From 0818c847ccf0910ec9aaa537ff6c66e4a3a22ff2 Mon Sep 17 00:00:00 2001 From: Nico Matentzoglu Date: Thu, 2 Jun 2022 21:24:23 +0300 Subject: [PATCH] Adding Go PLUS (experiment) lots of floating chebi references --- src/ontology/Makefile | 6 +- src/ontology/imports/go_import.owl | 214262 ++++++++++++++++++++++++-- src/ontology/uberon-odk.yaml | 1 + 3 files changed, 199772 insertions(+), 14497 deletions(-) diff --git a/src/ontology/Makefile b/src/ontology/Makefile index bc9ae7c16f..ac58fac4a5 100644 --- a/src/ontology/Makefile +++ b/src/ontology/Makefile @@ -170,10 +170,10 @@ endif # ---------------------------------------- $(REPORTDIR)/$(SRC)-obo-report.tsv: $(SRCMERGED) | $(REPORTDIR) - $(ROBOT) report -i $< $(REPORT_LABEL) $(REPORT_PROFILE_OPTS) --fail-on $(REPORT_FAIL_ON) --print 5 -o $@ + $(ROBOT) report -i $< $(REPORT_LABEL) $(REPORT_PROFILE_OPTS) --fail-on $(REPORT_FAIL_ON) --print 5 -o $@ $(REPORTDIR)/%-obo-report.tsv: % | $(REPORTDIR) - $(ROBOT) report -i $< $(REPORT_LABEL) $(REPORT_PROFILE_OPTS) --fail-on $(REPORT_FAIL_ON) --print 5 -o $@ + $(ROBOT) report -i $< $(REPORT_LABEL) $(REPORT_PROFILE_OPTS) --fail-on $(REPORT_FAIL_ON) --print 5 -o $@ # ---------------------------------------- # Release assets @@ -367,7 +367,7 @@ mirror-cl: | $(TMPDIR) .PHONY: mirror-go .PRECIOUS: $(MIRRORDIR)/go.owl mirror-go: | $(TMPDIR) - if [ $(MIR) = true ] && [ $(IMP) = true ]; then curl -L $(URIBASE)/go.owl --create-dirs -o $(MIRRORDIR)/go.owl --retry 4 --max-time 200 && $(ROBOT) convert -i $(MIRRORDIR)/go.owl -o $@.tmp.owl && mv $@.tmp.owl $(TMPDIR)/$@.owl; fi + if [ $(MIR) = true ] && [ $(IMP) = true ]; then curl -L $(URIBASE)/go/go-base.owl --create-dirs -o $(MIRRORDIR)/go.owl --retry 4 --max-time 200 && $(ROBOT) convert -i $(MIRRORDIR)/go.owl -o $@.tmp.owl && mv $@.tmp.owl $(TMPDIR)/$@.owl; fi ## ONTOLOGY: envo diff --git a/src/ontology/imports/go_import.owl b/src/ontology/imports/go_import.owl index 59e94886c2..d8a19658ed 100644 --- a/src/ontology/imports/go_import.owl +++ b/src/ontology/imports/go_import.owl @@ -1,14 +1,21 @@ - + + + 2022-06-02 @@ -24,26813 +31,212080 @@ - + - + + definition + - + - + - + + - + - - - BFO:0000050 - part_of - part of - + - + - - - BFO:0000051 - has_part - has part - + + term replaced by + - + - - - RO:0002211 - regulates - regulates - + - + - - - RO:0002212 - negatively_regulates - negatively regulates - + + + - + - - - RO:0002213 - positively_regulates - positively regulates - + + + - + + + + - + - - - reproduction - + + + - + - - - - - polysaccharide biosynthetic process - + + + - + - - - - - polysaccharide catabolic process - + + + - + - - - nuclear division - + + + - + - - - - - - - - - - - - - - - - - - - - regulation of glutamine family amino acid metabolic process - + + + - + - - - response to acid chemical - + + + - + - - - skeletal system development - + + + - + - - - ossification - + + + - + - - - - - - - - - angiogenesis - + + + - + - - - cilium or flagellum-dependent cell motility - + + + - + - - - - - - - - - luteinization - + + + - + - - - - - - - - - - - - - - - - - - - - - regulation of cell growth - + + + - + - - - - - - - - - blood vessel development - + + + - + - - - - - - - - - - - - - - - - - - - - branching involved in blood vessel morphogenesis - + + + - + - - - temperature homeostasis - + - + - - - - response to hypoxia - + - + - - - ameboidal-type cell migration - + - + - - - female germ cell nucleus - + + subset_property + - + - - - - - histamine metabolic process - + + synonym_type_property + - + - - - - gastric acid secretion - + + consider + - + - - - in utero embryonic development - + - + - - - - - - - - - formation of primary germ layer - + - + - - - - - - - - - ectoderm formation - + - + - - - - - - - - - endoderm formation - + + has_alternative_id + - + - - - - - - - - - mesoderm formation - + + has_broad_synonym + - + - - - - - - - - - photoreceptor outer segment - + + database_cross_reference + - + - - - - morphogenesis of a branching structure - + + has_exact_synonym + - + - - - cell activation - + + has_narrow_synonym + - + - - - - serotonin secretion - + + has_obo_format_version + - + - - - - - - - - - embryonic epithelial tube formation - + + has_obo_namespace + - + - - - - - - - - - neural tube formation - + + has_related_synonym + - + - - - - - - - - - neural tube closure - + + has_scope + - + - - - photoreceptor inner segment - + + has_synonym_type + - + - - - - - - - - - vasculature development - + - + - - - intramembranous ossification - + + in_subset + - + - - - - - - - - - endochondral ossification - + - + - - - - - - - - - - - - - - - - - - - - nervous system process involved in regulation of systemic arterial blood pressure - + - + - - - - - - - - - renal system process involved in regulation of blood volume - + + shorthand + - + - - - - - - - - - regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback - + - + - - - regulation of systemic arterial blood pressure by chemoreceptor signaling - + - + - - - - regulation of systemic arterial blood pressure by hormone - + - + - - - regulation of systemic arterial blood pressure by vasopressin - + - + - - - - - - - - - - - - - - - - - - - - - detection of hypoxic conditions in blood by chemoreceptor signaling - + - + - - - - - - - - - morphogenesis of an epithelium - - + - - - regulation of blood volume by renin-angiotensin - + + + + BFO:0000050 + external + part_of + part_of + part of + - + - - - - - - - - - - - - - - - - - - - - - - - - - renin-angiotensin regulation of aldosterone production - - + + + BFO:0000051 + external + has_part + has_part + has part + + - + - - - - regulation of heart rate - + + BFO:0000062 + external + preceded_by + preceded_by + preceded by + - + - - - - - - - - - - - - - - - - - - - - - positive regulation of mesenchymal cell proliferation - + + BFO:0000063 + external + precedes + precedes + precedes + - + - - - - - - - - - chondrocyte differentiation - + + + + + + BFO:0000066 + external + occurs_in + occurs_in + occurs in + - + - - - - - - - - - chondrocyte development - + + GOREL:0002003 + external + results_in_distribution_of + results_in_distribution_of + results_in_distribution_of + - + - - - - - - - - - - - - - - - regulation of respiratory gaseous exchange by nervous system process - + + + GOREL:0002004 + external + results_in_fission_of + results_in_fission_of + results_in_fission_of + - + - - - amphibian larval development - + + RO:0000053 + external + bearer_of + bearer_of + bearer of + - + - - - nematode larval development - + + RO:0000056 + external + participates_in + participates_in + participates_in + - + - - - - larval development - + + RO:0000057 + external + has_participant + has_participant + has participant + - + - - - - instar larval or pupal development - + + RO:0002007 + external + bounding_layer_of + bounding_layer_of + bounding layer of + - + - - - - instar larval development - + + RO:0002087 + external + immediately_preceded_by + immediately_preceded_by + immediately_preceded_by + - + - - - - - - - - - - - - - - - - - - - - wound healing involved in inflammatory response - + + RO:0002131 + external + overlaps + overlaps + overlaps + - + - - - organ or tissue specific immune response - + - + - - - immune effector process - + - + - - - - - - - - - - - - - - - - - - - - - cell activation involved in immune response - + + RO:0002180 + external + has_component + has_component + has component + - + - - - - - - - - - - - - - - - - - - - - leukocyte activation involved in inflammatory response - + + + RO:0002211 + external + regulates + regulates + regulates + - + - - - - - - - - - - - - - - - lymphocyte activation involved in immune response - + + + RO:0002212 + external + negatively_regulates + negatively_regulates + negatively regulates + - + - - - - - - - - - - - - - - - T cell activation involved in immune response - + + + + + + + RO:0002213 + external + positively_regulates + positively_regulates + positively regulates + - + - - - - - - - - - - - - - - - T cell differentiation involved in immune response - + + RO:0002215 + external + capable_of + capable_of + capable of + - + - - - - - - - - - - - - - - - B cell activation involved in immune response - + + RO:0002216 + external + capable_of_part_of + capable_of_part_of + capable of part of + - + - - - - - - - - - - - - - - - mature B cell differentiation involved in immune response - + + RO:0002220 + external + adjacent_to + adjacent_to + adjacent to + - + - - - plasma cell differentiation - + + RO:0002224 + external + starts_with + starts_with + starts with + - + - - - - memory B cell differentiation - + + RO:0002230 + external + ends_with + ends_with + ends with + - + - - - - - - - - - - - - - - - B cell proliferation involved in immune response - + + RO:0002233 + external + has_input + has_input + has input + - + - - - mature B cell differentiation - + + RO:0002234 + external + has_output + has_output + has output + - + - - - serotonin production involved in inflammatory response - + + RO:0002295 + external + results_in_developmental_progression_of + results_in_developmental_progression_of + results in developmental progression of + - + - - - - - - - - - - - - - - - leukocyte activation involved in immune response - + + RO:0002296 + external + results_in_development_of + results_in_development_of + results in development of + - + - - - immune system process - + + RO:0002297 + external + results_in_formation_of + results_in_formation_of + results in formation of + - + - - - immunoglobulin production - + + RO:0002298 + external + results_in_morphogenesis_of + results_in_morphogenesis_of + results in morphogenesis of + - + - - - hepatic immune response - + + RO:0002299 + external + results_in_maturation_of + results_in_maturation_of + results in maturation of + - + - - - - production of molecular mediator of immune response - + + RO:0002315 + external + results_in_acquisition_of_features_of + results_in_acquisition_of_features_of + results in acquisition of features of + - + - - - - - - - - - - - - - - - - - - - - serotonin secretion involved in inflammatory response - + + RO:0002332 + external + regulates_levels_of + regulates_levels_of + regulates levels of + - + - - - - immune system development - + + RO:0002338 + external + has_target_start_location + has_target_start_location + has target start location + - + - - - - - - - - - leukocyte differentiation - + + RO:0002339 + external + has_target_end_location + has_target_end_location + has target end location + - + - - - - - - - - - production of molecular mediator involved in inflammatory response - + + RO:0002341 + external + results_in_transport_along + results_in_transport_along + results in transport along + - + - - - - - - - - - - - - - - - - - - - - regulation of immunoglobulin production - + + RO:0002343 + external + results_in_growth_of + results_in_growth_of + results in growth of + - + - - - - - - - - - - - - - - - - - - - - - negative regulation of immunoglobulin production - + + RO:0002344 + external + results_in_transport_to_from_or_in + results_in_transport_to_from_or_in + results in transport to from or in + - + - - - - - - - - - - - - - - - - - - - - - positive regulation of immunoglobulin production - + + RO:0002353 + external + output_of + output_of + output of + - + - - - - - - - - - - - - - - - - - - - - regulation of immune system process - + - + - - - - - - - - - - - - - - - - - - - - - negative regulation of immune system process - + + RO:0002565 + external + results_in_movement_of + results_in_movement_of + results in movement of + - + - - - - - - - - - - - - - - - - - - - - - positive regulation of immune system process - + + RO:0002588 + external + results_in_assembly_of + results_in_assembly_of + results_in_assembly_of + - + - - - - - - - - - - - - - - - - - - - - - regulation of leukocyte activation - + + + RO:0002592 + external + results_in_organization_of + results_in_organization_of + results in organization of + - + - - - - - - - - - - - - - - - - - - - - - - negative regulation of leukocyte activation - + + RO:0002608 + external + process_has_causal_agent + process_has_causal_agent + process has causal agent + - + - - - - - - - - - - - - - - - - - - - - - - positive regulation of leukocyte activation - + + RO:0003000 + external + produces + produces + produces + - + - - - - - - - - - - - - - - - - - - - - regulation of immune effector process - + + RO:0003001 + external + produced_by + produced_by + produced by + - + - - - - - - - - - - - - - - - - - - - - - negative regulation of immune effector process - + + RO:0004007 + external + has_primary_input_or_output + has_primary_input_or_output + has primary input or output + - + - - - - - - - - - - - - - - - - - - - - - positive regulation of immune effector process - + + RO:0004008 + external + has_primary_output + has_primary_output + has primary output + - + - - - - - - - - - - - - - - - - - - - - - regulation of production of molecular mediator of immune response - + + RO:0004009 + external + has_primary_input + has_primary_input + has primary input + - + - - - - - - - - - - - - - - - - - - - - - - negative regulation of production of molecular mediator of immune response - + + + RO:0012003 + external + acts_on_population_of + acts_on_population_of + acts on population of + - + - - - - - - - - - - - - - - - - - - - - - - positive regulation of production of molecular mediator of immune response - + + + RO:0012008 + external + results_in_fusion_of + results_in_fusion_of + results in fusion of + - + - - - - peptide secretion - + + + RO:0019000 + gene_ontology + regulates_characteristic + regulates_characteristic + regulates characteristic + - + - - - - - - - - - - - - - - - - - - - - - regulation of peptide secretion - - + - - - - - - - - - - - - - - - - - - - - - negative regulation of peptide secretion - + - + - - - - - - - - - - - - - - - - - - - - - positive regulation of peptide secretion - + - + - - - - - - - - - - - - - - - developmental process involved in reproduction - + - + - - - system process - + - + - - - muscle system process - + - + - - - circulatory system process - + - + - - - renal system process - + - + - - - heart process - + - + - - - - - - - - - respiratory system process - + - + - - - lymph circulation - + - + - - - - - - - - - central nervous system control of baroreceptor feedback - + - + - - - - - - - - - detection of reduced oxygen by chemoreceptor signaling - + - + - - - detection of pH by chemoreceptor signaling - + - + - - - regulation of systemic arterial blood pressure by baroreceptor feedback - + - + - - - regulation of systemic arterial blood pressure by carotid body chemoreceptor signaling - + - + - - - - - - - - - detection of hypoxic conditions in blood by carotid body chemoreceptor signaling - + - + - - - detection of hydrogen ion - + - + - - - - detection of oxygen - + - + - - - - - - - - - detection of reduced oxygen by carotid body chemoreceptor signaling - + - + - - - regulation of systemic arterial blood pressure mediated by a chemical signal - + - + - - - - - - - - - - - - - - - - - - - - renal system process involved in regulation of systemic arterial blood pressure - + - + - - - regulation of systemic arterial blood pressure - + - + - - - regulation of systemic arterial blood pressure by renin-angiotensin - + - + - - - - renal water homeostasis - + - + - - - - - - - - - - - - - - - - - - - - - regulation of glomerular filtration - + - + - - - glomerular filtration - + - + - - - - - - - - - - renal water transport - + - + - - - - - - - - - - - - - - - - - - - - - positive regulation of glomerular filtration + + - + - - - - - - - - - - - - - - - - - - - - - negative regulation of glomerular filtration - + - + - - - - - - - - - - - - - - - - - - - - - regulation of extracellular matrix constituent secretion - + - + - - - - - - - - - - - - - - - - - - - - - - positive regulation of extracellular matrix constituent secretion - + - + - - - - - - - - - - - - - - - - - - - - - - negative regulation of extracellular matrix constituent secretion - + - + - - - cilium movement - + - + - - - - - - - - - - - - - - - - - - - - regulation of cilium movement - + - + - - - - - - - - - - - - - - - - - - - - - positive regulation of cilium movement - + - + - - - - - - - - - - - - - - - - - - - - - negative regulation of cilium movement - + - + - - - - - - - - - - - - - - - - - - - - chondrocyte differentiation involved in endochondral bone morphogenesis - + - + - - - - - - - - - chondrocyte hypertrophy - + - + - - - - - - - - - - - - - - - - - - - - chondrocyte development involved in endochondral bone morphogenesis - + - + - - molecular_function - + - + - - - transmembrane signaling receptor activity - + - + - - cellular_component - + - + - - - extracellular region - + - + - - - - - - - - - fibrinogen complex - + - + - - - collagen trimer - + - + - - - - - - - - - - - - - - - - - - - - fibrillar collagen trimer - + - + - - - collagen type I trimer - + - + - - - collagen type II trimer - + - + - - - collagen type III trimer - + - + - - - - collagen type IV trimer - + - + - - - basement membrane - + - + - - - - - - - - - extracellular space - + - + - - - intracellular anatomical structure - + - + - - - nucleus - + - + - - - - - - - - - - - - - - - nuclear envelope - + - + - - - - - - - - - cytoplasm - + - + - - - - - - - - - vacuole - + - + - - - cytoskeleton - + - + - - - - - - - - - intermediate filament - + - + - - - - - - - - - actin filament - + - + - - - - - - - - - plasma membrane - + - + - - - - - - - - - microvillus - + - + - - - cell-cell junction - + - + - - - - - - - - - bicellular tight junction - + - + - - - - - - - - - - cilium - + - + - - - - - - - - - - - - - - - - - - - - cell cortex - + - + - - - - carbohydrate metabolic process - + - + - - - - polysaccharide metabolic process - + - + - - - - glycogen metabolic process - + - + - - - - glycogen biosynthetic process - + - + - - - - - - - - - - - - - - - - - - - - - regulation of glycogen biosynthetic process - + - + - - - - - glycogen catabolic process - + - + - - - - - - - - - - - - - - - - - - - - - regulation of glycogen catabolic process + + - + - - - - monosaccharide metabolic process - + - + - - - glucose metabolic process - + - + - - - - - aminoglycan metabolic process - + - + - - - - - - aminoglycan biosynthetic process - + - + - - - - glycosaminoglycan biosynthetic process - + - + - - - - alcohol metabolic process - + - + - - - - cellular glucan metabolic process - + - + - - - - cellular aldehyde metabolic process - + - + - - - - - organic acid metabolic process - + - + - - - generation of precursor metabolites and energy - + - + - - - - - - - - - - - - - - - - - - - - regulation of carbohydrate metabolic process - + - + - - - energy reserve metabolic process - + - + - - - - - cellular amino acid metabolic process - + - + - - - - - - - - - - - - - - - - - - - - - - regulation of cellular amino acid metabolic process - + - + - - - - glutamate metabolic process - + - + - - - - cellular modified amino acid metabolic process - + - + - - - cellular biogenic amine metabolic process - + - + - - - - catecholamine metabolic process - + - + - - - thyroid hormone generation - + - + - - - - lipid metabolic process - + - + - - - - - steroid biosynthetic process - + - + - - - - - - bile acid biosynthetic process - + - + - - - - - C21-steroid hormone biosynthetic process - + - + - - - - glucocorticoid biosynthetic process - + - + - - - - mineralocorticoid biosynthetic process - + - + - - - cellular aromatic compound metabolic process - + - + - - - nitrogen compound metabolic process - + - + - - - transport - + - + - - - ion transport - + - + - - - cation transport - + - + - - - anion transport + + + + - + - - - water transport - + - + - - - - - serotonin transport - + - + - - - - - - - - - lipid transport - + - + - - - regulation of pH - + - + - - - - - - - - - - exocytosis - + - + - - - - - - - - - - vesicle fusion - + - + - - - movement of cell or subcellular component - + - + - - - muscle contraction - + - + - - - - - - - - - - - - - - - - - - - - regulation of muscle contraction - + - + - - - smooth muscle contraction - + - + - - - - - - - - - - - - - - - - - - - - regulation of smooth muscle contraction - + - + - - - striated muscle contraction - + - + - - - - - - - - - - - - - - - - - - - - regulation of striated muscle contraction - + - + - - - response to stress - + - + - - - defense response - + - + - - - inflammatory response - + - + - - - - immune response - + - + - - - organelle organization - + - + - - - microtubule-based process - + - + - - - - microtubule-based movement - + - + - - - cell cycle - + - + - - - - - - - - - - - - - - - - - - - - - - - - - male meiotic nuclear division - + - + - - - - - - - - - - - - - - - - - - - - - - - - - female meiotic nuclear division - + - + - - - cell communication - + - + - - - - cell adhesion - + - + - - - leukocyte cell-cell adhesion - + - + - - - - - - - - - - - - - - - - - - - - - negative regulation of cell adhesion - + - + - - - - - - - - - - - - - - - - - - - - - - signal transduction - + - + - - - - cell-cell signaling - + - + - - - - multicellular organism development - + - + - - - - - - - - - gamete generation - + - + - - - - - - - - - - - germ cell development - + - + - - - - spermatogenesis - + - + - - - - - - - - - spermatid development - + - + - - - female gamete generation - + - + - - - - - - - - - - - insemination - + - + - - - - - - - - - - - - - - - - - - - - - gastrulation - + - + - - - ectoderm development - + - + - - - nervous system development - + - + - - - endoderm development - + - + - - - mesoderm development - + - + - - - sex differentiation - + - + - - - - - - - - - - - - - - - - - - - - - - regulation of juvenile hormone secretion - + - + - - - - female pregnancy - + - + - - - respiratory gaseous exchange by respiratory system - + - + - - - digestion - + - + - - - excretion - + - + - - - - body fluid secretion - + - + - - - - - - - - - - - - - - - lactation - + - + - - - - - - - - - - blood coagulation - + - + - - - hemostasis - + - + - - - sensory perception - + - + - - - visual perception - + - + - - - sensory perception of sound - + - + - - - sensory perception of chemical stimulus - + - + - - - sensory perception of smell - + - + - - - behavior - + - + - - - - learning or memory - + - + - - - learning - + - + - - - memory - + - + - - - - - - - - - - - - - - - - - - - - mating behavior - + - + - - - - - - - - - mating - + - + - - - copulation - + - + - - - - rhythmic behavior - + - + - - - circadian rhythm - + - + - - - grooming behavior - + - + - - - locomotory behavior - + - + - - - feeding behavior - + - + - - - - - - - - - chemosensory behavior - + - + - - - blood circulation - + - + - - - - - - - - - - - - - - - - - - - - regulation of heart contraction - + - + - - - protein localization - + - + - - biological_process - + - + - - - metabolic process - + - + - - - - steroid metabolic process - + - + - - - - - bile acid metabolic process - + - + - - - - C21-steroid hormone metabolic process - + - + - - - glucocorticoid metabolic process - + - + - - - - mineralocorticoid metabolic process - + - + - - - - - - - - - regulation of blood pressure - + - + - - - cell population proliferation - + - + - - - - - - - - - - - - - - - - - - - - - positive regulation of cell population proliferation - + - + - - - - - - - - - - - - - - - - - - - - - negative regulation of cell population proliferation - + - + - - - associative learning - + - + - - - - olfactory learning - + - + - - - - - - - - - - gonad development - + - + - - - - - - - - - taste receptor activity - + - + - - - epidermis development - + - + - - - - - - - - - female gonad development - + - + - - - - lipid biosynthetic process - + - + - - - catabolic process - + - + - - - - macromolecule catabolic process - + - + - - - biosynthetic process - + - + - - - - macromolecule biosynthetic process - + - + - - - glutamine family amino acid metabolic process - + - + - - - - glucan biosynthetic process - + - + - - - - glucan catabolic process - + - + - - - response to temperature stimulus - + - + - - - - - protein secretion - + - + - - - amine metabolic process - + - + - - - response to radiation - + - + - - - - response to water deprivation - + - + - - - - - - response to water - + - + - - - response to light stimulus - + - + - - - - gamma-aminobutyric acid metabolic process - + - + - - - - detection of external stimulus - + - + - - - - detection of abiotic stimulus - + - + - - - - - detection of light stimulus - + - + - - - detection of visible light - + - + - - - - - detection of gravity - + - + - - - - - - - - - detection of chemical stimulus - + - + - - - response to external stimulus - + - + - - - response to wounding - + - + - - - - response to mechanical stimulus - + - + - - - response to abiotic stimulus - + - + - - - response to gravity - + - + - - - - - - - - - anatomical structure morphogenesis - + - + - - - catechol-containing compound metabolic process - + - + - - - embryo development - + - + - - - - - - - - - post-embryonic development - + - + - - - embryo development ending in birth or egg hatching - + - + - - - - - - - - - animal organ morphogenesis - + - + - - - tissue development + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms. + GO:0019952 + GO:0050876 + Wikipedia:Reproduction + reproductive physiological process + biological_process + GO:0000003 + + + + + + reproduction + + + + The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms. + GOC:go_curators + GOC:isa_complete + GOC:jl + ISBN:0198506732 + - + - + - + - - + + - + + + + + + + + + + + - - + + + + + + - regulation of biosynthetic process + + + + + + + The distribution of vacuoles into daughter cells after mitosis or meiosis, mediated by interactions between vacuoles and the cytoskeleton. + + biological_process + GO:0000011 + vacuole inheritance + + + + The distribution of vacuoles into daughter cells after mitosis or meiosis, mediated by interactions between vacuoles and the cytoskeleton. + GOC:mcc + PMID:10873824 + PMID:14616069 + - + - + - + - - + + - - - - - - - - - negative regulation of biosynthetic process + + + The lipid bilayer surrounding any of the compartments of the Golgi apparatus. + cellular_component + GO:0000139 + Golgi membrane + + + + The lipid bilayer surrounding any of the compartments of the Golgi apparatus. + GOC:mah + - + - + - + - - + + - - - - - - - - - positive regulation of biosynthetic process - + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins. + https://github.com/geneontology/go-ontology/issues/23114 + microtubule cytoskeleton organisation + microtubule dynamics + biological_process + microtubule cytoskeleton organization and biogenesis + GO:0000226 + + microtubule cytoskeleton organization + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins. + GOC:mah + + + + + microtubule cytoskeleton organisation + GOC:mah + + + + + microtubule dynamics + GOC:dph + GOC:tb + + + + + microtubule cytoskeleton organization and biogenesis + GOC:mah + - + - + - + - - + + - - - - - - - - - negative regulation of metabolic process + + + + The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. + glycan biosynthesis + glycan biosynthetic process + polysaccharide anabolism + polysaccharide biosynthesis + polysaccharide formation + polysaccharide synthesis + biological_process + GO:0000271 + polysaccharide biosynthetic process + + + + The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. + GOC:go_curators + - + - + - + - - + + - - - - - - - - - positive regulation of metabolic process + The chemical reactions and pathways resulting in the breakdown of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. + GO:0044244 + polysaccharide breakdown + polysaccharide catabolism + polysaccharide degradation + multicellular organismal polysaccharide catabolic process + biological_process + GO:0000272 + polysaccharide catabolic process + + + + The chemical reactions and pathways resulting in the breakdown of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. + PMID:33139480 + - + - + - + - - + + - - - - - - - - regulation of catabolic process + The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei. + biological_process + karyokinesis + GO:0000280 + + nuclear division + + + + The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei. + GOC:mah + - + - + + + + The establishment, maintenance and elaboration of a pattern along a line or a point in an embryo. + biological_process + embryonic axis determination + GO:0000578 + embryonic axis specification + + + + + The establishment, maintenance and elaboration of a pattern along a line or a point in an embryo. + GOC:dph + GOC:go_curators + GOC:sdb_2009 + GOC:tb + + + + + + + - + - - + + - - - - - - - - - negative regulation of catabolic process + The joining of 2 or more lipid bilayer membranes that surround the nucleus. + biological_process + GO:0000740 + nuclear membrane fusion + + + + The joining of 2 or more lipid bilayer membranes that surround the nucleus. + GOC:elh + - + - + - + - - + + - - - - - - - - - positive regulation of catabolic process - - - - - - - - - + - epidermal cell differentiation + The creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei. + GO:0007335 + Wikipedia:Karyogamy + nuclear fusion + nuclear fusion during karyogamy + biological_process + GO:0000741 + karyogamy + + + + The creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei. + GOC:elh + - + - - - - hormone transport + + + + + + + + + + + + + + The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells. + cell fusion + biological_process + GO:0000768 + syncytium formation by plasma membrane fusion + + + + The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells. + GOC:mtg_muscle + GOC:tb + - + - + - + - - - - - - - - - - regulation of signal transduction + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline. + regulation of glutamine family amino acid metabolism + biological_process + GO:0000820 + regulation of glutamine family amino acid metabolic process + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline. + GOC:go_curators + - + - + - + - - + + - - - - - - - - - - - positive regulation of signal transduction + The developmental process in which the size or shape of a cell is generated and organized. + GO:0007148 + GO:0045790 + GO:0045791 + cellular morphogenesis + biological_process + GO:0000902 + + + + cell morphogenesis + + + + The developmental process in which the size or shape of a cell is generated and organized. + GOC:clt + GOC:dph + GOC:go_curators + GOC:tb + - + - + - + - - + + - - - - - - - - - - - negative regulation of signal transduction + The change in form (cell shape and size) that occurs when relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. + biological_process + GO:0000904 + cell morphogenesis involved in differentiation + + + + The change in form (cell shape and size) that occurs when relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. + GOC:go_curators + - + - - - cellular process + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form. + response to acid + biological_process + response to acid anion + response to oxoanion + GO:0001101 + + This term should be used to describe a response to a specific acid as a chemical. E.g., if an organism were responding to glutamate, then the response would be glutamate-specific; the organism is actually responding to the chemical structure of the anion portion of the dissociated acid. Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. If annotating experiments where an acid is playing a role as a proton donor, please annotate to GO:0010447 'response to acidic pH' instead. + response to acid chemical + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form. + GOC:go_curators + GOC:rn + - + - - - response to organic substance + + + + + + + + + + + + + + The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton). + skeletal development + biological_process + GO:0001501 + skeletal system development + + + + The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton). + GOC:dph + GOC:jid + GOC:tb + - + - - - response to inorganic substance + + + + + + + + + + + + + + The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance. + Wikipedia:Ossification + bone biosynthesis + bone formation + osteogenesis + biological_process + GO:0001503 + Note that this term does not have a 'developmental process' parent because ossification isn't necessarily developmental, can also occur as part of bone remodeling. Instead use 'ossification involved in bone maturation ; GO:0043931'. + ossification + + + + The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance. + GOC:mtg_mpo + PMID:17572649 + - + - - - mesenchymal cell proliferation + + + + + + + + + + + + + Any process that modulates levels of neurotransmitter. + biological_process + GO:0001505 + regulation of neurotransmitter levels + + + + Any process that modulates levels of neurotransmitter. + GOC:jl + - + - + - + - - + + - + + - - + + - regulation of mesenchymal cell proliferation + Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels. + Wikipedia:Angiogenesis + blood vessel formation from pre-existing blood vessels + biological_process + GO:0001525 + angiogenesis + + + + Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels. + ISBN:0878932453 + + + + + blood vessel formation from pre-existing blood vessels + + - + - - - gene expression + + + Cell motility due to movement of eukaryotic cilia or bacterial-type flagella or archaeal-type flagella. + ciliary/flagellar motility + biological_process + ciliary or bacterial-type flagellar motility + GO:0001539 + + Note that we deem eukaryotic cilia and microtubule-based flagella to be equivalent, while the bacterial- and archaeal-type flagella have a different structure. The former are microtubule-based structures that lash back and forth and are present only in eukaryotes, while the latter achieve motility by rotation. Bacterial- and archaeal-type flagella are superficially similar but have a different molecular composition and fine structure. These three structures never co-exist in the same organism. Therefore, GO:0001539 'cilium or flagellum-dependent cell motility' is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term. Direct annotations to GO:0001539 'cilium or flagellum-dependent cell motility' may be amended during annotation QC. + cilium or flagellum-dependent cell motility + + + + Cell motility due to movement of eukaryotic cilia or bacterial-type flagella or archaeal-type flagella. + GOC:cilia + GOC:hjd + GOC:krc + - + - + - + - - + + - - - + + - regulation of gene expression + The process whose specific outcome is the progression of the ovarian follicle over time, from its formation to the mature structure. + biological_process + follicular phase + GO:0001541 + ovarian follicle development + + + + The process whose specific outcome is the progression of the ovarian follicle over time, from its formation to the mature structure. + https://www.ncbi.nlm.nih.gov/books/NBK279054/ + - + - + - + - - + + - - + - - + + - regulation of signaling receptor activity + Increase in size of primary follicles including oocyte growth and granulosa and/or theca cell proliferation until more than one layer of granulosa cells is present (preantral follicle). + biological_process + GO:0001545 + primary ovarian follicle growth + + + + Increase in size of primary follicles including oocyte growth and granulosa and/or theca cell proliferation until more than one layer of granulosa cells is present (preantral follicle). + GOC:mtg_mpo + https://www.ncbi.nlm.nih.gov/books/NBK279054/ + - + - + - + - - + + - - + - - + + - regulation of gastrulation + + + + + + + Increase in size of follicles surrounded by two or more layers of granulosa cells up to the onset of antrum formation. + biological_process + GO:0001546 + preantral ovarian follicle growth + + + + Increase in size of follicles surrounded by two or more layers of granulosa cells up to the onset of antrum formation. + https://www.ncbi.nlm.nih.gov/books/NBK279054/ + - + - + - + - - + + - - + + + - - + + - regulation of macromolecule biosynthetic process + Increase in size of antral follicles due to cell proliferation and/or growth of the antral cavity. + biological_process + GO:0001547 + antral ovarian follicle growth + + + + Increase in size of antral follicles due to cell proliferation and/or growth of the antral cavity. + https://www.ncbi.nlm.nih.gov/books/NBK279054/ + - + - + - + - - + + - - - + - - + + - positive regulation of macromolecule biosynthetic process + + + + + + + Increase in size of the cumulus surrounding the oocyte including change in morphology due to proliferation and dispersion of cumulus cells. + biological_process + ovarian cumulus growth + GO:0001550 + ovarian cumulus expansion + + + + Increase in size of the cumulus surrounding the oocyte including change in morphology due to proliferation and dispersion of cumulus cells. + PMID:30010832 + - + - - - - - - - - - - - - - - - + + - - + + - negative regulation of macromolecule biosynthetic process + The set of processes resulting in differentiation of theca and granulosa cells into luteal cells and in the formation of a corpus luteum after ovulation. + Wikipedia:Luteal_phase + Wikipedia:Luteinization + biological_process + luteal phase + GO:0001553 + luteinization + + + + The set of processes resulting in differentiation of theca and granulosa cells into luteal cells and in the formation of a corpus luteum after ovulation. + https://www.ncbi.nlm.nih.gov/books/NBK279054/ + - + - + - + - - + + - + + - - + + - regulation of cell cycle process + + + + + + + + + + + + + The developmental growth process in which an oocyte irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present. + biological_process + GO:0001555 + oocyte growth + + + + The developmental growth process in which an oocyte irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present. + https://www.ncbi.nlm.nih.gov/books/NBK279054/ + - + - + - + - - + + - - + + - - + + - regulation of cellular ketone metabolic process + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for an oocyte to attain its fully functional state. Oocyte maturation commences after reinitiation of meiosis commonly starting with germinal vesicle breakdown, and continues up to the second meiotic arrest prior to fertilization. + Wikipedia:Oocyte_maturation + biological_process + GO:0001556 + oocyte maturation + + + + A developmental process, independent of morphogenetic (shape) change, that is required for an oocyte to attain its fully functional state. Oocyte maturation commences after reinitiation of meiosis commonly starting with germinal vesicle breakdown, and continues up to the second meiotic arrest prior to fertilization. + GOC:devbiol + https://www.ncbi.nlm.nih.gov/books/NBK279054/ + - + - + - + - - - - - - - - - regulation of ketone biosynthetic process + + + Any process that modulates the frequency, rate, extent or direction of cell growth. + biological_process + GO:0001558 + regulation of cell growth + + + + Any process that modulates the frequency, rate, extent or direction of cell growth. + GOC:go_curators + - + - + - + - - + + - - + + - - + + - positive regulation of macromolecule metabolic process + The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood. + biological_process + GO:0001568 + blood vessel development + + + + The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood. + GOC:hjd + UBERON:0001981 + - + - + - + - - + + - - + - - + + - negative regulation of macromolecule metabolic process + The process of coordinated growth and sprouting of blood vessels giving rise to the organized vascular system. + patterning of blood vessels + biological_process + GO:0001569 + branching involved in blood vessel morphogenesis + + + + The process of coordinated growth and sprouting of blood vessels giving rise to the organized vascular system. + GOC:dph + + + + + patterning of blood vessels + GOC:dph + - + - + - + - - + + - - + - - + + - positive regulation of gene expression + The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes. + Wikipedia:Vasculogenesis + vascular morphogenesis + biological_process + GO:0001570 + vasculogenesis + + + + The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes. + PMID:8999798 + - + - - - - - - - - - - - - - - + + - - + + - negative regulation of gene expression + + + + + + + A process that results in a parallel arrangement of microtubules. + microtubule bundling + biological_process + GO:0001578 + microtubule bundle formation + + + + A process that results in a parallel arrangement of microtubules. + GOC:dph + - + - + - + - - + + - - + - - + + - positive regulation of organelle organization + The process whereby a relatively unspecialized cell acquires the specialized features of an osteoblast, a mesodermal or neural crest cell that gives rise to bone. + osteoblast cell differentiation + biological_process + GO:0001649 + osteoblast differentiation + + + + The process whereby a relatively unspecialized cell acquires the specialized features of an osteoblast, a mesodermal or neural crest cell that gives rise to bone. + CL:0000062 + GOC:jid + GO_REF:0000034 + - + - + - + - - + + - - + - - + + - negative regulation of organelle organization + Combining with an extracellular or intracellular peptide to initiate a change in cell activity. + endogenous peptide receptor activity + exogenous peptide receptor activity + molecular_function + GO:0001653 + peptide receptor activity + + + + Combining with an extracellular or intracellular peptide to initiate a change in cell activity. + GOC:jl + - + - + - + - - + + - + - - + + - regulation of cell communication + The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight. + GO:0042460 + Wikipedia:Eye_development + biological_process + GO:0001654 + eye development + + + + The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight. + GOC:jid + GOC:jl + - + - + - + - - + + - - - - - - - - - positive regulation of cell communication + + The process whose specific outcome is the progression of the urogenital system over time, from its formation to the mature structure. + biological_process + GO:0001655 + urogenital system development + + + + The process whose specific outcome is the progression of the urogenital system over time, from its formation to the mature structure. + GOC:go_curators + - + - + - + - - + + - - - - - - - - - negative regulation of cell communication + + The process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. In mammals, the metanephros is the excretory organ of the fetus, which develops into the mature kidney and is formed from the rear portion of the nephrogenic cord. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine. + biological_process + GO:0001656 + metanephros development + + + + The process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. In mammals, the metanephros is the excretory organ of the fetus, which develops into the mature kidney and is formed from the rear portion of the nephrogenic cord. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine. + GOC:bf + ISBN:0192800752 + - + - + - + - - + + - - + - - + + - regulation of cellular carbohydrate metabolic process + The process whose specific outcome is the progression of the ureteric bud over time, from its formation to the mature structure. + biological_process + GO:0001657 + ureteric bud development + + + + The process whose specific outcome is the progression of the ureteric bud over time, from its formation to the mature structure. + GOC:go_curators + - + - + - + - - + + - - - - - - - - - - positive regulation of cellular carbohydrate metabolic process + + The process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules. + ureteric bud branching + biological_process + GO:0001658 + branching involved in ureteric bud morphogenesis + + + + + The process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules. + GOC:dph + PMID:16916378 + + + + + ureteric bud branching + GOC:dph + + + + + + + + + A homeostatic process in which an organism modulates its internal body temperature. + Wikipedia:Thermoregulation + thermoregulation + biological_process + GO:0001659 + temperature homeostasis + + + + A homeostatic process in which an organism modulates its internal body temperature. + GOC:jl + + + + + thermoregulation + GOC:dph + GOC:tb + - + - + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. + response to hypoxic stress + response to lowered oxygen tension + response to intermittent hypoxia + response to sustained hypoxia + biological_process + GO:0001666 + Note that this term should not be confused with 'response to anoxia ; GO:0034059'. Note that in laboratory studies, hypoxia is typically studied at O2 concentrations ranging from 0.1 - 5%. + response to hypoxia + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. + GOC:hjd + + + + + + + + + Cell migration that is accomplished by extension and retraction of a pseudopodium. + ameboid cell migration + amoeboid cell migration + amoeboidal cell migration + biological_process + GO:0001667 + Note that this term refers to a mode of migration rather than to any particular cell type. + ameboidal-type cell migration + + + + + Cell migration that is accomplished by extension and retraction of a pseudopodium. + GOC:dph + + + + + + + - + - - + + - - - + - - + + - negative regulation of cellular carbohydrate metabolic process + + + + + + + The nucleus of the female germ cell, a reproductive cell in females. + GO:0043080 + female germ-cell nucleus + cellular_component + GO:0001674 + female germ cell nucleus + + + + The nucleus of the female germ cell, a reproductive cell in females. + CL:0000021 + GOC:hjd + - + - + - + - - + + - - - - - - - - - negative regulation of norepinephrine secretion + A cellular homeostatic process involved in the maintenance of an internal steady state of glucose within a cell or between a cell and its external environment. + cell glucose homeostasis + biological_process + GO:0001678 + cellular glucose homeostasis + + + + A cellular homeostatic process involved in the maintenance of an internal steady state of glucose within a cell or between a cell and its external environment. + GOC:dph + GOC:go_curators + GOC:tb + + + + + cell glucose homeostasis + GOC:dph + GOC:tb + - + - + - + - - + + - - - - - - - - - positive regulation of norepinephrine secretion + + + + The chemical reactions and pathways involving histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans. + histamine metabolism + biological_process + GO:0001692 + histamine metabolic process + + + + The chemical reactions and pathways involving histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans. + GOC:jl + ISBN:0395825172 + - + - + - + - - + + - - - - - - - - - positive regulation of cell development + + The chemical reactions and pathways resulting in the formation of histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans. + GO:0001693 + histamine anabolism + histamine biosynthesis + histamine formation + histamine synthesis + biological_process + GO:0001694 + histamine biosynthetic process + + + + The chemical reactions and pathways resulting in the formation of histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans. + GOC:jl + ISBN:0395825172 + - + - + - + - - + + - - - - - - - + + + The chemical reactions and pathways resulting in the breakdown of histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans. + histamine breakdown + histamine catabolism + histamine degradation + biological_process + GO:0001695 + histamine catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans. + GOC:jl + ISBN:0395825172 + + + + + + + + + + + The regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion. + hydrochloric acid secretion + biological_process + GO:0001696 + gastric acid secretion + + + + + The regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion. + GOC:hjd + + + + + + + + + + + + + - negative regulation of cell development + + + + + + + The process whose specific outcome is the progression of the embryo over time, from zygote formation through syncytial blastoderm to the hatching of the first instar larva. An example of this process is found in Drosophila melanogaster. + biological_process + GO:0001700 + embryonic development via the syncytial blastoderm + + + + The process whose specific outcome is the progression of the embryo over time, from zygote formation through syncytial blastoderm to the hatching of the first instar larva. An example of this process is found in Drosophila melanogaster. + GOC:go_curators + GOC:mtg_sensu + - + - - - regulation of hormone levels + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus. + biological_process + GO:0001701 + in utero embryonic development + + + + The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus. + GOC:go_curators + GOC:mtg_sensu + - + - + + + + + + + + + + + + + + + A gastrulation process in which the initial invagination becomes the anus and the mouth forms second. + GO:0010003 + GO:0048276 + deuterostomic gastrulation + biological_process + GO:0001702 + gastrulation with mouth forming second + + + + + A gastrulation process in which the initial invagination becomes the anus and the mouth forms second. + GOC:go_curators + GOC:mtg_sensu + + + + + deuterostomic gastrulation + GOC:dph + + + + + + + + + + + + + + + + + + + + + A gastrulation process in which the initial invagination becomes the mouth and the anus forms second. + protostomic gastrulation + biological_process + GO:0001703 + gastrulation with mouth forming first + + + + + A gastrulation process in which the initial invagination becomes the mouth and the anus forms second. + GOC:go_curators + GOC:mtg_sensu + + + + + protostomic gastrulation + GOC:dph + + + + + + + - + - - + + - + + - - + + - regulation of keratinocyte proliferation + The formation of the ectoderm, mesoderm and endoderm during gastrulation. + biological_process + GO:0001704 + formation of primary germ layer + + + + The formation of the ectoderm, mesoderm and endoderm during gastrulation. + GOC:go_curators + - + - + - + - - + + - - + - - + + - positive regulation of keratinocyte proliferation + The formation of ectoderm during gastrulation. + biological_process + GO:0001705 + ectoderm formation + + + + The formation of ectoderm during gastrulation. + GOC:go_curators + - + - + - + - - + + - - + - - + + - negative regulation of keratinocyte proliferation - - - - - - - - - lipid localization + The formation of the endoderm during gastrulation. + endoblast formation + biological_process + GO:0001706 + endoderm formation + + + + The formation of the endoderm during gastrulation. + GOC:go_curators + + + + + endoblast formation + GOC:dph + GOC:sdb_2009 + GOC:tb + - + - + - + - - + + - - - + - - + + - positive regulation of steroid biosynthetic process + The process that gives rise to the mesoderm. This process pertains to the initial formation of the structure from unspecified parts. + biological_process + GO:0001707 + mesoderm formation + + + + The process that gives rise to the mesoderm. This process pertains to the initial formation of the structure from unspecified parts. + GOC:go_curators + - + - + - + - - + + - - - - - - - - - - negative regulation of steroid biosynthetic process + + The morphogenetic process in which the anatomical structures of a polarized epithelium are generated and organized. A polarized epithelium is an epithelium where the epithelial sheet is oriented with respect to the planar axis. + epithelial polarization + biological_process + GO:0001738 + morphogenesis of a polarized epithelium + + + + The morphogenetic process in which the anatomical structures of a polarized epithelium are generated and organized. A polarized epithelium is an epithelium where the epithelial sheet is oriented with respect to the planar axis. + GOC:dph + + + + + epithelial polarization + GOC:dph + - + - + - + - - + + - - + - - + + - regulation of glucose metabolic process + The initial developmental process that will lead to the formation of an eye. + biological_process + optic placode formation + GO:0001743 + lens placode formation + + + + The initial developmental process that will lead to the formation of an eye. + GOC:dph + - + - + - + - - + + - - - + - - + + - positive regulation of glucose metabolic process + Establishment of the optic lobe placode. In Drosophila, for example, the placode appears in the dorsolateral region of the head in late stage 11 embryos and is the precursor to the larval visual system. + GO:0007457 + optic lobe and Bolwig's organ precursor formation + optic lobe placode formation + biological_process + GO:0001744 + insect visual primordium formation + + + + Establishment of the optic lobe placode. In Drosophila, for example, the placode appears in the dorsolateral region of the head in late stage 11 embryos and is the precursor to the larval visual system. + GOC:mtg_sensu + PMID:8402833 + - + - + - + - - + + - - + - - + + - negative regulation of cell cycle process + + + + + + + + + + + + + The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster. + insect-type retina morphogenesis + biological_process + GO:0001745 + compound eye morphogenesis + + + + The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster. + GOC:dph + GOC:mtg_sensu + + + + + insect-type retina morphogenesis + PMID:11735386 + - + - + - + - - + + - - - + + - - + + - regulation of glucan biosynthetic process + + + + + + + The process whose specific outcome is the progression of the optic placode over time, from its formation to the mature structure. During embryonic stage 12 the placode starts to invaginate, forming a pouch. Cells that will form Bolwig's organ segregate from the ventral lip of this pouch, remaining in the head epidermis. The remainder of the invagination loses contact with the outer surface and becomes the optic lobe. An example of this process is found in Drosophila melanogaster. + GO:0048049 + optic placode development + optic lobe and Bolwig's organ precursor development + optic lobe placode development + biological_process + GO:0001748 + insect visual primordium development + + + + The process whose specific outcome is the progression of the optic placode over time, from its formation to the mature structure. During embryonic stage 12 the placode starts to invaginate, forming a pouch. Cells that will form Bolwig's organ segregate from the ventral lip of this pouch, remaining in the head epidermis. The remainder of the invagination loses contact with the outer surface and becomes the optic lobe. An example of this process is found in Drosophila melanogaster. + GOC:mtg_sensu + PMID:8402833 + - + - + - - + + - - + + - endomembrane system + + + + + + + + + + + + + The outer segment of a vertebrate photoreceptor that contains a stack of membrane discs embedded with photoreceptor proteins. + cellular_component + GO:0001750 + photoreceptor outer segment + + + + The outer segment of a vertebrate photoreceptor that contains a stack of membrane discs embedded with photoreceptor proteins. + GOC:cilia + GOC:krc + GOC:pde + ISBN:0824072820 + PMID:19501669 + PMID:26574505 + PMID:6771304 + - + - + - + - - + + - + - + - vesicle membrane + The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell, as found in the eye, the primary visual organ of most organisms. + biological_process + GO:0001754 + eye photoreceptor cell differentiation + + + + The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell, as found in the eye, the primary visual organ of most organisms. + GOC:go_curators + - + - - + + + + + + + + + + + + + + - + - primary neural tube formation + The characteristic movement of cells from the dorsal ridge of the neural tube to a variety of locations in a vertebrate embryo. + biological_process + GO:0001755 + neural crest cell migration + + + + The characteristic movement of cells from the dorsal ridge of the neural tube to a variety of locations in a vertebrate embryo. + GOC:ascb_2009 + GOC:dph + GOC:tb + ISBN:0878932437 + - + - + - + - - + + - + + + - - + + - regulation of norepinephrine secretion + + + + + + + The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo. + Wikipedia:Somitogenesis + formation of mesodermal clusters + biological_process + GO:0001756 + somitogenesis + + + + The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo. + ISBN:0721662544 + + + + + formation of mesodermal clusters + + - + - + + + + + The process in which the anatomical structures of branches are generated and organized. A branch is a division or offshoot from a main stem. Examples in animals would include blood vessels, nerves, lymphatics and other endothelial or epithelial tubes. + branching morphogenesis + biological_process + GO:0001763 + morphogenesis of a branching structure + + + + + The process in which the anatomical structures of branches are generated and organized. A branch is a division or offshoot from a main stem. Examples in animals would include blood vessels, nerves, lymphatics and other endothelial or epithelial tubes. + ISBN:0721662544 + + + + + branching morphogenesis + GOC:dph + + + + + + + - + - - + + - - + - - + + - regulation of serotonin secretion + The characteristic movement of an immature neuron from germinal zones to specific positions where they will reside as they mature. + Wikipedia:Neural_development#Neuron_migration + Wikipedia:Neuron_migration + neuron chemotaxis + neuronal migration + biological_process + neuron guidance + GO:0001764 + neuron migration + + + + The characteristic movement of an immature neuron from germinal zones to specific positions where they will reside as they mature. + CL:0000540 + GOC:go_curators + - + - + - + - - + + - - - + - - + + - negative regulation of serotonin secretion + The directed orientation of lymphocyte signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with an appropriate activating cell. + lymphocyte polarization + biological_process + GO:0001767 + establishment of lymphocyte polarity + + + + The directed orientation of lymphocyte signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with an appropriate activating cell. + GOC:mgi_curators + PMID:11244041 + PMID:12615889 + - + - + - + - - + + - - - + - - + + - positive regulation of serotonin secretion + The directed orientation of T cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with antigen presenting cell. + T cell polarization + T lymphocyte polarization + T-cell polarization + establishment of T lymphocyte polarity + establishment of T-cell polarity + establishment of T-lymphocyte polarity + biological_process + GO:0001768 + establishment of T cell polarity + + + + The directed orientation of T cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with antigen presenting cell. + GOC:mgi_curators + PMID:11244041 + PMID:12615889 + - + - - - phasic smooth muscle contraction + + + + + + + + + + + + + + + + + + + + The directed orientation of B cell signaling molecules and associated membrane rafts towards a chemokine gradient of a contact point with an antigen displaying cell. + B cell polarization + B lymphocyte polarization + B-cell polarization + establishment of B lymphocyte polarity + establishment of B-cell polarity + establishment of B-lymphocyte polarity + biological_process + GO:0001769 + Note that 'antigen displaying cell' in this term encompasses cell types such as follicular dendritic cells which display the unprocessed antigens of a B cell, leading to activation of the B cells and antigen uptake and processing by the B cells. + establishment of B cell polarity + + + + The directed orientation of B cell signaling molecules and associated membrane rafts towards a chemokine gradient of a contact point with an antigen displaying cell. + GOC:mgi_curators + PMID:12615889 + PMID:9692889 + - + - - - urinary bladder smooth muscle contraction + + + + + + + + + + + + + + The change in morphology and behavior of a dendritic cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. + biological_process + GO:0001773 + myeloid dendritic cell activation + + + + The change in morphology and behavior of a dendritic cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. + GOC:mgi_curators + ISBN:0781735149 + - + - - - urinary tract smooth muscle contraction + + + A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand. + biological_process + GO:0001775 + + cell activation + + + + A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand. + GOC:mgi_curators + - + - - - - - protein transport + + + + + + + + + + + + + + + The process of regulating the proliferation and elimination of cells of the immune system such that the total number of cells of a particular cell type within a whole or part of an organism is stable over time in the absence of an outside stimulus. + immune cell homeostasis + leucocyte homeostasis + biological_process + GO:0001776 + Note that this term represents the return of immune system cell levels to stable numbers following an immune response as well as the proliferation and elimination of cells of the immune system required to maintain stable numbers in the absence of an outside stimulus. + leukocyte homeostasis + + + + The process of regulating the proliferation and elimination of cells of the immune system such that the total number of cells of a particular cell type within a whole or part of an organism is stable over time in the absence of an outside stimulus. + GOC:add + ISBN:0781735149 + - + - - - actin cytoskeleton + + + + + + + + + + + + + + + + + + + + + + + + The non-specific expansion of T cell populations within a whole or part of an organism to reach to a total number of T cells which will then remain stable over time in the absence of an external stimulus. + T lymphocyte homeostatic proliferation + T-cell homeostatic proliferation + T-lymphocyte homeostatic proliferation + resting T cell proliferation + resting T-cell proliferation + biological_process + GO:0001777 + T cell homeostatic proliferation + + + + The non-specific expansion of T cell populations within a whole or part of an organism to reach to a total number of T cells which will then remain stable over time in the absence of an external stimulus. + GOC:mgi_curators + ISBN:0781735149 + - + - - - - organic anion transport + + + + + + + + + + + + + + The process of regulating the proliferation and elimination of B cells such that the total number of B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. + B lymphocyte homeostasis + B-cell homeostasis + B-lymphocyte homeostasis + biological_process + GO:0001782 + Note that this term represents the return of B cell levels to stable numbers following an immune response as well as the proliferation and elimination of B cells required to maintain stable numbers in the absence of an outside stimulus. + B cell homeostasis + + + + The process of regulating the proliferation and elimination of B cells such that the total number of B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. + GOC:add + ISBN:0781735149 + PMID:12956429 + - + - - - monocarboxylic acid transport + + + + + + + + + + + + + + + + The regulated release of serotonin by a cell. Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine synthesised in serotonergic neurons in the central nervous system, enterochromaffin cells in the gastrointestinal tract and some immune system cells. + 5-HT secretion + 5-hydroxytryptamine secretion + biological_process + serotonin release + GO:0001820 + serotonin secretion + + + + The regulated release of serotonin by a cell. Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine synthesised in serotonergic neurons in the central nervous system, enterochromaffin cells in the gastrointestinal tract and some immune system cells. + GOC:ef + ISBN:0198506732 + ISBN:0781735149 + + + + + serotonin release + GOC:tb + - + - - - - - - bile acid and bile salt transport + + + + + + + + + + + + + The regulated release of histamine by a cell or tissue. It is formed by decarboxylation of histidine and it acts through receptors in smooth muscle and in secretory systems. + biological_process + GO:0001821 + histamine secretion + + + + The regulated release of histamine by a cell or tissue. It is formed by decarboxylation of histidine and it acts through receptors in smooth muscle and in secretory systems. + GOC:mah + ISBN:0198506732 + ISBN:0781735149 + - + - - - - peptide transport + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine. + Wikipedia:Kidney_development + biological_process + nephrogenesis + GO:0001822 + kidney development + + + + The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine. + GOC:dph + GOC:mtg_kidney_jan10 + ISBN:0124020607 + ISBN:0721662544 + + + + + nephrogenesis + GOC:rph + - + - - - - amine transport + + + + + + + + + + + + + + The process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. In mammals, the mesonephros is the second of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the mesonephros will form the mature kidney. + Wolffian body development + biological_process + GO:0001823 + mesonephros development + + + + The process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. In mammals, the mesonephros is the second of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the mesonephros will form the mature kidney. + GOC:dph + ISBN:0124020607 + ISBN:0721662544 + PMID:10535314 + + + + + Wolffian body development + GOC:dph + - + - - - - monoamine transport + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the blastocyst over time, from its formation to the mature structure. The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm. + biological_process + GO:0001824 + See also the Anatomical Dictionary for Mouse Development ontology terms 'TS5, embryo ; EMAP:23', 'TS5, inner cell mass ; EMAP:24' and 'TS5, trophectoderm; EMAP:28'. + blastocyst development + + + + The process whose specific outcome is the progression of the blastocyst over time, from its formation to the mature structure. The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm. + GOC:dph + ISBN:0124020607 + ISBN:0198542771 + - + - - - organic acid transport + + + + + + + + + + + + + + + + + + + + + The initial formation of a blastocyst from a solid ball of cells known as a morula. + biological_process + GO:0001825 + See also the Anatomical Dictionary for Mouse Development ontology term 'TS3, compacted morula ; EMAP:9'. + blastocyst formation + + + + The initial formation of a blastocyst from a solid ball of cells known as a morula. + GOC:dph + ISBN:0124020607 + ISBN:0198542771 + - + - - - organic hydroxy compound transport - - - - - - - - - norepinephrine transport - - - - - - - - - energy derivation by oxidation of organic compounds - - - - - - - - - membrane - - - - - - - - - cellular component organization - - - - - - - - - - - detection of temperature stimulus - - - - - - - - - - cell growth - - - - - - - - - vesicle organization - - - - - - - - - - carbohydrate biosynthetic process - - - - - - - - - - carbohydrate catabolic process - - - - - - - - - - - - organic acid biosynthetic process - - - - - - - - - - vesicle-mediated transport - - - - - - - - - - morphogenesis of embryonic epithelium - - - - - - - - - cell migration - - - - - - - + - + - - + + - - + - - + + - negative regulation of angiogenesis - - - - - - - - - stem cell division + The process in which a relatively unspecialized cell acquires the specialized features of a trophectoderm cell. + trophectoderm cell differentiation + biological_process + GO:0001829 + See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19'. + trophectodermal cell differentiation + + + + The process in which a relatively unspecialized cell acquires the specialized features of a trophectoderm cell. + GOC:dph + ISBN:0124020607 + ISBN:0198542771 + - + - + - + - - + + - - + + - - + + - regulation of exocytosis - - - - - - - - - - heterocycle biosynthetic process - - - - - - - - - - - phenol-containing compound metabolic process - - - - - - - - - - - - - - - - - - - - - reproductive behavior + The morphogenesis of trophectoderm cells. + trophectoderm cellular morphogenesis + biological_process + GO:0001831 + See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19', 'TS5, trophectoderm ; EMAP:28' and 'TS6, trophectoderm ; EMAP:39'. + trophectodermal cellular morphogenesis + + + + The morphogenesis of trophectoderm cells. + GOC:dph + ISBN:0124020607 + ISBN:0198542771 + - + - + - + - - + + - + - - + + - regulation of lipid metabolic process + An increase in size of a blastocyst due to expansion of the blastocoelic cavity cell shape changes and cell proliferation. + biological_process + GO:0001832 + See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, blastocoelic cavity ; EMAP:17', 'TS5, blastocoelic cavity ; EMAP:27' and 'TS6, blastocoelic cavity ; EMAP:36'. + blastocyst growth + + + + An increase in size of a blastocyst due to expansion of the blastocoelic cavity cell shape changes and cell proliferation. + GOC:dph + ISBN:0124020607 + ISBN:0198542771 + - + - + - + - - + + - + - - + + - regulation of steroid metabolic process + The proliferation of cells in the trophectoderm. + trophectoderm cell proliferation + biological_process + GO:0001834 + See also the Anatomical Dictionary for Mouse Development ontology terms 'TS4, trophectoderm ; EMAP:19', 'TS5, trophectoderm ; EMAP:28' and 'TS6, trophectoderm ; EMAP:39'. + trophectodermal cell proliferation + + + + The proliferation of cells in the trophectoderm. + GOC:dph + ISBN:0124020607 + ISBN:0198542771 + - + - + - + - - + + + + + + - + - - + + - regulation of metabolic process + A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. + EMT + epithelial-mesenchymal transition + mesenchymal cell differentiation from epithelial cell + biological_process + GO:0001837 + epithelial to mesenchymal transition + + + + A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. + GOC:dph + PMID:14701881 + + + + + mesenchymal cell differentiation from epithelial cell + GOC:BHF + GOC:dph + GOC:rl + - + - - + + - + - proprioception - - - - - - - - - sensory perception of pain - - - - - - - - - response to pheromone - - - - - - - - - hexose metabolic process - - - - - - - - - - aromatic compound biosynthetic process - - - - - - - - - - choline metabolic process - - - - - - - - - carboxylic acid metabolic process - - - - - - - - - - sexual reproduction + The morphogenesis of an embryonic epithelium into a tube-shaped structure. + biological_process + GO:0001838 + embryonic epithelial tube formation + + + + The morphogenesis of an embryonic epithelium into a tube-shaped structure. + GOC:dph + ISBN:0824072820 + - + - + + + + + + + + + + + + - + - anterior neuropore closure - - - - - - - - - developmental maturation + The process in which the anatomical structures of the neural plate are generated and organized. The neural plate is a specialized region of columnar epithelial cells in the dorsal ectoderm that will give rise to nervous system tissue. + biological_process + GO:0001839 + neural plate morphogenesis + + + + The process in which the anatomical structures of the neural plate are generated and organized. The neural plate is a specialized region of columnar epithelial cells in the dorsal ectoderm that will give rise to nervous system tissue. + GOC:dph + ISBN:0878932437 + - + - - + + + + + + + + + + + + - - - - - - - neural tube development - - - - - - - - - - - - - - - neuropore closure + The process whose specific outcome is the progression of the neural plate over time, from its formation to the mature structure. The neural plate is a flat, thickened layer of ectodermal cells. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system. + biological_process + GO:0001840 + neural plate development + + + + The process whose specific outcome is the progression of the neural plate over time, from its formation to the mature structure. The neural plate is a flat, thickened layer of ectodermal cells. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system. + GOC:dph + GOC:ef + ISBN:0878932437 + ISBN:0878932585 + - + - - + + + + + + + + + + + + + - + - neurogenesis + The formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system. + GO:0001679 + Wikipedia:Neurulation + neural tube morphogenesis + neurulation + biological_process + GO:0001841 + neural tube formation + + + + The formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system. + GOC:dph + ISBN:0878932437 + + + + + neural tube morphogenesis + GOC:dph + - + - + - + - - + + - + + - + - cell cycle process + The process in which the neural fold is formed. The edges of the neural plate thicken and move up to form a U-shaped structure called the neural groove. + biological_process + neural groove formation + GO:0001842 + neural fold formation + + + + The process in which the neural fold is formed. The edges of the neural plate thicken and move up to form a U-shaped structure called the neural groove. + GOC:dph + ISBN:0878932437 + + + + + neural groove formation + GOC:dph + - + - + - + - - + + - + - - + + - regulation of cell-cell adhesion + The last step in the formation of the neural tube, where the paired neural folds are brought together and fuse at the dorsal midline. + biological_process + GO:0001843 + neural tube closure + + + + The last step in the formation of the neural tube, where the paired neural folds are brought together and fuse at the dorsal midline. + GOC:dph + ISBN:0878932437 + - + - + - + - - + + - - + - - + + - negative regulation of cell-cell adhesion + Combining with a polysaccharide and transmitting the signal to initiate an innate immune response. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. + polysaccharide receptor activity + molecular_function + GO:0001873 + polysaccharide immune receptor activity + + + + Combining with a polysaccharide and transmitting the signal to initiate an innate immune response. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. + PMID:14707091 + - + - + - + - - + + - - + - - + + - positive regulation of cell-cell adhesion - - - - - - - - - + - circadian sleep/wake cycle process + The progression of an endothelial cell over time, from its formation to the mature structure. + biological_process + GO:0001885 + endothelial cell development + + + + The progression of an endothelial cell over time, from its formation to the mature structure. + GOC:dph + - + - + - + - - + + - - + - + - cellular process involved in reproduction in multicellular organism + The change in form (cell shape and size) that occurs during the differentiation of an endothelial cell. + biological_process + GO:0001886 + endothelial cell morphogenesis + + + + The change in form (cell shape and size) that occurs during the differentiation of an endothelial cell. + GOC:ascb_2009 + GOC:dph + GOC:tb + - + - + - + - - + + - + + - + - reproductive process + The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes. + biological_process + GO:0001889 + liver development + + + + The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes. + GOC:add + ISBN:068340007X + - + - + - + - - + + - + + - - + + - digestive system process + + + + + + + The process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin. + placental development + placentation + biological_process + GO:0001890 + placenta development + + + + The process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin. + GOC:add + ISBN:068340007X + + + + + placentation + GOC:dph + GOC:tb + - + - + - + - - + + - - + - + - ovulation cycle process + + + + + + + The embryonically driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin. + fetal placenta development + biological_process + GO:0001892 + embryonic placenta development + + + + The embryonically driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin. + GOC:add + ISBN:068340007X + + + + + fetal placenta development + GOC:dph + - + - + - + - - + + - + + + - - + + - regulation of anatomical structure morphogenesis + Maternally driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin. + biological_process + decidua development + GO:0001893 + maternal placenta development + + + + Maternally driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin. + GOC:add + ISBN:068340007X + + + + + decidua development + GOC:dph + - + - - - biological adhesion + + + + + + + + + + + + + + + The inner segment of a vertebrate photoreceptor containing mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs. + cellular_component + GO:0001917 + + photoreceptor inner segment + + + + The inner segment of a vertebrate photoreceptor containing mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs. + GOC:add + PMID:12019563 + - + - + - + - - + + - - - - - - - - signal transduction involved in regulation of gene expression + Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein. + regulation of protein amino acid phosphorylation + biological_process + GO:0001932 + regulation of protein phosphorylation + + + + Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein. + GOC:hjd + + + + + regulation of protein amino acid phosphorylation + GOC:bf + - + - + - - + + - - - - - - - - regulation of signaling - - - - - - - - - signaling + Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein. + down regulation of protein amino acid phosphorylation + down-regulation of protein amino acid phosphorylation + downregulation of protein amino acid phosphorylation + negative regulation of protein amino acid phosphorylation + inhibition of protein amino acid phosphorylation + biological_process + GO:0001933 + negative regulation of protein phosphorylation + + + + Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein. + GOC:hjd + + + + + negative regulation of protein amino acid phosphorylation + GOC:bf + - + - + - + - - - - - - - - - positive regulation of signaling + Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein. + positive regulation of protein amino acid phosphorylation + up regulation of protein amino acid phosphorylation + up-regulation of protein amino acid phosphorylation + upregulation of protein amino acid phosphorylation + activation of protein amino acid phosphorylation + stimulation of protein amino acid phosphorylation + biological_process + GO:0001934 + positive regulation of protein phosphorylation + + + + Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein. + GOC:hjd + + + + + positive regulation of protein amino acid phosphorylation + GOC:bf + - + - + - + - - + + - - - - - - - - - negative regulation of signaling + + The multiplication or reproduction of endothelial cells, resulting in the expansion of a cell population. Endothelial cells are thin flattened cells which line the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium. + biological_process + GO:0001935 + endothelial cell proliferation + + + + The multiplication or reproduction of endothelial cells, resulting in the expansion of a cell population. Endothelial cells are thin flattened cells which line the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium. + GOC:add + ISBN:0781735149 + - + - + - + - - + + - - - - - - - - signal release - - - - - - - - - myofibril - - - - - - - - - cell junction - - - - - - - - - - peptide hormone secretion - - - - - - - - - - insulin secretion - - - - - - - - - hemopoiesis - - - - - - - - - - lymphocyte differentiation - - - - - - - - - vasopressin secretion + Any process that modulates the frequency, rate, or extent of endothelial cell proliferation. + biological_process + GO:0001936 + regulation of endothelial cell proliferation + + + + Any process that modulates the frequency, rate, or extent of endothelial cell proliferation. + GOC:add + - + - - - water homeostasis + + + + + + + + + + + + + Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation. + down regulation of endothelial cell proliferation + down-regulation of endothelial cell proliferation + downregulation of endothelial cell proliferation + inhibition of endothelial cell proliferation + biological_process + GO:0001937 + negative regulation of endothelial cell proliferation + + + + Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation. + GOC:add + - + - - - cell differentiation + + + + + + + + + + + + + Any process that activates or increases the rate or extent of endothelial cell proliferation. + up regulation of endothelial cell proliferation + up-regulation of endothelial cell proliferation + upregulation of endothelial cell proliferation + activation of endothelial cell proliferation + stimulation of endothelial cell proliferation + biological_process + GO:0001938 + positive regulation of endothelial cell proliferation + + + + Any process that activates or increases the rate or extent of endothelial cell proliferation. + GOC:add + - + - + - + - - + + - + - - + + - regulation of cell adhesion - - - - - - - - - - B cell differentiation - - - - - - - - - - - melatonin metabolic process - - - - - - - - - - - - melatonin biosynthetic process + The process whose specific outcome is the progression of the hair follicle over time, from its formation to the mature structure. A hair follicle is a tube-like opening in the epidermis where the hair shaft develops and into which the sebaceous glands open. + GO:0001943 + biological_process + GO:0001942 + hair follicle development + + + + The process whose specific outcome is the progression of the hair follicle over time, from its formation to the mature structure. A hair follicle is a tube-like opening in the epidermis where the hair shaft develops and into which the sebaceous glands open. + GOC:dph + UBERON:0002073 + - + - + - + - - + + - - - - + - - + + - regulation of blood coagulation + The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism. + biological_process + vascular system development + GO:0001944 + vasculature development + + + + The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism. + GOC:dph + UBERON:0002409 + - + - + - + - - + + - - - - + + - - + + - positive regulation of blood coagulation + The process whose specific outcome is the progression of a lymph vessel over time, from its formation to the mature structure. + biological_process + GO:0001945 + lymph vessel development + + + + The process whose specific outcome is the progression of a lymph vessel over time, from its formation to the mature structure. + GOC:dph + UBERON:0001473 + - + - + - + - - + + - - - - + + - - + + - negative regulation of blood coagulation + Lymph vessel formation when new vessels emerge from the proliferation of pre-existing vessels. + Wikipedia:Lymphangiogenesis + lymph vessel formation + biological_process + GO:0001946 + lymphangiogenesis + + + + Lymph vessel formation when new vessels emerge from the proliferation of pre-existing vessels. + GOC:dph + PMID:11596157 + + + + + lymph vessel formation + + - + - - - - extracellular matrix organization + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for a blood vessel to attain its fully functional state. + biological_process + GO:0001955 + blood vessel maturation + + + + A developmental process, independent of morphogenetic (shape) change, that is required for a blood vessel to attain its fully functional state. + GOC:dph + - + - - - glycosaminoglycan metabolic process + + + Direct ossification that occurs within mesenchyme or an accumulation of relatively unspecialized cells. + Wikipedia:Intramembranous_ossification + dermal ossification + biological_process + intramembranous bone ossification + GO:0001957 + An instance of intramembranous ossification may also be classified as metaplastic; the former classifies based on tissue type location, and the latter based on mechanism/cell division. + intramembranous ossification + + + + Direct ossification that occurs within mesenchyme or an accumulation of relatively unspecialized cells. + ISBN:0878932437 + + + + + dermal ossification + GO_REF:0000034 + + + + + intramembranous bone ossification + GOC:cjm + - + - - + + - + - keratinocyte differentiation - - - - - - - - - - T cell differentiation + Replacement ossification wherein bone tissue replaces cartilage. + Wikipedia:Endochondral_ossification + biological_process + GO:0001958 + endochondral ossification + + + + Replacement ossification wherein bone tissue replaces cartilage. + GO_REF:0000034 + ISBN:0878932437 + - + - + - + - - + + - + The regulation of blood pressure mediated by detection of stimuli and a neurological response. + blood pressure regulation by neurological process + neurological process involved in regulation of systemic arterial blood pressure + neurological system process involved in regulation of systemic arterial blood pressure + biological_process + fast control of arterial pressure + GO:0001976 + nervous system process involved in regulation of systemic arterial blood pressure + + + + + The regulation of blood pressure mediated by detection of stimuli and a neurological response. + GOC:mtg_cardio + ISBN:0721643949 + + + + + neurological process involved in regulation of systemic arterial blood pressure + GOC:dph + GOC:tb + + + + + + + + - - + + - regulation of ossification + A slow mechanism of blood pressure regulation that responds to changes in pressure resulting from fluid and salt intake by modulating the quantity of blood in the circulatory system. + biological_process + renal blood volume control of blood pressure + renal regulation of blood volume + GO:0001977 + renal system process involved in regulation of blood volume + + + + A slow mechanism of blood pressure regulation that responds to changes in pressure resulting from fluid and salt intake by modulating the quantity of blood in the circulatory system. + GOC:dph + GOC:tb + ISBN:0721643949 + + + + + renal regulation of blood volume + GOC:dph + GOC:tb + - + - - - - - - - - - - - - - - + + - - + + - negative regulation of ossification + The process that modulates blood pressure by sensing the amount of stretch occurring in large arteries and responding to the input via central nervous system control. + carotid sinus baroreceptor feedback regulation of systemic arterial blood pressure + biological_process + baroreceptor feedback control of blood pressure + baroreceptor pressure buffer system + GO:0001978 + regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback + + + + The process that modulates blood pressure by sensing the amount of stretch occurring in large arteries and responding to the input via central nervous system control. + GOC:dph + GOC:tb + ISBN:0721643949 + + + + + carotid sinus baroreceptor feedback regulation of systemic arterial blood pressure + GOC:dph + GOC:tb + + + + + baroreceptor pressure buffer system + ISBN:068340007X + - + - - + + + The process that modulates blood pressure by the action of chemoreceptors found in the carotid and aortic bodies and their resultant modulation of the vasomotor center. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions. + chemoreceptor regulation of systemic arterial blood pressure + regulation of systemic arterial blood pressure by chemoreceptor signalling + biological_process + chemoreceptor control of blood pressure + GO:0001979 + regulation of systemic arterial blood pressure by chemoreceptor signaling + + + + + The process that modulates blood pressure by the action of chemoreceptors found in the carotid and aortic bodies and their resultant modulation of the vasomotor center. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions. + GOC:dph + GOC:tb + ISBN:0721643949 + + + + + chemoreceptor regulation of systemic arterial blood pressure + GOC:dph + GOC:tb + + + + + regulation of systemic arterial blood pressure by chemoreceptor signalling + GOC:mah + + + + + + + + + + The process in which hormones modulate the force with which blood passes through the circulatory system. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action. + blood pressure regulation by hormone + hormonal regulation of blood pressure + biological_process + hormonal control of blood pressure + GO:0001990 + regulation of systemic arterial blood pressure by hormone + + + + + The process in which hormones modulate the force with which blood passes through the circulatory system. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action. + GOC:mtg_cardio + ISBN:0721643949 + + + + + + + + + The regulation of blood pressure mediated by the signaling molecule vasopressin. Vasopressin is produced in the hypothalamus, and affects vasoconstriction, and renal water transport. + blood pressure regulation by vasopressin + biological_process + vasopressin control of blood pressure + GO:0001992 + regulation of systemic arterial blood pressure by vasopressin + + + + + The regulation of blood pressure mediated by the signaling molecule vasopressin. Vasopressin is produced in the hypothalamus, and affects vasoconstriction, and renal water transport. + GOC:mtg_cardio + ISBN:0721643949 + + + + + + + + - + - bone mineralization + + + + + + + + + + + + + The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies. + detection of hypoxic conditions in blood by chemoreceptor signalling + biological_process + GO:0002007 + detection of hypoxic conditions in blood by chemoreceptor signaling + + + + The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies. + GOC:dph + + + + + detection of hypoxic conditions in blood by chemoreceptor signalling + GOC:mah + - + - + - + - - + + - - - + - - + + - positive regulation of cell growth + The process in which the anatomical structures of epithelia are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube. + epithelium morphogenesis + biological_process + GO:0002009 + morphogenesis of an epithelium + + + + The process in which the anatomical structures of epithelia are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube. + GOC:dph + GOC:jl + GOC:tb + ISBN:0198506732 + - + - + - + - - + + - - - - - - - - - - negative regulation of cell growth - - - - - - - - - - - - - - - external encapsulating structure + + The process in which the anatomical structures of an epithelial sheet are generated and organized. An epithelial sheet is a flat surface consisting of closely packed epithelial cells. + biological_process + GO:0002011 + morphogenesis of an epithelial sheet + + + + The process in which the anatomical structures of an epithelial sheet are generated and organized. An epithelial sheet is a flat surface consisting of closely packed epithelial cells. + GOC:jl + - + - - - - - flagellated sperm motility + + + The process in which the renin-angiotensin system controls the rate of fluid intake and output into the blood. + renin-angiotensin regulation of blood volume + biological_process + renin-angiotensin control of body fluid levels + GO:0002016 + regulation of blood volume by renin-angiotensin + + + + The process in which the renin-angiotensin system controls the rate of fluid intake and output into the blood. + GOC:dph + GOC:mtg_cardio + GOC:tb + ISBN:0721643949 + + + + + renin-angiotensin regulation of blood volume + GOC:dph + GOC:tb + - + - + - + + + + + - + - + + + + + + + + - + - regulation of cell migration + The process in which an increase in active angiotensin stimulates the adrenal cortices to secrete aldosterone. + biological_process + renin-angiotensin control of aldosterone production + GO:0002018 + renin-angiotensin regulation of aldosterone production + + + + The process in which an increase in active angiotensin stimulates the adrenal cortices to secrete aldosterone. + ISBN:0721643949 + - + - + - - + + - - - - - - - - - positive regulation of cell migration + + Any process that modulates the frequency or rate of heart contraction. + cardiac chronotropy + regulation of heart contraction rate + regulation of rate of heart contraction + biological_process + GO:0002027 + regulation of heart rate + + + + Any process that modulates the frequency or rate of heart contraction. + GOC:dph + GOC:tb + PMID:10358008 + + + + + cardiac chronotropy + GOC:dph + GOC:tb + - + - + - - + + - - - - - - - - - negative regulation of cell migration - - - - - - - - - defecation - - - - - - - - - axon - - - - - - - - - - - - - - - dendrite - - - - - - - - - sleep - - - - - - - - - peristalsis + Any process that modulates the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + regulation of Na+ transport + regulation of sodium transport + biological_process + GO:0002028 + regulation of sodium ion transport + + + + Any process that modulates the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:dph + - + - + - - + + - - - - - - - - - regulation of bone mineralization + + Any process that activates or increases the rate of neuroblast proliferation. + up regulation of neuroblast proliferation + up-regulation of neuroblast proliferation + upregulation of neuroblast proliferation + activation of neuroblast proliferation + stimulation of neuroblast proliferation + biological_process + GO:0002052 + positive regulation of neuroblast proliferation + + + + Any process that activates or increases the rate of neuroblast proliferation. + GOC:dph + - + - + - + - - - - - - - - - - positive regulation of bone mineralization + + + The process of activating or increasing the rate or extent of mesenchymal cell proliferation. Mesenchymal cells are loosely organized embryonic cells. + up regulation of mesenchymal cell proliferation + up-regulation of mesenchymal cell proliferation + upregulation of mesenchymal cell proliferation + activation of mesenchymal cell proliferation + stimulation of mesenchymal cell proliferation + biological_process + GO:0002053 + positive regulation of mesenchymal cell proliferation + + + + The process of activating or increasing the rate or extent of mesenchymal cell proliferation. Mesenchymal cells are loosely organized embryonic cells. + GOC:dph + - + - + - + - - + + - - - + - - + + - negative regulation of bone mineralization + The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte. A chondrocyte is a polymorphic cell that forms cartilage. + biological_process + GO:0002062 + chondrocyte differentiation + + + + The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte. A chondrocyte is a polymorphic cell that forms cartilage. + GOC:dph + - + - + - + - - + + - - - - - - - - cytoplasmic vesicle membrane - - - - - - - - + - + - epithelial cell differentiation + The process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate. + biological_process + GO:0002063 + chondrocyte development + + + + The process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate. + GOC:dph + - + - + - + - - + + - - + - + - regulation of epithelial cell differentiation + The process whose specific outcome is the progression of an epithelial cell over time, from its formation to the mature structure. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface. + biological_process + GO:0002064 + epithelial cell development + + + + The process whose specific outcome is the progression of an epithelial cell over time, from its formation to the mature structure. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface. + GOC:dph + - + - + - + - - + + - - - - - - - - - negative regulation of epithelial cell differentiation + + The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube. + biological_process + GO:0002065 + columnar/cuboidal epithelial cell differentiation + + + + The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube. + GOC:dph + - + - + - + - - + + - - + - - + + - positive regulation of epithelial cell differentiation - - - - - - - - - mammary gland development + The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell over time, from its formation to the mature structure. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube. + biological_process + GO:0002066 + columnar/cuboidal epithelial cell development + + + + The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell over time, from its formation to the mature structure. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube. + GOC:dph + - + - + - + - - + + - - - - - - - - - regulation of B cell proliferation + + The process in which a relatively unspecialized cell acquires specialized features of a glandular epithelial cell. A glandular epithelial cell is a columnar/cuboidal epithelial cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland. + biological_process + GO:0002067 + glandular epithelial cell differentiation + + + + The process in which a relatively unspecialized cell acquires specialized features of a glandular epithelial cell. A glandular epithelial cell is a columnar/cuboidal epithelial cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland. + GOC:dph + - + - + - + - - + + - - - + - - + + - negative regulation of B cell proliferation + The process whose specific outcome is the progression of a glandular epithelial cell over time, from its formation to the mature structure. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland. + biological_process + GO:0002068 + glandular epithelial cell development + + + + The process whose specific outcome is the progression of a glandular epithelial cell over time, from its formation to the mature structure. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland. + GOC:dph + - + - + - + - - + + - - - + - - + + - positive regulation of B cell proliferation - - - - - - - - - intraciliary transport particle - - - - - - - - - extracellular matrix + The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell to attain its fully functional state. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube. + biological_process + GO:0002069 + columnar/cuboidal epithelial cell maturation + + + + The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell to attain its fully functional state. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube. + GOC:dph + - + - + - + - - + + - - - - - - - - organelle membrane - - - - - - - - - regeneration - - - - - - - - - + - + - biomineral tissue development + The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface. + biological_process + GO:0002070 + epithelial cell maturation + + + + The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface. + GOC:dph + - + - + - + - - + + - - + - - + + - regulation of cellular metabolic process + The developmental process, independent of morphogenetic (shape) change, that is required for a glandular epithelial cell to attain its fully functional state. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland. + biological_process + GO:0002071 + glandular epithelial cell maturation + + + + The developmental process, independent of morphogenetic (shape) change, that is required for a glandular epithelial cell to attain its fully functional state. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland. + GOC:dph + - + - + - + - - + + - - - + - - + + - negative regulation of cellular metabolic process + The invagination of the optic vesicle to form two-walled indentations, the optic cups, that will go on to form the retina. This process begins with the optic vesicle becoming a two-walled structure and its subsequent shape changes. It does not include the fate commitment of cells to become the pigmented retina and the neural retina. An example of this process is found in Mus musculus. + optic cup morphogenesis involved in camera-style eye development + biological_process + GO:0002072 + optic cup morphogenesis involved in camera-type eye development + + + + The invagination of the optic vesicle to form two-walled indentations, the optic cups, that will go on to form the retina. This process begins with the optic vesicle becoming a two-walled structure and its subsequent shape changes. It does not include the fate commitment of cells to become the pigmented retina and the neural retina. An example of this process is found in Mus musculus. + GOC:dph + GOC:mtg_sensu + GOC:sdb_2009 + GOC:tb + ISBN:0878932437 + - + - + - + - - + + - - - + - - + + - positive regulation of cellular metabolic process + The process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. An example of this process is found in Mus musculus. + biological_process + GO:0002074 + extraocular skeletal muscle development + + + + The process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. An example of this process is found in Mus musculus. + GOC:dph + GOC:mtg_muscle + GOC:mtg_sensu + MA:0001271 + PMID:16638982 + - + - + - + - - + + - - - - - - - - - regulation of cellular biosynthetic process + The process whose specific outcome is the progression of the somitomeric trunk muscle over time, from its formation to the mature structure. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. An example of this process is found in Mus musculus. + biological_process + GO:0002075 + somitomeric trunk muscle development + + + + The process whose specific outcome is the progression of the somitomeric trunk muscle over time, from its formation to the mature structure. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. An example of this process is found in Mus musculus. + GOC:dph + PMID:16638982 + - + - + - + - - + + - - - + - - + + - negative regulation of cellular biosynthetic process + The process whose specific outcome is the progression of an osteoblast over time, from its formation to the mature structure. Osteoblast development does not include the steps involved in committing a cranial neural crest cell or an osteoprogenitor cell to an osteoblast fate. An osteoblast is a cell that gives rise to bone. + biological_process + GO:0002076 + osteoblast development + + + + The process whose specific outcome is the progression of an osteoblast over time, from its formation to the mature structure. Osteoblast development does not include the steps involved in committing a cranial neural crest cell or an osteoprogenitor cell to an osteoblast fate. An osteoblast is a cell that gives rise to bone. + GOC:dph + - + - + - + - - + + - - - - - - - - - - positive regulation of cellular biosynthetic process + + A process carried out by the nervous system that is required for the proper control of respiratory gaseous exchange. This process occurs in the respiratory center of the brain in vertebrates. + neurological control of breathing + regulation of respiratory gaseous exchange by neurological system process + biological_process + GO:0002087 + regulation of respiratory gaseous exchange by nervous system process + + + + A process carried out by the nervous system that is required for the proper control of respiratory gaseous exchange. This process occurs in the respiratory center of the brain in vertebrates. + GOC:dph + GOC:tb + PMID:12458206 + + + + + neurological control of breathing + GOC:dph + GOC:tb + - + - + - + - - + + - - + + - - + + - regulation of cellular catabolic process + The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus. + lens development + lens development in camera-style eye + biological_process + GO:0002088 + lens development in camera-type eye + + + + The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus. + GOC:dph + ISBN:0582064333 + - + - + - + - - + + - - - + + - - + + - negative regulation of cellular catabolic process + + + + + + + The process in which the anatomical structures of the lens are generated and organized. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus. + lens morphogenesis + lens morphogenesis in camera-style eye + biological_process + GO:0002089 + lens morphogenesis in camera-type eye + + + + The process in which the anatomical structures of the lens are generated and organized. