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@byenzyme

Enzyme Labs

tools for compounding knowledge

🧬 Enzyme Labs

Tools for compounding knowledge.

Your notes, meetings, and conversations should get more valuable as they accumulate — not scatter into a timeline you'll never reread. We build on-device tools that turn a growing knowledge base into structured, queryable context your agents can actually use.

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What we build

🧬 Enzyme — a compile step for knowledge bases. Point it at a markdown corpus or Obsidian vault and it builds a concept graph in under 20 seconds; queries run locally in ~8ms on an on-device model. No runtime reasoning, no conversation history — the expensive work happens once at init.

📝 Margins — vault-native meeting capture. Records meetings from your terminal (no bot joins the call), with a timestamped notepad for the moments that matter. Transcription and diarization run on your machine, and each note is distilled with the memory of the meetings before it.

Ways in

  • enzyme-skill — a self-contained, cross-agent Agent Skill for exploring Obsidian vaults with Enzyme.
  • enzyme-bootstrap — a template Obsidian vault for Claude Code + Enzyme; syncs Gmail and Granola meetings into wikilinked markdown.
  • enzyme-sdk-python — the Python SDK for building on Enzyme (beta).

Install

# Enzyme
brew install byenzyme/enzyme/enzyme-cli

# Margins
brew install byenzyme/margins/margins
Local-first · on-device · your data stays yours — byenzyme.com

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  1. margins margins Public

    Vault-native meeting capture. Timestamped notepad, local transcription, and vault-connected notes.

    Rust 34 3

  2. enzyme enzyme Public

    A compile step for knowledge bases. Gives your agent a concept graph of your content — under 20s to index, 8ms queries on device.

    TypeScript 58 1

  3. enzyme-skill enzyme-skill Public

    Agent Skill for exploring Obsidian vaults with Enzyme — self-contained, cross-agent compatible

    Python 63 3

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