diff --git a/compiler-rt/lib/builtins/CMakeLists.txt b/compiler-rt/lib/builtins/CMakeLists.txt
index 49e463e97f9ac..df5455bc6e560 100644
--- a/compiler-rt/lib/builtins/CMakeLists.txt
+++ b/compiler-rt/lib/builtins/CMakeLists.txt
@@ -848,13 +848,18 @@ else ()
     if (CAN_TARGET_${arch})
       cmake_push_check_state()
       # TODO: we should probably make most of the checks in builtin-config depend on the target flags.
-      message(STATUS "Performing additional configure checks with target flags: ${TARGET_${arch}_CFLAGS}")
       set(BUILTIN_CFLAGS_${arch} ${BUILTIN_CFLAGS})
-      list(APPEND CMAKE_REQUIRED_FLAGS ${TARGET_${arch}_CFLAGS} ${BUILTIN_CFLAGS_${arch}})
+      # CMAKE_REQUIRED_FLAGS must be a space separated string
+      # Join BUILTIN_CFLAGS_${arch} and TARGET_${arch}_CFLAGS as a
+      # space-separated string.
+      list(APPEND CMAKE_REQUIRED_FLAGS
+        ${BUILTIN_CFLAGS_${arch}}
+        ${TARGET_${arch}_CFLAGS})
+      list(JOIN CMAKE_REQUIRED_FLAGS " " CMAKE_REQUIRED_FLAGS)
+      message(STATUS "Performing additional configure checks with target flags: ${CMAKE_REQUIRED_FLAGS}")
       # For ARM archs, exclude any VFP builtins if VFP is not supported
       if (${arch} MATCHES "^(arm|armhf|armv7|armv7s|armv7k|armv7m|armv7em|armv8m.main|armv8.1m.main)$")
-        string(REPLACE ";" " " _TARGET_${arch}_CFLAGS "${TARGET_${arch}_CFLAGS}")
-        check_compile_definition(__ARM_FP "${CMAKE_C_FLAGS} ${_TARGET_${arch}_CFLAGS}" COMPILER_RT_HAS_${arch}_VFP)
+        check_compile_definition(__ARM_FP "${CMAKE_C_FLAGS}" COMPILER_RT_HAS_${arch}_VFP)
         if(NOT COMPILER_RT_HAS_${arch}_VFP)
           list(REMOVE_ITEM ${arch}_SOURCES ${arm_Thumb1_VFPv2_DP_SOURCES} ${arm_Thumb1_VFPv2_SP_SOURCES} ${arm_Thumb1_SjLj_EH_SOURCES})
         else()