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus. + GOC:dph + GOC:mtg_sensu + - + - + - + - - + + - - - + + - - + + - positive regulation of cellular catabolic process + + + + + + + Any process that alters the size or shape of an auditory receptor cell. + hair cell morphogenesis + biological_process + GO:0002093 + auditory receptor cell morphogenesis + + + + Any process that alters the size or shape of an auditory receptor cell. + GOC:dph + GOC:tb + + + + + hair cell morphogenesis + GO:dph + - + - + + + The process whose specific outcome is the progression of the amphibian larva over time, from its formation to the mature structure. Amphibian larvae, sometimes called pollywogs or tadpoles, hatch from eggs and begin to grow limbs and other adult physical features at various times, depending on the species, before they metamorphose into the adult form. + biological_process + GO:0002117 + amphibian larval development + + + + + The process whose specific outcome is the progression of the amphibian larva over time, from its formation to the mature structure. Amphibian larvae, sometimes called pollywogs or tadpoles, hatch from eggs and begin to grow limbs and other adult physical features at various times, depending on the species, before they metamorphose into the adult form. + GOC:bf + PMID:27143402 + + + + + + + - + - - + + - - + - - + + - regulation of vesicle fusion + + + + + + + The process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew. + biological_process + GO:0002119 + nematode larval development + + + + The process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew. + GOC:ems + GOC:kmv + - + - - - - - - - - - - - - - - - + + + + The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. The larva is the early, immature form of an that at birth or hatching is fundamentally unlike its parent and must metamorphose before assuming the adult characters. + biological_process + GO:0002164 + larval development + + + + + The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. The larva is the early, immature form of an that at birth or hatching is fundamentally unlike its parent and must metamorphose before assuming the adult characters. + GOC:jid + ISBN:0877795088 + + + + + + + + + - - + + - negative regulation of vesicle fusion + + + + + + + The process whose specific outcome is the progression of the instar larva or pupa over time, from its formation to the mature structure. An example of this process is found in Drosophila melanogaster. + biological_process + GO:0002165 + instar larval or pupal development + + + + The process whose specific outcome is the progression of the instar larva or pupa over time, from its formation to the mature structure. An example of this process is found in Drosophila melanogaster. + GOC:jid + GOC:mtg_sensu + - + - + + + + The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. This begins with the newly hatched first-instar larva, through its maturation to the end of the last larval stage. An example of this process is found in Drosophila melanogaster. + biological_process + GO:0002168 + instar larval development + + + + + The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. This begins with the newly hatched first-instar larva, through its maturation to the end of the last larval stage. An example of this process is found in Drosophila melanogaster. + GOC:bf + GOC:mtg_sensu + + + + + + + - + - - + + - - - - - - - - - - positive regulation of vesicle fusion + A response to protect an organism from a directly detected or perceived external threat from an insect or insects to that organism. + GO:0002214 + physiological defense response to insect + biological_process + GO:0002213 + defense response to insect + + + + A response to protect an organism from a directly detected or perceived external threat from an insect or insects to that organism. + GOC:add + - + - + - + - - + + - - - - - - - - regulation of defense response + A response to protect an organism from a directly detected or perceived external threat from a nematode or nematodes, which results in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack. + GO:0002216 + physiological defense response to nematode + biological_process + GO:0002215 + defense response to nematode + + + + A response to protect an organism from a directly detected or perceived external threat from a nematode or nematodes, which results in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack. + GOC:add + PMID:11516579 + PMID:14506883 + - + - + - + - - + + - - + - - + + - negative regulation of defense response + The series of events that restore integrity to damaged tissue that contribute to an inflammatory response. + biological_process + healing during inflammatory response + inflammatory response wound healing + GO:0002246 + wound healing involved in inflammatory response - - - - - - - - - - - - - - - - - - - + + + + The series of events that restore integrity to damaged tissue that contribute to an inflammatory response. + GOC:jal + ISBN:0721601871 + + + + + healing during inflammatory response + GOC:dph + + + + + inflammatory response wound healing + GOC:dph + + + + + + + + - - + + - positive regulation of defense response - - - - - - - - - - - - - - - - - - - - - + + - cytoplasmic vesicle + An immune response mediated by cells expressing specific receptors for antigen produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory). + Wikipedia:Adaptive_immune_system + acquired immune response + immune memory response + biological_process + GO:0002250 + adaptive immune response + + + + An immune response mediated by cells expressing specific receptors for antigen produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory). + GOC:add + GO_REF:0000022 + ISBN:0781735149 + + + + + acquired immune response + ISBN:068340007X + + + + + immune memory response + GOC:add + - + - - - regulation of buoyancy + + + An immune response taking place in an organ or tissues such as the liver, brain, mucosa, or nervous system tissues. + immune response in organ or tissue + biological_process + GO:0002251 + organ or tissue specific immune response + + + + An immune response taking place in an organ or tissues such as the liver, brain, mucosa, or nervous system tissues. + GOC:jal + GO_REF:0000022 + - + - - - - - - - - - keratinization + + + Any process of the immune system that executes a component of an immune response. An effector immune process takes place after its activation. + https://github.com/geneontology/go-ontology/issues/18737 + biological_process + GO:0002252 + immune effector process + + + + Any process of the immune system that executes a component of an immune response. An effector immune process takes place after its activation. + GOC:add + GO_REF:0000022 + ISBN:0781735149 + - + - + - + - - + + - - - - - - - - regulation of nervous system process + + The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus. + biological_process + GO:0002260 + lymphocyte homeostasis + + + + The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus. + GOC:add + PMID:15826826 + PMID:16319493 + PMID:16551252 + PMID:16551262 + - + - + - + - - + + - - - - - - - - - negative regulation of nervous system process + + + The process of regulating the proliferation and elimination of myeloid cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. + biological_process + GO:0002262 + myeloid cell homeostasis + + + + The process of regulating the proliferation and elimination of myeloid cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. + CL:0000763 + GOC:add + - + - + - + - - + + - - - - - - - - - positive regulation of nervous system process + + + A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response. + biological_process + cell activation during immune response + GO:0002263 + cell activation involved in immune response + + + + A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response. + GOC:add + GO_REF:0000022 + ISBN:0781735149 + + + + + cell activation during immune response + GOC:tb + - + - + - + - - + + - - - - - - - - - - regulation of glucocorticoid metabolic process + A change in the morphology or behavior of an endothelial cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response. + biological_process + endothelial cell activation during immune response + GO:0002264 + endothelial cell activation involved in immune response + + + + A change in the morphology or behavior of an endothelial cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response. + GOC:add + ISBN:0781735149 + + + + + endothelial cell activation during immune response + GOC:tb + - + - + - + - - + + - - - - - - - - - - - negative regulation of glucocorticoid metabolic process + A change in the morphology or behavior of an astrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response. + biological_process + astrocyte activation during immune response + GO:0002265 + astrocyte activation involved in immune response + + + + A change in the morphology or behavior of an astrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response. + GOC:add + PMID:11138785 + + + + + astrocyte activation during immune response + GOC:tb + - + - + - + - - + + - - - - - - - - - - - positive regulation of glucocorticoid metabolic process + + A change in the morphology or behavior of a leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an inflammatory response. + biological_process + immune cell activation during inflammatory response + leukocyte activation during inflammatory response + GO:0002269 + leukocyte activation involved in inflammatory response + + + + A change in the morphology or behavior of a leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an inflammatory response. + GOC:add + ISBN:0781735149 + + + + + leukocyte activation during inflammatory response + GOC:tb + - + - + - + - - + + - - - - - - - - - regulation of glucocorticoid biosynthetic process + + A change in the morphology or behavior of a myeloid leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. + myeloid leucocyte activation + biological_process + GO:0002274 + myeloid leukocyte activation + + + + A change in the morphology or behavior of a myeloid leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. + GOC:add + ISBN:0781735149 + - + - + + + + A change in the morphology or behavior of a myeloid cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response. + biological_process + myeloid cell activation during immune response + GO:0002275 + myeloid cell activation involved in immune response + + + + + A change in the morphology or behavior of a myeloid cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response. + GOC:add + ISBN:0781735149 + + + + + myeloid cell activation during immune response + GOC:tb + + + + + + + - + - - + + - - - - - - - - - - negative regulation of glucocorticoid biosynthetic process + + The change in morphology and behavior of a myeloid dendritic cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. + biological_process + myeloid dendritic cell activation during immune response + GO:0002277 + myeloid dendritic cell activation involved in immune response + + + + The change in morphology and behavior of a myeloid dendritic cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. + GOC:add + ISBN:0781735149 + + + + + myeloid dendritic cell activation during immune response + GOC:tb + - + - + - + - - + + - - - - - - - - - - positive regulation of glucocorticoid biosynthetic process + + A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. + macrophage polarization involved in immune response + biological_process + macrophage activation during immune response + GO:0002281 + macrophage activation involved in immune response + + + + A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. + GOC:add + ISBN:0781735149 + + + + + macrophage activation during immune response + GOC:tb + - + - + - + - + - - - - - - - - nuclear membrane - - - - - - - - - - - - - - - - - - - - - organelle envelope + The process in which an immature myeloid dendritic cell acquires the specialized features of a mature myeloid dendritic cell as part of an immune response. + biological_process + myeloid dendritic cell differentiation during immune response + GO:0002284 + myeloid dendritic cell differentiation involved in immune response + + + + The process in which an immature myeloid dendritic cell acquires the specialized features of a mature myeloid dendritic cell as part of an immune response. + GOC:add + ISBN:0781735149 + + + + + myeloid dendritic cell differentiation during immune response + GOC:tb + - + - - - envelope + + + + + + + + + + + + + + + A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. + biological_process + lymphocyte activation during immune response + GO:0002285 + lymphocyte activation involved in immune response + + + + A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. + GOC:add + ISBN:0781735149 + + + + + lymphocyte activation during immune response + GOC:tb + - + - - - vesicle + + + + + + + + + + + + + + + The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response. + biological_process + T cell activation during immune response + T lymphocyte activation during immune response + T-cell activation during immune response + T-lymphocyte activation during immune response + GO:0002286 + T cell activation involved in immune response + + + + The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response. + GOC:add + ISBN:0781735149 + + + + + T cell activation during immune response + GOC:tb + - + - + - + - + - - - - - - - - locomotion involved in locomotory behavior + + + The process in which an antigenically naive T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells. + biological_process + T cell development involved in immune response + T cell differentiation during immune response + T lymphocyte differentiation during immune response + T-cell differentiation during immune response + T-lymphocyte differentiation during immune response + GO:0002292 + Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. + T cell differentiation involved in immune response + + + + The process in which an antigenically naive T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells. + GOC:add + ISBN:0781735149 + + + + + T cell development involved in immune response + GOC:add + + + + + T cell differentiation during immune response + GOC:tb + - + - + - + - - + + - - - - - - - - - - positive regulation of insulin secretion + The expansion of a T cell population by cell division as part of an immune response. + biological_process + T cell proliferation during immune response + T lymphocyte proliferation during immune response + T-cell proliferation during immune response + T-lymphocyte proliferation during immune response + GO:0002309 + T cell proliferation involved in immune response + + + + The expansion of a T cell population by cell division as part of an immune response. + GOC:add + ISBN:0781735149 + + + + + T cell proliferation during immune response + GOC:tb + - + - + - + - - + + - - - - - - - - regulation of response to external stimulus + + + The change in morphology and behavior of a mature or immature B cell during an immune response, resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. + biological_process + B cell activation during immune response + B lymphocyte activation during immune response + B-cell activation during immune response + B-lymphocyte activation during immune response + GO:0002312 + B cell activation involved in immune response + + + + The change in morphology and behavior of a mature or immature B cell during an immune response, resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. + GOC:jal + + + + + B cell activation during immune response + GOC:tb + - + - + - + - - + + - - - - - - - - - negative regulation of response to external stimulus + + + The process in which a naive B cell acquires the specialized features of a mature or memory B cell during an immune response. + biological_process + mature B cell development involved in immune response + mature B cell differentiation during immune response + mature B lymphocyte differentiation during immune response + mature B-cell differentiation during immune response + mature B-lymphocyte differentiation during immune response + GO:0002313 + Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. + mature B cell differentiation involved in immune response + + + + The process in which a naive B cell acquires the specialized features of a mature or memory B cell during an immune response. + GOC:jal + + + + + mature B cell development involved in immune response + GOC:add + + + + + mature B cell differentiation during immune response + GOC:tb + - + - + - + - - + + - - - - - - - - - positive regulation of response to external stimulus + + The process in which a B cell acquires the specialized features of a plasma cell. A plasma cell is a lymphocyte which develops from a B cell and produces high amounts of antibody. + biological_process + plasma cell development + GO:0002317 + Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. + plasma cell differentiation + + + + The process in which a B cell acquires the specialized features of a plasma cell. A plasma cell is a lymphocyte which develops from a B cell and produces high amounts of antibody. + GOC:jal + + + + + plasma cell development + GOC:add + - + - + - + - - + + - - - - - - - - - regulation of chondrocyte differentiation + + + The process in which a B cell acquires the specialized features of a memory B cell. Memory B cells are cells that can respond rapidly to antigen re-exposure by production of high-affinity antibody. + memory B lymphocyte differentiation + memory B-cell differentiation + memory B-lymphocyte differentiation + biological_process + memory B cell development + GO:0002319 + Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. + memory B cell differentiation + + + + The process in which a B cell acquires the specialized features of a memory B cell. Memory B cells are cells that can respond rapidly to antigen re-exposure by production of high-affinity antibody. + GOC:jal + ISBN:0781735149 + + + + + memory B cell development + GOC:add + - + - + - + - - + + - - - - - - - - - - negative regulation of chondrocyte differentiation + + + The expansion of a B cell population by cell division following B cell activation during an immune response. + biological_process + B cell proliferation during immune response + B lymphocyte proliferation during immune response + B-cell proliferation during immune response + B-lymphocyte proliferation during immune response + GO:0002322 + B cell proliferation involved in immune response + + + + The expansion of a B cell population by cell division following B cell activation during an immune response. + GOC:jal + + + + + B cell proliferation during immune response + GOC:tb + - + - + - + - - + + - - - - - - - - - - positive regulation of chondrocyte differentiation + + The process in which transitional stage B cells acquire the specialized features of mature B cells in the spleen. + mature B lymphocyte differentiation + mature B-cell differentiation + mature B-lymphocyte differentiation + biological_process + mature cell development + GO:0002335 + Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. + mature B cell differentiation + + + + The process in which transitional stage B cells acquire the specialized features of mature B cells in the spleen. + GOC:jal + ISBN:0781735149 + + + + + mature cell development + GOC:add + - + - - - - - - - - aldosterone metabolic process + + + The synthesis or release of histamine following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels. + histamine production involved in acute inflammatory response + biological_process + GO:0002349 + histamine production involved in inflammatory response + + + + The synthesis or release of histamine following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels. + GOC:add + ISBN:0781735149 + PMID:16730260 + - + - - - - - - - - - aldosterone biosynthetic process + + + The synthesis or release of serotonin following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels. + serotonin production involved in acute inflammatory response + biological_process + GO:0002351 + serotonin production involved in inflammatory response + + + + The synthesis or release of serotonin following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels. + GOC:add + ISBN:0781735149 + PMID:16730260 + - + - + - + - - + + + + + + - - - - - - - - - - regulation of aldosterone metabolic process + + The non-specific expansion of B cell populations within a whole or part of an organism to reach to a total number of B cells which will then remain stable over time in the absence of an external stimulus. + B lymphocyte homeostatic proliferation + B-cell homeostatic proliferation + B-lymphocyte homeostatic proliferation + biological_process + GO:0002358 + B cell homeostatic proliferation + + + + The non-specific expansion of B cell populations within a whole or part of an organism to reach to a total number of B cells which will then remain stable over time in the absence of an external stimulus. + GOC:jal + - + - + - + - - + + - - - - - - - - - - - - negative regulation of aldosterone metabolic process + + + A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. + biological_process + immune cell activation during immune response + leucocyte activation during immune response + leukocyte activation during immune response + GO:0002366 + leukocyte activation involved in immune response + + + + A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response. + GOC:add + ISBN:0781735149 + + + + + leukocyte activation during immune response + GOC:tb + - + - - + + + - - + - - + + - + - - - - - - + - - + + + + + + - positive regulation of aldosterone metabolic process + + + + + + + + Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats. + + Wikipedia:Immune_system + biological_process + GO:0002376 + + + + + + + Note that this term is a direct child of 'biological_process ; GO:0008150' because some immune system processes are types of cellular process (GO:0009987), whereas others are types of multicellular organism process (GO:0032501). + immune system process + + + + Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats. + GOC:add + GO_REF:0000022 + - + - + + + The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. + GO:0002378 + GO:0048305 + antibody production + immunoglobulin biosynthetic process + immunoglobulin secretion + biological_process + GO:0002377 + + Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms. + immunoglobulin production + + + + + The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. + GOC:add + ISBN:0781735149 + + + + + + + - + - - + + - - - - + - - + + - regulation of aldosterone biosynthetic process + + + + + + + An immune response taking place in the liver. + biological_process + GO:0002384 + hepatic immune response + + + + An immune response taking place in the liver. + GOC:jal + GO_REF:0000022 + ISBN:0781735149 + - + - + - + - - + + - - - - - - - - - - - negative regulation of aldosterone biosynthetic process + Immune response taking place in the gut-associated lymphoid tissue (GALT). GALT includes Peyer's patches, appendix, and solitary lymph nodules. + immune response in GALT + biological_process + GO:0002387 + immune response in gut-associated lymphoid tissue + + + + Immune response taking place in the gut-associated lymphoid tissue (GALT). GALT includes Peyer's patches, appendix, and solitary lymph nodules. + GOC:jal + ISBN:0781735149 + - + - + - + - - + + - - - - + - - + + - positive regulation of aldosterone biosynthetic process + + + + + + + Immune response taking place in the Peyer's patch, nodular lymphoid structures on the serosal surface of the small intestine. + biological_process + GO:0002388 + immune response in Peyer's patch + + + + Immune response taking place in the Peyer's patch, nodular lymphoid structures on the serosal surface of the small intestine. + GOC:jal + ISBN:0781735149 + - + - + - + - - + + - - - - - - - - - regulation of hormone metabolic process + An immune response taking place in the nasopharyngeal-associated lymphoid tissue (NALT). NALT includes the tonsils and adenoids. + immune response in NALT + biological_process + GO:0002395 + immune response in nasopharyngeal-associated lymphoid tissue + + + + An immune response taking place in the nasopharyngeal-associated lymphoid tissue (NALT). NALT includes the tonsils and adenoids. + GOC:jal + ISBN:0781735149 + - + - + + + + The synthesis or release of any molecular mediator of the immune response, resulting in an increase in its intracellular or extracellular levels. + biological_process + production of cellular mediator of immune response + GO:0002440 + + Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select one of the 'regulation' children terms. + production of molecular mediator of immune response + + + + + The synthesis or release of any molecular mediator of the immune response, resulting in an increase in its intracellular or extracellular levels. + GOC:add + GO_REF:0000022 + ISBN:0781735149 + + + + + + + - + - - + + - - + - - + + - negative regulation of hormone metabolic process + The regulated release of histamine by a cell as part of an inflammatory response. + histamine secretion involved in acute inflammatory response + biological_process + GO:0002441 + histamine secretion involved in inflammatory response + + + + The regulated release of histamine by a cell as part of an inflammatory response. + GOC:add + ISBN:0781735149 + - + - + - + - - + + - - + - - + + - positive regulation of hormone metabolic process + The regulated release of serotonin by a cell as part of an inflammatory response. + serotonin secretion involved in acute inflammatory response + biological_process + serotonin release involved in inflammatory response + GO:0002442 + serotonin secretion involved in inflammatory response + + + + The regulated release of serotonin by a cell as part of an inflammatory response. + GOC:add + ISBN:0781735149 + + + + + serotonin release involved in inflammatory response + GOC:tb + - + - + - + - - + + - - - - - - - - - - negative regulation of hormone biosynthetic process + + Any process involved in the carrying out of an immune response by a leukocyte. + GO:0019723 + GO:0042087 + immune cell effector process + immune cell mediated immunity + leucocyte immune effector process + leucocyte mediated immunity + leukocyte immune effector process + biological_process + cell-mediated immune response + cellular immune response + GO:0002443 + leukocyte mediated immunity + + + + Any process involved in the carrying out of an immune response by a leukocyte. + GOC:add + GO_REF:0000022 + ISBN:0781735149 + - + - + - + - - + + - - - - - - - - - regulation of lipid transport + + Any process involved in the carrying out of an immune response by a myeloid leukocyte. + myeloid leucocyte immune effector process + myeloid leucocyte mediated immunity + myeloid leukocyte immune effector process + biological_process + GO:0002444 + myeloid leukocyte mediated immunity + + + + Any process involved in the carrying out of an immune response by a myeloid leukocyte. + GOC:add + GO_REF:0000022 + ISBN:0781735149 + - + - + - + - - + + - - - - - - - - - - negative regulation of lipid transport + + Any process involved in the carrying out of an immune response by a lymphocyte. + cell-mediated immunity + cellular immune response + biological_process + GO:0002449 + lymphocyte mediated immunity + + + + Any process involved in the carrying out of an immune response by a lymphocyte. + GOC:add + GO_REF:0000022 + ISBN:0781735149 + - + - + - + - - + + - - - - - - - - - - positive regulation of lipid transport - - - - - - - - - - - - - - - - - - - - - actin filament bundle - - - - - - - - - multicellular organismal process + + + Any process involved in the carrying out of an immune response by a T cell. + cell-mediated immunity + cellular immune response + T lymphocyte mediated immunity + T-cell mediated immunity + T-lymphocyte mediated immunity + biological_process + GO:0002456 + T cell mediated immunity + + + + Any process involved in the carrying out of an immune response by a T cell. + GOC:add + GO_REF:0000022 + ISBN:0781735149 + - + - - - developmental process + + + An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains. Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies) produced by B cells. The first encounter with antigen elicits a primary immune response that is slow and not of great magnitude. T and B cells selected by antigen become activated and undergo clonal expansion. A fraction of antigen-reactive T and B cells become memory cells, whereas others differentiate into effector cells. The memory cells generated during the primary response enable a much faster and stronger secondary immune response upon subsequent exposures to the same antigen (immunological memory). An example of this is the adaptive immune response found in Mus musculus. + biological_process + GO:0002460 + adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains + + + + An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains. Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies) produced by B cells. The first encounter with antigen elicits a primary immune response that is slow and not of great magnitude. T and B cells selected by antigen become activated and undergo clonal expansion. A fraction of antigen-reactive T and B cells become memory cells, whereas others differentiate into effector cells. The memory cells generated during the primary response enable a much faster and stronger secondary immune response upon subsequent exposures to the same antigen (immunological memory). An example of this is the adaptive immune response found in Mus musculus. + GOC:add + GOC:mtg_sensu + ISBN:0781735149 + ISBN:1405196831 + - + - - - - multicellular organism reproduction + + + + + + + + + + + + + + The process in which germinal centers form. A germinal center is a specialized microenvironment formed when activated B cells enter lymphoid follicles. Germinal centers are the foci for B cell proliferation and somatic hypermutation. + biological_process + GO:0002467 + germinal center formation + + + + The process in which germinal centers form. A germinal center is a specialized microenvironment formed when activated B cells enter lymphoid follicles. Germinal centers are the foci for B cell proliferation and somatic hypermutation. + GOC:jal + GO_REF:0000022 + ISBN:081533642X + - + - - - monocarboxylic acid metabolic process + + + + + + + + + + + + + + + The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process. + biological_process + GO:0002520 + + immune system development + + + + The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process. + GOC:add + GOC:dph + - + - + - + - - + + - + - + - plasma membrane bounded cell projection cytoplasm + The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a leukocyte. A leukocyte is an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue. + immune cell differentiation + leucocyte differentiation + biological_process + GO:0002521 + leukocyte differentiation + + + + The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a leukocyte. A leukocyte is an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue. + CL:0000738 + GOC:add + PMID:16551264 + - + - + - + - + - - - - - - - - dendrite cytoplasm + + The movement of a leukocyte within or between different tissues and organs of the body as part of an immune response. + immune cell migration during immune response + immune cell trafficking during immune response + leucocyte migration during immune response + leucocyte trafficking during immune response + leukocyte trafficking during immune response + biological_process + GO:0002522 + leukocyte migration involved in immune response + + + + The movement of a leukocyte within or between different tissues and organs of the body as part of an immune response. + GOC:add + ISBN:0781735149 + PMID:14680625 + PMID:14708592 + PMID:7507411 + PMID:8600538 + - + - + - + - - + + - + The movement of a leukocyte within or between different tissues and organs of the body contributing to an inflammatory response. + biological_process + immune cell migration during inflammatory response + immune cell trafficking during inflammatory response + leucocyte migration during inflammatory response + leucocyte trafficking during inflammatory response + leukocyte migration during inflammatory response + leukocyte trafficking during inflammatory response + GO:0002523 + leukocyte migration involved in inflammatory response + + + + + The movement of a leukocyte within or between different tissues and organs of the body contributing to an inflammatory response. + GOC:add + ISBN:0781735149 + PMID:14680625 + PMID:14708592 + PMID:7507411 + PMID:8600538 + + + + + leukocyte migration during inflammatory response + GOC:dph + + + + + + + + - - + + - regulation of localization + The synthesis or release of any molecular mediator of the inflammatory response following an inflammatory stimulus, resulting in an increase in its intracellular or extracellular levels. + production of molecular mediator involved in acute inflammatory response + biological_process + production of cellular mediator of acute inflammation + GO:0002532 + production of molecular mediator involved in inflammatory response + + + + The synthesis or release of any molecular mediator of the inflammatory response following an inflammatory stimulus, resulting in an increase in its intracellular or extracellular levels. + GOC:add + GOC:dph + GOC:tb + ISBN:0781735149 + - + - + - + - - + + - + - - + + - regulation of protein localization + The regulated release of serotonin by a platelet or group of platelets. + biological_process + serotonin release by platelet + GO:0002554 + serotonin secretion by platelet + + + + The regulated release of serotonin by a platelet or group of platelets. + GOC:add + ISBN:0781735149 + + + + + serotonin release by platelet + GOC:tb + - + - + - + - - + + - - + - - + + - regulation of polysaccharide metabolic process + The regulated release of histamine by a platelet or group of platelets. + biological_process + GO:0002555 + histamine secretion by platelet + + + + The regulated release of histamine by a platelet or group of platelets. + GOC:add + PMID:9117517 + - + - + - + - - + + - - - - - - - - - - regulation of polysaccharide biosynthetic process + + + The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte lineage. + myeloid leucocyte differentiation + biological_process + GO:0002573 + myeloid leukocyte differentiation + + + + The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte lineage. + GOC:add + PMID:16551251 + - + - + - + - - + + - - - - - - - - regulation of microtubule-based process + + The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet. + platelet exocytosis + biological_process + GO:0002576 + platelet degranulation + + + + The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet. + GOC:add + - + - + - + - - + - regulation of organic acid transport + Any process that modulates the frequency, rate, or extent of germinal center formation. + biological_process + GO:0002634 + regulation of germinal center formation + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate, or extent of germinal center formation. + GOC:add + - + - + - + - - - - - - - - - negative regulation of organic acid transport + Any process that stops, prevents, or reduces the frequency, rate, or extent of germinal center formation. + down regulation of germinal center formation + down-regulation of germinal center formation + downregulation of germinal center formation + inhibition of germinal center formation + biological_process + GO:0002635 + negative regulation of germinal center formation + + + + Any process that stops, prevents, or reduces the frequency, rate, or extent of germinal center formation. + GOC:add + - + - + - + - - - - - - - - - positive regulation of organic acid transport - - - - - - - - - - secretion by cell - - - - - - - - - - secretion by tissue - - - - - - - - - mononuclear cell proliferation + Any process that activates or increases the frequency, rate, or extent of germinal center formation. + up regulation of germinal center formation + up-regulation of germinal center formation + upregulation of germinal center formation + activation of germinal center formation + stimulation of germinal center formation + biological_process + GO:0002636 + positive regulation of germinal center formation + + + + Any process that activates or increases the frequency, rate, or extent of germinal center formation. + GOC:add + - + - + - + - - - - - - - - regulation of mononuclear cell proliferation + + Any process that modulates the frequency, rate, or extent of immunoglobulin production. + GO:0002640 + GO:0051023 + regulation of antibody production + regulation of immunoglobulin biosynthetic process + regulation of immunoglobulin secretion + biological_process + GO:0002637 + regulation of immunoglobulin production + + + + Any process that modulates the frequency, rate, or extent of immunoglobulin production. + GOC:add + - + - + - + - - - - - - - - - negative regulation of mononuclear cell proliferation + + + Any process that stops, prevents, or reduces the frequency, rate, or extent of immunoglobulin production. + GO:0002641 + GO:0051025 + down regulation of immunoglobulin production + down-regulation of immunoglobulin production + downregulation of immunoglobulin production + inhibition of immunoglobulin production + negative regulation of immunoglobulin biosynthetic process + negative regulation of immunoglobulin secretion + biological_process + GO:0002638 + negative regulation of immunoglobulin production + + + + Any process that stops, prevents, or reduces the frequency, rate, or extent of immunoglobulin production. + GOC:add + - + - + - + - - - - - - - - - positive regulation of mononuclear cell proliferation - - - - - - - - - protein-containing complex - - - - - - - - - macromolecule localization + + Any process that activates or increases the frequency, rate, or extent of immunoglobulin production. + GO:0002642 + GO:0051024 + up regulation of immunoglobulin production + up-regulation of immunoglobulin production + upregulation of immunoglobulin production + activation of immunoglobulin production + positive regulation of immunoglobulin biosynthetic process + positive regulation of immunoglobulin secretion + stimulation of immunoglobulin production + biological_process + GO:0002639 + positive regulation of immunoglobulin production + + + + Any process that activates or increases the frequency, rate, or extent of immunoglobulin production. + GOC:add + - + - + - + - - - - - - - - regulation of organelle organization + + Any process that modulates the frequency, rate, or extent of an immune system process. + biological_process + GO:0002682 + regulation of immune system process + + + + Any process that modulates the frequency, rate, or extent of an immune system process. + GOC:add + - + - + - - + + - - - - - - - - - regulation of cellular amine metabolic process + + + Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process. + down regulation of immune system process + down-regulation of immune system process + downregulation of immune system process + inhibition of immune system process + biological_process + GO:0002683 + negative regulation of immune system process + + + + Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process. + GOC:add + - + - + - - + + - - - - - - - - - - negative regulation of cellular amine metabolic process + + + Any process that activates or increases the frequency, rate, or extent of an immune system process. + up regulation of immune system process + up-regulation of immune system process + upregulation of immune system process + activation of immune system process + stimulation of immune system process + biological_process + GO:0002684 + positive regulation of immune system process + + + + Any process that activates or increases the frequency, rate, or extent of an immune system process. + GOC:add + - + - + - - + + - - - - - - - - - - positive regulation of cellular amine metabolic process + Any process that modulates the frequency, rate, or extent of leukocyte migration. + regulation of immune cell migration + regulation of leucocyte migration + biological_process + GO:0002685 + regulation of leukocyte migration + + + + Any process that modulates the frequency, rate, or extent of leukocyte migration. + GOC:add + - + - + - + - - - - - - - - - - negative regulation of catecholamine secretion + Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte migration. + down regulation of leukocyte migration + down-regulation of leukocyte migration + downregulation of leukocyte migration + negative regulation of immune cell migration + negative regulation of leucocyte migration + inhibition of leukocyte migration + biological_process + GO:0002686 + negative regulation of leukocyte migration + + + + Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte migration. + GOC:add + - + - + - + - - - - - - - - - - positive regulation of catecholamine secretion + Any process that activates or increases the frequency, rate, or extent of leukocyte migration. + positive regulation of immune cell migration + positive regulation of leucocyte migration + up regulation of leukocyte migration + up-regulation of leukocyte migration + upregulation of leukocyte migration + activation of leukocyte migration + stimulation of leukocyte migration + biological_process + GO:0002687 + positive regulation of leukocyte migration + + + + Any process that activates or increases the frequency, rate, or extent of leukocyte migration. + GOC:add + - - - - - - - - cellular polysaccharide biosynthetic process - - - - - + - + - + - - - - - - - - - regulation of cellular amide metabolic process + + + Any process that modulates the frequency, rate, or extent of leukocyte activation. + regulation of immune cell activation + regulation of leucocyte activation + biological_process + GO:0002694 + regulation of leukocyte activation + + + + Any process that modulates the frequency, rate, or extent of leukocyte activation. + GOC:add + - + - + - + - - - - - - - - - - negative regulation of cellular amide metabolic process + + + + Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte activation. + down regulation of leukocyte activation + down-regulation of leukocyte activation + downregulation of leukocyte activation + negative regulation of immune cell activation + negative regulation of leucocyte activation + inhibition of leukocyte activation + biological_process + GO:0002695 + negative regulation of leukocyte activation + + + + Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte activation. + GOC:add + - + - + - + - - - - - - - - - - positive regulation of cellular amide metabolic process + + + + Any process that activates or increases the frequency, rate, or extent of leukocyte activation. + positive regulation of immune cell activation + positive regulation of leucocyte activation + up regulation of leukocyte activation + up-regulation of leukocyte activation + upregulation of leukocyte activation + activation of leukocyte activation + stimulation of leukocyte activation + biological_process + GO:0002696 + positive regulation of leukocyte activation + + + + Any process that activates or increases the frequency, rate, or extent of leukocyte activation. + GOC:add + - + - - - primary alcohol metabolic process + + + + + + + + + + + + + + Any process that modulates the frequency, rate, or extent of an immune effector process. + biological_process + GO:0002697 + regulation of immune effector process + + + + Any process that modulates the frequency, rate, or extent of an immune effector process. + GOC:add + - + - - - - primary alcohol biosynthetic process + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune effector process. + down regulation of immune effector process + down-regulation of immune effector process + downregulation of immune effector process + inhibition of immune effector process + biological_process + GO:0002698 + negative regulation of immune effector process + + + + Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune effector process. + GOC:add + - + - - - - - cellular carbohydrate biosynthetic process + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate, or extent of an immune effector process. + up regulation of immune effector process + up-regulation of immune effector process + upregulation of immune effector process + activation of immune effector process + stimulation of immune effector process + biological_process + GO:0002699 + positive regulation of immune effector process + + + + Any process that activates or increases the frequency, rate, or extent of an immune effector process. + GOC:add + - + - - - - cellular nitrogen compound metabolic process + + + + + + + + + + + + + + Any process that modulates the frequency, rate, or extent of the production of molecular mediator of immune response. + biological_process + GO:0002700 + regulation of production of molecular mediator of immune response + + + + Any process that modulates the frequency, rate, or extent of the production of molecular mediator of immune response. + GOC:add + - + - - - - - cellular macromolecule biosynthetic process + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate, or extent of the production of molecular mediator of immune response. + down regulation of production of molecular mediator of immune response + down-regulation of production of molecular mediator of immune response + downregulation of production of molecular mediator of immune response + inhibition of production of molecular mediator of immune response + biological_process + GO:0002701 + negative regulation of production of molecular mediator of immune response + + + + Any process that stops, prevents, or reduces the frequency, rate, or extent of the production of molecular mediator of immune response. + GOC:add + - + - - - - cellular hormone metabolic process + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate, or extent of the production of molecular mediator of immune response. + up regulation of production of molecular mediator of immune response + up-regulation of production of molecular mediator of immune response + upregulation of production of molecular mediator of immune response + activation of production of molecular mediator of immune response + stimulation of production of molecular mediator of immune response + biological_process + GO:0002702 + positive regulation of production of molecular mediator of immune response + + + + Any process that activates or increases the frequency, rate, or extent of the production of molecular mediator of immune response. + GOC:add + - + - - - - - - - - - tube formation + + + + + + + + + + + + + Any process that modulates the frequency, rate, or extent of leukocyte mediated immunity. + regulation of immune cell mediated immunity + regulation of leucocyte mediated immunity + biological_process + GO:0002703 + regulation of leukocyte mediated immunity + + + + Any process that modulates the frequency, rate, or extent of leukocyte mediated immunity. + GOC:add + - + - - - - - - - - - hatching + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte mediated immunity. + down regulation of leukocyte mediated immunity + down-regulation of leukocyte mediated immunity + downregulation of leukocyte mediated immunity + negative regulation of immune cell mediated immunity + negative regulation of leucocyte mediated immunity + inhibition of leukocyte mediated immunity + biological_process + GO:0002704 + negative regulation of leukocyte mediated immunity + + + + Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte mediated immunity. + GOC:add + - + - - - pupal development + + + + + + + + + + + + + Any process that activates or increases the frequency, rate, or extent of leukocyte mediated immunity. + positive regulation of immune cell mediated immunity + positive regulation of leucocyte mediated immunity + up regulation of leukocyte mediated immunity + up-regulation of leukocyte mediated immunity + upregulation of leukocyte mediated immunity + activation of leukocyte mediated immunity + stimulation of leukocyte mediated immunity + biological_process + GO:0002705 + positive regulation of leukocyte mediated immunity + + + + Any process that activates or increases the frequency, rate, or extent of leukocyte mediated immunity. + GOC:add + - + - - - - - - - - - tube morphogenesis + + + + + + + + + + + + + Any process that modulates the frequency, rate, or extent of lymphocyte mediated immunity. + biological_process + GO:0002706 + regulation of lymphocyte mediated immunity + + + + Any process that modulates the frequency, rate, or extent of lymphocyte mediated immunity. + GOC:add + - + - - - - - - - - - tube development + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte mediated immunity. + down regulation of lymphocyte mediated immunity + down-regulation of lymphocyte mediated immunity + downregulation of lymphocyte mediated immunity + inhibition of lymphocyte mediated immunity + biological_process + GO:0002707 + negative regulation of lymphocyte mediated immunity + + + + Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte mediated immunity. + GOC:add + - + - - - - establishment of protein localization to extracellular region + + + + + + + + + + + + + Any process that activates or increases the frequency, rate, or extent of lymphocyte mediated immunity. + up regulation of lymphocyte mediated immunity + up-regulation of lymphocyte mediated immunity + upregulation of lymphocyte mediated immunity + activation of lymphocyte mediated immunity + stimulation of lymphocyte mediated immunity + biological_process + GO:0002708 + positive regulation of lymphocyte mediated immunity + + + + Any process that activates or increases the frequency, rate, or extent of lymphocyte mediated immunity. + GOC:add + - + - - - - regulation of urine volume + + + + + + + + + + + + + Any process that modulates the frequency, rate, or extent of T cell mediated immunity. + regulation of T lymphocyte mediated immunity + regulation of T-cell mediated immunity + regulation of T-lymphocyte mediated immunity + biological_process + GO:0002709 + regulation of T cell mediated immunity + + + + Any process that modulates the frequency, rate, or extent of T cell mediated immunity. + GOC:add + - + - - - parathyroid hormone secretion + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell mediated immunity. + down regulation of T cell mediated immunity + down-regulation of T cell mediated immunity + downregulation of T cell mediated immunity + negative regulation of T lymphocyte mediated immunity + negative regulation of T-cell mediated immunity + negative regulation of T-lymphocyte mediated immunity + inhibition of T cell mediated immunity + biological_process + GO:0002710 + negative regulation of T cell mediated immunity + + + + Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell mediated immunity. + GOC:add + - + - - - - steroid hormone secretion + + + + + + + + + + + + + Any process that activates or increases the frequency, rate, or extent of T cell mediated immunity. + positive regulation of T lymphocyte mediated immunity + positive regulation of T-cell mediated immunity + positive regulation of T-lymphocyte mediated immunity + up regulation of T cell mediated immunity + up-regulation of T cell mediated immunity + upregulation of T cell mediated immunity + activation of T cell mediated immunity + stimulation of T cell mediated immunity + biological_process + GO:0002711 + positive regulation of T cell mediated immunity + + + + Any process that activates or increases the frequency, rate, or extent of T cell mediated immunity. + GOC:add + - + - - - corticosteroid hormone secretion + + + + + + + + + + + + + Any process that modulates the frequency, rate, or extent of B cell mediated immunity. + regulation of B lymphocyte mediated immunity + regulation of B-cell mediated immunity + regulation of B-lymphocyte mediated immunity + biological_process + GO:0002712 + regulation of B cell mediated immunity + + + + Any process that modulates the frequency, rate, or extent of B cell mediated immunity. + GOC:add + - + - - - mineralocorticoid secretion + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell mediated immunity. + down regulation of B cell mediated immunity + down-regulation of B cell mediated immunity + downregulation of B cell mediated immunity + negative regulation of B lymphocyte mediated immunity + negative regulation of B-cell mediated immunity + negative regulation of B-lymphocyte mediated immunity + inhibition of B cell mediated immunity + biological_process + GO:0002713 + negative regulation of B cell mediated immunity + + + + Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell mediated immunity. + GOC:add + - + - - - - aldosterone secretion + + + + + + + + + + + + + Any process that activates or increases the frequency, rate, or extent of B cell mediated immunity. + positive regulation of B lymphocyte mediated immunity + positive regulation of B-cell mediated immunity + positive regulation of B-lymphocyte mediated immunity + up regulation of B cell mediated immunity + up-regulation of B cell mediated immunity + upregulation of B cell mediated immunity + activation of B cell mediated immunity + stimulation of B cell mediated immunity + biological_process + GO:0002714 + positive regulation of B cell mediated immunity + + + + Any process that activates or increases the frequency, rate, or extent of B cell mediated immunity. + GOC:add + - + - - - direct ossification + + + + + + + + + + + + + Any process that modulates the frequency, rate, or extent of myeloid leukocyte differentiation. + biological_process + GO:0002761 + regulation of myeloid leukocyte differentiation + + + + Any process that modulates the frequency, rate, or extent of myeloid leukocyte differentiation. + GOC:add + - + - - - perichondral ossification + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte differentiation. + down regulation of myeloid leukocyte differentiation + down-regulation of myeloid leukocyte differentiation + downregulation of myeloid leukocyte differentiation + inhibition of myeloid leukocyte differentiation + biological_process + GO:0002762 + negative regulation of myeloid leukocyte differentiation + + + + Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte differentiation. + GOC:add + - + - - - replacement ossification + + + + + + + + + + + + + Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte differentiation. + up regulation of myeloid leukocyte differentiation + up-regulation of myeloid leukocyte differentiation + upregulation of myeloid leukocyte differentiation + activation of myeloid leukocyte differentiation + stimulation of myeloid leukocyte differentiation + biological_process + GO:0002763 + positive regulation of myeloid leukocyte differentiation + + + + Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte differentiation. + GOC:add + - + - - - rumination + + + + + + + + + + + + + + + The controlled release of a peptide from a cell or a tissue. + biological_process + GO:0002790 + peptide secretion + + + + The controlled release of a peptide from a cell or a tissue. + GOC:add + - + - - - calcitonin secretion + + + + + + + + + + + + + + + Any process that modulates the frequency, rate, or extent of peptide secretion. + biological_process + GO:0002791 + regulation of peptide secretion + + + + Any process that modulates the frequency, rate, or extent of peptide secretion. + GOC:add + - - - - - muscle cell projection - - + - - - - - - response to decreased oxygen levels - - - - - - - - - - - - - - - myofilament - - - - - - - - - somatodendritic compartment + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate, or extent of peptide secretion. + down regulation of peptide secretion + down-regulation of peptide secretion + downregulation of peptide secretion + inhibition of peptide secretion + biological_process + GO:0002792 + negative regulation of peptide secretion + + + + Any process that stops, prevents, or reduces the frequency, rate, or extent of peptide secretion. + GOC:add + - + - - - signaling receptor activity + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate, or extent of peptide secretion. + up regulation of peptide secretion + up-regulation of peptide secretion + upregulation of peptide secretion + activation of peptide secretion + stimulation of peptide secretion + biological_process + GO:0002793 + positive regulation of peptide secretion + + + + Any process that activates or increases the frequency, rate, or extent of peptide secretion. + GOC:add + - + - - - growth + + + + + + + + + + + + + Any process that modulates the frequency, rate, or extent of an adaptive immune response. + biological_process + GO:0002819 + regulation of adaptive immune response + + + + Any process that modulates the frequency, rate, or extent of an adaptive immune response. + GOC:add + - + - + - - + + - - - - - - - - regulation of growth + Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response. + down regulation of adaptive immune response + down-regulation of adaptive immune response + downregulation of adaptive immune response + inhibition of adaptive immune response + biological_process + GO:0002820 + negative regulation of adaptive immune response + + + + Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response. + GOC:add + - + - - - locomotion + + + + + + + + + + + + + Any process that activates or increases the frequency, rate, or extent of an adaptive immune response. + up regulation of adaptive immune response + up-regulation of adaptive immune response + upregulation of adaptive immune response + activation of adaptive immune response + stimulation of adaptive immune response + biological_process + GO:0002821 + positive regulation of adaptive immune response + + + + Any process that activates or increases the frequency, rate, or extent of an adaptive immune response. + GOC:add + - + - + - + - + + + + + + - + - regulation of locomotion + + + + + + + Any process that modulates the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata. + biological_process + GO:0002822 + regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains + + + + Any process that modulates the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata. + GOC:add + GOC:mtg_sensu + - + - + - + - - - - - - - - - negative regulation of locomotion - - - - - - - - - - - - - - - embryonic cleavage + Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata. + biological_process + GO:0002823 + negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains + + + + Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata. + GOC:add + GOC:mtg_sensu + - + - + - + - - - - - - - - - positive regulation of locomotion + Any process that activates or increases the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata. + biological_process + GO:0002824 + positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains + + + + Any process that activates or increases the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata. + GOC:add + GOC:mtg_sensu + - + - + - - + + - - - - - - - - - - positive regulation of embryonic development + Any process that modulates the frequency, rate, or extent of a response to biotic stimulus. + biological_process + GO:0002831 + + Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. + regulation of response to biotic stimulus + + + + Any process that modulates the frequency, rate, or extent of a response to biotic stimulus. + GOC:add + - + - + - - + + - - - - - - - - - - regulation of meiotic nuclear division + Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to biotic stimulus. + down regulation of response to biotic stimulus + down-regulation of response to biotic stimulus + downregulation of response to biotic stimulus + inhibition of response to biotic stimulus + biological_process + GO:0002832 + + Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. + negative regulation of response to biotic stimulus + + + + Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to biotic stimulus. + GOC:add + - + - - - fluid transport + + + + + + + + + + + + + Any process that activates or increases the frequency, rate, or extent of a response to biotic stimulus. + up regulation of response to biotic stimulus + up-regulation of response to biotic stimulus + upregulation of response to biotic stimulus + activation of response to biotic stimulus + stimulation of response to biotic stimulus + biological_process + GO:0002833 + + Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. + positive regulation of response to biotic stimulus + + + + Any process that activates or increases the frequency, rate, or extent of a response to biotic stimulus. + GOC:add + - + - - - olfactory behavior + + + + + + + + + + + + + Any process that modulates the frequency, rate, or extent of myeloid leukocyte mediated immunity. + biological_process + GO:0002886 + regulation of myeloid leukocyte mediated immunity + + + + Any process that modulates the frequency, rate, or extent of myeloid leukocyte mediated immunity. + GOC:add + - + - - - - - - - - - wound healing + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte mediated immunity. + down regulation of myeloid leukocyte mediated immunity + down-regulation of myeloid leukocyte mediated immunity + downregulation of myeloid leukocyte mediated immunity + inhibition of myeloid leukocyte mediated immunity + biological_process + GO:0002887 + negative regulation of myeloid leukocyte mediated immunity + + + + Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte mediated immunity. + GOC:add + - + - + - - + + - - - - - - - - - regulation of catecholamine metabolic process + Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte mediated immunity. + up regulation of myeloid leukocyte mediated immunity + up-regulation of myeloid leukocyte mediated immunity + upregulation of myeloid leukocyte mediated immunity + activation of myeloid leukocyte mediated immunity + stimulation of myeloid leukocyte mediated immunity + biological_process + GO:0002888 + positive regulation of myeloid leukocyte mediated immunity + + + + Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte mediated immunity. + GOC:add + - + - + - + - - + + - + - + - cell migration involved in gastrulation - - - - - - - - - - B cell proliferation - - - - - - - - - T cell activation + The progression of the trabecular meshwork over time, from its formation to the mature structure. The trabecular meshwork is a fenestrated endothelial-like tissue situated at the intersection of the cornea and the iris. The trabecular meshwork provides drainage for the aqueous humor. + hjd + 2012-04-19T04:50:06Z + biological_process + GO:0002930 + trabecular meshwork development + + + + The progression of the trabecular meshwork over time, from its formation to the mature structure. The trabecular meshwork is a fenestrated endothelial-like tissue situated at the intersection of the cornea and the iris. The trabecular meshwork provides drainage for the aqueous humor. + PMID:20568247 + - - - - - B cell activation - - - + - - - + - + - - + + - + - - + + - regulation of cell population proliferation - - - - - - - - - - - cellular ketone metabolic process - - - - - - - - - - - - ketone biosynthetic process - - - - - - - - - response to chemical + The process whose specific outcome is the progression of a tendon sheath over time, from its formation to the mature structure. A tendon sheath is a layer of membrane around a tendon. It permits the tendon to move. + hjd + 2012-04-23T02:11:22Z + biological_process + GO:0002932 + tendon sheath development + + + + The process whose specific outcome is the progression of a tendon sheath over time, from its formation to the mature structure. A tendon sheath is a layer of membrane around a tendon. It permits the tendon to move. + PMID:20696843 + - + - - - - tissue regeneration + + + The pattern specification process that results in the subdivision of an axis or axes in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment. + biological_process + pattern formation + GO:0003002 + regionalization + + + + The pattern specification process that results in the subdivision of an axis or axes in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment. + GOC:dph + GOC:isa_complete + + + + + pattern formation + GOC:dph + - + - + - + - - + + - - - - - - - - - - - negative regulation of circadian sleep/wake cycle, sleep + + + A developmental process in which a progressive change in the state of some part of an organism, germline or somatic, specifically contributes to its ability to form offspring. + puberty + biological_process + reproductive developmental process + GO:0003006 + developmental process involved in reproduction + + + + A developmental process in which a progressive change in the state of some part of an organism, germline or somatic, specifically contributes to its ability to form offspring. + GOC:dph + GOC:isa_complete + + + + + puberty + GOC:dph + + + + + reproductive developmental process + GOC:dph + GOC:tb + - + - + - + - - + + - - + - - + + - negative regulation of circadian sleep/wake cycle, non-REM sleep + The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. + biological_process + cardiac morphogenesis + GO:0003007 + heart morphogenesis + + + + The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. + GOC:dph + GOC:isa_complete + - + - - - - - thyroid hormone metabolic process + + + A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective. + organ system process + biological_process + GO:0003008 + system process + + + + A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective. + GOC:mtg_cardio + - + - - - - - - serotonin metabolic process + + + + + + + + + + + + + + + + + + + + A process in which force is generated within skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and in most cases it is under voluntary control. + biological_process + GO:0003009 + skeletal muscle contraction + + + + A process in which force is generated within skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and in most cases it is under voluntary control. + GOC:mtg_cardio + GOC:mtg_muscle + - + - - - - - - - indole-containing compound metabolic process + + + A organ system process carried out at the level of a muscle. Muscle tissue is composed of contractile cells or fibers. + biological_process + muscle physiological process + GO:0003012 + + + muscle system process + + + + A organ system process carried out at the level of a muscle. Muscle tissue is composed of contractile cells or fibers. + GOC:mtg_cardio + - + - - - - - - - - indole-containing compound biosynthetic process + + + A organ system process carried out by any of the organs or tissues of the circulatory system. The circulatory system is an organ system that moves extracellular fluids to and from tissue within a multicellular organism. + Wikipedia:Circulatory_system + biological_process + GO:0003013 + + + circulatory system process + + + + A organ system process carried out by any of the organs or tissues of the circulatory system. The circulatory system is an organ system that moves extracellular fluids to and from tissue within a multicellular organism. + GOC:mtg_cardio + - + - - - - hormone metabolic process + + + A organ system process carried out by any of the organs or tissues of the renal system. The renal system maintains fluid balance, and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels; in other species, the renal system may comprise related structures (e.g., nephrocytes and malpighian tubules in Drosophila). + excretory system process + biological_process + kidney system process + GO:0003014 + + renal system process + + + + A organ system process carried out by any of the organs or tissues of the renal system. The renal system maintains fluid balance, and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels; in other species, the renal system may comprise related structures (e.g., nephrocytes and malpighian tubules in Drosophila). + GOC:cjm + GOC:mtg_cardio + GOC:mtg_kidney_jan10 + - + - - - - hormone biosynthetic process + + + A circulatory system process carried out by the heart. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. + biological_process + cardiac process + GO:0003015 + heart process + + + + A circulatory system process carried out by the heart. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. + GOC:mtg_cardio + - + - - - homeostatic process + + + + + + + + + A process carried out by the organs or tissues of the respiratory system. The respiratory system is an organ system responsible for respiratory gaseous exchange. + GO:0010802 + respiratory gaseous exchange + biological_process + GO:0003016 + + respiratory system process + + + + A process carried out by the organs or tissues of the respiratory system. The respiratory system is an organ system responsible for respiratory gaseous exchange. + GOC:dph + GOC:mtg_cardio + GOC:tb + - + - - - - ovulation cycle + + + The flow of lymph through the body of an animal. + biological_process + GO:0003017 + lymph circulation + + + + The flow of lymph through the body of an animal. + GOC:mtg_cardio + - + - - - - + + - + - progesterone secretion + The neurological process in which nerve impulses arising in the aorta or the carotid sinuses travel to the medulla and reach the nucleus of tractus solaris. + biological_process + GO:0003019 + central nervous system control of baroreceptor feedback + + + + The neurological process in which nerve impulses arising in the aorta or the carotid sinuses travel to the medulla and reach the nucleus of tractus solaris. + GOC:mtg_cardio + ISBN:0323031951 + - + - - + + - + - sperm ejaculation + The process in which information about the levels of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies. + detection of reduced oxygen by chemoreceptor signalling + biological_process + GO:0003020 + detection of reduced oxygen by chemoreceptor signaling + + + + The process in which information about the levels of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies. + GOC:mtg_cardio + ISBN:0323031951 + + + + + detection of reduced oxygen by chemoreceptor signalling + GOC:mah + - + - - - circadian sleep/wake cycle + + + The process in which information about the levels of hydrogen ions are received and are converted to a molecular signal by chemoreceptors. + detection of pH by chemoreceptor signalling + biological_process + GO:0003022 + detection of pH by chemoreceptor signaling + + + + The process in which information about the levels of hydrogen ions are received and are converted to a molecular signal by chemoreceptors. + GOC:mtg_cardio + ISBN:0323031951 + + + + + detection of pH by chemoreceptor signalling + GOC:mah + - + - - - - - - - - - circadian sleep/wake cycle, non-REM sleep + + + The neural regulation of blood pressure in which baroreceptors sense the amount of stretch occurring in vessels and respond to the input via central nervous system control. + baroreceptor regulation of systemic arterial blood pressure + biological_process + GO:0003025 + regulation of systemic arterial blood pressure by baroreceptor feedback + + + + The neural regulation of blood pressure in which baroreceptors sense the amount of stretch occurring in vessels and respond to the input via central nervous system control. + GOC:dph + GOC:mtg_cardio + GOC:tb + + + + + baroreceptor regulation of systemic arterial blood pressure + GOC:dph + GOC:tb + - + - - - - - - - - - - - - - - - + + + The process that modulates blood pressure by the action of chemoreceptors found in the carotid bodies and their resultant modulation of the vasomotor center. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions. + vagal reflex + carotid body chemoreceptor regulation of systemic arterial blood pressure + carotid body chemoreceptor response to lowering of systemic arterial blood pressure + regulation of systemic arterial blood pressure by carotid body chemoreceptor signalling + biological_process + GO:0003027 + regulation of systemic arterial blood pressure by carotid body chemoreceptor signaling + + + + + The process that modulates blood pressure by the action of chemoreceptors found in the carotid bodies and their resultant modulation of the vasomotor center. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions. + GOC:dph + GOC:mtg_cardio + GOC:tb + + + + + carotid body chemoreceptor regulation of systemic arterial blood pressure + GOC:dph + GOC:tb + + + + + carotid body chemoreceptor response to lowering of systemic arterial blood pressure + GOC:dph + + + + + regulation of systemic arterial blood pressure by carotid body chemoreceptor signalling + GOC:mah + + + + + + + + - - + + - regulation of circadian sleep/wake cycle + The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies. + detection of hypoxic conditions in blood by carotid body chemoreceptor signalling + biological_process + GO:0003029 + detection of hypoxic conditions in blood by carotid body chemoreceptor signaling + + + + The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies. + GOC:mtg_cardio + + + + + detection of hypoxic conditions in blood by carotid body chemoreceptor signalling + GOC:mah + - + - - - - - - - - - - - - - + + + The series of events in which a hydrogen ion stimulus is received by a cell and converted into a molecular signal. + biological_process + GO:0003030 + detection of hydrogen ion + + + + + The series of events in which a hydrogen ion stimulus is received by a cell and converted into a molecular signal. + GOC:mtg_cardio + + + + + + + + + + The series of events in which an oxygen stimulus is received by a cell and converted into a molecular signal. + biological_process + GO:0003032 + detection of oxygen + + + + + The series of events in which an oxygen stimulus is received by a cell and converted into a molecular signal. + GOC:mtg_cardio + + + + + + + + - - + + - regulation of circadian rhythm + The process in which information about the levels of oxygen are received and are converted to a molecular signal by chemoreceptors in a carotid body. + detection of reduced oxygen by carotid body chemoreceptor signalling + biological_process + GO:0003039 + detection of reduced oxygen by carotid body chemoreceptor signaling + + + + The process in which information about the levels of oxygen are received and are converted to a molecular signal by chemoreceptors in a carotid body. + GOC:mtg_cardio + + + + + detection of reduced oxygen by carotid body chemoreceptor signalling + GOC:mah + - + - + + + The regulation of blood pressure mediated by biochemical signaling: hormonal, autocrine or paracrine. + blood pressure regulation mediated by a chemical signal + biological_process + GO:0003044 + regulation of systemic arterial blood pressure mediated by a chemical signal + + + + + The regulation of blood pressure mediated by biochemical signaling: hormonal, autocrine or paracrine. + GOC:mtg_cardio + + + + + + + - + - - + + - - - - - - - - - positive regulation of circadian rhythm + + Renal process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure. + renal control of blood pressure + renal regulation of systemic arterial blood pressure + biological_process + GO:0003071 + renal system process involved in regulation of systemic arterial blood pressure + + + + Renal process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure. + GOC:dph + GOC:mtg_cardio + GOC:tb + + + + + renal regulation of systemic arterial blood pressure + GOC:dph + GOC:tb + - + - + - - + + - - - - - - - - - negative regulation of circadian rhythm + + The process that modulates the force with which blood travels through the systemic arterial circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure. + biological_process + GO:0003073 + regulation of systemic arterial blood pressure + + + + The process that modulates the force with which blood travels through the systemic arterial circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure. + GOC:mtg_cardio + - + - - - amide transport + + + The process in which renin-angiotensin modulates the force with which blood passes through the circulatory system. + blood pressure regulation by renin-angiotensin + biological_process + GO:0003081 + regulation of systemic arterial blood pressure by renin-angiotensin + + + + The process in which renin-angiotensin modulates the force with which blood passes through the circulatory system. + GOC:mtg_cardio + - + - - - cell projection + + + + + + + + + + + + + + + Renal process involved in the maintenance of an internal steady state of water in the body. + water homeostasis by the renal system + biological_process + GO:0003091 + renal water homeostasis + + + + Renal process involved in the maintenance of an internal steady state of water in the body. + GOC:mtg_cardio + - + - - - neuron projection + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of glomerular filtration. Glomerular filtration is the process in which blood is filtered by the glomerulus into the renal tubule. + biological_process + GO:0003093 + regulation of glomerular filtration + + + + Any process that modulates the frequency, rate or extent of glomerular filtration. Glomerular filtration is the process in which blood is filtered by the glomerulus into the renal tubule. + GOC:mtg_cardio + - + - - - chordate embryonic development + + + + + + + + + + + + + + The process in which plasma is filtered through the glomerular membrane which consists of capillary endothelial cells, the basement membrane, and epithelial cells. The glomerular filtrate is the same as plasma except it has no significant amount of protein. + biological_process + GO:0003094 + glomerular filtration + + + + The process in which plasma is filtered through the glomerular membrane which consists of capillary endothelial cells, the basement membrane, and epithelial cells. The glomerular filtrate is the same as plasma except it has no significant amount of protein. + GOC:mtg_cardio + GOC:sart + ISBN:0721643949 + - + - - + + + + + + + + + + + + + + + The directed movement of sodium ions (Na+) by the renal system. + biological_process + GO:0003096 + renal sodium ion transport + + + + + The directed movement of sodium ions (Na+) by the renal system. + GOC:mtg_cardio + + + + + + + + + + + + + + + + + + + + + - + - neuronal cell body + The directed movement of water (H2O) by the renal system. + biological_process + GO:0003097 + renal water transport + + + + The directed movement of water (H2O) by the renal system. + GOC:mtg_cardio + - + - - - extracellular structure organization + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of glomerular filtration. Glomerular filtration is the processs whereby blood is filtered by the glomerulus into the renal tubule. + biological_process + GO:0003104 + positive regulation of glomerular filtration + + + + Any process that activates or increases the frequency, rate or extent of glomerular filtration. Glomerular filtration is the processs whereby blood is filtered by the glomerulus into the renal tubule. + GOC:mtg_cardio + - + - - - germ cell nucleus + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of glomerular filtration. Glomerular filtration is the processs whereby blood is filtered by the glomerulus into the renal tubule. + biological_process + GO:0003105 + negative regulation of glomerular filtration + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of glomerular filtration. Glomerular filtration is the processs whereby blood is filtered by the glomerulus into the renal tubule. + GOC:mtg_cardio + - + - - + + + + + + + + + + + + + + - + - penile erection - - - - - - - - - macromolecule metabolic process - - - - - - - - - myelin sheath + The process in which the anatomical structures of the cardiogenic plate are generated and organized. The cardiogenic plate is the first recognizable structure derived from the heart field. + tb + 2009-09-22T04:12:18Z + cardiac crescent morphogenesis + biological_process + GO:0003142 + cardiogenic plate morphogenesis + + + + The process in which the anatomical structures of the cardiogenic plate are generated and organized. The cardiogenic plate is the first recognizable structure derived from the heart field. + GOC:mtg_heart + + + + + cardiac crescent morphogenesis + GOC:mtg_heart + - + - - - organelle + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the embryonic heart tube are generated and organized. The embryonic heart tube is an epithelial tube that will give rise to the mature heart. + tb + 2009-09-22T04:21:17Z + biological_process + GO:0003143 + embryonic heart tube morphogenesis + + + + The process in which the anatomical structures of the embryonic heart tube are generated and organized. The embryonic heart tube is an epithelial tube that will give rise to the mature heart. + GOC:mtg_heart + - + - + - + - - + + - + - - + + - membrane-bounded organelle + The process that gives rise to the embryonic heart tube. This process pertains to the initial formation of a structure from unspecified parts. The embryonic heart tube is an epithelial tube that will give rise to the mature heart. + tb + 2009-09-22T04:22:34Z + biological_process + GO:0003144 + embryonic heart tube formation + + + + The process that gives rise to the embryonic heart tube. This process pertains to the initial formation of a structure from unspecified parts. The embryonic heart tube is an epithelial tube that will give rise to the mature heart. + GOC:mtg_heart + - + - - - non-membrane-bounded organelle + + + The process that gives rise to the embryonic heart tube by the cells of the heart field along a linear axis. + tb + 2009-09-22T04:26:03Z + biological_process + GO:0003145 + embryonic heart tube formation via epithelial folding + + + + The process that gives rise to the embryonic heart tube by the cells of the heart field along a linear axis. + GOC:mtg_heart + - + - + - + - + - - + - intracellular organelle + The characteristic movement of a cell from the dorsal ridge of the neural tube towards the heart and that contributes to heart formation. + tb + 2009-09-22T04:29:55Z + biological_process + GO:0003147 + neural crest cell migration involved in heart formation + + + + The characteristic movement of a cell from the dorsal ridge of the neural tube towards the heart and that contributes to heart formation. + GOC:mtg_heart + - + - + - + - - + + - + - + - extracellular organelle + The process in which the anatomical structures of the outflow tract septum are generated and organized. The outflow tract septum is a partition in the outflow tract. + tb + 2009-09-22T07:51:01Z + biological_process + GO:0003148 + outflow tract septum morphogenesis + + + + The process in which the anatomical structures of the outflow tract septum are generated and organized. The outflow tract septum is a partition in the outflow tract. + GOC:mtg_heart + - + - + - + - - + + - - - intracellular membrane-bounded organelle + + + + + + + + + The process in which the membranous septum is generated and organized. The membranous septum is the upper part of ventricular septum. + tb + 2009-09-22T07:51:41Z + biological_process + GO:0003149 + membranous septum morphogenesis + + + + The process in which the membranous septum is generated and organized. The membranous septum is the upper part of ventricular septum. + GOC:mtg_heart + - + - + - + - - + + - - - intracellular non-membrane-bounded organelle + + + + + + + + + The process in which the muscular septum is generated and organized. The muscular septum is the lower part of the ventricular septum. + tb + 2009-09-22T07:53:28Z + biological_process + GO:0003150 + muscular septum morphogenesis + + + + The process in which the muscular septum is generated and organized. The muscular septum is the lower part of the ventricular septum. + GOC:mtg_heart + - + - + - + - - + + - - + + - - + + - regulation of carbohydrate biosynthetic process + The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries. + tb + 2009-09-22T07:59:24Z + biological_process + GO:0003151 + outflow tract morphogenesis + + + + The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries. + GOC:mtg_heart + UBERON:0004145 + - + - + - + - + - - - extracellular non-membrane-bounded organelle + + + + + + + + The morphogenetic process in which an epithelial sheet bends along a linear axis, contributing to embryonic heart tube formation. + tb + 2009-09-23T10:10:24Z + biological_process + GO:0003152 + morphogenesis of an epithelial fold involved in embryonic heart tube formation + + + + The morphogenetic process in which an epithelial sheet bends along a linear axis, contributing to embryonic heart tube formation. + GOC:mtg_heart + - + - + - + - - + - regulation of ion transport + Any process that modulates the rate, frequency or extent of animal organ formation. Organ formation is the process pertaining to the initial formation of an organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment. + tb + 2009-09-30T11:21:09Z + biological_process + GO:0003156 + regulation of animal organ formation + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the rate, frequency or extent of animal organ formation. Organ formation is the process pertaining to the initial formation of an organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment. + GOC:dph + GOC:mtg_heart + GOC:tb + - + - + - + - - + + - - + + - - + + - positive regulation of ion transport + The process whose specific outcome is the progression of the endocardium over time, from its formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. + dph + 2009-10-01T12:42:27Z + biological_process + GO:0003157 + endocardium development + + + + The process whose specific outcome is the progression of the endocardium over time, from its formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. + GOC:mtg_heart + - + - + - + - - + + - - - - - - - - - negative regulation of ion transport + + The process whose specific outcome is the progression of an endothelium over time, from its formation to the mature structure. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells. + dph + 2009-10-01T12:50:57Z + biological_process + GO:0003158 + endothelium development + + + + The process whose specific outcome is the progression of an endothelium over time, from its formation to the mature structure. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells. + GOC:mtg_heart + - + - - - + + + + + + + + + + + + + - + - contractile fiber - - - - - - - - - apical junction complex + The process in which the anatomical structure of an endothelium is generated and organized. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells. + dph + 2009-10-01T01:34:06Z + biological_process + GO:0003159 + morphogenesis of an endothelium + + + + The process in which the anatomical structure of an endothelium is generated and organized. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells. + GOC:mtg_heart + - + - - - oxoacid metabolic process + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of the endocardium is generated and organized. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. + dph + 2009-10-01T01:37:26Z + biological_process + GO:0003160 + endocardium morphogenesis + + + + The process in which the anatomical structure of the endocardium is generated and organized. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. + GOC:mtg_heart + - + - + - + - - + + - - - + + - regulation of generation of precursor metabolites and energy + The process whose specific outcome is the progression of the cardiac conduction system over time, from its formation to the mature structure. The cardiac conduction system consists of specialized cardiomyocytes that regulate the frequency of heart beat. + dph + 2009-10-01T01:57:16Z + cardiac impulse conducting system development + heart conduction system development + biological_process + GO:0003161 + cardiac conduction system development + + + + The process whose specific outcome is the progression of the cardiac conduction system over time, from its formation to the mature structure. The cardiac conduction system consists of specialized cardiomyocytes that regulate the frequency of heart beat. + GOC:mtg_heart + + + + + cardiac impulse conducting system development + GOC:mtg_heart + + + + + heart conduction system development + GOC:mtg_heart + - + - + - + - - + + - - - - + + - regulation of carbohydrate catabolic process + The process whose specific outcome is the progression of the atrioventricular (AV) node over time, from its formation to the mature structure. The AV node is part of the cardiac conduction system that controls the timing of ventricle contraction by receiving electrical signals from the sinoatrial (SA) node and relaying them to the His-Purkinje system. + dph + 2009-10-01T02:05:13Z + AV node development + biological_process + GO:0003162 + atrioventricular node development + + + + The process whose specific outcome is the progression of the atrioventricular (AV) node over time, from its formation to the mature structure. The AV node is part of the cardiac conduction system that controls the timing of ventricle contraction by receiving electrical signals from the sinoatrial (SA) node and relaying them to the His-Purkinje system. + GOC:mtg_heart + + + + + AV node development + GOC:mtg_heart + - + - + - + - - + + - - - - - - + + - regulation of cellular carbohydrate catabolic process + The process whose specific outcome is the progression of the sinoatrial (SA) node over time, from its formation to the mature structure. The SA node is part of the cardiac conduction system that controls the timing of heart muscle contraction. It relays electrical signals to the AV node. + dph + 2009-10-01T02:06:09Z + SA node development + SAN development + sinus node development + biological_process + GO:0003163 + sinoatrial node development + + + + The process whose specific outcome is the progression of the sinoatrial (SA) node over time, from its formation to the mature structure. The SA node is part of the cardiac conduction system that controls the timing of heart muscle contraction. It relays electrical signals to the AV node. + GOC:mtg_heart + + + + + SA node development + GOC:mtg_heart + + + + + SAN development + GOC:BHF + GOC:mtg_cardiac_conduct_nov11 + + + + + sinus node development + GOC:BHF + GOC:mtg_cardiac_conduct_nov11 + - + - + - + - - + + - - - + + - regulation of respiratory gaseous exchange + The process whose specific outcome is the progression of the His-Purkinje system over time, from its formation to the mature structure. The His-Purkinje system receives signals from the AV node and is composed of the fibers that regulate cardiac muscle contraction in the ventricles. + dph + 2009-10-01T02:07:12Z + biological_process + GO:0003164 + His-Purkinje system development + + + + The process whose specific outcome is the progression of the His-Purkinje system over time, from its formation to the mature structure. The His-Purkinje system receives signals from the AV node and is composed of the fibers that regulate cardiac muscle contraction in the ventricles. + GOC:mtg_heart + - + - - - skin development - - - - - - - - - cellular amide metabolic process - - - - - - - - - - amide biosynthetic process - - - - - - - - - keratinocyte proliferation - - - - - - - - - dicarboxylic acid metabolic process - - - - - - - - - - detection of pheromone - - - - - - - - - glucan metabolic process - - - - - - - + - + - - + + - - - + + - regulation of system process + The process whose specific outcome is the progression of a Purkinje myocyte over time, from its formation to the mature structure. The Purkinje myocyte (also known as cardiac Purkinje fiber) is part of the cardiac conduction system that receives signals from the bundle of His and innervates the ventricular cardiac muscle. + dph + 2009-10-01T02:07:50Z + cardiac Purkinje fiber development + biological_process + GO:0003165 + Purkinje myocyte development + + + + The process whose specific outcome is the progression of a Purkinje myocyte over time, from its formation to the mature structure. The Purkinje myocyte (also known as cardiac Purkinje fiber) is part of the cardiac conduction system that receives signals from the bundle of His and innervates the ventricular cardiac muscle. + GOC:mtg_cardiac_conduct_nov11 + GOC:mtg_heart + - + - + - + - - + + - - - + + - regulation of digestive system process + The process whose specific outcome is the progression of the bundle of His over time, from its formation to the mature structure. The bundle of His is part of the His-Purkinje system that transmits signals from the AV node to the cardiac Purkinje fibers. + dph + 2009-10-01T02:08:43Z + atrioventricular bundle development + biological_process + GO:0003166 + bundle of His development + + + + The process whose specific outcome is the progression of the bundle of His over time, from its formation to the mature structure. The bundle of His is part of the His-Purkinje system that transmits signals from the AV node to the cardiac Purkinje fibers. + GOC:mtg_heart + + + + + atrioventricular bundle development + GOC:mtg_heart + - + - + - + - - + + - + - - + + - regulation of endocrine process + The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a Purkinje myocyte (also known as cardiac Purkinje fiber cell). These cells are specialized cardiomyocytes that receive signals from the bundle of His and innervate the ventricular cardiac muscle. + dph + 2009-10-01T02:49:54Z + cardiac Purkinje fiber cell differentiation + biological_process + GO:0003168 + Purkinje myocyte differentiation + + + + The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a Purkinje myocyte (also known as cardiac Purkinje fiber cell). These cells are specialized cardiomyocytes that receive signals from the bundle of His and innervate the ventricular cardiac muscle. + GOC:mtg_cardiac_conduct_nov11 + GOC:mtg_heart + - + - + - + - - + + - - - - - - - - - regulation of excretion + + + The process in which the anatomical structures of veins of the heart are generated and organized. + dph + 2009-10-08T10:45:41Z + biological_process + GO:0003169 + coronary vein morphogenesis + + + + The process in which the anatomical structures of veins of the heart are generated and organized. + GOC:mtg_heart + - + - + - + - - + + - - + + - - + + - regulation of respiratory system process + The progression of a heart valve over time, from its formation to the mature structure. A heart valve is a structure that restricts the flow of blood to different regions of the heart and forms from an endocardial cushion. + dph + 2009-10-08T10:50:09Z + cardiac valve development + biological_process + GO:0003170 + heart valve development + + + + The progression of a heart valve over time, from its formation to the mature structure. A heart valve is a structure that restricts the flow of blood to different regions of the heart and forms from an endocardial cushion. + GOC:mtg_heart + + + + + cardiac valve development + GOC:mtg_heart + - + - + - + - - + + - - - - - - - - regulation of anion transport + + The progression of the atrioventricular valve over time, from its formation to the mature structure. + dph + 2009-10-08T11:14:21Z + AV valve development + biological_process + GO:0003171 + atrioventricular valve development + + + + The progression of the atrioventricular valve over time, from its formation to the mature structure. + GOC:mtg_heart + + + + + AV valve development + GOC:mah + - + - + - + - - + + - - - - - - - - negative regulation of molecular function + + The progression of the sinoatrial valve over time, from its formation to the mature structure. + dph + 2009-10-08T11:15:39Z + SA valve development + biological_process + GO:0003172 + sinoatrial valve development + + + + The progression of the sinoatrial valve over time, from its formation to the mature structure. + GOC:mtg_heart + + + + + SA valve development + GOC:mah + - + - + - + - - + + - - - - - - - - positive regulation of molecular function - - - - - - - - - - cellular amine metabolic process - - - - - - - - - - cellular metabolic process - - - - - - - - - primary metabolic process - - - - - - - - - - - cellular polysaccharide catabolic process - - - - - - - - - - cellular catabolic process - - - - - - - - - - cellular biosynthetic process - - - - - - - - - - cellular macromolecule metabolic process - - - - - - - - - - cellular carbohydrate metabolic process - - - - - - - - - - - cellular polysaccharide metabolic process - - - - - - - - - - cellular nitrogen compound biosynthetic process - - - - - - - - - - - cellular carbohydrate catabolic process - - - - - - - - - small molecule metabolic process - - - - - - - - - - small molecule biosynthetic process + + The progression of the ventriculo bulbo valve over time, from its formation to the mature structure. + dph + 2009-10-08T11:16:25Z + biological_process + GO:0003173 + ventriculo bulbo valve development + + + + The progression of the ventriculo bulbo valve over time, from its formation to the mature structure. + GOC:mtg_heart + - + - - - cell body + + + + + + + + + + + + + + The progression of the mitral valve over time, from its formation to the mature structure. + dph + 2009-10-08T11:17:22Z + biological_process + GO:0003174 + mitral valve development + + + + The progression of the mitral valve over time, from its formation to the mature structure. + GOC:mtg_heart + - + - - - dentate gyrus mossy fiber + + + + + + + + + + + + + + The progression of the tricuspid valve over time, from its formation to the mature structure. + dph + 2009-10-08T11:18:12Z + biological_process + GO:0003175 + tricuspid valve development + + + + The progression of the tricuspid valve over time, from its formation to the mature structure. + GOC:mtg_heart + - + - - - - multi-organism reproductive process + + + + + + + + + + + + + + The progression of the aortic valve over time, from its formation to the mature structure. + dph + 2009-10-08T11:18:55Z + biological_process + GO:0003176 + aortic valve development + + + + The progression of the aortic valve over time, from its formation to the mature structure. + GOC:mtg_heart + - + - - - - multi-multicellular organism process + + + + + + + + + + + + + + The progression of the pulmonary valve over time, from its formation to the mature structure. + dph + 2009-10-08T11:19:44Z + biological_process + GO:0003177 + pulmonary valve development + + + + The progression of the pulmonary valve over time, from its formation to the mature structure. + GOC:mtg_heart + - + - - - biological phase + + + + + + + + + + + + + + The progression of the valve of the coronary sinus over time, from its formation to the mature structure. + dph + 2009-10-08T11:21:43Z + biological_process + GO:0003178 + coronary sinus valve development + + + + The progression of the valve of the coronary sinus over time, from its formation to the mature structure. + GOC:mtg_heart + - + - - + + + + + + + + + + + + + + - + - T cell selection - - - - - - - - - keratin filament - - - - - - - - - intermediate filament cytoskeleton + The process in which the structure of a heart valve is generated and organized. + dph + 2009-10-08T11:23:48Z + heart valve remodeling + heart valve remodelling + biological_process + GO:0003179 + heart valve morphogenesis + + + + The process in which the structure of a heart valve is generated and organized. + GOC:mtg_heart + + + + + heart valve remodeling + GOC:vk + GOC:yaf + + + + + heart valve remodelling + GOC:vk + GOC:yaf + - + - - - - - - - - + + + + + + + + + + + + + - + - development of primary sexual characteristics - - - - - - - - - - establishment of protein localization + The process in which the structure of the aortic valve is generated and organized. + dph + 2009-10-08T11:29:42Z + biological_process + GO:0003180 + aortic valve morphogenesis + + + + The process in which the structure of the aortic valve is generated and organized. + GOC:mtg_heart + - + - + - + - - + + - + - - + + - regulation of circadian sleep/wake cycle, sleep + The process in which the structure of the atrioventricular valve is generated and organized. + dph + 2009-10-08T11:31:59Z + AV valve morphogenesis + biological_process + GO:0003181 + atrioventricular valve morphogenesis + + + + The process in which the structure of the atrioventricular valve is generated and organized. + GOC:mtg_heart + + + + + AV valve morphogenesis + GOC:mah + - + - + - + - - + + - + - - + + - regulation of circadian sleep/wake cycle, non-REM sleep - - - - - - - - - external encapsulating structure organization - - - - - - - - - - leukocyte activation - - - - - - - - - - - juvenile hormone secretion + The process in which the structure of the coronary sinus valve is generated and organized. + dph + 2009-10-08T11:33:31Z + biological_process + GO:0003182 + coronary sinus valve morphogenesis + + + + The process in which the structure of the coronary sinus valve is generated and organized. + GOC:mtg_heart + - + - + - + - - + + - - + - - + + - regulation of B cell differentiation + The process in which the structure of the mitral valve is generated and organized. + dph + 2009-10-08T12:02:01Z + biological_process + GO:0003183 + mitral valve morphogenesis + + + + The process in which the structure of the mitral valve is generated and organized. + GOC:mtg_heart + - + - + - + - - + + - - - + - - + + - negative regulation of B cell differentiation + The process in which the structure of the pulmonary valve is generated and organized. + dph + 2009-10-08T12:03:35Z + biological_process + GO:0003184 + pulmonary valve morphogenesis + + + + The process in which the structure of the pulmonary valve is generated and organized. + GOC:mtg_heart + - + - + - + - - + + - - - + - - + + - positive regulation of B cell differentiation + The process in which the structure of the sinoatrial valve is generated and organized. + dph + 2009-10-08T12:04:52Z + SA valve morphogenesis + biological_process + GO:0003185 + sinoatrial valve morphogenesis + + + + The process in which the structure of the sinoatrial valve is generated and organized. + GOC:mtg_heart + + + + + SA valve morphogenesis + GOC:mah + - + - + - + - - + + - - + - - + + - regulation of T cell differentiation + The process in which the structure of the tricuspid valve is generated and organized. + dph + 2009-10-08T12:05:45Z + biological_process + GO:0003186 + tricuspid valve morphogenesis + + + + The process in which the structure of the tricuspid valve is generated and organized. + GOC:mtg_heart + - + - + - + - - + + - - - + - - + + - negative regulation of T cell differentiation + The process in which the structure of the ventriculo bulbo valve is generated and organized. + dph + 2009-10-08T12:07:00Z + biological_process + GO:0003187 + ventriculo bulbo valve morphogenesis + + + + The process in which the structure of the ventriculo bulbo valve is generated and organized. + GOC:mtg_heart + - + - + - + - - + + - - - + + - - + + - positive regulation of T cell differentiation + The developmental process pertaining to the initial formation of a heart valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. + dph + 2009-10-08T12:20:15Z + biological_process + GO:0003188 + heart valve formation + + + + The developmental process pertaining to the initial formation of a heart valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. + GOC:mtg_heart + - + - + - + - - + + - - + - - + + - regulation of cell differentiation + The developmental process pertaining to the initial formation of the aortic valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. + dph + 2009-10-08T01:05:44Z + biological_process + GO:0003189 + aortic valve formation + + + + The developmental process pertaining to the initial formation of the aortic valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. + GOC:mtg_heart + - + - + - + - - + + - - - + - - + + - negative regulation of cell differentiation + The developmental process pertaining to the initial formation of the atrioventricular valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. + dph + 2009-10-08T01:07:28Z + AV valve formation + biological_process + GO:0003190 + atrioventricular valve formation + + + + The developmental process pertaining to the initial formation of the atrioventricular valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. + GOC:mtg_heart + + + + + AV valve formation + GOC:mah + - + - + - + - - + + - - - + - - + + - positive regulation of cell differentiation + The developmental process pertaining to the initial formation of the coronary sinus valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. + dph + 2009-10-08T01:09:04Z + biological_process + GO:0003191 + coronary sinus valve formation + + + + The developmental process pertaining to the initial formation of the coronary sinus valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. + GOC:mtg_heart + - + - + - + - - + + - - + - - + + - regulation of epidermal cell differentiation + The developmental process pertaining to the initial formation of the mitral valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. + dph + 2009-10-08T01:10:19Z + biological_process + GO:0003192 + mitral valve formation + + + + The developmental process pertaining to the initial formation of the mitral valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. + GOC:mtg_heart + - + - + - + - - + + - - - + - - + + - negative regulation of epidermal cell differentiation + The developmental process pertaining to the initial formation of the pulmonary valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. + dph + 2009-10-08T01:11:20Z + biological_process + GO:0003193 + pulmonary valve formation + + + + The developmental process pertaining to the initial formation of the pulmonary valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. + GOC:mtg_heart + - + - + - + - - + + - - - + - - + + - positive regulation of epidermal cell differentiation + The developmental process pertaining to the initial formation of the sinoatrial valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. + dph + 2009-10-08T01:12:45Z + SA valve formation + biological_process + GO:0003194 + sinoatrial valve formation + + + + The developmental process pertaining to the initial formation of the sinoatrial valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. + GOC:mtg_heart + + + + + SA valve formation + GOC:mah + - + - + - + - - + + - + - - + + - regulation of keratinocyte differentiation + The developmental process pertaining to the initial formation of the tricuspid valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. + dph + 2009-10-08T01:14:40Z + biological_process + GO:0003195 + tricuspid valve formation + + + + The developmental process pertaining to the initial formation of the tricuspid valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. + GOC:mtg_heart + - + - + - + - - + + - - - + - - + + - negative regulation of keratinocyte differentiation + The developmental process pertaining to the initial formation of the ventriculo bulbo valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. + dph + 2009-10-08T01:16:02Z + biological_process + GO:0003196 + ventriculo bulbo valve formation + + + + The developmental process pertaining to the initial formation of the ventriculo bulbo valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. + GOC:mtg_heart + - + - + - + - - + + - - - + - - + + - positive regulation of keratinocyte differentiation + The progression of a cardiac cushion over time, from its initial formation to the mature structure. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves. + dph + 2009-10-08T01:17:43Z + biological_process + GO:0003197 + endocardial cushion development + + + + The progression of a cardiac cushion over time, from its initial formation to the mature structure. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves. + GOC:mtg_heart + - + - + - + - - + + - - + - - + + - regulation of lymphocyte differentiation + + + + + + + The process in which the anatomical structure of the endocardial cushion is generated and organized. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves. + dph + 2009-10-08T01:43:22Z + biological_process + GO:0003203 + endocardial cushion morphogenesis + + + + The process in which the anatomical structure of the endocardial cushion is generated and organized. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves. + GOC:mtg_heart + - + - + - + - - + + - - - + - - + + - negative regulation of lymphocyte differentiation + The progression of the cardiac skeleton over time, from its formation to the mature structure. The cardiac skeleton is a specialized extracellular matrix that separates the atria from the ventricles and provides physical support for the heart. + dph + 2009-10-13T09:05:04Z + heart fibrous skeleton development + biological_process + GO:0003204 + cardiac skeleton development + + + + The progression of the cardiac skeleton over time, from its formation to the mature structure. The cardiac skeleton is a specialized extracellular matrix that separates the atria from the ventricles and provides physical support for the heart. + GOC:mtg_heart + + + + + heart fibrous skeleton development + GOC:mtg_heart + - + - + - + - - + + - - - + + - - + + - positive regulation of lymphocyte differentiation + The progression of a cardiac chamber over time, from its formation to the mature structure. A cardiac chamber is an enclosed cavity within the heart. + dph + 2009-10-13T09:11:18Z + biological_process + GO:0003205 + cardiac chamber development + + + + The progression of a cardiac chamber over time, from its formation to the mature structure. A cardiac chamber is an enclosed cavity within the heart. + GOC:mtg_heart + - + - + - + - - + + - + + - - + + - regulation of epidermis development + + + + + + + The process in which a cardiac chamber is generated and organized. A cardiac chamber is an enclosed cavity within the heart. + dph + 2009-10-13T09:14:51Z + heart chamber morphogenesis + biological_process + GO:0003206 + cardiac chamber morphogenesis + + + + The process in which a cardiac chamber is generated and organized. A cardiac chamber is an enclosed cavity within the heart. + GOC:mtg_heart + + + + + heart chamber morphogenesis + GOC:mtg_heart + - + - + - + - - + + - - + + - - + + - negative regulation of epidermis development + The developmental process pertaining to the initial formation of a cardiac chamber from unspecified parts. A cardiac chamber is an enclosed cavity within the heart. + dph + 2009-10-13T09:29:13Z + heart chamber formation + biological_process + GO:0003207 + cardiac chamber formation + + + + The developmental process pertaining to the initial formation of a cardiac chamber from unspecified parts. A cardiac chamber is an enclosed cavity within the heart. + GOC:mtg_heart + + + + + heart chamber formation + GOC:mtg_heart + - + - + - + - - + + - - + - - + + - positive regulation of epidermis development + The process in which the cardiac ventricle is generated and organized. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart. + dph + 2009-10-13T09:38:44Z + biological_process + GO:0003208 + cardiac ventricle morphogenesis + + + + The process in which the cardiac ventricle is generated and organized. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart. + GOC:mtg_heart + - + - + - + - - + + - - - + - - + + - negative regulation of glycogen biosynthetic process + The process in which the cardiac atrium is generated and organized. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle. + dph + 2009-10-13T09:39:44Z + biological_process + GO:0003209 + cardiac atrium morphogenesis + + + + The process in which the cardiac atrium is generated and organized. