein, Steven JM Jones, Inan{ç} Birol | ||
year: 2009 | ||
preprint: 0 | ||
link: | ||
url: http://genome.cshlp.org/content/19/6/1117 | ||
display: "Genome research" | ||
|
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- name: Jared Simpson | ||
photo: jared.png | ||
info: Principal Investigator, started 2013 | ||
email: [email protected] | ||
github: https://github.com/jts | ||
twitter: https://twitter.com/jaredtsimpson | ||
number_educ: 2 | ||
education1: PhD, University of Cambridge | ||
education2: BSc, University of British Columbia | ||
|
||
- name: Matei David | ||
photo: matei.jpg | ||
info: Research Software Developer, started 2013 | ||
email: [email protected] | ||
github: github.com/mateidavid | ||
twitter: https://twitter.com/mateidvd | ||
number_educ: 2 | ||
education1: PhD, University of Toronto | ||
education2: BSc, University of Toronto | ||
|
||
- name: Heather Gibling | ||
photo: heather.jpg | ||
info: Graduate Student, started 2016 | ||
email: [email protected] | ||
github: github.com/hgibling | ||
twitter: https://twitter.com/hgibling | ||
number_educ: 2 | ||
education1: MBinf, University of Guelph | ||
education2: BSc, University of Calgary | ||
|
||
- name: Paul Tang | ||
photo: paul.jpg | ||
info: Computational Biologist, started 2016 | ||
email: [email protected] | ||
github: paulswtang | ||
twitter: 0 | ||
number_educ: 1 | ||
education1: BSc, McGill University |
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