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1. pola-rs/polars pola-rs/polars Public

   Extremely fast Query Engine for DataFrames, written in Rust

   Rust 38.6k 2.8k

2. apache/arrow apache/arrow Public

   Apache Arrow is the universal columnar format and multi-language toolbox for fast data interchange and in-memory analytics

   C++ 16.8k 4.1k

3. dask/dask dask/dask Public

   Parallel computing with task scheduling

   Python 13.8k 1.9k

4. apache/datafusion apache/datafusion Public

   Apache DataFusion SQL Query Engine

   Rust 8.8k 2.1k

5. biopython/biopython biopython/biopython Public

   Official git repository for Biopython (originally converted from CVS)

   Python 5k 1.9k

6. scverse/scanpy scverse/scanpy Public

   Single-cell analysis in Python. Scales to >100M cells.

   Python 2.5k 743