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle. + GOC:mtg_heart + - + - + - + - - + + - - - - + - - + + - positive regulation of glycogen biosynthetic process + The developmental process pertaining to the initial formation of a cardiac atrium from unspecified parts. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle. + dph + 2009-10-13T09:44:25Z + biological_process + GO:0003210 + cardiac atrium formation + + + + The developmental process pertaining to the initial formation of a cardiac atrium from unspecified parts. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle. + GOC:mtg_heart + - + - + - + - - + + - - - + - - + + - negative regulation of cellular amino acid metabolic process + The developmental process pertaining to the initial formation of a cardiac ventricle from unspecified parts. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart. + dph + 2009-10-13T09:46:27Z + biological_process + GO:0003211 + cardiac ventricle formation + + + + The developmental process pertaining to the initial formation of a cardiac ventricle from unspecified parts. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart. + GOC:mtg_heart + - + - + - + - - + + - - - - - - - - - - positive regulation of cellular amino acid metabolic process + + The process in which the left cardiac atrium is generated and organized. + dph + 2009-10-13T09:48:16Z + biological_process + GO:0003212 + cardiac left atrium morphogenesis + + + + The process in which the left cardiac atrium is generated and organized. + GOC:mtg_heart + - + - + - + - - + + - - - - - - - - - regulation of angiogenesis + + The process in which the right cardiac atrium is generated and organized. + dph + 2009-10-13T09:49:03Z + biological_process + GO:0003213 + cardiac right atrium morphogenesis + + + + The process in which the right cardiac atrium is generated and organized. + GOC:mtg_heart + - + - + - + - - + + - - - - - - - - - positive regulation of angiogenesis + + The process in which the left cardiac ventricle is generated and organized. + dph + 2009-10-13T09:50:08Z + biological_process + GO:0003214 + cardiac left ventricle morphogenesis + + + + The process in which the left cardiac ventricle is generated and organized. + GOC:mtg_heart + - + - + - + - - + + - - - - - - - - - positive regulation of ossification + + The process in which the right cardiac ventricle is generated and organized. + dph + 2009-10-13T09:50:57Z + biological_process + GO:0003215 + cardiac right ventricle morphogenesis + + + + The process in which the right cardiac ventricle is generated and organized. + GOC:mtg_heart + - + - + - + - - + + - - + - - + + - positive regulation of cell adhesion + The developmental process pertaining to the initial formation of a left cardiac atrium from unspecified parts. + dph + 2009-10-13T09:52:31Z + biological_process + GO:0003216 + cardiac left atrium formation + + + + The developmental process pertaining to the initial formation of a left cardiac atrium from unspecified parts. + GOC:mtg_heart + - + - + - + - - + + - - + - - + + - negative regulation of cell cycle + The developmental process pertaining to the initial formation of a cardiac right atrium from unspecified parts. + dph + 2009-10-13T09:53:12Z + biological_process + GO:0003217 + cardiac right atrium formation + + + + The developmental process pertaining to the initial formation of a cardiac right atrium from unspecified parts. + GOC:mtg_heart + - + - + - + - - + + - - + - - + + - positive regulation of cell cycle + The developmental process pertaining to the initial formation of a left cardiac ventricle from unspecified parts. + dph + 2009-10-13T09:54:33Z + biological_process + GO:0003218 + cardiac left ventricle formation + + + + The developmental process pertaining to the initial formation of a left cardiac ventricle from unspecified parts. + GOC:mtg_heart + - + - + - + - - + + - - - + - - + + - negative regulation of glycogen catabolic process + The developmental process pertaining to the initial formation of a right cardiac ventricle from unspecified parts. + dph + 2009-10-13T09:55:38Z + biological_process + GO:0003219 + cardiac right ventricle formation + + + + The developmental process pertaining to the initial formation of a right cardiac ventricle from unspecified parts. + GOC:mtg_heart + - + - + - + - - + + - - - + - - + + - positive regulation of glycogen catabolic process + The process in which the anatomical structures of left cardiac ventricle muscle are generated and organized. + dph + 2009-10-13T10:18:05Z + left ventricular myocardium morphogenesis + biological_process + GO:0003220 + left ventricular cardiac muscle tissue morphogenesis + + + + The process in which the anatomical structures of left cardiac ventricle muscle are generated and organized. + GOC:mtg_heart + + + + + left ventricular myocardium morphogenesis + GOC:mtg_heart + - + - + - + - - + + - - + - - + + - negative regulation of heart contraction + The process in which the anatomical structures of the right cardiac ventricle muscle are generated and organized. + dph + 2009-10-13T10:26:33Z + right ventricle myocardium morphogenesis + biological_process + GO:0003221 + right ventricular cardiac muscle tissue morphogenesis + + + + The process in which the anatomical structures of the right cardiac ventricle muscle are generated and organized. + GOC:mtg_heart + + + + + right ventricle myocardium morphogenesis + GOC:mtg_heart + - + - + - + - - + + - - - - - - - - - positive regulation of heart contraction + + + The process in which the anatomical structures of the trabecular cardiac ventricle muscle are generated and organized. + dph + 2009-10-13T10:33:00Z + biological_process + trabecula carnea morphogenesis + GO:0003222 + ventricular trabecula myocardium morphogenesis + + + + The process in which the anatomical structures of the trabecular cardiac ventricle muscle are generated and organized. + GOC:mtg_heart + + + + + trabecula carnea morphogenesis + GOC:dph + - + - + - + - - + + - - - - - - - - - negative regulation of lipid metabolic process + + The process in which the anatomical structures of the compact cardiac ventricle muscle are generated and organized. + dph + 2009-10-13T10:34:21Z + biological_process + GO:0003223 + ventricular compact myocardium morphogenesis + + + + The process in which the anatomical structures of the compact cardiac ventricle muscle are generated and organized. + GOC:mtg_heart + - + - + - + - - + + - - - - - - - - - positive regulation of lipid metabolic process + + + The process in which the anatomical structures of cardiac left ventricular compact myocardium are generated and organized. + dph + 2009-10-13T10:43:36Z + biological_process + GO:0003224 + left ventricular compact myocardium morphogenesis + + + + The process in which the anatomical structures of cardiac left ventricular compact myocardium are generated and organized. + GOC:mtg_heart + - + - + - + - - + + - - - - - - - - - - - negative regulation of meiotic nuclear division + + + The process in which the anatomical structures of cardiac left ventricular trabecular myocardium are generated and organized. + dph + 2009-10-13T10:45:09Z + biological_process + GO:0003225 + left ventricular trabecular myocardium morphogenesis + + + + The process in which the anatomical structures of cardiac left ventricular trabecular myocardium are generated and organized. + GOC:mtg_heart + - + - + - + - - + + - - - - - - - - - - - positive regulation of meiotic nuclear division + + + The process in which the anatomical structures of the right ventricular compact myocardium are generated and organized. + dph + 2009-10-13T10:48:42Z + biological_process + GO:0003226 + right ventricular compact myocardium morphogenesis + + + + The process in which the anatomical structures of the right ventricular compact myocardium are generated and organized. + GOC:mtg_heart + - + - + - + - - + + - - - - - - - - - negative regulation of carbohydrate metabolic process + + + The process in which the anatomical structures of the right ventricular myocardium are generated and organized. + dph + 2009-10-13T10:50:59Z + biological_process + GO:0003227 + right ventricular trabecular myocardium morphogenesis + + + + The process in which the anatomical structures of the right ventricular myocardium are generated and organized. + GOC:mtg_heart + - + - + - + - - + + - - - - - - - - - positive regulation of carbohydrate metabolic process + The process whose specific outcome is the progression of cardiac muscle of the atrium over time, from its formation to the mature structure. + https://github.com/geneontology/go-ontology/issues/22614 + dph + 2009-10-13T10:53:18Z + atrial myocardium development + biological_process + GO:0003228 + atrial cardiac muscle tissue development + + + + The process whose specific outcome is the progression of cardiac muscle of the atrium over time, from its formation to the mature structure. + GOC:mtg_heart + + + + + atrial myocardium development + GOC:mtg_heart + - + - + - + - - + + - - - - - - - - - negative regulation of catecholamine metabolic process + The process whose specific outcome is the progression of ventricular cardiac muscle over time, from its formation to the mature structure. + dph + 2009-10-13T10:56:01Z + ventricular myocardium development + biological_process + GO:0003229 + ventricular cardiac muscle tissue development + + + + The process whose specific outcome is the progression of ventricular cardiac muscle over time, from its formation to the mature structure. + GOC:mtg_heart + + + + + ventricular myocardium development + GOC:mtg_heart + - + - + - + - - + + - - - - - - - - - positive regulation of catecholamine metabolic process + + The process whose specific outcome is the progression of a cardiac atrium over time, from its formation to the mature structure. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle. + dph + 2009-10-13T11:02:07Z + biological_process + GO:0003230 + cardiac atrium development + + + + The process whose specific outcome is the progression of a cardiac atrium over time, from its formation to the mature structure. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle. + GOC:mtg_heart + - + - + - + - - + + - - - - - - - - - negative regulation of exocytosis + + The process whose specific outcome is the progression of a cardiac ventricle over time, from its formation to the mature structure. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart. + dph + 2009-10-13T11:03:16Z + biological_process + GO:0003231 + cardiac ventricle development + + + + The process whose specific outcome is the progression of a cardiac ventricle over time, from its formation to the mature structure. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart. + GOC:mtg_heart + - + - + - + - - + + - - - - - - - - - positive regulation of exocytosis + + The process whose specific outcome is the progression of the bulbus arteriosus over time, from its formation to the mature structure. The bulbus arteriosus is an elastic heart chamber. + dph + 2009-10-13T11:05:36Z + biological_process + GO:0003232 + bulbus arteriosus development + + + + The process whose specific outcome is the progression of the bulbus arteriosus over time, from its formation to the mature structure. The bulbus arteriosus is an elastic heart chamber. + GOC:mtg_heart + - + - + - + - - + + - - + - - + + - negative regulation of growth + The process in which the bulbus arteriosus is generated and organized. The bulbus arteriosus is an elastic cardiac chamber. + dph + 2009-10-13T11:07:30Z + biological_process + GO:0003233 + bulbus arteriosus morphogenesis + + + + The process in which the bulbus arteriosus is generated and organized. The bulbus arteriosus is an elastic cardiac chamber. + GOC:mtg_heart + - + - + - + - - + + - - + - - + + - positive regulation of growth + The developmental process pertaining to the initial formation of the bulbus arteriosus from unspecified parts. The bulbus arteriosus is an elastic chamber of the heart. + dph + 2009-10-13T11:10:02Z + biological_process + GO:0003234 + bulbus arteriosus formation + + + + The developmental process pertaining to the initial formation of the bulbus arteriosus from unspecified parts. The bulbus arteriosus is an elastic chamber of the heart. + GOC:mtg_heart + - + - + - + - - + + - - - - - - - - - negative regulation of muscle contraction + + The progression of the sinus venosus over time, from its formation to the mature structure. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart. + dph + 2009-10-13T11:12:34Z + biological_process + GO:0003235 + sinus venosus development + + + + The progression of the sinus venosus over time, from its formation to the mature structure. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart. + GOC:mtg_heart + - + - + - + - - + + - - + - - + + - positive regulation of muscle contraction + The process in which the sinus venosus is generated and organized. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart. + dph + 2009-10-13T11:16:52Z + biological_process + GO:0003236 + sinus venosus morphogenesis + + + + The process in which the sinus venosus is generated and organized. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart. + GOC:mtg_heart + - + - + - + - - + + - - - - + - - + + - positive regulation of circadian sleep/wake cycle, sleep + The developmental process pertaining to the initial formation of the sinus venosus from unspecified parts. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart. + dph + 2009-10-13T11:18:34Z + biological_process + GO:0003237 + sinus venosus formation + + + + The developmental process pertaining to the initial formation of the sinus venosus from unspecified parts. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart. + GOC:mtg_heart + - + - + - + - - + + - - - - - - - - - negative regulation of steroid metabolic process + + The progression of the conus arteriosus over time, from its formation to the mature structure. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk. + dph + 2009-10-13T11:20:57Z + biological_process + GO:0003238 + conus arteriosus development + + + + The progression of the conus arteriosus over time, from its formation to the mature structure. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk. + GOC:mtg_heart + - + - + - + - - + + - - + - - + + - positive regulation of steroid metabolic process + The process in which the conus arteriosus is generated and organized. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk. + dph + 2009-10-13T11:25:04Z + biological_process + GO:0003239 + conus arteriosus morphogenesis + + + + The process in which the conus arteriosus is generated and organized. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk. + GOC:mtg_heart + - + - + - + - - + + - - - - + - - + + - negative regulation of juvenile hormone secretion + The developmental process pertaining to the initial formation of the conus arteriosus from unspecified parts. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk. + dph + 2009-10-13T11:25:47Z + biological_process + GO:0003240 + conus arteriosus formation + + + + The developmental process pertaining to the initial formation of the conus arteriosus from unspecified parts. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk. + GOC:mtg_heart + - + - + - + - - + + - - - + - - + + - positive regulation of juvenile hormone secretion + Developmental growth that contributes to the shaping of the heart. + dph + 2009-10-13T11:28:46Z + biological_process + GO:0003241 + growth involved in heart morphogenesis + + + + Developmental growth that contributes to the shaping of the heart. + GOC:mtg_heart + - + - + - + - - + + - - - - + + - negative regulation of smooth muscle contraction + The developmental growth of cardiac muscle tissue that contributes to the shaping of the heart. + dph + 2009-10-13T11:44:21Z + biological_process + GO:0003245 + cardiac muscle tissue growth involved in heart morphogenesis + + + + The developmental growth of cardiac muscle tissue that contributes to the shaping of the heart. + GOC:mtg_heart + - + - + - + - - + + - - + - - + + - positive regulation of smooth muscle contraction + + + + + + + The increase in heart capillaries that accompanies physiological hypertrophy of cardiac muscle. + dph + 2009-10-13T11:53:12Z + biological_process + GO:0003248 + heart capillary growth + + + + The increase in heart capillaries that accompanies physiological hypertrophy of cardiac muscle. + GOC:mtg_heart + - + - + + + + + + + + + + + + + + The multiplication or reproduction of cells that contributes to the shaping of a heart valve. + dph + 2009-10-13T01:59:19Z + biological_process + GO:0003249 + cell proliferation involved in heart valve morphogenesis + + + + + The multiplication or reproduction of cells that contributes to the shaping of a heart valve. + GOC:mtg_heart + + + + + + + - - + + - - - - - - - - - negative regulation of striated muscle contraction + Any process that modulates the rate, frequency or extent of cell proliferation that contributes to the shaping of a heart valve. + dph + 2009-10-13T02:03:42Z + biological_process + GO:0003250 + regulation of cell proliferation involved in heart valve morphogenesis + + + + Any process that modulates the rate, frequency or extent of cell proliferation that contributes to the shaping of a heart valve. + GOC:mtg_heart + - + - + - + - - - - - - - - - positive regulation of striated muscle contraction + Any process that increases the rate, frequency or extent of cell proliferation that contributes to the shaping of a heart valve. + dph + 2009-10-13T02:07:20Z + biological_process + GO:0003251 + positive regulation of cell proliferation involved in heart valve morphogenesis + + + + Any process that increases the rate, frequency or extent of cell proliferation that contributes to the shaping of a heart valve. + GOC:mtg_heart + - + - + - + - - - - - - - - - - negative regulation of embryonic development + Any process that decreases the rate, frequency or extent of cell proliferation that contributes to the shaping of a heart valve. + dph + 2009-10-13T02:10:39Z + biological_process + GO:0003252 + negative regulation of cell proliferation involved in heart valve morphogenesis + + + + Any process that decreases the rate, frequency or extent of cell proliferation that contributes to the shaping of a heart valve. + GOC:mtg_heart + - + - + - + - - + + - - - + + - regulation of embryonic development + The orderly movement of a neural crest cell from one site to another that will contribute to the morphogenesis of the outflow tract. + dph + 2009-10-13T02:14:16Z + biological_process + GO:0003253 + cardiac neural crest cell migration involved in outflow tract morphogenesis + + + + The orderly movement of a neural crest cell from one site to another that will contribute to the morphogenesis of the outflow tract. + GOC:mtg_heart + - + - + - + - - + + - - + + - - + + - positive regulation of circadian sleep/wake cycle, non-REM sleep + The developmental process pertaining to the initial formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves. + dph + 2009-10-20T08:53:19Z + biological_process + GO:0003272 + endocardial cushion formation + + + + The developmental process pertaining to the initial formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves. + GOC:mtg_heart + PMID:15797462 + - + - - - - - alcohol biosynthetic process - - - - - - - - - - - aldehyde biosynthetic process + + + + + + + + + + + + + The orderly movement of a cell from one site to another that will contribute to the formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves. + dph + 2009-10-20T09:08:44Z + biological_process + GO:0003273 + cell migration involved in endocardial cushion formation + + + + The orderly movement of a cell from one site to another that will contribute to the formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves. + GOC:mtg_heart + - + - - - - carboxylic acid biosynthetic process + + + + + + + + + + + + + + + + + + + + + The progression of a cardiac septum over time, from its initial formation to the mature structure. + dph + 2009-10-20T09:45:13Z + heart septum development + biological_process + GO:0003279 + cardiac septum development + + + + The progression of a cardiac septum over time, from its initial formation to the mature structure. + GOC:mtg_heart + + + + + heart septum development + GOC:mtg_heart + - + - - - heterocycle metabolic process + + + + + + + + + + + + + + + + + + + + The progression of the ventricular septum over time from its formation to the mature structure. + dph + 2009-10-20T10:04:51Z + interventricular septum development + septum inferius development + biological_process + GO:0003281 + ventricular septum development + + + + The progression of the ventricular septum over time from its formation to the mature structure. + GOC:mtg_heart + + + + + interventricular septum development + GOC:mtg_heart + + + + + septum inferius development + GOC:mtg_heart + - + - - - - - saliva secretion + + + + + + + + + + + + + + The progression of the ventricular septum intermedium over time, from its formation to the mature structure. + dph + 2009-10-20T10:09:53Z + biological_process + GO:0003282 + ventricular septum intermedium development + + + + The progression of the ventricular septum intermedium over time, from its formation to the mature structure. + GOC:mtg_heart + - + - - + + + + + + + + + + + + + - + - development of primary female sexual characteristics + The progression of the atrial septum over time, from its initial formation to the mature structure. + dph + 2009-10-20T10:10:38Z + biological_process + GO:0003283 + atrial septum development + + + + The progression of the atrial septum over time, from its initial formation to the mature structure. + GOC:mtg_heart + - + - - - lymphocyte activation + + + + + + + + + + + + + + The progression of the septum primum over time, from its formation to the mature structure. + dph + 2009-10-20T10:12:26Z + biological_process + GO:0003284 + septum primum development + + + + The progression of the septum primum over time, from its formation to the mature structure. + GOC:mtg_heart + - + - - - - lymphocyte proliferation + + + + + + + + + + + + + + The progression of the septum secundum over time, from its initial formation to the mature structure. + dph + 2009-10-20T10:21:13Z + biological_process + GO:0003285 + septum secundum development + + + + The progression of the septum secundum over time, from its initial formation to the mature structure. + GOC:mtg_heart + - + - - + + + + + + + + + + + + + + The progression of the atrial septum intermedium over time, from its formation to the mature structure. + dph + 2009-10-20T10:23:52Z + biological_process + GO:0003286 + atrial septum intermedium development + + + + + The progression of the atrial septum intermedium over time, from its formation to the mature structure. + GOC:mtg_heart + + + + + + + + + + + + + + + + + + + + The developmental process in which a ventricular septum intermedium is generated and organized. + dph + 2009-10-20T10:58:48Z + biological_process + GO:0003288 + ventricular septum intermedium morphogenesis + + + + + The developmental process in which a ventricular septum intermedium is generated and organized. + GOC:mtg_heart + + + + + + + + + + + + + + + + + + + - + - female sex differentiation + The process in which anatomical structure of an atrial septum primum is generated and organized. + dph + 2009-10-20T10:32:32Z + biological_process + GO:0003289 + atrial septum primum morphogenesis + + + + The process in which anatomical structure of an atrial septum primum is generated and organized. + GOC:mtg_heart + - + - + - + - - + + - - - + - - + + - negative regulation of insulin secretion + The process in which anatomical structure of an atrial septum secundum is generated and organized. + dph + 2009-10-20T10:33:57Z + biological_process + GO:0003290 + atrial septum secundum morphogenesis + + + + The process in which anatomical structure of an atrial septum secundum is generated and organized. + GOC:mtg_heart + - + - - - - + + + + + + + + + + + + + - + - sperm competition + The process in which anatomical structure of an atrial septum intermedium is generated and organized. + dph + 2009-10-20T10:35:04Z + biological_process + GO:0003291 + atrial septum intermedium morphogenesis + + + + The process in which anatomical structure of an atrial septum intermedium is generated and organized. + GOC:mtg_heart + - + - - - acid secretion + + + The enlargement or overgrowth of all or part of a muscle organ or tissue due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development. + dph + 2009-10-22T09:24:51Z + biological_process + GO:0003298 + physiological muscle hypertrophy + + + + The enlargement or overgrowth of all or part of a muscle organ or tissue due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development. + GOC:mtg_heart + - + - - - isoprenoid transport + + + The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division. + dph + 2009-10-22T10:33:56Z + biological_process + GO:0003300 + cardiac muscle hypertrophy + + + + The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division. + GOC:mtg_heart + - + - - - terpenoid transport + + + + + + + + + + The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division. This process contributes to the developmental growth of the heart. + dph + 2009-10-22T10:38:10Z + biological_process + GO:0003301 + physiological cardiac muscle hypertrophy + + + + The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division. This process contributes to the developmental growth of the heart. + GOC:BHF + GOC:mtg_cardiac_conduct_nov11 + GOC:mtg_heart + - + - + - + - - + + - - - + - - + + - regulation of saliva secretion + The progression of the heart rudiment over time, from its initial formation to the mature structure. The heart rudiment is a cone-like structure that is formed when myocardial progenitor cells of the heart field fuse at the midline. The heart rudiment is the first structure of the heart tube. + dph + 2009-10-27T08:32:40Z + heart cone development + biological_process + GO:0003313 + heart rudiment development + + + + The progression of the heart rudiment over time, from its initial formation to the mature structure. The heart rudiment is a cone-like structure that is formed when myocardial progenitor cells of the heart field fuse at the midline. The heart rudiment is the first structure of the heart tube. + GOC:mtg_heart + + + + + heart cone development + GOC:mtg_heart + - + - + - + - - + + - - - + + - - + + - positive regulation of saliva secretion - - - - - - - - - - hormone secretion + The process in which the anatomical structures of the heart rudiment are generated and organized. + dph + 2009-10-27T08:38:04Z + heart cone morphogenesis + biological_process + GO:0003314 + heart rudiment morphogenesis + + + + The process in which the anatomical structures of the heart rudiment are generated and organized. + GOC:mtg_heart + + + + + heart cone morphogenesis + GOC:mtg_heart + - + - + - + - - + + - - - - + + - - + + - regulation of hormone secretion + The developmental process pertaining to the initial formation of the heart rudiment. + dph + 2009-10-27T08:43:37Z + heart cone formation + biological_process + GO:0003315 + heart rudiment formation + + + + The developmental process pertaining to the initial formation of the heart rudiment. + GOC:mtg_heart + + + + + heart cone formation + GOC:mtg_heart + - + - + - + - - - - - - - - - regulation of hormone biosynthetic process + + + Any process that modulates the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells. + dph + 2009-11-02T02:07:40Z + biological_process + GO:0003330 + regulation of extracellular matrix constituent secretion + + + + Any process that modulates the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells. + GOC:dph + GOC:tb + - + - + - + - - - - - - - - - - positive regulation of hormone biosynthetic process + + + + Any process that increases the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells. + dph + 2009-11-02T02:11:22Z + biological_process + GO:0003331 + positive regulation of extracellular matrix constituent secretion + + + + Any process that increases the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells. + GOC:dph + GOC:tb + - + - + - - + + - - - - - - - - - - - positive regulation of hormone secretion + + + + Any process that decreases the rate, frequency, or extent the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells. + dph + 2009-11-02T02:13:49Z + biological_process + GO:0003332 + negative regulation of extracellular matrix constituent secretion + + + + Any process that decreases the rate, frequency, or extent the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells. + GOC:dph + GOC:tb + - + - + - + - - + + - - - - + - - + + - negative regulation of hormone secretion + The process whose specific outcome is the progression of a keratinocyte over time, from its formation to the mature structure. + dph + 2009-11-24T08:55:57Z + biological_process + GO:0003334 + keratinocyte development + + + + The process whose specific outcome is the progression of a keratinocyte over time, from its formation to the mature structure. + GOC:dph + - + - + - + - - + + - - - - - + + - positive regulation of lipid biosynthetic process + The process whose specific outcome is the progression of the corneocyte over time, from its formation to the mature structure. A corneocyte is the last stage of development of a keratinocyte where the keratinocyte flattens, loses its nucleus and eventually delaminates from the epidermis. + dph + 2009-11-24T09:01:02Z + biological_process + GO:0003335 + corneocyte development + + + + The process whose specific outcome is the progression of the corneocyte over time, from its formation to the mature structure. A corneocyte is the last stage of development of a keratinocyte where the keratinocyte flattens, loses its nucleus and eventually delaminates from the epidermis. + GOC:dph + - + - + - + - - + + - - - - + + - regulation of lipid biosynthetic process + A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros. + dph + 2009-11-24T09:29:49Z + biological_process + metanephric mesenchyme to epithelial transition + GO:0003337 + mesenchymal to epithelial transition involved in metanephros morphogenesis + + + + A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros. + GOC:dph + GOC:yaf + + + + + metanephric mesenchyme to epithelial transition + GOC:dph + - + - - - secretion - - + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the metanephros are generated and organized. + dph + 2009-11-24T09:32:09Z + biological_process + GO:0003338 + metanephros morphogenesis + + + + + The process in which the anatomical structures of the metanephros are generated and organized. + GOC:dph + GOC:yaf + + - + - - - carboxylic acid transport + + + + + + + + + + + + + Any process that modulates the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros. + dph + 2009-11-24T09:43:04Z + biological_process + GO:0003339 + regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis + + + + Any process that modulates the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros. + GOC:dph + - + - - - male gamete generation + + + + + + + + + + + + + Any process that decreases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros. + dph + 2009-11-24T09:46:12Z + biological_process + GO:0003340 + negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis + + + + Any process that decreases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros. + GOC:dph + GOC:yaf + - + - - - - + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + - - + + - sperm capacitation - - - - - - - - - - - norepinephrine secretion + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The directed, self-propelled movement of a cilium. + https://github.com/geneontology/go-ontology/issues/19809 + + + + + + + dph + 2009-11-24T09:56:26Z + GO:0036142 + microtubule-based flagellum movement + flagellar movement + flagellum movement + biological_process + ciliary motility + cilium beating + flagellar motility + GO:0003341 + Note that we deem cilium and microtubule-based flagellum to be equivalent. + cilium movement + + + + The directed, self-propelled movement of a cilium. + GOC:dph + GOC:jl + + + + + flagellar movement + GOC:bf + + + + + cilium beating + GOC:ascb_2009 + GOC:dph + GOC:tb + - + - - - organelle fusion + + + + + + + + + + + + + + + + + + + + The progression of the proepicardium from its formation to the mature structure. The proepicardium is an outpouching of the septum transversum. + dph + 2009-12-01T10:30:17Z + biological_process + GO:0003342 + proepicardium development + + + + The progression of the proepicardium from its formation to the mature structure. The proepicardium is an outpouching of the septum transversum. + GOC:dph + PMID:18722343 + - + - - - organelle fission + + + + + + + + + + + + + + The progression of the septum transversum from its initial formation to the mature structure. The septum transversum is a portion of the trunk mesenchyme. + dph + 2009-12-01T10:40:17Z + biological_process + GO:0003343 + septum transversum development + + + + The progression of the septum transversum from its initial formation to the mature structure. The septum transversum is a portion of the trunk mesenchyme. + GOC:dph + PMID:18722343 + - + - - + + + + + + + + + + + + + + - + - mesoderm morphogenesis + The process in which the anatomical structure of the pericardium is generated and organized. + dph + 2009-12-01T10:46:34Z + biological_process + GO:0003344 + pericardium morphogenesis + + + + The process in which the anatomical structure of the pericardium is generated and organized. + GOC:dph + PMID:18722343 + - + - - - + + + + + + + + + + + + - + - cell development + The progression of the pulmonary myocardium over time, from its initial formation to the mature structure. The pulmonary myocardium is the myocardial tissue present in the pulmonary vein. + dph + 2009-12-01T12:50:06Z + biological_process + GO:0003350 + pulmonary myocardium development + + + + The progression of the pulmonary myocardium over time, from its initial formation to the mature structure. The pulmonary myocardium is the myocardial tissue present in the pulmonary vein. + GOC:dph + PMID:17638577 + - + - - - - - - - - - - cell maturation - + + + + The directed, self-propelled movement of cilia of epithelial cells. Depending on the type of cell, there may be one or many cilia per cell. This movement is usually coordinated between many epithelial cells, and serves to move extracellular fluid. + dph + 2009-12-03T10:08:25Z + biological_process + cilium movement involved in fluid flow + epithelial cilium beating + GO:0003351 + epithelial cilium movement involved in extracellular fluid movement + + + + + The directed, self-propelled movement of cilia of epithelial cells. Depending on the type of cell, there may be one or many cilia per cell. This movement is usually coordinated between many epithelial cells, and serves to move extracellular fluid. + GOC:dph + GOC:krc + + + + + cilium movement involved in fluid flow + GOC:cilia + + + + + epithelial cilium beating + GOC:ascb_2009 + GOC:dph + GOC:tb + - + - - - - oogenesis + + + + + + + + + + + + + Any process that modulates the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium. + dph + 2009-12-03T10:12:00Z + GO:1900172 + regulation of microtubule-based flagellum movement + biological_process + regulation of flagellar movement + regulation of flagellum movement + GO:0003352 + Note that we deem cilium and microtubule-based flagellum to be equivalent. + regulation of cilium movement + + + + Any process that modulates the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium. + GOC:dph + + + + + regulation of flagellar movement + GOC:TermGenie + - + - - - rhythmic process + + + + + + + + + + + + + Any process that increases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium. + dph + 2009-12-03T10:16:10Z + GO:1900174 + positive regulation of microtubule-based flagellum movement + biological_process + positive regulation of flagellar movement + positive regulation of flagellum movement + GO:0003353 + Note that we deem cilium and microtubule-based flagellum to be equivalent. + positive regulation of cilium movement + + + + Any process that increases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium. + GOC:dph + + + + + positive regulation of flagellar movement + GOC:TermGenie + - + - - - - circadian behavior + + + + + + + + + + + + + Any process that decreases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium. + dph + 2009-12-03T10:17:47Z + GO:1900173 + negative regulation of microtubule-based flagellum movement + biological_process + negative regulation of flagellum movement + GO:0003354 + Note that we deem cilium and microtubule-based flagellum to be equivalent. + negative regulation of cilium movement + + + + Any process that decreases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium. + GOC:dph + - + - - - - - - - - - animal organ development + + + + + + + + + + + + + + The directed, self-propelled movement of cilia of inner ear epithelial cells, resulting the aggregation of otolith seed particles. + dph + 2009-12-03T10:21:08Z + biological_process + GO:0003355 + cilium movement involved in otolith formation + + + + The directed, self-propelled movement of cilia of inner ear epithelial cells, resulting the aggregation of otolith seed particles. + GOC:dph + GOC:krc + PMID:19043402 + - + - - - - - - - - - blood vessel morphogenesis + + + + + + + + + + + + + + + The progression of the brainstem from its formation to the mature structure. The brainstem is the part of the brain that connects the brain with the spinal cord. + dph + 2009-12-03T10:47:20Z + biological_process + GO:0003360 + brainstem development + + + + The progression of the brainstem from its formation to the mature structure. The brainstem is the part of the brain that connects the brain with the spinal cord. + GOC:dph + - + - - - - - - - - - - - spermatid differentiation + + + + + + + + + + + + + The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell. + dph + 2009-12-08T04:50:41Z + biological_process + GO:0003365 + establishment of cell polarity involved in ameboidal cell migration + + + + The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell. + GOC:ascb_2009 + GOC:dph + GOC:tb + - + - + - + - - + + - - - + + - positive regulation of biological process + Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell. + dph + 2009-12-08T05:42:46Z + biological_process + GO:0003371 + establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration + + + + Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell. + GOC:ascb_2009 + GOC:dph + GOC:tb + - + - + - + - - + + - - - - - - - - negative regulation of biological process + The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell taking part in gastrulation. + dph + 2009-12-09T06:54:44Z + biological_process + GO:0003379 + establishment of cell polarity involved in gastrulation cell migration + + + + The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell taking part in gastrulation. + GOC:ascb_2009 + GOC:dph + GOC:tb + - + - + - + - - + + - - - - + + - positive regulation of behavior + Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell taking part in gastrulation. + dph + 2009-12-09T07:10:57Z + biological_process + GO:0003380 + establishment or maintenance of cytoskeleton polarity involved in gastrulation + + + + Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell taking part in gastrulation. + GOC:ascb_2009 + GOC:dph + GOC:tb + - + - + - + - - + + - - - - - - - - - negative regulation of behavior + The change in form that occurs when an epithelial cell progresses from it initial formation to its mature state, contributing to the process of gastrulation. + dph + 2009-12-09T07:18:53Z + biological_process + GO:0003381 + epithelial cell morphogenesis involved in gastrulation + + + + The change in form that occurs when an epithelial cell progresses from it initial formation to its mature state, contributing to the process of gastrulation. + GOC:ascb_2009 + GOC:dph + GOC:tb + - + - + - + - - + + - - + - - + + - positive regulation of cellular process + The change in form that occurs when an epithelial cell progresses from its initial formation to its mature state. + dph + 2009-12-09T07:21:06Z + biological_process + GO:0003382 + epithelial cell morphogenesis + + + + The change in form that occurs when an epithelial cell progresses from its initial formation to its mature state. + GOC:ascb_2009 + GOC:dph + GOC:tb + - + - + - + - - + + - - - - - - - - - negative regulation of cellular process + Any process that mediates the transfer of information from one cell to another and contributes to the progression of an amphid sensory organ over time, from its formation to the mature state. + dph + 2009-12-09T08:55:37Z + cell-cell signalling involved in amphid sensory organ development + biological_process + GO:0003385 + cell-cell signaling involved in amphid sensory organ development + + + + Any process that mediates the transfer of information from one cell to another and contributes to the progression of an amphid sensory organ over time, from its formation to the mature state. + GOC:ascb_2009 + GOC:dph + GOC:tb + + + + + cell-cell signalling involved in amphid sensory organ development + GOC:mah + - + - - - - - - - - - hematopoietic or lymphoid organ development + + + + + + + + + + + + + + The progression of the amphid sensory organ over time, from its formation to the mature structure. Amphid sensory organs are the sensory organs of nematodes. + dph + 2009-12-09T09:09:20Z + biological_process + GO:0003386 + amphid sensory organ development + + + + The progression of the amphid sensory organ over time, from its formation to the mature structure. Amphid sensory organs are the sensory organs of nematodes. + GOC:ascb_2009 + GOC:dph + GOC:tb + - + - + - + - - + + - - - - - - - - regulation of post-embryonic development + The process in which a relatively unspecialized cell acquires specialized features of a neuron that contributes to the progression of the amphid sensory gland. + dph + 2009-12-09T09:15:00Z + biological_process + GO:0003387 + neuron differentiation involved in amphid sensory organ development + + + + The process in which a relatively unspecialized cell acquires specialized features of a neuron that contributes to the progression of the amphid sensory gland. + GOC:ascb_2009 + GOC:dph + GOC:tb + - + - + - + - - + + - - - - - + + - negative regulation of post-embryonic development + The process whose specific outcome is the progression of a neuron over time, that contributes to the development of the amphid sensory organ. + dph + 2009-12-09T09:18:06Z + biological_process + GO:0003388 + neuron development involved in amphid sensory organ development + + + + The process whose specific outcome is the progression of a neuron over time, that contributes to the development of the amphid sensory organ. + GOC:ascb_2009 + GOC:dph + GOC:tb + - + - + - + - - + + - - - - - - - - - - positive regulation of post-embryonic development + The process in which a relatively unspecialized cell acquires the specialized features of a glial cell of the amphid sensory organ. + dph + 2009-12-09T09:55:27Z + biological_process + GO:0003398 + glial cell differentiation involved in amphid sensory organ development + + + + The process in which a relatively unspecialized cell acquires the specialized features of a glial cell of the amphid sensory organ. + GOC:ascb_2009 + GOC:dph + GOC:tb + - + - + - + - - + + - + + - - + + - regulation of response to stimulus + + + + + + + The developmental process pertaining to the initial formation of the optic vesicle from the lateral wall of the forebrain. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup. + dph + 2009-12-21T01:42:37Z + biological_process + GO:0003403 + optic vesicle formation + + + + The developmental process pertaining to the initial formation of the optic vesicle from the lateral wall of the forebrain. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup. + GOC:ascb_2009 + GOC:dph + GOC:tb + - + - + - + - - + + - - + - - + + - positive regulation of response to stimulus + The developmental process pertaining to the formation and shaping of the optic vesicle. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup. + dph + 2009-12-21T01:54:34Z + biological_process + GO:0003404 + optic vesicle morphogenesis + + + + The developmental process pertaining to the formation and shaping of the optic vesicle. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup. + GOC:ascb_2009 + GOC:dph + GOC:tb + - + - + - + - - + + - - + - - + + - negative regulation of response to stimulus + The progression of the retinal pigment epithelium over time, from its initial formation to the mature structure. The retinal pigment epithelium is the melanin-containing layer of cells between the retina and the choroid that absorbs scattered and reflected light and removes waste products produced by the photoreceptor cells. + dph + 2009-12-21T02:04:27Z + biological_process + RPE development + GO:0003406 + retinal pigment epithelium development + + + + The progression of the retinal pigment epithelium over time, from its initial formation to the mature structure. The retinal pigment epithelium is the melanin-containing layer of cells between the retina and the choroid that absorbs scattered and reflected light and removes waste products produced by the photoreceptor cells. + GOC:ascb_2009 + GOC:dph + GOC:tb + + + + + RPE development + GOC:ascb_2009 + GOC:dph + GOC:tb + - + - - - + + + + + + + + + + + + + + - + - developmental cell growth + The progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells. + dph + 2009-12-21T02:15:14Z + biological_process + GO:0003407 + neural retina development + + + + The progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells. + GOC:ascb_2009 + GOC:dph + GOC:tb + - + - - - - developmental growth + + + + + + + + + + + + + Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another and contributes to the physical shaping or formation of the camera-type eye. + dph + 2009-12-21T03:04:27Z + biological_process + GO:0003411 + cell motility involved in camera-type eye morphogenesis + + + + Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another and contributes to the physical shaping or formation of the camera-type eye. + GOC:ascb_2009 + GOC:dph + GOC:tb + - + - - + + + + + + + + + + + + + - + - embryonic morphogenesis + The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage. + dph + 2009-12-22T08:39:58Z + biological_process + GO:0003413 + chondrocyte differentiation involved in endochondral bone morphogenesis + + + + The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage. + GOC:ascb_2009 + GOC:dph + GOC:tb + - + - - - + + + + + + + + + + + + - + - reproductive structure development + The process in which the structures of a chondrocyte that will contribute to bone development are generated and organized. + dph + 2009-12-22T08:42:55Z + biological_process + GO:0003414 + chondrocyte morphogenesis involved in endochondral bone morphogenesis + + + + The process in which the structures of a chondrocyte that will contribute to bone development are generated and organized. + GOC:ascb_2009 + GOC:dph + GOC:tb + - + - - + + - + - multicellular organismal reproductive process + The growth of a chondrocyte, where growth contributes to the progression of the chondrocyte over time. + dph + 2009-12-22T08:48:44Z + biological_process + GO:0003415 + chondrocyte hypertrophy + + + + The growth of a chondrocyte, where growth contributes to the progression of the chondrocyte over time. + GOC:ascb_2009 + GOC:dph + GOC:tb + - + - + - + - - + + - - - - - - - - - regulation of developmental growth + The increase in size or mass of an endochondral bone that contributes to the shaping of the bone. + dph + 2009-12-22T08:52:55Z + biological_process + GO:0003416 + endochondral bone growth + + + + The increase in size or mass of an endochondral bone that contributes to the shaping of the bone. + GOC:ascb_2009 + GOC:dph + GOC:tb + - + - + - + - - + + - - - + - - + + - positive regulation of developmental growth + The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones as they elongate or grow. + dph + 2009-12-22T08:57:42Z + biological_process + GO:0003417 + growth plate cartilage development + + + + The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones as they elongate or grow. + GOC:ascb_2009 + GOC:dph + GOC:tb + - + - + - + - - + + - - - - - - - - - - negative regulation of developmental growth - - - - - - - - + - + - anatomical structure formation involved in morphogenesis - - - - - - - - - generation of neurons + The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the growth of a bone. A chondrocyte is a polymorphic cell that forms cartilage. + dph + 2009-12-22T09:00:56Z + biological_process + GO:0003418 + growth plate cartilage chondrocyte differentiation + + + + The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the growth of a bone. A chondrocyte is a polymorphic cell that forms cartilage. + GOC:ascb_2009 + GOC:dph + GOC:tb + - + - - + + + + + + + + + + + + + - + - skeletal system morphogenesis + The process in which the anatomical structures of growth plate cartilage are generated and organized. + dph + 2009-12-22T09:21:30Z + biological_process + GO:0003422 + growth plate cartilage morphogenesis + + + + The process in which the anatomical structures of growth plate cartilage are generated and organized. + GOC:ascb_2009 + GOC:dph + GOC:tb + - + - - + + + + + + + + + + + + + - + - tissue morphogenesis + The process in which the structures of a chondrocyte in the growth plate cartilage are generated and organized. + dph + 2009-12-22T12:22:24Z + biological_process + GO:0003429 + growth plate cartilage chondrocyte morphogenesis + + + + The process in which the structures of a chondrocyte in the growth plate cartilage are generated and organized. + GOC:ascb_2009 + GOC:dph + GOC:tb + - + - - + + + + + + + + + + + + + + - + - system development - - - - - - - - - gland development + The growth of a growth plate cartilage chondrocyte, where growth contributes to the progression of the chondrocyte over time from one condition to another. + dph + 2009-12-22T12:29:19Z + growth plate cartilage chondrocyte hypertrophy + biological_process + GO:0003430 + growth plate cartilage chondrocyte growth + + + + The growth of a growth plate cartilage chondrocyte, where growth contributes to the progression of the chondrocyte over time from one condition to another. + GOC:ascb_2009 + GOC:dph + GOC:tb + + + + + growth plate cartilage chondrocyte hypertrophy + GOC:ascb_2009 + GOC:dph + GOC:tb + - + - - - + + + + + + + + + + + + + - + - branching morphogenesis of an epithelial tube - - - - - - - - - pigment granule - - - - - - - - - anatomical structure development + The progression of a growth plate cartilage chondrocyte over time from after its fate commitment to the mature cell. + dph + 2009-12-22T12:32:49Z + biological_process + GO:0003431 + growth plate cartilage chondrocyte development + + + + The progression of a growth plate cartilage chondrocyte over time from after its fate commitment to the mature cell. + GOC:ascb_2009 + GOC:dph + GOC:tb + - + - - - - cellular developmental process + + + + + + + + + + + + + + The growth of a growth plate cartilage chondrocyte, where growth contributes to the shaping of the chondrocyte over time. + dph + 2009-12-22T12:37:48Z + biological_process + GO:0003432 + cell growth involved in growth plate cartilage chondrocyte morphogenesis + + + + The growth of a growth plate cartilage chondrocyte, where growth contributes to the shaping of the chondrocyte over time. + GOC:ascb_2009 + GOC:dph + GOC:tb + - + - - - + + + + + + + + + + + + + - + - cell motility + The progression of a chondrocyte over time from after its commitment to its mature state where the chondrocyte will contribute to the shaping of an endochondral bone. + dph + 2009-12-22T12:42:44Z + biological_process + GO:0003433 + chondrocyte development involved in endochondral bone morphogenesis + + + + The progression of a chondrocyte over time from after its commitment to its mature state where the chondrocyte will contribute to the shaping of an endochondral bone. + GOC:ascb_2009 + GOC:dph + GOC:tb + - + - - - - multicellular organismal homeostasis + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix and contributes to the shaping of the growth plate cartilage of an endochondral bone. + dph + 2009-12-22T01:28:15Z + biological_process + GO:0003436 + regulation of cell adhesion involved in growth plate cartilage morphogenesis + + + + Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix and contributes to the shaping of the growth plate cartilage of an endochondral bone. + GOC:ascb_2009 + GOC:dph + GOC:tb + - + - - - chemical homeostasis + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of cell communication that contributes to the shaping of the growth plate cartilage. + dph + 2009-12-22T01:34:24Z + biological_process + GO:0003437 + regulation of cell communication involved in growth plate cartilage morphogenesis + + + + Any process that modulates the frequency, rate or extent of cell communication that contributes to the shaping of the growth plate cartilage. + GOC:ascb_2009 + GOC:dph + GOC:tb + - + - - - - catecholamine secretion + + + + + A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. These actions are described from two distinct but related perspectives: (1) biochemical activity, and (2) role as a component in a larger system/process. + GO:0005554 + molecular function + molecular_function + GO:0003674 + + + + + + + Note that, in addition to forming the root of the molecular function ontology, this term is recommended for use for the annotation of gene products whose molecular function is unknown. When this term is used for annotation, it indicates that no information was available about the molecular function of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. Despite its name, this is not a type of 'function' in the sense typically defined by upper ontologies such as Basic Formal Ontology (BFO). It is instead a BFO:process carried out by a single gene product or complex. + molecular_function + + + + A molecular process that can be carried out by the action of a single macromolecular machine, usually via direct physical interactions with other molecular entities. Function in this sense denotes an action, or activity, that a gene product (or a complex) performs. These actions are described from two distinct but related perspectives: (1) biochemical activity, and (2) role as a component in a larger system/process. + GOC:pdt + - + - + - + - - + + - - + - - + + - regulation of catecholamine secretion + Combining with a steroid hormone and transmitting the signal within the cell to initiate a change in cell activity or function. + https://github.com/geneontology/go-ontology/issues/16717 + steroid hormone receptor activity + molecular_function + GO:0003707 + nuclear steroid receptor activity + + + + Combining with a steroid hormone and transmitting the signal within the cell to initiate a change in cell activity or function. + GOC:signaling + PMID:14708019 + - + - - - - - + + + Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. + Wikipedia:Enzyme + enzyme activity + molecular_function + GO:0003824 + + + + + + + + catalytic activity + + + + + Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic. + GOC:vw + ISBN:0198506732 + + + + + enzyme activity + GOC:dph + GOC:tb + + + + + + + + + + + Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP. + GO:0050222 + MetaCyc:PROTEIN-KINASE-RXN + Reactome:R-HSA-156832 + Reactome:R-HSA-937034 + Reactome:R-HSA-9604606 + Reactome:R-HSA-9673284 + Reactome:R-HSA-975139 + protamine kinase activity + molecular_function + GO:0004672 + + Note that triphosphate is used as a phosphate donor by at least one kinase. + protein kinase activity + + + + + Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP. + MetaCyc:PROTEIN-KINASE-RXN + + + + + Reactome:R-HSA-156832 + INF-gamma induced phosphorylation of L13a + + + + + Reactome:R-HSA-937034 + IRAK1 phosphorylates Pellino + + + + + Reactome:R-HSA-9604606 + Unknown kinase phosphorylates NICD4 + + + + + Reactome:R-HSA-9673284 + GTP-bound RAC1 contributes to MAPK8 activation + + + + + Reactome:R-HSA-975139 + IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation + + + + + + + + + + + + + + + Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate. + GO:0004718 + EC:2.7.10.2 + RHEA:10596 + Reactome:R-HSA-112333 + Reactome:R-HSA-114600 + Reactome:R-HSA-1168394 + Reactome:R-HSA-1169421 + Reactome:R-HSA-1225952 + Reactome:R-HSA-1225960 + Reactome:R-HSA-1247844 + Reactome:R-HSA-1248655 + Reactome:R-HSA-1248694 + Reactome:R-HSA-1250195 + Reactome:R-HSA-1250315 + Reactome:R-HSA-1250348 + Reactome:R-HSA-1251922 + Reactome:R-HSA-1295540 + Reactome:R-HSA-1295609 + Reactome:R-HSA-1307963 + Reactome:R-HSA-1433418 + Reactome:R-HSA-1433454 + Reactome:R-HSA-1433488 + Reactome:R-HSA-1433506 + Reactome:R-HSA-1433542 + Reactome:R-HSA-1470009 + Reactome:R-HSA-1472121 + Reactome:R-HSA-1524186 + Reactome:R-HSA-1671691 + Reactome:R-HSA-170070 + Reactome:R-HSA-170156 + Reactome:R-HSA-170991 + Reactome:R-HSA-171011 + Reactome:R-HSA-174164 + Reactome:R-HSA-177930 + Reactome:R-HSA-177934 + Reactome:R-HSA-177937 + Reactome:R-HSA-182969 + Reactome:R-HSA-183058 + Reactome:R-HSA-1839065 + Reactome:R-HSA-1839067 + Reactome:R-HSA-1839098 + Reactome:R-HSA-1839110 + Reactome:R-HSA-1839112 + Reactome:R-HSA-186786 + Reactome:R-HSA-1888198 + Reactome:R-HSA-190326 + Reactome:R-HSA-190385 + Reactome:R-HSA-190388 + Reactome:R-HSA-190408 + Reactome:R-HSA-190413 + Reactome:R-HSA-190427 + Reactome:R-HSA-190429 + Reactome:R-HSA-191062 + Reactome:R-HSA-191636 + Reactome:R-HSA-1963581 + Reactome:R-HSA-1963582 + Reactome:R-HSA-1963586 + Reactome:R-HSA-1982066 + Reactome:R-HSA-2012073 + Reactome:R-HSA-2012082 + Reactome:R-HSA-2012087 + Reactome:R-HSA-202165 + Reactome:R-HSA-202168 + Reactome:R-HSA-202174 + Reactome:R-HSA-202216 + Reactome:R-HSA-202233 + Reactome:R-HSA-202245 + Reactome:R-HSA-202248 + Reactome:R-HSA-202291 + Reactome:R-HSA-202307 + Reactome:R-HSA-2023455 + Reactome:R-HSA-2023460 + Reactome:R-HSA-2029268 + Reactome:R-HSA-2029449 + Reactome:R-HSA-2029453 + Reactome:R-HSA-2029459 + Reactome:R-HSA-2029984 + Reactome:R-HSA-2029989 + Reactome:R-HSA-2033485 + Reactome:R-HSA-2033486 + Reactome:R-HSA-2033488 + Reactome:R-HSA-2033490 + Reactome:R-HSA-2038387 + Reactome:R-HSA-2038944 + Reactome:R-HSA-205289 + Reactome:R-HSA-210291 + Reactome:R-HSA-210872 + Reactome:R-HSA-212710 + Reactome:R-HSA-2130194 + Reactome:R-HSA-2197698 + Reactome:R-HSA-2201322 + Reactome:R-HSA-2395412 + Reactome:R-HSA-2395439 + Reactome:R-HSA-2395801 + Reactome:R-HSA-2396594 + Reactome:R-HSA-2404193 + Reactome:R-HSA-2404199 + Reactome:R-HSA-2424484 + Reactome:R-HSA-2424486 + Reactome:R-HSA-2424487 + Reactome:R-HSA-2428926 + Reactome:R-HSA-2454208 + Reactome:R-HSA-2454239 + Reactome:R-HSA-2586553 + Reactome:R-HSA-2586555 + Reactome:R-HSA-2671742 + Reactome:R-HSA-2671829 + Reactome:R-HSA-2671850 + Reactome:R-HSA-2730833 + Reactome:R-HSA-2730843 + Reactome:R-HSA-2730851 + Reactome:R-HSA-2730858 + Reactome:R-HSA-2730860 + Reactome:R-HSA-2730862 + Reactome:R-HSA-2730882 + Reactome:R-HSA-2730884 + Reactome:R-HSA-2730886 + Reactome:R-HSA-2730888 + Reactome:R-HSA-3215391 + Reactome:R-HSA-354073 + Reactome:R-HSA-354124 + Reactome:R-HSA-372693 + Reactome:R-HSA-373747 + Reactome:R-HSA-373750 + Reactome:R-HSA-374701 + Reactome:R-HSA-377640 + Reactome:R-HSA-380780 + Reactome:R-HSA-388831 + Reactome:R-HSA-388833 + Reactome:R-HSA-389083 + Reactome:R-HSA-389086 + Reactome:R-HSA-389354 + Reactome:R-HSA-389762 + Reactome:R-HSA-391156 + Reactome:R-HSA-391865 + Reactome:R-HSA-391866 + Reactome:R-HSA-391871 + Reactome:R-HSA-3928578 + Reactome:R-HSA-3928580 + Reactome:R-HSA-3928583 + Reactome:R-HSA-3928594 + Reactome:R-HSA-3928604 + Reactome:R-HSA-3928610 + Reactome:R-HSA-3928627 + Reactome:R-HSA-3928648 + Reactome:R-HSA-399934 + Reactome:R-HSA-399946 + Reactome:R-HSA-399947 + Reactome:R-HSA-4093332 + Reactome:R-HSA-418163 + Reactome:R-HSA-418859 + Reactome:R-HSA-418872 + Reactome:R-HSA-419646 + Reactome:R-HSA-428888 + Reactome:R-HSA-429441 + Reactome:R-HSA-429449 + Reactome:R-HSA-432129 + Reactome:R-HSA-434836 + Reactome:R-HSA-4420117 + Reactome:R-HSA-4420121 + Reactome:R-HSA-4420128 + Reactome:R-HSA-4420206 + Reactome:R-HSA-443817 + Reactome:R-HSA-445076 + Reactome:R-HSA-445084 + Reactome:R-HSA-445085 + Reactome:R-HSA-445091 + Reactome:R-HSA-451942 + Reactome:R-HSA-452097 + Reactome:R-HSA-452100 + Reactome:R-HSA-452122 + Reactome:R-HSA-508282 + Reactome:R-HSA-5218640 + Reactome:R-HSA-5218642 + Reactome:R-HSA-5218806 + Reactome:R-HSA-5218809 + Reactome:R-HSA-5218812 + Reactome:R-HSA-5218820 + Reactome:R-HSA-5218828 + Reactome:R-HSA-5218830 + Reactome:R-HSA-5218851 + Reactome:R-HSA-5357429 + Reactome:R-HSA-5607745 + Reactome:R-HSA-5607750 + Reactome:R-HSA-5621355 + Reactome:R-HSA-5621363 + Reactome:R-HSA-5621370 + Reactome:R-HSA-5624486 + Reactome:R-HSA-5637795 + Reactome:R-HSA-5637796 + Reactome:R-HSA-5654147 + Reactome:R-HSA-5654149 + Reactome:R-HSA-5654151 + Reactome:R-HSA-5654222 + Reactome:R-HSA-5654397 + Reactome:R-HSA-5654407 + Reactome:R-HSA-5654408 + Reactome:R-HSA-5654418 + Reactome:R-HSA-5654428 + Reactome:R-HSA-5654545 + Reactome:R-HSA-5654575 + Reactome:R-HSA-5654578 + Reactome:R-HSA-5654582 + Reactome:R-HSA-5654587 + Reactome:R-HSA-5654605 + Reactome:R-HSA-5654607 + Reactome:R-HSA-5654628 + Reactome:R-HSA-5654631 + Reactome:R-HSA-5654634 + Reactome:R-HSA-5654653 + Reactome:R-HSA-5654655 + Reactome:R-HSA-5655243 + Reactome:R-HSA-5655268 + Reactome:R-HSA-5655270 + Reactome:R-HSA-5655278 + Reactome:R-HSA-5655284 + Reactome:R-HSA-5655301 + Reactome:R-HSA-5655341 + Reactome:R-HSA-5683930 + Reactome:R-HSA-5686587 + Reactome:R-HSA-5690702 + Reactome:R-HSA-6784006 + Reactome:R-HSA-6784319 + Reactome:R-HSA-6790087 + Reactome:R-HSA-6806974 + Reactome:R-HSA-68954 + Reactome:R-HSA-69195 + Reactome:R-HSA-873918 + Reactome:R-HSA-873919 + Reactome:R-HSA-873922 + Reactome:R-HSA-873924 + Reactome:R-HSA-879907 + Reactome:R-HSA-879909 + Reactome:R-HSA-879925 + Reactome:R-HSA-8847977 + Reactome:R-HSA-8848005 + Reactome:R-HSA-8848077 + Reactome:R-HSA-8848124 + Reactome:R-HSA-8848436 + Reactome:R-HSA-8848606 + Reactome:R-HSA-8848726 + Reactome:R-HSA-8848758 + Reactome:R-HSA-8848776 + Reactome:R-HSA-8848818 + Reactome:R-HSA-8848873 + Reactome:R-HSA-8848975 + Reactome:R-HSA-8849032 + Reactome:R-HSA-8849042 + Reactome:R-HSA-8849068 + Reactome:R-HSA-8849102 + Reactome:R-HSA-8849463 + Reactome:R-HSA-8851890 + Reactome:R-HSA-8851933 + Reactome:R-HSA-8853309 + Reactome:R-HSA-8853313 + Reactome:R-HSA-8853315 + Reactome:R-HSA-8853325 + Reactome:R-HSA-8855237 + Reactome:R-HSA-8857555 + Reactome:R-HSA-8857577 + Reactome:R-HSA-8857583 + Reactome:R-HSA-8857925 + Reactome:R-HSA-8867041 + Reactome:R-HSA-8874078 + Reactome:R-HSA-8874080 + Reactome:R-HSA-8874082 + Reactome:R-HSA-8875451 + Reactome:R-HSA-8875817 + Reactome:R-HSA-8876230 + Reactome:R-HSA-8876246 + Reactome:R-HSA-8876948 + Reactome:R-HSA-8937728 + Reactome:R-HSA-8937807 + Reactome:R-HSA-8937844 + Reactome:R-HSA-8942607 + Reactome:R-HSA-8948143 + Reactome:R-HSA-8956659 + Reactome:R-HSA-8964242 + Reactome:R-HSA-8964252 + Reactome:R-HSA-8983872 + Reactome:R-HSA-9006323 + Reactome:R-HSA-9006332 + Reactome:R-HSA-9011241 + Reactome:R-HSA-9012650 + Reactome:R-HSA-9018572 + Reactome:R-HSA-9021609 + Reactome:R-HSA-9024726 + Reactome:R-HSA-9026464 + Reactome:R-HSA-9026502 + Reactome:R-HSA-9026510 + Reactome:R-HSA-9026579 + Reactome:R-HSA-9026890 + Reactome:R-HSA-9027272 + Reactome:R-HSA-9027273 + Reactome:R-HSA-9027425 + Reactome:R-HSA-9028728 + Reactome:R-HSA-9029151 + Reactome:R-HSA-9029155 + Reactome:R-HSA-9032426 + Reactome:R-HSA-9032532 + Reactome:R-HSA-9032601 + Reactome:R-HSA-9032854 + Reactome:R-HSA-9033284 + Reactome:R-HSA-9034714 + Reactome:R-HSA-9034814 + Reactome:R-HSA-9034875 + Reactome:R-HSA-9037040 + Reactome:R-HSA-909718 + Reactome:R-HSA-909726 + Reactome:R-HSA-909729 + Reactome:R-HSA-909730 + Reactome:R-HSA-909732 + Reactome:R-HSA-912629 + Reactome:R-HSA-9603420 + Reactome:R-HSA-9604767 + Reactome:R-HSA-9606159 + Reactome:R-HSA-9606162 + Reactome:R-HSA-9606163 + Reactome:R-HSA-9612085 + Reactome:R-HSA-9612996 + Reactome:R-HSA-9613023 + Reactome:R-HSA-9625487 + Reactome:R-HSA-9634390 + Reactome:R-HSA-9664261 + Reactome:R-HSA-9664275 + Reactome:R-HSA-9664278 + Reactome:R-HSA-9664588 + Reactome:R-HSA-9664976 + Reactome:R-HSA-9665032 + Reactome:R-HSA-9665389 + Reactome:R-HSA-9665411 + Reactome:R-HSA-9665704 + Reactome:R-HSA-9665705 + Reactome:R-HSA-9665709 + Reactome:R-HSA-9666425 + Reactome:R-HSA-9669890 + Reactome:R-HSA-9669911 + Reactome:R-HSA-9670412 + Reactome:R-HSA-9670418 + Reactome:R-HSA-9672173 + Reactome:R-HSA-9672175 + Reactome:R-HSA-9673756 + Reactome:R-HSA-9673761 + Reactome:R-HSA-9680248 + Reactome:R-HSA-9695834 + Reactome:R-HSA-9698003 + Reactome:R-HSA-9698005 + Reactome:R-HSA-9699578 + Reactome:R-HSA-9703437 + Reactome:R-HSA-9703438 + Reactome:R-HSA-9706344 + Reactome:R-HSA-9706350 + Reactome:R-HSA-982807 + Reactome:R-HSA-983703 + Reactome:R-HSA-983707 + Reactome:R-HSA-983709 + protein-tyrosine kinase activity + molecular_function + GO:0004713 + protein tyrosine kinase activity + + + + + Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate. + RHEA:10596 + + + + + EC:2.7.10.2 + skos:narrowMatch + + + + + RHEA:10596 + skos:exactMatch + + + + + Reactome:R-HSA-112333 + SRC autophosphorylation is positively regulated by InlA-bound CDH1 + + + + + Reactome:R-HSA-114600 + Fyn/Lyn-mediated phosphorylation of FcR1 gamma + + + + + Reactome:R-HSA-1168394 + STAT5 tyrosine phosphorylation + + + + + Reactome:R-HSA-1169421 + Trans-autophosphorylation of activated ligand-responsive EGFR mutant dimers + + + + + Reactome:R-HSA-1225952 + Phosphorylation of SHC1 by ligand-responsive p-6Y-EGFR mutants + + + + + Reactome:R-HSA-1225960 + Phosphorylation of CBL by ligand-responsive p-6Y-EGFR mutants + + + + + Reactome:R-HSA-1247844 + Phosphorylation of PLCG1 by ligand-responsive p-6Y-EGFR mutants + + + + + Reactome:R-HSA-1248655 + Trans-autophosphorylation of EGFRvIII mutant dimers + + + + + Reactome:R-HSA-1248694 + Trans-autophosphorylation of ERBB2 homodimer + + + + + Reactome:R-HSA-1250195 + SHC1 phosphorylation by ERBB2 heterodimers + + + + + Reactome:R-HSA-1250315 + Trans-autophosphorylation of ERBB4 homodimers + + + + + Reactome:R-HSA-1250348 + Phosphorylation of SHC1 by ERBB4 homodimers + + + + + Reactome:R-HSA-1251922 + PLCG1 phosphorylation by p-EGFR:p-ERBB2 + + + + + Reactome:R-HSA-1295540 + IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5 + + + + + Reactome:R-HSA-1295609 + SRC phosphorylates SPRY2 on Y55 and Y227 + + + + + Reactome:R-HSA-1307963 + Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 + + + + + Reactome:R-HSA-1433418 + Phosphorylation of JAK2 + + + + + Reactome:R-HSA-1433454 + Phosphorylation of GAB2 by SFKs + + + + + Reactome:R-HSA-1433488 + Phosphorylation of SHP2 by SFKs + + + + + Reactome:R-HSA-1433506 + Phosphorylation of APS + + + + + Reactome:R-HSA-1433542 + Phosphorylation and activation of VAV1 + + + + + Reactome:R-HSA-1470009 + Phosphorylation of STATs + + + + + Reactome:R-HSA-1472121 + Phosphorylation of p-KIT on Y900 by Src kinases + + + + + Reactome:R-HSA-1524186 + Phosphorylation of PLCgamma by PDGFR + + + + + Reactome:R-HSA-1671691 + PRLR-bound STAT5 is phosphorylated + + + + + Reactome:R-HSA-170070 + Wee1-mediated phosphorylation of Cyclin B1:phospho-Cdc2 complexes + + + + + Reactome:R-HSA-170156 + Wee1-mediated phosphorylation of Cyclin A:phospho-Cdc2 complexes + + + + + Reactome:R-HSA-170991 + SRC-1 autophosphorylates + + + + + Reactome:R-HSA-171011 + Binding and activation of MAP Kinase + + + + + Reactome:R-HSA-174164 + Phosphorylation of Cyclin A:Cdk2 at Tyr 15 + + + + + Reactome:R-HSA-177930 + GAB1 phosphorylation by EGFR kinase + + + + + Reactome:R-HSA-177934 + EGFR autophosphorylation + + + + + Reactome:R-HSA-177937 + Phosphorylation of EGFR by SRC kinase + + + + + Reactome:R-HSA-182969 + Phosphorylation of CBL (EGFR:CBL) + + + + + Reactome:R-HSA-183058 + Phosphorylation of CBL (EGFR:GRB2:CBL) + + + + + Reactome:R-HSA-1839065 + Phosphorylation of cytosolic FGFR1 fusion dimers + + + + + Reactome:R-HSA-1839067 + Phosphorylation of BCR moiety of BCR-FGFR1 + + + + + Reactome:R-HSA-1839098 + Activated FGFR1 mutants and fusions phosphorylate PLCG1 + + + + + Reactome:R-HSA-1839110 + p-BCR-p-FGFR1 phosphorylates GAB2 + + + + + Reactome:R-HSA-1839112 + Phosphorylation of STAT5 by cytosolic FGFR1 fusions + + + + + Reactome:R-HSA-186786 + Autophosphorylation of PDGF beta receptors + + + + + Reactome:R-HSA-1888198 + FGFR1OP-FGFR1 phosphorylates STAT1 and STAT3 + + + + + Reactome:R-HSA-190326 + Autocatalytic phosphorylation of FGFR4 + + + + + Reactome:R-HSA-190385 + Autocatalytic phosphorylation of FGFR3b + + + + + Reactome:R-HSA-190388 + Autocatalytic phosphorylation of FGFR3c + + + + + Reactome:R-HSA-190408 + Autocatalytic phosphorylation of FGFR2b + + + + + Reactome:R-HSA-190413 + Autocatalytic phosphorylation of FGFR2c + + + + + Reactome:R-HSA-190427 + Autocatalytic phosphorylation of FGFR1b + + + + + Reactome:R-HSA-190429 + Autocatalytic phosphorylation of FGFR1c + + + + + Reactome:R-HSA-191062 + Autocatalytic phosphorylation of Klotho-bound FGFR1c + + + + + Reactome:R-HSA-191636 + Phosphorylation of Cx43 by c-src + + + + + Reactome:R-HSA-1963581 + Trans-autophosphorylation of p-Y877-ERBB2 heterodimers + + + + + Reactome:R-HSA-1963582 + Trans-autophosphorylation of ERBB2 heterodimers + + + + + Reactome:R-HSA-1963586 + SRC family kinases phosphorylate ERBB2 + + + + + Reactome:R-HSA-1982066 + Ligand-independent phosphorylation of overexpressed FGFR1 + + + + + Reactome:R-HSA-2012073 + Autocatalytic phosphorylation of FGFR3c P250R mutant + + + + + Reactome:R-HSA-2012082 + Autocatalytic phosphorylation of FGFR3 cysteine mutants + + + + + Reactome:R-HSA-2012087 + Autocatalytic phosphorylation of FGFR4 Y367C mutant + + + + + Reactome:R-HSA-202165 + Phosphorylation of ITAM motifs in CD3 complexes + + + + + Reactome:R-HSA-202168 + Phosphorylation of ZAP-70 by Lck + + + + + Reactome:R-HSA-202174 + Activation of ZAP-70 + + + + + Reactome:R-HSA-202216 + Phosphorylation of SLP-76 + + + + + Reactome:R-HSA-202233 + Inactivation of Lck by Csk + + + + + Reactome:R-HSA-202245 + Phosphorylation of TBSMs in LAT + + + + + Reactome:R-HSA-202248 + Phosphorylation of PLC-gamma1 + + + + + Reactome:R-HSA-202291 + Activation of Lck + + + + + Reactome:R-HSA-202307 + Change of PKC theta conformation + + + + + Reactome:R-HSA-2023455 + Autocatalytic phosphorylation of FGFR1c P252X mutant dimers + + + + + Reactome:R-HSA-2023460 + Autocatalytic phosphorylation of FGFR1 mutants with enhanced kinase activity + + + + + Reactome:R-HSA-2029268 + Phosphorylation and activation of PLCG + + + + + Reactome:R-HSA-2029449 + Phosphorylation of SYK by Src kinases + + + + + Reactome:R-HSA-2029453 + Phosphorylation of VAV + + + + + Reactome:R-HSA-2029459 + Sequestering and phosphorylation Fc gamma receptors in the lipid rafts + + + + + Reactome:R-HSA-2029984 + Autocatalytic phosphorylation of FGFR2 ligand-independent mutants + + + + + Reactome:R-HSA-2029989 + Autocatalytic phosphorylation of overexpressed FGFR2 variants + + + + + Reactome:R-HSA-2033485 + Autocatalytic phosphorylation of FGFR3 point mutants with enhanced kinase activity + + + + + Reactome:R-HSA-2033486 + Autocatalytic phosphorylation of FGFR2c mutants with enhanced ligand binding + + + + + Reactome:R-HSA-2033488 + Autocatalytic phosphorylation of FGFR2b mutants with enhanced ligand binding + + + + + Reactome:R-HSA-2033490 + Autocatalytic phosphorylation of FGFR2 point mutants with enhanced kinase activity + + + + + Reactome:R-HSA-2038387 + Autocatalytic phosphorylation of FGFR3 t(4;14) translocation mutants + + + + + Reactome:R-HSA-2038944 + Autocatalytic phosphorylation of FGFR4 mutants with enhanced kinase activity + + + + + Reactome:R-HSA-205289 + Autophosphorylation of KIT + + + + + Reactome:R-HSA-210291 + Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src + + + + + Reactome:R-HSA-210872 + Trans-phosphorylation of Tie2 + + + + + Reactome:R-HSA-212710 + EGFR activates PLC-gamma1 by phosphorylation + + + + + Reactome:R-HSA-2130194 + ABL phosphorylates WAVEs + + + + + Reactome:R-HSA-2197698 + Src phosphorylate WASP,N-WASP + + + + + Reactome:R-HSA-2201322 + TIRAP is phosphorylated by BTK + + + + + Reactome:R-HSA-2395412 + Phosphorylation of SYK + + + + + Reactome:R-HSA-2395439 + Phosphorylation of DAP12 + + + + + Reactome:R-HSA-2395801 + Phosphorylation of LAT by p-SYK + + + + + Reactome:R-HSA-2396594 + Phosphorylation of SLP-76 by p-SYK + + + + + Reactome:R-HSA-2404193 + IGF1R phosphorylates SHC1 + + + + + Reactome:R-HSA-2404199 + IGF1,2:IGF1R autophosphorylates + + + + + Reactome:R-HSA-2424484 + Phosphorylation of BTK by p-SYK + + + + + Reactome:R-HSA-2424486 + Phosphorylation and activation of VAV2/VAV3 by SYK + + + + + Reactome:R-HSA-2424487 + Phosphorylation of PLC-gamma by p-BTK/p-SYK + + + + + Reactome:R-HSA-2428926 + IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 + + + + + Reactome:R-HSA-2454208 + Phosphorylation of beta and gamma subunits by LYN + + + + + Reactome:R-HSA-2454239 + Phosphorylation of SYK + + + + + Reactome:R-HSA-2586553 + JAK2 Phosphorylates LEPR + + + + + Reactome:R-HSA-2586555 + JAK2 Autophosphorylates in Response to Leptin + + + + + Reactome:R-HSA-2671742 + JAK2 Phosphorylates SHP2 (PTPN11) in Response to Leptin + + + + + Reactome:R-HSA-2671829 + JAK2 Phosphorylates STAT5 in Response to Leptin + + + + + Reactome:R-HSA-2671850 + JAK2 Phosphoryates STAT3 in Response to Leptin + + + + + Reactome:R-HSA-2730833 + Phosphorylation of TEC kinases by p-SYK + + + + + Reactome:R-HSA-2730843 + Phosphorylation of LAT by p-SYK + + + + + Reactome:R-HSA-2730851 + Phosphorylation of SLP-76 by p-SYK + + + + + Reactome:R-HSA-2730858 + Autophosphorylation of BTK/ITK + + + + + Reactome:R-HSA-2730860 + Phosphorylation of GAB2 by SYK/FYN + + + + + Reactome:R-HSA-2730862 + Autophosphorylation of LYN kinase + + + + + Reactome:R-HSA-2730882 + Phosphorylation of PKC-theta + + + + + Reactome:R-HSA-2730884 + Phosphorylation of NTAL by p-SYK/Lyn + + + + + Reactome:R-HSA-2730886 + Phosphorylation of SHC by SYK kinase + + + + + Reactome:R-HSA-2730888 + Phosphorylation of PLC-gamma + + + + + Reactome:R-HSA-3215391 + PRMT5 is tyrosine phosphorylated by JAK2 V617F + + + + + Reactome:R-HSA-354073 + Autophosphorylation of PTK2 at Y397 + + + + + Reactome:R-HSA-354124 + Phosphorylation of pPTK2 by SRC + + + + + Reactome:R-HSA-372693 + Phosphorylation of BCAR1 by SRC-PTK2 complex + + + + + Reactome:R-HSA-373747 + Phosphorylation of nephrin by FYN + + + + + Reactome:R-HSA-373750 + SEMA4D interacts with Plexin-B1:ErbB2 + + + + + Reactome:R-HSA-374701 + Phosphorylation of DCC by Fyn + + + + + Reactome:R-HSA-377640 + Autophosphorylation of SRC + + + + + Reactome:R-HSA-380780 + Activation of Src + + + + + Reactome:R-HSA-388831 + Phosphorylation of CD28 + + + + + Reactome:R-HSA-388833 + Phosphorylation of CTLA-4 + + + + + Reactome:R-HSA-389083 + Autophosphorylation of PDGF alpha receptors + + + + + Reactome:R-HSA-389086 + Autophosphorylation of PDGF alpha/beta receptors + + + + + Reactome:R-HSA-389354 + Activation of Vav1 + + + + + Reactome:R-HSA-389762 + Phosphorylation of PD-1 + + + + + Reactome:R-HSA-391156 + Phosphorylation of ITIM motif in SIRP alpha + + + + + Reactome:R-HSA-391865 + Recruitment of FAK to NCAM1:Fyn in lipid rafts + + + + + Reactome:R-HSA-391866 + Phosphorylation of FAK by Src kinase + + + + + Reactome:R-HSA-391871 + Autophosphorylation of NCAM1 bound Fyn + + + + + Reactome:R-HSA-3928578 + EPH receptors autophosphorylate + + + + + Reactome:R-HSA-3928580 + SFKs phosphorylate EFNBs + + + + + Reactome:R-HSA-3928583 + FYN phosphorylates NMDAR2B + + + + + Reactome:R-HSA-3928594 + SFKs phosphorylate GIT1 + + + + + Reactome:R-HSA-3928604 + SFKs phosphorylate VAV2,3 + + + + + Reactome:R-HSA-3928610 + PTK2 autophosphorylates at Y397 + + + + + Reactome:R-HSA-3928627 + EPHB phosphorylates TIAM1 + + + + + Reactome:R-HSA-3928648 + SFKs phosphorylate NGEF + + + + + Reactome:R-HSA-399934 + Phosphorylation of Plexin-A + + + + + Reactome:R-HSA-399946 + Recruitment and activation of Cdk5 + + + + + Reactome:R-HSA-399947 + Tyrosine phosphorylation of CRMPs by Fes + + + + + Reactome:R-HSA-4093332 + p-EPHB phosphorylates SDC2 + + + + + Reactome:R-HSA-418163 + Activated Src activates ERK + + + + + Reactome:R-HSA-418859 + Phosphorylation of Unc5C + + + + + Reactome:R-HSA-418872 + Phosphorylation of FADK1 + + + + + Reactome:R-HSA-419646 + SEMA4D interacts with Plexin-B1:Met + + + + + Reactome:R-HSA-428888 + Phosphorylation of ROBO1 by ABL kinase + + + + + Reactome:R-HSA-429441 + SYK activation by SRC + + + + + Reactome:R-HSA-429449 + Syk activation leads to SLP-76 activation + + + + + Reactome:R-HSA-432129 + FGR binds and phosphorylates LRP8 + + + + + Reactome:R-HSA-434836 + Syk/Lck phosphorylate LAT + + + + + Reactome:R-HSA-4420117 + VEGFR2 autophosphorylates + + + + + Reactome:R-HSA-4420121 + SFKs phosphorylate PLCG1 + + + + + Reactome:R-HSA-4420128 + SRC-1 phosphorylates SHB + + + + + Reactome:R-HSA-4420206 + Phosphorylation of SRC-1 + + + + + Reactome:R-HSA-443817 + Phosphorylation of L1 by EPHB2 + + + + + Reactome:R-HSA-445076 + Phosphorylation of Y1229 in L1 + + + + + Reactome:R-HSA-445084 + Phosphorylation of L1 by SRC + + + + + Reactome:R-HSA-445085 + Phosphorylation of VAV2 + + + + + Reactome:R-HSA-445091 + Phosphorylation of Neurofascin + + + + + Reactome:R-HSA-451942 + Within the IL-2R complex JAK3 phosphorylates JAK1 + + + + + Reactome:R-HSA-452097 + Recruited STAT5 is phosphorylated + + + + + Reactome:R-HSA-452100 + SHC1 bound to IL2 receptor is phosphorylated + + + + + Reactome:R-HSA-452122 + JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB + + + + + Reactome:R-HSA-508282 + SYK is a substrate for JAK1 + + + + + Reactome:R-HSA-5218640 + SRC-1 phosphorylates p-Y397-PTK2 + + + + + Reactome:R-HSA-5218642 + PTK2 autophosphorylates + + + + + Reactome:R-HSA-5218806 + FYN autophosphorylates + + + + + Reactome:R-HSA-5218809 + PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 + + + + + Reactome:R-HSA-5218812 + FYN phosphorylates PAK2 + + + + + Reactome:R-HSA-5218820 + Src kinases phosphorylate VAV + + + + + Reactome:R-HSA-5218828 + PTK2/SRC-1 phosphorylates BCAR1 + + + + + Reactome:R-HSA-5218830 + SRC-1 phosphorylates PTK2-beta + + + + + Reactome:R-HSA-5218851 + p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 + + + + + Reactome:R-HSA-5357429 + AXL autophosphorylates on Y772 and Y814 + + + + + Reactome:R-HSA-5607745 + 1,3-beta-D-glucan:p-Y15-CLEC7A:SYK phosphorylates PLCG + + + + + Reactome:R-HSA-5607750 + SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan + + + + + Reactome:R-HSA-5621355 + LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG + + + + + Reactome:R-HSA-5621363 + SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 + + + + + Reactome:R-HSA-5621370 + SYK autophosphorylates + + + + + Reactome:R-HSA-5624486 + SFKs phosphorylates RAF1 on Y340,Y341 + + + + + Reactome:R-HSA-5637795 + Phosphorylation of PLC-gamma 1 by p-EGFRvIII mutant + + + + + Reactome:R-HSA-5637796 + Phosphorylation of SHC1 by p-5Y-EGFRvIII + + + + + Reactome:R-HSA-5654147 + Activated FGFR2 phosphorylates PLCG1 + + + + + Reactome:R-HSA-5654149 + Activated FGFR1 phosphorylates PLCG1 + + + + + Reactome:R-HSA-5654151 + Activated FGFR4 phosphorylates PLCG1 + + + + + Reactome:R-HSA-5654222 + Activated FGFR3 phosphorylates PLCG1 + + + + + Reactome:R-HSA-5654397 + Activated FGFR2 phosphorylates FRS2 + + + + + Reactome:R-HSA-5654407 + Activated FGFR2 phosphorylates SHC1 + + + + + Reactome:R-HSA-5654408 + Activated FGFR3 phosphorylates FRS2 + + + + + Reactome:R-HSA-5654418 + Activated FGFR4 phosphorylates FRS2 + + + + + Reactome:R-HSA-5654428 + Activated FGFR4 phosphorylates SHC1 + + + + + Reactome:R-HSA-5654545 + Ligand-independent phosphorylation of overexpressed FGFR1c + + + + + Reactome:R-HSA-5654575 + Activated FGFR1 phosphorylates FRS2 + + + + + Reactome:R-HSA-5654578 + Activated FGFR1 phosphorylates FRS3 + + + + + Reactome:R-HSA-5654582 + Activated FGFR1 phosphorylates SHC1 + + + + + Reactome:R-HSA-5654587 + Activated FGFR1:p-FRS phosphorylates PPTN11 + + + + + Reactome:R-HSA-5654605 + Activated FGFR2 phosphorylates FRS3 + + + + + Reactome:R-HSA-5654607 + Activated FGFR2 phosphorylates PPTN11 + + + + + Reactome:R-HSA-5654628 + Activated FGFR3 phosphorylates FRS3 + + + + + Reactome:R-HSA-5654631 + Activated FGFR3 phosphorylates PPTN11 + + + + + Reactome:R-HSA-5654634 + Activated FGFR3 phosphorylates SHC1 + + + + + Reactome:R-HSA-5654653 + Activated FGFR4 phosphorylates FRS3 + + + + + Reactome:R-HSA-5654655 + Activated FGFR4 phosphorylates PPTN11 + + + + + Reactome:R-HSA-5655243 + Activated FGFR3 mutants phosphorylate PLCG1 + + + + + Reactome:R-HSA-5655268 + Activated FGFR2 mutants phosphorylate FRS2 + + + + + Reactome:R-HSA-5655270 + Activated FGFR3 mutants phosphorylate FRS2 + + + + + Reactome:R-HSA-5655278 + Activated FGFR1 mutants phosphorylate FRS2 + + + + + Reactome:R-HSA-5655284 + Activated FGFR4 mutants phosphorylate FRS2 + + + + + Reactome:R-HSA-5655301 + Activated FGFR2 mutants phosphorylate PLCG1 + + + + + Reactome:R-HSA-5655341 + Activated FGFR4 mutants phosphorylate PLCG1 + + + + + Reactome:R-HSA-5683930 + WICH phosphorylates H2AFX on Y142 + + + + + Reactome:R-HSA-5686587 + ABL1 phosphorylates RAD52 + + + + + Reactome:R-HSA-5690702 + LYN phosphorylates CD22 + + + + + Reactome:R-HSA-6784006 + STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 + + + + + Reactome:R-HSA-6784319 + JAK1,TYK2 phosphorylate JAK1,TYK2 + + + + + Reactome:R-HSA-6790087 + HVEM induses BTLA phosphorylation + + + + + Reactome:R-HSA-6806974 + MET dimers autophosphorylate + + + + + Reactome:R-HSA-68954 + Mcm2-7 is phosphorylated by DDK + + + + + Reactome:R-HSA-69195 + Phosphorylation of Cyclin E:CDK2 complexes by WEE1 + + + + + Reactome:R-HSA-873918 + Transphosphorylation of JAK1 + + + + + Reactome:R-HSA-873919 + Phosphorylation of JAK2 + + + + + Reactome:R-HSA-873922 + Phosphorylation of STAT1 by JAK kinases + + + + + Reactome:R-HSA-873924 + Phosphorylation of IFNGR1 by JAK kinases + + + + + Reactome:R-HSA-879907 + Tyrosine kinases phosphorylate the receptor + + + + + Reactome:R-HSA-879909 + Activation of STAT5a/b by JAK2 + + + + + Reactome:R-HSA-879925 + SHC1 bound to the common beta chain becomes tyrosine phosphorylated + + + + + Reactome:R-HSA-8847977 + FRK phosphorylates PTEN + + + + + Reactome:R-HSA-8848005 + ERBB2 promotes PTK6 autophosphorylation + + + + + Reactome:R-HSA-8848077 + PTK6 phosphorylates STAP2 + + + + + Reactome:R-HSA-8848124 + PTK6 phosphorylates STAT3 + + + + + Reactome:R-HSA-8848436 + PTK6 phosphorylates CDKN1B + + + + + Reactome:R-HSA-8848606 + PTK6 phosphorylates PXN + + + + + Reactome:R-HSA-8848726 + PTK6 phosphorylates BCAR1 + + + + + Reactome:R-HSA-8848758 + PTK6 phosphorylates AKT1 + + + + + Reactome:R-HSA-8848776 + PTK6 phosphorylates DOK1 + + + + + Reactome:R-HSA-8848818 + PTK6 phosphorylates CBL + + + + + Reactome:R-HSA-8848873 + PTK6 phosphorylates ARAP1 + + + + + Reactome:R-HSA-8848975 + PTK6 phosphorylates KHDRBS1 + + + + + Reactome:R-HSA-8849032 + PTK6 phosphorylates KHDRBS2 + + + + + Reactome:R-HSA-8849042 + PTK6 phosphorylates KHDRBS3 + + + + + Reactome:R-HSA-8849068 + PTK6 phosphorylates ARHGAP35 + + + + + Reactome:R-HSA-8849102 + SRMS phosphorylates PTK6 + + + + + Reactome:R-HSA-8849463 + PTK6 phosphorylates SFPQ + + + + + Reactome:R-HSA-8851890 + MET phosphorylates SHC1-2 + + + + + Reactome:R-HSA-8851933 + MET phosphorylates GAB1 + + + + + Reactome:R-HSA-8853309 + Autocatalytic phosphorylation of FGFR3 fusions + + + + + Reactome:R-HSA-8853313 + FGFR2 fusions autophosphorylate + + + + + Reactome:R-HSA-8853315 + Activated FGFR3 fusions phosphorylate FRS2 + + + + + Reactome:R-HSA-8853325 + Plasma membrane FGFR1 fusions autophosphorylate + + + + + Reactome:R-HSA-8855237 + FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1 + + + + + Reactome:R-HSA-8857555 + EGFR phosphorylates GPNMB + + + + + Reactome:R-HSA-8857577 + LINC01139 facilitates PTK6 autophosphorylation + + + + + Reactome:R-HSA-8857583 + LINC01139 promotes phosphorylation of HIF1A by PTK6 + + + + + Reactome:R-HSA-8857925 + Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 + + + + + Reactome:R-HSA-8867041 + EGFR phosphorylates EPS15 + + + + + Reactome:R-HSA-8874078 + PTK2 autophosphorylates + + + + + Reactome:R-HSA-8874080 + SRC phosphorylates PTK2 + + + + + Reactome:R-HSA-8874082 + MET phosphorylates PTK2 + + + + + Reactome:R-HSA-8875451 + MET phosphorylates CBL + + + + + Reactome:R-HSA-8875817 + MET phosphorylates STAT3 + + + + + Reactome:R-HSA-8876230 + InlB:MET dimer trans-autophophorylates + + + + + Reactome:R-HSA-8876246 + InlB-activated MET phosphorylates CBL + + + + + Reactome:R-HSA-8876948 + SRC phosphorylates InlA-bound CDH1 and CTNNB1 + + + + + Reactome:R-HSA-8937728 + SRC phosphorylates RUNX1 + + + + + Reactome:R-HSA-8937807 + SRC phosphorylates RUNX3 + + + + + Reactome:R-HSA-8937844 + SRC,YES1 phosphorylate YAP1 + + + + + Reactome:R-HSA-8942607 + Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes + + + + + Reactome:R-HSA-8948143 + p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 + + + + + Reactome:R-HSA-8956659 + ABL1 phosphorylates YAP1 + + + + + Reactome:R-HSA-8964242 + G protein alpha (i)-SRC complex catalyzes SRC to p-Y416-SRC + + + + + Reactome:R-HSA-8964252 + G alpha (s):GTP:SRC catalyzes SRC to p-Y416-SRC + + + + + Reactome:R-HSA-8983872 + JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 + + + + + Reactome:R-HSA-9006323 + Phospho-JAK2 phosphorylates EPOR + + + + + Reactome:R-HSA-9006332 + JAK2 transphosphorylates and is activated in response to Erythropoietin + + + + + Reactome:R-HSA-9011241 + SRC phosphorylates ROBO3.1 in response to NTN1 + + + + + Reactome:R-HSA-9012650 + JAK2 and LYN phosphorylate STAT5 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 + + + + + Reactome:R-HSA-9018572 + EGFR phosphorylates NOTCH3 + + + + + Reactome:R-HSA-9021609 + ESR-associated SRC autophosphorylates + + + + + Reactome:R-HSA-9024726 + LYN phosphorylates CRKL in EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:CRKL:RAPGEF1 + + + + + Reactome:R-HSA-9026464 + BDNF-bound NTRK2 dimers trans-autophosphorylate + + + + + Reactome:R-HSA-9026502 + NTF3-bound NTRK2 dimers trans-autophosphorylate + + + + + Reactome:R-HSA-9026510 + NTF4-bound NTRK2 dimers trans-autophosphorylate + + + + + Reactome:R-HSA-9026579 + NTRK2 phosphorylates PLCG1 + + + + + Reactome:R-HSA-9026890 + NTRK2 phosphorylates SHC1 + + + + + Reactome:R-HSA-9027272 + EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2 + + + + + Reactome:R-HSA-9027273 + JAK2 phosphorylates GAB1 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:GAB1 + + + + + Reactome:R-HSA-9027425 + LYN phosphorylates PLCG1,2 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:PLCG1,2 + + + + + Reactome:R-HSA-9028728 + NTRK2 phosphorylates FRS2 + + + + + Reactome:R-HSA-9029151 + JAK2 phosphorylates VAV1 in EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-Y-CRKL:RASGEF1:p-Y-SHC1:GRB2:VAV1 + + + + + Reactome:R-HSA-9029155 + JAK2 phosphorylates SHC1 in EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:p-CRKL:RABGEF1:SHC1 + + + + + Reactome:R-HSA-9032426 + NTRK2 phosphorylates FRS3 + + + + + Reactome:R-HSA-9032532 + NTRK2-bound FYN autophosphorylates + + + + + Reactome:R-HSA-9032601 + FYN-mediated phosphorylation of GRIN2B + + + + + Reactome:R-HSA-9032854 + NTRK2 phosphorylates CDK5 + + + + + Reactome:R-HSA-9033284 + NTRK2 promotes TIAM1 phosphorylation + + + + + Reactome:R-HSA-9034714 + NTRK3 dimers trans-autophosphorylate + + + + + Reactome:R-HSA-9034814 + NTRK3 phosphorylates PLCG1 + + + + + Reactome:R-HSA-9034875 + NTRK3 phosphorylates SHC1 + + + + + Reactome:R-HSA-9037040 + SRC,FYN phosphorylate NTRK2 + + + + + Reactome:R-HSA-909718 + Formation of p-STAT1 homodimer + + + + + Reactome:R-HSA-909726 + Phosphorylation of STAT1 + + + + + Reactome:R-HSA-909729 + Activation of JAK kinases + + + + + Reactome:R-HSA-909730 + Phosphorylation of INFAR1 by TYK2 + + + + + Reactome:R-HSA-909732 + Phosphorylation of STAT2 + + + + + Reactome:R-HSA-912629 + CBL is tyrosine phosphorylated + + + + + Reactome:R-HSA-9603420 + Activated NTRK3 promotes SRC autophosphorylation + + + + + Reactome:R-HSA-9604767 + FLT3LG dimer:FLT3 dimer autophosphorylates + + + + + Reactome:R-HSA-9606159 + BTK autophosphorylates + + + + + Reactome:R-HSA-9606162 + Phosphorylated BTK phosphorylates PLCG2 + + + + + Reactome:R-HSA-9606163 + p-SYK and LYN phosphorylate BTK + + + + + Reactome:R-HSA-9612085 + SRC phosphorylates GluN2 (GRIN2) subunits of NMDARs + + + + + Reactome:R-HSA-9612996 + NTRK1,2 in ADCYAP1(2-742):ADCYAP1R1:NTRK1,2 autophosphorylates + + + + + Reactome:R-HSA-9613023 + NTRK1,2 in Ade-Rib:ADORA2A:NTRK1,2 autophosphorylates + + + + + Reactome:R-HSA-9625487 + PTK2 autophosphorylates downstream of EGFR + + + + + Reactome:R-HSA-9634390 + ERBB2 homodimer phosphorylates SHC1 + + + + + Reactome:R-HSA-9664261 + Src phosphorylate SYK in IgG:Leishmania surface:p-FCGR3A:SYK + + + + + Reactome:R-HSA-9664275 + Src phosphorylates CD3 dimers in IgG:Lma antigens:FCGR3A:CD3 dimers + + + + + Reactome:R-HSA-9664278 + Phosphorylation and activation of PLCG due to FCGR3A effect + + + + + Reactome:R-HSA-9664588 + ERBB2 KD mutants trans-autophosphorylate + + + + + Reactome:R-HSA-9664976 + Phosphorylated heterodimers of ERBB2 KD mutants phosphorylate SHC1 + + + + + Reactome:R-HSA-9665032 + Phosphorylated heterodimers of ERBB2 KD mutants and EGFR phosphorylate PLCG1 + + + + + Reactome:R-HSA-9665389 + Heterodimers of ERBB2 ECD mutants and EGFR trans-autophosphorylate + + + + + Reactome:R-HSA-9665411 + Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR phosphorylate PLCG1 + + + + + Reactome:R-HSA-9665704 + Phosphorylated heterodimers of ERBB2 TMD/JMD mutants and EGFR phosphorylate PLCG1 + + + + + Reactome:R-HSA-9665705 + Phosphorylated heterodimers of ERBB2 TMD/JMD mutants phosphorylate SHC1 + + + + + Reactome:R-HSA-9665709 + ERBB2 TMD/JMD heterodimers trans-autophosphorylate + + + + + Reactome:R-HSA-9666425 + p-6Y-SYK phosphorylates VAV1,2,3 + + + + + Reactome:R-HSA-9669890 + Constitutive phosphorylation of kinase domain KIT mutants + + + + + Reactome:R-HSA-9669911 + Phosphorylation of juxtamembrane domain KIT mutants + + + + + Reactome:R-HSA-9670412 + Phosphorylation of STATs downstream of KIT mutants + + + + + Reactome:R-HSA-9670418 + Phosphorylation of JAK2 downstream of KIT mutants + + + + + Reactome:R-HSA-9672173 + Autophosphorylation of PDGFRA extracellular domain dimers + + + + + Reactome:R-HSA-9672175 + Autophosphorylation of PDGFR mutant dimers + + + + + Reactome:R-HSA-9673756 + Autophosphorylation of cytosolic PDGFRA and PDGFRB fusion proteins + + + + + Reactome:R-HSA-9673761 + Autophosphorylation of membrane-tethered fusions of PDGFRA or PDGFRB + + + + + Reactome:R-HSA-9680248 + Phosphorylation of extracellular domain KIT mutants + + + + + Reactome:R-HSA-9695834 + Constitutive phosphorylation of FLT3 mutants + + + + + Reactome:R-HSA-9698003 + FLT3 mutants phosphorylate GAB2 + + + + + Reactome:R-HSA-9698005 + FLT3 ITD mutants phosphorylate STAT5 + + + + + Reactome:R-HSA-9699578 + Active FLT3 phosphorylates CDKN1B + + + + + Reactome:R-HSA-9703437 + FLT3 fusion dimers autophosphorylate + + + + + Reactome:R-HSA-9703438 + FLT3 fusions phosphorylate GAB2 + + + + + Reactome:R-HSA-9706344 + FLT3 phosphorylates GRB10 + + + + + Reactome:R-HSA-9706350 + FLT3 phosphorylates CBL + + + + + Reactome:R-HSA-982807 + JAK2 phosphorylation of GHR + + + + + Reactome:R-HSA-983703 + p-6Y-SYK phosphorylates BLNK (SLP65) + + + + + Reactome:R-HSA-983707 + SYK autophosphorylates at the activated BCR + + + + + Reactome:R-HSA-983709 + LYN, FYN, BLK phosphorylate ITAMs of Ig-alpha (CD79A) and Ig-beta (CD79B) + + + + + + + + + + Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate. + EC:2.7.10.1 + MetaCyc:2.7.10.1-RXN + Reactome:R-HSA-166544 + Reactome:R-HSA-167019 + Reactome:R-HSA-167683 + Reactome:R-HSA-169905 + Reactome:R-HSA-177933 + Reactome:R-HSA-198295 + Reactome:R-HSA-6784324 + Reactome:R-HSA-74711 + Reactome:R-HSA-74715 + Reactome:R-HSA-74742 + Reactome:R-HSA-8852552 + Reactome:R-HSA-8853792 + Reactome:R-HSA-8950269 + Reactome:R-HSA-8950340 + Reactome:R-HSA-8950354 + Reactome:R-HSA-8950364 + Reactome:R-HSA-8950405 + Reactome:R-HSA-8950423 + Reactome:R-HSA-8950453 + Reactome:R-HSA-8950485 + Reactome:R-HSA-8950537 + Reactome:R-HSA-8950591 + Reactome:R-HSA-8950757 + Reactome:R-HSA-8982163 + Reactome:R-HSA-8983300 + Reactome:R-HSA-8983309 + Reactome:R-HSA-8983371 + Reactome:R-HSA-8983424 + Reactome:R-HSA-8986985 + Reactome:R-HSA-8986994 + Reactome:R-HSA-8986995 + Reactome:R-HSA-8987012 + Reactome:R-HSA-8987040 + Reactome:R-HSA-8987042 + Reactome:R-HSA-8987070 + Reactome:R-HSA-8987084 + Reactome:R-HSA-8987096 + Reactome:R-HSA-8987129 + Reactome:R-HSA-8987141 + Reactome:R-HSA-8987150 + Reactome:R-HSA-8987179 + Reactome:R-HSA-8987202 + Reactome:R-HSA-8987255 + molecular_function + receptor protein tyrosine kinase activity + receptor protein-tyrosine kinase activity + GO:0004714 + transmembrane receptor protein tyrosine kinase activity + + + + + Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate. + EC:2.7.10.1 + GOC:mah + + + + + EC:2.7.10.1 + skos:exactMatch + + + + + Reactome:R-HSA-166544 + TrkA receptor autophosphorylates + + + + + Reactome:R-HSA-167019 + SHC, complexed with TrkA, is tyrosine-phosphorylated + + + + + Reactome:R-HSA-167683 + TrkA phosphorylates PLCG1 + + + + + Reactome:R-HSA-169905 + ARMS is phosphorylated by active TrkA receptor + + + + + Reactome:R-HSA-177933 + SHC1 phosphorylation by phosphorylated EGFR + + + + + Reactome:R-HSA-198295 + TRKA phosphorylates IRS + + + + + Reactome:R-HSA-6784324 + p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA + + + + + Reactome:R-HSA-74711 + Phosphorylation of IRS + + + + + Reactome:R-HSA-74715 + Autophosphorylation of insulin receptor + + + + + Reactome:R-HSA-74742 + Phosphorylation of SHC1 + + + + + Reactome:R-HSA-8852552 + MST1R autophosphorylates + + + + + Reactome:R-HSA-8853792 + RET tyrosine phosphorylation + + + + + Reactome:R-HSA-8950269 + STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor + + + + + Reactome:R-HSA-8950340 + IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation + + + + + Reactome:R-HSA-8950354 + STAT4 is phosphorylated by p-JAK2 and/or p-Y-TYK2 after IL12:IL12R interaction + + + + + Reactome:R-HSA-8950364 + IL23R in IL23:IL23 receptor complex is phosphorylated + + + + + Reactome:R-HSA-8950405 + JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated + + + + + Reactome:R-HSA-8950423 + JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated + + + + + Reactome:R-HSA-8950453 + JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 + + + + + Reactome:R-HSA-8950485 + STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction + + + + + Reactome:R-HSA-8950537 + JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated + + + + + Reactome:R-HSA-8950591 + JAK2, TYK2 in IL23A:IL12B:IL23R:JAK2:IL12RB1:TYK2 are phosphorylated + + + + + Reactome:R-HSA-8950757 + IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated + + + + + Reactome:R-HSA-8982163 + IL19:IL20RA:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 + + + + + Reactome:R-HSA-8983300 + IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1 + + + + + Reactome:R-HSA-8983309 + IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates SHC1 + + + + + Reactome:R-HSA-8983371 + IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates STAT3 and STAT5 + + + + + Reactome:R-HSA-8983424 + IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1:GRB2:GAB2 phosphorylates GAB2 + + + + + Reactome:R-HSA-8986985 + IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 + + + + + Reactome:R-HSA-8986994 + IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 + + + + + Reactome:R-HSA-8986995 + IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA + + + + + Reactome:R-HSA-8987012 + IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 + + + + + Reactome:R-HSA-8987040 + IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 + + + + + Reactome:R-HSA-8987042 + IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 + + + + + Reactome:R-HSA-8987070 + IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 + + + + + Reactome:R-HSA-8987084 + IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1 + + + + + Reactome:R-HSA-8987096 + IL24:IL22RA1:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 + + + + + Reactome:R-HSA-8987129 + JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated + + + + + Reactome:R-HSA-8987141 + IL20:IL20RA:JAK1:IL20RB:p-JAK3,p-JAK2:STAT3 phosphorylates STAT3 + + + + + Reactome:R-HSA-8987150 + IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 + + + + + Reactome:R-HSA-8987179 + IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3 + + + + + Reactome:R-HSA-8987202 + IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 + + + + + Reactome:R-HSA-8987255 + IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 + + + + + receptor protein tyrosine kinase activity + EC:2.7.10.1 + + + + + receptor protein-tyrosine kinase activity + EC:2.7.10.1 + + + + + + + + + + + - - + + - - - - + + - regulation of lymphocyte proliferation + Binds to and stops, prevents or reduces the activity of an enzyme. + GO:0048551 + metalloenzyme inhibitor activity + molecular_function + GO:0004857 + This term should only be used in cases when the regulator directly interacts with the enzyme. + enzyme inhibitor activity + + + + Binds to and stops, prevents or reduces the activity of an enzyme. + GOC:ai + GOC:ebc + - + - + - + - - + + - - - - - - - - - - positive regulation of lymphocyte proliferation + Binds to and stops, prevents or reduces the activity of a protein kinase, an enzyme which phosphorylates a protein. + molecular_function + GO:0004860 + protein kinase inhibitor activity + + + + Binds to and stops, prevents or reduces the activity of a protein kinase, an enzyme which phosphorylates a protein. + GOC:ai + - + - + - + - - + + - - - + - - + + - negative regulation of lymphocyte proliferation + + + + + + + Combining with a glucocorticoid and transmitting the signal within the cell trigger a change in cell activity or function. + https://github.com/geneontology/go-ontology/issues/16717 + glucocorticoid receptor activity + molecular_function + GO:0004883 + nuclear glucocorticoid receptor activity + + + + Combining with a glucocorticoid and transmitting the signal within the cell trigger a change in cell activity or function. + GOC:signaling + PMID:17689856 + PMID:20920967 + - + - - - epithelial cell proliferation + + + Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction. + GO:0004926 + GO:0099600 + transmembrane receptor activity + Reactome:R-HSA-193672 + transmembrane signalling receptor activity + molecular_function + GO:0004888 + This term includes intracellular membrane receptors, e.g. IP3 triggered release of Ca2+ from intracellular stores. + transmembrane signaling receptor activity + + + + + Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction. + GOC:go_curators + Wikipedia:Transmembrane_receptor + + + + + transmembrane receptor activity + GOC:bf + GOC:signaling + + + + + Reactome:R-HSA-193672 + Sphingomyelinase is activated by the NGF:p75NTR complex + + + + + transmembrane signalling receptor activity + GOC:mah + + + + + + + + + + + + + + + Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. + GO:0001622 + GO:0001623 + GO:0001624 + GO:0001625 + GO:0016526 + Reactome:R-HSA-114552 + Reactome:R-HSA-114558 + Reactome:R-HSA-167408 + Wikipedia:GPCR + G protein coupled receptor activity + G protein linked receptor activity + G-protein coupled receptor activity + G-protein linked receptor activity + GPCR activity + ligand-dependent GPCR activity + receptor activity, G-protein coupled + EBV-induced receptor + Epstein-Barr Virus-induced receptor activity + G-protein coupled receptor activity, unknown ligand + Mas proto-oncogene receptor activity + RDC1 receptor activity + SREB receptor + orphan G protein coupled receptor activity + orphan G-protein coupled receptor activity + orphan GPCR activity + super conserved receptor expressed in brain receptor activity + molecular_function + GO:0004930 + + G protein-coupled receptor activity + + + + + Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. + GOC:bf + Wikipedia:GPCR + http://www.iuphar-db.org + + + + + Reactome:R-HSA-114552 + G12/13 activation by PAR + + + + + Reactome:R-HSA-114558 + Gq activation by PAR + + + + + Reactome:R-HSA-167408 + The high affinity receptor complex binds to G-protein + + + + + receptor activity, G-protein coupled + GOC:bf + + + + + + + + + + + + + + + + + + + + + + + + + + Combining with calcitonin and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. + molecular_function + GO:0004948 + calcitonin receptor activity + + + + Combining with calcitonin and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. + GOC:mah + GOC:signaling + PMID:21649645 + - + - + - + - - + + - + - - + + - regulation of epithelial cell proliferation + Combining with glucagon and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. + molecular_function + GO:0004967 + glucagon receptor activity + + + + Combining with glucagon and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. + GOC:mah + GOC:signaling + PMID:22438981 + - + - + - + - - + + - - + - - + + - positive regulation of epithelial cell proliferation + Combining with histamine to initiate a change in cell activity. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans. + molecular_function + GO:0004969 + histamine receptor activity + + + + Combining with histamine to initiate a change in cell activity. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans. + GOC:ai + - + - + - + - - + + - - - - + + - negative regulation of epithelial cell proliferation + + + + + + + Combining with the biogenic amine serotonin and transmitting the signal across the membrane by activating an associated G-protein. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates. + https://github.com/geneontology/go-ontology/issues/12942 + GO:0001585 + GO:0016609 + Wikipedia:5-HT_receptor + 5-HT receptor + 5-hydroxytryptamine receptor + G protein coupled serotonin receptor activity + G-protein coupled serotonin receptor activity + molecular_function + GO:0004993 + G protein-coupled serotonin receptor activity + + + + Combining with the biogenic amine serotonin and transmitting the signal across the membrane by activating an associated G-protein. