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<!DOCTYPE html>
<html lang="en">
<head>
<title>Xiaoru Dong — </title>
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<h2 class="mt-3">Xiaoru Dong</h2>
<p> Ph.D. Biostatistics</p>
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<h2 class="introduction-heading mb-4">Software</h2>
<!-- Space for the figure -->
<h5>GitHub Software Packages</h5>
<p><strong>simCRISPR:</strong> An R package for simulating pooled CRISPR screening data under various experimental designs to support method development and benchmarking in CRISPR analysis. <a href="https://github.com/xiaorudong/simCRISPR">Available at: GitHub</a>.</p>
<p><strong>Escort:</strong> Methodology and an R package implementing Escort. This method evaluates a single-cell RNA-seq dataset’s suitability for trajectory inference and for quantifying trajectory properties influenced by analysis decisions. <a href="https://github.com/xiaorudong/Escort">Available at: GitHub</a>.</p>
<p><strong>berm:</strong> Bootstrap-Enhanced Regularization Method. This package implements the Bootstrap-Enhanced Regularization Method (BERM), a statistical approach aiming to enhance the robustness and accuracy of variable selection and coefficient estimation in immunophenotyping datasets. <a href="https://github.com/xiaorudong/berm">Available at: GitHub</a>.</p>
<h5>Interactive Tools and Applications</h5>
<p><strong>shinyEscort:</strong> An interactive Shiny application for guiding trajectory construction in single-cell RNA-seq data. <a href="https://rbacher.rc.ufl.edu/escort/index.html">Available at: shinyEscort website</a>.</p>
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