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A whole bunch (all?) of the talks from PyCon 2012 are on line as videos. Here are a few I recommend:
The Art of Subclassing
If your class has only two methods -- and one of them is __init__ -- you don't need a class
Stop Writing Classes
Good talk on Grace Hopper's: It's easier to ask forgiveness than permission -- in Python and other CS topics
Forgiveness or Permission