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates. + GOC:ai + - + - + - + - - + + - - + - - + + - regulation of protein secretion + Combining with somatostatin to initiate a change in cell activity. Somatostatin is a peptide hormone that regulates the endocrine system by signaling via G protein-coupled somatostatin receptors. Somatostatin has two active forms produced by proteolytic cleavage: a 14 amino acid peptide (SST-14) and a 28 amino acid peptide (SST-28). + GHIH receptor activity + SRIF receptor activity + SST receptor activity + growth hormone-inhibiting hormone receptor activity + somatotrophin release inhibiting factor receptor activity + molecular_function + GO:0004994 + somatostatin receptor activity + + + + Combining with somatostatin to initiate a change in cell activity. Somatostatin is a peptide hormone that regulates the endocrine system by signaling via G protein-coupled somatostatin receptors. Somatostatin has two active forms produced by proteolytic cleavage: a 14 amino acid peptide (SST-14) and a 28 amino acid peptide (SST-28). + GOC:ai + GOC:bf + Wikipedia:Somatostatin + + + + + GHIH receptor activity + Wikipedia:Somatostatin + + + + + SRIF receptor activity + Wikipedia:Somatostatin + + + + + SST receptor activity + Wikipedia:Somatostatin + + + + + growth hormone-inhibiting hormone receptor activity + Wikipedia:Somatostatin + + + + + somatotrophin release inhibiting factor receptor activity + Wikipedia:Somatostatin + - + - + - + - - + + - - - - - - - - - - negative regulation of protein secretion + + Combining with vasopressin to initiate a change in cell activity. + GO:0016931 + vasopressin activated calcium mobilizing receptor activity + molecular_function + GO:0005000 + vasopressin receptor activity + + + + Combining with vasopressin to initiate a change in cell activity. + GOC:ai + - + - + - + - - + + - - - + + - - + + - positive regulation of protein secretion + + + + + + + + + + + + + + + + + + + Combining with insulin receptor ligand and transmitting the signal across the plasma membrane to initiate a change in cell activity. + https://github.com/geneontology/go-ontology/issues/23056 + insulin-activated receptor activity + molecular_function + GO:0005009 + insulin receptor activity + + + + Combining with insulin receptor ligand and transmitting the signal across the plasma membrane to initiate a change in cell activity. + ISBN:0198506732 + - + - + + + The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule. + Wikipedia:Binding_(molecular) + ligand + molecular_function + GO:0005488 + + + + Note that this term is in the subset of terms that should not be used for direct, manual gene product annotation. Please choose a more specific child term, or request a new one if no suitable term is available. For ligands that bind to signal transducing receptors, consider the molecular function term 'receptor binding ; GO:0005102' and its children. + binding + + + + + The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule. + GOC:ceb + GOC:mah + ISBN:0198506732 + + + + + + + - + - - + + - - - - - - - - - regulation of inflammatory response + Binding to a steroid, any of a large group of substances that have in common a ring system based on 1,2-cyclopentanoperhydrophenanthrene. + molecular_function + GO:0005496 + + steroid binding + + + + Binding to a steroid, any of a large group of substances that have in common a ring system based on 1,2-cyclopentanoperhydrophenanthrene. + GOC:jl + ISBN:0198506732 + - + - + - + - - + + - - - - - - - - - - negative regulation of inflammatory response + + Binding to a juvenile hormone, a sesquiterpenoid derivative that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis. + molecular_function + GO:0005500 + juvenile hormone binding + + + + Binding to a juvenile hormone, a sesquiterpenoid derivative that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis. + GOC:jl + ISBN:0198506732 + - + - + - + - - + + - - - - - - - - - - positive regulation of inflammatory response + Binding to an iron (Fe) ion. + iron binding + molecular_function + GO:0005506 + iron ion binding + + + + Binding to an iron (Fe) ion. + GOC:ai + - + - + - + - - + + - - - - - - - - - - - - - - - regulation of neurogenesis + Binding to a calcium ion (Ca2+). + molecular_function + calcium ion storage activity + GO:0005509 + calcium ion binding + + + + Binding to a calcium ion (Ca2+). + GOC:ai + - + - + - + - - + + - - - - - - - - - - negative regulation of neurogenesis + Binding to a protein. + GO:0001948 + GO:0045308 + protein amino acid binding + glycoprotein binding + molecular_function + GO:0005515 + + + + + + protein binding + + + + Binding to a protein. + GOC:go_curators + - + - + - + - - + + - - - - - - - - - - positive regulation of neurogenesis + Binding to collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%). + molecular_function + GO:0005518 + collagen binding + + + + Binding to collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%). + GOC:ai + ISBN:0198506732 + - + - + - + - - + + - - - - - - - - - regulation of immune response + Binding to D- or L-enantiomers of glucose. + molecular_function + GO:0005536 + glucose binding + + + + Binding to D- or L-enantiomers of glucose. + GOC:jl + - + - + - + - - + + - - - - - - - - - - negative regulation of immune response + + Binding to a glycan (polysaccharide) containing a substantial proportion of aminomonosaccharide residues. + molecular_function + GO:0005539 + + glycosaminoglycan binding + + + + Binding to a glycan (polysaccharide) containing a substantial proportion of aminomonosaccharide residues. + GOC:jl + ISBN:0198506732 + - + - + - + - - + + - - - - - - - - - - positive regulation of immune response + Binding to hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine. + hyaluronan binding + molecular_function + GO:0005540 + hyaluronic acid binding + + + + Binding to hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine. + GOC:jl + - + - - - - - - - - - - - - - - - - - - - - regulation of biological process + + + Binding to an odorant, any substance capable of stimulating the sense of smell. + molecular_function + GO:0005549 + + odorant binding + + + + Binding to an odorant, any substance capable of stimulating the sense of smell. + GOC:jl + ISBN:0721662544 + - + - + - + - - + + - + + Binding to a pheromone, a substance, or characteristic mixture of substances, that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process. + molecular_function + GO:0005550 + pheromone binding + + + + + Binding to a pheromone, a substance, or characteristic mixture of substances, that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process. + GOC:ai + + + + + + + + + + A location, relative to cellular compartments and structures, occupied by a macromolecular machine when it carries out a molecular function. There are two ways in which the gene ontology describes locations of gene products: (1) relative to cellular structures (e.g., cytoplasmic side of plasma membrane) or compartments (e.g., mitochondrion), and (2) the stable macromolecular complexes of which they are parts (e.g., the ribosome). + GO:0008372 + NIF_Subcellular:sao1337158144 + cell or subcellular entity + cellular component + cellular_component + subcellular entity + GO:0005575 + + + + + + + Note that, in addition to forming the root of the cellular component ontology, this term is recommended for use for the annotation of gene products whose cellular component is unknown. When this term is used for annotation, it indicates that no information was available about the cellular component of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. + cellular_component + + + + + A location, relative to cellular compartments and structures, occupied by a macromolecular machine when it carries out a molecular function. There are two ways in which the gene ontology describes locations of gene products: (1) relative to cellular structures (e.g., cytoplasmic side of plasma membrane) or compartments (e.g., mitochondrion), and (2) the stable macromolecular complexes of which they are parts (e.g., the ribosome). + GOC:pdt + NIF_Subcellular:sao1337158144 + + + + + subcellular entity + NIF_Subcellular:nlx_subcell_100315 + + + + + + + + + The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. + Wikipedia:Extracellular + extracellular + cellular_component + GO:0005576 + + + + + + + + + + + + Note that this term is intended to annotate gene products that are not attached to the cell surface. For gene products from multicellular organisms which are secreted from a cell but retained within the organism (i.e. released into the interstitial fluid or blood), consider the cellular component term 'extracellular space ; GO:0005615'. + extracellular region + + + + + The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite. + GOC:go_curators + + + + + + + + - - + + - regulation of developmental process + + + + + + + A highly soluble, elongated protein complex found in blood plasma and involved in clot formation. It is converted into fibrin monomer by the action of thrombin. In the mouse, fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of nonidentical chains (alpha, beta, and gamma) linked together by disulfide bonds. + fibrinogen + fibrinogen alpha chain + fibrinogen beta chain + fibrinogen gamma chain + cellular_component + GO:0005577 + fibrinogen complex + + + + A highly soluble, elongated protein complex found in blood plasma and involved in clot formation. It is converted into fibrin monomer by the action of thrombin. In the mouse, fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of nonidentical chains (alpha, beta, and gamma) linked together by disulfide bonds. + ISBN:0198547684 + - + - - - - - - - - - - - - - + + - - + + - regulation of cellular process + + + + + + + A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures. + Wikipedia:Collagen + cellular_component + GO:0005581 + collagen trimer + + + + A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures. + GOC:dos + GOC:mah + ISBN:0721639976 + PMID:19693541 + PMID:21421911 + - + - + - + - - + + - + - - + + - regulation of behavior + + + + + + + + Any triple helical collagen trimer that forms fibrils. + cellular_component + GO:0005583 + fibrillar collagen trimer + + + + Any triple helical collagen trimer that forms fibrils. + GOC:mah + ISBN:0721639976 + PMID:21421911 + - + - - - - - - - - - - - - - - + + + A collagen trimer containing alpha(I) chains. The most common form of type I collagen is a heterotrimer containing two alpha1(I) chains and one alpha2(I) chain; homotrimers containing three alpha1(I) chains are also found. Type I collagen triple helices associate to form banded fibrils. + Wikipedia:Collagen_type_I + cellular_component + GO:0005584 + collagen type I trimer + + + + + A collagen trimer containing alpha(I) chains. The most common form of type I collagen is a heterotrimer containing two alpha1(I) chains and one alpha2(I) chain; homotrimers containing three alpha1(I) chains are also found. Type I collagen triple helices associate to form banded fibrils. + GOC:mah + GOC:sl + ISBN:0721639976 + + + + + + + + + A collagen homotrimer of alpha1(II) chains; type II collagen triple helices associate to form fibrils. + Wikipedia:Collagen_type_II + cellular_component + GO:0005585 + collagen type II trimer + + + + + A collagen homotrimer of alpha1(II) chains; type II collagen triple helices associate to form fibrils. + ISBN:0721639976 + + + + + + + + + A collagen homotrimer of alpha1(III) chains; type III collagen triple helices associate to form fibrils. + cellular_component + GO:0005586 + collagen type III trimer + + + + + A collagen homotrimer of alpha1(III) chains; type III collagen triple helices associate to form fibrils. + ISBN:0721639976 + + + + + + + + + + - - + + - regulation of insulin secretion + + + + + + + A collagen heterotrimer containing type IV alpha chains; [alpha1(IV)]2alpha2(IV) trimers are commonly observed, although more type IV alpha chains exist and may be present in type IV trimers; type IV collagen triple helices associate to form 3 dimensional nets within basement membranes. + Wikipedia:Collagen_type_IV + cellular_component + GO:0005587 + collagen type IV trimer + + + + A collagen heterotrimer containing type IV alpha chains; [alpha1(IV)]2alpha2(IV) trimers are commonly observed, although more type IV alpha chains exist and may be present in type IV trimers; type IV collagen triple helices associate to form 3 dimensional nets within basement membranes. + ISBN:0721639976 + PMID:19693541 + PMID:21421911 + - + - - - ion homeostasis + + + A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers. + GO:0005605 + GO:0008003 + Wikipedia:Basement_membrane + cellular_component + basal lamina + basement lamina + lamina densa + GO:0005604 + Note that this term has no relationship to 'membrane ; GO:0016020' because the basement membrane is not a lipid bilayer. + basement membrane + + + + A collagen-containing extracellular matrix consisting of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers. + ISBN:0198547684 + PMID:22505934 + - + - - - - - - - - - - - - - - - circadian sleep/wake cycle, sleep + + + + + + + + + That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. + NIF_Subcellular:sao1425028079 + cellular_component + intercellular space + GO:0005615 + + + + + Note that for multicellular organisms, the extracellular space refers to everything outside a cell, but still within the organism (excluding the extracellular matrix). Gene products from a multi-cellular organism that are secreted from a cell into the interstitial fluid or blood can therefore be annotated to this term. + extracellular space + + + + That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid. + ISBN:0198547684 + - + - - - - - - - - - - - - - - + + - - + + + + + A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm. + https://github.com/geneontology/go-ontology/issues/17776 + Wikipedia:Intracellular + internal to cell + intracellular + protoplasm + cellular_component + nucleocytoplasm + protoplast + GO:0005622 + + + + + intracellular anatomical structure + + + + + A component of a cell contained within (but not including) the plasma membrane. In eukaryotes it includes the nucleus and cytoplasm. + ISBN:0198506732 + + + + + nucleocytoplasm + GOC:mah + + + + + protoplast + GOC:mah + + + + + + + + + + + + - regulation of steroid biosynthetic process + + + + + + + + + + + + + + A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. + NIF_Subcellular:sao1702920020 + Wikipedia:Cell_nucleus + cell nucleus + horsetail nucleus + cellular_component + GO:0005634 + + + + + + + + + + + + nucleus + + + + A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent. + GOC:go_curators + + + + + horsetail nucleus + GOC:al + GOC:mah + GOC:vw + PMID:15030757 + - + - - - coagulation + + + + + + + + + + + + + + + The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space). + GO:0005636 + Wikipedia:Nuclear_envelope + cellular_component + GO:0005635 + + + + nuclear envelope + + + + The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space). + ISBN:0198547684 + - + - + - + - - + + - + + - - + + - regulation of coagulation + The outer, i.e. cytoplasm-facing, lipid bilayer of the nuclear envelope; continuous with the endoplasmic reticulum of the cell and sometimes studded with ribosomes. + NIF_Subcellular:sao1617136075 + nucleus outer envelope + perinuclear membrane + cellular_component + GO:0005640 + nuclear outer membrane + + + + The outer, i.e. cytoplasm-facing, lipid bilayer of the nuclear envelope; continuous with the endoplasmic reticulum of the cell and sometimes studded with ribosomes. + ISBN:0198547684 + - + - - - - - - - - - - - - - - + + - - + + - negative regulation of coagulation + The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. + https://github.com/geneontology/go-ontology/issues/23023 + Wikipedia:Cytoplasm + cellular_component + GO:0005737 + + + + + + + + cytoplasm + + + + The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. + ISBN:0198547684 + - + - - - - - - - - - - - - - - + + - - + + - positive regulation of coagulation + A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol. + Wikipedia:Vacuole + cellular_component + vacuolar carboxypeptidase Y + GO:0005773 + + + + + + + + + + + vacuole + + + + A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol. + GOC:mtg_sensu + ISBN:0198506732 + - + - + - + - - + + - + - - + + - regulation of T cell activation + The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell. + cellular_component + GO:0005774 + vacuolar membrane + + + + The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell. + GOC:ai + - + - - - - - - - - - - - - - + + - - + + - regulation of B cell activation + + + + + + + + + + + + + + + + + + + A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. + Golgi + NIF_Subcellular:sao451912436 + Wikipedia:Golgi_apparatus + Golgi complex + Golgi ribbon + cellular_component + GO:0005794 + + + + + + + + + + Note that the Golgi apparatus can be located in various places in the cytoplasm. In plants and lower animal cells, the Golgi apparatus exists as many copies of discrete stacks dispersed throughout the cytoplasm, while the Golgi apparatus of interphase mammalian cells is a juxtanuclear, often pericentriolar reticulum, where the discrete Golgi stacks are stitched together to form a compact and interconnected ribbon, sometimes called the Golgi ribbon. + Golgi apparatus + + + + A membrane-bound cytoplasmic organelle of the endomembrane system that further processes the core oligosaccharides (e.g. N-glycans) added to proteins in the endoplasmic reticulum and packages them into membrane-bound vesicles. The Golgi apparatus operates at the intersection of the secretory, lysosomal, and endocytic pathways. + ISBN:0198506732 + - + - - - - - - - - - - - - - + + + Any vesicle associated with the Golgi complex and involved in mediating transport within the Golgi or between the Golgi and other parts of the cell. + NIF_Subcellular:sao819927218 + cellular_component + Golgi vesicle + vesicular component + GO:0005798 + Note that this definition includes vesicles that are transiently associated with the Golgi. + Golgi-associated vesicle + + + + + Any vesicle associated with the Golgi complex and involved in mediating transport within the Golgi or between the Golgi and other parts of the cell. + GOC:mah + + + + + vesicular component + NIF_Subcellular:sao138219748 + + + + + + + + + A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles. + Wikipedia:Cytoskeleton + cellular_component + GO:0005856 + + + + + + + + + + + + cytoskeleton + + + + + A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles. + GOC:mah + PMID:16959967 + PMID:27419875 + + + + + + + + - - + + - regulation of cell activation + + + + + + + Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle. + NIF_Subcellular:sao1846835077 + Wikipedia:Microtubule + microtubuli + microtubulus + neurotubule + cellular_component + GO:0005874 + + microtubule + + + + Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle. + ISBN:0879693568 + + + + + neurotubule + NIF_Subcellular:sao248349196 + - + - + - + - - + + - - + - - + + - negative regulation of cell activation + A microtubule in the axoneme of a eukaryotic cilium or flagellum; an axoneme contains nine modified doublet microtubules, which may or may not surround a pair of single microtubules. + cellular_component + GO:0005879 + axonemal microtubule + + + + A microtubule in the axoneme of a eukaryotic cilium or flagellum; an axoneme contains nine modified doublet microtubules, which may or may not surround a pair of single microtubules. + GOC:cilia + ISBN:0815316194 + - + - + - + - - + + - - + - - + + - positive regulation of cell activation + Any microtubule in the nucleus of a cell. + cellular_component + GO:0005880 + nuclear microtubule + + + + Any microtubule in the nucleus of a cell. + GOC:mah + - + - + - + - - + + - - - + - - + + - negative regulation of T cell activation + Any microtubule in the cytoplasm of a cell. + non-spindle-associated astral microtubule + cellular_component + GO:0005881 + cytoplasmic microtubule + + + + Any microtubule in the cytoplasm of a cell. + GOC:mah + - + - - - - - - - - - - - - - - + + - - + + - negative regulation of B cell activation + + + + + + + A cytoskeletal structure that forms a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: Type I, acidic keratins; Type II, basic keratins; Type III, including desmin, vimentin and others; Type IV, neurofilaments and related filaments; and Type V, lamins. + FMA:63851 + NIF_Subcellular:sao952483289 + Wikipedia:Intermediate_filament + cellular_component + intermediate filament associated protein + type I intermediate filament associated protein + type II intermediate filament associated protein + GO:0005882 + intermediate filament + + + + A cytoskeletal structure that forms a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: Type I, acidic keratins; Type II, basic keratins; Type III, including desmin, vimentin and others; Type IV, neurofilaments and related filaments; and Type V, lamins. + ISBN:0198506732 + http://www.cytochemistry.net/Cell-biology/intermediate_filaments.htm + - + - + + + + + + + + + + + + + + + A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane. + FMA:63850 + NIF_Subcellular:sao1588493326 + Wikipedia:Actin + microfilament + cellular_component + GO:0005884 + actin filament + + + + + A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane. + GOC:mah + ISBN:0198506732 + PMID:10666339 + + + + + + + + + + + + + + + The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. + GO:0005904 + juxtamembrane + NIF_Subcellular:sao1663586795 + Wikipedia:Cell_membrane + cell membrane + cellular membrane + cytoplasmic membrane + plasmalemma + bacterial inner membrane + inner endospore membrane + plasma membrane lipid bilayer + cellular_component + GO:0005886 + + + + + + + + + + + plasma membrane + + + + + The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. + ISBN:0716731363 + + + + + cellular membrane + NIF_Subcellular:sao6433132645 + + + + + plasma membrane lipid bilayer + GOC:mah + + + + + + + - + - - + + - - - - - - - - - - positive regulation of T cell activation + + The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. + integral to plasma membrane + cellular_component + GO:0005887 + integral component of plasma membrane + + + + The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. + GOC:dos + GOC:go_curators + - + - + - + - - + + - - + - - + + - positive regulation of B cell activation - - - - - - - - - nervous system process - - - - - - - - - regulation of body fluid levels + + + + + + + + + + + + + + + + + + + A disulfide-bonded, heterotetrameric receptor complex. The alpha chains are entirely extracellular, while each beta chain has one transmembrane domain. The ligand binds to the alpha subunit extracellular domain and the kinase is associated with the beta subunit intracellular domain. + cellular_component + GO:0005899 + insulin receptor complex + + + + A disulfide-bonded, heterotetrameric receptor complex. The alpha chains are entirely extracellular, while each beta chain has one transmembrane domain. The ligand binds to the alpha subunit extracellular domain and the kinase is associated with the beta subunit intracellular domain. + ISBN:0198506732 + - + - - - multicellular organismal movement + + + + + + + + + + + + + + + Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. Present in especially large numbers on the absorptive surface of intestinal cells. + NIF_Subcellular:sao671419673 + Wikipedia:Microvillus + cellular_component + microvilli + GO:0005902 + + Note that this term refers to a projection from a single cell, and should not be confused with 'microvillus' as used to refer to a multicellular structure such as that found in the placenta. + microvillus + + + + Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. Present in especially large numbers on the absorptive surface of intestinal cells. + ISBN:0815316194 + + + + + microvilli + NIF_Subcellular:sao671419673 + - + - - - - musculoskeletal movement + + + A cell junction that forms a connection between two or more cells of an organism; excludes direct cytoplasmic intercellular bridges, such as ring canals in insects. + https://github.com/geneontology/go-ontology/issues/22122 + cell-cell contact region + cell-cell contact zone + NIF_Subcellular:sao1922892319 + intercellular junction + cellular_component + GO:0005911 + cell-cell junction + + + + A cell junction that forms a connection between two or more cells of an organism; excludes direct cytoplasmic intercellular bridges, such as ring canals in insects. + GOC:aruk + GOC:bc + GOC:dgh + GOC:hb + GOC:mah + PMID:21422226 + PMID:28096264 + + + + + intercellular junction + NIF_Subcellular:sao1395777368 + - + - - + + - - + + - neuromuscular process controlling posture + An occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet; the outer leaflets of the two interacting plasma membranes are seen to be tightly apposed where sealing strands are present. Each sealing strand is composed of a long row of transmembrane adhesion proteins embedded in each of the two interacting plasma membranes. + NIF_Subcellular:sao1939999134 + Wikipedia:Tight_junction + zonula occludens + cellular_component + GO:0005923 + bicellular tight junction + + + + An occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet; the outer leaflets of the two interacting plasma membranes are seen to be tightly apposed where sealing strands are present. Each sealing strand is composed of a long row of transmembrane adhesion proteins embedded in each of the two interacting plasma membranes. + GOC:mah + ISBN:0815332181 + - + - - + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + - + - neuromuscular process controlling balance + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body. + + + + + + + GO:0072372 + FMA:67181 + NIF_Subcellular:sao787716553 + Wikipedia:Cilium + eukaryotic flagellum + microtubule-based flagellum + primary cilium + cellular_component + flagellum + GO:0005929 + + + + + Note that we deem cilium and microtubule-based flagellum to be equivalent. In most eukaryotic species, intracellular sub-components of the cilium, such as the ciliary base and rootlet, are located near the plasma membrane. In Diplomonads such as Giardia, instead, the same ciliary parts are located further intracellularly. Also, 'cilium' may be used when axonemal structure and/or motility are unknown, or when axonemal structure is unusual. For all other cases, please refer to children of 'cilium'. Finally, note that any role of ciliary proteins in sensory events should be captured by annotating to relevant biological process terms. + cilium + + + + A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body. + GOC:cilia + GOC:curators + GOC:kmv + GOC:vw + ISBN:0198547684 + PMID:16824949 + PMID:17009929 + PMID:20144998 + - + - - - endocrine process - + + + + + + + + + + + + + + + + + + + + + + + + + + + The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements. + GO:0035085 + GO:0035086 + Wikipedia:Axoneme + ciliary axoneme + cilium axoneme + flagellar axoneme + flagellum axoneme + cellular_component + GO:0005930 + + Note that cilia and eukaryotic flagella are deemed to be equivalent. In diplomonad species, such as Giardia, the axoneme may extend intracellularly up to 5um away from the plane of the plasma membrane. + axoneme + + + + + The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements. + GOC:bf + GOC:cilia + ISBN:0198547684 + - + - - - cognition + + + + + + + + + + + + + The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins. + Wikipedia:Cell_cortex + cellular_component + cell periphery + peripheral cytoplasm + GO:0005938 + + + cell cortex + + + + The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins. + GOC:mah + ISBN:0815316194 + - + - - - - - multicellular organismal water homeostasis + + + + + + + + + + + + + + The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. + https://github.com/geneontology/go-ontology/issues/22880 + jl + 2012-10-23T15:40:34Z + GO:0044261 + GO:0044723 + Wikipedia:Carbohydrate_metabolism + carbohydrate metabolism + biological_process + GO:0005975 + + + + + + + + + + + + carbohydrate metabolic process + + + + The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. + GOC:mah + ISBN:0198506732 + - + - - - response to stimulus + + + + + + + + + + + + + The chemical reactions and pathways involving a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. + GO:0044263 + polysaccharide metabolism + glycan metabolic process + glycan metabolism + multicellular organismal polysaccharide metabolic process + biological_process + GO:0005976 + + polysaccharide metabolic process + + + + The chemical reactions and pathways involving a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. + ISBN:0198547684 + - + - - - neuromuscular process + + + + + + + + + + + + + + + + The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages. + glycogen metabolism + biological_process + GO:0005977 + glycogen metabolic process + + + + The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages. + ISBN:0198506732 + - + - + - + - - + + - - - - - - - - detection of stimulus involved in sensory perception + + + The chemical reactions and pathways resulting in the formation of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues. + MetaCyc:GLYCOGENSYNTH-PWY + glycogen anabolism + glycogen biosynthesis + glycogen formation + glycogen synthesis + biological_process + GO:0005978 + glycogen biosynthetic process + + + + The chemical reactions and pathways resulting in the formation of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues. + ISBN:0198506732 + - + - + - + - - + + - - - - - - - - - detection of chemical stimulus involved in sensory perception + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen. + regulation of glycogen anabolism + regulation of glycogen biosynthesis + regulation of glycogen formation + regulation of glycogen synthesis + biological_process + GO:0005979 + regulation of glycogen biosynthetic process + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen. + GOC:go_curators + - + - + - + - - + + - - - - - - - - - detection of light stimulus involved in visual perception + + + + + The chemical reactions and pathways resulting in the breakdown of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues. + MetaCyc:GLYCOCAT-PWY + glycogen breakdown + glycogen catabolism + glycogen degradation + glycogenolysis + biological_process + GO:0005980 + glycogen catabolic process + + + + The chemical reactions and pathways resulting in the breakdown of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues. + ISBN:0198506732 + + + + + glycogenolysis + GOC:sl + - + - - - sensory perception of taste + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen. + regulation of glycogen breakdown + regulation of glycogen catabolism + regulation of glycogen degradation + regulation of glycogenolysis + biological_process + GO:0005981 + regulation of glycogen catabolic process + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen. + GOC:go_curators + + + + + regulation of glycogenolysis + GOC:sl + - + - + - + - - + + - - - - - - - - - detection of mechanical stimulus involved in sensory perception of sound + + + The chemical reactions and pathways involving monosaccharides, the simplest carbohydrates. They are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides. + monosaccharide metabolism + biological_process + GO:0005996 + monosaccharide metabolic process + + + + The chemical reactions and pathways involving monosaccharides, the simplest carbohydrates. They are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides. + ISBN:0198506732 + - + - + - + - - + + - - - - - - - - detection of chemical stimulus involved in sensory perception of smell + + The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides. + cellular glucose metabolic process + glucose metabolism + biological_process + GO:0006006 + glucose metabolic process + + + + The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides. + ISBN:0198506732 + + + + + cellular glucose metabolic process + GOC:vw + - + - + - + - - + + - - - - - - - - detection of chemical stimulus involved in sensory perception of taste + The chemical reactions and pathways resulting in the breakdown of glucose, the aldohexose gluco-hexose. + glucose breakdown + glucose catabolism + glucose degradation + biological_process + GO:0006007 + glucose catabolic process + + + + The chemical reactions and pathways resulting in the breakdown of glucose, the aldohexose gluco-hexose. + GOC:ai + - + - - - sensory perception of temperature stimulus + + + + + + + + + + + + + + + + The chemical reactions and pathways involving aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages. + aminoglycan metabolism + biological_process + GO:0006022 + aminoglycan metabolic process + + + + The chemical reactions and pathways involving aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages. + GOC:ai + ISBN:0198506732 + - + - - - sensory perception of electrical stimulus - - - - - - - - - sensory perception of light stimulus - - - - - - - - - sensory perception of mechanical stimulus - - - - - - - - - electroception - - - - - - - - - - - - - - - equilibrioception - - - - - - - - - echolocation - - - - - - - + - + - - + + - - - - - - - - - detection of temperature stimulus involved in sensory perception + + + + + The chemical reactions and pathways resulting in the formation of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages. + aminoglycan anabolism + aminoglycan biosynthesis + aminoglycan formation + aminoglycan synthesis + biological_process + GO:0006023 + aminoglycan biosynthetic process + + + + The chemical reactions and pathways resulting in the formation of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages. + GOC:ai + ISBN:0198506732 + - + - + - + - - + + - - - - - - - - - detection of light stimulus involved in sensory perception + + + The chemical reactions and pathways resulting in the formation of glycosaminoglycans, any of a group of polysaccharides that contain amino sugars. + glycosaminoglycan anabolism + glycosaminoglycan biosynthesis + glycosaminoglycan formation + glycosaminoglycan synthesis + biological_process + GO:0006024 + glycosaminoglycan biosynthetic process + + + + The chemical reactions and pathways resulting in the formation of glycosaminoglycans, any of a group of polysaccharides that contain amino sugars. + ISBN:0192800981 + - + - + - + - - + + - - - - - - - - - detection of electrical stimulus involved in sensory perception + The chemical reactions and pathways resulting in the breakdown of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages. + aminoglycan breakdown + aminoglycan catabolism + aminoglycan degradation + biological_process + GO:0006026 + aminoglycan catabolic process + + + + The chemical reactions and pathways resulting in the breakdown of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages. + GOC:ai + ISBN:0198506732 + - + - + - + - - + + - - - - - - - - detection of electrical stimulus involved in electroception + The chemical reactions and pathways resulting in the breakdown of glycosaminoglycans, any one of a group of polysaccharides that contain amino sugars. + glycosaminoglycan breakdown + glycosaminoglycan catabolism + glycosaminoglycan degradation + biological_process + GO:0006027 + glycosaminoglycan catabolic process + + + + The chemical reactions and pathways resulting in the breakdown of glycosaminoglycans, any one of a group of polysaccharides that contain amino sugars. + ISBN:0192800981 + - + - + - + - - + + - - - detection of temperature stimulus involved in sensory perception of pain + The chemical reactions and pathways involving proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans. + proteoglycan metabolism + proteoglycan sulfate transfer + biological_process + GO:0006029 + proteoglycan metabolic process + + + + The chemical reactions and pathways involving proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans. + GOC:mah + ISBN:0198506732 + - + - + - + - - + + - - - detection of mechanical stimulus involved in sensory perception of pain + The chemical reactions and pathways involving chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues. + beta-1,4-linked N-acetylglucosamine metabolic process + beta-1,4-linked N-acetylglucosamine metabolism + chitin metabolism + biological_process + GO:0006030 + chitin metabolic process + + + + The chemical reactions and pathways involving chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues. + GOC:jl + ISBN:0198506732 + - + - + - + - - + + - - - detection of electrical stimulus involved in sensory perception of pain + The chemical reactions and pathways resulting in the formation of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues. + beta-1,4-linked N-acetylglucosamine biosynthesis + beta-1,4-linked N-acetylglucosamine biosynthetic process + chitin anabolism + chitin biosynthesis + chitin formation + chitin synthesis + biological_process + GO:0006031 + chitin biosynthetic process + + + + The chemical reactions and pathways resulting in the formation of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues. + GOC:jl + ISBN:0198506732 + - + - + - + - - + + - - - detection of chemical stimulus involved in sensory perception of pain + The chemical reactions and pathways resulting in the breakdown of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues. + beta-1,4-linked N-acetylglucosamine catabolic process + beta-1,4-linked N-acetylglucosamine catabolism + chitin breakdown + chitin catabolism + chitin degradation + biological_process + GO:0006032 + chitin catabolic process + + + + The chemical reactions and pathways resulting in the breakdown of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues. + GOC:jl + ISBN:0198506732 + - + - + + + + The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues, occurring at the level of an individual cell. + cellular glucan metabolism + biological_process + GO:0006073 + cellular glucan metabolic process + + + + + The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues, occurring at the level of an individual cell. + ISBN:0198547684 + + + + + + + - + - - + + - - - - - - - - detection of mechanical stimulus involved in echolocation + + + + + The chemical reactions and pathways involving aldehydes, any organic compound with the formula R-CH=O, as carried out by individual cells. + aldehyde metabolism + alkanal metabolic process + alkanal metabolism + biological_process + GO:0006081 + + cellular aldehyde metabolic process + + + + The chemical reactions and pathways involving aldehydes, any organic compound with the formula R-CH=O, as carried out by individual cells. + GOC:go_curators + ISBN:0198506732 + - + - + - + - - + + - - - - - - - - detection of mechanical stimulus involved in equilibrioception + + + + + The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage. + organic acid metabolism + biological_process + GO:0006082 + + organic acid metabolic process + + + + The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage. + ISBN:0198506732 + - + - + + + The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances. + energy pathways + biological_process + intermediary metabolism + metabolic energy generation + GO:0006091 + + + + + + + + + + + generation of precursor metabolites and energy + + + + + The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances. + GOC:jl + + + + + intermediary metabolism + GOC:mah + + + + + + + - + - - + + - - - - - - - - - detection of mechanical stimulus involved in sensory perception + The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol. + MetaCyc:GLUCONEO-PWY + Wikipedia:Gluconeogenesis + glucose biosynthesis + glucose biosynthetic process + biological_process + GO:0006094 + gluconeogenesis + + + + The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol. + MetaCyc:GLUCONEO-PWY + - + - - - sensory perception of touch + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving carbohydrates. + regulation of carbohydrate metabolism + biological_process + GO:0006109 + regulation of carbohydrate metabolic process + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving carbohydrates. + GOC:go_curators + - + - + - + - - + + - - - - - - - - detection of mechanical stimulus involved in sensory perception of touch + Any process that modulates the frequency, rate or extent of gluconeogenesis, the formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol. + tb + 2013-01-18T12:47:43Z + GO:0090526 + regulation of glucose biosynthesis + regulation of glucose biosynthetic process + biological_process + regulation of gluconeogenesis involved in cellular glucose homeostasis + GO:0006111 + regulation of gluconeogenesis + + + + Any process that modulates the frequency, rate or extent of gluconeogenesis, the formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol. + GOC:go_curators + - + - - - - detection of electrical stimulus + + + The chemical reactions and pathways by which a cell derives energy from stored compounds such as fats or glycogen. + energy reserve metabolism + biological_process + GO:0006112 + + energy reserve metabolic process + + + + The chemical reactions and pathways by which a cell derives energy from stored compounds such as fats or glycogen. + GOC:mah + - + - - - - - detection of mechanical stimulus + + + + The process of introducing a phosphate group on to a protein. + protein amino acid phosphorylation + biological_process + GO:0006468 + + protein phosphorylation + + + + The process of introducing a phosphate group on to a protein. + GOC:hb + + + + + protein amino acid phosphorylation + GOC:bf + - + - + - - + + - - - - - - - - regulation of secretion + + Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase activity. + down regulation of protein kinase activity + down-regulation of protein kinase activity + downregulation of protein kinase activity + inhibition of protein kinase activity + biological_process + GO:0006469 + negative regulation of protein kinase activity + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase activity. + GOC:go_curators + - + - + - + - - + + - - - - - - - - - positive regulation of secretion + + The chemical reactions and pathways resulting in the breakdown of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. + glycoprotein breakdown + glycoprotein catabolism + glycoprotein degradation + biological_process + GO:0006516 + glycoprotein catabolic process + + + + The chemical reactions and pathways resulting in the breakdown of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. + GOC:go_curators + ISBN:0198506732 + - + - + - + - - + + - - - - - - - - - negative regulation of secretion + The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. + peptide metabolism + biological_process + GO:0006518 + + peptide metabolic process + + + + The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. + GOC:go_curators + - + - + - + - - + + - - - - - - - - regulation of transport + + + + The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells. + GO:0006519 + amino acid and derivative metabolism + amino acid metabolic process + cellular amino acid and derivative metabolic process + cellular amino acid metabolism + biological_process + GO:0006520 + + + + + + + + cellular amino acid metabolic process + + + + The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells. + ISBN:0198506732 + - + - + - - + + - - - - - - - - - positive regulation of transport + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids. + regulation of amino acid metabolism + biological_process + GO:0006521 + regulation of cellular amino acid metabolic process + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids. + GOC:go_curators + - + - + - + - - + + - - - - - - - - - negative regulation of transport + + + The chemical reactions and pathways involving glutamate, the anion of 2-aminopentanedioic acid. + Wikipedia:Glutamic_acid + glutamate metabolism + glutamic acid metabolic process + glutamic acid metabolism + biological_process + GO:0006536 + glutamate metabolic process + + + + The chemical reactions and pathways involving glutamate, the anion of 2-aminopentanedioic acid. + GOC:go_curators + - + - + - + - - + + - - - - - - - - - - negative regulation of lipid biosynthetic process + + The chemical reactions and pathways resulting in the formation of glutamate, the anion of 2-aminopentanedioic acid. + glutamate anabolism + glutamate biosynthesis + glutamate formation + glutamate synthesis + glutamic acid biosynthesis + glutamic acid biosynthetic process + glutamate biosynthesis, using glutamate dehydrogenase (NAD(P)+) + glutamate biosynthesis, using glutamate synthase (NADPH) + glutamate biosynthetic process, using glutamate dehydrogenase (NAD(P)+) + glutamate biosynthetic process, using glutamate synthase (NADPH) + biological_process + GO:0006537 + glutamate biosynthetic process + + + + The chemical reactions and pathways resulting in the formation of glutamate, the anion of 2-aminopentanedioic acid. + GOC:go_curators + - + - + - + - - + + - - - - - - - - - negative regulation of developmental process + + The chemical reactions and pathways resulting in the breakdown of glutamate, the anion of 2-aminopentanedioic acid. + GO:0019459 + glutamate breakdown + glutamate catabolism + glutamate degradation + glutamic acid catabolic process + glutamic acid catabolism + biological_process + glutamate deamidation + GO:0006538 + glutamate catabolic process + + + + The chemical reactions and pathways resulting in the breakdown of glutamate, the anion of 2-aminopentanedioic acid. + GOC:go_curators + - + - + - + - - + + - - - - - - - - - positive regulation of developmental process + + + The chemical reactions and pathways involving compounds derived from amino acids, organic acids containing one or more amino substituents. + amino acid derivative metabolic process + cellular amino acid derivative metabolic process + cellular amino acid derivative metabolism + cellular modified amino acid metabolism + modified amino acid metabolic process + modified amino acid metabolism + biological_process + GO:0006575 + + + + cellular modified amino acid metabolic process + + + + The chemical reactions and pathways involving compounds derived from amino acids, organic acids containing one or more amino substituents. + GOC:ai + + + + + cellular modified amino acid metabolism + GOC:mah + + + + + modified amino acid metabolic process + GOC:mah + + + + + modified amino acid metabolism + GOC:mah + - + - + + + The chemical reactions and pathways occurring at the level of individual cells involving any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters. + biogenic amine metabolism + biological_process + GO:0006576 + cellular biogenic amine metabolic process + + + + + The chemical reactions and pathways occurring at the level of individual cells involving any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters. + GOC:jl + ISBN:0395825172 + + + + + + + - + - - + + - - - - - - - - regulation of cellular component organization + + + The chemical reactions and pathways involving any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. + catecholamine metabolism + biological_process + GO:0006584 + catecholamine metabolic process + + + + The chemical reactions and pathways involving any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. + GOC:jl + ISBN:0198506732 + - + - + + + The formation of either of the compounds secreted by the thyroid gland, mainly thyroxine and triiodothyronine. This is achieved by the iodination and joining of tyrosine molecules to form the precursor thyroglobin, proteolysis of this precursor gives rise to the thyroid hormones. + biological_process + GO:0006590 + Note that this term does not fall under the general GO definition for biosynthetic processes, which is 'The chemical reactions and pathways resulting in the formation of... ', because thyroid hormones can only be formed by the proteolysis of a larger molecule (see term definition). The word 'generation' is therefore used in place of biosynthesis. + thyroid hormone generation + + + + + The formation of either of the compounds secreted by the thyroid gland, mainly thyroxine and triiodothyronine. This is achieved by the iodination and joining of tyrosine molecules to form the precursor thyroglobin, proteolysis of this precursor gives rise to the thyroid hormones. + GOC:jl + ISBN:0716720094 + + + + + + + - + - - + + - - - - - - - - - negative regulation of cellular component organization + + + + The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids. + Wikipedia:Lipid_metabolism + lipid metabolism + biological_process + GO:0006629 + + + + + + + + + + + + + lipid metabolic process + + + + The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids. + GOC:ma + - + - + - + - - + + - - - - - - - - - positive regulation of cellular component organization + The chemical reactions and pathways involving galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group. + galactosylceramide metabolism + biological_process + GO:0006681 + galactosylceramide metabolic process + + + + The chemical reactions and pathways involving galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group. + GOC:ai + - + - + - + - - + + - - - - - - - - regulation of nitrogen compound metabolic process + The chemical reactions and pathways resulting in the formation of galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group. + galactosylceramide anabolism + galactosylceramide biosynthesis + galactosylceramide formation + galactosylceramide synthesis + biological_process + GO:0006682 + galactosylceramide biosynthetic process + + + + The chemical reactions and pathways resulting in the formation of galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group. + GOC:ai + - + - + - + - - + + - - - - - - - - - negative regulation of nitrogen compound metabolic process + The chemical reactions and pathways resulting in the breakdown of galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group. + galactosylceramide breakdown + galactosylceramide catabolism + galactosylceramide degradation + biological_process + GO:0006683 + galactosylceramide catabolic process + + + + The chemical reactions and pathways resulting in the breakdown of galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group. + GOC:ai + - + - + - + - - + + - - - - - - - - - positive regulation of nitrogen compound metabolic process + + + + The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification. + Wikipedia:Steroid_metabolisms#Steroid_biosynthesis + steroid anabolism + steroid biosynthesis + steroid formation + steroid synthesis + steroidogenesis + biological_process + GO:0006694 + steroid biosynthetic process + + + + The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification. + GOC:go_curators + - + - - - localization + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of bile acids, any of a group of steroid carboxylic acids occurring in bile. + bile acid anabolism + bile acid biosynthesis + bile acid formation + bile acid synthesis + biological_process + GO:0006699 + bile acid biosynthetic process + + + + The chemical reactions and pathways resulting in the formation of bile acids, any of a group of steroid carboxylic acids occurring in bile. + GOC:go_curators + - + - - - - - - - - - - - - - - - cartilage development + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones. + C21-steroid hormone anabolism + C21-steroid hormone biosynthesis + C21-steroid hormone formation + C21-steroid hormone synthesis + biological_process + GO:0006700 + C21-steroid hormone biosynthetic process + + + + The chemical reactions and pathways resulting in the formation of C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones. + GOC:ai + - + - + - + - - + + - - - - - - - - - - positive regulation of protein transport + The chemical reactions and pathways resulting in the formation of progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants. + progesterone anabolism + progesterone biosynthesis + progesterone formation + progesterone synthesis + biological_process + GO:0006701 + progesterone biosynthetic process + + + + The chemical reactions and pathways resulting in the formation of progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants. + GOC:jl + http://www.cogsci.princeton.edu/ + - + - + - + - - + + - - - - - - - - - regulation of protein transport + + + The chemical reactions and pathways resulting in the formation of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. + glucocorticoid anabolism + glucocorticoid biosynthesis + glucocorticoid formation + glucocorticoid synthesis + biological_process + GO:0006704 + glucocorticoid biosynthetic process + + + + The chemical reactions and pathways resulting in the formation of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. + ISBN:0198506732 + - + - + - + - - + + - - - - - - - - - - negative regulation of protein transport + + + + The chemical reactions and pathways resulting in the formation of mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. + mineralocorticoid anabolism + mineralocorticoid biosynthesis + mineralocorticoid formation + mineralocorticoid synthesis + biological_process + GO:0006705 + mineralocorticoid biosynthetic process + + + + The chemical reactions and pathways resulting in the formation of mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. + ISBN:0198506732 + - + - - - establishment of localization + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. + steroid breakdown + steroid catabolism + steroid degradation + biological_process + GO:0006706 + steroid catabolic process + + + + The chemical reactions and pathways resulting in the breakdown of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. + GOC:go_curators + - + - + - + - - + + - - - - - - - - regulation of multicellular organismal process + The chemical reactions and pathways resulting in the breakdown of progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants. + progesterone breakdown + progesterone catabolism + progesterone degradation + biological_process + GO:0006709 + progesterone catabolic process + + + + The chemical reactions and pathways resulting in the breakdown of progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants. + GOC:jl + http://www.cogsci.princeton.edu/ + - + - + - + - - + + - - - - - - - - - positive regulation of multicellular organismal process + + The chemical reactions and pathways resulting in the breakdown of mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. + mineralocorticoid breakdown + mineralocorticoid catabolism + mineralocorticoid degradation + biological_process + GO:0006712 + mineralocorticoid catabolic process + + + + The chemical reactions and pathways resulting in the breakdown of mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. + ISBN:0198506732 + - + - + - + - - + + - - - - - - - - - negative regulation of multicellular organismal process + The chemical reactions and pathways resulting in the breakdown of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. + glucocorticoid breakdown + glucocorticoid catabolism + glucocorticoid degradation + biological_process + GO:0006713 + glucocorticoid catabolic process + + + + The chemical reactions and pathways resulting in the breakdown of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. + ISBN:0198506732 + - + - + - + - - + + - - - - - - - - regulation of lymphocyte activation + + The chemical reactions and pathways involving juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis. + juvenile hormone metabolism + biological_process + GO:0006716 + juvenile hormone metabolic process + + + + The chemical reactions and pathways involving juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis. + GOC:go_curators + ISBN:0198547684 + - + - + - + - - + + - - - - - - - - - negative regulation of lymphocyte activation + + The chemical reactions and pathways resulting in the formation of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis. + juvenile hormone anabolism + juvenile hormone biosynthesis + juvenile hormone formation + juvenile hormone synthesis + biological_process + GO:0006718 + juvenile hormone biosynthetic process + + + + The chemical reactions and pathways resulting in the formation of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis. + GOC:go_curators + ISBN:0198547684 + - + - + - + - - + + - - - - - - - - - positive regulation of lymphocyte activation + + The chemical reactions and pathways resulting in the breakdown of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis. + juvenile hormone breakdown + juvenile hormone catabolism + juvenile hormone degradation + biological_process + GO:0006719 + juvenile hormone catabolic process + + + + The chemical reactions and pathways resulting in the breakdown of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis. + GOC:go_curators + ISBN:0198547684 + - + - + - + - - + + - - - - - - - - - regulation of cellular component movement + + The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells. + aromatic compound metabolism + aromatic hydrocarbon metabolic process + aromatic hydrocarbon metabolism + biological_process + GO:0006725 + + cellular aromatic compound metabolic process + + + + The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells. + GOC:ai + ISBN:0198506732 + - + - + - + - - + + - - - - - - - - - negative regulation of cellular component movement + The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid. + phosphate metabolism + biological_process + phosphate metabolic process + GO:0006796 + phosphate-containing compound metabolic process + + + + The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid. + GOC:ai + - + - + - + - - + + - - - - - - - - - positive regulation of cellular component movement + + The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen. + nitrogen compound metabolism + biological_process + GO:0006807 + + + nitrogen compound metabolic process + + + + The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen. + GOC:jl + ISBN:0198506732 + - + - - - cell division + + + The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter, pore or motor protein. + jl + 2012-12-13T16:25:32Z + GO:0015457 + GO:0015460 + GO:0044765 + biological_process + single-organism transport + GO:0006810 + + + + + + + + Note that this term should not be used for direct annotation. It should be possible to make a more specific annotation to one of the children of this term, for e.g. to transmembrane transport, to microtubule-based transport or to vesicle-mediated transport. + transport + + + + The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter, pore or motor protein. + GOC:dos + GOC:dph + GOC:jl + GOC:mah + - + - + - + - - + + - - - - - - - - regulation of cell division + The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + biological_process + GO:0006811 + + + + ion transport + + + + The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:ai + - + - + - + - - + + - - - - - - - - - meiotic cell cycle + The directed movement of cations, atoms or small molecules with a net positive charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GO:0006819 + GO:0015674 + GO:0072512 + di-, tri-valent inorganic cation transport + trivalent inorganic cation transport + biological_process + GO:0006812 + cation transport + + + + The directed movement of cations, atoms or small molecules with a net positive charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:ai + + + + + di-, tri-valent inorganic cation transport + GOC:mah + - + - + - + - - + + - - - - - - - - proprioception involved in equilibrioception + The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GO:0006834 + GO:0016974 + sodium/potassium transport + sodium transport + mitochondrial sodium/calcium ion exchange + sodium:calcium exchange + sodium:solute transport + biological_process + sodium channel auxiliary protein activity + GO:0006814 + sodium ion transport + + + + The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:ai + + + + + sodium channel auxiliary protein activity + GOC:mah + - + - + - + - - + + - - - - - - - - visual perception involved in equilibrioception + The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + calcium transport + mitochondrial sodium/calcium ion exchange + sodium:calcium exchange + biological_process + GO:0006816 + calcium ion transport + + + + The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:ai + - + - + - + - - + + - - - - - - - - - regulation of meiotic cell cycle + The directed movement of iron (Fe) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + pr + 2012-04-18T03:33:45Z + GO:0015681 + GO:0015682 + GO:0015684 + GO:0033216 + GO:0097286 + iron transport + ferric ion import + ferric ion transport + ferric iron import + ferric iron transport + ferric iron uptake + ferrous ion transport + ferrous iron transport + biological_process + iron ion import + GO:0006826 + iron ion transport + + + + The directed movement of iron (Fe) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:ai + - + - + - + - - + + - - - - - - - - - - positive regulation of meiotic cell cycle + + The directed movement of water (H2O) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + biological_process + GO:0006833 + water transport + + + + The directed movement of water (H2O) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:ai + - + - + - + - - + + - - - - - - - - - - negative regulation of meiotic cell cycle + The directed movement of dicarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GO:0006841 + biological_process + sodium:dicarboxylate transport + GO:0006835 + dicarboxylic acid transport + + + + The directed movement of dicarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:krc + - + - - - response to electrical stimulus + + + + + + + + + + + + + + + + + + + + + + + + + + The directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell. + sodium:neurotransmitter transport + biological_process + GO:0006836 + + neurotransmitter transport + + + + The directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell. + GOC:ai + - + - - - detection of stimulus + + + + + + + + + + + + + The directed movement of serotonin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems. + biological_process + GO:0006837 + serotonin transport + + + + The directed movement of serotonin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems. + GOC:ai + - + - - - - localization of cell + + + + + + + + + + + + + The transport of substances that occurs outside cells. + biological_process + GO:0006858 + extracellular transport + + + + The transport of substances that occurs outside cells. + GOC:go_curators + - + - - - multi-organism process + + + + + + + + + + + + + The directed extracellular movement of amino acids. + biological_process + GO:0006860 + extracellular amino acid transport + + + + The directed extracellular movement of amino acids. + GOC:ai + - + - - - - cellular response to stimulus + + + + + + + + + + + + + The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GO:0006866 + biological_process + GO:0006865 + + + amino acid transport + + + + The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:ai + - + - + - + - - + + - - - + + - regulation of cell cycle + The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. + biological_process + GO:0006869 + + + + lipid transport + + + + The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. + ISBN:0198506732 + - + - + - + - - + + - - - - - - - - - positive regulation of cell division + Any process involved in the maintenance of an internal steady state of ions at the level of a cell. + biological_process + GO:0006873 + + cellular ion homeostasis + + + + Any process involved in the maintenance of an internal steady state of ions at the level of a cell. + GOC:mah + - + - + - + - - + + - - - - - - - - - negative regulation of cell division + + + Any process involved in the maintenance of an internal steady state of calcium ions at the level of a cell. + regulation of calcium ion concentration + biological_process + GO:0006874 + cellular calcium ion homeostasis + + + + Any process involved in the maintenance of an internal steady state of calcium ions at the level of a cell. + GOC:ceb + GOC:mah + - + - + - + - - + + - - - - - - - - regulation of nuclear division + + + Any process involved in the maintenance of an internal steady state of metal ions at the level of a cell. + cellular heavy metal ion homeostasis + biological_process + GO:0006875 + cellular metal ion homeostasis + + + + Any process involved in the maintenance of an internal steady state of metal ions at the level of a cell. + GOC:ai + GOC:mah + - + - + - + - - + + - - - - - - - - - negative regulation of nuclear division + + Any process involved in the maintenance of an internal steady state of iron ions at the level of a cell. + iron homeostasis + biological_process + GO:0006879 + cellular iron ion homeostasis + + + + Any process involved in the maintenance of an internal steady state of iron ions at the level of a cell. + GOC:ai + GOC:mah + - + - + - + - - + + - - - - - - - - - positive regulation of nuclear division + + + + Any process involved in the maintenance of an internal steady state of sodium ions at the level of a cell. + biological_process + GO:0006883 + cellular sodium ion homeostasis + + + + Any process involved in the maintenance of an internal steady state of sodium ions at the level of a cell. + GOC:ai + GOC:mah + - + - + - - + + - - - - - - - - regulation of sensory perception of pain + + Any process involved in maintaining the steady state of a cell's volume. The cell's volume refers to the three-dimensional space occupied by a cell. + regulation of cell volume + biological_process + GO:0006884 + cell volume homeostasis + + + + Any process involved in maintaining the steady state of a cell's volume. The cell's volume refers to the three-dimensional space occupied by a cell. + GOC:dph + GOC:go_curators + GOC:tb + + + + + regulation of cell volume + GOC:dph + GOC:tb + - + - + - - + + - - - - - - - - regulation of sensory perception - - - - - - - - - - catecholamine transport + + Any process involved in the maintenance of an internal equilibrium of hydrogen ions, thereby modulating the internal pH, within an organism or cell. + hydrogen ion homeostasis + biological_process + GO:0006885 + regulation of pH + + + + Any process involved in the maintenance of an internal equilibrium of hydrogen ions, thereby modulating the internal pH, within an organism or cell. + GOC:dph + GOC:go_curators + GOC:tb + + + + + hydrogen ion homeostasis + GOC:dph + GOC:tb + - + - + - + - - + + + + + + - - - + + - regulation of amine transport + The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell. + GO:0032779 + biological_process + copper-induced intracellular protein transport + GO:0006886 + + + intracellular protein transport + + + + The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell. + GOC:mah + + + + + copper-induced intracellular protein transport + GOC:al + - + - + - + - - + + - - + - - + + - negative regulation of amine transport + A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell. + GO:0016194 + GO:0016195 + Wikipedia:Exocytosis + vesicle exocytosis + biological_process + nonselective vesicle exocytosis + GO:0006887 + + exocytosis + + + + A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle. Exocytosis can occur either by full fusion, when the vesicle collapses into the plasma membrane, or by a kiss-and-run mechanism that involves the formation of a transient contact, a pore, between a granule (for exemple of chromaffin cells) and the plasma membrane. The latter process most of the time leads to only partial secretion of the granule content. Exocytosis begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when molecules are secreted from the cell. + GOC:mah + ISBN:0716731363 + PMID:22323285 + - + - - - - - - - - - - - - - - - - - - - - - positive regulation of amine transport + + + The directed movement of substances from the Golgi to other parts of the cell, including organelles and the plasma membrane, mediated by small transport vesicles. + post-Golgi transport + biological_process + GO:0006892 + post-Golgi vesicle-mediated transport + + + + The directed movement of substances from the Golgi to other parts of the cell, including organelles and the plasma membrane, mediated by small transport vesicles. + GOC:ai + GOC:mah + - + - + - + - - + + + + + + - - - - - - - - regulation of nervous system development + + The directed movement of substances from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane, where they fuse and release their contents by exocytosis. + Golgi to plasma membrane vesicle-mediated transport + biological_process + GO:0006893 + Golgi to plasma membrane transport + + + + The directed movement of substances from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane, where they fuse and release their contents by exocytosis. + ISBN:0716731363 + - + - + - + - - + + + + + + + + + + - - - + + + The directed movement of substances from the Golgi to the vacuole. + Golgi to vacuole vesicle-mediated transport + biological_process + GO:0006896 + Golgi to vacuole transport + + + + + The directed movement of substances from the Golgi to the vacuole. + GOC:ai + + + + + + + + - - + + - negative regulation of nervous system development + + + + + + + The process in which vesicles are directed to specific destination membranes. Targeting involves coordinated interactions among cytoskeletal elements (microtubules or actin filaments), motor proteins, molecules at the vesicle membrane and target membrane surfaces, and vesicle cargo. + biological_process + GO:0006903 + vesicle targeting + + + + The process in which vesicles are directed to specific destination membranes. Targeting involves coordinated interactions among cytoskeletal elements (microtubules or actin filaments), motor proteins, molecules at the vesicle membrane and target membrane surfaces, and vesicle cargo. + GOC:mah + PMID:17335816 + - + - + - + - - + + - - - + + + + - - + + - positive regulation of nervous system development - - - - - - - - - - - - - imidazole-containing compound metabolic process + Fusion of the membrane of a transport vesicle with its target membrane. + biological_process + GO:0006906 + vesicle fusion + + + + Fusion of the membrane of a transport vesicle with its target membrane. + GOC:jid + - + - - - - metal ion homeostasis + + + + + + + + + A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. + Wikipedia:Muscle_contraction + biological_process + GO:0006936 + + muscle contraction + + + + A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. + GOC:ef + GOC:mtg_muscle + ISBN:0198506732 + - + - - - - monovalent inorganic cation homeostasis + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of muscle contraction. + biological_process + GO:0006937 + regulation of muscle contraction + + + + Any process that modulates the frequency, rate or extent of muscle contraction. + GOC:go_curators + - + - - - - calcium ion homeostasis + + + + + + + + + + + + + + A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length. + visceral muscle contraction + biological_process + GO:0006939 + smooth muscle contraction + + + + A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length. + GOC:ef + GOC:jl + GOC:mtg_muscle + ISBN:0198506732 + - + - - - - sodium ion homeostasis + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of smooth muscle contraction. + biological_process + GO:0006940 + regulation of smooth muscle contraction + + + + Any process that modulates the frequency, rate or extent of smooth muscle contraction. + GOC:go_curators + - + - - - cation homeostasis + + + + + + + + + A process in which force is generated within striated muscle tissue, resulting in the shortening of the muscle. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Striated muscle is a type of muscle in which the repeating units (sarcomeres) of the contractile myofibrils are arranged in registry throughout the cell, resulting in transverse or oblique striations observable at the level of the light microscope. + sarcomeric muscle contraction + biological_process + GO:0006941 + striated muscle contraction + + + + A process in which force is generated within striated muscle tissue, resulting in the shortening of the muscle. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Striated muscle is a type of muscle in which the repeating units (sarcomeres) of the contractile myofibrils are arranged in registry throughout the cell, resulting in transverse or oblique striations observable at the level of the light microscope. + GOC:jl + GOC:mtg_muscle + ISBN:0198506732 + - + - + - + - - - - - - - - - regulation of cardiac muscle contraction + + Any process that modulates the frequency, rate or extent of striated muscle contraction. + biological_process + GO:0006942 + regulation of striated muscle contraction + + + + Any process that modulates the frequency, rate or extent of striated muscle contraction. + GOC:go_curators + - + - + - + - - + + - - - - - - - - - - negative regulation of cardiac muscle contraction + + + + The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane. Syncytia are normally derived from single cells that fuse or fail to complete cell division. + biological_process + GO:0006949 + + syncytium formation + + + + The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane. Syncytia are normally derived from single cells that fuse or fail to complete cell division. + ISBN:0198506732 + - + - - - - - - - - - vibrational conductance of sound to the inner ear + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). + biological_process + response to abiotic stress + response to biotic stress + GO:0006950 + + + + + + + Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. + response to stress + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). + GOC:mah + - + - - - reflex + + + Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack. + GO:0002217 + GO:0042829 + defence response + physiological defense response + biological_process + antimicrobial peptide activity + defense/immunity protein activity + GO:0006952 + defense response + + + + Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack. + GOC:go_curators + - + - - - vestibular reflex + + + + + + + + + + + + + + + The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages. + inflammation + Wikipedia:Inflammation + biological_process + GO:0006954 + + inflammatory response + + + + The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages. + GO_REF:0000022 + ISBN:0198506732 + - + - - - linear vestibuloocular reflex + + + + Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. + biological_process + GO:0006955 + + immune response + + + + Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. + GOC:add + GO_REF:0000022 + - + - - - - - - - - - heart contraction + + + + + + + + + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. + jl + 2013-12-19T15:25:51Z + GO:1902589 + organelle organisation + single organism organelle organization + biological_process + organelle organization and biogenesis + single-organism organelle organization + GO:0006996 + + + organelle organization + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. + GOC:mah + + + + + single organism organelle organization + GOC:TermGenie + + + + + organelle organization and biogenesis + GOC:dph + GOC:jl + GOC:mah + - + - - - - - - - - - cardiac muscle contraction + + + + + + + + + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus. + GO:0048287 + nuclear organisation + nuclear organization + biological_process + nuclear morphology + nuclear organization and biogenesis + nucleus organization and biogenesis + GO:0006997 + + + + + nucleus organization + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus. + GOC:dph + GOC:ems + GOC:jl + GOC:mah + + + + + nuclear organization and biogenesis + GOC:mah + + + + + nucleus organization and biogenesis + GOC:mah + - + - + - + - - + + - + - + - positive regulation of epithelial cell proliferation involved in wound healing + + + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear envelope. + nuclear envelope organisation + biological_process + nuclear envelope organization and biogenesis + GO:0006998 + nuclear envelope organization + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear envelope. + GOC:dph + GOC:ems + GOC:jl + GOC:mah + + + + + nuclear envelope organisation + GOC:mah + + + + + nuclear envelope organization and biogenesis + GOC:mah + - + - + - + - - + + - + - + - angiogenesis involved in wound healing - - - - - - - - - - micturition + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane. + plasma membrane organisation + biological_process + plasma membrane organization and biogenesis + GO:0007009 + + plasma membrane organization + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane. + GOC:dph + GOC:jl + GOC:mah + + + + + plasma membrane organization and biogenesis + GOC:mah + - + - - - eye blink reflex + + + + + + + + + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures. + cytoskeleton organisation + biological_process + cytoskeletal organization and biogenesis + cytoskeletal regulator activity + cytoskeleton organization and biogenesis + GO:0007010 + + + + + + + cytoskeleton organization + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures. + GOC:dph + GOC:jl + GOC:mah + + + + + cytoskeletal organization and biogenesis + GOC:mah + + + + + cytoskeleton organization and biogenesis + GOC:mah + - + - + - + - - + + - - + - smooth muscle contraction involved in micturition - - - - - - - - - molecular transducer activity + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking. + actin filament organisation + regulation of actin filament localization + biological_process + GO:0007015 + actin filament organization + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking. + GOC:mah + - + - + - - - - - + - - + + - - - - - - - - - - - - - - embryonic process involved in female pregnancy + Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins. + https://github.com/geneontology/go-ontology/issues/19809 + biological_process + GO:0007017 + + microtubule-based process + + + + Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins. + GOC:mah + - + - - - - - - - - - - - milk ejection reflex + + + A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules. + biological_process + GO:0007018 + + + microtubule-based movement + + + + A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules. + GOC:cjm + ISBN:0815316194 + - + - - - estrous cycle phase + + + + + + + + + The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules ('de novo' microtubule formation). + Wikipedia:Microtubule_nucleation + biological_process + GO:0007020 + microtubule nucleation + + + + The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules ('de novo' microtubule formation). + GOC:go_curators + ISBN:0815316194 + PMID:12517712 + - + - - - estrus + + + + + + + + + + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cytoplasm. The cytoplasm is all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. + cytoplasm organisation + biological_process + cytoplasm organization and biogenesis + GO:0007028 + + cytoplasm organization + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cytoplasm. The cytoplasm is all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. + GOC:curators + GOC:dph + GOC:jl + GOC:mah + + + + + cytoplasm organization and biogenesis + GOC:mah + - + - + - + - - + + - - - + + - regulation of macromolecule metabolic process + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus. + Golgi organisation + biological_process + Golgi organization and biogenesis + GO:0007030 + + Golgi organization + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus. + GOC:dph + GOC:jl + GOC:mah + + + + + Golgi organization and biogenesis + GOC:mah + - + - + - + - - + + - - - - - - - - regulation of feeding behavior + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole. + GO:0044086 + vacuole organisation + vacuolar assembly + biological_process + vacuole biogenesis + vacuole organization and biogenesis + GO:0007033 + + + + vacuole organization + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole. + GOC:mah + + + + + vacuolar assembly + GOC:mah + + + + + vacuole biogenesis + GOC:mah + + + + + vacuole organization and biogenesis + GOC:mah + - + - + - + - - + + - - - - - - - - regulation of cell development + + The directed movement of substances into, out of or within a vacuole. + biological_process + GO:0007034 + + vacuolar transport + + + + The directed movement of substances into, out of or within a vacuole. + GOC:ai + - + - - - - - - - - - cilium-dependent cell motility + + + + + + + + + + + + + + Any process involved in the maintenance of an internal steady state of calcium ions in the vacuole or between a vacuole and its surroundings. + biological_process + GO:0007036 + vacuolar calcium ion homeostasis + + + + Any process involved in the maintenance of an internal steady state of calcium ions in the vacuole or between a vacuole and its surroundings. + GOC:ai + GOC:mah + - + - + - + - - + + - - - - - - - - cilium movement involved in cell motility + + The chemical reactions and pathways resulting in the breakdown of a protein in the vacuole, usually by the action of vacuolar proteases. + biological_process + vacuolar protein breakdown + vacuolar protein catabolic process + vacuolar protein catabolism + vacuolar protein degradation + GO:0007039 + protein catabolic process in the vacuole + + + + The chemical reactions and pathways resulting in the breakdown of a protein in the vacuole, usually by the action of vacuolar proteases. + GOC:mah + GOC:vw + - + - + - + - - + + - - - - - - - - - regulation of cilium movement involved in cell motility + The aggregation, arrangement and bonding together of a set of components to form a junction between cells. + intercellular junction assembly + biological_process + GO:0007043 + cell-cell junction assembly + + + + The aggregation, arrangement and bonding together of a set of components to form a junction between cells. + GOC:ai + - + - - - - - - - - - bone development + + + The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. + Wikipedia:Cell_cycle + cell-division cycle + biological_process + GO:0007049 + + + + + + + + cell cycle + + + + The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division. + GOC:go_curators + GOC:mtg_cell_cycle + - + - - + + + + + + + + + + + + + + The directed movement of the nucleus to a specific location within a cell. + GO:0040023 + establishment of position of nucleus + nuclear movement + nuclear positioning + nucleus migration + nucleus positioning + positioning of nucleus + biological_process + establishment of cell nucleus localization + establishment of localization of nucleus + establishment of nucleus localisation + establishment of nucleus localization + GO:0007097 + nuclear migration + + + + + The directed movement of the nucleus to a specific location within a cell. + GOC:ai + + + + + establishment of nucleus localisation + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + - - - - + + + + + + + + - - + + + + + + - bone morphogenesis - - - - - - - - - endochondral bone morphogenesis + + + + + + + A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline. + + male nuclear division + biological_process + male meiosis + GO:0007140 + male meiotic nuclear division + + + + A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline. + GOC:dph + GOC:mah + GOC:vw + - + - + - + - + + + + + - + + + + + + + + + + + - - + + + + + + - cartilage development involved in endochondral bone morphogenesis + + + + + + + A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female germline. + + female meiosis + female meiotic division + biological_process + GO:0007143 + Note that female germ lines can be found in female or hermaphroditic organisms, so this term can be used to annotate gene products from hermaphrodites such as those of C. elegans. See also the biological process term 'meiotic nuclear division; GO:0140013'. + female meiotic nuclear division + + + + A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female germline. + GOC:dph + GOC:ems + GOC:mah + GOC:vw + - + - - - flight + + + Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. + Wikipedia:Cell_signaling + biological_process + GO:0007154 + + + cell communication + + + + Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. + GOC:mah + - + - + + + The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules. + dos + 2014-04-15T15:59:10Z + GO:0098602 + Wikipedia:Cell_adhesion + biological_process + cell adhesion molecule activity + single organism cell adhesion + GO:0007155 + + + + + + + + + cell adhesion + + + + + The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules. + GOC:hb + GOC:pf + + + + + + + - + - - + + - - - - - - + + + + + + + + - regulation of penile erection - - - - - - - - + - - + - - + + - + - - - - + - - + + - positive regulation of penile erection + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The attachment of a leukocyte to another cell via adhesion molecules. + + + leukocyte adhesion + leukocyte cell adhesion + biological_process + GO:0007159 + leukocyte cell-cell adhesion + + + + The attachment of a leukocyte to another cell via adhesion molecules. + GOC:go_curators + - + - + - + - - - + + + Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion. + down regulation of cell adhesion + down-regulation of cell adhesion + downregulation of cell adhesion + inhibition of cell adhesion + biological_process + cell adhesion receptor inhibitor activity + GO:0007162 + negative regulation of cell adhesion + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion. + GOC:go_curators + + + + + + + + + Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns. + GO:0030012 + GO:0030467 + biological_process + cell polarity + establishment and/or maintenance of cell polarity + establishment and/or maintenance of cell polarization + GO:0007163 + + + + + establishment or maintenance of cell polarity + + + + + Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns. + GOC:mah + + + + + cell polarity + GOC:mah + GOC:vw + + + + + + + + + - - + + - negative regulation of penile erection + + + + + + + + + + + + + The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. + GO:0023014 + GO:0023015 + GO:0023016 + GO:0023033 + GO:0023045 + Wikipedia:Signal_transduction + signal transduction by cis-phosphorylation + signal transduction by conformational transition + signal transduction by protein phosphorylation + signal transduction by trans-phosphorylation + signaling cascade + signalling cascade + biological_process + signaling pathway + signalling pathway + GO:0007165 + + + + + Note that signal transduction is defined broadly to include a ligand interacting with a receptor, downstream signaling steps and a response being triggered. A change in form of the signal in every step is not necessary. Note that in many cases the end of this process is regulation of the initiation of transcription. Note that specific transcription factors may be annotated to this term, but core/general transcription machinery such as RNA polymerase should not. + signal transduction + + + + The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell. + GOC:go_curators + GOC:mtg_signaling_feb11 + + + + + signalling pathway + GOC:mah + - + - - - epithelium development + + + The series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription. + cell surface receptor linked signal transduction + cell surface receptor linked signaling pathway + cell surface receptor linked signalling pathway + biological_process + GO:0007166 + + cell surface receptor signaling pathway + + + + + The series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription. + GOC:bf + GOC:mah + GOC:pr + GOC:signaling + + + + + cell surface receptor linked signaling pathway + GOC:bf + + + + + cell surface receptor linked signalling pathway + GOC:mah + + + + + + + + + The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell, where the receptor possesses catalytic activity or is closely associated with an enzyme such as a protein kinase, and ending with the regulation of a downstream cellular process, e.g. transcription. + enzyme linked receptor protein signaling pathway + enzyme linked receptor protein signalling pathway + biological_process + GO:0007167 + enzyme-linked receptor protein signaling pathway + + + + + The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell, where the receptor possesses catalytic activity or is closely associated with an enzyme such as a protein kinase, and ending with the regulation of a downstream cellular process, e.g. transcription. + GOC:mah + GOC:signaling + ISBN:0815316194 + + + + + + + + + The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity, and ending with the regulation of a downstream cellular process, e.g. transcription. + transmembrane receptor protein tyrosine kinase signalling pathway + biological_process + GO:0007169 + transmembrane receptor protein tyrosine kinase signaling pathway + + + + + The series of molecular signals initiated by an extracellular ligand binding to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity, and ending with the regulation of a downstream cellular process, e.g. transcription. + GOC:ceb + GOC:signaling + + + + + + + + + + + + + + + + Any process that initiates the activity of the inactive transmembrane receptor protein tyrosine kinase activity. + biological_process + transmembrane receptor protein tyrosine kinase activation + transmembrane receptor protein tyrosine kinase dimerization + GO:0007171 + activation of transmembrane receptor protein tyrosine kinase activity + + + + Any process that initiates the activity of the inactive transmembrane receptor protein tyrosine kinase activity. + GOC:dph + GOC:tb + + + + + transmembrane receptor protein tyrosine kinase activation + GOC:dph + GOC:tb + + + + + transmembrane receptor protein tyrosine kinase dimerization + GOC:dph + GOC:mtg_lung + - + - + - + - - + + + + + + + The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane. + GO:0038042 + G protein coupled receptor protein signaling pathway + G protein coupled receptor protein signalling pathway + G-protein coupled receptor protein signal transduction + G-protein coupled receptor protein signaling pathway + G-protein coupled receptor signalling pathway + G-protein-coupled receptor protein signalling pathway + GPCR signaling pathway + GPCR signalling pathway + G-protein coupled receptor signaling pathway via GPCR dimer + dimeric G-protein coupled receptor signaling pathway + dimeric G-protein coupled receptor signalling pathway + biological_process + GO:0007186 + + G protein-coupled receptor signaling pathway + + + + + The series of molecular signals initiated by a ligand binding to its receptor, in which the activated receptor promotes the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, and ends with regulation of a downstream cellular process. The pathway can start from the plasma membrane, Golgi or nuclear membrane. + GOC:bf + GOC:mah + PMID:16902576 + PMID:24568158 + Wikipedia:G_protein-coupled_receptor + + + + + G-protein coupled receptor protein signaling pathway + GOC:bf + + + + + G-protein coupled receptor signaling pathway via GPCR dimer + GOC:bf + + + + + dimeric G-protein coupled receptor signalling pathway + GOC:mah + + + + + + + + + + + + + + - - - - - + + - positive regulation of cardiac muscle contraction + The series of molecular signals generated as a consequence of a serotonin receptor binding to one of its physiological ligands. + serotonin receptor signalling pathway + biological_process + GO:0007210 + serotonin receptor signaling pathway + + + + The series of molecular signals generated as a consequence of a serotonin receptor binding to one of its physiological ligands. + GOC:mah + - + - + - + - - + + - - - - - - - - - regulation of gastric acid secretion + The series of molecular signals generated by the binding of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, to its receptor on the surface of a target cell. + 4-aminobutanoate signaling pathway + 4-aminobutanoate signalling pathway + 4-aminobutyrate signaling pathway + 4-aminobutyrate signalling pathway + GABA signaling pathway + GABA signalling pathway + gamma-aminobutyric acid signalling pathway + biological_process + GO:0007214 + gamma-aminobutyric acid signaling pathway + + + + The series of molecular signals generated by the binding of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, to its receptor on the surface of a target cell. + GOC:mah + - + - + - + - - + + - - - - - - - - - - positive regulation of gastric acid secretion + + The series of molecular signals initiated by the binding of glutamate to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. + glutamate signaling pathway + glutamate signalling pathway + biological_process + GO:0007215 + glutamate receptor signaling pathway + + + + The series of molecular signals initiated by the binding of glutamate to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription. + GOC:mah + GOC:signaling + PMID:9131252 + + + + + glutamate signaling pathway + GOC:bf + - + - + - + - - + + - - - - - - - - - - negative regulation of gastric acid secretion + + + A G protein-coupled receptor signaling pathway initiated by glutamate binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process. + G-protein coupled glutamate receptor signaling pathway + metabotropic glutamate receptor signaling pathway + metabotropic glutamate receptor signalling pathway + biological_process + GO:0007216 + G protein-coupled glutamate receptor signaling pathway + + + + A G protein-coupled receptor signaling pathway initiated by glutamate binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process. + GOC:mah + GOC:signaling + PMID:9131252 + + + + + metabotropic glutamate receptor signaling pathway + GOC:bf + - + - - + + + - - + - - + + - + - - - + - - + + + + + + - positive regulation of digestive system process + + + + + + + A G protein-coupled receptor signaling pathway initiated by a neuropeptide binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process. + + neuropeptide signalling pathway + biological_process + GO:0007218 + neuropeptide signaling pathway + + + + A G protein-coupled receptor signaling pathway initiated by a neuropeptide binding to its receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process. + GOC:mah + ISBN:0815316194 + - + - - - - - - - - - - - - - - + + + + Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions. + cell-cell signalling + biological_process + GO:0007267 + + + cell-cell signaling + + + + + Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions. + GOC:dos + GOC:mah + + + + + + + + - - + + - negative regulation of digestive system process + + + + + + + + + + + + + The process in which glial cells envelop neuronal cell bodies and/or axons to form an insulating layer. This can take the form of myelinating or non-myelinating ensheathment. + biological_process + ionic insulation of neurons by glial cells + GO:0007272 + ensheathment of neurons + + + + The process in which glial cells envelop neuronal cell bodies and/or axons to form an insulating layer. This can take the form of myelinating or non-myelinating ensheathment. + GOC:dgh + GOC:dph + GOC:tb + - + - + - + - - + + + + + + The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). + https://github.com/geneontology/go-ontology/issues/21234 + biological_process + GO:0007275 + + + + Note that this term was 'developmental process'. + multicellular organism development + + + + + The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). + GOC:dph + GOC:ems + GOC:isa_complete + GOC:tb + + + + + + + - + + + + + + + + + + + - + - positive regulation of flagellated sperm motility involved in capacitation + + + + + + + + + + + + + + + + + The generation and maintenance of gametes in a multicellular organism. A gamete is a haploid reproductive cell. + + GO:0009552 + biological_process + gametogenesis + GO:0007276 + gamete generation + + + + The generation and maintenance of gametes in a multicellular organism. A gamete is a haploid reproductive cell. + GOC:ems + GOC:mtg_sensu + - + - + - + - - + + - + + + - + - developmental growth involved in morphogenesis - - - - - - - - - - epithelial tube morphogenesis + The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism. + germ-cell development + primordial germ cell development + biological_process + GO:0007281 + germ cell development + + + + The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism. + GOC:go_curators + - + - - - tube closure + + + + The developmental process by which male germ line stem cells self renew or give rise to successive cell types resulting in the development of a spermatozoa. + Wikipedia:Spermatogenesis + generation of spermatozoa + biological_process + GO:0007283 + spermatogenesis + + + + The developmental process by which male germ line stem cells self renew or give rise to successive cell types resulting in the development of a spermatozoa. + GOC:jid + ISBN:9780878933846 + PMID:28073824 + PMID:30990821 + + + + + generation of spermatozoa + + - + - + - + - - + + - - - - + + - regulation of vesicle-mediated transport + The mitotic divisions of the primary spermatogonial cell (a primordial male germ cell) to form secondary spermatogonia (primary spermatocytes). + spermatogonium division + biological_process + GO:0007284 + See also the Cell Ontology terms 'spermatogonium ; CL:0000020' and 'primary spermatocyte ; CL:0000656'. + spermatogonial cell division + + + + The mitotic divisions of the primary spermatogonial cell (a primordial male germ cell) to form secondary spermatogonia (primary spermatocytes). + GOC:bf + GOC:pr + ISBN:0879694238 + - + - + - + - - + + - - + - - + + - regulation of microtubule-based movement + The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure. + Wikipedia:Spermiogenesis + spermatid cell development + spermiogenesis + biological_process + GO:0007286 + spermatid development + + + + The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure. + GOC:dph + GOC:go_curators + - + - + - + - - + + - - + + - - + + - regulation of morphogenesis of a branching structure + The assembly and organization of the sperm flagellar axoneme, the bundle of microtubules and associated proteins that forms the core of the eukaryotic sperm flagellum, and is responsible for movement. + biological_process + GO:0007288 + sperm axoneme assembly + + + + The assembly and organization of the sperm flagellar axoneme, the bundle of microtubules and associated proteins that forms the core of the eukaryotic sperm flagellum, and is responsible for movement. + GOC:bf + GOC:cilia + ISBN:0198547684 + - + - - - - - - - - - - - - - - - - - - - - cell-cell signaling involved in mammary gland development + + + Generation of the female gamete; specialised haploid cells produced by meiosis and along with a male gamete takes part in sexual reproduction. + biological_process + GO:0007292 + female gamete generation + + + + Generation of the female gamete; specialised haploid cells produced by meiosis and along with a male gamete takes part in sexual reproduction. + GOC:dph + ISBN:0198506732 + - + - - + + + + - + - endocrine hormone secretion - - - - - - - - - hepaticobiliary system process - - - - - - - - - membrane organization - - - - - - - - - membrane fusion + + + + + + + + + + + + + Construction of a stage-1 egg chamber in the anterior part of the germarium, from the progeny of germ-line and somatic stem cells. An example of this is found in Drosophila melanogaster. + biological_process + GO:0007293 + germarium-derived egg chamber formation + + + + Construction of a stage-1 egg chamber in the anterior part of the germarium, from the progeny of germ-line and somatic stem cells. An example of this is found in Drosophila melanogaster. + GOC:mtg_sensu + ISBN:0879694238 + - + - + - + - - + + - - - + + - regulation of cartilage development + + + + + + + + + + + + + The directed movement of an ovarian follicle cell that takes place during oogenesis. During egg chamber formation, follicle cells migrate to envelop the germ-line cysts and move in between cysts. At stage 10B, follicle cells migrate centripetally between the nurse cells and the oocyte, enclosing the anterior of the egg. An example of this is found in Drosophila melanogaster. + follicle cell migration + biological_process + GO:0007297 + ovarian follicle cell migration + + + + The directed movement of an ovarian follicle cell that takes place during oogenesis. During egg chamber formation, follicle cells migrate to envelop the germ-line cysts and move in between cysts. At stage 10B, follicle cells migrate centripetally between the nurse cells and the oocyte, enclosing the anterior of the egg. An example of this is found in Drosophila melanogaster. + GOC:mtg_sensu + PMID:10822261 + - + - + - + - - + + - - - + - - + + - positive regulation of cartilage development + The construction of a chorion-containing eggshell. An example of this is found in Drosophila melanogaster. + eggshell formation + biological_process + GO:0007304 + chorion-containing eggshell formation + + + + The construction of a chorion-containing eggshell. An example of this is found in Drosophila melanogaster. + GOC:mah + GOC:mtg_sensu + - + - + - + - - + + - - - + + + - - + + - negative regulation of cartilage development + Construction of the vitelline membrane portion of a chorion-containing eggshell. An example of this is found in Drosophila melanogaster. + vitelline membrane formation in chorion-containing eggshell + biological_process + GO:0007305 + vitelline membrane formation involved in chorion-containing eggshell formation + + + + Construction of the vitelline membrane portion of a chorion-containing eggshell. An example of this is found in Drosophila melanogaster. + GOC:mah + GOC:mtg_sensu + + + + + vitelline membrane formation in chorion-containing eggshell + GOC:dph + GOC:tb + - + - + - + - - + + - + + - - + + - regulation of wound healing + The synthesis, deposition, and organization of the materials in a cell of an ovary; where the cell can then undergo meiosis and form an ovum. An example of this is found in Drosophila melanogaster. + GO:0048110 + oocyte arrangement + biological_process + GO:0007308 + oocyte construction + + + + The synthesis, deposition, and organization of the materials in a cell of an ovary; where the cell can then undergo meiosis and form an ovum. An example of this is found in Drosophila melanogaster. + GOC:dph + GOC:ems + GOC:mtg_sensu + GOC:tb + ISBN:0198506732 + + + + + oocyte arrangement + GOC:dph + GOC:tb + - + - + - + - - + + - - - + + - - + + - negative regulation of wound healing + The establishment, maintenance and elaboration of an axis in the oocyte. An example of this is found in Drosophila melanogaster. + GO:0048111 + biological_process + oocyte axis determination + GO:0007309 + oocyte axis specification + + + + The establishment, maintenance and elaboration of an axis in the oocyte. An example of this is found in Drosophila melanogaster. + GOC:mtg_sensu + ISBN:0879694238 + - + - + - + - - + + - + + - - + + + + + Polarization of the oocyte along its anterior-posterior axis. An example of this is found in Drosophila melanogaster. + GO:0048112 + oocyte anterior/posterior axis determination + biological_process + GO:0007314 + oocyte anterior/posterior axis specification + + + + + Polarization of the oocyte along its anterior-posterior axis. An example of this is found in Drosophila melanogaster. + GOC:dph + GOC:mtg_sensu + GOC:tb + ISBN:0879694238 + + + + + oocyte anterior/posterior axis determination + GOC:dph + GOC:tb + + + + + + + + + + + + + + - regulation of nematode larval development + The introduction of semen or sperm into the genital tract of a female. + Wikipedia:Insemination + biological_process + GO:0007320 + insemination + + + + The introduction of semen or sperm into the genital tract of a female. + ISBN:0582227089 + - + - - + + + - - + - - + + - + - - - + - - + + - positive regulation of nematode larval development + + + + + + + + + + + + + + + + + + + + + + + The union of male and female gametes to form a zygote. + + biological_process + zygote biosynthesis + zygote formation + GO:0007338 + single fertilization + + + + The union of male and female gametes to form a zygote. + GOC:ems + GOC:mtg_sensu + - + - + - + - - + + - - + - - + + - negative regulation of nematode larval development + The process in which the egg becomes metabolically active, initiates protein and DNA synthesis and undergoes structural changes to its cortex and/or cytoplasm. + Wikipedia:Egg_activation + biological_process + GO:0007343 + egg activation + + + + The process in which the egg becomes metabolically active, initiates protein and DNA synthesis and undergoes structural changes to its cortex and/or cytoplasm. + GOC:bf + PMID:9630751 + - + - - - - morphogenesis of a branching epithelium + + + + The hierarchical steps resulting in the progressive subdivision of the anterior/posterior axis of the embryo. + biological_process + GO:0007350 + blastoderm segmentation + + + + The hierarchical steps resulting in the progressive subdivision of the anterior/posterior axis of the embryo. + ISBN:0879694238 + http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm + - + - + + + + + + + + + Subdivision of the embryo along the anterior/posterior axis into anterior, posterior and terminal regions. + biological_process + GO:0007351 + tripartite regional subdivision + + + + + Subdivision of the embryo along the anterior/posterior axis into anterior, posterior and terminal regions. + GOC:dph + GOC:isa_complete + ISBN:0879694238 + http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm + + + + + + + - + - - + + - - + + The specification of the anterior/posterior axis of the embryo by products of genes expressed in the zygote; exemplified in insects by the gap genes, pair rule genes and segment polarity gene cascade. + biological_process + GO:0007354 + zygotic determination of anterior/posterior axis, embryo + + + + + The specification of the anterior/posterior axis of the embryo by products of genes expressed in the zygote; exemplified in insects by the gap genes, pair rule genes and segment polarity gene cascade. + ISBN:0879694238 + http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm + + + + + + + + + - - + + - regulation of chondrocyte development + + + + + + + + + + + + + A complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm. + Wikipedia:Gastrulation + biological_process + GO:0007369 + + gastrulation + + + + A complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm. + GOC:curators + ISBN:9780878933846 + - + - + - + - - + + - - - + + - - + + - negative regulation of chondrocyte development + Formation of the amnioserosa, an epithelium that occupies a hole in the embryonic dorsal epidermis. This occurs by the transformation of a narrow strip of cells at the dorsal midline of the blastoderm from columnar to squamous cells, accompanied by a lateral shift. + biological_process + GO:0007378 + amnioserosa formation + + + + Formation of the amnioserosa, an epithelium that occupies a hole in the embryonic dorsal epidermis. This occurs by the transformation of a narrow strip of cells at the dorsal midline of the blastoderm from columnar to squamous cells, accompanied by a lateral shift. + ISBN:0879694238 + - + - - - connective tissue development + + + + + + + + + Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate. + biological_process + pattern biosynthesis + pattern formation + GO:0007389 + + pattern specification process + + + + Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate. + GOC:go_curators + GOC:isa_complete + ISBN:0521436125 + - + - - - reproductive system development + + + + + + + + + + + + + + The process whose specific outcome is the progression of the ectoderm over time, from its formation to the mature structure. In animal embryos, the ectoderm is the outer germ layer of the embryo, formed during gastrulation. + biological_process + GO:0007398 + ectoderm development + + + + The process whose specific outcome is the progression of the ectoderm over time, from its formation to the mature structure. In animal embryos, the ectoderm is the outer germ layer of the embryo, formed during gastrulation. + GOC:dph + GOC:tb + - + - + - + - - + + - - - - - - - - regulation of small molecule metabolic process + + The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state. + biological_process + pan-neural process + GO:0007399 + + nervous system development + + + + The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state. + GOC:dgh + - + - + - + - - + + - - + - - + + - positive regulation of small molecule metabolic process + + + + + + + + + + + + + The expansion of a neuroblast population by cell division. A neuroblast is any cell that will divide and give rise to a neuron. + GO:0043349 + GO:0043350 + biological_process + GO:0007405 + neuroblast proliferation + + + + The expansion of a neuroblast population by cell division. A neuroblast is any cell that will divide and give rise to a neuron. + GOC:ai + GOC:mtg_sensu + GOC:sart + - + - + - + - - - - - - - - - negative regulation of small molecule metabolic process - - - - - - - - - collagen-containing extracellular matrix + + Any process that stops, prevents, or reduces the frequency, rate or extent of the proliferation of neuroblasts. + down regulation of neuroblast proliferation + down-regulation of neuroblast proliferation + downregulation of neuroblast proliferation + suppression of neuroblast proliferation + inhibition of neuroblast proliferation + biological_process + GO:0007406 + negative regulation of neuroblast proliferation + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the proliferation of neuroblasts. + GOC:ai + - + - + - + - - + + - + - + - detection of stimulus involved in sensory perception of pain - - - - - - - - - biological regulation - - - - - - - - - regulation of biological quality + + + + + + + + + + + + + A change in the morphology or behavior of a neuroblast resulting from exposure to an activating factor such as a cellular or soluble ligand. + GO:0043351 + GO:0043352 + biological_process + GO:0007407 + neuroblast activation + + + + A change in the morphology or behavior of a neuroblast resulting from exposure to an activating factor such as a cellular or soluble ligand. + GOC:go_curators + GOC:mtg_sensu + - + - + - + - - + + - + - - + + - regulation of molecular function + + + + + + + De novo generation of a long process of a neuron, including the terminal branched region. Refers to the morphogenesis or creation of shape or form of the developing axon, which carries efferent (outgoing) action potentials from the cell body towards target cells. + GO:0007410 + axon morphogenesis + neuron long process generation + axon growth + biological_process + GO:0007409 + Note that 'axonogenesis' differs from 'axon development' in that the latter also covers other processes, such as axon regeneration (regrowth after loss or damage, not necessarily of the whole axon). + axonogenesis + + + + De novo generation of a long process of a neuron, including the terminal branched region. Refers to the morphogenesis or creation of shape or form of the developing axon, which carries efferent (outgoing) action potentials from the cell body towards target cells. + GOC:dph + GOC:jid + GOC:pg + GOC:pr + ISBN:0198506732 + + + + + axon morphogenesis + GOC:bf + PMID:23517308 + + + + + neuron long process generation + + - + - + - + - - + + - - - extracellular membrane-bounded organelle - - - - - - - - - glucagon secretion + + + + + + + + The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. + Wikipedia:Neural_development + CNS development + biological_process + GO:0007417 + central nervous system development + + + + The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. + GOC:bf + GOC:jid + ISBN:0582227089 + - + - + - + - - + + - + - - + + - regulation of glucagon secretion + The process whose specific outcome is the progression of the ventral midline over time, from its formation to the mature structure. In protostomes (such as insects, snails and worms) as well as deuterostomes (vertebrates), the midline is an embryonic region that functions in patterning of the adjacent nervous tissue. The ventral midline in insects is a cell population extending along the ventral surface of the embryo and is the region from which cells detach to form the ventrally located nerve cords. In vertebrates, the midline is originally located dorsally. During development, it folds inwards and becomes the ventral part of the dorsally located neural tube and is then called the ventral midline, or floor plate. + biological_process + GO:0007418 + ventral midline development + + + + The process whose specific outcome is the progression of the ventral midline over time, from its formation to the mature structure. In protostomes (such as insects, snails and worms) as well as deuterostomes (vertebrates), the midline is an embryonic region that functions in patterning of the adjacent nervous tissue. The ventral midline in insects is a cell population extending along the ventral surface of the embryo and is the region from which cells detach to form the ventrally located nerve cords. In vertebrates, the midline is originally located dorsally. During development, it folds inwards and becomes the ventral part of the dorsally located neural tube and is then called the ventral midline, or floor plate. + GOC:bf + GOC:go_curators + PMID:12075342 + - + - + - + - - + + - - + + - - + + - negative regulation of glucagon secretion + The process whose specific outcome is the progression of the ventral cord over time, from its formation to the mature structure. The ventral cord is one of the distinguishing traits of the central nervous system of all arthropods (such as insects, crustaceans and arachnids) as well as many other invertebrates, such as the annelid worms. + biological_process + GO:0007419 + ventral cord development + + + + The process whose specific outcome is the progression of the ventral cord over time, from its formation to the mature structure. The ventral cord is one of the distinguishing traits of the central nervous system of all arthropods (such as insects, crustaceans and arachnids) as well as many other invertebrates, such as the annelid worms. + GOC:bf + GOC:go_curators + http://users.rcn.com/jkimball.ma.ultranet/BiologyPages/S/Spemann.html + - + - + - + - - + + - - + + - - + + - positive regulation of glucagon secretion + + + + + + + The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.). + biological_process + GO:0007420 + brain development + + + + The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.). + GOC:dph + GOC:jid + GOC:tb + UBERON:0000955 + - + - - - tight junction + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands. + biological_process + GO:0007422 + peripheral nervous system development + + + + The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands. + GOC:go_curators + UBERON:0000010 + - + - - - anchoring junction + + + + + + + + + + + + + + + The process whose specific outcome is the progression of sensory organs over time, from its formation to the mature structure. + sense organ development + biological_process + GO:0007423 + + sensory organ development + + + + The process whose specific outcome is the progression of sensory organs over time, from its formation to the mature structure. + GOC:go_curators + + + + + sense organ development + GOC:dph + - + - + - + - - + + - - + - - + + - regulation of biomineral tissue development + + + + + + + The process whose specific outcome is the progression of an open tracheal system over time, from its formation to the mature structure. An open tracheal system is a respiratory system, a branched network of epithelial tubes that supplies oxygen to target tissues via spiracles. An example of this is found in Drosophila melanogaster. + biological_process + GO:0007424 + See also the fly_anatomy.ontology term 'tracheal system ; FBbt:00005024'. + open tracheal system development + + + + The process whose specific outcome is the progression of an open tracheal system over time, from its formation to the mature structure. An open tracheal system is a respiratory system, a branched network of epithelial tubes that supplies oxygen to target tissues via spiracles. An example of this is found in Drosophila melanogaster. + GOC:mtg_sensu + PMID:8625828 + - + - + - + - - + + - - - - + - - + + - negative regulation of biomineral tissue development + The process whose specific outcome is the progression of the salivary gland over time, from its formation to the mature structure. Salivary glands include any of the saliva-secreting exocrine glands of the oral cavity. + biological_process + GO:0007431 + + salivary gland development + + + + The process whose specific outcome is the progression of the salivary gland over time, from its formation to the mature structure. Salivary glands include any of the saliva-secreting exocrine glands of the oral cavity. + GOC:jid + UBERON:0001044 + - + - + - + - - + + - - - - + - - + + - positive regulation of biomineral tissue development + The process in which the anatomical structures of the salivary gland are generated and organized. + biological_process + GO:0007435 + salivary gland morphogenesis + + + + The process in which the anatomical structures of the salivary gland are generated and organized. + GOC:jid + - + - + - + - - + + - + - - + + - regulation of establishment of protein localization - - - - - - - - - somatostatin secretion + The process whose specific outcome is the progression of the ectodermal digestive tract over time, from its formation to the mature structure. The ectodermal digestive tract includes those portions that are derived from ectoderm. + biological_process + ectodermal gut development + GO:0007439 + ectodermal digestive tract development + + + + The process whose specific outcome is the progression of the ectodermal digestive tract over time, from its formation to the mature structure. The ectodermal digestive tract includes those portions that are derived from ectoderm. + GOC:curators + + + + + ectodermal gut development + GOC:dph + - + - - - - mucus secretion + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the foregut are generated and organized. + biological_process + GO:0007440 + foregut morphogenesis + + + + The process in which the anatomical structures of the foregut are generated and organized. + GOC:jid + - + - + - + - - + + - - - + + - - + + - regulation of mucus secretion + + + + + + + The process in which the anatomical structures of the hindgut are generated and organized. + biological_process + GO:0007442 + hindgut morphogenesis + + + + The process in which the anatomical structures of the hindgut are generated and organized. + GOC:jid + - + - + - + - - + + - - - + + - - + + - negative regulation of mucus secretion + + + + + + + The process in which the anatomical structures of the Malpighian tubule are generated and organized. This process takes place entirely during the embryonic phase. