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// malignant epithelial cells | ||
malignant epithelial cell,oxygen,decreases,necrosis,0,3.75,8,0 | ||
malignant epithelial cell,oxygen,increases,cycle entry,0.003333,21.5,4,0 | ||
malignant epithelial cell,pressure,decreases,cycle entry,0,1,4,0 | ||
malignant epithelial cell,apoptotic,increases,apoptotic debris secretion,0.017,0.1,10,1 | ||
malignant epithelial cell,necrotic,increases,necrotic debris secretion,0.017,0.1,10,1 | ||
malignant epithelial cell,oxygen,decreases,migration speed,0,5,4,0 | ||
malignant epithelial cell,damage,increases,apoptosis,0.1,5,8,0 | ||
// | ||
// M0 macrophages | ||
M0 macrophage,necrotic debris,increases,transform to M1 macrophage,0.05,0.005,4,0 | ||
M0 macrophage,apoptotic debris,decreases,migration speed,0.1,0.005,4,0 | ||
M0 macrophage,necrotic debris,decreases,migration speed,0.1,0.005,4,0 | ||
M0 macrophage,volume,decreases,phagocytose dead cell,0,6000,4,0 | ||
// M1 macrophages | ||
// M1 macrophage,oxygen,decreases,transform to M2 macrophage,0.0,5,8,0 | ||
M1 macrophage,oxygen,decreases,transform to M2 macrophage,0.0001,5,8,0 | ||
M1 macrophage,apoptotic debris,decreases,migration speed,0.1,0.005,4,0 | ||
M1 macrophage,necrotic debris,decreases,migration speed,0.1,0.005,4,0 | ||
M1 macrophage,volume,decreases,phagocytose dead cell,0.0,6000,4,0 | ||
// M2 macrophages | ||
M2 macrophage,apoptotic debris,decreases,migration speed,0.1,0.005,4,0 | ||
M2 macrophage,necrotic debris,decreases,migration speed,0.1,0.005,4,0 | ||
M2 macrophage,volume,decreases,phagocytose dead cell,0.0,6000,4,0 | ||
// effector cells | ||
effector T cell,pro-inflammatory factor,increases,attack malignant epithelial cell,0.01,1,4,0 | ||
effector T cell,contact with malignant epithelial cell,decreases,migration speed,0.01,0.1,10,0 | ||
effector T cell,pro-inflammatory factor,increases,migration speed,1,0.01,4,0 | ||
effector T cell,anti-inflammatory factor,increases,transform to exhausted T cell,0.001,0.5,4,0 | ||
// exhausted cells | ||
exhausted T cell,anti-inflammatory factor,decreases,migration speed,0.001,0.5,4,0 | ||
exhausted T cell,contact with malignant epithelial cell,decreases,migration speed,0.01,0.1,10,0 | ||
// comment line | ||
// | ||
// 0 1 2 3 4 5 6 7 | ||
// Cell type, signal, direction, behavior, max response value, half-max, Hill power, applies to dead? | ||
tumor cell,damage,increases,apoptosis,9e9,30,100,0 |
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