Releases: flyark/LIVIA
Releases · flyark/LIVIA
LIVIA v0.1.1
What's New in v0.1.1
Per-Residue Intra-chain LIS & pLDDT Charts
- Prediction Analysis: Per-residue intra-chain LIS and pLDDT plots across all models with avg ± SD shading and selected model overlay. Supports multi-chain (3+) with per-chain color coding.
- AFDB Dimer: Dimer vs Monomer comparison — automatically fetches monomer predictions from AlphaFold DB and compares per-residue intra-chain LIS and pLDDT between monomer and dimer contexts. Shows gain/loss shading.
- FlyPredictome & Ortholog Interactome: Per-residue pLDDT charts across all ranks with avg ± SD shading. Progressively updates as rank PDBs are fetched.
FlyPredictome Enhancements
- Gene Pair search tab: Enter two gene names to directly look up their interaction, with UniProt autocomplete, partial protein detection, and multi-result selection table.
- Partner search filter: Text search input in the "Search by Gene" partner table for quickly finding specific genes in large result sets (e.g., 2000+ partners).
Bug Fixes
- Fixed Sequence Viewer not updating when switching models in Prediction Analysis (was showing union of all models instead of selected model).
LIVIA v0.1
Local Interaction VIsualization and Analysis tools for protein structure predictions.
Pages
- Prediction Analysis — General-purpose analysis for AlphaFold2/AF3/ColabFold/Boltz/Chai-1/OpenFold3
- FlyPredictome — Drosophila protein-protein interaction analysis from FlyPredictome
- Ortholog Predictome — Ortholog interaction predictions from FlyPredictome
- AlphaFold DB Dimer — Two-chain complex analysis from AlphaFold Protein Structure Database
- Monomer Subdomain — Single-chain subdomain interaction analysis from AlphaFold Protein Structure Database
Features
- Interaction residue detection (LIR / cLIR)
- iLIS / iLIA / iLISA calculation
- Mol* 3D structure viewer with custom coloring
- ChimeraX and PyMOL script generation with multiple color modes
- Interactive sequence viewer, contact maps, chord diagrams
- Color presets: gradient, solid, high contrast
- Show complete structure toggle
- Gray non-LIR option for highlighting interacting residues
- Multi-prediction folder support with job selector