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which leads into the posterior part of the gut. + biological_process + GO:0007443 + See also the fly_anatomy.ontology term 'Malpighian tubule ; FBbt:00005786'. + Malpighian tubule morphogenesis + + + + The process in which the anatomical structures of the Malpighian tubule are generated and organized. This process takes place entirely during the embryonic phase. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which leads into the posterior part of the gut. + GOC:bf + ISBN:0582227089 + - + - + - + - - + + - - - + + - - + + - positive regulation of mucus secretion + + + + + + + The process whose specific outcome is the progression of the imaginal disc over time, from its formation to the metamorphosis to form adult structures. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult structures (legs, antennae, wings, etc.). + biological_process + GO:0007444 + imaginal disc development + + + + The process whose specific outcome is the progression of the imaginal disc over time, from its formation to the metamorphosis to form adult structures. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult structures (legs, antennae, wings, etc.). + GOC:bf + ISBN:0879694238 + - + - - + + + + + + + + + + + + + - + - extracellular matrix constituent secretion - - - - - - - - - renal absorption + The increase in mass of imaginal discs by cell proliferation prior to metamorphosis. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult structures (legs, antennae, wings, etc.) during metamorphosis from larval to adult form. + biological_process + GO:0007446 + imaginal disc growth + + + + The increase in mass of imaginal discs by cell proliferation prior to metamorphosis. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult structures (legs, antennae, wings, etc.) during metamorphosis from larval to adult form. + GOC:bf + GOC:jid + PMID:10679387 + - + - - - - renal water absorption + + + + + + + + + The process in which the anatomical structures derived from the eye-antennal disc are generated and organized. This includes the transformation of an eye-antennal imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the eye, antenna, head capsule and maxillary palps. + eye-antennal disc metamorphosis + biological_process + GO:0007455 + eye-antennal disc morphogenesis + + + + The process in which the anatomical structures derived from the eye-antennal disc are generated and organized. This includes the transformation of an eye-antennal imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the eye, antenna, head capsule and maxillary palps. + GOC:bf + ISBN:0879694238 + - + - - - cell hair + + + + + + + + + The process whose specific outcome is the progression of the antenna over time, from its formation to the mature structure. The antenna are the sensory structures on the head that are capable of detecting various environmental stimuli. + biological_process + GO:0007469 + antennal development + + + + The process whose specific outcome is the progression of the antenna over time, from its formation to the mature structure. The antenna are the sensory structures on the head that are capable of detecting various environmental stimuli. + http://fly.ebi.ac.uk/.bin/cvreport2?id=FBcv0004526 + - + - - - response to oxygen levels + + + + + + + + + The process in which the anatomical structures derived from the wing disc are generated and organized. This includes the transformation of a wing imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the wing hinge, wing blade and pleura. + wing disc metamorphosis + biological_process + GO:0007472 + wing disc morphogenesis + + + + The process in which the anatomical structures derived from the wing disc are generated and organized. This includes the transformation of a wing imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the wing hinge, wing blade and pleura. + GOC:bf + ISBN:0879694238 + - + - - - - detection of hypoxia + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the imaginal disc-derived wing are generated and organized. The wing is an appendage modified for flying. + wing morphogenesis + biological_process + GO:0007476 + imaginal disc-derived wing morphogenesis + + + + The process in which the anatomical structures of the imaginal disc-derived wing are generated and organized. The wing is an appendage modified for flying. + GOC:bf + GOC:mtg_sensu + - + - - - leukocyte proliferation + + + + + + + + + The process in which the anatomical structures derived from the leg disc are generated and organized. This includes the transformation of a leg imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the leg, coxa and ventral thoracic pleura. + leg disc metamorphosis + biological_process + GO:0007478 + leg disc morphogenesis + + + + The process in which the anatomical structures derived from the leg disc are generated and organized. This includes the transformation of a leg imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the leg, coxa and ventral thoracic pleura. + GOC:bf + ISBN:0879694238 + - + - + - + - - + + - + + - - + + - regulation of leukocyte proliferation + + + + + + + + + + + + + The process in which the anatomical structures of a leg derived from an imaginal disc are generated and organized. A leg is a limb on which an animal walks and stands. An example of this is found in Drosophila melanogaster. + biological_process + GO:0007480 + imaginal disc-derived leg morphogenesis + + + + The process in which the anatomical structures of a leg derived from an imaginal disc are generated and organized. A leg is a limb on which an animal walks and stands. An example of this is found in Drosophila melanogaster. + GOC:mtg_sensu + ISBN:0879694238 + - + - + + + + + + + + + The process in which the anatomical structures derived from the haltere disc are generated and organized. This includes the transformation of a haltere imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into the recognizable adult capitellum, pedicel, haltere sclerite, metathoracic spiracle and metanotum. + haltere disc metamorphosis + biological_process + GO:0007481 + haltere disc morphogenesis + + + + + The process in which the anatomical structures derived from the haltere disc are generated and organized. This includes the transformation of a haltere imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into the recognizable adult capitellum, pedicel, haltere sclerite, metathoracic spiracle and metanotum. + GOC:bf + ISBN:0879694238 + + + + + + + - + - - + + - - + - - + + - negative regulation of leukocyte proliferation + The process whose specific outcome is the progression of the haltere over time, from its formation to the mature structure. The haltere is the club-shaped 'balancers' found on each side of the metathorax among the true flies (Diptera). They are the much-modified hind wings. + biological_process + GO:0007482 + haltere development + + + + The process whose specific outcome is the progression of the haltere over time, from its formation to the mature structure. The haltere is the club-shaped 'balancers' found on each side of the metathorax among the true flies (Diptera). They are the much-modified hind wings. + GOC:jid + http://www.earthlife.net + - + - + - + - - + + - - - - - - - - - positive regulation of leukocyte proliferation + + The process whose specific outcome is the progression of the endoderm over time, from its formation to the mature structure. The endoderm is the innermost germ layer that develops into the gastrointestinal tract, the lungs and associated tissues. + biological_process + GO:0007492 + endoderm development + + + + The process whose specific outcome is the progression of the endoderm over time, from its formation to the mature structure. The endoderm is the innermost germ layer that develops into the gastrointestinal tract, the lungs and associated tissues. + GOC:dph + GOC:tb + - + - + - + - - + + - - - - - - - - - - - regulation of bile acid biosynthetic process + + The process whose specific outcome is the progression of the midgut over time, from its formation to the mature structure. The midgut is the middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine. + biological_process + GO:0007494 + midgut development + + + + The process whose specific outcome is the progression of the midgut over time, from its formation to the mature structure. The midgut is the middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine. + GOC:jid + UBERON:0001045 + - + - + - + - - + + - - - - - - - - - - - negative regulation of bile acid biosynthetic process + + The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue. + biological_process + GO:0007498 + + mesoderm development + + + + The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue. + GOC:dph + GOC:tb + - + - + - + - - + + - - - - + + - - + + - positive regulation of bile acid biosynthetic process + + + + + + + The process whose specific outcome is the progression of the fat body over time, from its formation to the mature structure. A fat body is an insect gland dorsal to the insect gut, with a function analogous to that of the vertebrate liver. It is a storage organ for fats, glycogen and protein and is a major site of intermediary metabolism. + biological_process + GO:0007503 + fat body development + + + + The process whose specific outcome is the progression of the fat body over time, from its formation to the mature structure. A fat body is an insect gland dorsal to the insect gut, with a function analogous to that of the vertebrate liver. It is a storage organ for fats, glycogen and protein and is a major site of intermediary metabolism. + ISBN:0582227089 + - + - + - + - - + + - - - + + - - + + - regulation of glycogen metabolic process + The process whose specific outcome is the progression of the gonadal mesoderm over time, from its formation to the mature structure. The gonadal mesoderm is the middle layer of the three primary germ layers of the embryo which will go on to form the gonads of the organism. + biological_process + GO:0007506 + gonadal mesoderm development + + + + The process whose specific outcome is the progression of the gonadal mesoderm over time, from its formation to the mature structure. The gonadal mesoderm is the middle layer of the three primary germ layers of the embryo which will go on to form the gonads of the organism. + GOC:ai + - + - + - + - - + + - - - + + - - + + - negative regulation of glycogen metabolic process + The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. + GO:0007511 + Wikipedia:Heart_development + dorsal vessel development + biological_process + cardiac development + GO:0007507 + heart development + + + + The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. + GOC:jid + UBERON:0000948 + - + - + - + - - + + - - - + - - + + - positive regulation of glycogen metabolic process - - - - - - - - - - cellular response to chemical stimulus - - - - - - - - - vocalization behavior - - - - - - - - - mastication - - - - - - - - - organism emergence from protective structure - - - - - - - - - protein localization to extracellular region - - - - - - - - - - + + - anatomical structure maturation - - - - - - - - - organic substance transport - - - - - - - - - organic substance metabolic process - - - - - - - - - nitrogen compound transport - - - - - - - - - mating pheromone secretion - - - - - - - - - cellular component organization or biogenesis - - - - - - - - - cell periphery - - - - - - - - - - + + - elastic fiber + The process whose specific outcome is the progression of the hemocyte over time, from its formation to the mature structure. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. + arthropod blood cell development + biological_process + GO:0007516 + hemocyte development + + + + The process whose specific outcome is the progression of the hemocyte over time, from its formation to the mature structure. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. + GOC:bf + GOC:mtg_sensu + - + - - - - - - - - - epithelial tube formation + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work. + biological_process + GO:0007517 + muscle organ development + + + + The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work. + GOC:jid + ISBN:0198506732 + - + - + - + - - + + - - - - + + - negative regulation of mesenchymal cell proliferation + The developmental sequence of events leading to the formation of adult skeletal muscle tissue. The main events are: the fusion of myoblasts to form myotubes that increase in size by further fusion to them of myoblasts, the formation of myofibrils within their cytoplasm and the establishment of functional neuromuscular junctions with motor neurons. At this stage they can be regarded as mature muscle fibers. + GO:0048637 + biological_process + myogenesis + GO:0007519 + skeletal muscle tissue development + + + + The developmental sequence of events leading to the formation of adult skeletal muscle tissue. The main events are: the fusion of myoblasts to form myotubes that increase in size by further fusion to them of myoblasts, the formation of myofibrils within their cytoplasm and the establishment of functional neuromuscular junctions with motor neurons. At this stage they can be regarded as mature muscle fibers. + GOC:mtg_muscle + - + - - - - monocarboxylic acid biosynthetic process + + + + + + + + + + + + + + The process whose specific outcome is the progression of the somatic muscle over time, from its formation to the mature structure. Somatic muscles are striated muscle structures that connect to the exoskeleton or cuticle. + biological_process + GO:0007525 + somatic muscle development + + + + The process whose specific outcome is the progression of the somatic muscle over time, from its formation to the mature structure. Somatic muscles are striated muscle structures that connect to the exoskeleton or cuticle. + GOC:jid + GOC:mtg_muscle + - + - - - circulatory system development + + + The establishment of the sex of an organism by physical differentiation. + Wikipedia:Sexual_differentiation + biological_process + GO:0007548 + sex differentiation + + + + The establishment of the sex of an organism by physical differentiation. + GOC:ai + - + - - - - divalent inorganic cation homeostasis + + + + A biological process in which an animal physically develops after birth or hatching, involving a conspicuous and relatively abrupt change in the animal's form or structure. Examples include the change from tadpole to frog, and the change from larva to adult. An example of this is found in Drosophila melanogaster. + GO:0046698 + GO:0046699 + Wikipedia:Metamorphosis + biological_process + GO:0007552 + metamorphosis + + + + A biological process in which an animal physically develops after birth or hatching, involving a conspicuous and relatively abrupt change in the animal's form or structure. Examples include the change from tadpole to frog, and the change from larva to adult. An example of this is found in Drosophila melanogaster. + GOC:sensu + ISBN:0198506732 + ISBN:0721662544 + - + - + - + - + + + + + + + - + - regulation of primary metabolic process + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone. + regulation of juvenile hormone metabolism + biological_process + GO:0007556 + regulation of juvenile hormone metabolic process + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone. + GOC:go_curators + - + - + - + - - - - - - - - regulation of response to stress + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone. + regulation of juvenile hormone anabolism + regulation of juvenile hormone biosynthesis + regulation of juvenile hormone formation + regulation of juvenile hormone synthesis + biological_process + GO:0007557 + regulation of juvenile hormone biosynthetic process + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone. + GOC:go_curators + - + - - - - regulation of steroid hormone biosynthetic process - - - - - - - - - - - positive regulation of steroid hormone biosynthetic process - - - - - - - - - - - negative regulation of steroid hormone biosynthetic process - - - - - - - + - - + + - - - - + + - positive regulation of cell cycle process + Any process that modulates the frequency, rate or extent of juvenile hormone secretion. + biological_process + GO:0007558 + regulation of juvenile hormone secretion + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate or extent of juvenile hormone secretion. + GOC:go_curators + - + - + - + - - + + - + - - + + - regulation of peptide transport - - - - - - - - - - organelle membrane fusion + + + + + + + + + + + + + The process in which the anatomical structures derived from an imaginal disc are generated and organized. The imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult appendages (legs, antennae, wings, etc.) during metamorphosis from larval to adult form. + GO:0007452 + imaginal disc metamorphosis + biological_process + GO:0007560 + imaginal disc morphogenesis + + + + The process in which the anatomical structures derived from an imaginal disc are generated and organized. The imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult appendages (legs, antennae, wings, etc.) during metamorphosis from larval to adult form. + GOC:jid + - + - - - - - - - - - - - - - + + - - + + - regulation of muscle system process + The emergence of an adult insect from a pupa case. + Wikipedia:Pupa#Emergence + biological_process + GO:0007562 + eclosion + + + + The emergence of an adult insect from a pupa case. + GOC:dgh + GOC:dos + GOC:mah + ISBN:0198600461 + - + - + - + - - + - regulation of somatostatin secretion + Any process that modulates the frequency, rate or extent of the emergence of an insect from a pupa-case or of a larva from an egg. + biological_process + GO:0007563 + regulation of eclosion + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate or extent of the emergence of an insect from a pupa-case or of a larva from an egg. + GOC:go_curators + ISBN:0198600461 + - + - - - - - - - - - - - - - - + + + - - + + - positive regulation of somatostatin secretion - - - - - - - - - - - - - - - - - - - - - - + + - negative regulation of somatostatin secretion + The set of physiological processes that allow an embryo or foetus to develop within the body of a female animal. It covers the time from fertilization of a female ovum by a male spermatozoon until birth. + Wikipedia:Gestation + gestation + biological_process + carrying of young + GO:0007565 + + female pregnancy + + + + The set of physiological processes that allow an embryo or foetus to develop within the body of a female animal. It covers the time from fertilization of a female ovum by a male spermatozoon until birth. + ISBN:0192800825 + - + - - - - - - - - - - - - - - + + - - + + - regulation of peptide hormone secretion + + + + + + + Attachment of the blastocyst to the uterine lining. + blastocyst implantation + biological_process + GO:0007566 + embryo implantation + + + + Attachment of the blastocyst to the uterine lining. + GOC:isa_complete + http://www.medterms.com + - + - - - - - - - - - - - - - - - - - - - - - - positive regulation of peptide hormone secretion + + + The process of gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms. + breathing + respiration + biological_process + GO:0007585 + + respiratory gaseous exchange by respiratory system + + + + The process of gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms. + ISBN:0198506732 + - + - - - - - - - - - - - - - - - - - - - - - - negative regulation of peptide hormone secretion + + + The whole of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. + Wikipedia:Digestion + biological_process + GO:0007586 + + + digestion + + + + The whole of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. + GOC:isa_complete + ISBN:0198506732 + - + - - - - - - - - - - - - - - - - - - - - - positive regulation of wound healing + + + The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds. + https://github.com/geneontology/go-ontology/issues/22368 + Wikipedia:Excretion + biological_process + GO:0007588 + + + excretion + + + + The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds. + ISBN:0192801023 + - + - - - - - - - - - - - - - - - - - - - - - regulation of locomotion involved in locomotory behavior + + + + The controlled release of a fluid by a cell or tissue in an animal. + biological_process + GO:0007589 + body fluid secretion + + + + The controlled release of a fluid by a cell or tissue in an animal. + GOC:ai + GOC:dph + GOC:mah + GOC:tb + - + - - - - - - - - - - - - - - - + + - - + + - positive regulation of locomotion involved in locomotory behavior + + + + + + + The periodic shedding of part or all of a chitin-based cuticle, which is then replaced by a new cuticle. An example of this is found in Drosophila melanogaster. + chitin-based cuticle molting cycle + biological_process + GO:0007591 + molting cycle, chitin-based cuticle + + + + The periodic shedding of part or all of a chitin-based cuticle, which is then replaced by a new cuticle. An example of this is found in Drosophila melanogaster. + GOC:jl + GOC:mtg_sensu + + + + + chitin-based cuticle molting cycle + GOC:dph + GOC:tb + - + - - - - - - - - - - - - - - - + + - - + + - negative regulation of locomotion involved in locomotory behavior + + + + + + + + + + + + + + + + + + + The regulated release of milk from the mammary glands and the period of time that a mother lactates to feed her young. + Wikipedia:Lactation + milk secretion + biological_process + GO:0007595 + lactation + + + + The regulated release of milk from the mammary glands and the period of time that a mother lactates to feed her young. + ISBN:0198506732 + + + + + milk secretion + GOC:pr + - + - + - + - - + + - - - + + - - + + - regulation of olfactory learning - - - - - - - - - - inflammatory response to wounding + The sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers. + Wikipedia:Coagulation + blood clotting + biological_process + GO:0007596 + blood coagulation + + + + The sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers. + ISBN:0198506732 + http://www.graylab.ac.uk/omd/ + - + - - - - - - - - - immunological memory process + + + The stopping of bleeding (loss of body fluid) or the arrest of the circulation to an organ or part. + Wikipedia:Hemostasis + biological_process + GO:0007599 + hemostasis + + + + The stopping of bleeding (loss of body fluid) or the arrest of the circulation to an organ or part. + ISBN:0198506732 + - + - - - immunological memory formation process + + + The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. + Wikipedia:Perception + biological_process + GO:0007600 + + sensory perception + + + + The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. + GOC:ai + GOC:dph + - + - - - - - - - - - - - - - - - - - - - - ciliary plasm + + + The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image. + Wikipedia:Visual_perception + sense of sight + sensory visual perception + vision + biological_process + GO:0007601 + visual perception + + + + The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image. + GOC:ai + - + - - - ammonium ion metabolic process + + + The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound. + Wikipedia:Hearing_(sense) + hearing + perception of sound + biological_process + GO:0007605 + sensory perception of sound + + + + The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound. + GOC:ai + - + - - - renal filtration + + + The series of events required for an organism to receive a sensory chemical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. + chemosensory perception + biological_process + GO:0007606 + sensory perception of chemical stimulus + + + + The series of events required for an organism to receive a sensory chemical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. + GOC:ai + - + - - - glial cell projection + + + The series of events required for an organism to receive an olfactory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Olfaction involves the detection of chemical composition of an organism's ambient medium by chemoreceptors. This is a neurological process. + Wikipedia:Olfaction + olfaction + scent perception + sense of smell + smell perception + biological_process + GO:0007608 + sensory perception of smell + + + + The series of events required for an organism to receive an olfactory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Olfaction involves the detection of chemical composition of an organism's ambient medium by chemoreceptors. This is a neurological process. + GOC:ai + - + - - + + - - + + - - + + - dendritic tree + + + + + + + + The internally coordinated responses (actions or inactions) of animals (individuals or groups) to internal or external stimuli, via a mechanism that involves nervous system activity. + jl + 2012-09-20T14:06:08Z + GO:0023032 + GO:0044708 + GO:0044709 + Wikipedia:Behavior + behavioral response to stimulus + behaviour + behavioural response to stimulus + biological_process + single-organism behavior + GO:0007610 + + + + 1. Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation reviews. +2. While a broader definition of behavior encompassing plants and single cell organisms would be justified on the basis of some usage (see PMID:20160973 for discussion), GO uses a tight definition that limits behavior to animals and to responses involving the nervous system, excluding plant responses that GO classifies under development, and responses of unicellular organisms that has general classifications for covering the responses of cells in multicellular organisms (e.g. cell chemotaxis). + behavior + + + + The internally coordinated responses (actions or inactions) of animals (individuals or groups) to internal or external stimuli, via a mechanism that involves nervous system activity. + GOC:ems + GOC:jl + ISBN:0395448956 + PMID:20160973 + - + - - - astrocyte projection + + + + + The acquisition and processing of information and/or the storage and retrieval of this information over time. + biological_process + GO:0007611 + learning or memory + + + + The acquisition and processing of information and/or the storage and retrieval of this information over time. + GOC:jid + PMID:8938125 + - + - - - astrocyte end-foot + + + Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience. + Wikipedia:Learning + biological_process + GO:0007612 + learning + + + + Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience. + ISBN:0582227089 + ISBN:0721662544 + - + - - - hippocampal mossy fiber + + + The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task). + Wikipedia:Memory + biological_process + GO:0007613 + memory + + + + The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task). + GOC:curators + ISBN:0582227089 + - + - - - - - - - - - - - - - - - intracellular vesicle + + + The behavioral interactions between organisms for the purpose of mating, or sexual reproduction resulting in the formation of zygotes. + Wikipedia:Mating_behaviour + mating behaviour + biological_process + GO:0007617 + mating behavior + + + + The behavioral interactions between organisms for the purpose of mating, or sexual reproduction resulting in the formation of zygotes. + GOC:ai + GOC:dph + - + - - - - sperm motility + + + The act of sexual union between male and female, involving the transfer of sperm. + biological_process + GO:0007620 + copulation + + + + The act of sexual union between male and female, involving the transfer of sperm. + ISBN:0721662544 + - + - - - non-motile cilium - - + + + The specific behavior of an organism that recur with measured regularity. + rhythmic behavioral response to stimulus + rhythmic behaviour + rhythmic behavioural response to stimulus + biological_process + GO:0007622 + rhythmic behavior + + + + + The specific behavior of an organism that recur with measured regularity. + GOC:jl + GOC:pr + + - + - - - 9+0 non-motile cilium + + + Any biological process in an organism that recurs with a regularity of approximately 24 hours. + GO:0050895 + Wikipedia:Circadian_rhythm + circadian process + biological_process + circadian response + response to circadian rhythm + GO:0007623 + + + circadian rhythm + + + + Any biological process in an organism that recurs with a regularity of approximately 24 hours. + GOC:bf + GOC:go_curators + - + - - - - photoreceptor cell cilium + + + The specific behavior of an organism relating to grooming, cleaning and brushing to remove dirt and parasites. + grooming behaviour + biological_process + GO:0007625 + grooming behavior + + + + The specific behavior of an organism relating to grooming, cleaning and brushing to remove dirt and parasites. + GOC:jl + GOC:pr + - + - - - - learned vocalization behavior + + + The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions. + behavior via locomotion + locomotion in response to stimulus + locomotory behavioral response to stimulus + locomotory behaviour + locomotory behavioural response to stimulus + biological_process + GO:0007626 + + locomotory behavior + + + + The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions. + GOC:dph + - + - - - - - - - - - - - - - - - - - - - - plasma membrane region + + + Behavior associated with the intake of food. + https://github.com/geneontology/go-ontology/issues/18547 + jl + 2011-10-27T03:53:33Z + GO:0044366 + GO:0044367 + GO:0044368 + GO:0044369 + GO:0044370 + GO:0044371 + GO:0044372 + Wikipedia:List_of_feeding_behaviours + behavioral response to food + behavioural response to food + feeding behaviour + eating + feeding from phloem of other organism + feeding from plant phloem + feeding from tissue of other organism + feeding from vascular tissue of another organism + feeding from xylem of other organism + feeding on blood of other organism + feeding on or from other organism + feeding on plant sap + hematophagy + injection of substance into other organism during feeding on blood of other organism + taking of blood meal + biological_process + GO:0007631 + See also the biological process term 'behavior ; GO:0007610'. + feeding behavior + + + + Behavior associated with the intake of food. + GOC:mah + - + - - - learned vocalization behavior or vocal learning + + + + + + + + + Behavior that is dependent upon the sensation of chemicals. + behavioral response to chemical stimulus + behavioural response to chemical stimulus + chemosensory behaviour + biological_process + GO:0007635 + chemosensory behavior + + + + Behavior that is dependent upon the sensation of chemicals. + GOC:go_curators + - + - - - cell-cell adhesion + + + The flow of blood through the body of an animal, enabling the transport of nutrients to the tissues and the removal of waste products. + GO:0070261 + biological_process + hemolymph circulation + GO:0008015 + + blood circulation + + + + The flow of blood through the body of an animal, enabling the transport of nutrients to the tissues and the removal of waste products. + GOC:mtg_heart + ISBN:0192800825 + - + - + - + - - + + - - - - - - - - network-forming collagen trimer - - - - - - - - - - banded collagen fibril - - - - - - - - - - - - - - - - - - - - - complex of collagen trimers - - - - - - - - - - collagen network + + Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process in which the heart decreases in volume in a characteristic way to propel blood through the body. + regulation of cardiac contraction + biological_process + GO:0008016 + regulation of heart contraction + + + + Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process in which the heart decreases in volume in a characteristic way to propel blood through the body. + GOC:dph + GOC:go_curators + GOC:tb + - + - + - + - - + + - - - - - - - - basement membrane collagen trimer + + Binding to a microtubule, a filament composed of tubulin monomers. + Reactome:R-HSA-9614343 + molecular_function + microtubule severing activity + microtubule/chromatin interaction + GO:0008017 + microtubule binding + + + + Binding to a microtubule, a filament composed of tubulin monomers. + GOC:krc + + + + + Reactome:R-HSA-9614343 + Viral UL47:UL48 Proteins Bind HCMV Tegumented Virion to Host Microtuble and Dynein complexs + - + - - - inorganic ion homeostasis + + + + + + + + + + + + + Binds to and increases the activity of an enzyme. + GO:0010577 + metalloenzyme activator activity + molecular_function + GO:0008047 + This term should only be used in cases when the regulator directly interacts with the enzyme. + enzyme activator activity + + + + Binds to and increases the activity of an enzyme. + GOC:dph + GOC:mah + GOC:tb + - + - + - + - - + + - + + - + - membrane protein complex + The process whose specific outcome is the progression of the ocellus over time, from its formation to the mature structure. The ocellus is a simple visual organ of insects. + biological_process + GO:0008056 + ocellus development + + + + The process whose specific outcome is the progression of the ocellus over time, from its formation to the mature structure. The ocellus is a simple visual organ of insects. + http://fly.ebi.ac.uk/.bin/cvreport2?id=FBcv0004540 + - + - + - + - - + + - - - - - - - - plasma membrane protein complex + + Binding to chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues. + molecular_function + GO:0008061 + + chitin binding + + + + Binding to chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues. + GOC:jl + ISBN:0198506732 + - + - + - + - - + + - + - - + + - regulation of renal system process + Combining with glutamate and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. + molecular_function + GO:0008066 + glutamate receptor activity + + + + Combining with glutamate and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. + GOC:ai + GOC:signaling + - + - - - podocyte foot + + + + + + + + + + + + + + The orderly movement of mesodermal cells from one site to another. + mesoderm cell migration + biological_process + GO:0008078 + mesodermal cell migration + + + + The orderly movement of mesodermal cells from one site to another. + GOC:ascb_2009 + GOC:dph + GOC:mah + GOC:sat + GOC:tb + PMID:25119047 + - + - - - - - - - - - actin-based cell projection + + + + + + + + + + + + + + + + + + The directed movement of organelles or molecules along microtubules in neuron projections. + Wikipedia:Axoplasmic_transport + axon cargo transport + axonal transport + axoplasmic transport + biological_process + GO:0008088 + + axo-dendritic transport + + + + The directed movement of organelles or molecules along microtubules in neuron projections. + ISBN:0815316194 + - + - - - supramolecular complex + + + Binding to a protein component of a cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton). + molecular_function + GO:0008092 + + + + + + + + + cytoskeletal protein binding + + + + Binding to a protein component of a cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton). + GOC:mah + - + - - - supramolecular polymer + + + + + + + + + + + + + + + Any process in which a protein is transported to, or maintained in, a specific location. + https://github.com/geneontology/go-ontology/issues/23112 + GO:0008105 + GO:0016249 + GO:0034613 + cellular protein localisation + cellular protein localization + protein localisation + channel localizer activity + biological_process + asymmetric protein localisation + asymmetric protein localization + establishment and maintenance of asymmetric protein localization + establishment and maintenance of protein localization + GO:0008104 + + protein localization + + + + Any process in which a protein is transported to, or maintained in, a specific location. + GOC:ai + + + + + cellular protein localisation + GOC:mah + + + + + protein localisation + GOC:mah + + + + + channel localizer activity + GOC:mah + + + + + asymmetric protein localisation + GOC:mah + - + - - - - vesicle fusion to plasma membrane + + + A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence. + jl + 2012-09-19T15:05:24Z + GO:0000004 + GO:0007582 + GO:0044699 + Wikipedia:Biological_process + biological process + physiological process + biological_process + single organism process + single-organism process + GO:0008150 + + + + + + + + Note that, in addition to forming the root of the biological process ontology, this term is recommended for use for the annotation of gene products whose biological process is unknown. When this term is used for annotation, it indicates that no information was available about the biological process of the gene product annotated as of the date the annotation was made; the evidence code 'no data' (ND), is used to indicate this. + biological_process + + + + A biological process represents a specific objective that the organism is genetically programmed to achieve. Biological processes are often described by their outcome or ending state, e.g., the biological process of cell division results in the creation of two daughter cells (a divided cell) from a single parent cell. A biological process is accomplished by a particular set of molecular functions carried out by specific gene products (or macromolecular complexes), often in a highly regulated manner and in a particular temporal sequence. + GOC:pdt + - + - - - supramolecular fiber + + + + + The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation. + jl + 2012-10-17T15:46:40Z + GO:0044236 + GO:0044710 + Wikipedia:Metabolism + metabolism + metabolic process resulting in cell growth + metabolism resulting in cell growth + multicellular organism metabolic process + biological_process + single-organism metabolic process + GO:0008152 + + + + + + Note that metabolic processes do not include single functions or processes such as protein-protein interactions, protein-nucleic acids, nor receptor-ligand interactions. + metabolic process + + + + The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation. + GOC:go_curators + ISBN:0198547684 + - + - - + + + + + + + + + + + + + - + - polymeric cytoskeletal fiber + + + + + + + + + + + + + + + + + + + + + + + Combining with a neuropeptide to initiate a change in cell activity. + + molecular_function + GO:0008188 + neuropeptide receptor activity + + + + Combining with a neuropeptide to initiate a change in cell activity. + GOC:ai + - + - + - + - - + + - - - - - - - - cytoplasmic region + + + The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. + Wikipedia:Steroid_metabolism + steroid metabolism + biological_process + GO:0008202 + steroid metabolic process + + + + The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. + ISBN:0198547684 + - + - + - + - - + + - - - - - - - - - cell cortex region + + + + The chemical reactions and pathways involving bile acids, a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine. + bile acid metabolism + biological_process + GO:0008206 + bile acid metabolic process + + + + The chemical reactions and pathways involving bile acids, a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine. + GOC:go_curators + - + - + - + - - + + - - - - - - - - - regulation of inflammatory response to wounding + + + + The chemical reactions and pathways involving C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones. + C21-steroid hormone metabolism + biological_process + GO:0008207 + C21-steroid hormone metabolic process + + + + The chemical reactions and pathways involving C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones. + GOC:ai + - + - + - + - - + + - - - - - - - - - - negative regulation of inflammatory response to wounding + + The chemical reactions and pathways resulting in the breakdown of C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones. + C21-steroid hormone breakdown + C21-steroid hormone catabolism + C21-steroid hormone degradation + biological_process + GO:0008208 + C21-steroid hormone catabolic process + + + + The chemical reactions and pathways resulting in the breakdown of C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones. + GOC:ai + - + - + - + - - + + - - - - - - - - - - positive regulation of inflammatory response to wounding + + The chemical reactions and pathways involving glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects. + glucocorticoid metabolism + glucocorticosteroid metabolic process + glucocorticosteroid metabolism + biological_process + GO:0008211 + glucocorticoid metabolic process + + + + The chemical reactions and pathways involving glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects. + ISBN:0198506732 + - + - + - + - - + + - - - + + + + The chemical reactions and pathways involving mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. Mineralocorticoids act primarily on water and electrolyte balance. + mineralocorticoid metabolism + biological_process + GO:0008212 + mineralocorticoid metabolic process + + + + + The chemical reactions and pathways involving mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. Mineralocorticoids act primarily on water and electrolyte balance. + ISBN:0198506732 + + + + + + + + - - + + - positive regulation of animal organ morphogenesis + Any process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure. + Wikipedia:Blood_pressure#Regulation + blood pressure regulation + biological_process + blood pressure homeostasis + control of blood pressure + GO:0008217 + regulation of blood pressure + + + + Any process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure. + GOC:dph + GOC:mtg_cardio + ISBN:0721643949 + - + - + - + - - + + - - - - - - - - - - negative regulation of animal organ morphogenesis - - - - - - - - - biomineralization + Combining with an extracellular amine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. + G-protein coupled amine receptor activity + amine receptor activity, G-protein coupled + biogenic amine receptor + molecular_function + GO:0008227 + G protein-coupled amine receptor activity + + + + Combining with an extracellular amine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. + GOC:bf + GOC:dph + + + + + amine receptor activity, G-protein coupled + GOC:bf + - + - + - + - - - - - - - - regulation of biomineralization + Any process that modulates the frequency, rate or extent of G protein-coupled receptor signaling pathway. + regulation of G protein coupled receptor protein signaling pathway + regulation of G protein coupled receptor protein signalling pathway + regulation of G-protein coupled receptor protein signaling pathway + regulation of G-protein coupled receptor protein signalling pathway + regulation of G-protein-coupled receptor protein signalling pathway + regulation of GPCR protein signaling pathway + regulation of GPCR protein signalling pathway + biological_process + GO:0008277 + regulation of G protein-coupled receptor signaling pathway + + + + Any process that modulates the frequency, rate or extent of G protein-coupled receptor signaling pathway. + GOC:go_curators + - + - - + + + - - + - - + + - + - - - + - - + + + + + + - negative regulation of biomineralization + + + + + + + The multiplication or reproduction of cells, resulting in the expansion of a cell population. + + biological_process + cell proliferation + GO:0008283 + + + + + + + This term was moved out from being a child of 'cellular process' because it is a cell population-level process, and cellular processes are restricted to those processes that involve individual cells. Also note that this term is intended to be used for the proliferation of cells within a multicellular organism, not for the expansion of a population of single-celled organisms. + cell population proliferation + + + + The multiplication or reproduction of cells, resulting in the expansion of a cell population. + GOC:mah + GOC:mb + - + - + - + - - + + + + + + + + + + + + - - + + + + + + - positive regulation of biomineralization - - - - - - - - - cellular anatomical entity + + + + + + + Any process that activates or increases the rate or extent of cell proliferation. + + up regulation of cell proliferation + up-regulation of cell proliferation + upregulation of cell proliferation + activation of cell proliferation + stimulation of cell proliferation + biological_process + positive regulation of cell proliferation + GO:0008284 + positive regulation of cell population proliferation + + + + Any process that activates or increases the rate or extent of cell proliferation. + GOC:go_curators + - + - + - + - - + + - + + + + + + + + + + + + - - + + + + + + - plasma membrane bounded cell projection - + + + + + + + Any process that stops, prevents or reduces the rate or extent of cell proliferation. + + down regulation of cell proliferation + down-regulation of cell proliferation + downregulation of cell proliferation + inhibition of cell proliferation + biological_process + negative regulation of cell proliferation + GO:0008285 + negative regulation of cell population proliferation + + + + + Any process that stops, prevents or reduces the rate or extent of cell proliferation. + GOC:go_curators + - + - - - - - - - - - - - - - + + - + - neuron projection cytoplasm - - - - - - - - - - steroid hormone biosynthetic process + + + + + + + + + + + + + The series of molecular signals generated as a consequence of the insulin receptor binding to insulin. + insulin receptor signalling pathway + daf-2 receptor signaling pathway + biological_process + GO:0008286 + insulin receptor signaling pathway + + + + The series of molecular signals generated as a consequence of the insulin receptor binding to insulin. + GOC:ceb + - + - - - olefinic compound metabolic process + + + + + + + + + + + + + Binding to a lipid. + molecular_function + GO:0008289 + + + + + + + + + + + + lipid binding + + + + Binding to a lipid. + GOC:ai + - + - - - - olefinic compound biosynthetic process + + + Learning by associating a stimulus (the cause) with a particular outcome (the effect). + Wikipedia:Learning#Associative_learning + Pavlovian conditioning + classical conditioning + conditional learning + conditional response + biological_process + GO:0008306 + associative learning + + + + Learning by associating a stimulus (the cause) with a particular outcome (the effect). + ISBN:0582227089 + - + - + - + - - + + - - - meiotic nuclear division + + + + + + + + + + + + + + + + + + + + The orderly movement of a glial cell, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system. + GO:0043359 + glia cell migration + biological_process + GO:0008347 + glial cell migration + + + + The orderly movement of a glial cell, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system. + GOC:jl + GOC:mtg_sensu + - + - + - + - - + + - + - + - exocytic process + The orderly movement of a cell specialized to produce haploid gametes through the embryo from its site of production to the place where the gonads will form. + germ-cell migration + biological_process + primordial germ cell migration + GO:0008354 + germ cell migration + + + + The orderly movement of a cell specialized to produce haploid gametes through the embryo from its site of production to the place where the gonads will form. + GOC:bf + GOC:jl + - + - - - - export from cell + + + + Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue. + biological_process + GO:0008355 + olfactory learning + + + + Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue. + ISBN:0582227089 + - + - - - - lipid export from cell + + + The asymmetric division of cells to produce two daughter cells with different developmental potentials. It is of fundamental significance for the generation of cell diversity. + Wikipedia:Asymmetric_cell_division + asymmetrical cell division + biological_process + asymmetric cytokinesis + asymmetrical cytokinesis + GO:0008356 + asymmetric cell division + + + + The asymmetric division of cells to produce two daughter cells with different developmental potentials. It is of fundamental significance for the generation of cell diversity. + PMID:11672519 + - + - - - - - - - - - - - - - + + + The specification of the anterior/posterior axis of the embryo by gradients of maternally-transcribed gene products; exemplified in insects by the morphogens, bicoid and nanos. + biological_process + GO:0008358 + maternal determination of anterior/posterior axis, embryo + + + + + The specification of the anterior/posterior axis of the embryo by gradients of maternally-transcribed gene products; exemplified in insects by the morphogens, bicoid and nanos. + ISBN:0879694238 + http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm + + + + + + + + - - + + - nuclear protein-containing complex + Any process in which the axon of a neuron is insulated, and that insulation maintained, thereby preventing dispersion of the electrical signal. + GO:0042553 + cellular axon ensheathment + biological_process + cellular nerve ensheathment + nerve ensheathment + GO:0008366 + axon ensheathment + + + + Any process in which the axon of a neuron is insulated, and that insulation maintained, thereby preventing dispersion of the electrical signal. + GOC:jl + ISBN:0878932437 + - + - + - + - - + + - - + + + + - - + + - regulation of hemostasis + The process whose specific outcome is the progression of the gonad over time, from its formation to the mature structure. The gonad is an animal organ that produces gametes; in some species it also produces hormones. + gonadogenesis + biological_process + GO:0008406 + gonad development + + + + The process whose specific outcome is the progression of the gonad over time, from its formation to the mature structure. The gonad is an animal organ that produces gametes; in some species it also produces hormones. + GOC:ems + ISBN:0198506732 + + + + + gonadogenesis + GOC:cjm + - + - + - + - - + + - - + + Combining with melatonin, N-acetyl-5-methoxytryptamine, to initiate a change in cell activity. Melatonin is a neuroendocrine substance that stimulates the aggregation of melanosomes in melanophores, thus lightening the skin. + molecular_function + GO:0008502 + melatonin receptor activity + + + + + Combining with melatonin, N-acetyl-5-methoxytryptamine, to initiate a change in cell activity. Melatonin is a neuroendocrine substance that stimulates the aggregation of melanosomes in melanophores, thus lightening the skin. + GOC:ai + ISBN:0198506732 + + + + + + + + - - + + - negative regulation of hemostasis + Combining with soluble compounds to initiate a change in cell activity. These receptors are responsible for the sense of taste. + gustatory receptor + molecular_function + GO:0008527 + taste receptor activity + + + + Combining with soluble compounds to initiate a change in cell activity. These receptors are responsible for the sense of taste. + GOC:dph + + + + + + + + + + Combining with a peptide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. + G protein coupled peptide receptor activity + G-protein coupled peptide receptor activity + peptide receptor activity, G protein coupled + peptide receptor activity, G-protein coupled + molecular_function + GO:0008528 + G protein-coupled peptide receptor activity + + + + + Combining with a peptide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. + GOC:dph + GOC:tb + + + + + peptide receptor activity, G-protein coupled + GOC:bf + - + - - + + + - - + - - + + - + - - - + - - + + + + + + - positive regulation of hemostasis + + + + + + + The process whose specific outcome is the progression of the epidermis over time, from its formation to the mature structure. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species. + + biological_process + hypodermis development + GO:0008544 + epidermis development + + + + The process whose specific outcome is the progression of the epidermis over time, from its formation to the mature structure. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species. + GOC:go_curators + UBERON:0001003 + + + + + hypodermis development + GOC:kmv + GOC:rk + - + - + - + - - + + - - - + - - - - - regulation of plasma cell differentiation - + + + + + The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure. + testicular development + testis development + biological_process + GO:0008584 + male gonad development + + + + + The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure. + GOC:jid + + + + + testicular development + GOC:sl + + + + + testis development + GOC:sl + - + - + - + - - + + - - - - + + + + + + + + + + + - - + + - negative regulation of plasma cell differentiation + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the female gonad over time, from its formation to the mature structure. + + GO:0061039 + biological_process + ovarian development + ovary development + GO:0008585 + female gonad development + + + + The process whose specific outcome is the progression of the female gonad over time, from its formation to the mature structure. + GOC:dph + GOC:jid + GOC:tb + + + + + ovarian development + GOC:sl + + + + + ovary development + GOC:sl + - + - + - + - - + + - - - - + + - - + + - positive regulation of plasma cell differentiation - - - - - - - - - carbohydrate derivative metabolic process - - - - - - - - - - carbohydrate derivative biosynthetic process + The process in which anatomical structures of the veins on an imaginal disc-derived wing are generated and organized. + wing vein morphogenesis + biological_process + GO:0008586 + imaginal disc-derived wing vein morphogenesis + + + + The process in which anatomical structures of the veins on an imaginal disc-derived wing are generated and organized. + GOC:mtg_sensu + - + - + - + - - + + - + - + - gene expression involved in extracellular matrix organization - - - - - - - - - primary amino compound metabolic process + The process in which the structures of a photoreceptor cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a photoreceptor cell, a sensory cell that reacts to the presence of light. An example of this is found in Drosophila melanogaster. + biological_process + photoreceptor development + GO:0008594 + photoreceptor cell morphogenesis + + + + The process in which the structures of a photoreceptor cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a photoreceptor cell, a sensory cell that reacts to the presence of light. An example of this is found in Drosophila melanogaster. + GOC:jid + GOC:mah + - + - - - - - - - - - - - - - - + + + - - + + - regulation of flagellated sperm motility + The specification of the anterior/posterior axis of the embryo by the products of genes expressed maternally and genes expressed in the zygote. + biological_process + anterior/posterior axis determination, embryo + GO:0008595 + anterior/posterior axis specification, embryo + + + + The specification of the anterior/posterior axis of the embryo by the products of genes expressed maternally and genes expressed in the zygote. + ISBN:0879694238 + http://fly.ebi.ac.uk/allied-data/lk/interactive-fly/aimain/1aahome.htm + + + + + anterior/posterior axis determination, embryo + GOC:dph + - + - + - + - - + + - - - - - - - - - - - negative regulation of flagellated sperm motility + + + The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. + lipid anabolism + lipid biosynthesis + lipid formation + lipid synthesis + lipogenesis + biological_process + GO:0008610 + lipid biosynthetic process + + + + The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. + GOC:go_curators + + + + + lipogenesis + GOC:sl + - + - + - + - - + + - - - - - - - - regulation of vasculature development + + The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are a group of organic compounds based of the general formula Cx(H2O)y. + GO:0006861 + GO:0008644 + sugar transport + biological_process + GO:0008643 + + + carbohydrate transport + + + + The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are a group of organic compounds based of the general formula Cx(H2O)y. + GOC:ai + - + - + - + - - + + - - - - - - - - - - negative regulation of vasculature development + The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents. + Wikipedia:Amino_acid_synthesis + amino acid biosynthetic process + cellular amino acid anabolism + cellular amino acid biosynthesis + cellular amino acid formation + cellular amino acid synthesis + biological_process + GO:0008652 + cellular amino acid biosynthetic process + + + + The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents. + ISBN:0198506732 + - + - - - organic cyclic compound metabolic process + + + The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism. + jl + 2012-10-17T15:52:35Z + GO:0044243 + GO:0044712 + Wikipedia:Catabolism + breakdown + catabolism + degradation + multicellular organismal catabolic process + biological_process + single-organism catabolic process + GO:0009056 + + + + catabolic process + + + + The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism. + ISBN:0198547684 + - + - - - - organic cyclic compound biosynthetic process + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. + GO:0043285 + GO:0044266 + biopolymer catabolic process + macromolecule breakdown + macromolecule catabolism + macromolecule degradation + multicellular organismal macromolecule catabolic process + biological_process + GO:0009057 + + macromolecule catabolic process + + + + The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. + GOC:mah + + + + + biopolymer catabolic process + GOC:mtg_chebi_dec09 + - + - - - - organonitrogen compound metabolic process + + + The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones. + jl + 2012-10-17T15:52:18Z + GO:0044274 + GO:0044711 + formation + Wikipedia:Anabolism + anabolism + biosynthesis + synthesis + multicellular organismal biosynthetic process + biological_process + single-organism biosynthetic process + GO:0009058 + + + + biosynthetic process + + + + The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones. + GOC:curators + ISBN:0198547684 + - + - - + + + + + + + + + + + + + - organonitrogen compound biosynthetic process - - - - - - - - - - organic substance catabolic process - - - - - - - - - - organic substance biosynthetic process - - - - - - - - - alpha-amino acid metabolic process + The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. + GO:0043284 + biopolymer biosynthetic process + macromolecule anabolism + macromolecule biosynthesis + macromolecule formation + macromolecule synthesis + biological_process + GO:0009059 + + macromolecule biosynthetic process + + + + The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. + GOC:mah + + + + + biopolymer biosynthetic process + GOC:mtg_chebi_dec09 + - + - - - organic hydroxy compound metabolic process + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents. + amino acid catabolic process + cellular amino acid breakdown + cellular amino acid catabolism + cellular amino acid degradation + biological_process + GO:0009063 + cellular amino acid catabolic process + + + + The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents. + GOC:ai + - + - - - - organic hydroxy compound biosynthetic process + + + + + + + + + + + + + + The chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline. + glutamine family amino acid metabolism + biological_process + GO:0009064 + glutamine family amino acid metabolic process + + + + The chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline. + GOC:ai + - + - - - response to oxygen-containing compound + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline. + glutamine family amino acid breakdown + glutamine family amino acid catabolism + glutamine family amino acid degradation + biological_process + GO:0009065 + glutamine family amino acid catabolic process + + + + The chemical reactions and pathways resulting in the breakdown of amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline. + GOC:ai + - + - + - + - - + + - - - - - - - - regulation of cilium-dependent cell motility + + The chemical reactions and pathways resulting in the formation of amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline. + glutamine family amino acid anabolism + glutamine family amino acid biosynthesis + glutamine family amino acid formation + glutamine family amino acid synthesis + biological_process + GO:0009084 + glutamine family amino acid biosynthetic process + + + + The chemical reactions and pathways resulting in the formation of amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline. + GOC:ai + - + - + - + - - + + - - - - - - - - - negative regulation of cilium-dependent cell motility + + The chemical reactions and pathways involving glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. + glycoprotein metabolism + biological_process + GO:0009100 + + glycoprotein metabolic process + + + + The chemical reactions and pathways involving glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. + GOC:go_curators + ISBN:0198506732 + - + - + - + - - + + - - - - - - - - - - - positive regulation of flagellated sperm motility + + The chemical reactions and pathways resulting in the formation of glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. + glycoprotein anabolism + glycoprotein biosynthesis + glycoprotein formation + glycoprotein synthesis + biological_process + GO:0009101 + glycoprotein biosynthetic process + + + + The chemical reactions and pathways resulting in the formation of glycoproteins, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. + GOC:go_curators + ISBN:0198506732 + - + - + - + - - + + - - - - - - - - - regulation of leukocyte differentiation + + + The chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues. + glucan anabolism + glucan biosynthesis + glucan formation + glucan synthesis + biological_process + GO:0009250 + glucan biosynthetic process + + + + The chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues. + GOC:go_curators + - + - + - + - - + + - - - - - - - - - - negative regulation of leukocyte differentiation + + + The chemical reactions and pathways resulting in the breakdown of glucans, polysaccharides consisting only of glucose residues. + glucan breakdown + glucan catabolism + glucan degradation + biological_process + GO:0009251 + glucan catabolic process + + + + The chemical reactions and pathways resulting in the breakdown of glucans, polysaccharides consisting only of glucose residues. + GOC:go_curators + - + - + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus. + response to thermal stimulus + biological_process + GO:0009266 + response to temperature stimulus + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus. + GOC:hb + + + + + + + - + - - + + - - - - - - - - - - positive regulation of leukocyte differentiation + + + The controlled release of proteins from a cell. + GO:0045166 + GO:0045731 + glycoprotein secretion + protein secretion during cell fate commitment + protein secretion resulting in cell fate commitment + biological_process + GO:0009306 + protein secretion + + + + The controlled release of proteins from a cell. + GOC:ai + - + - + - + - - + + - - - - - - - - - - regulation of sperm capacitation + + The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom. + amine metabolism + biological_process + GO:0009308 + + + amine metabolic process + + + + The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom. + GOC:jl + ISBN:0198506732 + - + - + - + - - + + - - - - - - - - - - - negative regulation of sperm capacitation + + The chemical reactions and pathways resulting in the formation of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom. + amine anabolism + amine biosynthesis + amine formation + amine synthesis + biological_process + GO:0009309 + amine biosynthetic process + + + + The chemical reactions and pathways resulting in the formation of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom. + GOC:jl + ISBN:0198506732 + - + - + - + - - + + - - - - - - - - - - - positive regulation of sperm capacitation + The chemical reactions and pathways resulting in the breakdown of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom. + amine breakdown + amine catabolism + amine degradation + biological_process + GO:0009310 + amine catabolic process + + + + The chemical reactions and pathways resulting in the breakdown of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom. + GOC:jl + ISBN:0198506732 + - + - + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation. + response to electromagnetic radiation stimulus + response to radiation stimulus + biological_process + GO:0009314 + Note that 'radiation' refers to electromagnetic radiation of any wavelength. + response to radiation + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation. + GOC:jl + Wikipedia:Electromagnetic_radiation + + + + + + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water. + response to dehydration + response to drought + response to thirst + biological_process + drought tolerance + GO:0009414 + response to water deprivation + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water. + GOC:lr + + + + + + + - + - - + + - - - - - - - - - positive regulation of response to water deprivation + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water. + response to water stimulus + biological_process + GO:0009415 + response to water + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water. + GOC:jl + + + + + response to water stimulus + GOC:dos + - + - + - + - - + + - - - - - - - - - - regulation of chondrocyte differentiation involved in endochondral bone morphogenesis + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light. + biological_process + GO:0009416 + + response to light stimulus + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light. + GOC:go_curators + ISBN:0582227089 + - + - + - + - - + + - - - - - - - - - - positive regulation of chondrocyte development + + + The chemical reactions and pathways involving gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms. + 4-aminobutanoate metabolic process + 4-aminobutanoate metabolism + 4-aminobutyrate metabolic process + 4-aminobutyrate metabolism + GABA metabolic process + GABA metabolism + gamma-aminobutyric acid metabolism + biological_process + GO:0009448 + See also the biological process term 'neurotransmitter metabolic process ; GO:0042133'. + gamma-aminobutyric acid metabolic process + + + + The chemical reactions and pathways involving gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms. + ISBN:0198506732 + - + - + - + - - + + - - - - - - - - - regulation of alcohol biosynthetic process + The chemical reactions and pathways resulting in the formation of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms. + 4-aminobutanoate biosynthesis + 4-aminobutanoate biosynthetic process + 4-aminobutyrate biosynthesis + 4-aminobutyrate biosynthetic process + GABA biosynthesis + GABA biosynthetic process + gamma-aminobutyric acid anabolism + gamma-aminobutyric acid biosynthesis + gamma-aminobutyric acid formation + gamma-aminobutyric acid synthesis + biological_process + GO:0009449 + See also the biological process term 'neurotransmitter biosynthetic process ; GO:0042136'. + gamma-aminobutyric acid biosynthetic process + + + + The chemical reactions and pathways resulting in the formation of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms. + GOC:ai + - + - + - + - - + + - - - - - - - - - - negative regulation of alcohol biosynthetic process + The chemical reactions and pathways resulting in the breakdown of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms. + MetaCyc:4AMINOBUTMETAB-PWY + 4-aminobutanoate catabolic process + 4-aminobutanoate catabolism + 4-aminobutyrate catabolic process + 4-aminobutyrate catabolism + GABA catabolic process + GABA catabolism + gamma-aminobutyric acid breakdown + gamma-aminobutyric acid catabolism + gamma-aminobutyric acid degradation + biological_process + GO:0009450 + See also the biological process term 'neurotransmitter catabolic process ; GO:0042135'. + gamma-aminobutyric acid catabolic process + + + + The chemical reactions and pathways resulting in the breakdown of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms. + GOC:ai + - + - + - + - - + + + + + + - - - - - + + - positive regulation of alcohol biosynthetic process + The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy). + https://github.com/geneontology/go-ontology/issues/20176 + Wikipedia:Fertilisation + syngamy + biological_process + GO:0009566 + fertilization + + + + The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy). + GOC:tb + ISBN:0198506732 + - + - - - - - - - - - - - - - + + + + The series of events in which an external stimulus is received by a cell and converted into a molecular signal. + biological_process + perception of external stimulus + GO:0009581 + detection of external stimulus + + + + + The series of events in which an external stimulus is received by a cell and converted into a molecular signal. + GOC:hb + + + + + + + + + + The series of events in which an (non-living) abiotic stimulus is received by a cell and converted into a molecular signal. + biological_process + perception of abiotic stimulus + GO:0009582 + detection of abiotic stimulus + + + + + The series of events in which an (non-living) abiotic stimulus is received by a cell and converted into a molecular signal. + GOC:hb + + + + + + + + + + + The series of events in which a light stimulus (in the form of photons) is received and converted into a molecular signal. + detection of light + biological_process + perception of light + GO:0009583 + detection of light stimulus + + + + + The series of events in which a light stimulus (in the form of photons) is received and converted into a molecular signal. + GOC:go_curators + + + + + + + + + The series of events in which a visible light stimulus is received by a cell and converted into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm. + biological_process + perception of visible light + GO:0009584 + detection of visible light + + + + + The series of events in which a visible light stimulus is received by a cell and converted into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm. + GOC:go_curators + ISBN:0198506732 + + + + + + + + + + + The series of events in which a gravitational stimulus is received and converted into a molecular signal. + biological_process + perception of gravity + GO:0009590 + detection of gravity + + + + + The series of events in which a gravitational stimulus is received and converted into a molecular signal. + GOC:dos + GOC:hb + + + + + + + + - - + + - regulation of bone development + The series of events in which a chemical stimulus is received by a cell and converted into a molecular signal. + chemoperception + detection of chemical substance + biological_process + chemoreception + perception of chemical stimulus + perception of chemical substance + GO:0009593 + detection of chemical stimulus + + + + The series of events in which a chemical stimulus is received by a cell and converted into a molecular signal. + GOC:jl + - + - + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus. + response to environmental stimulus + biological_process + GO:0009605 + + + + Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. + response to external stimulus + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus. + GOC:hb + + + + + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism. + response to biotic stress + biological_process + GO:0009607 + + + + Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. + response to biotic stimulus + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism. + GOC:hb + + + + + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism. + GO:0002245 + physiological response to wounding + biological_process + GO:0009611 + response to wounding + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism. + GOC:go_curators + + + + + + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus. + mechanical stimulus response + biological_process + chemi-mechanical coupling + GO:0009612 + response to mechanical stimulus + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus. + GOC:hb + + + + + + + - + - - + + - - - - - - - - - - negative regulation of bone development + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium. + GO:0009618 + GO:0009680 + response to bacteria + biological_process + GO:0009617 + response to bacterium + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium. + GOC:hb + - + - + - + - - + + - - - + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a fungus. + GO:0009621 + response to fungi + biological_process + GO:0009620 + response to fungus + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a fungus. + GOC:hb + + + + + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (not derived from living organisms) stimulus. + https://github.com/geneontology/go-ontology/issues/16572 + response to abiotic stress + biological_process + GO:0009628 + + + + Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. + response to abiotic stimulus + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (not derived from living organisms) stimulus. + GOC:hb + + + + + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gravitational stimulus. + response to gravitational stimulus + biological_process + GO:0009629 + response to gravity + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gravitational stimulus. + GOC:hb + + + + + + + + - - + + - positive regulation of bone development + + + The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form. + embryogenesis and morphogenesis + Wikipedia:Morphogenesis + anatomical structure organization + morphogenesis + biological_process + GO:0009653 + anatomical structure morphogenesis + + + + The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form. + GOC:go_curators + ISBN:0521436125 + - + - + - + - - + + - - - - - - - - regulation of response to wounding + + The chemical reactions and pathways involving a compound containing a pyrocatechol (1,2-benzenediol) nucleus or substituent. + biological_process + catechol metabolic process + catechol metabolism + GO:0009712 + catechol-containing compound metabolic process + + + + The chemical reactions and pathways involving a compound containing a pyrocatechol (1,2-benzenediol) nucleus or substituent. + GOC:sm + ISBN:0198547684 + - + - + - + - - + + - - - - - - - - - negative regulation of response to wounding + The chemical reactions and pathways resulting in the formation of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent. + biological_process + catechol anabolism + catechol biosynthesis + catechol biosynthetic process + catechol formation + catechol synthesis + GO:0009713 + catechol-containing compound biosynthetic process + + + + The chemical reactions and pathways resulting in the formation of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent. + GOC:go_curators + - + - + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism. + biological_process + GO:0009719 + + + Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. + response to endogenous stimulus + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism. + GOC:sm + + + + + + + - + - - + + - - - - - - - - - positive regulation of response to wounding + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus. + response to hormone stimulus + biological_process + growth regulator + GO:0009725 + response to hormone + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus. + GOC:jl + + + + + response to hormone stimulus + GOC:dos + - + - + - + - - + + - - - - - - - - regulation of leukocyte cell-cell adhesion + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus. + response to carbohydrate stimulus + biological_process + GO:0009743 + response to carbohydrate + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus. + GOC:jl + + + + + response to carbohydrate stimulus + GOC:dos + - + - + - + - - + + - - - - - - - - - negative regulation of leukocyte cell-cell adhesion + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus. + response to hexose stimulus + biological_process + GO:0009746 + response to hexose + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus. + GOC:jl + + + + + response to hexose stimulus + GOC:dos + - + - + - + - - + + - - + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus. + response to glucose stimulus + biological_process + GO:0009749 + response to glucose + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus. + GOC:jl + + + + + response to glucose stimulus + GOC:dos + + + + + + + + - - + + - positive regulation of leukocyte cell-cell adhesion + The series of molecular signals mediated by the detection of a hormone. + hormone mediated signalling + biological_process + GO:0009755 + hormone-mediated signaling pathway + + + + The series of molecular signals mediated by the detection of a hormone. + GOC:sm + - + - + - + - - - - - - - - - - regulation of chondrocyte hypertrophy + Any process that modulates the frequency, rate or extent of asymmetric cell division. + biological_process + GO:0009786 + regulation of asymmetric cell division + + + + Any process that modulates the frequency, rate or extent of asymmetric cell division. + GOC:lr + - + - + - + - - + + - - - - + + + + The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant. + GO:0009795 + embryogenesis and morphogenesis + Wikipedia:Embryogenesis + embryogenesis + embryonal development + biological_process + GO:0009790 + + + + embryo development + + + + + The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant. + GOC:go_curators + GOC:isa_complete + GOC:mtg_sensu + + + + + + + + - - + + - negative regulation of chondrocyte hypertrophy + The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development. + biological_process + GO:0009791 + + post-embryonic development + + + + The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development. + GOC:go_curators + - + - - - - - - - - - - - - - - - - + + - - + + - positive regulation of chondrocyte hypertrophy + + + + + + + The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell. + embryogenesis + biological_process + GO:0009792 + embryo development ending in birth or egg hatching + + + + The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell. + GOC:go_curators + GOC:isa_complete + GOC:mtg_sensu + - + - - - - - - - - - - - - - - + + + The establishment, maintenance and elaboration of a pattern along a line or around a point. + biological_process + axis determination + GO:0009798 + axis specification + + + + + The establishment, maintenance and elaboration of a pattern along a line or around a point. + GOC:dph + GOC:go_curators + GOC:isa_complete + + + + + + + + - + - meiotic cell cycle process + The process that results in the patterns of cell differentiation that will arise in an embryo. + embryonic pattern biosynthesis + embryonic pattern formation + biological_process + ventral/lateral system + GO:0009880 + embryonic pattern specification + + + + The process that results in the patterns of cell differentiation that will arise in an embryo. + GOC:go_curators + ISBN:0521436125 + - + - - - - - - - - - - - - - + + - - + + - regulation of extracellular matrix organization + The process, occurring after animal embryonic development, by which anatomical structures are generated and organized. + post-embryonic morphogenesis of an anatomical structure + biological_process + GO:0009886 + post-embryonic animal morphogenesis + + + + The process, occurring after animal embryonic development, by which anatomical structures are generated and organized. + GOC:go_curators + - + - + - + - - + + - - + + - - + + - negative regulation of extracellular matrix organization + Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. + histogenesis and organogenesis + biological_process + GO:0009887 + animal organ morphogenesis + + + + Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. + GOC:dgh + GOC:go_curators + ISBN:0471245208 + ISBN:0721662544 + - + - + - + - - + + - - + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + - - + + - positive regulation of extracellular matrix organization - - - - - - - - - mononuclear cell differentiation + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure. + + + + + + histogenesis and organogenesis + Wikipedia:Histogenesis + histogenesis + biological_process + GO:0009888 + tissue development + + + + The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure. + ISBN:0471245208 + - + - + - + - - - - - - - - regulation of cell maturation + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances. + regulation of anabolism + regulation of biosynthesis + regulation of formation + regulation of synthesis + biological_process + GO:0009889 + regulation of biosynthetic process + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances. + GOC:go_curators + - + - + - + - - - - - - - - - negative regulation of cell maturation + + + Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances. + down regulation of biosynthetic process + down-regulation of biosynthetic process + downregulation of biosynthetic process + negative regulation of anabolism + negative regulation of biosynthesis + negative regulation of formation + negative regulation of synthesis + inhibition of biosynthetic process + biological_process + GO:0009890 + negative regulation of biosynthetic process + + + + Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances. + GOC:go_curators + - + - + - + - - - - - - - - - positive regulation of cell maturation + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances. + positive regulation of anabolism + positive regulation of biosynthesis + positive regulation of formation + positive regulation of synthesis + up regulation of biosynthetic process + up-regulation of biosynthetic process + upregulation of biosynthetic process + activation of biosynthetic process + stimulation of biosynthetic process + biological_process + GO:0009891 + positive regulation of biosynthetic process + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances. + GOC:go_curators + - + - + - - + + - - - - - - - - - - regulation of lactation + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. + GO:0044252 + down regulation of metabolic process + down-regulation of metabolic process + downregulation of metabolic process + negative regulation of metabolism + negative regulation of organismal metabolism + inhibition of metabolic process + inhibition of organismal metabolic process + negative regulation of multicellular organismal metabolic process + biological_process + GO:0009892 + negative regulation of metabolic process + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. + GOC:go_curators + - + - + - - + + - - - - - - - - - - - negative regulation of lactation + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. + GO:0044253 + positive regulation of metabolism + up regulation of metabolic process + up-regulation of metabolic process + upregulation of metabolic process + activation of metabolic process + positive regulation of multicellular organismal metabolic process + positive regulation of organismal metabolism + stimulation of metabolic process + stimulation of organismal metabolic process + up-regulation of organismal metabolic process + biological_process + GO:0009893 + positive regulation of metabolic process + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. + GOC:go_curators + - + - + - - + + - - - - - - - - - - - positive regulation of lactation + + Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of substances. + regulation of breakdown + regulation of catabolism + regulation of degradation + biological_process + GO:0009894 + regulation of catabolic process + + + + Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of substances. + GOC:go_curators + - + - + - - + + - - - - - - - - regulation of blood circulation + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances. + down regulation of catabolic process + down-regulation of catabolic process + downregulation of catabolic process + negative regulation of breakdown + negative regulation of catabolism + negative regulation of degradation + inhibition of catabolic process + biological_process + GO:0009895 + negative regulation of catabolic process + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances. + GOC:go_curators + - + - + - - + + - - - - - - - - - negative regulation of blood circulation + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances. + positive regulation of breakdown + positive regulation of catabolism + positive regulation of degradation + up regulation of catabolic process + up-regulation of catabolic process + upregulation of catabolic process + activation of catabolic process + stimulation of catabolic process + biological_process + GO:0009896 + positive regulation of catabolic process + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances. + GOC:go_curators + - + - + - + - - + + - - + - - + + - positive regulation of blood circulation + The process in which a relatively unspecialized cell acquires specialized features of an epidermal cell, any of the cells making up the epidermis. + GO:0043355 + biological_process + hypodermal cell differentiation + GO:0009913 + epidermal cell differentiation + + + + The process in which a relatively unspecialized cell acquires specialized features of an epidermal cell, any of the cells making up the epidermis. + GOC:dph + GOC:go_curators + GOC:mtg_sensu + GOC:sdb_2009 + GOC:tb + + + + + hypodermal cell differentiation + GOC:kmv + GOC:rk + - + - + + + + The directed movement of hormones into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + biological_process + GO:0009914 + + hormone transport + + + + + The directed movement of hormones into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:tb + + + + + + + + + + + + + + + The establishment, maintenance and elaboration of the anterior/posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism. + biological_process + anterior/posterior axis determination + GO:0009948 + anterior/posterior axis specification + + + + + The establishment, maintenance and elaboration of the anterior/posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism. + GOC:dph + GOC:go_curators + GOC:tb + + + + + anterior/posterior axis determination + GOC:dph + + + + + + + + + The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism. + biological_process + anterior/posterior pattern formation + GO:0009952 + anterior/posterior pattern specification + + + + + The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism. + GOC:dph + GOC:go_curators + GOC:isa_complete + GOC:tb + + + + + + + - + - - - - - - - - - regulation of secretion by cell + + + + Any process that modulates the frequency, rate or extent of signal transduction. + GO:0035466 + biological_process + regulation of signaling pathway + regulation of signalling pathway + GO:0009966 + regulation of signal transduction + + + + Any process that modulates the frequency, rate or extent of signal transduction. + GOC:sm + + + + + regulation of signalling pathway + GOC:mah + - + - + - - + + - - - - - - - - - - negative regulation of secretion by cell + + + + + Any process that activates or increases the frequency, rate or extent of signal transduction. + GO:0035468 + up regulation of signal transduction + up-regulation of signal transduction + upregulation of signal transduction + activation of signal transduction + stimulation of signal transduction + biological_process + positive regulation of signaling pathway + positive regulation of signalling pathway + GO:0009967 + positive regulation of signal transduction + + + + Any process that activates or increases the frequency, rate or extent of signal transduction. + GOC:sm + + + + + positive regulation of signalling pathway + GOC:mah + - + - + - - + + - - - - - - - - - - positive regulation of secretion by cell + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction. + GO:0035467 + down regulation of signal transduction + down-regulation of signal transduction + downregulation of signal transduction + inhibition of signal transduction + biological_process + negative regulation of signaling pathway + negative regulation of signalling pathway + GO:0009968 + negative regulation of signal transduction + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction. + GOC:sm + + + + + negative regulation of signalling pathway + GOC:mah + - + - + + + + Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. + jl + 2012-12-11T16:56:55Z + GO:0008151 + GO:0044763 + GO:0050875 + cell physiology + cellular physiological process + cell growth and/or maintenance + biological_process + single-organism cellular process + GO:0009987 + + + cellular process + + + + + Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. + GOC:go_curators + GOC:isa_complete + + + + + + + - + - - + + - - - extracellular vesicle + + Any process involved in the maintenance of an internal steady state of water within a cell. + biological_process + cellular osmoregulation + GO:0009992 + cellular water homeostasis + + + + Any process involved in the maintenance of an internal steady state of water within a cell. + GOC:dph + GOC:tb + + + + + cellular osmoregulation + GOC:dph + GOC:tb + - + - + - + - - + + - - + + - - + + - regulation of hemopoiesis + The process in which a relatively unspecialized immature germ cell acquires the specialized features of a mature female gamete. + oocyte cell differentiation + biological_process + GO:0009994 + oocyte differentiation + + + + The process in which a relatively unspecialized immature germ cell acquires the specialized features of a mature female gamete. + GOC:go_curators + GOC:mtg_sensu + - + - + - + - - + + - - - - + - - + + - negative regulation of hemopoiesis + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires the specialized features of a glial cell. + GO:0007404 + GO:0043360 + glia cell differentiation + neuroglia differentiation + biological_process + GO:0010001 + glial cell differentiation + + + + The process in which a relatively unspecialized cell acquires the specialized features of a glial cell. + GOC:go_curators + GOC:mtg_sensu + - + - + + + A complex and coordinated series of cellular movements, including germ band extension, that occurs at the end of cleavage during embryonic development. An example of this process is found in Drosophila melanogaster. + biological_process + GO:0010004 + gastrulation involving germ band extension + + + + + A complex and coordinated series of cellular movements, including germ band extension, that occurs at the end of cleavage during embryonic development. An example of this process is found in Drosophila melanogaster. + GOC:go_curators + GOC:mtg_sensu + + + + + + + - + - - + + - - - - - - - - - - - positive regulation of hemopoiesis + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus. + GO:1990367 + process resulting in tolerance to organic substance + biological_process + GO:0010033 + response to organic substance + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus. + GOC:sm + PMID:23356676 + - + - + - + - - + + - - - - - - - - - negative regulation of anion transport + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus. + biological_process + GO:0010035 + response to inorganic substance + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus. + GOC:sm + - + - + - + - - + + - - - - - - - - - positive regulation of anion transport + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus. + biological_process + GO:0010037 + response to carbon dioxide + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus. + GOC:sm + - + - + - + - - + + - - - - - - - - - negative regulation of respiratory gaseous exchange + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus. + response to metal + response to heavy metal + biological_process + heavy metal sensitivity/resistance + GO:0010038 + response to metal ion + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus. + GOC:sm + - + - + - + - - + + - - - - - - - - - positive regulation of respiratory gaseous exchange + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus. + response to iron + biological_process + GO:0010039 + response to iron ion + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus. + GOC:sm + - + - + - + - - + + - - - - - - - - - - positive regulation of vasculature development + The division of the zygote into two daughter cells that will adopt developmentally distinct potentials. + biological_process + zygote asymmetric cytokinesis + GO:0010070 + zygote asymmetric cell division + + + + The division of the zygote into two daughter cells that will adopt developmentally distinct potentials. + GOC:tb + - + - + - + - - + + - - + + - - + + - negative regulation of sensory perception of pain + The regionalization process that specifies animal organ primordium boundaries resulting in a restriction of organogenesis to a limited spatial domain and keeping the organ separate from surrounding tissues. + GO:0048862 + organ boundary specification + biological_process + GO:0010160 + formation of animal organ boundary + + + + The regionalization process that specifies animal organ primordium boundaries resulting in a restriction of organogenesis to a limited spatial domain and keeping the organ separate from surrounding tissues. + GOC:dph + GOC:isa_complete + PMID:9611175 + - + - + - + - - + + - - - - - - - - - positive regulation of sensory perception of pain + + + The process in which the anatomical structures of the soma are generated and organized. + biological_process + GO:0010171 + body morphogenesis + + + + The process in which the anatomical structures of the soma are generated and organized. + GOC:ems + ISBN:0140512888 + - + - + - + - - + + - - - - - - - - axon cytoplasm + A process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chitin stimulus. + biological_process + GO:0010200 + response to chitin + + + + A process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chitin stimulus. + GOC:sm + - + - + - + - - + + - - - - - - - - - - regulation of bile acid metabolic process + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond. + response to organic nitrogen + biological_process + GO:0010243 + response to organonitrogen compound + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond. + PMID:9869419 + - + - + - + - - + + - - - - - - - - - - - negative regulation of bile acid metabolic process + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endomembrane system. + endomembrane organization + endomembrane system organisation + biological_process + GO:0010256 + + endomembrane system organization + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endomembrane system. + GOC:mah + GOC:sm + + + + + endomembrane system organisation + GOC:mah + - + - + - - + + - - - - - - - - - - - positive regulation of bile acid metabolic process + Any process that modulates the frequency, rate or extent of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. + biological_process + GO:0010453 + regulation of cell fate commitment + + + + Any process that modulates the frequency, rate or extent of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. + GOC:dph + GOC:tb + - + - + - - + + - - - - - - - - - - regulation of smooth muscle contraction involved in micturition + + Any process that stops, prevents or reduces the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. + biological_process + GO:0010454 + negative regulation of cell fate commitment + + + + Any process that stops, prevents or reduces the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. + GOC:dph + GOC:tb + - + - + - - + + - - - - - - - - - negative regulation of smooth muscle contraction involved in micturition + + Any process that activates, maintains or increases the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. + biological_process + GO:0010455 + positive regulation of cell fate commitment + + + + Any process that activates, maintains or increases the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. + GOC:dph + GOC:tb + - + - + - + - - + + - - - - - - - - - positive regulation of smooth muscle contraction involved in micturition + + The multiplication or reproduction of cells, resulting in the expansion of the dorsal spinal cord cell population. + biological_process + GO:0010456 + cell proliferation in dorsal spinal cord + + + + The multiplication or reproduction of cells, resulting in the expansion of the dorsal spinal cord cell population. + GOC:dph + GOC:tb + - + - + - + - - + + - - - - - - - - regulation of calcitonin secretion + + The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. + biological_process + GO:0010463 + mesenchymal cell proliferation + + + + The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. + GOC:dph + GOC:tb + - + - + - - + + - - - - - - - - - negative regulation of calcitonin secretion + + Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. + biological_process + GO:0010464 + regulation of mesenchymal cell proliferation + + + + Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. + GOC:dph + GOC:tb + - + - + + + The process in which a gene's sequence is converted into a mature gene product (protein or RNA). This includes the production of an RNA transcript and its processing, translation and maturation for protein-coding genes. + https://github.com/geneontology/go-ontology/issues/22557 + Wikipedia:Gene_expression + biological_process + GO:0010467 + + gene expression + + + + + The process in which a gene's sequence is converted into a mature gene product (protein or RNA). This includes the production of an RNA transcript and its processing, translation and maturation for protein-coding genes. + GOC:txnOH-2018 + PMID:25934543 + PMID:31580950 + + + + + + + - - + + - - - - - - - - - positive regulation of calcitonin secretion + Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). + https://github.com/geneontology/go-ontology/issues/22557 + Wikipedia:Regulation_of_gene_expression + regulation of protein expression + biological_process + gene regulation + regulation of gene product expression + GO:0010468 + This class covers any process that regulates the rate of production of a mature gene product, and so includes processes that regulate that rate by regulating the level, stability or availability of intermediates in the process of gene expression. For example, it covers any process that regulates the level, stability or availability of mRNA or circRNA for translation and thereby regulates the rate of production of the encoded protein via translation. + regulation of gene expression + + + + Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). + GOC:txnOH-2018 + + + + + gene regulation + GOC:cjm + - + - + - - + + - - - - - - - - - negative regulation of establishment of protein localization + + + Any process that modulates the frequency, rate or extent of a signaling receptor activity. Receptor activity is when a molecule combines with an extracellular or intracellular messenger to initiate a change in cell activity. + regulation of receptor activity + regulation of signalling receptor activity + biological_process + GO:0010469 + regulation of signaling receptor activity + + + + Any process that modulates the frequency, rate or extent of a signaling receptor activity. Receptor activity is when a molecule combines with an extracellular or intracellular messenger to initiate a change in cell activity. + GOC:dph + GOC:tb + - + - + - - + + - - - - - - - - - positive regulation of establishment of protein localization + + + Any process that modulates the rate or extent of gastrulation. Gastrulation is the complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. + biological_process + GO:0010470 + regulation of gastrulation + + + + Any process that modulates the rate or extent of gastrulation. Gastrulation is the complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. + GOC:dph + GOC:tb + - + - + - + - - + + - - - - - - - - - regulation of epithelial tube formation + Any process resulting in the physical partitioning and separation of an epidermal cell, any of the cells making up the epidermis, into daughter cells. + biological_process + hypodermal cell division + GO:0010481 + epidermal cell division + + + + Any process resulting in the physical partitioning and separation of an epidermal cell, any of the cells making up the epidermis, into daughter cells. + PMID:17450124 + + + + + hypodermal cell division + GOC:kmv + GOC:rk + - + - + - - + + - - - - - - - - - - negative regulation of epithelial tube formation + Any process that modulates the frequency, rate or extent of the physical partitioning and separation of an epidermal cell into daughter cells. An epidermal cell is any of the cells that make up the epidermis. + biological_process + regulation of hypodermal cell division + GO:0010482 + regulation of epidermal cell division + + + + Any process that modulates the frequency, rate or extent of the physical partitioning and separation of an epidermal cell into daughter cells. An epidermal cell is any of the cells that make up the epidermis. + PMID:17450124 + + + + + regulation of hypodermal cell division + GOC:kmv + GOC:rk + - + - + - - + + - - - - - - - - - - positive regulation of epithelial tube formation + Any process that modulates the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. + biological_process + GO:0010543 + regulation of platelet activation + + + + Any process that modulates the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. + GOC:BHF + GOC:dph + GOC:tb + - + - + - - + + - - - - - - - - regulation of morphogenesis of an epithelium + + Any process that decreases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. + biological_process + GO:0010544 + negative regulation of platelet activation + + + + Any process that decreases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. + GOC:BHF + GOC:dph + GOC:tb + - + - + - - + + - - - - - - - - - negative regulation of morphogenesis of an epithelium + + + Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. + biological_process + GO:0010556 + regulation of macromolecule biosynthetic process + + + + Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. + GOC:dph + GOC:tb + - + - + - + - - - - - - - - - positive regulation of morphogenesis of an epithelium + + + + Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. + biological_process + GO:0010557 + positive regulation of macromolecule biosynthetic process + + + + Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. + GOC:dph + GOC:tb + - + - + - - + + - - - - - - - - - - regulation of blood vessel branching + + + + Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. + biological_process + GO:0010558 + negative regulation of macromolecule biosynthetic process + + + + Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. + GOC:dph + GOC:tb + - + - + - - + + - - - - - - - - - - negative regulation of vessel branching + Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. + biological_process + GO:0010559 + regulation of glycoprotein biosynthetic process + + + + Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. + GOC:dph + GOC:tb + - + - + - + - - - - - - - - - - positive regulation of blood vessel branching + Any process that increases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. + biological_process + GO:0010560 + positive regulation of glycoprotein biosynthetic process + + + + Any process that increases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. + GOC:dph + GOC:tb + - + - + - + - - - - - - - - - - negative regulation of saliva secretion + Any process that decreases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. + biological_process + GO:0010561 + negative regulation of glycoprotein biosynthetic process + + + + Any process that decreases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide. + GOC:dph + GOC:tb + - + - + - + - - - - - - - - - regulation of detection of mechanical stimulus involved in sensory perception of touch + + Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. + biological_process + GO:0010564 + regulation of cell cycle process + + + + Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. + GOC:dph + GOC:tb + - + - + - - + + - - - - - - - - - - negative regulation of detection of mechanical stimulus involved in sensory perception of touch + + Any process that modulates the chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups. + biological_process + GO:0010565 + regulation of cellular ketone metabolic process + + + + Any process that modulates the chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups. + GOC:dph + GOC:tb + - + - + - - + + - - - - - - - - - - positive regulation of detection of mechanical stimulus involved in sensory perception of touch + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a ketone, carried out by individual cells. + biological_process + GO:0010566 + regulation of ketone biosynthetic process + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a ketone, carried out by individual cells. + GOC:dph + GOC:tb + - + - + - + - - - - - - - - - - regulation of oogenesis + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a ketone, carried out by individual cells. + biological_process + GO:0010567 + regulation of ketone catabolic process + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a ketone, carried out by individual cells. + GOC:dph + GOC:tb + - + - + - - + + - - - - - - - - - - - negative regulation of oogenesis + Any process that increases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. + biological_process + GO:0010572 + positive regulation of platelet activation + + + + Any process that increases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. + GOC:dph + GOC:sl + GOC:tb + - + - + - - + + - - - - - - - - - - - positive regulation of oogenesis + Any process that modulates the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium. + biological_process + GO:0010594 + regulation of endothelial cell migration + + + + Any process that modulates the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium. + GOC:BHF + GOC:dph + GOC:tb + - + - + - - + + - - - - - - - - regulation of mesoderm formation + Any process that increases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium. + biological_process + GO:0010595 + positive regulation of endothelial cell migration + + + + Any process that increases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium. + GOC:BHF + GOC:dph + GOC:tb + - + - + - + - - - - - - - - - negative regulation of mesoderm formation + Any process that decreases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium. + biological_process + GO:0010596 + negative regulation of endothelial cell migration + + + + Any process that decreases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium. + GOC:BHF + GOC:dph + GOC:tb + - + - + - + - - - - - - - - - positive regulation of mesoderm formation + + + Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. + biological_process + GO:0010604 + positive regulation of macromolecule metabolic process + + + + Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. + GOC:dph + GOC:tb + - + - + - - + + - - - - - - - - - regulation of gonad development + + + Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. + biological_process + GO:0010605 + negative regulation of macromolecule metabolic process + + + + Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. + GOC:dph + GOC:tb + - + - + - - + + - - - - - - - - - - - negative regulation of gonad development + + Any process that modulates the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division. + biological_process + GO:0010611 + regulation of cardiac muscle hypertrophy + + + + Any process that modulates the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division. + GOC:dph + GOC:tb + - + - + - - + + - - - - - - - - - - - positive regulation of gonad development + Any process that modulates the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. + biological_process + GO:0010612 + regulation of cardiac muscle adaptation + + + + Any process that modulates the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. + GOC:dph + GOC:tb + - + - + - - + + - - - - - - - - regulation of lipid localization + Any process that increases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division. + biological_process + GO:0010613 + positive regulation of cardiac muscle hypertrophy + + + + Any process that increases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division. + GOC:BHF + GOC:dph + GOC:tb + - + - + - + - - - - - - - - - negative regulation of lipid localization + Any process that decreases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division. + biological_process + GO:0010614 + negative regulation of cardiac muscle hypertrophy + + + + Any process that decreases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division. + GOC:BHF + GOC:dph + GOC:tb + - + - + - + - - - - - - - - - positive regulation of lipid localization + Any process that increases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. + biological_process + GO:0010615 + positive regulation of cardiac muscle adaptation + + + + Any process that increases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. + GOC:BHF + GOC:dph + GOC:tb + - + - - - adaptive thermogenesis + + + + + + + + + + + + + Any process that decreases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. + biological_process + GO:0010616 + negative regulation of cardiac muscle adaptation + + + + Any process that decreases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. + GOC:BHF + GOC:dph + GOC:tb + - + - + - + - - - - - - - - - regulation of multicellular organismal development + Any process that modulates the frequency or rate of multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system. + biological_process + GO:0010624 + regulation of Schwann cell proliferation + + + + Any process that modulates the frequency or rate of multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system. + GOC:dph + GOC:sl + GOC:tb + - + - + - - + + - - - - - - - - regulation of animal organ morphogenesis + Any process that increases the frequency or rate of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system. + biological_process + GO:0010625 + positive regulation of Schwann cell proliferation + + + + Any process that increases the frequency or rate of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system. + GOC:dph + GOC:sl + GOC:tb + - + - + - - + + - - - - - - - - regulation of stem cell division + Any process that decreases the frequency or extent of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system. + biological_process + GO:0010626 + negative regulation of Schwann cell proliferation + + + + Any process that decreases the frequency or extent of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system. + GOC:dph + GOC:sl + GOC:tb + - + - + - - + + - - - - - - - - regulation of response to water deprivation + Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). + https://github.com/geneontology/go-ontology/issues/22557 + biological_process + GO:0010628 + positive regulation of gene expression + + + + Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). + GOC:txnOH-2018 + - + - + - - + + - - - - - - - - - regulation of cellular macromolecule biosynthetic process + Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). + https://github.com/geneontology/go-ontology/issues/22557 + biological_process + gene silencing + GO:0010629 + This term covers any process that negatively regulates the rate of production of a mature gene product, and so includes processes that negatively regulate that rate by reducing the level, stability or availability of intermediates in the process of gene expression. For example, it covers any process that reduces the level, stability or availability of mRNA or circRNA for translation and thereby reduces the rate of production of the encoded protein via translation. + negative regulation of gene expression + + + + Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product (protein or RNA). + GOC:txnOH-2018 + - + - + - + - - + + - - - + - - + + - negative regulation of cellular macromolecule biosynthetic process + The orderly movement of an epithelial cell from one site to another, often during the development of a multicellular organism. + biological_process + GO:0010631 + epithelial cell migration + + + + The orderly movement of an epithelial cell from one site to another, often during the development of a multicellular organism. + GOC:BHF + GOC:ascb_2009 + GOC:dph + GOC:tb + - + - + - + - - - + - regulation of cell motility + Any process that modulates the frequency, rate or extent of epithelial cell migration. + biological_process + GO:0010632 + regulation of epithelial cell migration + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate or extent of epithelial cell migration. + GOC:BHF + GOC:dph + GOC:tb + - + - + - + - - - - + - negative regulation of cell motility + Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell migration. + biological_process + GO:0010633 + negative regulation of epithelial cell migration + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell migration. + GOC:BHF + GOC:dph + GOC:tb + - + - + - + - - - - - - - - - - positive regulation of cell motility + Any process that activates or increases the frequency, rate or extent of epithelial cell migration. + biological_process + GO:0010634 + positive regulation of epithelial cell migration + + + + Any process that activates or increases the frequency, rate or extent of epithelial cell migration. + GOC:BHF + GOC:dph + GOC:tb + - + - + - + - - - - - - - - - positive regulation of cilium-dependent cell motility + + + Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle. + positive regulation of organelle organisation + biological_process + positive regulation of organelle organization and biogenesis + GO:0010638 + positive regulation of organelle organization + + + + Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle. + GOC:dph + GOC:tb + + + + + positive regulation of organelle organisation + GOC:mah + + + + + positive regulation of organelle organization and biogenesis + GOC:mah + - + - + - + - - - - - - - - - negative regulation of blood vessel morphogenesis + + + Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle. + negative regulation of organelle organisation + biological_process + negative regulation of organelle organization and biogenesis + GO:0010639 + negative regulation of organelle organization + + + + Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle. + GOC:dph + GOC:tb + + + + + negative regulation of organelle organisation + GOC:mah + + + + + negative regulation of organelle organization and biogenesis + GOC:mah + - + - + - + - - - - - - - - - regulation of female gonad development + + Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. + biological_process + GO:0010646 + regulation of cell communication + + + + Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. + GOC:dph + GOC:tb + - + - + - - + + - - - - - - - - - negative regulation of female gonad development + + + Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. + biological_process + GO:0010647 + positive regulation of cell communication + + + + Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. + GOC:dph + GOC:tb + - + - + - - + + - - - - - - - - - positive regulation of female gonad development + + + Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. + biological_process + GO:0010648 + negative regulation of cell communication + + + + Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment. + GOC:dph + GOC:tb + - + - + - + - - + + - + - - + + - regulation of glutamate metabolic process + The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an ectodermal cell. Differentiation includes the processes involved in commitment of a cell to a specific fate. + biological_process + GO:0010668 + ectodermal cell differentiation + + + + The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an ectodermal cell. Differentiation includes the processes involved in commitment of a cell to a specific fate. + GOC:dph + GOC:tb + - + - + - - + + - - - - - - - - - negative regulation of glutamate metabolic process + + + Any process that modulates the rate, extent or frequency of the chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells. + biological_process + GO:0010675 + regulation of cellular carbohydrate metabolic process + + + + Any process that modulates the rate, extent or frequency of the chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells. + GOC:dph + GOC:tb + - + - + - + - - - - - - - - - positive regulation of glutamate metabolic process + + + + Any process that increases the rate, extent or frequency of the chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells. + biological_process + GO:0010676 + positive regulation of cellular carbohydrate metabolic process + + + + Any process that increases the rate, extent or frequency of the chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells. + GOC:dph + GOC:tb + - + - + - - + + - - - - - - - - regulation of reproductive process + + + + Any process that decreases the rate, extent or frequency of the chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells. + biological_process + GO:0010677 + negative regulation of cellular carbohydrate metabolic process + + + + Any process that decreases the rate, extent or frequency of the chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells. + GOC:dph + GOC:tb + - + - + - + - - - - - - - - - negative regulation of reproductive process + + + Any process that decreases the frequency, rate or extent of the regulated release of norepinephrine. + biological_process + GO:0010700 + negative regulation of norepinephrine secretion + + + + Any process that decreases the frequency, rate or extent of the regulated release of norepinephrine. + GOC:dph + GOC:tb + - + - + - + - - - - - - - - - positive regulation of reproductive process + + + Any process that increases the frequency, rate or extent of the regulated release of norepinephrine. + biological_process + GO:0010701 + positive regulation of norepinephrine secretion + + + + Any process that increases the frequency, rate or extent of the regulated release of norepinephrine. + GOC:dph + GOC:tb + - + - + - - + + - - - - - - - - - negative regulation of feeding behavior + Any process that modulates the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix. + regulation of collagen breakdown + regulation of collagen catabolism + regulation of collagen degradation + biological_process + GO:0010710 + regulation of collagen catabolic process + + + + Any process that modulates the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix. + GOC:BHF + GOC:dph + GOC:tb + + + + + regulation of collagen breakdown + GOC:dph + GOC:tb + + + + + regulation of collagen catabolism + GOC:dph + GOC:tb + + + + + regulation of collagen degradation + GOC:dph + GOC:tb + - + - + - - + + + + + + + Any process that decreases the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix. + down regulation of collagen catabolic process + down-regulation of collagen catabolic process + downregulation of collagen catabolic process + negative regulation of collagen breakdown + negative regulation of collagen catabolism + negative regulation of collagen degradation + inhibition of collagen catabolic process + biological_process + GO:0010711 + negative regulation of collagen catabolic process + + + + + Any process that decreases the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix. + GOC:BHF + GOC:dph + GOC:tb + + + + + down regulation of collagen catabolic process + GOC:dph + GOC:tb + + + + + down-regulation of collagen catabolic process + GOC:dph + GOC:tb + + + + + downregulation of collagen catabolic process + GOC:dph + GOC:tb + + + + + negative regulation of collagen breakdown + GOC:dph + GOC:tb + + + + + negative regulation of collagen catabolism + GOC:dph + GOC:tb + + + + + negative regulation of collagen degradation + GOC:dph + GOC:tb + + + + + inhibition of collagen catabolic process + GOC:dph + GOC:tb + + + + + + + + + + + + + + - - - - - - - - - positive regulation of feeding behavior + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. + regulation of collagen metabolism + biological_process + GO:0010712 + regulation of collagen metabolic process + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. + GOC:dph + GOC:tb + + + + + regulation of collagen metabolism + GOC:dph + GOC:tb + - + - + - + - - - - - - - - - negative regulation of signaling receptor activity + Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. + biological_process + GO:0010713 + negative regulation of collagen metabolic process + + + + Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. + GOC:dph + GOC:tb + - + - + - + - - - - - - - - - positive regulation of signaling receptor activity + Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. + positive regulation of collagen metabolism + biological_process + GO:0010714 + positive regulation of collagen metabolic process + + + + Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. + GOC:dph + GOC:tb + + + + + positive regulation of collagen metabolism + GOC:dph + GOC:tb + - + - + - + - - - - - - - - regulation of defecation + Any process that modulates the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. + biological_process + GO:0010717 + regulation of epithelial to mesenchymal transition + + + + Any process that modulates the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. + GOC:BHF + GOC:dph + GOC:tb + - + - + - - + + - - - - - + + - negative regulation of defecation + Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. + biological_process + GO:0010718 + positive regulation of epithelial to mesenchymal transition - - + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. + GOC:BHF + GOC:dph + GOC:tb + + - - + + + - - + + - - - - - + + - positive regulation of defecation + Any process that decreases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. + biological_process + GO:0010719 + negative regulation of epithelial to mesenchymal transition + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that decreases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. + GOC:BHF + GOC:dph + GOC:tb + - + - + - - + + - - - - - - - - regulation of mesoderm development + + + Any process that increases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. + biological_process + GO:0010720 + positive regulation of cell development + + + + Any process that increases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. + GOC:BHF + GOC:dph + GOC:tb + - + - + - + - - - - - - - - - negative regulation of mesoderm development + + + Any process that decreases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. + biological_process + GO:0010721 + negative regulation of cell development + + + + Any process that decreases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. + GOC:BHF + GOC:dph + GOC:tb + - + - + - + - - + + - - - - - - - - - positive regulation of mesoderm development + + Cell migration that is accomplished by extension and retraction of a fibroblast pseudopodium. A fibroblast is a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. + fibroblast cell migration + biological_process + GO:0010761 + fibroblast migration + + + + Cell migration that is accomplished by extension and retraction of a fibroblast pseudopodium. A fibroblast is a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules. + GOC:BHF + GOC:dph + GOC:tb + + + + + fibroblast cell migration + GOC:dph + - + - + - + - - - - - - - - regulation of ectoderm development + Any process that modulates the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium. + regulation of fibroblast cell migration + biological_process + GO:0010762 + regulation of fibroblast migration + + + + Any process that modulates the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium. + GOC:dph + GOC:tb + + + + + regulation of fibroblast cell migration + GOC:dph + - + - + + + + + + + + + + + + + Any process that increases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium. + positive regulation of fibroblast cell migration + biological_process + GO:0010763 + positive regulation of fibroblast migration + + + + + Any process that increases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium. + GOC:BHF + GOC:dph + GOC:tb + + + + + positive regulation of fibroblast cell migration + GOC:dph + + + + + + + - + - - - - - - - - - negative regulation of ectoderm development + Any process that decreases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium. + negative regulation of fibroblast cell migration + biological_process + GO:0010764 + negative regulation of fibroblast migration + + + + Any process that decreases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium. + GOC:dph + GOC:tb + + + + + negative regulation of fibroblast cell migration + GOC:dph + - + - + - + - - - - - - - - - positive regulation of ectoderm development + Any process that increases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + biological_process + GO:0010765 + positive regulation of sodium ion transport + + + + Any process that increases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:dph + GOC:tb + - + - + - + - - - - - - - - - negative regulation of gastrulation + Any process that decreases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + biological_process + GO:0010766 + negative regulation of sodium ion transport + + + + Any process that decreases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:dph + GOC:tb + - + - + - - + + - - - - - - - - - positive regulation of gastrulation + Any process that modulates the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. + biological_process + GO:0010769 + regulation of cell morphogenesis involved in differentiation + + + + Any process that modulates the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. + GOC:dph + GOC:tb + - + - + - - + + - - - - - - - - - - regulation of thyroid hormone generation + + Any process that increases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. + biological_process + GO:0010770 + positive regulation of cell morphogenesis involved in differentiation + + + + Any process that increases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. + GOC:dph + GOC:tb + - + - + - + - - - - - - - - - - - negative regulation of thyroid hormone generation + + Any process that decreases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. + biological_process + GO:0010771 + negative regulation of cell morphogenesis involved in differentiation + + + + Any process that decreases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. + GOC:dph + GOC:tb + - + - + - + - - + + - - - - - - - - - - - positive regulation of thyroid hormone generation + + + The chemical reactions and pathways resulting in the breakdown of the peptide calcitonin. + biological_process + GO:0010816 + calcitonin catabolic process + + + + The chemical reactions and pathways resulting in the breakdown of the peptide calcitonin. + GOC:BHF + GOC:rl + - + - + - - + + - - - - - - - - regulation of grooming behavior + Any process that modulates the levels of hormone within an organism or a tissue. A hormone is any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. + biological_process + GO:0010817 + regulation of hormone levels + + + + Any process that modulates the levels of hormone within an organism or a tissue. A hormone is any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. + GOC:BHF + GOC:dph + GOC:tb + - + - + - + - - - - - - - - - regulation of parathyroid hormone secretion + Any process that modulates the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. + biological_process + GO:0010830 + regulation of myotube differentiation + + + + Any process that modulates the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. + GOC:dph + GOC:tb + - + - + - - + + - - - - - - - - - - negative regulation of parathyroid hormone secretion + Any process that activates, maintains or increases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. + biological_process + GO:0010831 + positive regulation of myotube differentiation + + + + Any process that activates, maintains or increases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. + GOC:dph + GOC:tb + - + - + - - + + - - - - - - - - - - positive regulation of parathyroid hormone secretion + Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. + biological_process + GO:0010832 + negative regulation of myotube differentiation + + + + Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. + GOC:dph + GOC:tb + - + - + - + - - - - - - - - - - regulation of steroid hormone secretion + + Any process that modulates the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population. + biological_process + GO:0010837 + regulation of keratinocyte proliferation + + + + Any process that modulates the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population. + GOC:dph + GOC:tb + - + - + - - + + - - - - - - - - - - - negative regulation of steroid hormone secretion + + + Any process that increases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population. + biological_process + GO:0010838 + positive regulation of keratinocyte proliferation + + + + Any process that increases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population. + GOC:dph + GOC:tb + - + - + - - + + - - - - - - - - - - - positive regulation of steroid hormone secretion + + + Any process that decreases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population. + biological_process + GO:0010839 + negative regulation of keratinocyte proliferation + + + + Any process that decreases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population. + GOC:dph + GOC:tb + - + - + - + - - + + - + + - - + + - regulation of corticosteroid hormone secretion - + + + + + + + The process in which the vertebrate retina is organized into three laminae: the outer nuclear layer (ONL), which contains photoreceptor nuclei; the inner nuclear layer (INL), which contains amacrine, bipolar and horizontal cells; and the retinal ganglion cell (RGC) layer. Between the inner and outer nuclear layers, the outer plexiform layer (OPL) contains connections between the photoreceptors and bipolar and horizontal cells. The inner plexiform layer (IPL) is positioned between the INL and the ganglion cell layer and contains the dendrites of RGCs and processes of bipolar and amacrine cells. Spanning all layers of the retina are the radially oriented Mueller glia. + retinal lamination + retinal layer formation + biological_process + GO:0010842 + retina layer formation + + + + + The process in which the vertebrate retina is organized into three laminae: the outer nuclear layer (ONL), which contains photoreceptor nuclei; the inner nuclear layer (INL), which contains amacrine, bipolar and horizontal cells; and the retinal ganglion cell (RGC) layer. Between the inner and outer nuclear layers, the outer plexiform layer (OPL) contains connections between the photoreceptors and bipolar and horizontal cells. The inner plexiform layer (IPL) is positioned between the INL and the ganglion cell layer and contains the dendrites of RGCs and processes of bipolar and amacrine cells. Spanning all layers of the retina are the radially oriented Mueller glia. + GOC:ascb_2009 + GOC:dph + GOC:tb + PMID:1270266 + + + + + retinal lamination + GOC:dph + GOC:tb + + + + + retinal layer formation + GOC:dph + GOC:tb + - + - + - + - - + + - - - - - - - - - negative regulation of corticosteroid hormone secretion + + Any process in which a lipid is transported to, or maintained in, a specific location. + lipid localisation + biological_process + GO:0010876 + lipid localization + + + + Any process in which a lipid is transported to, or maintained in, a specific location. + GOC:BHF + GOC:dph + GOC:tb + + + + + lipid localisation + GOC:mah + - + - + - + - - - - - - - - - positive regulation of corticosteroid hormone secretion + + + + Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. + biological_process + GO:0010893 + positive regulation of steroid biosynthetic process + + + + Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. + GOC:tb + - + - + - - + + - - - - - - - - regulation of mineralocorticoid secretion + + + + Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. + biological_process + GO:0010894 + negative regulation of steroid biosynthetic process + + + + Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. + GOC:BHF + GOC:tb + - + - + - - + + - - - - - - - - - negative regulation of mineralocorticoid secretion + + Any process that modulates the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. + regulation of glucose metabolism + biological_process + GO:0010906 + regulation of glucose metabolic process + + + + Any process that modulates the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. + GOC:BHF + GOC:tb + + + + + regulation of glucose metabolism + GOC:tb + - + - + - + - - - - - - - - - positive regulation of mineralocorticoid secretion + + + Any process that increases the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. + positive regulation of glucose metabolism + biological_process + GO:0010907 + positive regulation of glucose metabolic process + + + + Any process that increases the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. + GOC:BHF + GOC:tb + + + + + positive regulation of glucose metabolism + GOC:tb + - + - + - + - - + + - + + - - + + - regulation of aldosterone secretion + The cellular component assembly that is part of the initial shaping of the component during its developmental progression. + biological_process + GO:0010927 + cellular component assembly involved in morphogenesis + + + + The cellular component assembly that is part of the initial shaping of the component during its developmental progression. + GOC:dph + GOC:tb + - + - + - + - - - - - - - - - negative regulation of aldosterone secretion + + Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. + tb + 2009-04-27T09:53:22Z + biological_process + GO:0010948 + negative regulation of cell cycle process + + + + Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. + GOC:dph + GOC:tb + - + - + - - + + - - - - - - - - - positive regulation of aldosterone secretion + Any process that modulates the frequency, rate, or extent of metal ion transport. Metal ion transport is the directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + tb + 2009-05-06T11:40:55Z + biological_process + GO:0010959 + regulation of metal ion transport + + + + Any process that modulates the frequency, rate, or extent of metal ion transport. Metal ion transport is the directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:dph + GOC:tb + - + - + - + - - - - - - - - - regulation of progesterone secretion + + + + Any process that modulates the rate, frequency, or extent of glucan biosynthesis. Glucan biosynthetic processes are the chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues. + tb + 2009-05-11T12:17:53Z + biological_process + GO:0010962 + regulation of glucan biosynthetic process + + + + Any process that modulates the rate, frequency, or extent of glucan biosynthesis. Glucan biosynthetic processes are the chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues. + GOC:dph + GOC:tb + - + - + - - + + - - - - - + + - negative regulation of progesterone secretion + Any process that modulates the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell. + tb + 2009-05-20T11:51:21Z + biological_process + GO:0010968 + regulation of microtubule nucleation + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell. + GOC:dph + GOC:tb + - + - + - + - - + + - - - - - - - - - - positive regulation of progesterone secretion + + + The movement of organelles or other particles from one location in the cell to another along microtubules, driven by motor activity. + tb + 2009-05-27T10:56:08Z + microtubule-based transport + establishment of localization by movement along microtubule + movement along microtubule + biological_process + GO:0010970 + transport along microtubule + + + + The movement of organelles or other particles from one location in the cell to another along microtubules, driven by motor activity. + GOC:dph + GOC:mah + GOC:tb + + + + + establishment of localization by movement along microtubule + GOC:dph + - + - + - + - - - - - - - + Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). + tb + 2009-06-01T10:44:45Z + regulation of neurite biosynthesis + regulation of neurite development + regulation of neurite formation + regulation of neurite growth + biological_process + GO:0010975 + regulation of neuron projection development + + + + + Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). + GOC:dph + GOC:tb + + + + + regulation of neurite biosynthesis + GOC:mah + + + + + regulation of neurite development + GOC:mah + + + + + regulation of neurite formation + GOC:mah + + + + + regulation of neurite growth + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). + tb + 2009-06-01T10:46:44Z + positive regulation of neurite biosynthesis + positive regulation of neurite development + positive regulation of neurite formation + positive regulation of neurite growth + biological_process + GO:0010976 + positive regulation of neuron projection development + + + + + Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). + GOC:dph + GOC:tb + + + + + positive regulation of neurite biosynthesis + GOC:mah + + + + + positive regulation of neurite development + GOC:mah + + + + + positive regulation of neurite formation + GOC:mah + + + + + positive regulation of neurite growth + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). + tb + 2009-06-01T10:47:42Z + negative regulation of neurite biosynthesis + negative regulation of neurite development + negative regulation of neurite formation + negative regulation of neurite growth + biological_process + growth cone collapse + GO:0010977 + negative regulation of neuron projection development + + + + + Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). + GOC:dph + GOC:tb + + + + + negative regulation of neurite biosynthesis + GOC:mah + + + + + negative regulation of neurite development + GOC:mah + + + + + negative regulation of neurite formation + GOC:mah + + + + + negative regulation of neurite growth + GOC:mah + + + + + growth cone collapse + GOC:pr + + + + + + + + + + + + - regulation of renal water transport + + + + + + + + + + + + + A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles. + Wikipedia:Endomembrane_system + cellular_component + GO:0012505 + + + + endomembrane system + + + + A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles. + GOC:lh + - + - + + + + + + + + + + + + + The lipid bilayer surrounding any membrane-bounded vesicle in the cell. + NIF_Subcellular:sao1153182838 + cellular_component + GO:0012506 + vesicle membrane + + + + + The lipid bilayer surrounding any membrane-bounded vesicle in the cell. + GOC:mah + GOC:vesicle + + + + + + + + + + + + + + + + + + + + + + + + + + The process aimed at the progression of an astrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function. + astrocyte cell development + biological_process + GO:0014002 + astrocyte development + + + + + The process aimed at the progression of an astrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function. + GOC:dgh + GOC:ef + + + + + + + + + + + + + + + + + + + + + + + + + + The process aimed at the progression of an oligodendrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An oligodendrocyte is a type of glial cell involved in myelinating the axons in the central nervous system. + oligodendrocyte cell development + biological_process + GO:0014003 + oligodendrocyte development + + + + + The process aimed at the progression of an oligodendrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An oligodendrocyte is a type of glial cell involved in myelinating the axons in the central nervous system. + GOC:dgh + GOC:ef + + + + + + + + + + + + + + + + + + + + + + + + + + The multiplication or reproduction of glial cells by cell division, resulting in the expansion of their population. Glial cells exist throughout the nervous system, and include Schwann cells, astrocytes, and oligodendrocytes among others. + glia proliferation + biological_process + GO:0014009 + glial cell proliferation + + + + + The multiplication or reproduction of glial cells by cell division, resulting in the expansion of their population. Glial cells exist throughout the nervous system, and include Schwann cells, astrocytes, and oligodendrocytes among others. + GOC:ef + ISBN:0878932585 + + + + + + + + + + + + + + + + + + + + The multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system. + biological_process + GO:0014010 + Schwann cell proliferation + + + + + The multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system. + GOC:ef + ISBN:0878932585 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of gliogenesis, the formation of mature glia. + biological_process + GO:0014013 + regulation of gliogenesis + + + + + Any process that modulates the frequency, rate or extent of gliogenesis, the formation of mature glia. + GOC:ef + + + + + + + - + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of gliogenesis, the formation of mature glia. + down regulation of gliogenesis + down-regulation of gliogenesis + downregulation of gliogenesis + inhibition of gliogenesis + biological_process + GO:0014014 + negative regulation of gliogenesis + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of gliogenesis, the formation of mature glia. + GOC:ef + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of gliogenesis, the formation of mature glia. + up regulation of gliogenesis + up-regulation of gliogenesis + upregulation of gliogenesis + activation of gliogenesis + stimulation of gliogenesis + biological_process + GO:0014015 + positive regulation of gliogenesis + + + + + Any process that activates or increases the frequency, rate or extent of gliogenesis, the formation of mature glia. + GOC:ef + + + + + + + + + + + + + + - - - - - + + - negative regulation of renal water transport + The process in which a relatively unspecialized cell acquires specialized features of a neuroblast. There are at least four stages through which the pluripotent cells of epiblast or blastula become neuroblasts. + biological_process + GO:0014016 + neuroblast differentiation + + + + The process in which a relatively unspecialized cell acquires specialized features of a neuroblast. There are at least four stages through which the pluripotent cells of epiblast or blastula become neuroblasts. + GOC:ef + ISBN:0878932585 + - + - + + + + + + + + + + + + + + + + + + + The process aimed at the progression of a neuroblast over time, from initial commitment of the cell to a specific state, to the mature neuroblast. It does not include processes where the neuroblast turns into a glial cell or a neuron. + biological_process + GO:0014019 + neuroblast development + + + + + The process aimed at the progression of a neuroblast over time, from initial commitment of the cell to a specific state, to the mature neuroblast. It does not include processes where the neuroblast turns into a glial cell or a neuron. + GOC:ef + ISBN:0878932585 + + + + + + + + + + + + + + + The formation of the neural tube from an epithelial cell sheet (the neuroepithelium or neural plate). In primary neurulation, the cells surrounding the neural plate direct the neural plate cells to proliferate, invaginate, and pinch off from the surface to form a hollow epithelial tube. Primary neurulation is the typical mechanism of formation of the anterior neural tube. + GO:0014024 + primary neural tube morphogenesis + primary neurulation + biological_process + neural rod cavitation + GO:0014020 + primary neural tube formation + + + + + The formation of the neural tube from an epithelial cell sheet (the neuroepithelium or neural plate). In primary neurulation, the cells surrounding the neural plate direct the neural plate cells to proliferate, invaginate, and pinch off from the surface to form a hollow epithelial tube. Primary neurulation is the typical mechanism of formation of the anterior neural tube. + GOC:ef + ISBN:0878932585 + PMID:15327780 + + + + + primary neural tube morphogenesis + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The formation of a solid rod of neurectoderm derived from the neural keel. The neural rod is roughly circular in cross section. Neural rod formation occurs during primary neurulation in teleosts. + biological_process + GO:0014023 + neural rod formation + + + + + The formation of a solid rod of neurectoderm derived from the neural keel. The neural rod is roughly circular in cross section. Neural rod formation occurs during primary neurulation in teleosts. + GOC:dh + GOC:ef + + + + + + + + + + + + + + + + + + + + + + + + + + + The formation of a thickened region of the neurectoderm that is roughly triangular in cross section. The neural keel develops from the neural plate and develops into the neural rod. Neural keel formation occurs during primary neurulation in teleosts. + biological_process + GO:0014025 + neural keel formation + + + + + The formation of a thickened region of the neurectoderm that is roughly triangular in cross section. The neural keel develops from the neural plate and develops into the neural rod. Neural keel formation occurs during primary neurulation in teleosts. + GOC:dh + GOC:ef + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The formation of the notochord from the chordamesoderm. The notochord is composed of large cells packed within a firm connective tissue sheath and is found in all chordates at the ventral surface of the neural tube. In vertebrates, the notochord contributes to the vertebral column. + biological_process + GO:0014028 + notochord formation + + + + + The formation of the notochord from the chordamesoderm. The notochord is composed of large cells packed within a firm connective tissue sheath and is found in all chordates at the ventral surface of the neural tube. In vertebrates, the notochord contributes to the vertebral column. + GOC:dh + GOC:ef + + + + + + + + + + + + + + + + + + + + + + + + + + The formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes. + biological_process + GO:0014029 + neural crest formation + + + + + The formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes. + GOC:dh + GOC:ef + + + + + + + + + + + + + + + + + + + + + + + + + The process aimed at the progression of a mesenchymal cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. + biological_process + GO:0014031 + mesenchymal cell development + + + + + The process aimed at the progression of a mesenchymal cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. + GOC:dh + GOC:ef + + + + + + + + + + + + + + + + + + + + + + + + + The process aimed at the progression of a neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. + biological_process + GO:0014032 + neural crest cell development + + + + + The process aimed at the progression of a neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. + GOC:dh + GOC:ef + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of a neural crest cell. + biological_process + GO:0014033 + neural crest cell differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized features of a neural crest cell. + GOC:dh + GOC:ef + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires the specialized features of a Schwann cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function. + biological_process + GO:0014037 + Schwann cell differentiation + + + + + The process in which a relatively unspecialized cell acquires the specialized features of a Schwann cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function. + GOC:ef + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of Schwann cell differentiation. + biological_process + GO:0014038 + regulation of Schwann cell differentiation + + + + + Any process that modulates the frequency, rate or extent of Schwann cell differentiation. + GOC:ef + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of Schwann cell differentiation. + down regulation of Schwann cell differentiation + down-regulation of Schwann cell differentiation + downregulation of Schwann cell differentiation + inhibition of Schwann cell differentiation + biological_process + GO:0014039 + negative regulation of Schwann cell differentiation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of Schwann cell differentiation. + GOC:ef + + + + + + + - + + + + + + Any process that activates or increases the frequency, rate or extent of Schwann cell differentiation. + up regulation of Schwann cell differentiation + up-regulation of Schwann cell differentiation + upregulation of Schwann cell differentiation + activation of Schwann cell differentiation + stimulation of Schwann cell differentiation + biological_process + GO:0014040 + positive regulation of Schwann cell differentiation + + + + + Any process that activates or increases the frequency, rate or extent of Schwann cell differentiation. + GOC:ef + + + + + + + + + + + + + + - - - - - + + - positive regulation of renal water transport + Any process that modulates the frequency, rate or extent of neuron maturation, the process leading to the attainment of the full functional capacity of a neuron. This process is independent of morphogenetic change. + biological_process + GO:0014041 + regulation of neuron maturation + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate or extent of neuron maturation, the process leading to the attainment of the full functional capacity of a neuron. This process is independent of morphogenetic change. + GOC:ef + - + - - preceded by - - - precedes - - - bearer of - - - participates_in - - - bounding layer of - - - immediately_preceded_by - - - overlaps - - - has component - - - capable of - - - capable of part of - - - adjacent to - - - starts with - - - ends with - - - output of - - - produces - - - produced by - + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of neuron maturation. + up regulation of neuron maturation + up-regulation of neuron maturation + upregulation of neuron maturation + activation of neuron maturation + stimulation of neuron maturation + biological_process + GO:0014042 + positive regulation of neuron maturation + + + + + Any process that activates or increases the frequency, rate or extent of neuron maturation. + GOC:ef + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of neuron maturation. + down regulation of neuron maturation + down-regulation of neuron maturation + downregulation of neuron maturation + inhibition of neuron maturation + biological_process + GO:0014043 + negative regulation of neuron maturation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of neuron maturation. + GOC:ef + + + + + + + + + + + + + + + + + + + + + + + + + + The process aimed at the progression of a Schwann cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function. + biological_process + GO:0014044 + Schwann cell development + + + + + The process aimed at the progression of a Schwann cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function. + GOC:dgh + GOC:ef + + + + + + + + + + + + + + + + + + + + The regulated release of dopamine by a cell. Dopamine is a catecholamine and a precursor of adrenaline and noradrenaline. It acts as a neurotransmitter in the central nervous system but it is also produced peripherally and acts as a hormone. + biological_process + GO:0014046 + dopamine secretion + + + + + The regulated release of dopamine by a cell. Dopamine is a catecholamine and a precursor of adrenaline and noradrenaline. It acts as a neurotransmitter in the central nervous system but it is also produced peripherally and acts as a hormone. + GOC:ef + + + + + + + + + + + + + + + + + + + + + The controlled release of glutamate by a cell. The glutamate is the most abundant excitatory neurotransmitter in the nervous system. + biological_process + GO:0014047 + glutamate secretion + + + + + The controlled release of glutamate by a cell. The glutamate is the most abundant excitatory neurotransmitter in the nervous system. + GOC:ef + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the controlled release of glutamate. + biological_process + GO:0014048 + regulation of glutamate secretion + + + + + Any process that modulates the frequency, rate or extent of the controlled release of glutamate. + GOC:ef + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the controlled release of glutamate. + up regulation of glutamate secretion + up-regulation of glutamate secretion + upregulation of glutamate secretion + activation of glutamate secretion + stimulation of glutamate secretion + biological_process + GO:0014049 + positive regulation of glutamate secretion + + + + + Any process that activates or increases the frequency, rate or extent of the controlled release of glutamate. + GOC:ef + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of glutamate. + down regulation of glutamate secretion + down-regulation of glutamate secretion + downregulation of glutamate secretion + inhibition of glutamate secretion + biological_process + GO:0014050 + negative regulation of glutamate secretion + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of glutamate. + GOC:ef + + + + + + + + + + + + + + + + + + + + The regulated release of gamma-aminobutyric acid by a cell or a tissue. The gamma-aminobutyric acid is the principal inhibitory neurotransmitter in the brain but is also found in several extraneural tissues. + GABA secretion + biological_process + GO:0014051 + gamma-aminobutyric acid secretion + + + + + The regulated release of gamma-aminobutyric acid by a cell or a tissue. The gamma-aminobutyric acid is the principal inhibitory neurotransmitter in the brain but is also found in several extraneural tissues. + GOC:ef + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the regulated release of gamma-aminobutyric acid. + regulation of GABA secretion + biological_process + GO:0014052 + regulation of gamma-aminobutyric acid secretion + + + + + Any process that modulates the frequency, rate or extent of the regulated release of gamma-aminobutyric acid. + GOC:ef + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of gamma-aminobutyric acid. + down regulation of gamma-aminobutyric acid secretion + down-regulation of gamma-aminobutyric acid secretion + downregulation of gamma-aminobutyric acid secretion + negative regulation of GABA secretion + inhibition of gamma-aminobutyric acid secretion + biological_process + GO:0014053 + negative regulation of gamma-aminobutyric acid secretion + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of gamma-aminobutyric acid. + GOC:ef + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the regulated release of gamma-aminobutyric acid. + positive regulation of GABA secretion + up regulation of gamma-aminobutyric acid secretion + up-regulation of gamma-aminobutyric acid secretion + upregulation of gamma-aminobutyric acid secretion + activation of gamma-aminobutyric acid secretion + stimulation of gamma-aminobutyric acid secretion + biological_process + GO:0014054 + positive regulation of gamma-aminobutyric acid secretion + + + + + Any process that activates or increases the frequency, rate or extent of the regulated release of gamma-aminobutyric acid. + GOC:ef + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the regulated release of dopamine. + biological_process + GO:0014059 + regulation of dopamine secretion + + + + + Any process that modulates the frequency, rate or extent of the regulated release of dopamine. + GOC:ef + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the regulated release of norepinephrine. + regulation of noradrenaline secretion + biological_process + GO:0014061 + regulation of norepinephrine secretion + + + + + Any process that modulates the frequency, rate or extent of the regulated release of norepinephrine. + GOC:ef + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the regulated release of serotonin. + biological_process + regulation of serotonin release + GO:0014062 + regulation of serotonin secretion + + + + + Any process that modulates the frequency, rate or extent of the regulated release of serotonin. + GOC:ef + + + + + regulation of serotonin release + GOC:tb + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of serotonin. + down regulation of serotonin secretion + down-regulation of serotonin secretion + downregulation of serotonin secretion + inhibition of serotonin secretion + biological_process + positive regulation of serotonin release + GO:0014063 + negative regulation of serotonin secretion + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of serotonin. + GOC:ef + + + + + positive regulation of serotonin release + GOC:tb + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the regulated release of serotonin. + up regulation of serotonin secretion + up-regulation of serotonin secretion + upregulation of serotonin secretion + activation of serotonin secretion + stimulation of serotonin secretion + biological_process + positive regulation of serotonin release + GO:0014064 + positive regulation of serotonin secretion + + + + + Any process that activates or increases the frequency, rate or extent of the regulated release of serotonin. + GOC:ef + + + + + positive regulation of serotonin release + GOC:tb + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus. + response to organic cyclic substance + biological_process + GO:0014070 + response to organic cyclic compound + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus. + GOC:ef + + + + + response to organic cyclic substance + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups. + response to amine stimulus + biological_process + GO:0014075 + response to amine + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups. + GOC:ef + + + + + response to amine stimulus + GOC:dos + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a striated muscle over time, from its formation to the mature structure. Striated muscle contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. Skeletal muscle myoblasts fuse to form myotubes and eventually multinucleated muscle fibers. The fusion of cardiac cells is very rare and can only form binucleate cells. + biological_process + GO:0014706 + striated muscle tissue development + + + + + The process whose specific outcome is the progression of a striated muscle over time, from its formation to the mature structure. Striated muscle contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. Skeletal muscle myoblasts fuse to form myotubes and eventually multinucleated muscle fibers. The fusion of cardiac cells is very rare and can only form binucleate cells. + CL:0000737 + GOC:dph + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure. The branchiomeric muscle is derived from cranial mesoderm and controls facial expression, pharyngeal and laryngeal function, operating the jaw. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. Branchiomeric muscles of mammals correspond to the gill musculature of fish. + biological_process + GO:0014707 + branchiomeric skeletal muscle development + + + + + The process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure. The branchiomeric muscle is derived from cranial mesoderm and controls facial expression, pharyngeal and laryngeal function, operating the jaw. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. Branchiomeric muscles of mammals correspond to the gill musculature of fish. + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of somitomeric trunk muscle development. + biological_process + GO:0014708 + regulation of somitomeric trunk muscle development + + + + + Any process that modulates the frequency, rate or extent of somitomeric trunk muscle development. + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + Any process that activates, maintains or increases the frequency, rate or extent of somitomeric trunk muscle development. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. + biological_process + GO:0014709 + positive regulation of somitomeric trunk muscle development + + + + + Any process that activates, maintains or increases the frequency, rate or extent of somitomeric trunk muscle development. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of somitomeric trunk muscle development. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. + biological_process + GO:0014710 + negative regulation of somitomeric trunk muscle development + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of somitomeric trunk muscle development. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure. + biological_process + GO:0014711 + regulation of branchiomeric skeletal muscle development + + + + + Any process that modulates the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure. + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + Any process that activates, maintains or increases the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure. + biological_process + GO:0014712 + positive regulation of branchiomeric skeletal muscle development + + + + + Any process that activates, maintains or increases the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure. + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure. + biological_process + GO:0014713 + negative regulation of branchiomeric skeletal muscle development + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure. + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. + biological_process + GO:0014725 + regulation of extraocular skeletal muscle development + + + + + Any process that modulates the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. + biological_process + GO:0014726 + negative regulation of extraocular skeletal muscle development + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + Any process that activates, maintains or increases the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. + biological_process + GO:0014727 + positive regulation of extraocular skeletal muscle development + + + + + Any process that activates, maintains or increases the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + Any process in which skeletal muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities. + biological_process + regulation of skeletal muscle plasticity + GO:0014733 + regulation of skeletal muscle adaptation + + + + + Any process in which skeletal muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities. + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + + + The enlargement or overgrowth of all or part of an organ due to an increase in size (not length) of individual muscle fibers without cell division. In the case of skeletal muscle cells this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils. + biological_process + GO:0014734 + skeletal muscle hypertrophy + + + + + The enlargement or overgrowth of all or part of an organ due to an increase in size (not length) of individual muscle fibers without cell division. In the case of skeletal muscle cells this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils. + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hypertrophy. + biological_process + GO:0014741 + negative regulation of muscle hypertrophy + + + + + Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hypertrophy. + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of muscle hypertrophy. + biological_process + GO:0014742 + positive regulation of muscle hypertrophy + + + + + Any process that activates or increases the frequency, rate or extent of muscle hypertrophy. + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of muscle hypertrophy. + biological_process + GO:0014743 + regulation of muscle hypertrophy + + + + + Any process that modulates the frequency, rate or extent of muscle hypertrophy. + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of muscle adaptation. + biological_process + positive regulation of muscle plasticity + GO:0014744 + positive regulation of muscle adaptation + + + + + Any process that activates or increases the frequency, rate or extent of muscle adaptation. + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle adaptation. + biological_process + negative regulation of muscle plasticity + GO:0014745 + negative regulation of muscle adaptation + + + + + Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle adaptation. + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + + Any process in which smooth muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities. + biological_process + smooth muscle plasticity + GO:0014805 + smooth muscle adaptation + + + + + Any process in which smooth muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities. + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of somitogenesis. + biological_process + GO:0014807 + regulation of somitogenesis + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate or extent of somitogenesis. + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + + The orderly movement of a muscle cell from one site to another, often during the development of a multicellular organism. + biological_process + GO:0014812 + muscle cell migration + + + + + The orderly movement of a muscle cell from one site to another, often during the development of a multicellular organism. + CL:0000187 + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of skeletal muscle contraction. + biological_process + GO:0014819 + regulation of skeletal muscle contraction + + + + + Any process that modulates the frequency, rate or extent of skeletal muscle contraction. + GOC:ef + GOC:mtg_muscle + + + + + + + + + A process in which force is generated within phasic smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the phasic smooth muscle, the muscle contraction occurs without an ordered sarcomeric structure. Phasic smooth muscle contraction occurs in a series of discrete contractions and relaxations. + biological_process + GO:0014821 + phasic smooth muscle contraction + + + + + A process in which force is generated within phasic smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the phasic smooth muscle, the muscle contraction occurs without an ordered sarcomeric structure. Phasic smooth muscle contraction occurs in a series of discrete contractions and relaxations. + GOC:mtg_muscle + + + + + + + + + + A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the intestine. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The intestine is the section of the alimentary canal from the stomach to the anal canal. It includes the large intestine and small intestine. + biological_process + GO:0014827 + intestine smooth muscle contraction + + + + + A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the intestine. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The intestine is the section of the alimentary canal from the stomach to the anal canal. It includes the large intestine and small intestine. + GOC:mtg_muscle + MA:0001539 + MSH:D007422 + + + + + + + + + A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the gastro-intestinal system. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The gastro-intestinal system generally refers to the digestive structures stretching from the mouth to anus, but does not include the accessory glandular organs (liver, pancreas and biliary tract). + biological_process + GO:0014831 + gastro-intestinal system smooth muscle contraction + + + + + A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the gastro-intestinal system. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The gastro-intestinal system generally refers to the digestive structures stretching from the mouth to anus, but does not include the accessory glandular organs (liver, pancreas and biliary tract). + GOC:mtg_muscle + MA:0001523 + MSH:D041981 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary bladder. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary bladder is a musculomembranous sac along the urinary tract. + + biological_process + GO:0014832 + urinary bladder smooth muscle contraction + + + + + A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary bladder. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary bladder is a musculomembranous sac along the urinary tract. + GOC:mr + GOC:mtg_muscle + PMID:11768524 + PMID:18276178 + PMID:538956 + + + + + + + + + A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary tract. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary tract consists of organs of the body that produce and discharge urine. These include the kidneys, ureters, bladder, and urethra. + biological_process + GO:0014848 + urinary tract smooth muscle contraction + + + + + A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary tract. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary tract consists of organs of the body that produce and discharge urine. These include the kidneys, ureters, bladder, and urethra. + GOC:ef + GOC:mtg_muscle + MA:0000325 + MSH:D014551 + + + + + + + + + + A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the ureter. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder. + biological_process + GO:0014849 + ureter smooth muscle contraction + + + + + A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the ureter. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder. + GOC:mtg_muscle + MA:0000378 + + + + + + + + + + + + + + + + + + + + The multiplication or reproduction of striated muscle cells, resulting in the expansion of a cell population. Striated muscles contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. + biological_process + GO:0014855 + striated muscle cell proliferation + + + + + The multiplication or reproduction of striated muscle cells, resulting in the expansion of a cell population. Striated muscles contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. + CL:0000737 + GOC:ef + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + + The multiplication or reproduction of skeletal muscle cells, resulting in the expansion of a cell population. + biological_process + GO:0014856 + skeletal muscle cell proliferation + + + + + The multiplication or reproduction of skeletal muscle cells, resulting in the expansion of a cell population. + CL:0000188 + GOC:ef + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of skeletal muscle cell proliferation. + biological_process + GO:0014857 + regulation of skeletal muscle cell proliferation + + + + + Any process that modulates the frequency, rate or extent of skeletal muscle cell proliferation. + CL:0000188 + GOC:ef + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of skeletal muscle cell proliferation. + biological_process + GO:0014858 + positive regulation of skeletal muscle cell proliferation + + + + + Any process that activates or increases the frequency, rate or extent of skeletal muscle cell proliferation. + CL:0000188 + GOC:ef + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle cell proliferation. + biological_process + GO:0014859 + negative regulation of skeletal muscle cell proliferation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle cell proliferation. + CL:0000188 + GOC:ef + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the skeletal myofibril over time, from its formation to the mature structure. A skeletal myofibril is a myofibril specific to skeletal muscle cells. + biological_process + GO:0014866 + skeletal myofibril assembly + + + + + The process whose specific outcome is the progression of the skeletal myofibril over time, from its formation to the mature structure. A skeletal myofibril is a myofibril specific to skeletal muscle cells. + GOC:ef + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. This occurs as part of the regulation of muscle adaptation. + biological_process + response to stimulus involved in regulation of muscle plasticity + GO:0014874 + response to stimulus involved in regulation of muscle adaptation + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. This occurs as part of the regulation of muscle adaptation. + GOC:ef + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus. This process occurs as part of the regulation of muscle adaptation. + biological_process + response to electrical stimulus involved in regulation of muscle plasticity + GO:0014878 + response to electrical stimulus involved in regulation of muscle adaptation + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus. This process occurs as part of the regulation of muscle adaptation. + GOC:ef + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + The series of events by which an electrical stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation. + biological_process + GO:0014879 + detection of electrical stimulus involved in regulation of muscle adaptation + + + + + The series of events by which an electrical stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation. + GOC:ef + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + + The process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. + biological_process + cardiac muscle plasticity + GO:0014887 + cardiac muscle adaptation + + + + + The process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + + Any process in which striated muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities. + biological_process + striated muscle plasticity + GO:0014888 + striated muscle adaptation + + + + + Any process in which striated muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities. + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + + + The enlargement or overgrowth of all or part of an organ due to an increase in size of its smooth muscle cells without cell division. Physiological hypertrophy is a normal process during development, and can also occur in mature structures on demand. In the uterus, smooth muscle cells undergo hypertrophy during pregnancy. + biological_process + GO:0014895 + smooth muscle hypertrophy + + + + + The enlargement or overgrowth of all or part of an organ due to an increase in size of its smooth muscle cells without cell division. Physiological hypertrophy is a normal process during development, and can also occur in mature structures on demand. In the uterus, smooth muscle cells undergo hypertrophy during pregnancy. + GOC:mtg_muscle + + + + + + + + + + + + + + + The muscle system process that results in enlargement or overgrowth of all or part of a muscle organ due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development (it stops in cardiac muscle after adolescence) and can also be brought on in response to demand. In athletes cardiac and skeletal muscles undergo hypertrophy stimulated by increasing muscle activity on exercise. Smooth muscle cells in the uterus undergo hypertrophy during pregnancy. + Wikipedia:Muscle_hypertrophy + biological_process + GO:0014896 + muscle hypertrophy + + + + + The muscle system process that results in enlargement or overgrowth of all or part of a muscle organ due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development (it stops in cardiac muscle after adolescence) and can also be brought on in response to demand. In athletes cardiac and skeletal muscles undergo hypertrophy stimulated by increasing muscle activity on exercise. Smooth muscle cells in the uterus undergo hypertrophy during pregnancy. + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + + The enlargement or overgrowth of all or part of an organ due to an increase in size of muscle cells without cell division. In the case of striated muscle, this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils. + biological_process + GO:0014897 + striated muscle hypertrophy + + + + + The enlargement or overgrowth of all or part of an organ due to an increase in size of muscle cells without cell division. In the case of striated muscle, this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils. + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. + biological_process + GO:0014902 + myotube differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + + + + + + + The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. + biological_process + GO:0014904 + myotube cell development + + + + + The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + + + + + + + The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. This occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. + biological_process + GO:0014906 + myotube cell development involved in skeletal muscle regeneration + + + + + The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. This occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. This process occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. + biological_process + GO:0014908 + myotube differentiation involved in skeletal muscle regeneration + + + + + The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. This process occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse. + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + + The orderly movement of a smooth muscle cell from one site to another, often during the development of a multicellular organism. + biological_process + GO:0014909 + smooth muscle cell migration + + + + + The orderly movement of a smooth muscle cell from one site to another, often during the development of a multicellular organism. + CL:0000192 + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of smooth muscle cell migration. + biological_process + GO:0014910 + regulation of smooth muscle cell migration + + + + + Any process that modulates the frequency, rate or extent of smooth muscle cell migration. + CL:0000192 + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + Any process that activates, maintains or increases the frequency, rate or extent of smooth muscle cell migration. + biological_process + GO:0014911 + positive regulation of smooth muscle cell migration + + + + + Any process that activates, maintains or increases the frequency, rate or extent of smooth muscle cell migration. + CL:0000192 + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell migration. + biological_process + GO:0014912 + negative regulation of smooth muscle cell migration + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell migration. + CL:0000192 + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + + + + The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GO:0015831 + enzyme transport + biological_process + GO:0015031 + + + + protein transport + + + + + The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:ai + + + + + + + + + The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes. + cellular_component + GO:0015629 + actin cytoskeleton + + + + + The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes. + GOC:jl + ISBN:0395825172 + ISBN:0815316194 + + + + + + + + + The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins. + cellular_component + GO:0015630 + microtubule cytoskeleton + + + + + The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins. + GOC:jl + ISBN:0395825172 + + + + + + + + + Binding to monomeric or multimeric forms of tubulin, including microtubules. + molecular_function + GO:0015631 + tubulin binding + + + + + Binding to monomeric or multimeric forms of tubulin, including microtubules. + GOC:clt + + + + + + + + + The directed movement of substances that are gaseous in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + biological_process + GO:0015669 + + gas transport + + + + + The directed movement of substances that are gaseous in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:ai + + + + + + + + + + + + + + + + + + + + The directed movement of carbon dioxide (CO2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + biological_process + GO:0015670 + carbon dioxide transport + + + + + The directed movement of carbon dioxide (CO2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:ai + + + + + + + + + + + + + + + + + + + + The directed movement of monocarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + biological_process + GO:0015718 + monocarboxylic acid transport + + + + + The directed movement of monocarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:krc + + + + + + + + + + + + + + + + + + + + + + The directed movement of bile acid and bile salts into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + bile acid transport + bile salt transport + biological_process + GO:0015721 + bile acid and bile salt transport + + + + + The directed movement of bile acid and bile salts into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:dph + GOC:krc + PMID:12663868 + PMID:14699511 + + + + + + + + + + + + + + + + + + + + + + + + + The directed movement of polysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. + biological_process + GO:0015774 + polysaccharide transport + + + + + The directed movement of polysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. + GOC:ai + + + + + + + + + The directed movement of acidic amino acids, amino acids with a pH below 7, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + biological_process + GO:0015800 + acidic amino acid transport + + + + + The directed movement of acidic amino acids, amino acids with a pH below 7, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:ai + + + + + + + + + + + + + + + + + + + The directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + 4-aminobutanoate transport + 4-aminobutyrate transport + GABA transport + biological_process + GO:0015812 + See also the biological process term 'neurotransmitter transport ; GO:0006836'. + gamma-aminobutyric acid transport + + + + + The directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:go_curators + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + + The directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + biological_process + GO:0015833 + + peptide transport + + + + + The directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:ai + + + + + + + + + + + + + + + + + + + The directed movement of amines, including polyamines, organic compounds containing one or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + biological_process + amine/polyamine transport + GO:0015837 + + amine transport + + + + + The directed movement of amines, including polyamines, organic compounds containing one or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:ai + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + + The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + biological_process + GO:0015849 + + organic acid transport + + + + + The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + + The directed movement of an organic hydroxy compound (organic alcohol) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. An organic hydroxy compound is an organic compound having at least one hydroxy group attached to a carbon atom. + organic alcohol transport + biological_process + GO:0015850 + organic hydroxy compound transport + + + + + The directed movement of an organic hydroxy compound (organic alcohol) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. An organic hydroxy compound is an organic compound having at least one hydroxy group attached to a carbon atom. + GOC:ai + + + + + + + + + + + + + + + + + + + The directed movement of choline into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Choline (2-hydroxyethyltrimethylammonium) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine. + biological_process + GO:0015871 + choline transport + + + + + The directed movement of choline into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Choline (2-hydroxyethyltrimethylammonium) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine. + GOC:ai + + + + + + + + + + + + + + + + + + + The directed movement of dopamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline. + biological_process + GO:0015872 + dopamine transport + + + + + The directed movement of dopamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline. + GOC:ai + + + + + + + + + + + + + + + + + + + + The directed movement of norepinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine. + levarterenol transport + noradrenaline transport + biological_process + GO:0015874 + norepinephrine transport + + + + + The directed movement of norepinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine. + GOC:ai + ISBN:0198506732 + + + + + + + + + The chemical reactions and pathways by which a cell derives energy from organic compounds; results in the oxidation of the compounds from which energy is released. + chemoorganotrophy + biological_process + GO:0015980 + energy derivation by oxidation of organic compounds + + + + + The chemical reactions and pathways by which a cell derives energy from organic compounds; results in the oxidation of the compounds from which energy is released. + GOC:mah + + + + + + + + + + A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. + 2014-03-06T11:37:54Z + GO:0098589 + GO:0098805 + Wikipedia:Biological_membrane + membrane region + region of membrane + whole membrane + cellular_component + GO:0016020 + + + + + + + + membrane + + + + + A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. + GOC:dos + GOC:mah + ISBN:0815316194 + + + + + + + + + The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. + Wikipedia:Transmembrane_protein + integral to membrane + cellular_component + transmembrane + GO:0016021 + + integral component of membrane + + + + + The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. + GOC:dos + GOC:go_curators + + + + + transmembrane + GOC:mah + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. + GO:0006724 + GO:0044240 + Wikipedia:Lipid_catabolism + lipid breakdown + lipid catabolism + lipid degradation + lipolysis + multicellular organism lipid catabolic process + multicellular organismal lipid catabolic process + biological_process + GO:0016042 + lipid catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component. + GO:0044235 + GO:0071842 + cell organisation + cellular component organisation at cellular level + cellular component organisation in other organism + cellular component organization at cellular level + cellular component organization in other organism + biological_process + cell organization and biogenesis + GO:0016043 + + + + + cellular component organization + + + + + A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component. + GOC:ai + GOC:jl + GOC:mah + + + + + cellular component organisation at cellular level + GOC:mah + + + + + cellular component organisation in other organism + GOC:mah + + + + + cell organization and biogenesis + GOC:mah + + + + + + + + + + + The series of events in which a temperature stimulus (hot or cold) is received and converted into a molecular signal. + detection of temperature + detection of thermal stimulus + biological_process + perception of temperature + GO:0016048 + detection of temperature stimulus + + + + + The series of events in which a temperature stimulus (hot or cold) is received and converted into a molecular signal. + GOC:hb + + + + + + + + + + + + + + + + + + + + + The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present. + GO:0048591 + cellular growth + growth of cell + biological_process + cell expansion + metabolic process resulting in cell growth + metabolism resulting in cell growth + non-developmental cell growth + non-developmental growth of a unicellular organism + GO:0016049 + + + + + cell growth + + + + + The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present. + GOC:ai + + + + + non-developmental cell growth + GOC:mah + + + + + non-developmental growth of a unicellular organism + GOC:mah + + + + + + + + + + + + + + + + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle. + vesicle organisation + biological_process + vesicle organization and biogenesis + GO:0016050 + + + vesicle organization + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle. + GOC:mah + + + + + vesicle organization and biogenesis + GOC:mah + + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. + GO:0006093 + anabolic carbohydrate metabolic process + anabolic carbohydrate metabolism + carbohydrate anabolism + carbohydrate biosynthesis + carbohydrate formation + carbohydrate synthesis + biological_process + GO:0016051 + carbohydrate biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. + jl + 2012-10-23T16:34:39Z + GO:0006095 + GO:0044276 + GO:0044724 + carbohydrate breakdown + carbohydrate catabolism + carbohydrate degradation + catabolic carbohydrate metabolic process + catabolic carbohydrate metabolism + multicellular organismal carbohydrate catabolic process + biological_process + single-organism carbohydrate catabolic process + GO:0016052 + carbohydrate catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of organic acids, any acidic compound containing carbon in covalent linkage. + organic acid anabolism + organic acid biosynthesis + organic acid formation + organic acid synthesis + biological_process + GO:0016053 + organic acid biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of organic acids, any acidic compound containing carbon in covalent linkage. + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage. + organic acid breakdown + organic acid catabolism + organic acid degradation + biological_process + GO:0016054 + organic acid catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage. + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane. + GO:0006899 + vesicle transport + vesicular transport + nonselective vesicle transport + biological_process + protein sorting along secretory pathway + vesicle trafficking + GO:0016192 + + + + + + + vesicle-mediated transport + + + + + A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane. + GOC:ai + GOC:mah + ISBN:08789310662000 + + + + + vesicular transport + GOC:mah + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of striated muscle development. + biological_process + GO:0016202 + regulation of striated muscle tissue development + + + + + Any process that modulates the frequency, rate or extent of striated muscle development. + GOC:go_curators + + + + + + + + + Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. + Reactome:R-HSA-6788855 + Reactome:R-HSA-6788867 + phosphokinase activity + molecular_function + GO:0016301 + + + + + + Note that this term encompasses all activities that transfer a single phosphate group; although ATP is by far the most common phosphate donor, reactions using other phosphate donors are included in this term. + kinase activity + + + + + Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. + ISBN:0198506732 + + + + + Reactome:R-HSA-6788855 + FN3KRP phosphorylates PsiAm, RibAm + + + + + Reactome:R-HSA-6788867 + FN3K phosphorylates ketosamines + + + + + + + + + The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide. + Wikipedia:Phosphorylation + biological_process + GO:0016310 + + + phosphorylation + + + + + The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide. + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the mushroom body over time, from its formation to the mature structure. The mushroom body is composed of the prominent neuropil structures of the insect central brain, thought to be crucial for olfactory associated learning. These consist mainly of a bulbous calyx and tightly packaged arrays of thin parallel fibers of the Kenyon cells. + biological_process + GO:0016319 + mushroom body development + + + + + The process whose specific outcome is the progression of the mushroom body over time, from its formation to the mature structure. The mushroom body is composed of the prominent neuropil structures of the insect central brain, thought to be crucial for olfactory associated learning. These consist mainly of a bulbous calyx and tightly packaged arrays of thin parallel fibers of the Kenyon cells. + PMID:8790424 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Formation and maintenance of a polarized microtubule array originating from a microtubule-organizing center (MTOC) in the oocyte. An example of this is found in Drosophila melanogaster. + GO:0048130 + oocyte microtubule cytoskeleton organisation + biological_process + GO:0016325 + oocyte microtubule cytoskeleton organization + + + + + Formation and maintenance of a polarized microtubule array originating from a microtubule-organizing center (MTOC) in the oocyte. An example of this is found in Drosophila melanogaster. + GOC:mtg_sensu + PMID:11231123 + + + + + + + + + + The process in which the anatomical structures of embryonic epithelia are generated and organized. + biological_process + GO:0016331 + morphogenesis of embryonic epithelium + + + + + The process in which the anatomical structures of embryonic epithelia are generated and organized. + GOC:jl + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the dendrite over time, from its formation to the mature structure. + biological_process + GO:0016358 + dendrite development + + + + + The process whose specific outcome is the progression of the dendrite over time, from its formation to the mature structure. + GOC:aruk + GOC:bc + GOC:jl + ISBN:0198506732 + PMID:22683681 + + + + + + + + + The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms. + Wikipedia:Cell_migration + biological_process + GO:0016477 + cell migration + + + + + The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms. + GOC:cjm + GOC:dph + GOC:ems + GOC:pf + Wikipedia:Cell_migration + + + + + + + + + Combining with a protein hormone to initiate a change in cell activity. + molecular_function + GO:0016500 + protein-hormone receptor activity + + + + + Combining with a protein hormone to initiate a change in cell activity. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + Combining with a pheromone to initiate a change in cell activity. A pheromone is a substance used in olfactory communication between organisms of the same species eliciting a change in sexual or social behavior. + molecular_function + GO:0016503 + pheromone receptor activity + + + + + Combining with a pheromone to initiate a change in cell activity. A pheromone is a substance used in olfactory communication between organisms of the same species eliciting a change in sexual or social behavior. + GOC:hjd + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis. + down regulation of angiogenesis + down-regulation of angiogenesis + downregulation of angiogenesis + inhibition of angiogenesis + biological_process + GO:0016525 + negative regulation of angiogenesis + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The cytoplasm of a muscle cell; includes the sarcoplasmic reticulum. + + Wikipedia:Sarcoplasm + cellular_component + GO:0016528 + sarcoplasm + + + + + The cytoplasm of a muscle cell; includes the sarcoplasmic reticulum. + ISBN:0198547684 + + + + + + + + + + + + + + + + + + + Binding to glutamate, the anion of 2-aminopentanedioic acid. + glutamic acid binding + molecular_function + GO:0016595 + glutamate binding + + + + + Binding to glutamate, the anion of 2-aminopentanedioic acid. + GOC:ai + + + + + + + + + + + + + + + + + + + Binding to an amino acid, organic acids containing one or more amino substituents. + molecular_function + GO:0016597 + + + amino acid binding + + + + + Binding to an amino acid, organic acids containing one or more amino substituents. + GOC:ai + + + + + + + + + Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. + EC:2.-.-.- + Reactome:R-HSA-1483089 + Reactome:R-HSA-1483186 + Reactome:R-HSA-5668414 + Reactome:R-HSA-8868783 + molecular_function + GO:0016740 + + + + + + + + + + + transferase activity + + + + + Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. + ISBN:0198506732 + + + + + Reactome:R-HSA-1483089 + PE is converted to PS by PTDSS2 + + + + + Reactome:R-HSA-1483186 + PC is converted to PS by PTDSS1 + + + + + Reactome:R-HSA-5668414 + TRAF2 ubiquitinates cIAP1,2 in cIAP1,2:TRAF1:TRAF2:TRAF3:NIK + + + + + Reactome:R-HSA-8868783 + TSR3 transfers aminocarboxypropyl group from S-adenosylmethionine to N(1)-methylpseudouridine-1248 of 18SE rRNA yielding N(1)-methyl-N(3)-aminocarboxypropylpseudouridine-1248 + + + + + + + + + Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor). + EC:2.7.-.- + molecular_function + GO:0016772 + + Note that this term encompasses all kinase activities, as well as activities that transfer other phosphorus-containing groups such as diphosphate or nucleotides. + transferase activity, transferring phosphorus-containing groups + + + + + Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor). + GOC:jl + ISBN:0198506732 + + + + + + + + + Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to an alcohol group (acceptor). + EC:2.7.1.- + Reactome:R-HSA-2161193 + molecular_function + GO:0016773 + + phosphotransferase activity, alcohol group as acceptor + + + + + Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to an alcohol group (acceptor). + GOC:jl + + + + + Reactome:R-HSA-2161193 + abacavir + AMP => abacavir monophosphate + adenosine + + + + + + + + + + + + + + + + + + + + Combining with gamma-aminobutyric acid (GABA), and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. (GABA, 4-aminobutyrate) is an amino acid which acts as a neurotransmitter in some organisms. + 4-aminobutanoate receptor activity + 4-aminobutyrate receptor activity + GABA binding + gamma-aminobutyrate binding + gamma-aminobutyric acid binding + gamma-aminobutyric acid receptor activity + molecular_function + GO:0016917 + See also the molecular function term 'neurotransmitter receptor activity ; GO:0030594'. + GABA receptor activity + + + + + Combining with gamma-aminobutyric acid (GABA), and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. (GABA, 4-aminobutyrate) is an amino acid which acts as a neurotransmitter in some organisms. + GOC:jl + GOC:signaling + PMID:10637650 + + + + + + + + + + + + + + + + + + + + Binding to a peptide with hormonal activity in animals. + polypeptide hormone binding + molecular_function + GO:0017046 + peptide hormone binding + + + + + Binding to a peptide with hormonal activity in animals. + GOC:jl + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + The self-renewing division of a stem cell. A stem cell is an undifferentiated cell, in the embryo or adult, that can undergo unlimited division and give rise to one or several different cell types. + stem cell renewal + biological_process + GO:0017145 + stem cell division + + + + + The self-renewing division of a stem cell. A stem cell is an undifferentiated cell, in the embryo or adult, that can undergo unlimited division and give rise to one or several different cell types. + GOC:jid + ISBN:0582227089 + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of exocytosis. + biological_process + GO:0017157 + regulation of exocytosis + + + + + Any process that modulates the frequency, rate or extent of exocytosis. + GOC:go_curators + + + + + + + + + + The phosphorylation of peptidyl-tyrosine to form peptidyl-O4'-phospho-L-tyrosine. + RESID:AA0039 + biological_process + GO:0018108 + peptidyl-tyrosine phosphorylation + + + + + The phosphorylation of peptidyl-tyrosine to form peptidyl-O4'-phospho-L-tyrosine. + RESID:AA0039 + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings). + heterocycle anabolism + heterocycle biosynthesis + heterocycle formation + heterocycle synthesis + biological_process + GO:0018130 + heterocycle biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings). + ISBN:0198547684 + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues. + RESID:AA0247 + keratan sulfate anabolism + keratan sulfate biosynthesis + keratan sulfate formation + keratan sulfate synthesis + keratan sulphate biosynthesis + keratan sulphate biosynthetic process + biological_process + GO:0018146 + keratan sulfate biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues. + ISBN:0198547684 + RESID:AA0247 + + + + + + + + + + + + + + + The alteration of an amino acid residue in a peptide. + biological_process + GO:0018193 + + peptidyl-amino acid modification + + + + + The alteration of an amino acid residue in a peptide. + GOC:mah + + + + + + + + + The modification of peptidyl-tyrosine. + biological_process + GO:0018212 + peptidyl-tyrosine modification + + + + + The modification of peptidyl-tyrosine. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring. + UM-BBD_pathwayID:phe + carbolic acid metabolic process + carbolic acid metabolism + hydroxybenzene metabolic process + hydroxybenzene metabolism + phenol-containing compound metabolism + biological_process + GO:0018958 + Note that phenol metabolism is not included as a child of 'xenobiotic metabolism' because although it is synthesized industrially, phenol is also found naturally in animal wastes and other organic materials. It is often formed by the activity of microorganisms, which can chemically modify a variety of xenobiotic and naturally occurring phenolic compounds. + phenol-containing compound metabolic process + + + + + The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring. + ISBN:0198506732 + + + + + + + + + + + + + + + The first process of molting, characterized by the detachment of the old cuticle from the underlying epidermal cells. + Wikipedia:Apolysis + biological_process + GO:0018989 + apolysis + + + + + The first process of molting, characterized by the detachment of the old cuticle from the underlying epidermal cells. + GOC:jl + + + + + + + + + + + + + + + + + + + + + + The specific behavior of an organism that is associated with reproduction. + jl + 2012-09-19T16:01:37Z + GO:0033057 + GO:0044704 + GO:0044705 + reproductive behavior in a multicellular organism + reproductive behaviour + multi-organism reproductive behavior + multicellular organism reproductive behavior + biological_process + single-organism reproductive behavior + GO:0019098 + reproductive behavior + + + + + The specific behavior of an organism that is associated with reproduction. + GOC:jl + GOC:pr + + + + + + + + + + Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: a protein + ATP = a phosphoprotein + ADP. + Reactome:R-HSA-8983059 + Reactome:R-HSA-8983063 + molecular_function + GO:0019199 + transmembrane receptor protein kinase activity + + + + + Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: a protein + ATP = a phosphoprotein + ADP. + GOC:mah + + + + + Reactome:R-HSA-8983059 + STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex + + + + + Reactome:R-HSA-8983063 + JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated + + + + + + + + + + + + + + + + + + + Modulates the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule. + molecular_function + GO:0019207 + kinase regulator activity + + + + + Modulates the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule. + GOC:ai + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Binds to and increases the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule. + molecular_function + GO:0019209 + kinase activator activity + + + + + Binds to and increases the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule. + GOC:ai + + + + + + + + + + + + + + + + + + + Binds to and stops, prevents or reduces the activity of a kinase. + molecular_function + GO:0019210 + kinase inhibitor activity + + + + + Binds to and stops, prevents or reduces the activity of a kinase. + GOC:mah + + + + + + + + + + + + + + + + + + + + Binding to an intermediate filament, a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of higher eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. + molecular_function + GO:0019215 + intermediate filament binding + + + + + Binding to an intermediate filament, a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of higher eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids. + regulation of lipid metabolism + biological_process + GO:0019216 + regulation of lipid metabolic process + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving steroids. + regulation of steroid metabolism + biological_process + GO:0019218 + regulation of steroid metabolic process + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving steroids. