gaming-talon.yml

unique-id: gaming-talon
phe-label: V-22DEC-01
who-label: Omicron
belongs-to-lineage:
- PANGO: CH.1.1
description: This variant is a sub-lineage of BA.2.75 (Omicron)
information-sources:
- https://github.com/cov-lineages/pango-designation/issues/1113
requires: pampered-imagining
variants:
- amino-acid-change: Q380K
  codon-change: CAA-AAA
  gene: ORF1ab
  one-based-reference-position: 3857
  predicted-effect: non-synonymous
  protein: nsp3
  protein-codon-position: 380
  reference-base: C
  type: SNP
  variant-base: A
- amino-acid-change: V182I
  codon-change: GTA-ATA
  gene: ORF1ab
  one-based-reference-position: 18583
  predicted-effect: non-synonymous
  protein: nsp14
  protein-codon-position: 182
  reference-base: G
  type: SNP
  variant-base: A
- amino-acid-change: Q28R
  codon-change: CAA-CGA
  gene: ORF1ab
  one-based-reference-position: 20741
  predicted-effect: non-synonymous
  protein: nsp16
  protein-codon-position: 28
  reference-base: A
  type: SNP
  variant-base: G
- amino-acid-change: K444T
  codon-change: AAG-ACG
  gene: S
  one-based-reference-position: 22893
  predicted-effect: non-synonymous
  protein: surface glycoprotein
  protein-codon-position: 444
  reference-base: A
  type: SNP
  variant-base: C
- amino-acid-change: L452R
  codon-change: CTG-CGG
  gene: S
  one-based-reference-position: 22917
  predicted-effect: non-synonymous
  protein: surface glycoprotein
  protein-codon-position: 452
  reference-base: T
  type: SNP
  variant-base: G
calling-definition:
  confirmed:
    mutations-required: 4
    indels-required: 0
    allowed-wildtype: 0
  probable:
    mutations-required: 3
    indels-required: 0
    allowed-wildtype: 1
  low-qc:
    mutations-required: 0
    indels-required: 0
    allowed-wildtype: 1