Change config without restarting server

[DevilLord41]

Hi
what is the way to change config and proxyauth without restarting the server?
I have socks5 connected as upstream, i been removed the user from proxyauth and change the cfg file to remove the user.
eg: i have server start with this:

flush
auth strong 
allow darius1
socks -p4444 -eip1

flush
auth strong 
allow darius2
socks -p4445 -eip2
flush

then i commented this part

auth strong 
allow darius2
socks -p4445 -eip2
flush

when i restart the server, it seems worked but it didnt disconnect the existed socks5 upstream that already connected before the config changed