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates. + regulation of phosphate metabolism + biological_process + GO:0019220 + regulation of phosphate metabolic process + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. + GO:0044246 + regulation of metabolism + regulation of multicellular organismal metabolic process + regulation of organismal metabolic process + biological_process + GO:0019222 + + regulation of metabolic process + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism. + GOC:go_curators + + + + + regulation of organismal metabolic process + GOC:tb + + + + + + + + + + + + + + + The series of events by which an organism senses the position, location, orientation, and movement of the body and its parts. Proprioception is mediated by proprioceptors, sensory nerve terminals found in muscles, tendons, and joint capsules, which give information concerning movements and position of the body. The receptors in the labyrinth are sometimes also considered proprioceptors. + Wikipedia:Proprioception + biological_process + GO:0019230 + proprioception + + + + + The series of events by which an organism senses the position, location, orientation, and movement of the body and its parts. Proprioception is mediated by proprioceptors, sensory nerve terminals found in muscles, tendons, and joint capsules, which give information concerning movements and position of the body. The receptors in the labyrinth are sometimes also considered proprioceptors. + ISBN:072168677X + + + + + + + + + The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process. + Wikipedia:Nociception + nociception + perception of physiological pain + biological_process + GO:0019233 + sensory perception of pain + + + + + The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process. + GOC:curators + + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus. + pheromone response + biological_process + GO:0019236 + response to pheromone + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus. + GOC:jl + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways involving a hexose, any monosaccharide with a chain of six carbon atoms in the molecule. + hexose metabolism + biological_process + GO:0019318 + hexose metabolic process + + + + + The chemical reactions and pathways involving a hexose, any monosaccharide with a chain of six carbon atoms in the molecule. + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of hexose, any monosaccharide with a chain of six carbon atoms in the molecule. + hexose anabolism + hexose biosynthesis + hexose formation + hexose synthesis + biological_process + GO:0019319 + hexose biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of hexose, any monosaccharide with a chain of six carbon atoms in the molecule. + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of hexose, any monosaccharide with a chain of six carbon atoms in the molecule. + hexose breakdown + hexose catabolism + hexose degradation + biological_process + GO:0019320 + hexose catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of hexose, any monosaccharide with a chain of six carbon atoms in the molecule. + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring. + MetaCyc:PHENOLDEG-PWY + phenol-containing compound breakdown + phenol-containing compound catabolism + phenol-containing compound degradation + biological_process + GO:0019336 + phenol-containing compound catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring. + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of aromatic compounds, any substance containing an aromatic carbon ring. + aromatic compound anabolism + aromatic compound biosynthesis + aromatic compound formation + aromatic compound synthesis + aromatic hydrocarbon biosynthesis + aromatic hydrocarbon biosynthetic process + biological_process + GO:0019438 + aromatic compound biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of aromatic compounds, any substance containing an aromatic carbon ring. + GOC:ai + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of aromatic compounds, any substance containing an aromatic carbon ring. + aromatic compound breakdown + aromatic compound catabolism + aromatic compound degradation + aromatic hydrocarbon catabolic process + aromatic hydrocarbon catabolism + biological_process + GO:0019439 + aromatic compound catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of aromatic compounds, any substance containing an aromatic carbon ring. + GOC:ai + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways involving a protein. Includes protein modification. + https://github.com/geneontology/go-ontology/issues/23112 + GO:0006411 + GO:0044267 + GO:0044268 + Wikipedia:Protein_metabolism + cellular protein metabolic process + cellular protein metabolism + protein metabolic process and modification + protein metabolism + protein metabolism and modification + multicellular organismal protein metabolic process + biological_process + GO:0019538 + + + + + + protein metabolic process + + + + + The chemical reactions and pathways involving a protein. Includes protein modification. + GOC:ma + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent. + biological_process + catechol breakdown + catechol catabolic process + catechol catabolism + catechol degradation + GO:0019614 + catechol-containing compound catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways involving choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine. + choline metabolism + biological_process + GO:0019695 + choline metabolic process + + + + + The chemical reactions and pathways involving choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine. + GOC:jl + ISBN:0192801023 + + + + + + + + + + + + + + + + + + + + + Any process involved with the carrying out of an immune response by a B cell, through, for instance, the production of antibodies or cytokines, or antigen presentation to T cells. + B lymphocyte mediated immune effector process + B lymphocyte mediated immunity + B-cell mediated immune effector process + B-cell mediated immunity + B-lymphocyte mediated immune effector process + B-lymphocyte mediated immunity + biological_process + GO:0019724 + B cell mediated immunity + + + + + Any process involved with the carrying out of an immune response by a B cell, through, for instance, the production of antibodies or cytokines, or antigen presentation to T cells. + GOC:add + GO_REF:0000022 + ISBN:0781735149 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Any process involved in the maintenance of an internal steady state at the level of the cell. + biological_process + GO:0019725 + + + cellular homeostasis + + + + + Any process involved in the maintenance of an internal steady state at the level of the cell. + GOC:isa_complete + GOC:jl + ISBN:0395825172 + + + + + + + + + The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients. + Wikipedia:Secondary_metabolism + secondary metabolism + secondary metabolite metabolic process + secondary metabolite metabolism + biological_process + GO:0019748 + + + + + secondary metabolic process + + + + + The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-). + carboxylic acid metabolism + biological_process + GO:0019752 + carboxylic acid metabolic process + + + + + The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-). + ISBN:0198506732 + + + + + + + + + The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites. + cellular_component + GO:0019867 + + outer membrane + + + + + The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + + + + + Modulates the activity of a protein kinase, an enzyme which phosphorylates a protein. + molecular_function + GO:0019887 + protein kinase regulator activity + + + + + Modulates the activity of a protein kinase, an enzyme which phosphorylates a protein. + GOC:ai + + + + + + + + + Binding to an enzyme, a protein with catalytic activity. + molecular_function + GO:0019899 + + + enzyme binding + + + + + Binding to an enzyme, a protein with catalytic activity. + GOC:jl + + + + + + + + + Binding to a kinase, any enzyme that catalyzes the transfer of a phosphate group. + molecular_function + GO:0019900 + kinase binding + + + + + Binding to a kinase, any enzyme that catalyzes the transfer of a phosphate group. + GOC:jl + + + + + + + + + Binding to a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate. + molecular_function + GO:0019901 + protein kinase binding + + + + + Binding to a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate. + GOC:jl + + + + + + + + + A type of reproduction that combines the genetic material of two gametes (such as a sperm or egg cell or fungal spores). The gametes have an haploid genome (with a single set of chromosomes, the product of a meiotic division) and combines with one another to produce a zygote (diploid). + https://github.com/geneontology/go-ontology/issues/22929 + Wikipedia:Sexual_reproduction + biological_process + GO:0019953 + Note that gametes may come from two organisms or from a single organism in the case of self-fertilizing hermaphrodites, e.g. C. elegans, or self-fertilization in plants. Note also that sexual reproduction may be seen as the regular alternation, in the life cycle of haplontic, diplontic and diplohaplontic organisms, of meiosis and fertilization which provides for the production offspring. In diplontic organisms there is a life cycle in which the products of meiosis behave directly as gametes, fusing to form a zygote from which the diploid, or sexually reproductive polyploid, adult organism will develop. In diplohaplontic organisms a haploid phase (gametophyte) exists in the life cycle between meiosis and fertilization (e.g. higher plants, many algae and Fungi); the products of meiosis are spores that develop as haploid individuals from which haploid gametes develop to form a diploid zygote; diplohaplontic organisms show an alternation of haploid and diploid generations. In haplontic organisms meiosis occurs in the zygote, giving rise to four haploid cells (e.g. many algae and protozoa), only the zygote is diploid and this may form a resistant spore, tiding organisms over hard times. + sexual reproduction + + + + + A type of reproduction that combines the genetic material of two gametes (such as a sperm or egg cell or fungal spores). The gametes have an haploid genome (with a single set of chromosomes, the product of a meiotic division) and combines with one another to produce a zygote (diploid). + Wikipedia:Sexual_reproduction + + + + + + + + + + + + + + + + + + + + + + + + + + + The formation of the prechordal plate. The prechordal plate is a thickening of the endoderm at the cranial end of the primitive streak formed by the involution of Spemann's organizer cells. The prechordal plate and the notochord induce the formation of the neural plate from the overlying ectodermal cells. + biological_process + GO:0021501 + prechordal plate formation + + + + + The formation of the prechordal plate. The prechordal plate is a thickening of the endoderm at the cranial end of the primitive streak formed by the involution of Spemann's organizer cells. The prechordal plate and the notochord induce the formation of the neural plate from the overlying ectodermal cells. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + The morphogenesis of the neural fold elevations that results in the movement of the tips of the elevations towards each other in order to fuse. + biological_process + GO:0021503 + neural fold bending + + + + + The morphogenesis of the neural fold elevations that results in the movement of the tips of the elevations towards each other in order to fuse. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + PMID:15806586 + + + + + + + + + + + + + + + + + + + + + + + + + + + The formation of the median and lateral hinge points in the neural folds. These are created by apical constriction and basal expansion of the underlying neural cells. The median hinge point extends for the entire length of the neural tube, and the lateral hinge points do not form in the spinal cord region of the neural tube. + neural fold furrowing + biological_process + GO:0021504 + neural fold hinge point formation + + + + + The formation of the median and lateral hinge points in the neural folds. These are created by apical constriction and basal expansion of the underlying neural cells. The median hinge point extends for the entire length of the neural tube, and the lateral hinge points do not form in the spinal cord region of the neural tube. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + PMID:13679871 + PMID:15806586 + + + + + neural fold furrowing + GOC:cls + + + + + + + + + + + + + + + The joining together of the neural folds of the rostral opening of the neural tube. The anterior neuropore appears before the process of neural tube closure is complete. + biological_process + GO:0021506 + anterior neuropore closure + + + + + The joining together of the neural folds of the rostral opening of the neural tube. The anterior neuropore appears before the process of neural tube closure is complete. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The formation of a ventral region of glial cells in the neural tube that provides inductive signals for the specification of neuronal cell types. The floor plate is evident at the ventral midline by the neural fold stage. + biological_process + GO:0021508 + floor plate formation + + + + + The formation of a ventral region of glial cells in the neural tube that provides inductive signals for the specification of neuronal cell types. The floor plate is evident at the ventral midline by the neural fold stage. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + PMID:11262869 + + + + + + + + + + + + + + + + + + + + + + + + + + + The formation of a single row of glia at the dorsal midline of the developing neural tube. This region provides inductive signals for the specification of neuronal cell types and of the specification of neural crest cells. The cells comprising the roof plate are the precursors to radial glial cells. + biological_process + GO:0021509 + roof plate formation + + + + + The formation of a single row of glia at the dorsal midline of the developing neural tube. This region provides inductive signals for the specification of neuronal cell types and of the specification of neural crest cells. The cells comprising the roof plate are the precursors to radial glial cells. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + PMID:15936325 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues. + biological_process + GO:0021510 + spinal cord development + + + + + The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of ventral spinal cord interneurons. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses. Differentiation includes the processes involved in commitment of a cell to a specific fate. + biological_process + GO:0021514 + ventral spinal cord interneuron differentiation + + + + + The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of ventral spinal cord interneurons. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses. Differentiation includes the processes involved in commitment of a cell to a specific fate. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + PMID:11262869 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate. + biological_process + GO:0021515 + cell differentiation in spinal cord + + + + + The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + PMID:11262869 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the dorsal region of the spinal cord over time, from its formation to the mature structure. The dorsal region of the mature spinal cord contains neurons that process and relay sensory input. + biological_process + GO:0021516 + dorsal spinal cord development + + + + + The process whose specific outcome is the progression of the dorsal region of the spinal cord over time, from its formation to the mature structure. The dorsal region of the mature spinal cord contains neurons that process and relay sensory input. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + PMID:11179871 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the ventral region of the spinal cord over time, from its formation to the mature structure. The neurons of the ventral region of the mature spinal cord participate in motor output. + biological_process + GO:0021517 + ventral spinal cord development + + + + + The process whose specific outcome is the progression of the ventral region of the spinal cord over time, from its formation to the mature structure. The neurons of the ventral region of the mature spinal cord participate in motor output. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + The regionalization process that regulates the coordinated growth that establishes the non-random spatial arrangement of the neural tube. + biological_process + GO:0021532 + neural tube patterning + + + + + The regionalization process that regulates the coordinated growth that establishes the non-random spatial arrangement of the neural tube. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mature cells of the hindbrain. Differentiation includes the processes involved in commitment of a cell to a specific fate. + biological_process + GO:0021533 + cell differentiation in hindbrain + + + + + The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mature cells of the hindbrain. Differentiation includes the processes involved in commitment of a cell to a specific fate. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain. + biological_process + GO:0021534 + cell proliferation in hindbrain + + + + + The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The orderly movement of a cell that will reside in the hindbrain. + biological_process + GO:0021535 + cell migration in hindbrain + + + + + The orderly movement of a cell that will reside in the hindbrain. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the diencephalon over time, from its formation to the mature structure. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex. + biological_process + GO:0021536 + diencephalon development + + + + + The process whose specific outcome is the progression of the diencephalon over time, from its formation to the mature structure. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the telencephalon over time, from its formation to the mature structure. The telencephalon is the paired anteriolateral division of the prosencephalon plus the lamina terminalis from which the olfactory lobes, cerebral cortex, and subcortical nuclei are derived. + cerebrum development + biological_process + GO:0021537 + telencephalon development + + + + + The process whose specific outcome is the progression of the telencephalon over time, from its formation to the mature structure. The telencephalon is the paired anteriolateral division of the prosencephalon plus the lamina terminalis from which the olfactory lobes, cerebral cortex, and subcortical nuclei are derived. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + PMID:12626695 + + + + + cerebrum development + GOC:sl + PMID:22331407 + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the epithalamus over time from its initial formation until its mature state. The epithalamus is the small dorsomedial area of the thalamus including the habenular nuclei and associated fiber bundles, the pineal body, and the epithelial roof of the third ventricle. + biological_process + GO:0021538 + epithalamus development + + + + + The progression of the epithalamus over time from its initial formation until its mature state. The epithalamus is the small dorsomedial area of the thalamus including the habenular nuclei and associated fiber bundles, the pineal body, and the epithelial roof of the third ventricle. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the subthalamus over time, from its formation to the mature structure. The subthalamus is the anterior part of the diencephalon that lies between the thalamus, hypothalamus, and tegmentum of the mesencephalon, including subthalamic nucleus, zona incerta, the fields of Forel, and the nucleus of ansa lenticularis. + biological_process + ventral thalamus development + GO:0021539 + subthalamus development + + + + + The process whose specific outcome is the progression of the subthalamus over time, from its formation to the mature structure. The subthalamus is the anterior part of the diencephalon that lies between the thalamus, hypothalamus, and tegmentum of the mesencephalon, including subthalamic nucleus, zona incerta, the fields of Forel, and the nucleus of ansa lenticularis. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + ventral thalamus development + GOC:cls + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the corpus callosum are generated and organized. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provides communications between the right and left cerebral hemispheres. + biological_process + GO:0021540 + corpus callosum morphogenesis + + + + + The process in which the anatomical structures of the corpus callosum are generated and organized. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provides communications between the right and left cerebral hemispheres. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the ammon gyrus over time, from its formation to the mature structure. The ammon gyrus, often subdivided into the CA1 and CA3 regions, is one of the two interlocking gyri of the hippocampus that is rich in large pyramidal neurons. + biological_process + Ammon's horn development + cornu ammonis development + GO:0021541 + ammon gyrus development + + + + + The process whose specific outcome is the progression of the ammon gyrus over time, from its formation to the mature structure. The ammon gyrus, often subdivided into the CA1 and CA3 regions, is one of the two interlocking gyri of the hippocampus that is rich in large pyramidal neurons. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + Ammon's horn development + GOC:cls + + + + + cornu ammonis development + GOC:cls + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the dentate gyrus over time, from its formation to the mature structure. The dentate gyrus is one of two interlocking gyri of the hippocampus. It contains granule cells, which project to the pyramidal cells and interneurons of the CA3 region of the ammon gyrus. + biological_process + GO:0021542 + dentate gyrus development + + + + + The process whose specific outcome is the progression of the dentate gyrus over time, from its formation to the mature structure. The dentate gyrus is one of two interlocking gyri of the hippocampus. It contains granule cells, which project to the pyramidal cells and interneurons of the CA3 region of the ammon gyrus. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the pallium over time, from its formation to the mature structure. The pallium is the roof region of the telencephalon. + biological_process + GO:0021543 + pallium development + + + + + The process whose specific outcome is the progression of the pallium over time, from its formation to the mature structure. The pallium is the roof region of the telencephalon. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + PMID:12626695 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the subpallium over time, from its formation to the mature structure. The subpallium is the base region of the telencephalon. + biological_process + GO:0021544 + subpallium development + + + + + The process whose specific outcome is the progression of the subpallium over time, from its formation to the mature structure. The subpallium is the base region of the telencephalon. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + PMID:12626695 + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the cranial nerves over time, from its formation to the mature structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions. + biological_process + GO:0021545 + cranial nerve development + + + + + The process whose specific outcome is the progression of the cranial nerves over time, from its formation to the mature structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the rhombomere over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. + biological_process + GO:0021546 + rhombomere development + + + + + The process whose specific outcome is the progression of the rhombomere over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The regionalization process that gives rise to the midbrain-hindbrain boundary. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate. + MHB biosynthesis + MHB formation + midbrain-hindbrain boundary biosynthesis + midbrain-hindbrain boundary formation + biological_process + isthmus biosynthesis + isthmus formation + GO:0021547 + midbrain-hindbrain boundary initiation + + + + + The regionalization process that gives rise to the midbrain-hindbrain boundary. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate. + GOC:cls + GOC:dgh + GOC:dph + GOC:isa_complete + GOC:jid + GO_REF:0000021 + PMID:15541513 + + + + + MHB biosynthesis + GOC:cls + + + + + MHB formation + GOC:cls + + + + + midbrain-hindbrain boundary biosynthesis + GOC:cls + + + + + midbrain-hindbrain boundary formation + GOC:cls + + + + + isthmus biosynthesis + GOC:cls + + + + + isthmus formation + GOC:cls + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the pons over time, from its formation to the mature structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum. + biological_process + GO:0021548 + pons development + + + + + The process whose specific outcome is the progression of the pons over time, from its formation to the mature structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the cerebellum over time, from its formation to the mature structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. In mice, the cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills. + biological_process + GO:0021549 + cerebellum development + + + + + The process whose specific outcome is the progression of the cerebellum over time, from its formation to the mature structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. In mice, the cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the medulla oblongata over time, from its formation to the mature structure. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate. + biological_process + medulla development + myelencephalon development + GO:0021550 + medulla oblongata development + + + + + The process whose specific outcome is the progression of the medulla oblongata over time, from its formation to the mature structure. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + medulla development + GOC:cls + + + + + myelencephalon development + GOC:cls + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of the central nervous system is generated and organized. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. + biological_process + GO:0021551 + central nervous system morphogenesis + + + + + The process in which the anatomical structure of the central nervous system is generated and organized. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0582227089 + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the olfactory nerve over time, from its formation to the mature structure. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem. + cranial nerve 1 development + cranial nerve I development + biological_process + CN 1 development + GO:0021553 + olfactory nerve development + + + + + The process whose specific outcome is the progression of the olfactory nerve over time, from its formation to the mature structure. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + cranial nerve 1 development + GOC:cls + + + + + cranial nerve I development + GOC:cls + + + + + CN 1 development + GOC:cls + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the optic nerve over time, from its formation to the mature structure. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain. + cranial nerve 2 development + cranial nerve II development + biological_process + CN II development + GO:0021554 + optic nerve development + + + + + The process whose specific outcome is the progression of the optic nerve over time, from its formation to the mature structure. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + cranial nerve 2 development + GOC:cls + + + + + cranial nerve II development + GOC:cls + + + + + CN II development + GOC:cls + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of the midbrain-hindbrain boundary is generated and organized. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate. + MHB morphogenesis + isthmus morphogenesis + biological_process + GO:0021555 + midbrain-hindbrain boundary morphogenesis + + + + + The process in which the anatomical structure of the midbrain-hindbrain boundary is generated and organized. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + PMID:15541513 + + + + + MHB morphogenesis + GOC:cls + + + + + isthmus morphogenesis + GOC:cls + + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to the central nervous system. This process pertains to the initial formation of a structure from unspecified parts. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. + biological_process + GO:0021556 + central nervous system formation + + + + + The process that gives rise to the central nervous system. This process pertains to the initial formation of a structure from unspecified parts. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0582227089 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the oculomotor nerve over time, from its formation to the mature structure. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle. + cranial nerve 3 development + cranial nerve III development + biological_process + CN III development + GO:0021557 + oculomotor nerve development + + + + + The process whose specific outcome is the progression of the oculomotor nerve over time, from its formation to the mature structure. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + cranial nerve 3 development + GOC:cls + + + + + cranial nerve III development + GOC:cls + + + + + CN III development + GOC:cls + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the trochlear nerve over time, from its formation to the mature structure. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle. + cranial nerve 4 development + cranial nerve IV development + biological_process + CN IV development + GO:0021558 + trochlear nerve development + + + + + The process whose specific outcome is the progression of the trochlear nerve over time, from its formation to the mature structure. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + cranial nerve 4 development + GOC:cls + + + + + cranial nerve IV development + GOC:cls + + + + + CN IV development + GOC:cls + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the trigeminal nerve over time, from its formation to the mature structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae. + cranial nerve 5 development + cranial nerve V development + biological_process + CN V development + GO:0021559 + trigeminal nerve development + + + + + The process whose specific outcome is the progression of the trigeminal nerve over time, from its formation to the mature structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + cranial nerve 5 development + GOC:cls + + + + + cranial nerve V development + GOC:cls + + + + + CN V development + GOC:cls + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the abducens nerve over time, from its formation to the mature structure. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye. + cranial nerve 6 development + cranial nerve VI development + biological_process + CN VI development + GO:0021560 + abducens nerve development + + + + + The process whose specific outcome is the progression of the abducens nerve over time, from its formation to the mature structure. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + cranial nerve 6 development + GOC:cls + + + + + cranial nerve VI development + GOC:cls + + + + + CN VI development + GOC:cls + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the facial nerve over time, from its formation to the mature structure. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives off nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities. + cranial nerve 7 development + cranial nerve VII development + biological_process + CN VII development + GO:0021561 + facial nerve development + + + + + The process whose specific outcome is the progression of the facial nerve over time, from its formation to the mature structure. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives off nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + cranial nerve 7 development + GOC:cls + + + + + cranial nerve VII development + GOC:cls + + + + + CN VII development + GOC:cls + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the vestibulocochlear nerve over time, from its formation to the mature structure. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea. + CN VIII development + acoustic nerve development + cranial nerve 8 development + cranial nerve VIII development + biological_process + GO:0021562 + vestibulocochlear nerve development + + + + + The process whose specific outcome is the progression of the vestibulocochlear nerve over time, from its formation to the mature structure. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + CN VIII development + GOC:cls + + + + + acoustic nerve development + PMID:11533729 + + + + + cranial nerve 8 development + GOC:cls + + + + + cranial nerve VIII development + GOC:cls + + + + + + + + + + + + + + + + + + + + Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion. + cranial nerve 9 development + cranial nerve IX development + biological_process + CN IX development + GO:0021563 + glossopharyngeal nerve development + + + + + Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + cranial nerve 9 development + GOC:cls + + + + + cranial nerve IX development + GOC:cls + + + + + CN IX development + GOC:cls + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the vagus nerve over time, from its formation to the mature structure. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis. + cranial nerve X development + biological_process + CN X development + cranial nerve 10 development + GO:0021564 + vagus nerve development + + + + + The process whose specific outcome is the progression of the vagus nerve over time, from its formation to the mature structure. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + cranial nerve X development + GOC:cls + + + + + CN X development + GOC:cls + + + + + cranial nerve 10 development + GOC:cls + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the accessory nerve over time, from its formation to the mature structure. In mice, the spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve. + cranial nerve XI development + spinal accessory nerve development + biological_process + CN XI development + cranial nerve 11 development + GO:0021565 + accessory nerve development + + + + + The process whose specific outcome is the progression of the accessory nerve over time, from its formation to the mature structure. In mice, the spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + cranial nerve XI development + GOC:cls + + + + + spinal accessory nerve development + PMID:11533729 + + + + + CN XI development + GOC:cls + + + + + cranial nerve 11 development + GOC:cls + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the hypoglossal nerve over time, from its formation to the mature structure. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue. + cranial nerve XII development + biological_process + CN XII development + cranial nerve 12 development + GO:0021566 + hypoglossal nerve development + + + + + The process whose specific outcome is the progression of the hypoglossal nerve over time, from its formation to the mature structure. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + cranial nerve XII development + GOC:cls + + + + + CN XII development + GOC:cls + + + + + cranial nerve 12 development + GOC:cls + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of rhombomere 1 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. + biological_process + GO:0021567 + rhombomere 1 development + + + + + The process whose specific outcome is the progression of rhombomere 1 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of rhombomere 2 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. + biological_process + GO:0021568 + rhombomere 2 development + + + + + The process whose specific outcome is the progression of rhombomere 2 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of rhombomere 3 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. + biological_process + GO:0021569 + rhombomere 3 development + + + + + The process whose specific outcome is the progression of rhombomere 3 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of rhombomere 4 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. + biological_process + GO:0021570 + rhombomere 4 development + + + + + The process whose specific outcome is the progression of rhombomere 4 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of rhombomere 5 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. + biological_process + GO:0021571 + rhombomere 5 development + + + + + The process whose specific outcome is the progression of rhombomere 5 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of rhombomere 6 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. + biological_process + GO:0021572 + rhombomere 6 development + + + + + The process whose specific outcome is the progression of rhombomere 6 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of rhombomere 7 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. + biological_process + GO:0021573 + rhombomere 7 development + + + + + The process whose specific outcome is the progression of rhombomere 7 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of rhombomere 8 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. + biological_process + GO:0021574 + rhombomere 8 development + + + + + The process whose specific outcome is the progression of rhombomere 8 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of the hindbrain is generated and organized. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions. + biological_process + rhombencephalon morphogenesis + GO:0021575 + hindbrain morphogenesis + + + + + The process in which the anatomical structure of the hindbrain is generated and organized. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to the hindbrain. This process pertains to the initial formation of a structure from unspecified parts. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions. + biological_process + GO:0021576 + hindbrain formation + + + + + The process that gives rise to the hindbrain. This process pertains to the initial formation of a structure from unspecified parts. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the hindbrain to attain its fully functional state. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions. + biological_process + GO:0021578 + hindbrain maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the hindbrain to attain its fully functional state. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of the medulla oblongata is generated and organized. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate. + biological_process + medulla morphogenesis + myelencephalon morphogenesis + GO:0021579 + medulla oblongata morphogenesis + + + + + The process in which the anatomical structure of the medulla oblongata is generated and organized. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to the medulla oblongata. This process pertains to the initial formation of a structure from unspecified parts. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate. + biological_process + medulla biosynthesis + medulla formation + myelencephalon biosynthesis + myelencephalon formation + GO:0021580 + medulla oblongata formation + + + + + The process that gives rise to the medulla oblongata. This process pertains to the initial formation of a structure from unspecified parts. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the medulla oblongata to attain its fully functional state. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate. + biological_process + medulla maturation + myelencephalon maturation + GO:0021582 + medulla oblongata maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the medulla oblongata to attain its fully functional state. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of the pons is generated and organized. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum. + biological_process + GO:0021583 + pons morphogenesis + + + + + The process in which the anatomical structure of the pons is generated and organized. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to the pons. This process pertains to the initial formation of a structure from unspecified parts. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum. + biological_process + GO:0021584 + pons formation + + + + + The process that gives rise to the pons. This process pertains to the initial formation of a structure from unspecified parts. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the pons to attain its fully functional state. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum. + biological_process + GO:0021586 + pons maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the pons to attain its fully functional state. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of the cerebellum is generated and organized. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills. + biological_process + GO:0021587 + cerebellum morphogenesis + + + + + The process in which the anatomical structure of the cerebellum is generated and organized. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to the cerebellum. This process pertains to the initial formation of a structure from unspecified parts. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills. + biological_process + GO:0021588 + cerebellum formation + + + + + The process that gives rise to the cerebellum. This process pertains to the initial formation of a structure from unspecified parts. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellum to attain its fully functional state. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills. + biological_process + GO:0021590 + cerebellum maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellum to attain its fully functional state. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the brain ventricular system over time, from its formation to the mature structure. The brain ventricular system consists of four communicating cavities within the brain that are continuous with the central canal of the spinal cord. These cavities include two lateral ventricles, the third ventricle and the fourth ventricle. Cerebrospinal fluid fills the ventricles and is produced by the choroid plexus. + biological_process + GO:0021591 + ventricular system development + + + + + The process whose specific outcome is the progression of the brain ventricular system over time, from its formation to the mature structure. The brain ventricular system consists of four communicating cavities within the brain that are continuous with the central canal of the spinal cord. These cavities include two lateral ventricles, the third ventricle and the fourth ventricle. Cerebrospinal fluid fills the ventricles and is produced by the choroid plexus. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the fourth ventricle over time, from its formation to the mature structure. The fourth ventricle is an irregularly shaped cavity in the rhombencephalon, between the medulla oblongata, the pons, and the isthmus in front, and the cerebellum behind. It is continuous with the central canal of the cord below and with the cerebral aqueduct above, and through its lateral and median apertures it communicates with the subarachnoid space. + biological_process + GO:0021592 + fourth ventricle development + + + + + The process whose specific outcome is the progression of the fourth ventricle over time, from its formation to the mature structure. The fourth ventricle is an irregularly shaped cavity in the rhombencephalon, between the medulla oblongata, the pons, and the isthmus in front, and the cerebellum behind. It is continuous with the central canal of the cord below and with the cerebral aqueduct above, and through its lateral and median apertures it communicates with the subarachnoid space. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of the rhombomere is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. + biological_process + GO:0021593 + rhombomere morphogenesis + + + + + The process in which the anatomical structure of the rhombomere is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to the rhombomere. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. + biological_process + GO:0021594 + rhombomere formation + + + + + The process that gives rise to the rhombomere. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of the abducens nerve is generated and organized. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye. + biological_process + CN VI development + GO:0021598 + abducens nerve morphogenesis + + + + + The process in which the anatomical structure of the abducens nerve is generated and organized. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to the abducens nerve. This process pertains to the initial formation of a structure from unspecified parts. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye. + biological_process + CN VI biosynthesis + CN VI formation + GO:0021599 + abducens nerve formation + + + + + The process that gives rise to the abducens nerve. This process pertains to the initial formation of a structure from unspecified parts. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the abducens nerve to attain its fully functional state. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye. + biological_process + CN VI maturation + GO:0021601 + abducens nerve maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the abducens nerve to attain its fully functional state. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of the cranial nerves are generated and organized. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions. + biological_process + GO:0021602 + cranial nerve morphogenesis + + + + + The process in which the anatomical structure of the cranial nerves are generated and organized. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to the cranial nerves. This process pertains to the initial formation of a structure from unspecified parts. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions. + biological_process + GO:0021603 + cranial nerve formation + + + + + The process that gives rise to the cranial nerves. This process pertains to the initial formation of a structure from unspecified parts. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for a cranial nerve to attain its fully functional state. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions. + biological_process + GO:0021605 + cranial nerve maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for a cranial nerve to attain its fully functional state. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the accessory nerve to attain its fully functional state. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve. + biological_process + CN XI maturation + spinal accessory nerve maturation + GO:0021606 + accessory nerve maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the accessory nerve to attain its fully functional state. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of the accessory nerve is generated and organized. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve. + biological_process + CN XI morphogenesis + GO:0021607 + accessory nerve morphogenesis + + + + + The process in which the anatomical structure of the accessory nerve is generated and organized. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to the accessory nerve. This process pertains to the initial formation of a structure from unspecified parts. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve. + biological_process + CN XI biosynthesis + CN XI formation + GO:0021608 + accessory nerve formation + + + + + The process that gives rise to the accessory nerve. This process pertains to the initial formation of a structure from unspecified parts. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of the facial nerve is generated and organized. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities. + biological_process + CN VII morphogenesis + GO:0021610 + facial nerve morphogenesis + + + + + The process in which the anatomical structure of the facial nerve is generated and organized. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to the facial nerve. This process pertains to the initial formation of a structure from unspecified parts. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities. + biological_process + CN VII biosynthesis + CN VII formation + GO:0021611 + facial nerve formation + + + + + The process that gives rise to the facial nerve. This process pertains to the initial formation of a structure from unspecified parts. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the facial nerve to attain its fully functional state. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities. + biological_process + CN VII maturation + GO:0021613 + facial nerve maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the facial nerve to attain its fully functional state. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the glossopharyngeal nerve to attain its fully functional state. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion. + biological_process + CN IX maturation + GO:0021614 + glossopharyngeal nerve maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the glossopharyngeal nerve to attain its fully functional state. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of the glossopharyngeal nerve is generated and organized. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion. + biological_process + CN IX morphogenesis + GO:0021615 + glossopharyngeal nerve morphogenesis + + + + + The process in which the anatomical structure of the glossopharyngeal nerve is generated and organized. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to the glossopharyngeal nerve. This process pertains to the initial formation of a structure from unspecified parts. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion. + biological_process + CN IX biosynthesis + CN IX formation + GO:0021616 + glossopharyngeal nerve formation + + + + + The process that gives rise to the glossopharyngeal nerve. This process pertains to the initial formation of a structure from unspecified parts. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of the hypoglossal nerve is generated and organized. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue. + biological_process + CN XII morphogenesis + GO:0021618 + hypoglossal nerve morphogenesis + + + + + The process in which the anatomical structure of the hypoglossal nerve is generated and organized. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the hypoglossal nerve to attain its fully functional state. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue. + biological_process + CN XII maturation + GO:0021619 + hypoglossal nerve maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the hypoglossal nerve to attain its fully functional state. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to the hypoglossal nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue. + biological_process + CN XII biosynthesis + CN XII formation + GO:0021620 + hypoglossal nerve formation + + + + + The process that gives rise to the hypoglossal nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of the oculomotor nerve is generated and organized. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle. + biological_process + CN III morphogenesis + GO:0021622 + oculomotor nerve morphogenesis + + + + + The process in which the anatomical structure of the oculomotor nerve is generated and organized. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to the oculomotor nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle. + biological_process + CN III biosynthesis + CN III formation + GO:0021623 + oculomotor nerve formation + + + + + The process that gives rise to the oculomotor nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the oculomotor nerve to attain its fully functional state. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle. + biological_process + CN III maturation + GO:0021625 + oculomotor nerve maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the oculomotor nerve to attain its fully functional state. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the central nervous system to attain its fully functional state. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. + biological_process + GO:0021626 + central nervous system maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the central nervous system to attain its fully functional state. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0582227089 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of the olfactory nerve is generated and organized. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem. + biological_process + CN I morphogenesis + GO:0021627 + olfactory nerve morphogenesis + + + + + The process in which the anatomical structure of the olfactory nerve is generated and organized. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to the olfactory nerve. This process pertains to the initial formation of a structure from unspecified parts. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem. + biological_process + CN I biosynthesis + CN I formation + GO:0021628 + olfactory nerve formation + + + + + The process that gives rise to the olfactory nerve. This process pertains to the initial formation of a structure from unspecified parts. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the olfactory nerve to attain its fully functional state. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem. + CN I maturation + biological_process + GO:0021630 + olfactory nerve maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the olfactory nerve to attain its fully functional state. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of the optic nerve is generated and organized. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain. + biological_process + CN II morphogenesis + GO:0021631 + optic nerve morphogenesis + + + + + The process in which the anatomical structure of the optic nerve is generated and organized. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the optic nerve to attain its fully functional state. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain. + CN II maturation + biological_process + GO:0021632 + optic nerve maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the optic nerve to attain its fully functional state. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to the optic nerve. This process pertains to the initial formation of a structure from unspecified parts. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain. + biological_process + CN II biosynthesis + CN II formation + GO:0021634 + optic nerve formation + + + + + The process that gives rise to the optic nerve. This process pertains to the initial formation of a structure from unspecified parts. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the trigeminal nerve to attain its fully functional state. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae. + biological_process + CN V maturation + GO:0021635 + trigeminal nerve maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the trigeminal nerve to attain its fully functional state. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of the trigeminal nerve is generated and organized. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae. + biological_process + CN V morphogenesis + GO:0021636 + trigeminal nerve morphogenesis + + + + + The process in which the anatomical structure of the trigeminal nerve is generated and organized. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to the trigeminal nerve. This process pertains to the initial formation of a structure from unspecified parts. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae. + biological_process + CN V biosynthesis + CN V formation + GO:0021638 + trigeminal nerve formation + + + + + The process that gives rise to the trigeminal nerve. This process pertains to the initial formation of a structure from unspecified parts. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of the trochlear nerve is generated and organized. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle. + biological_process + CH IV morphogenesis + GO:0021639 + trochlear nerve morphogenesis + + + + + The process in which the anatomical structure of the trochlear nerve is generated and organized. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the trochlear nerve to attain its fully functional state. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle. + biological_process + CN IV maturation + GO:0021640 + trochlear nerve maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the trochlear nerve to attain its fully functional state. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to the trochlear nerve. This process pertains to the initial formation of a structure from unspecified parts. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle. + biological_process + CN IV biosynthesis + CN IV formation + GO:0021642 + trochlear nerve formation + + + + + The process that gives rise to the trochlear nerve. This process pertains to the initial formation of a structure from unspecified parts. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the vagus nerve to attain its fully functional state. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis. + biological_process + CN X maturation + GO:0021643 + vagus nerve maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the vagus nerve to attain its fully functional state. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of the vagus nerve is generated and organized. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis. + biological_process + CN X morphogenesis + GO:0021644 + vagus nerve morphogenesis + + + + + The process in which the anatomical structure of the vagus nerve is generated and organized. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to the vagus nerve. This process pertains to the initial formation of a structure from unspecified parts. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis. + biological_process + CN X biosynthesis + CN X formation + GO:0021646 + vagus nerve formation + + + + + The process that gives rise to the vagus nerve. This process pertains to the initial formation of a structure from unspecified parts. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the vestibulocochlear nerve to attain its fully functional state. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea. + biological_process + CN VIII maturation + auditory nerve maturation + GO:0021647 + vestibulocochlear nerve maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the vestibulocochlear nerve to attain its fully functional state. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of the vestibulocochlear nerve is generated and organized. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea. + biological_process + CN VIII morphogenesis + GO:0021648 + vestibulocochlear nerve morphogenesis + + + + + The process in which the anatomical structure of the vestibulocochlear nerve is generated and organized. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to the vestibulocochlear nerve. This process pertains to the initial formation of a structure from unspecified parts. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea. + biological_process + CN VII formation + GO:0021650 + vestibulocochlear nerve formation + + + + + The process that gives rise to the vestibulocochlear nerve. This process pertains to the initial formation of a structure from unspecified parts. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of rhombomere 1 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. + biological_process + GO:0021651 + rhombomere 1 morphogenesis + + + + + The process in which the anatomical structure of rhombomere 1 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to rhombomere 1. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. + biological_process + GO:0021652 + rhombomere 1 formation + + + + + The process that gives rise to rhombomere 1. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to a rhombomere boundary. This process pertains to the initial formation of a boundary delimiting a rhombomere. Rhombomeres are transverse segments of the developing rhombencephalon that are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. + biological_process + GO:0021654 + rhombomere boundary formation + + + + + The process that gives rise to a rhombomere boundary. This process pertains to the initial formation of a boundary delimiting a rhombomere. Rhombomeres are transverse segments of the developing rhombencephalon that are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of rhombomere 2 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. + biological_process + GO:0021655 + rhombomere 2 morphogenesis + + + + + The process in which the anatomical structure of rhombomere 2 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to rhombomere 2. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. + biological_process + GO:0021657 + rhombomere 2 formation + + + + + The process that gives rise to rhombomere 2. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of rhombomere 3 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. + biological_process + GO:0021658 + rhombomere 3 morphogenesis + + + + + The process in which the anatomical structure of rhombomere 3 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to rhombomere 3. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. + biological_process + GO:0021660 + rhombomere 3 formation + + + + + The process that gives rise to rhombomere 3. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of rhombomere 4 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. + biological_process + GO:0021661 + rhombomere 4 morphogenesis + + + + + The process in which the anatomical structure of rhombomere 4 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to rhombomere 4. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. + biological_process + GO:0021663 + rhombomere 4 formation + + + + + The process that gives rise to rhombomere 4. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of rhombomere 5 are generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. + biological_process + GO:0021664 + rhombomere 5 morphogenesis + + + + + The process in which the anatomical structures of rhombomere 5 are generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to rhombomere 5. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. + biological_process + GO:0021666 + rhombomere 5 formation + + + + + The process that gives rise to rhombomere 5. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of rhombomere 6 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. + biological_process + GO:0021667 + rhombomere 6 morphogenesis + + + + + The process in which the anatomical structure of rhombomere 6 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to rhombomere 6. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. + biological_process + GO:0021669 + rhombomere 6 formation + + + + + The process that gives rise to rhombomere 6. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the lateral ventricles over time, from the formation to the mature structure. The two lateral ventricles are a cavity in each of the cerebral hemispheres derived from the cavity of the embryonic neural tube. They are separated from each other by the septum pellucidum, and each communicates with the third ventricle by the foramen of Monro, through which also the choroid plexuses of the lateral ventricles become continuous with that of the third ventricle. + biological_process + GO:0021670 + lateral ventricle development + + + + + The process whose specific outcome is the progression of the lateral ventricles over time, from the formation to the mature structure. The two lateral ventricles are a cavity in each of the cerebral hemispheres derived from the cavity of the embryonic neural tube. They are separated from each other by the septum pellucidum, and each communicates with the third ventricle by the foramen of Monro, through which also the choroid plexuses of the lateral ventricles become continuous with that of the third ventricle. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of rhombomere 7 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. + biological_process + GO:0021671 + rhombomere 7 morphogenesis + + + + + The process in which the anatomical structure of rhombomere 7 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to rhombomere 7. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. + biological_process + GO:0021673 + rhombomere 7 formation + + + + + The process that gives rise to rhombomere 7. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of rhombomere 8 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. + biological_process + GO:0021674 + rhombomere 8 morphogenesis + + + + + The process in which the anatomical structure of rhombomere 8 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a nerve over time, from its formation to the mature structure. + biological_process + GO:0021675 + nerve development + + + + + The process whose specific outcome is the progression of a nerve over time, from its formation to the mature structure. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to rhombomere 8. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. + biological_process + GO:0021677 + rhombomere 8 formation + + + + + The process that gives rise to rhombomere 8. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the third ventricle over time, from its formation to the mature structure. The third ventricle is the narrow cleft inferior to the corpus callosum, within the diencephalon, between the paired thalami. Its floor is formed by the hypothalamus, its anterior wall by the lamina terminalis, and its roof by ependyma, and it communicates with the fourth ventricle by the cerebral aqueduct, and with the lateral ventricles by the interventricular foramina. + biological_process + GO:0021678 + third ventricle development + + + + + The process whose specific outcome is the progression of the third ventricle over time, from its formation to the mature structure. The third ventricle is the narrow cleft inferior to the corpus callosum, within the diencephalon, between the paired thalami. Its floor is formed by the hypothalamus, its anterior wall by the lamina terminalis, and its roof by ependyma, and it communicates with the fourth ventricle by the cerebral aqueduct, and with the lateral ventricles by the interventricular foramina. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the cerebellar molecular layer nerve over time, from its formation to the mature structure. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells. + biological_process + GO:0021679 + cerebellar molecular layer development + + + + + The process whose specific outcome is the progression of the cerebellar molecular layer nerve over time, from its formation to the mature structure. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the cerebellar Purkinje cell layer over time, from its formation to the mature structure. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells. + biological_process + GO:0021680 + cerebellar Purkinje cell layer development + + + + + The process whose specific outcome is the progression of the cerebellar Purkinje cell layer over time, from its formation to the mature structure. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the cerebellar granule layer over time, from its formation to the mature structure. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer. + biological_process + GO:0021681 + cerebellar granular layer development + + + + + The process whose specific outcome is the progression of the cerebellar granule layer over time, from its formation to the mature structure. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for a nerve to attain its fully functional state. + biological_process + GO:0021682 + nerve maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for a nerve to attain its fully functional state. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of the cerebellar granular layer is generated and organized. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer. + biological_process + GO:0021683 + cerebellar granular layer morphogenesis + + + + + The process in which the anatomical structure of the cerebellar granular layer is generated and organized. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to the cerebellar granule layer. This process pertains to the initial formation of a structure from unspecified parts. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer. + biological_process + GO:0021684 + cerebellar granular layer formation + + + + + The process that gives rise to the cerebellar granule layer. This process pertains to the initial formation of a structure from unspecified parts. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar granular layer to attain its fully functional state. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer. + biological_process + GO:0021686 + cerebellar granular layer maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar granular layer to attain its fully functional state. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of the cerebellar molecular layer is generated and organized. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells. + biological_process + GO:0021687 + cerebellar molecular layer morphogenesis + + + + + The process in which the anatomical structure of the cerebellar molecular layer is generated and organized. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to the cerebellar molecular layer. This process pertains to the initial formation of a structure from unspecified parts. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells. + biological_process + GO:0021688 + cerebellar molecular layer formation + + + + + The process that gives rise to the cerebellar molecular layer. This process pertains to the initial formation of a structure from unspecified parts. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar molecular layer to attain its fully functional state. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells. + biological_process + GO:0021690 + cerebellar molecular layer maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar molecular layer to attain its fully functional state. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar Purkinje cell layer to attain its fully functional state. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells. + biological_process + GO:0021691 + cerebellar Purkinje cell layer maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar Purkinje cell layer to attain its fully functional state. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of the cerebellar Purkinje cell layer is generated and organized. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells. + biological_process + GO:0021692 + cerebellar Purkinje cell layer morphogenesis + + + + + The process in which the anatomical structure of the cerebellar Purkinje cell layer is generated and organized. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to the cerebellar Purkinje cell layer. This process pertains to the initial formation of a structure from unspecified parts. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells. + biological_process + GO:0021694 + cerebellar Purkinje cell layer formation + + + + + The process that gives rise to the cerebellar Purkinje cell layer. This process pertains to the initial formation of a structure from unspecified parts. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the cerebellar cortex over time, from its formation to the mature structure. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function. + biological_process + GO:0021695 + cerebellar cortex development + + + + + The process whose specific outcome is the progression of the cerebellar cortex over time, from its formation to the mature structure. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of the cranial nerves are generated and organized. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function. + biological_process + GO:0021696 + cerebellar cortex morphogenesis + + + + + The process in which the anatomical structure of the cranial nerves are generated and organized. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to the cerebellar cortex. This process pertains to the initial formation of a structure from unspecified parts. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function. + biological_process + GO:0021697 + cerebellar cortex formation + + + + + The process that gives rise to the cerebellar cortex. This process pertains to the initial formation of a structure from unspecified parts. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar cortex to attain its fully functional state. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function. + biological_process + GO:0021699 + cerebellar cortex maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar cortex to attain its fully functional state. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure, cell or cellular component to attain its fully functional state. + biological_process + GO:0021700 + + developmental maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure, cell or cellular component to attain its fully functional state. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Golgi cell. Differentiation includes the processes involved in commitment of a neuroblast to a Golgi cell fate. A cerebellar Golgi cell is an inhibitory GABAergic interneuron found in the cerebellar cortex. + biological_process + GO:0021701 + cerebellar Golgi cell differentiation + + + + + The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Golgi cell. Differentiation includes the processes involved in commitment of a neuroblast to a Golgi cell fate. A cerebellar Golgi cell is an inhibitory GABAergic interneuron found in the cerebellar cortex. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + PMID:15157725 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Purkinje cell. Differentiation includes the processes involved in commitment of a neuroblast to a Purkinje cell fate. A Purkinje cell is an inhibitory GABAergic neuron found in the cerebellar cortex that projects to the deep cerebellar nuclei and brain stem. + biological_process + GO:0021702 + cerebellar Purkinje cell differentiation + + + + + The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Purkinje cell. Differentiation includes the processes involved in commitment of a neuroblast to a Purkinje cell fate. A Purkinje cell is an inhibitory GABAergic neuron found in the cerebellar cortex that projects to the deep cerebellar nuclei and brain stem. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + PMID:15157725 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the locus ceruleus over time, from its formation to the mature structure. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic. + locus caeruleus development + locus coeruleus development + biological_process + GO:0021703 + locus ceruleus development + + + + + The process whose specific outcome is the progression of the locus ceruleus over time, from its formation to the mature structure. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of the locus ceruleus is generated and organized. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic. + biological_process + GO:0021704 + locus ceruleus morphogenesis + + + + + The process in which the anatomical structure of the locus ceruleus is generated and organized. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to the locus ceruleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic. + biological_process + GO:0021705 + locus ceruleus formation + + + + + The process that gives rise to the locus ceruleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the locus ceruleus to attain its fully functional state. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic. + biological_process + GO:0021706 + locus ceruleus maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the locus ceruleus to attain its fully functional state. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar granule cell. Differentiation includes the processes involved in commitment of a neuroblast to a granule cell fate. A granule cell is a glutamatergic interneuron found in the cerebellar cortex. + biological_process + GO:0021707 + cerebellar granule cell differentiation + + + + + The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar granule cell. Differentiation includes the processes involved in commitment of a neuroblast to a granule cell fate. A granule cell is a glutamatergic interneuron found in the cerebellar cortex. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + PMID:15157725 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the inferior olivary nucleus over time, from its formation to the mature structure. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements. + biological_process + inferior olive development + GO:0021713 + inferior olivary nucleus development + + + + + The process whose specific outcome is the progression of the inferior olivary nucleus over time, from its formation to the mature structure. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of the inferior olivary nucleus is generated and organized. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements. + biological_process + inferior olive morphogenesis + GO:0021714 + inferior olivary nucleus morphogenesis + + + + + The process in which the anatomical structure of the inferior olivary nucleus is generated and organized. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to the inferior olivary nucleus. This process pertains to the initial formation of a structure from unspecified parts. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements. + biological_process + inferior olive biosynthesis + inferior olive formation + GO:0021715 + inferior olivary nucleus formation + + + + + The process that gives rise to the inferior olivary nucleus. This process pertains to the initial formation of a structure from unspecified parts. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the inferior olivary nucleus to attain its fully functional state. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements. + biological_process + inferior olive maturation + GO:0021717 + inferior olivary nucleus maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the inferior olivary nucleus to attain its fully functional state. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the superior olivary nucleus over time, from its formation to the mature structure. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound. + biological_process + superior olive development + GO:0021718 + superior olivary nucleus development + + + + + The process whose specific outcome is the progression of the superior olivary nucleus over time, from its formation to the mature structure. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of the superior olivary nucleus is generated and organized. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound. + biological_process + superior olive morphogenesis + GO:0021719 + superior olivary nucleus morphogenesis + + + + + The process in which the anatomical structure of the superior olivary nucleus is generated and organized. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to the superior olivary nucleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound. + biological_process + GO:0021720 + superior olivary nucleus formation + + + + + The process that gives rise to the superior olivary nucleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the superior olivary nucleus to attain its fully functional state. The superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound. + biological_process + superior olive maturation + GO:0021722 + superior olivary nucleus maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the superior olivary nucleus to attain its fully functional state. The superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the medullary reticular formation over time, from its formation to the mature structure. The medullary reticular formation is a series of brain nuclei located in the medulla oblongata. + rhombencephalic reticular formation development + biological_process + GO:0021723 + medullary reticular formation development + + + + + The process whose specific outcome is the progression of the medullary reticular formation over time, from its formation to the mature structure. The medullary reticular formation is a series of brain nuclei located in the medulla oblongata. + GOC:cjm + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + Wikipedia:Rhombencephalon + http://www.brainspan.org + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the inferior raphe nucleus over time, from its formation to the mature structure. + inferior central nucleus development + posterior raphe nucleus development + biological_process + GO:0021724 + inferior raphe nucleus development + + + + + The process whose specific outcome is the progression of the inferior raphe nucleus over time, from its formation to the mature structure. + GOC:cjm + GOC:cls + GOC:curators + GOC:cvs + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + PMID:19003874 + ZFA:0000366 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the superior raphe nucleus over time, from its formation to the mature structure. + anterior raphe nucleus development + superior central nucleus development + biological_process + GO:0021725 + superior raphe nucleus development + + + + + The process whose specific outcome is the progression of the superior raphe nucleus over time, from its formation to the mature structure. + GOC:cjm + GOC:cls + GOC:curators + GOC:cvs + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + PMID:19003874 + ZFA:0000440 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the lateral reticular nucleus over time, from its formation to the mature structure. + biological_process + GO:0021726 + lateral reticular nucleus development + + + + + The process whose specific outcome is the progression of the lateral reticular nucleus over time, from its formation to the mature structure. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the intermediate reticular formation over time, from its formation to the mature structure. + intermediate reticular nucleus development + biological_process + GO:0021727 + intermediate reticular formation development + + + + + The process whose specific outcome is the progression of the intermediate reticular formation over time, from its formation to the mature structure. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + intermediate reticular nucleus development + http://www.brainspan.org + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the inferior reticular formation over time, from its formation to the mature structure. + biological_process + GO:0021728 + inferior reticular formation development + + + + + The process whose specific outcome is the progression of the inferior reticular formation over time, from its formation to the mature structure. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the superior reticular formation over time, from its formation to the mature structure. + biological_process + GO:0021729 + superior reticular formation development + + + + + The process whose specific outcome is the progression of the superior reticular formation over time, from its formation to the mature structure. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the trigeminal sensory nucleus over time, from its formation to the mature structure. + biological_process + GO:0021730 + Note that this term was placed as a child of 'brain development' because the nucleus spans multiple brain regions from midbrain to spinal cord. + trigeminal sensory nucleus development + + + + + The process whose specific outcome is the progression of the trigeminal sensory nucleus over time, from its formation to the mature structure. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the trigeminal motor nucleus over time, from its formation to the mature structure. + biological_process + GO:0021731 + trigeminal motor nucleus development + + + + + The process whose specific outcome is the progression of the trigeminal motor nucleus over time, from its formation to the mature structure. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate. + biological_process + MHB maturation + isthmus maturation + GO:0021732 + midbrain-hindbrain boundary maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + PMID:15541513 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the dentate nucleus over time, from its formation to the mature structure. + biological_process + GO:0021735 + dentate nucleus development + + + + + The process whose specific outcome is the progression of the dentate nucleus over time, from its formation to the mature structure. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the globose nucleus over time, from its formation to the mature structure. + biological_process + GO:0021736 + globose nucleus development + + + + + The process whose specific outcome is the progression of the globose nucleus over time, from its formation to the mature structure. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the emboliform nucleus over time, from its formation to the mature structure. + biological_process + GO:0021737 + emboliform nucleus development + + + + + The process whose specific outcome is the progression of the emboliform nucleus over time, from its formation to the mature structure. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the fastigial nucleus over time, from its formation to the mature structure. + biological_process + GO:0021738 + fastigial nucleus development + + + + + The process whose specific outcome is the progression of the fastigial nucleus over time, from its formation to the mature structure. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the mesencephalic trigeminal nucleus over time, from its formation to the mature structure. + biological_process + GO:0021739 + mesencephalic trigeminal nucleus development + + + + + The process whose specific outcome is the progression of the mesencephalic trigeminal nucleus over time, from its formation to the mature structure. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the pontine nucleus over time, from its formation to the mature structure. + pontine nucleus development + biological_process + GO:0021740 + Note that this term was placed as a child of 'brain development' because the nucleus spans multiple brain regions. + principal sensory nucleus of trigeminal nerve development + + + + + The process whose specific outcome is the progression of the pontine nucleus over time, from its formation to the mature structure. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + pontine nucleus development + GOC:dph + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the spinal trigeminal nucleus over time, from its formation to the mature structure. + biological_process + GO:0021741 + spinal trigeminal nucleus development + + + + + The process whose specific outcome is the progression of the spinal trigeminal nucleus over time, from its formation to the mature structure. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the abducens nucleus over time, from its formation to the mature structure. + biological_process + GO:0021742 + abducens nucleus development + + + + + The process whose specific outcome is the progression of the abducens nucleus over time, from its formation to the mature structure. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the hypoglossal nucleus over time, from its formation to the mature structure. + biological_process + GO:0021743 + hypoglossal nucleus development + + + + + The process whose specific outcome is the progression of the hypoglossal nucleus over time, from its formation to the mature structure. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the dorsal motor nucleus of the vagus nerve over time, from its formation to the mature structure. + biological_process + GO:0021744 + dorsal motor nucleus of vagus nerve development + + + + + The process whose specific outcome is the progression of the dorsal motor nucleus of the vagus nerve over time, from its formation to the mature structure. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the nucleus ambiguus over time, from its formation to the mature structure. + biological_process + GO:0021745 + nucleus ambiguus development + + + + + The process whose specific outcome is the progression of the nucleus ambiguus over time, from its formation to the mature structure. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the solitary nucleus over time, from its formation to the mature structure. + biological_process + GO:0021746 + solitary nucleus development + + + + + The process whose specific outcome is the progression of the solitary nucleus over time, from its formation to the mature structure. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the cochlear nucleus over time, from its formation to the mature structure. + biological_process + GO:0021747 + cochlear nucleus development + + + + + The process whose specific outcome is the progression of the cochlear nucleus over time, from its formation to the mature structure. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the dorsal cochlear nucleus over time, from its formation to the mature structure. + biological_process + GO:0021748 + dorsal cochlear nucleus development + + + + + The process whose specific outcome is the progression of the dorsal cochlear nucleus over time, from its formation to the mature structure. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the ventral cochlear nucleus over time, from its formation to the mature structure. + biological_process + GO:0021749 + ventral cochlear nucleus development + + + + + The process whose specific outcome is the progression of the ventral cochlear nucleus over time, from its formation to the mature structure. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the vestibular nucleus over time, from its formation to the mature structure. + biological_process + GO:0021750 + vestibular nucleus development + + + + + The process whose specific outcome is the progression of the vestibular nucleus over time, from its formation to the mature structure. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + PMID:16221589 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a salivary nucleus over time, from its formation to the mature structure. + biological_process + GO:0021751 + salivary nucleus development + + + + + The process whose specific outcome is the progression of a salivary nucleus over time, from its formation to the mature structure. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the inferior salivary nucleus over time, from its formation to the mature structure. + biological_process + GO:0021752 + inferior salivary nucleus development + + + + + The process whose specific outcome is the progression of the inferior salivary nucleus over time, from its formation to the mature structure. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the superior salivary nucleus over time, from its formation to the mature structure. + biological_process + GO:0021753 + superior salivary nucleus development + + + + + The process whose specific outcome is the progression of the superior salivary nucleus over time, from its formation to the mature structure. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the facial nucleus over time, from its formation to the mature structure. + biological_process + GO:0021754 + facial nucleus development + + + + + The process whose specific outcome is the progression of the facial nucleus over time, from its formation to the mature structure. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the striatum over time from its initial formation until its mature state. The striatum is a region of the forebrain consisting of the caudate nucleus, putamen and fundus striati. + neostriatum development + striate nucleus development + biological_process + GO:0021756 + striatum development + + + + + The progression of the striatum over time from its initial formation until its mature state. The striatum is a region of the forebrain consisting of the caudate nucleus, putamen and fundus striati. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0878937420 + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the caudate nucleus over time from its initial formation until its mature state. The caudate nucleus is the C-shaped structures of the striatum containing input neurons involved with control of voluntary movement in the brain. + biological_process + GO:0021757 + caudate nucleus development + + + + + The progression of the caudate nucleus over time from its initial formation until its mature state. The caudate nucleus is the C-shaped structures of the striatum containing input neurons involved with control of voluntary movement in the brain. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0878937420 + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the putamen over time from its initial formation until its mature state. The putamen is the lens-shaped basal ganglion involved with control of voluntary movement in the brain. + biological_process + GO:0021758 + putamen development + + + + + The progression of the putamen over time from its initial formation until its mature state. The putamen is the lens-shaped basal ganglion involved with control of voluntary movement in the brain. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0878937420 + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the globus pallidus over time from its initial formation until its mature state. The globus pallidus is one of the basal ganglia involved with control of voluntary movement in the brain. + pallidum development + biological_process + GO:0021759 + globus pallidus development + + + + + The progression of the globus pallidus over time from its initial formation until its mature state. The globus pallidus is one of the basal ganglia involved with control of voluntary movement in the brain. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0878937420 + + + + + pallidum development + PMID:16271465 + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the limbic system over time from its initial formation until its mature state. The limbic system is a collection of structures in the brain involved in emotion, motivation and emotional aspects of memory. + biological_process + GO:0021761 + limbic system development + + + + + The progression of the limbic system over time from its initial formation until its mature state. The limbic system is a collection of structures in the brain involved in emotion, motivation and emotional aspects of memory. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0878937420 + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the substantia nigra over time from its initial formation until its mature state. The substantia nigra is the layer of gray substance that separates the posterior parts of the cerebral peduncles (tegmentum mesencephali) from the anterior parts; it normally includes a posterior compact part with many pigmented cells (pars compacta) and an anterior reticular part whose cells contain little pigment (pars reticularis). + biological_process + GO:0021762 + substantia nigra development + + + + + The progression of the substantia nigra over time from its initial formation until its mature state. The substantia nigra is the layer of gray substance that separates the posterior parts of the cerebral peduncles (tegmentum mesencephali) from the anterior parts; it normally includes a posterior compact part with many pigmented cells (pars compacta) and an anterior reticular part whose cells contain little pigment (pars reticularis). + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0838580343 + ISBN:0878937420 + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the subthalamic nucleus over time from its initial formation until its mature state. The subthalamic nucleus is the lens-shaped nucleus located in the ventral part of the subthalamus on the inner aspect of the internal capsule that is concerned with the integration of somatic motor function. + biological_process + corpus luysi development + GO:0021763 + subthalamic nucleus development + + + + + The progression of the subthalamic nucleus over time from its initial formation until its mature state. The subthalamic nucleus is the lens-shaped nucleus located in the ventral part of the subthalamus on the inner aspect of the internal capsule that is concerned with the integration of somatic motor function. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0878937420 + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the amygdala over time from its initial formation until its mature state. The amygdala is an almond-shaped set of neurons in the medial temporal lobe of the brain that play a key role in processing emotions such as fear and pleasure. + biological_process + GO:0021764 + amygdala development + + + + + The progression of the amygdala over time from its initial formation until its mature state. The amygdala is an almond-shaped set of neurons in the medial temporal lobe of the brain that play a key role in processing emotions such as fear and pleasure. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0878937420 + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the cingulate gyrus over time from its initial formation until its mature state. The cingulate gyrus is a ridge in the cerebral cortex located dorsal to the corpus callosum. + biological_process + GO:0021765 + cingulate gyrus development + + + + + The progression of the cingulate gyrus over time from its initial formation until its mature state. The cingulate gyrus is a ridge in the cerebral cortex located dorsal to the corpus callosum. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0878937420 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the hippocampus over time from its initial formation until its mature state. + hippocampal formation development + biological_process + GO:0021766 + hippocampus development + + + + + The progression of the hippocampus over time from its initial formation until its mature state. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0878937420 + UBERON:0002421 + + + + + hippocampal formation development + ABA:HPF + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the mammillary body over time from its initial formation until its mature state. The mammillary body is a protrusion at the posterior end of the hypothalamus that contains hypothalamic nuclei. + biological_process + GO:0021767 + mammillary body development + + + + + The progression of the mammillary body over time from its initial formation until its mature state. The mammillary body is a protrusion at the posterior end of the hypothalamus that contains hypothalamic nuclei. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0878937420 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the nucleus accumbens over time from its initial formation until its mature state. The nucleus accumbens is a collection of pleomorphic cells in the caudal part of the anterior horn of the lateral ventricle, in the region of the olfactory tubercle, lying between the head of the caudate nucleus and the anterior perforated substance. It is part of the ventral striatum, a composite structure considered part of the basal ganglia. + ventral striatum development + accumbens nucleus development + biological_process + GO:0021768 + nucleus accumbens development + + + + + The progression of the nucleus accumbens over time from its initial formation until its mature state. The nucleus accumbens is a collection of pleomorphic cells in the caudal part of the anterior horn of the lateral ventricle, in the region of the olfactory tubercle, lying between the head of the caudate nucleus and the anterior perforated substance. It is part of the ventral striatum, a composite structure considered part of the basal ganglia. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0878937420 + + + + + accumbens nucleus development + GOC:dgh + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the orbitofrontal cortex over time from its initial formation until its mature state. The orbitofrontal cortex is a cerebral cortex region located in the frontal lobe. + biological_process + GO:0021769 + orbitofrontal cortex development + + + + + The progression of the orbitofrontal cortex over time from its initial formation until its mature state. The orbitofrontal cortex is a cerebral cortex region located in the frontal lobe. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0878937420 + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the parahippocampal gyrus over time from its initial formation until its mature state. The parahippocampal gyrus is a ridge in the cerebral cortex. + Wikipedia:parahippocampal_gyrus + hippocampal gyrus development + biological_process + GO:0021770 + parahippocampal gyrus development + + + + + The progression of the parahippocampal gyrus over time from its initial formation until its mature state. The parahippocampal gyrus is a ridge in the cerebral cortex. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0878937420 + + + + + hippocampal gyrus development + GOC:dgh + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the lateral geniculate nucleus over time from its initial formation until its mature state. The lateral geniculate nucleus is the primary processor of visual information received from the retina. + LGN development + biological_process + GO:0021771 + lateral geniculate nucleus development + + + + + The progression of the lateral geniculate nucleus over time from its initial formation until its mature state. The lateral geniculate nucleus is the primary processor of visual information received from the retina. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0878937420 + + + + + LGN development + GOC:dgh + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the olfactory bulb over time from its initial formation until its mature state. The olfactory bulb coordinates neuronal signaling involved in the perception of smell. It receives input from the sensory neurons and outputs to the olfactory cortex. + biological_process + GO:0021772 + olfactory bulb development + + + + + The progression of the olfactory bulb over time from its initial formation until its mature state. The olfactory bulb coordinates neuronal signaling involved in the perception of smell. It receives input from the sensory neurons and outputs to the olfactory cortex. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0878937420 + + + + + + + + + + + + + + + + + + + + + + + + + + The process aimed at the progression of a glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. + biological_process + GO:0021782 + glial cell development + + + + + The process aimed at the progression of a glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a preganglionic parasympathetic fiber over time, from its formation to the mature structure. A preganglionic parasympathetic fiber is a cholinergic axonal fiber projecting from the CNS to a parasympathetic ganglion. + biological_process + GO:0021783 + preganglionic parasympathetic fiber development + + + + + The process whose specific outcome is the progression of a preganglionic parasympathetic fiber over time, from its formation to the mature structure. A preganglionic parasympathetic fiber is a cholinergic axonal fiber projecting from the CNS to a parasympathetic ganglion. + GOC:cjm + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the postganglionic portion of the parasympathetic fiber over time, from its formation to the mature structure. The parasympathetic fiber is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia. + biological_process + GO:0021784 + postganglionic parasympathetic fiber development + + + + + The process whose specific outcome is the progression of the postganglionic portion of the parasympathetic fiber over time, from its formation to the mature structure. The parasympathetic fiber is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the thalamus changes over time, from its initial formation to its mature state. + biological_process + GO:0021794 + thalamus development + + + + + The process in which the thalamus changes over time, from its initial formation to its mature state. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + The orderly movement of cells from one site to another in the cerebral cortex. + biological_process + GO:0021795 + cerebral cortex cell migration + + + + + The orderly movement of cells from one site to another in the cerebral cortex. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + The migration of cells in the developing cerebral cortex in which cells move from the ventricular and/or subventricular zone toward the surface of the brain. + biological_process + GO:0021799 + cerebral cortex radially oriented cell migration + + + + + The migration of cells in the developing cerebral cortex in which cells move from the ventricular and/or subventricular zone toward the surface of the brain. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + PMID:12626695 + + + + + + + + + + + + + + + The radial migration of neuronal or glial precursor cells along radial glial cells during the development of the cerebral cortex. + cerebral cortex radial glia guided migration + cerebral cortex radial glia-dependent cell migration + biological_process + glial-guided locomotion + GO:0021801 + cerebral cortex radial glia-guided migration + + + + + The radial migration of neuronal or glial precursor cells along radial glial cells during the development of the cerebral cortex. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + PMID:12626695 + + + + + glial-guided locomotion + PMID:12626695 + + + + + + + + + + + + + + + + + + + The movement of a cell along the process of a radial glial cell involved in cerebral cortex glial-mediated radial migration. + cell locomotion involved in cerebral cortex glial-mediated radial migration + biological_process + cell locomotion involved in cerebral cortex radial glia guided migration + GO:0021814 + cell motility involved in cerebral cortex radial glia guided migration + + + + + The movement of a cell along the process of a radial glial cell involved in cerebral cortex glial-mediated radial migration. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + PMID:12626695 + + + + + cell locomotion involved in cerebral cortex glial-mediated radial migration + GOC:dph + + + + + cell locomotion involved in cerebral cortex radial glia guided migration + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + Rearrangements of the microtubule cytoskeleton that contribute to the movement of cells along radial glial cells as a component of the process of cerebral cortex glial-mediated radial migration. + modulation of microtubule cytoskeleton involved in cerebral cortex glial-mediated radial migration + biological_process + GO:0021815 + modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration + + + + + Rearrangements of the microtubule cytoskeleton that contribute to the movement of cells along radial glial cells as a component of the process of cerebral cortex glial-mediated radial migration. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + PMID:12626695 + + + + + modulation of microtubule cytoskeleton involved in cerebral cortex glial-mediated radial migration + GOC:dph + + + + + + + + + + + + + + + + The detachment of cells from radial glial fibers at the appropriate time when they cease to migrate and form distinct layer in the cerebral cortex. + biological_process + cerebral cortex lamination + GO:0021819 + layer formation in cerebral cortex + + + + + The detachment of cells from radial glial fibers at the appropriate time when they cease to migrate and form distinct layer in the cerebral cortex. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + PMID:12626695 + + + + + cerebral cortex lamination + PMID:12626695 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The intracellular signaling pathway that results in the cessation of cell movement involved in lamination of the cerebral cortex. + down regulation of cell locomotion involved in cerebral cortex glial-mediated radial cell migration + down-regulation of cell locomotion involved in cerebral cortex glial-mediated radial cell migration + downregulation of cell locomotion involved in cerebral cortex glial-mediated radial cell migration + negative regulation of cell locomotion involved in cerebral cortex glial-mediated radial migration + inhibition of cell locomotion involved in cerebral cortex glial-mediated radial cell migration + biological_process + negative regulation of cell locomotion involved in cerebral cortex radial glia guided migration + GO:0021822 + negative regulation of cell motility involved in cerebral cortex radial glia guided migration + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + The intracellular signaling pathway that results in the cessation of cell movement involved in lamination of the cerebral cortex. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GOC:tb + GO_REF:0000021 + PMID:12626695 + + + + + negative regulation of cell locomotion involved in cerebral cortex glial-mediated radial migration + GOC:dph + + + + + negative regulation of cell locomotion involved in cerebral cortex radial glia guided migration + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + + + + + + + The creation of greater cell numbers in the forebrain due to cell division of progenitor cells. + biological_process + GO:0021846 + cell proliferation in forebrain + + + + + The creation of greater cell numbers in the forebrain due to cell division of progenitor cells. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + The division of neuroblasts in the subpallium area of the forebrain. The interneuron precursors that these cells give rise to include GABAergic interneurons and will migrate tangentially. + neuroblast division in the ventral telencephalon + biological_process + GO:0021848 + neuroblast division in subpallium + + + + + The division of neuroblasts in the subpallium area of the forebrain. The interneuron precursors that these cells give rise to include GABAergic interneurons and will migrate tangentially. