This is the release of the Rhesus Immune Reference Atlas (RIRA), as published in Cell Genomics. RIRA is a multi-tissue single-cell RNA-seq atlas from Rhesus macaque cells, including data from 7 tissues and 47 animals. It provides highly annotated reference data, and a number of pipelines to assign cell type to your data using RIRA's built-in models and/or gene modules.