diff --git a/.changeset/ripe-baths-rush.md b/.changeset/ripe-baths-rush.md
new file mode 100644
index 00000000000..b4274f32094
--- /dev/null
+++ b/.changeset/ripe-baths-rush.md
@@ -0,0 +1,5 @@
+---
+'@primer/react': patch
+---
+
+Only shows the aria-describedby id for loading when the component is in the loading state
diff --git a/packages/react/src/Button/ButtonBase.tsx b/packages/react/src/Button/ButtonBase.tsx
index ba376b52eae..d2ae5a0b6ba 100644
--- a/packages/react/src/Button/ButtonBase.tsx
+++ b/packages/react/src/Button/ButtonBase.tsx
@@ -56,6 +56,9 @@ const ButtonBase = forwardRef(({children, as: Component = 'button', ...props}, f
   const uuid = useId(id)
   const loadingAnnouncementID = `${uuid}-loading-announcement`
 
+  // Only include the loading aria-describedby if there is a loading state
+  const ariaDescribedByIds = loading ? [loadingAnnouncementID, ariaDescribedBy] : [ariaDescribedBy]
+
   if (__DEV__) {
     /**
      * The Linter yells because it thinks this conditionally calls an effect,
@@ -100,9 +103,7 @@ const ButtonBase = forwardRef(({children, as: Component = 'button', ...props}, f
         data-variant={variant}
         data-label-wrap={labelWrap}
         data-has-count={count !== undefined ? true : undefined}
-        aria-describedby={[loadingAnnouncementID, ariaDescribedBy]
-          .filter(descriptionID => Boolean(descriptionID))
-          .join(' ')}
+        aria-describedby={ariaDescribedByIds.filter(descriptionID => Boolean(descriptionID)).join(' ') || undefined}
         // aria-labelledby is needed because the accessible name becomes unset when the button is in a loading state.
         // We only set it when the button is in a loading state because it will supersede the aria-label when the screen
         // reader announces the button name.
diff --git a/packages/react/src/Button/__tests__/Button.test.tsx b/packages/react/src/Button/__tests__/Button.test.tsx
index 5251ed5491d..4f42fbb1b15 100644
--- a/packages/react/src/Button/__tests__/Button.test.tsx
+++ b/packages/react/src/Button/__tests__/Button.test.tsx
@@ -170,6 +170,8 @@ describe('Button', () => {
     )
     const buttonNode = container.getByRole('button')
 
+    fireEvent.click(buttonNode)
+
     expect(buttonNode.getAttribute('aria-describedby')).toBe(`${buttonId}-loading-announcement`)
 
     fireEvent.click(buttonNode)
@@ -192,6 +194,8 @@ describe('Button', () => {
     )
     const buttonNode = container.getByRole('button')
 
+    fireEvent.click(buttonNode)
+
     expect(buttonNode.getAttribute('aria-describedby')).toBe(`${buttonId}-loading-announcement`)
 
     fireEvent.click(buttonNode)
@@ -213,6 +217,10 @@ describe('Button', () => {
         <span>content</span>
       </StatefulLoadingButton>,
     )
+    const buttonNode = container.getByRole('button')
+
+    fireEvent.click(buttonNode)
+
     const buttonDescribedBy = container.getByRole('button').getAttribute('aria-describedby')
     const loadingAnnouncementId = `${buttonId}-loading-announcement`
 
diff --git a/packages/react/src/Button/__tests__/__snapshots__/Button.test.tsx.snap b/packages/react/src/Button/__tests__/__snapshots__/Button.test.tsx.snap
index 0ddfa63424b..0e24734daa4 100644
--- a/packages/react/src/Button/__tests__/__snapshots__/Button.test.tsx.snap
+++ b/packages/react/src/Button/__tests__/__snapshots__/Button.test.tsx.snap
@@ -2,7 +2,6 @@
 
 exports[`Button > respects block prop 1`] = `
 <button
-  aria-describedby="test-button-loading-announcement"
   class="prc-Button-ButtonBase-Eb8-K"
   data-block="block"
   data-loading="false"
@@ -29,7 +28,6 @@ exports[`Button > respects block prop 1`] = `
 
 exports[`Button > respects the alignContent prop 1`] = `
 <button
-  aria-describedby="test-button-loading-announcement"
   class="prc-Button-ButtonBase-Eb8-K"
   data-loading="false"
   data-no-visuals="true"
@@ -55,7 +53,6 @@ exports[`Button > respects the alignContent prop 1`] = `
 
 exports[`Button > respects the large size prop 1`] = `
 <button
-  aria-describedby="test-button-loading-announcement"
   class="prc-Button-ButtonBase-Eb8-K"
   data-loading="false"
   data-no-visuals="true"
@@ -81,7 +78,6 @@ exports[`Button > respects the large size prop 1`] = `
 
 exports[`Button > respects the small size prop 1`] = `
 <button
-  aria-describedby="test-button-loading-announcement"
   class="prc-Button-ButtonBase-Eb8-K"
   data-loading="false"
   data-no-visuals="true"
@@ -107,7 +103,6 @@ exports[`Button > respects the small size prop 1`] = `
 
 exports[`Button > styles danger button appropriately 1`] = `
 <button
-  aria-describedby="test-button-loading-announcement"
   class="prc-Button-ButtonBase-Eb8-K"
   data-loading="false"
   data-no-visuals="true"
@@ -133,7 +128,6 @@ exports[`Button > styles danger button appropriately 1`] = `
 
 exports[`Button > styles invisible button appropriately 1`] = `
 <button
-  aria-describedby="test-button-loading-announcement"
   class="prc-Button-ButtonBase-Eb8-K"
   data-loading="false"
   data-no-visuals="true"
@@ -159,7 +153,6 @@ exports[`Button > styles invisible button appropriately 1`] = `
 
 exports[`Button > styles primary button appropriately 1`] = `
 <button
-  aria-describedby="test-button-loading-announcement"
   class="prc-Button-ButtonBase-Eb8-K"
   data-loading="false"
   data-no-visuals="true"