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + PMID:12626695 + + + + + neuroblast division in the ventral telencephalon + PMID:16226447 + + + + + + + + + + + + + + + + + + + + + + + + + The division of neuroblasts in the subventricular zone of the forebrain. The interneuron precursors that these cells give rise to include adult olfactory bulb interneurons and migrate tangentially. + biological_process + GO:0021849 + neuroblast division in subventricular zone + + + + + The division of neuroblasts in the subventricular zone of the forebrain. The interneuron precursors that these cells give rise to include adult olfactory bulb interneurons and migrate tangentially. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + PMID:12626695 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The migration of a pyramidal neuron precursor from the ventricular zone to the correct layer of the cerebral cortex. + https://github.com/geneontology/go-ontology/issues/21476 + pyramidal neuron migration + biological_process + projection neuron migration + GO:0021852 + pyramidal neuron migration to cerebral cortex + + + + + The migration of a pyramidal neuron precursor from the ventricular zone to the correct layer of the cerebral cortex. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + PMID:12626695 + PMID:22192824 + + + + + projection neuron migration + PMID:12626695 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the hypothalamus region of the forebrain, from its initial formation to its mature state. + biological_process + GO:0021854 + hypothalamus development + + + + + The progression of the hypothalamus region of the forebrain, from its initial formation to its mature state. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + The process in which a neuroblast or one of its progeny commits to a pyramidal neuron fate, migrates from the ventricular zone to the appropriate layer in the cortex and develops into a mature neuron. + projection neuron differentiation + biological_process + GO:0021859 + pyramidal neuron differentiation + + + + + The process in which a neuroblast or one of its progeny commits to a pyramidal neuron fate, migrates from the ventricular zone to the appropriate layer in the cortex and develops into a mature neuron. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + projection neuron differentiation + PMID:16226447 + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of a pyramidal neuron from its initial formation to its mature state. + projection neuron development + biological_process + GO:0021860 + pyramidal neuron development + + + + + The progression of a pyramidal neuron from its initial formation to its mature state. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + projection neuron development + PMID:16226447 + + + + + + + + + + + + + + + The process in which nerve cells are generated in the forebrain. This includes the production of neuroblasts from and their differentiation into neurons. + generation of neurons in forebrain + biological_process + GO:0021872 + forebrain generation of neurons + + + + + The process in which nerve cells are generated in the forebrain. This includes the production of neuroblasts from and their differentiation into neurons. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of a neuron that will reside in the forebrain. + biological_process + GO:0021879 + forebrain neuron differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized features of a neuron that will reside in the forebrain. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + PMID:16226447 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a neuron that resides in the forebrain, from its initial commitment to its fate, to the fully functional differentiated cell. + biological_process + GO:0021884 + forebrain neuron development + + + + + The process whose specific outcome is the progression of a neuron that resides in the forebrain, from its initial commitment to its fate, to the fully functional differentiated cell. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + The orderly movement of a cell from one site to another at least one of which is located in the forebrain. + biological_process + GO:0021885 + forebrain cell migration + + + + + The orderly movement of a cell from one site to another at least one of which is located in the forebrain. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + The process in which the neural tube is divided into specific regions along the rostrocaudal axis. + biological_process + anterior-posterior neural tube patterning + GO:0021903 + rostrocaudal neural tube patterning + + + + + The process in which the neural tube is divided into specific regions along the rostrocaudal axis. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + PMID:11262869 + + + + + anterior-posterior neural tube patterning + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the creation of the forebrain-midbrain boundary. + biological_process + GO:0021905 + forebrain-midbrain boundary formation + + + + + The process whose specific outcome is the creation of the forebrain-midbrain boundary. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + PMID:11262869 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the formation of the hindbrain-spinal cord boundary. + biological_process + GO:0021906 + hindbrain-spinal cord boundary formation + + + + + The process whose specific outcome is the formation of the hindbrain-spinal cord boundary. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + PMID:11262869 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the neural tube over time, from its formation to the mature structure. The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium. + biological_process + GO:0021915 + neural tube development + + + + + The process whose specific outcome is the progression of the neural tube over time, from its formation to the mature structure. The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process that modulates the frequency, rate or extent of cell proliferation in the dorsal spinal cord. + biological_process + GO:0021921 + regulation of cell proliferation in dorsal spinal cord + + + + + The process that modulates the frequency, rate or extent of cell proliferation in the dorsal spinal cord. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells in a different central nervous system region. + central nervous system axon tract development + biological_process + GO:0021952 + central nervous system projection neuron axonogenesis + + + + + Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells in a different central nervous system region. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + central nervous system axon tract development + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the central nervous system. + biological_process + GO:0021953 + central nervous system neuron differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the central nervous system. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a neuron whose cell body is located in the central nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron. + biological_process + GO:0021954 + central nervous system neuron development + + + + + The process whose specific outcome is the progression of a neuron whose cell body is located in the central nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + Generation of a long process from a neuron whose cell body resides in the central nervous system. The process carries efferent (outgoing) action potentials from the cell body towards target cells. + biological_process + GO:0021955 + central nervous system neuron axonogenesis + + + + + Generation of a long process from a neuron whose cell body resides in the central nervous system. The process carries efferent (outgoing) action potentials from the cell body towards target cells. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + Generation of a long process of a pyramidal cell, that carries efferent (outgoing) action potentials from the cell body in cerebral cortex layer V towards target cells in the gray matter of the spinal cord. This axonal process is a member of those that make up the corticospinal tract. + CST axonogenesis + corticospinal tract axonogenesis + biological_process + GO:0021957 + corticospinal tract morphogenesis + + + + + Generation of a long process of a pyramidal cell, that carries efferent (outgoing) action potentials from the cell body in cerebral cortex layer V towards target cells in the gray matter of the spinal cord. This axonal process is a member of those that make up the corticospinal tract. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + PMID:9878731 + + + + + CST axonogenesis + GOC:dph + PMID:9878731 + + + + + corticospinal tract axonogenesis + GOC:dph + PMID:9878731 + + + + + + + + + + + + + + + + + + + + Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the dorsal root ganglion towards target cells in the medulla. This axonal process is a member of those that make up the gracilis tract, a group of axons that are from neurons involved in proprioception from the lower trunk and lower limb. + tract of Goll morphogenesis + biological_process + GO:0021958 + gracilis tract morphogenesis + + + + + Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the dorsal root ganglion towards target cells in the medulla. This axonal process is a member of those that make up the gracilis tract, a group of axons that are from neurons involved in proprioception from the lower trunk and lower limb. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + PMID:12867698 + + + + + tract of Goll morphogenesis + PMID:12867698 + + + + + + + + + + + + + + + + + + + + Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the dorsal root ganglion towards target cells in the medulla. This axonal process is a member of those that make up the cuneatus tract, a group of axons that are from neurons involved in proprioception from the upper trunk and upper limb. + tract of Burdach morphogenesis + biological_process + GO:0021959 + cuneatus tract morphogenesis + + + + + Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the dorsal root ganglion towards target cells in the medulla. This axonal process is a member of those that make up the cuneatus tract, a group of axons that are from neurons involved in proprioception from the upper trunk and upper limb. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + PMID:12867698 + + + + + tract of Burdach morphogenesis + PMID:12867698 + + + + + + + + + + + + + + + + + + + + + + + + + + Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in one half of the cerebral cortex towards target cells in the contralateral half. This axonal process is a member of those that make up the anterior commissure, a small midline fiber tract that lies at the anterior end of the corpus callosum. + biological_process + GO:0021960 + anterior commissure morphogenesis + + + + + Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in one half of the cerebral cortex towards target cells in the contralateral half. This axonal process is a member of those that make up the anterior commissure, a small midline fiber tract that lies at the anterior end of the corpus callosum. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0878937420 + + + + + + + + + + + + + + + + + + + + Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the midbrain towards target cells in the diencephalon. + biological_process + GO:0021961 + posterior commissure morphogenesis + + + + + Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the midbrain towards target cells in the diencephalon. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the vestibular nucleus of the pons towards target cells in the spinal cord. + biological_process + GO:0021962 + vestibulospinal tract morphogenesis + + + + + Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the vestibular nucleus of the pons towards target cells in the spinal cord. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the spinal cord towards target cells in the thalamus. This axonal process is a member of those that make up the spinothalamic tract, one of the major routes of nociceptive signaling. + dorsolateral tract of Lissauer morphogenesis + biological_process + GO:0021963 + spinothalamic tract morphogenesis + + + + + Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the spinal cord towards target cells in the thalamus. This axonal process is a member of those that make up the spinothalamic tract, one of the major routes of nociceptive signaling. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the red nucleus of the midbrain towards target cells in the spinal cord. + biological_process + GO:0021964 + rubrospinal tract morphogenesis + + + + + Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the red nucleus of the midbrain towards target cells in the spinal cord. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the spinal cord ventral commissure are generated and organized. + biological_process + GO:0021965 + spinal cord ventral commissure morphogenesis + + + + + The process in which the anatomical structures of the spinal cord ventral commissure are generated and organized. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in spinal cord towards target cells in the thalamus. This axonal process is a member of those that make up the trigeminothalamic tract, one of the major routes of nociceptive and temperature signaling from the face. + biological_process + GO:0021974 + trigeminothalamic tract morphogenesis + + + + + Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in spinal cord towards target cells in the thalamus. This axonal process is a member of those that make up the trigeminothalamic tract, one of the major routes of nociceptive and temperature signaling from the face. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0878937420 + + + + + + + + + + + + + + + + + + + + Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the pons towards target cells in the spinal cord. + biological_process + GO:0021975 + pons reticulospinal tract morphogenesis + + + + + Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the pons towards target cells in the spinal cord. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the medulla towards target cells in the spinal cord. + biological_process + GO:0021976 + medulla reticulospinal tract morphogenesis + + + + + Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the medulla towards target cells in the spinal cord. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the superior colliculus of the midbrain towards target cells in the ventral spinal cord. + biological_process + GO:0021977 + tectospinal tract morphogenesis + + + + + Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the superior colliculus of the midbrain towards target cells in the ventral spinal cord. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the pineal gland over time from its initial formation until its mature state. The pineal gland is an endocrine gland that secretes melatonin and is involved in circadian rhythms. + epiphysis development + biological_process + GO:0021982 + pineal gland development + + + + + The progression of the pineal gland over time from its initial formation until its mature state. The pineal gland is an endocrine gland that secretes melatonin and is involved in circadian rhythms. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + epiphysis development + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the pituitary gland over time from its initial formation until its mature state. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands. + biological_process + hypophysis development + GO:0021983 + pituitary gland development + + + + + The progression of the pituitary gland over time from its initial formation until its mature state. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + hypophysis development + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the adenohypophysis over time from its initial formation until its mature state. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus. + adenophysis development + anterior pituitary development + anterior pituitary gland development + biological_process + GO:0021984 + adenohypophysis development + + + + + The progression of the adenohypophysis over time from its initial formation until its mature state. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the neurohypophysis over time from its initial formation until its mature state. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation. + neurophysis development + posterior pituitary development + posterior pituitary gland development + biological_process + GO:0021985 + neurohypophysis development + + + + + The progression of the neurohypophysis over time from its initial formation until its mature state. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the habenula over time from its initial formation until its mature state. The habenula is the group of nuclei that makes up the stalk of the pineal gland. + biological_process + GO:0021986 + habenula development + + + + + The progression of the habenula over time from its initial formation until its mature state. The habenula is the group of nuclei that makes up the stalk of the pineal gland. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:9780721601465 + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the cerebral cortex over time from its initial formation until its mature state. The cerebral cortex is the outer layered region of the telencephalon. + corticogenesis + biological_process + neocortex development + GO:0021987 + cerebral cortex development + + + + + The progression of the cerebral cortex over time from its initial formation until its mature state. The cerebral cortex is the outer layered region of the telencephalon. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + corticogenesis + GOC:bf + PMID:25904839 + + + + + neocortex development + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the olfactory lobe over time from its initial formation until its mature state. The olfactory lobe is the area of the brain that process the neural inputs for the sense of smell. + biological_process + GO:0021988 + olfactory lobe development + + + + + The progression of the olfactory lobe over time from its initial formation until its mature state. The olfactory lobe is the area of the brain that process the neural inputs for the sense of smell. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the olfactory cortex over time from its initial formation until its mature state. The olfactory cortex is involved in the perception of smell. It receives input from the olfactory bulb and is responsible for the identification of odors. + biological_process + GO:0021989 + olfactory cortex development + + + + + The progression of the olfactory cortex over time from its initial formation until its mature state. The olfactory cortex is involved in the perception of smell. It receives input from the olfactory bulb and is responsible for the identification of odors. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + + The formation of the flat, thickened layer of ectodermal cells known as the neural plate. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system. + biological_process + GO:0021990 + neural plate formation + + + + + The formation of the flat, thickened layer of ectodermal cells known as the neural plate. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0878932437 + ISBN:0878932585 + PMID:15806586 + + + + + + + + + + + + + + + The process of joining together the neural folds at either end of the neural tube. + biological_process + GO:0021995 + neuropore closure + + + + + The process of joining together the neural folds at either end of the neural tube. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anterior-most portion of the neural axis is formed by closure of the anterior neuropore. + biological_process + GO:0021996 + lamina terminalis formation + + + + + The process in which the anterior-most portion of the neural axis is formed by closure of the anterior neuropore. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + The process that regulates the coordinated growth and differentiation that establishes the non-random anterior-posterior spatial arrangement of the neural plate. + biological_process + neural plate anterior/posterior pattern formation + GO:0021999 + neural plate anterior/posterior regionalization + + + + + The process that regulates the coordinated growth and differentiation that establishes the non-random anterior-posterior spatial arrangement of the neural plate. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + neural plate anterior/posterior pattern formation + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The formation of the narrow stripe of cells that lies between the prospective dorsal and ventral thalami. This boundary contains signals that pattern the prethalamic and thalamic territories of the future mid-diencephalon. + zli biosynthesis + zli formation + biological_process + GO:0022006 + zona limitans intrathalamica formation + + + + + The formation of the narrow stripe of cells that lies between the prospective dorsal and ventral thalami. This boundary contains signals that pattern the prethalamic and thalamic territories of the future mid-diencephalon. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + PMID:11425897 + PMID:16452095 + + + + + + + + + + + + + + + Generation of cells within the nervous system. + Wikipedia:Neurogenesis + nervous system cell generation + biological_process + neural cell differentiation + GO:0022008 + neurogenesis + + + + + Generation of cells within the nervous system. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + nervous system cell generation + + + + + + neural cell differentiation + GOC:BHF + GOC:dph + + + + + + + + + + + + + + + + + + + + The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes in the central nervous system. The capillary endothelial cells in the brain are specialized to form the blood-brain barrier. + https://github.com/geneontology/go-ontology/issues/21480 + biological_process + GO:0022009 + central nervous system vasculogenesis + + + + + The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes in the central nervous system. The capillary endothelial cells in the brain are specialized to form the blood-brain barrier. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of oligodendrocytes in the central nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier. + myelination in central nervous system + biological_process + GO:0022010 + central nervous system myelination + + + + + The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of oligodendrocytes in the central nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of Schwann cells in the peripheral nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier. + peripheral nervous system myelination + biological_process + GO:0022011 + myelination in peripheral nervous system + + + + + The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of Schwann cells in the peripheral nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + The multiplication or reproduction of subpallium cells in the forebrain, resulting in the expansion of a cell population. + biological_process + GO:0022012 + subpallium cell proliferation in forebrain + + + + + The multiplication or reproduction of subpallium cells in the forebrain, resulting in the expansion of a cell population. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The migration of cells in the telencephalon from the subventricular zone to the olfactory bulb in which cells move orthogonally to the direction of radial migration and do not use radial glial cell processes as substrates for migration. + rostral migratory stream migration + biological_process + GO:0022028 + tangential migration from the subventricular zone to the olfactory bulb + + + + + The migration of cells in the telencephalon from the subventricular zone to the olfactory bulb in which cells move orthogonally to the direction of radial migration and do not use radial glial cell processes as substrates for migration. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + The orderly movement of a cell from one site to another at least one of which is located in the telencephalon. + biological_process + GO:0022029 + telencephalon cell migration + + + + + The orderly movement of a cell from one site to another at least one of which is located in the telencephalon. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + The orderly movement of glial cells through the telencephalon. + biological_process + GO:0022030 + telencephalon glial cell migration + + + + + The orderly movement of glial cells through the telencephalon. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + The orderly movement of an astrocyte cell through the telencephalon. + biological_process + GO:0022031 + telencephalon astrocyte cell migration + + + + + The orderly movement of an astrocyte cell through the telencephalon. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + The multiplication or reproduction of telencephalon oligodendrocyte cells, resulting in the expansion of a cell population. + biological_process + GO:0022032 + telencephalon oligodendrocyte cell migration + + + + + The multiplication or reproduction of telencephalon oligodendrocyte cells, resulting in the expansion of a cell population. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + The movement of a cell within a rhombomere. This process is known to occur as an early step in the generation of anatomical structure from a rhombomere. + biological_process + GO:0022035 + rhombomere cell migration + + + + + The movement of a cell within a rhombomere. This process is known to occur as an early step in the generation of anatomical structure from a rhombomere. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + PMID:15629700 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the metencephalon over time, from its formation to the mature structure. + biological_process + GO:0022037 + metencephalon development + + + + + The process whose specific outcome is the progression of the metencephalon over time, from its formation to the mature structure. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the corpus callosum over time, from its formation to the mature structure. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provide communication between the right and left cerebral hemispheres. + biological_process + GO:0022038 + corpus callosum development + + + + + The process whose specific outcome is the progression of the corpus callosum over time, from its formation to the mature structure. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provide communication between the right and left cerebral hemispheres. + GOC:cls + GOC:curators + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + The cellular process that ensures successive accurate and complete genome replication and chromosome segregation. + biological_process + GO:0022402 + + cell cycle process + + + + + The cellular process that ensures successive accurate and complete genome replication and chromosome segregation. + GOC:isa_complete + GOC:mtg_cell_cycle + + + + + + + + + + + + + + + A multicellular organismal process involved in the periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin. + biological_process + GO:0022404 + molting cycle process + + + + + A multicellular organismal process involved in the periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin. + GOC:isa_complete + + + + + + + + + + + + + + + A multicellular organismal process involved in the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body. + biological_process + GO:0022405 + hair cycle process + + + + + A multicellular organismal process involved in the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body. + GOC:isa_complete + + + + + + + + + The initial attachment of a membrane or protein to a target membrane. Docking requires only that the proteins come close enough to interact and adhere. + biological_process + GO:0022406 + + membrane docking + + + + + The initial attachment of a membrane or protein to a target membrane. Docking requires only that the proteins come close enough to interact and adhere. + GOC:isa_complete + PMID:27875684 + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of attachment of a cell to another cell. + biological_process + GO:0022407 + regulation of cell-cell adhesion + + + + + Any process that modulates the frequency, rate or extent of attachment of a cell to another cell. + GOC:isa_complete + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the rate or extent of cell adhesion to another cell. + down regulation of cell-cell adhesion + down-regulation of cell-cell adhesion + downregulation of cell-cell adhesion + inhibition of cell-cell adhesion + biological_process + GO:0022408 + negative regulation of cell-cell adhesion + + + + + Any process that stops, prevents or reduces the rate or extent of cell adhesion to another cell. + GOC:isa_complete + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the rate or extent of cell adhesion to another cell. + up regulation of cell-cell adhesion + up-regulation of cell-cell adhesion + upregulation of cell-cell adhesion + activation of cell-cell adhesion + stimulation of cell-cell adhesion + biological_process + GO:0022409 + positive regulation of cell-cell adhesion + + + + + Any process that activates or increases the rate or extent of cell adhesion to another cell. + GOC:isa_complete + + + + + + + + + + + + + + + A behavioral process involved in the cycle from wakefulness through an orderly succession of sleep states and stages that occurs on an approximately 24 hour rhythm. + biological_process + GO:0022410 + circadian sleep/wake cycle process + + + + + A behavioral process involved in the cycle from wakefulness through an orderly succession of sleep states and stages that occurs on an approximately 24 hour rhythm. + GOC:isa_complete + + + + + + + + + + + + + + + + + + + + + A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular organism. + reproductive cellular process in multicellular organism + biological_process + GO:0022412 + cellular process involved in reproduction in multicellular organism + + + + + A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular organism. + GOC:isa_complete + + + + + + + + + + + + + + + + + + + + + + + + + + + A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents. + jl + 2012-09-19T15:56:06Z + GO:0044702 + biological_process + single organism reproductive process + GO:0022414 + + reproductive process + + + + + A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents. + GOC:dph + GOC:isa_complete + + + + + + + + + + + + + + + + + + + + A physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. + biological_process + GO:0022600 + + digestive system process + + + + + A physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. + GOC:isa_complete + GOC:jid + GOC:mtg_cardio + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A process involved in the sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years. + biological_process + estrous cycle process + menstrual cycle process + GO:0022602 + ovulation cycle process + + + + + A process involved in the sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years. + GOC:isa_complete + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of anatomical structure morphogenesis. + regulation of morphogenesis + biological_process + GO:0022603 + regulation of anatomical structure morphogenesis + + + + + Any process that modulates the frequency, rate or extent of anatomical structure morphogenesis. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process in which the shape of a cell is generated and organized. + biological_process + negative regulation of cell shape and cell size + positive regulation of cell shape and cell size + regulation of cell shape and cell size + GO:0022604 + regulation of cell morphogenesis + + + + + Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process in which the shape of a cell is generated and organized. + GOC:isa_complete + + + + + negative regulation of cell shape and cell size + GOC:dph + GOC:tb + + + + + positive regulation of cell shape and cell size + GOC:dph + GOC:tb + + + + + regulation of cell shape and cell size + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + A reproductive process that is a step in the formation and maturation of an ovum or female gamete from a primordial female germ cell. + mammalian oogenesis process + biological_process + GO:0022605 + mammalian oogenesis stage + + + + + A reproductive process that is a step in the formation and maturation of an ovum or female gamete from a primordial female germ cell. + GOC:isa_complete + GOC:mtg_sensu + + + + + + + + + + + + + + + + + + + + + + + + + + The aggregation, arrangement and bonding together of a cellular component. + GO:0071844 + cell structure assembly + cellular component assembly at cellular level + biological_process + GO:0022607 + + + cellular component assembly + + + + + The aggregation, arrangement and bonding together of a cellular component. + GOC:isa_complete + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of a gland are generated and organized. + biological_process + GO:0022612 + gland morphogenesis + + + + + The process in which the anatomical structures of a gland are generated and organized. + GOC:isa_complete + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a signal is released and/or conveyed from one location to another. + 2010-02-16T09:30:50Z + biological_process + regulation of gene expression as a consequence of signal transmission + GO:0023019 + signal transduction involved in regulation of gene expression + + + + + Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a signal is released and/or conveyed from one location to another. + GOC:mtg_signal + + + + + regulation of gene expression as a consequence of signal transmission + GOC:bf + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of a signaling process. + 2010-02-16T09:30:50Z + biological_process + regulation of signaling process + regulation of signalling process + GO:0023051 + regulation of signaling + + + + + Any process that modulates the frequency, rate or extent of a signaling process. + GOC:mtg_signal + + + + + regulation of signaling process + GOC:bf + + + + + regulation of signalling process + GOC:mah + + + + + + + + + + The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered. + jl + 2010-02-16T09:30:50Z + GO:0023046 + GO:0044700 + biological signaling + signaling process + signalling + biological_process + signalling process + single organism signaling + GO:0023052 + + + + + + + + Note that a signal is any variable property or parameter that serves to convey information, and may be a physical entity such as a gene product or small molecule, a photon, or a change in state such as movement or voltage change. + signaling + + + + + The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered. + GOC:mtg_signal + GOC:mtg_signaling_feb11 + GOC:signaling + + + + + signalling process + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + + Any process that activates, maintains or increases the frequency, rate or extent of a signaling process. + 2010-02-16T09:30:50Z + positive regulation of signalling process + biological_process + positive regulation of signaling process + GO:0023056 + positive regulation of signaling + + + + + Any process that activates, maintains or increases the frequency, rate or extent of a signaling process. + GOC:mtg_signal + + + + + positive regulation of signalling process + GOC:mah + + + + + positive regulation of signaling process + GOC:bf + + + + + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of a signaling process. + 2010-02-16T09:30:50Z + biological_process + negative regulation of signaling process + negative regulation of signalling process + GO:0023057 + negative regulation of signaling + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of a signaling process. + GOC:mtg_signal + + + + + negative regulation of signaling process + GOC:bf + + + + + negative regulation of signalling process + GOC:mah + + + + + + + + + + + + + + + + + + + + The process in which a signal is secreted or discharged into the extracellular medium from a cellular source. + 2010-02-16T09:30:50Z + signal secretion + biological_process + GO:0023061 + signal release + + + + + The process in which a signal is secreted or discharged into the extracellular medium from a cellular source. + GOC:mtg_signal + + + + + signal secretion + GOC:bf + + + + + + + + + + + + + + + + + + + The directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + https://github.com/geneontology/go-ontology/issues/23033 + mah + 2009-07-31T01:07:46Z + GO:0070838 + GO:0070839 + divalent metal ion export + divalent metal ion transport + heavy metal ion transport + metal ion export + biological_process + GO:0030001 + metal ion transport + + + + + The directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:ai + + + + + + + + + + + + + + + + + + + Any process involved in the maintenance of an internal steady state of cations at the level of a cell. + biological_process + GO:0030003 + cellular cation homeostasis + + + + + Any process involved in the maintenance of an internal steady state of cations at the level of a cell. + GOC:ceb + GOC:mah + + + + + + + + + + + + + + + + + + + Any process involved in the maintenance of an internal steady state of monovalent inorganic cations at the level of a cell. + biological_process + GO:0030004 + cellular monovalent inorganic cation homeostasis + + + + + Any process involved in the maintenance of an internal steady state of monovalent inorganic cations at the level of a cell. + GOC:ai + GOC:mah + + + + + + + + + The specification and formation of anisotropic intracellular organization or cell growth patterns. + GO:0000283 + GO:0030468 + cell polarization + bud site selection/establishment of cell polarity + biological_process + GO:0030010 + establishment of cell polarity + + + + + The specification and formation of anisotropic intracellular organization or cell growth patterns. + GOC:mah + + + + + + + + + + + + + + + + + + + + The contractile element of skeletal and cardiac muscle; a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism. + Wikipedia:Myofibril + cellular_component + GO:0030016 + myofibril + + + + + The contractile element of skeletal and cardiac muscle; a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism. + ISBN:0815316194 + + + + + + + + + + + + + + + + + + + + Any cellular process that depends upon or alters the actin cytoskeleton, that part of the cytoskeleton comprising actin filaments and their associated proteins. + biological_process + microfilament-based process + GO:0030029 + actin filament-based process + + + + + Any cellular process that depends upon or alters the actin cytoskeleton, that part of the cytoskeleton comprising actin filaments and their associated proteins. + GOC:mah + + + + + + + + + + + + + + + + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon. + cell projection organisation + biological_process + cell projection organization and biogenesis + cell surface structure organization and biogenesis + GO:0030030 + + cell projection organization + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon. + GOC:jl + GOC:mah + http://www.cogsci.princeton.edu/~wn/ + + + + + cell projection organization and biogenesis + GOC:mah + + + + + cell surface structure organization and biogenesis + GOC:mah + + + + + + + + + + + + + + + + + + + + Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon. + formation of a cell surface projection + biological_process + cell projection biogenesis + GO:0030031 + cell projection assembly + + + + + Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon. + GOC:jl + GOC:mah + http://www.cogsci.princeton.edu/~wn/ + + + + + cell projection biogenesis + GOC:mah + + + + + + + + + + + + + + + + + + + + Formation of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell. + biological_process + microvillus biogenesis + GO:0030033 + microvillus assembly + + + + + Formation of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell. + GOC:mah + ISBN:0815316194 + + + + + microvillus biogenesis + GOC:mah + + + + + + + + + + + + + + + + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins. + https://github.com/geneontology/go-ontology/issues/23114 + actin cytoskeleton organisation + biological_process + actin cytoskeleton organization and biogenesis + actin modulating activity + GO:0030036 + + actin cytoskeleton organization + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins. + GOC:dph + GOC:jl + GOC:mah + + + + + actin cytoskeleton organization and biogenesis + GOC:mah + + + + + + + + + + + + + + + Movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins. + https://github.com/geneontology/go-ontology/issues/19809 + biological_process + GO:0030048 + actin filament-based movement + + + + + Movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins. + GOC:BHF + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + Movement of a vesicle along an actin filament, mediated by motor proteins. + biological_process + GO:0030050 + vesicle transport along actin filament + + + + + Movement of a vesicle along an actin filament, mediated by motor proteins. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A cellular component that forms a specialized region of connection between two or more cells, or between a cell and the extracellular matrix, or between two membrane-bound components of a cell, such as flagella. + + Wikipedia:Cell_junction + cellular_component + GO:0030054 + + + + cell junction + + + + + A cellular component that forms a specialized region of connection between two or more cells, or between a cell and the extracellular matrix, or between two membrane-bound components of a cell, such as flagella. + GOC:aruk + GOC:bc + GOC:mah + ISBN:0198506732 + PMID:26820516 + PMID:28096264 + http://www.vivo.colostate.edu/hbooks/cmb/cells/pmemb/junctions_a.html + + + + + + + + + + + + + + + + + + + + + The regulated release of a peptide hormone from a cell. + biological_process + GO:0030072 + peptide hormone secretion + + + + + The regulated release of a peptide hormone from a cell. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The regulated release of proinsulin from secretory granules accompanied by cleavage of proinsulin to form mature insulin. In vertebrates, insulin is secreted from B granules in the B cells of the vertebrate pancreas and from insulin-producing cells in insects. + https://github.com/geneontology/go-ontology/issues/11255#issuecomment-426191045 + biological_process + GO:0030073 + insulin secretion + + + + + The regulated release of proinsulin from secretory granules accompanied by cleavage of proinsulin to form mature insulin. In vertebrates, insulin is secreted from B granules in the B cells of the vertebrate pancreas and from insulin-producing cells in insects. + GOC:mah + ISBN:0198506732 + + + + + + + + + The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates. + Wikipedia:Haematopoiesis + blood cell biosynthesis + blood cell formation + haemopoiesis + hematopoiesis + biological_process + GO:0030097 + hemopoiesis + + + + + The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates. + GOC:dgh + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized precursor cell acquires specialized features of a lymphocyte. A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin. + GO:0046650 + lymphocyte cell differentiation + lymphocytic blood cell differentiation + biological_process + lymphocyte development + GO:0030098 + Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. + lymphocyte differentiation + + + + + The process in which a relatively unspecialized precursor cell acquires specialized features of a lymphocyte. A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin. + CL:0000542 + GOC:go_curators + + + + + lymphocyte development + GOC:add + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages. + biological_process + GO:0030099 + myeloid cell differentiation + + + + + The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages. + GOC:add + ISBN:0781735149 + + + + + + + + + + + + + + + + + + + + The regulated release of vasopressin from secretory granules into the blood. + biological_process + GO:0030103 + vasopressin secretion + + + + + The regulated release of vasopressin from secretory granules into the blood. + GOC:mah + + + + + + + + + + + + + + + + + + + + Any process involved in the maintenance of an internal steady state of water within an organism or cell. + GO:0018987 + Wikipedia:Osmoregulation + regulation of osmotic pressure + biological_process + osmoregulation + GO:0030104 + water homeostasis + + + + + Any process involved in the maintenance of an internal steady state of water within an organism or cell. + GOC:dph + GOC:mah + GOC:tb + + + + + + + + + + + + + + + Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, from the Golgi to the ER (retrograde transport) or to destinations within or outside the cell. + NIF_Subcellular:sao885490876 + constitutive secretory pathway transport vesicle + Golgi to vacuole transport vesicle + Golgi-vacuole transport vesicle + cellular_component + secretory vesicle + GO:0030133 + Note that the term 'secretory vesicle' is sometimes used in this sense, but can also mean 'secretory granule ; GO:0030141'. + transport vesicle + + + + + Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, from the Golgi to the ER (retrograde transport) or to destinations within or outside the cell. + GOC:mah + PMID:22160157 + + + + + + + + + + + + + + + + + + + + The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. + Wikipedia:Cellular_differentiation + biological_process + GO:0030154 + + + + + + + cell differentiation + + + + + The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix. + biological_process + cell adhesion receptor regulator activity + GO:0030155 + regulation of cell adhesion + + + + + Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix. + GOC:mah + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. + https://github.com/geneontology/go-ontology/issues/23112 + GO:0044254 + GO:0044257 + Wikipedia:Protein_catabolism + cellular protein breakdown + cellular protein catabolic process + cellular protein catabolism + cellular protein degradation + protein breakdown + protein catabolism + protein degradation + multicellular organismal protein catabolic process + biological_process + pheromone catabolic process + pheromone catabolism + GO:0030163 + + + + + + This term refers to the breakdown of mature proteins. For cleavage events involved in generating a mature protein from a precursor, consider instead the term 'protein maturation ; GO:0051604' and its children. + protein catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. + GOC:mah + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans. + proteoglycan anabolism + proteoglycan biosynthesis + proteoglycan formation + proteoglycan synthesis + biological_process + GO:0030166 + proteoglycan biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans. + GOC:mah + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans. + proteoglycan breakdown + proteoglycan catabolism + proteoglycan degradation + biological_process + GO:0030167 + proteoglycan catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans. + GOC:mah + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + + + + + + + A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug. + blood coagulation, platelet activation + biological_process + GO:0030168 + platelet activation + + + + + A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug. + http://www.graylab.ac.uk/omd/ + + + + + blood coagulation, platelet activation + GOC:add + GOC:pde + + + + + + + + + + + + + + + + + + + The component of the Golgi membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. + integral to Golgi membrane + cellular_component + Golgi integral membrane protein + GO:0030173 + integral component of Golgi membrane + + + + + The component of the Golgi membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of a neuron. + biological_process + GO:0030182 + neuron differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized features of a neuron. + GOC:mah + + + + + + + + + + + + + + + + + + + + + The process in which a precursor cell type acquires the specialized features of a B cell. A B cell is a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity. + GO:0042115 + B lymphocyte differentiation + B-cell differentiation + B-lymphocyte differentiation + biological_process + B cell development + GO:0030183 + Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. + B cell differentiation + + + + + The process in which a precursor cell type acquires the specialized features of a B cell. A B cell is a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity. + GOC:mah + GO_REF:0000022 + + + + + B cell development + GOC:add + + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways involving melatonin (N-acetyl-5-methoxytryptamine). + melatonin metabolism + biological_process + GO:0030186 + melatonin metabolic process + + + + + The chemical reactions and pathways involving melatonin (N-acetyl-5-methoxytryptamine). + GOC:mah + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of melatonin (N-acetyl-5-methoxytryptamine). + melatonin anabolism + melatonin biosynthesis + melatonin formation + melatonin synthesis + biological_process + GO:0030187 + melatonin biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of melatonin (N-acetyl-5-methoxytryptamine). + GOC:mah + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of blood coagulation. + biological_process + GO:0030193 + regulation of blood coagulation + + + + + Any process that modulates the frequency, rate or extent of blood coagulation. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of blood coagulation. + up regulation of blood coagulation + up-regulation of blood coagulation + upregulation of blood coagulation + activation of blood coagulation + stimulation of blood coagulation + biological_process + GO:0030194 + positive regulation of blood coagulation + + + + + Any process that activates or increases the frequency, rate or extent of blood coagulation. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of blood coagulation. + down regulation of blood coagulation + down-regulation of blood coagulation + downregulation of blood coagulation + inhibition of blood coagulation + biological_process + GO:0030195 + negative regulation of blood coagulation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of blood coagulation. + GOC:mah + + + + + + + + + + + + + + + + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix. + extracellular matrix organisation + biological_process + extracellular matrix organization and biogenesis + GO:0030198 + + + + extracellular matrix organization + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix. + GOC:mah + + + + + extracellular matrix organization and biogenesis + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Any process that determines the size and arrangement of collagen fibrils within an extracellular matrix. + + collagen fibril organisation + fibrillar collagen organization + biological_process + GO:0030199 + collagen fibril organization + + + + + Any process that determines the size and arrangement of collagen fibrils within an extracellular matrix. + GOC:mah + ISBN:0815316194 + + + + + fibrillar collagen organization + GOC:mah + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways involving glycosaminoglycans, any of a group of polysaccharides that contain amino sugars. + glycosaminoglycan metabolism + biological_process + GO:0030203 + glycosaminoglycan metabolic process + + + + + The chemical reactions and pathways involving glycosaminoglycans, any of a group of polysaccharides that contain amino sugars. + ISBN:0192800981 + + + + + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways involving chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate. They usually occur linked to a protein to form proteoglycans. Two subgroups exist, one in which the sulfate is on the 4-position (chondroitin sulfate A) and the second in which it is in the 6-position (chondroitin sulfate C). They often are polydisperse and often differ in the degree of sulfation from tissue to tissue. The chains of repeating disaccharide are covalently linked to the side chains of serine residues in the polypeptide backbone of a protein by a glycosidic attachment through the trisaccharide unit galactosyl-galactosyl-xylosyl. Chondroitin sulfate B is more usually known as dermatan sulfate. + chondroitin sulfate metabolism + chondroitin sulphate metabolic process + chondroitin sulphate metabolism + biological_process + GO:0030204 + chondroitin sulfate metabolic process + + + + + The chemical reactions and pathways involving chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate. They usually occur linked to a protein to form proteoglycans. Two subgroups exist, one in which the sulfate is on the 4-position (chondroitin sulfate A) and the second in which it is in the 6-position (chondroitin sulfate C). They often are polydisperse and often differ in the degree of sulfation from tissue to tissue. The chains of repeating disaccharide are covalently linked to the side chains of serine residues in the polypeptide backbone of a protein by a glycosidic attachment through the trisaccharide unit galactosyl-galactosyl-xylosyl. Chondroitin sulfate B is more usually known as dermatan sulfate. + GOC:mah + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate. + chondroitin sulfate anabolism + chondroitin sulfate biosynthesis + chondroitin sulfate formation + chondroitin sulfate synthesis + chondroitin sulphate biosynthesis + chondroitin sulphate biosynthetic process + biological_process + GO:0030206 + chondroitin sulfate biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate. + GOC:mah + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate. + chondroitin sulfate breakdown + chondroitin sulfate catabolism + chondroitin sulfate degradation + chondroitin sulphate catabolic process + chondroitin sulphate catabolism + biological_process + GO:0030207 + chondroitin sulfate catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate. + GOC:mah + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways involving hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine. + hyaluronan metabolism + biological_process + GO:0030212 + hyaluronan metabolic process + + + + + The chemical reactions and pathways involving hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine. + GOC:mah + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine. + hyaluronan anabolism + hyaluronan biosynthesis + hyaluronan formation + hyaluronan synthesis + biological_process + GO:0030213 + hyaluronan biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine. + GOC:mah + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine. + hyaluronan breakdown + hyaluronan catabolism + hyaluronan degradation + biological_process + GO:0030214 + hyaluronan catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine. + GOC:mah + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of a keratinocyte. + keratinocyte cell differentiation + biological_process + GO:0030216 + keratinocyte differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized features of a keratinocyte. + GOC:dph + GOC:mah + GOC:sdb_2009 + GOC:tb + + + + + + + + + + + + + + + + + + + + + The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex. + GO:0042112 + GO:0046652 + T lymphocyte differentiation + T-cell differentiation + T-lymphocyte differentiation + biological_process + T cell development + GO:0030217 + Note that the term 'thymocyte differentiation' was merged into this term because thymocytes are T cells, and thus the term was essentially redundant. Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. + T cell differentiation + + + + + The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex. + GOC:jid + GOC:mah + GO_REF:0000022 + + + + + T cell development + GOC:add + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a myeloid precursor cell acquires specializes features of an erythrocyte. + Wikipedia:Erythropoiesis + RBC differentiation + erythrocyte cell differentiation + erythropoiesis + red blood cell differentiation + biological_process + GO:0030218 + erythrocyte differentiation + + + + + The process in which a myeloid precursor cell acquires specializes features of an erythrocyte. + GOC:mah + + + + + RBC differentiation + CL:0000232 + + + + + erythropoiesis + GOC:add + GOC:dph + + + + + red blood cell differentiation + CL:0000232 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which platelets bud from long processes extended by megakaryocytes. + platelet extrusion + biological_process + GO:0030220 + platelet formation + + + + + The process in which platelets bud from long processes extended by megakaryocytes. + GOC:mah + ISBN:0815316194 + + + + + platelet extrusion + GOC:curators + + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized monocyte acquires the specialized features of a macrophage. + macrophage cell differentiation + biological_process + GO:0030225 + macrophage differentiation + + + + + The process in which a relatively unspecialized monocyte acquires the specialized features of a macrophage. + GOC:add + ISBN:0781735149 + + + + + + + + + + + + + + + + + + + + + + + + + Binds to and modulates the activity of an enzyme. + GO:0010576 + catalytic regulator activity + enzyme modulator + metalloenzyme regulator activity + molecular_function + GO:0030234 + + + + + + + + + This term should only be used in cases when the regulator directly interacts with the enzyme. + enzyme regulator activity + + + + + Binds to and modulates the activity of an enzyme. + GOC:dph + GOC:mah + GOC:tb + + + + + catalytic regulator activity + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + Formation of myofibrils, the repeating units of striated muscle. + biological_process + GO:0030239 + myofibril assembly + + + + + Formation of myofibrils, the repeating units of striated muscle. + GOC:mah + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways involving cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation. + GO:0016177 + cellulose metabolism + biological_process + GO:0030243 + cellulose metabolic process + + + + + The chemical reactions and pathways involving cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation. + GOC:mah + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation. + GO:0016178 + MetaCyc:PWY-1001 + cellulose anabolism + cellulose biosynthesis + cellulose formation + cellulose synthesis + biological_process + GO:0030244 + cellulose biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation. + GOC:mah + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation. + GO:0016179 + cellulose breakdown + cellulose catabolism + cellulose degradation + biological_process + GO:0030245 + cellulose catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation. + GOC:mah + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + Binding to a carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates. + GO:0005529 + sugar binding + molecular_function + selectin + GO:0030246 + + + + + + + + carbohydrate binding + + + + + Binding to a carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates. + GOC:mah + + + + + + + + + + + + + + + + + + + Binding to a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. + GO:0002506 + polysaccharide assembly with MHC class II protein complex + molecular_function + GO:0030247 + polysaccharide binding + + + + + Binding to a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically. + GOC:mah + + + + + + + + + + + + + + + + + + + Binding to cellulose. + molecular_function + GO:0030248 + cellulose binding + + + + + Binding to cellulose. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance. + regulation of bone biosynthesis + regulation of bone formation + biological_process + GO:0030278 + regulation of ossification + + + + + Any process that modulates the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance. + down regulation of ossification + down-regulation of ossification + downregulation of ossification + negative regulation of bone biosynthesis + negative regulation of bone formation + inhibition of ossification + biological_process + GO:0030279 + negative regulation of ossification + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + + + + + The deposition of hydroxyapatite, a form of calcium phosphate with the formula Ca10(PO4)6(OH)2, in bone tissue. + bone calcification + biological_process + GO:0030282 + bone mineralization + + + + + The deposition of hydroxyapatite, a form of calcium phosphate with the formula Ca10(PO4)6(OH)2, in bone tissue. + GOC:mah + PMID:22936354 + + + + + + + + + + + + + + + + + + + + + + + + + Stops, prevents or reduces the activity of a protein tyrosine kinase. + molecular_function + GO:0030292 + protein tyrosine kinase inhibitor activity + + + + + Stops, prevents or reduces the activity of a protein tyrosine kinase. + GOC:mah + + + + + + + + + + + + + + + + + + + Binds to and stops, prevents or reduces the activity of a transmembrane receptor protein tyrosine kinase. + molecular_function + GO:0030293 + transmembrane receptor protein tyrosine kinase inhibitor activity + + + + + Binds to and stops, prevents or reduces the activity of a transmembrane receptor protein tyrosine kinase. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + Binds to and increases the activity of a protein kinase, an enzyme which phosphorylates a protein. + molecular_function + GO:0030295 + protein kinase activator activity + + + + + Binds to and increases the activity of a protein kinase, an enzyme which phosphorylates a protein. + GOC:ai + + + + + + + + + + + + + + + + + + + + + + + + + Increases the activity of a protein tyrosine kinase, an enzyme which phosphorylates a tyrosyl phenolic group on a protein. + molecular_function + GO:0030296 + protein tyrosine kinase activator activity + + + + + Increases the activity of a protein tyrosine kinase, an enzyme which phosphorylates a tyrosyl phenolic group on a protein. + GOC:ai + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + + + + + + + Binds to and increases the activity of a transmembrane receptor protein tyrosine kinase. + molecular_function + GO:0030297 + transmembrane receptor protein tyrosine kinase activator activity + + + + + Binds to and increases the activity of a transmembrane receptor protein tyrosine kinase. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate, extent or direction of cell growth. + up regulation of cell growth + up-regulation of cell growth + upregulation of cell growth + activation of cell growth + stimulation of cell growth + biological_process + GO:0030307 + positive regulation of cell growth + + + + + Any process that activates or increases the frequency, rate, extent or direction of cell growth. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth. + down regulation of cell growth + down-regulation of cell growth + downregulation of cell growth + inhibition of cell growth + biological_process + GO:0030308 + negative regulation of cell growth + + + + + Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + A structure that lies outside the plasma membrane and surrounds the entire cell or cells. This does not include the periplasmic space. + cellular_component + GO:0030312 + + + + + + The outer membrane (of gram negative bacteria) or cell wall (of yeast or Gram positive bacteria) are defined as parts of this structure, see 'external encapsulating structure part'. + external encapsulating structure + + + + + A structure that lies outside the plasma membrane and surrounds the entire cell or cells. This does not include the periplasmic space. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + The directed, self-propelled movement of a cilium (aka flagellum) that contributes to the movement of a flagellated sperm. + GO:0097724 + GO:1905419 + sperm motility + sperm movement + Wikipedia:Sperm_motility + flagellated sperm movement + sperm flagellum movement + sperm flagellum movement involved in flagellated sperm motility + sperm flagellum movement involved in flagellated sperm movement + biological_process + GO:0030317 + flagellated sperm motility + + + + + The directed, self-propelled movement of a cilium (aka flagellum) that contributes to the movement of a flagellated sperm. + GOC:TermGenie + GOC:cilia + GOC:krc + GO_REF:0000060 + PMID:26680031 + + + + + sperm flagellum movement + GOC:cilia + GOC:krc + + + + + sperm flagellum movement involved in flagellated sperm movement + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of a melanocyte. + melanocyte cell differentiation + melanophore differentiation + biological_process + GO:0030318 + melanocyte differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized features of a melanocyte. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the respiratory tube over time, from its formation to the mature structure. The respiratory tube is assumed to mean any tube in the respiratory tract. + biological_process + GO:0030323 + respiratory tube development + + + + + The process whose specific outcome is the progression of the respiratory tube over time, from its formation to the mature structure. The respiratory tube is assumed to mean any tube in the respiratory tract. + GOC:jid + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax. + biological_process + GO:0030324 + lung development + + + + + The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax. + GOC:jid + UBERON:0002048 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the adrenal gland over time, from its formation to the mature structure. This gland can either be a discrete structure located bilaterally above each kidney, or a cluster of cells in the head kidney that perform the functions of the adrenal gland. In either case, this organ consists of two cells types, aminergic chromaffin cells and steroidogenic cortical cells. + biological_process + interrenal gland + GO:0030325 + adrenal gland development + + + + + The process whose specific outcome is the progression of the adrenal gland over time, from its formation to the mature structure. This gland can either be a discrete structure located bilaterally above each kidney, or a cluster of cells in the head kidney that perform the functions of the adrenal gland. In either case, this organ consists of two cells types, aminergic chromaffin cells and steroidogenic cortical cells. + GOC:dgh + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of cell migration. + biological_process + GO:0030334 + regulation of cell migration + + + + + Any process that modulates the frequency, rate or extent of cell migration. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of cell migration. + up regulation of cell migration + up-regulation of cell migration + upregulation of cell migration + activation of cell migration + stimulation of cell migration + biological_process + GO:0030335 + positive regulation of cell migration + + + + + Any process that activates or increases the frequency, rate or extent of cell migration. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration. + down regulation of cell migration + down-regulation of cell migration + downregulation of cell migration + inhibition of cell migration + biological_process + GO:0030336 + negative regulation of cell migration + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration. + GOC:go_curators + + + + + + + + + + + + + + + + The expulsion of feces from the rectum. + Wikipedia:Defecation + biological_process + GO:0030421 + defecation + + + + + The expulsion of feces from the rectum. + GOC:mah + + + + + + + + + The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter. + NIF_Subcellular:sao1770195789 + Wikipedia:Axon + cellular_component + GO:0030424 + axon + + + + + The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter. + GOC:nln + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + + A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body. + NIF_Subcellular:sao1211023249 + Wikipedia:Dendrite + cellular_component + GO:0030425 + dendrite + + + + + A neuron projection that has a short, tapering, morphology. Dendrites receive and integrate signals from other neurons or from sensory stimuli, and conduct nerve impulses towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body. + GOC:aruk + GOC:bc + GOC:dos + GOC:mah + GOC:nln + ISBN:0198506732 + + + + + + + + + Any process in which an organism enters and maintains a periodic, readily reversible state of reduced awareness and metabolic activity. Usually accompanied by physical relaxation, the onset of sleep in humans and other mammals is marked by a change in the electrical activity of the brain. + Wikipedia:Sleep + biological_process + diapause + dormancy + lethargus + GO:0030431 + + sleep + + + + + Any process in which an organism enters and maintains a periodic, readily reversible state of reduced awareness and metabolic activity. Usually accompanied by physical relaxation, the onset of sleep in humans and other mammals is marked by a change in the electrical activity of the brain. + ISBN:0192800981 + + + + + + + + + A wavelike sequence of involuntary muscular contraction and relaxation that passes along a tubelike structure, such as the intestine, impelling the contents onwards. + Wikipedia:Peristalsis + biological_process + GO:0030432 + peristalsis + + + + + A wavelike sequence of involuntary muscular contraction and relaxation that passes along a tubelike structure, such as the intestine, impelling the contents onwards. + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + The directed movement of the nucleus along microtubules within the cell, mediated by motor proteins. + GO:0000065 + nuclear movement, microtubule-mediated + nucleus migration + microtubule cytoskeleton-dependent nuclear positioning + microtubule cytoskeleton-dependent nucleus positioning + microtubule-dependent nuclear positioning + microtubule-dependent nucleus positioning + microtubule-mediated nuclear migration + nuclear migration, microtubule-mediated + transport of nucleus by microtubules + transport of nucleus, microtubule-mediated + biological_process + GO:0030473 + nuclear migration along microtubule + + + + + The directed movement of the nucleus along microtubules within the cell, mediated by motor proteins. + GOC:mah + GOC:sgd_curators + + + + + + + + + + + + + + + + + + + The contractile fiber of smooth muscle cells. + cellular_component + GO:0030485 + smooth muscle contractile fiber + + + + + The contractile fiber of smooth muscle cells. + GOC:mah + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of bone mineralization. + biological_process + GO:0030500 + regulation of bone mineralization + + + + + Any process that modulates the frequency, rate or extent of bone mineralization. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of bone mineralization. + up regulation of bone mineralization + up-regulation of bone mineralization + upregulation of bone mineralization + activation of bone mineralization + stimulation of bone mineralization + biological_process + GO:0030501 + positive regulation of bone mineralization + + + + + Any process that activates or increases the frequency, rate or extent of bone mineralization. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of bone mineralization. + down regulation of bone mineralization + down-regulation of bone mineralization + downregulation of bone mineralization + inhibition of bone mineralization + biological_process + GO:0030502 + negative regulation of bone mineralization + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of bone mineralization. + GOC:go_curators + + + + + + + + + + The series of molecular signals initiated by a steroid binding to an intracellular steroid hormone receptor. + steroid hormone receptor signaling pathway + steroid hormone receptor signalling pathway + biological_process + GO:0030518 + intracellular steroid hormone receptor signaling pathway + + + + + The series of molecular signals initiated by a steroid binding to an intracellular steroid hormone receptor. + GOC:mah + GOC:signaling + + + + + steroid hormone receptor signaling pathway + GOC:bf + + + + + steroid hormone receptor signalling pathway + GOC:bf + + + + + + + + + The series of molecular signals initiated by a ligand binding to a receptor located within a cell. + intracellular receptor mediated signaling pathway + intracellular receptor-mediated signaling pathway + intracellular receptor-mediated signalling pathway + biological_process + GO:0030522 + intracellular receptor signaling pathway + + + + + The series of molecular signals initiated by a ligand binding to a receptor located within a cell. + GOC:bf + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the male genitalia over time, from its formation to the mature structure. + male genital development + biological_process + GO:0030539 + male genitalia development + + + + + The process whose specific outcome is the progression of the male genitalia over time, from its formation to the mature structure. + GOC:ems + ISBN:0140512888 + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the female genitalia over time, from formation to the mature structure. + female genital development + biological_process + GO:0030540 + female genitalia development + + + + + The process whose specific outcome is the progression of the female genitalia over time, from formation to the mature structure. + GOC:mah + + + + + + + + + + + + + + + + + + + Binds to and modulates the activity of a receptor. + receptor regulator activity + molecular_function + GO:0030545 + signaling receptor regulator activity + + + + + Binds to and modulates the activity of a receptor. + GOC:ceb + + + + + + + + + + + + + + + + + + + The function of interacting (directly or indirectly) with receptors such that the proportion of receptors in the active form is increased. + receptor activator activity + signalling receptor activator activity + molecular_function + GO:0030546 + signaling receptor activator activity + + + + + The function of interacting (directly or indirectly) with receptors such that the proportion of receptors in the active form is increased. + GOC:ceb + + + + + + + + + + + + + + + + + + + + + + + + + Binds to and modulates the activity of a signaling receptor. + receptor inhibitor activity + molecular_function + GO:0030547 + signaling receptor inhibitor activity + + + + + Binds to and modulates the activity of a signaling receptor. + GOC:ceb + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of bile acids, any of a group of steroid carboxylic acids occurring in bile. + GO:0019613 + MetaCyc:7ALPHADEHYDROX-PWY + bile acid breakdown + bile acid catabolism + bile acid degradation + bile acid 7alpha-dehydroxylation pathway + cholate catabolic process + biological_process + GO:0030573 + bile acid catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of bile acids, any of a group of steroid carboxylic acids occurring in bile. + GOC:go_curators + + + + + + + + + + + + + + + + + + + The proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix, usually carried out by proteases secreted by nearby cells. + collagen breakdown + collagen catabolism + collagen degradation + biological_process + GO:0030574 + collagen catabolic process + + + + + The proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix, usually carried out by proteases secreted by nearby cells. + GOC:mah + ISBN:0815316194 + + + + + + + + + + + + + + + Combining with a neurotransmitter and transmitting the signal to initiate a change in cell activity. + molecular_function + GO:0030594 + A strict definition of neurotransmitter receptor activity would limit its use to receptor activity at the postsynaptic membrane as part of synaptic transmission, but we recognize that usage is often much broader than this. For the strict use case, please see 'postsynaptic neurotransmitter receptor activity' + neurotransmitter receptor activity + + + + + Combining with a neurotransmitter and transmitting the signal to initiate a change in cell activity. + GOC:jl + GOC:signaling + + + + + + + + + + + + + + + + + + + + + + + + + + The lipid bilayer surrounding a transport vesicle. + secretory vesicle membrane + constitutive secretory pathway transport vesicle membrane + cellular_component + GO:0030658 + transport vesicle membrane + + + + + The lipid bilayer surrounding a transport vesicle. + GOC:mah + + + + + + + + + + + + + + + + + + + + The lipid bilayer surrounding a cytoplasmic vesicle. + cellular_component + GO:0030659 + cytoplasmic vesicle membrane + + + + + The lipid bilayer surrounding a cytoplasmic vesicle. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + The lipid bilayer surrounding a vesicle associated with the Golgi apparatus. + cellular_component + Golgi vesicle membrane + GO:0030660 + Golgi-associated vesicle membrane + + + + + The lipid bilayer surrounding a vesicle associated with the Golgi apparatus. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Construction of the eggshell, a product of the somatic follicle cell epithelium and a structure that supports the egg in a hostile environment, minimizing water loss whilst allowing gas exchanges essential for embryonic respiration. + biological_process + GO:0030703 + eggshell formation + + + + + Construction of the eggshell, a product of the somatic follicle cell epithelium and a structure that supports the egg in a hostile environment, minimizing water loss whilst allowing gas exchanges essential for embryonic respiration. + GOC:mtg_sensu + ISBN:0879694238 + PMID:10822261 + + + + + + + + + + + + + + + + + + + + + Construction of the vitelline membrane portion of the egg shell, a rigid structure required to maintain the shape of the egg. + biological_process + GO:0030704 + vitelline membrane formation + + + + + Construction of the vitelline membrane portion of the egg shell, a rigid structure required to maintain the shape of the egg. + ISBN:0879694238 + + + + + + + + + + + + + + + + + + + The directed movement of substances along cytoskeletal fibers such as microfilaments or microtubules within a cell. + biological_process + GO:0030705 + + + cytoskeleton-dependent intracellular transport + + + + + The directed movement of substances along cytoskeletal fibers such as microfilaments or microtubules within a cell. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process that occurs during oogenesis involving the ovarian follicle cells, somatic cells which surround the germ cells of an ovary. An example of this is found in Drosophila melanogaster. + biological_process + GO:0030707 + ovarian follicle cell development + + + + + The process that occurs during oogenesis involving the ovarian follicle cells, somatic cells which surround the germ cells of an ovary. An example of this is found in Drosophila melanogaster. + GOC:mtg_sensu + PMID:10822261 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Directed movement of the oocyte, following its specification, from its original central position in the cyst to a posterior position relative to the nurse cells of the egg chamber, and its maintenance in this posterior location. This is the first sign of anterior-posterior asymmetry in the developing egg chamber. + establishment and maintenance of oocyte localization in egg chamber + establishment and maintenance of oocyte position during oogenesis + oocyte localisation involved in germarium-derived egg chamber formation + oogenesis, establishment and maintenance of oocyte localization + oogenesis, oocyte localization + oocyte positioning during oogenesis + biological_process + oocyte localization during germarium-derived egg chamber formation + oocyte localization during oogenesis + GO:0030720 + oocyte localization involved in germarium-derived egg chamber formation + + + + + Directed movement of the oocyte, following its specification, from its original central position in the cyst to a posterior position relative to the nurse cells of the egg chamber, and its maintenance in this posterior location. This is the first sign of anterior-posterior asymmetry in the developing egg chamber. + GOC:mtg_sensu + PMID:10449356 + + + + + oocyte localisation involved in germarium-derived egg chamber formation + GOC:mah + + + + + oocyte localization during germarium-derived egg chamber formation + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the prostate gland over time, from its formation to the mature structure. The prostate gland is a partly muscular, partly glandular body that is situated near the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid. + prostate development + biological_process + GO:0030850 + prostate gland development + + + + + The process whose specific outcome is the progression of the prostate gland over time, from its formation to the mature structure. The prostate gland is a partly muscular, partly glandular body that is situated near the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid. + PMID:11839751 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium. + biological_process + GO:0030855 + epithelial cell differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium. + GOC:ecd + PMID:11839751 + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of epithelial cell differentiation. + biological_process + GO:0030856 + regulation of epithelial cell differentiation + + + + + Any process that modulates the frequency, rate or extent of epithelial cell differentiation. + GOC:mah + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell differentiation. + down regulation of epithelial cell differentiation + down-regulation of epithelial cell differentiation + downregulation of epithelial cell differentiation + inhibition of epithelial cell differentiation + biological_process + GO:0030857 + negative regulation of epithelial cell differentiation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell differentiation. + GOC:mah + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation. + up regulation of epithelial cell differentiation + up-regulation of epithelial cell differentiation + upregulation of epithelial cell differentiation + activation of epithelial cell differentiation + stimulation of epithelial cell differentiation + biological_process + GO:0030858 + positive regulation of epithelial cell differentiation + + + + + Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the thyroid gland over time, from its formation to the mature structure. The thyroid gland is an endoderm-derived gland that produces thyroid hormone. + biological_process + GO:0030878 + thyroid gland development + + + + + The process whose specific outcome is the progression of the thyroid gland over time, from its formation to the mature structure. The thyroid gland is an endoderm-derived gland that produces thyroid hormone. + GOC:dgh + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the mammary gland over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. Its development starts with the formation of the mammary line and ends as the mature gland cycles between nursing and weaning stages. + mammogenesis + biological_process + GO:0030879 + mammary gland development + + + + + The process whose specific outcome is the progression of the mammary gland over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. Its development starts with the formation of the mammary line and ends as the mature gland cycles between nursing and weaning stages. + PMID:9576833 + + + + + mammogenesis + GOC:dph + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency or rate of myeloid dendritic cell activation. + biological_process + GO:0030885 + regulation of myeloid dendritic cell activation + + + + + Any process that modulates the frequency or rate of myeloid dendritic cell activation. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid dendritic cell activation. + down regulation of myeloid dendritic cell activation + down-regulation of myeloid dendritic cell activation + downregulation of myeloid dendritic cell activation + inhibition of myeloid dendritic cell activation + biological_process + GO:0030886 + negative regulation of myeloid dendritic cell activation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid dendritic cell activation. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that stimulates, induces or increases the rate of myeloid dendritic cell activation. + up regulation of myeloid dendritic cell activation + up-regulation of myeloid dendritic cell activation + upregulation of myeloid dendritic cell activation + activation of myeloid dendritic cell activation + stimulation of myeloid dendritic cell activation + biological_process + GO:0030887 + positive regulation of myeloid dendritic cell activation + + + + + Any process that stimulates, induces or increases the rate of myeloid dendritic cell activation. + GOC:mah + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of B cell proliferation. + regulation of B lymphocyte proliferation + regulation of B-cell proliferation + regulation of B-lymphocyte proliferation + biological_process + GO:0030888 + regulation of B cell proliferation + + + + + Any process that modulates the frequency, rate or extent of B cell proliferation. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the rate or extent of B cell proliferation. + down regulation of B cell proliferation + down-regulation of B cell proliferation + downregulation of B cell proliferation + negative regulation of B lymphocyte proliferation + negative regulation of B-cell proliferation + negative regulation of B-lymphocyte proliferation + inhibition of B cell proliferation + biological_process + GO:0030889 + negative regulation of B cell proliferation + + + + + Any process that stops, prevents or reduces the rate or extent of B cell proliferation. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the rate or extent of B cell proliferation. + positive regulation of B lymphocyte proliferation + positive regulation of B-cell proliferation + positive regulation of B-lymphocyte proliferation + up regulation of B cell proliferation + up-regulation of B cell proliferation + upregulation of B cell proliferation + activation of B cell proliferation + stimulation of B cell proliferation + biological_process + GO:0030890 + positive regulation of B cell proliferation + + + + + Any process that activates or increases the rate or extent of B cell proliferation. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the forebrain over time, from its formation to the mature structure. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions). + prosencephalon development + biological_process + GO:0030900 + forebrain development + + + + + The process whose specific outcome is the progression of the forebrain over time, from its formation to the mature structure. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions). + http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=forebrain + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the midbrain over time, from its formation to the mature structure. The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles). + mesencephalon development + biological_process + GO:0030901 + midbrain development + + + + + The process whose specific outcome is the progression of the midbrain over time, from its formation to the mature structure. The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles). + http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=midbrain + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the hindbrain over time, from its formation to the mature structure. The hindbrain is the posterior of the three primary divisions of the developing chordate brain, or the corresponding part of the adult brain (in vertebrates, includes the cerebellum, pons, and medulla oblongata and controls the autonomic functions and equilibrium). + rhombencephalon development + biological_process + GO:0030902 + hindbrain development + + + + + The process whose specific outcome is the progression of the hindbrain over time, from its formation to the mature structure. The hindbrain is the posterior of the three primary divisions of the developing chordate brain, or the corresponding part of the adult brain (in vertebrates, includes the cerebellum, pons, and medulla oblongata and controls the autonomic functions and equilibrium). + http://www2.merriam-webster.com/cgi-bin/mwmednlm?book=Medical&va=hindbrain + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the notochord over time, from its formation to the mature structure. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column. + biological_process + GO:0030903 + notochord development + + + + + The process whose specific outcome is the progression of the notochord over time, from its formation to the mature structure. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column. + GOC:dgh + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The formation of a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity. + biological_process + GO:0030910 + olfactory placode formation + + + + + The formation of a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity. + GOC:dgh + + + + + + + + + + + + + + + + + + + + + + + + + + + The process resulting in the transition of the otic placode into the otic vesicle, a transient embryonic structure formed during development of the vertebrate inner ear. + otocyst biosynthesis + otocyst formation + biological_process + GO:0030916 + otic vesicle formation + + + + + The process resulting in the transition of the otic placode into the otic vesicle, a transient embryonic structure formed during development of the vertebrate inner ear. + GOC:dgh + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the midbrain-hindbrain boundary over time, from its formation to the mature structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. + MHB development + isthmic organizer development + isthmomesencephalic boundary development + isthmus development + midbrain-hindbrain orgainizer development + biological_process + GO:0030917 + midbrain-hindbrain boundary development + + + + + The process whose specific outcome is the progression of the midbrain-hindbrain boundary over time, from its formation to the mature structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. + GOC:dgh + + + + + + + + + + + + + + + + + + + + Any collagen trimer that passes through a lipid bilayer membrane. + MACIT + cellular_component + GO:0030936 + transmembrane collagen trimer + + + + + Any collagen trimer that passes through a lipid bilayer membrane. + ISBN:0721639976 + + + + + MACIT + ISBN:0198599587 + + + + + + + + + + Any cellular process that results in the specification, formation or maintenance of polarized microtubule-based cytoskeletal structures. + biological_process + GO:0030951 + establishment or maintenance of microtubule cytoskeleton polarity + + + + + Any cellular process that results in the specification, formation or maintenance of polarized microtubule-based cytoskeletal structures. + GOC:mah + + + + + + + + + + Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures. + biological_process + cytoskeleton polarization + GO:0030952 + establishment or maintenance of cytoskeleton polarity + + + + + Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures. + GOC:mah + + + + + + + + + + + + + + + A nonmembrane-bound oligomeric protein complex that participates in bidirectional transport of molecules (cargo) along axonemal microtubules. + intraflagellar transport complex + intraflagellar transport particle + cellular_component + IFT complex + GO:0030990 + + Note that we deem cilia and microtubule-based flagella to be equivalent. + intraciliary transport particle + + + + + A nonmembrane-bound oligomeric protein complex that participates in bidirectional transport of molecules (cargo) along axonemal microtubules. + GOC:cilia + GOC:kmv + PMID:14570576 + PMID:22118932 + PMID:23945166 + + + + + + + + + + + A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues. + GO:0005578 + NIF_Subcellular:nlx_subcell_20090513 + Wikipedia:Extracellular_matrix + proteinaceous extracellular matrix + matrisome + cellular_component + GO:0031012 + + + + + + extracellular matrix + + + + + A structure lying external to one or more cells, which provides structural support, biochemical or biomechanical cues for cells or tissues. + GOC:BHF + GOC:mah + GOC:rph + NIF_Subcellular:nlx_subcell_20090513 + PMID:21123617 + PMID:28089324 + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the pancreas over time, from its formation to the mature structure. The pancreas is an endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating enzymes. + Wikipedia:Pancreas + biological_process + GO:0031016 + pancreas development + + + + + The process whose specific outcome is the progression of the pancreas over time, from its formation to the mature structure. The pancreas is an endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating enzymes. + GOC:cvs + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the exocrine pancreas over time, from its formation to the mature structure. The exocrine pancreas produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells. + biological_process + GO:0031017 + exocrine pancreas development + + + + + The process whose specific outcome is the progression of the exocrine pancreas over time, from its formation to the mature structure. The exocrine pancreas produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells. + GOC:cvs + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the endocrine pancreas over time, from its formation to the mature structure. The endocrine pancreas is made up of islet cells that produce insulin, glucagon and somatostatin. + biological_process + GO:0031018 + endocrine pancreas development + + + + + The process whose specific outcome is the progression of the endocrine pancreas over time, from its formation to the mature structure. The endocrine pancreas is made up of islet cells that produce insulin, glucagon and somatostatin. + GOC:cvs + + + + + + + + + + + + + + + + + + + + The directed movement of the nucleus along microfilaments within the cell, mediated by motor proteins. + nuclear migration, microfilament-mediated + biological_process + GO:0031022 + nuclear migration along microfilament + + + + + The directed movement of the nucleus along microfilaments within the cell, mediated by motor proteins. + GOC:mah + + + + + + + + + + + + + + + + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin. The myosin may be organized into filaments. + actomyosin organization + actomyosin structure organisation + biological_process + actomyosin structure organization and biogenesis + GO:0031032 + Note that this term is a child of 'actin cytoskeleton organization and biogenesis ; GO:0030036' because the actin cytoskeleton is defined as actin filaments and associated proteins. + actomyosin structure organization + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin. The myosin may be organized into filaments. + GOC:dph + GOC:jl + GOC:mah + + + + + actomyosin structure organization and biogenesis + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the hair follicle are generated and organized. + biological_process + GO:0031069 + hair follicle morphogenesis + + + + + The process in which the anatomical structures of the hair follicle are generated and organized. + GOC:ln + + + + + + + + + + The process occurring during the embryonic phase whose specific outcome is the progression of the eye over time, from its formation to the mature structure. + embryonic eye development + biological_process + GO:0031076 + embryonic camera-type eye development + + + + + The process occurring during the embryonic phase whose specific outcome is the progression of the eye over time, from its formation to the mature structure. + GOC:mah + GOC:mtg_sensu + + + + + + + + + + + + + + + + + + + A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle. + NIF_Subcellular:sao830981606 + cellular_component + intracellular membrane + GO:0031090 + organelle membrane + + + + + A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle. + GOC:dos + GOC:mah + + + + + intracellular membrane + NIF_Subcellular:sao830981606 + + + + + + + + + + The regrowth of a lost or destroyed body part, such as an organ or tissue. This process may occur via renewal, repair, and/or growth alone (i.e. increase in size or mass). + Wikipedia:Regeneration_(biology) + biological_process + GO:0031099 + regeneration + + + + + The regrowth of a lost or destroyed body part, such as an organ or tissue. This process may occur via renewal, repair, and/or growth alone (i.e. increase in size or mass). + GOC:mah + GOC:pr + + + + + + + + + + + + + + + + + + + + + The regrowth of a lost or destroyed animal organ. + biological_process + GO:0031100 + animal organ regeneration + + + + + The regrowth of a lost or destroyed animal organ. + GOC:mah + + + + + + + + + + + + + + + + + + + + The regrowth of fin tissue following its loss or destruction. + biological_process + GO:0031101 + fin regeneration + + + + + The regrowth of fin tissue following its loss or destruction. + GOC:dgh + + + + + + + + + Assembly or disassembly of microtubules by the addition or removal of tubulin heterodimers from a microtubule. + biological_process + GO:0031109 + microtubule polymerization or depolymerization + + + + + Assembly or disassembly of microtubules by the addition or removal of tubulin heterodimers from a microtubule. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of microtubule polymerization or depolymerization by the addition or removal of tubulin heterodimers from a microtubule. + biological_process + GO:0031110 + regulation of microtubule polymerization or depolymerization + + + + + Any process that modulates the frequency, rate or extent of microtubule polymerization or depolymerization by the addition or removal of tubulin heterodimers from a microtubule. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization or depolymerization. + down regulation of microtubule polymerization or depolymerization + down-regulation of microtubule polymerization or depolymerization + downregulation of microtubule polymerization or depolymerization + inhibition of microtubule polymerization or depolymerization + biological_process + GO:0031111 + negative regulation of microtubule polymerization or depolymerization + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization or depolymerization. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of microtubule polymerization or depolymerization. + up regulation of microtubule polymerization or depolymerization + up-regulation of microtubule polymerization or depolymerization + upregulation of microtubule polymerization or depolymerization + activation of microtubule polymerization or depolymerization + stimulation of microtubule polymerization or depolymerization + biological_process + GO:0031112 + positive regulation of microtubule polymerization or depolymerization + + + + + Any process that activates or increases the frequency, rate or extent of microtubule polymerization or depolymerization. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of microtubule polymerization. + biological_process + GO:0031113 + regulation of microtubule polymerization + + + + + Any process that modulates the frequency, rate or extent of microtubule polymerization. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization. + down regulation of microtubule polymerization + down-regulation of microtubule polymerization + downregulation of microtubule polymerization + inhibition of microtubule polymerization + biological_process + GO:0031115 + negative regulation of microtubule polymerization + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of microtubule polymerization. + up regulation of microtubule polymerization + up-regulation of microtubule polymerization + upregulation of microtubule polymerization + activation of microtubule polymerization + stimulation of microtubule polymerization + biological_process + GO:0031116 + positive regulation of microtubule polymerization + + + + + Any process that activates or increases the frequency, rate or extent of microtubule polymerization. + GOC:mah + + + + + + + + + + + + + + + + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell. + cytoplasmic microtubule organisation + biological_process + cytoplasmic microtubule organization and biogenesis + GO:0031122 + cytoplasmic microtubule organization + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell. + GOC:mah + + + + + cytoplasmic microtubule organization and biogenesis + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A developmental process involving two tissues in which one tissue (the inducer) produces a signal that directs cell fate commitment of cells in the second tissue (the responder). + + biological_process + GO:0031128 + developmental induction + + + + + A developmental process involving two tissues in which one tissue (the inducer) produces a signal that directs cell fate commitment of cells in the second tissue (the responder). + GOC:cjm + GOC:dph + GOC:mah + PMID:24503535 + + + + + + + + + + + + + + + + + + + The component of the vacuolar membrane consisting of gene products and protein complexes that have some part that penetrates at least one leaflet of the membrane bilayer. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. + integral to vacuolar membrane + cellular_component + GO:0031166 + integral component of vacuolar membrane + + + + + The component of the vacuolar membrane consisting of gene products and protein complexes that have some part that penetrates at least one leaflet of the membrane bilayer. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. + GOC:dos + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). + neurite biosynthesis + neurite development + neurite formation + neurite growth + neurite outgrowth + biological_process + GO:0031175 + neuron projection development + + + + + The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites). + GOC:mah + + + + + neurite development + GOC:dph + + + + + + + + + + + + + + + + Formation of hard tissues that consist mainly of inorganic compounds, and also contain a small amounts of organic matrices that are believed to play important roles in their formation. + Wikipedia:Biomineralization + biological_process + GO:0031214 + biomineral tissue development + + + + + Formation of hard tissues that consist mainly of inorganic compounds, and also contain a small amounts of organic matrices that are believed to play important roles in their formation. + PMID:15132736 + + + + + + + + + + + + + + + The component of a membrane consisting of the gene products having some covalently attached portion, for example part of a peptide sequence or some other covalently attached group such as a GPI anchor, which spans or is embedded in one or both leaflets of the membrane. + intrinsic to membrane + cellular_component + GO:0031224 + + Note that proteins intrinsic to membranes cannot be removed without disrupting the membrane, e.g. by detergent. + intrinsic component of membrane + + + + + The component of a membrane consisting of the gene products having some covalently attached portion, for example part of a peptide sequence or some other covalently attached group such as a GPI anchor, which spans or is embedded in one or both leaflets of the membrane. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + The component of the plasma membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. + intrinsic to plasma membrane + cellular_component + GO:0031226 + intrinsic component of plasma membrane + + + + + The component of the plasma membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. + GOC:dos + GOC:mah + + + + + + + + + + + + + + + + + + + The component of the Golgi membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. + intrinsic to Golgi membrane + cellular_component + GO:0031228 + intrinsic component of Golgi membrane + + + + + The component of the Golgi membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. + GOC:dos + GOC:mah + + + + + + + + + + + + + + + The area of a motile cell closest to the direction of movement. + front of cell + leading edge of cell + cellular_component + GO:0031252 + + cell leading edge + + + + + The area of a motile cell closest to the direction of movement. + GOC:pg + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The portion of the plasma membrane surrounding a plasma membrane bounded cell surface projection. + cellular_component + membrane extension + membrane projection + GO:0031253 + cell projection membrane + + + + + The portion of the plasma membrane surrounding a plasma membrane bounded cell surface projection. + GOC:krc + GOC:mah + + + + + + + + + + + + + + + + + + + + + The portion of the plasma membrane surrounding the leading edge of a motile cell. + cellular_component + GO:0031256 + leading edge membrane + + + + + The portion of the plasma membrane surrounding the leading edge of a motile cell. + GOC:mah + + + + + + + + + + + + + + + + + + + The component of the organelle membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. + intrinsic to organelle membrane + cellular_component + GO:0031300 + intrinsic component of organelle membrane + + + + + The component of the organelle membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. + GOC:dos + GOC:mah + + + + + + + + + + + + + + + + + + + + The component of the organelle membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. + integral to organelle membrane + cellular_component + GO:0031301 + integral component of organelle membrane + + + + + The component of the organelle membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. + GOC:dos + GOC:mah + + + + + + + + + + + + + + + + + + + The component of the nuclear outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. + intrinsic to nuclear outer membrane + cellular_component + GO:0031308 + intrinsic component of nuclear outer membrane + + + + + The component of the nuclear outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. + GOC:dos + GOC:mah + + + + + + + + + + + + + + + + + + + The component of the nuclear outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. + integral to nuclear outer membrane + cellular_component + GO:0031309 + integral component of nuclear outer membrane + + + + + The component of the nuclear outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. + GOC:dos + GOC:mah + + + + + + + + + + + + + + + + + + + The component of the vacuolar membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. + intrinsic to vacuolar membrane + cellular_component + GO:0031310 + intrinsic component of vacuolar membrane + + + + + The component of the vacuolar membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane. + GOC:dos + GOC:mah + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. + regulation of cellular metabolism + biological_process + GO:0031323 + + regulation of cellular metabolic process + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. + down regulation of cellular metabolic process + down-regulation of cellular metabolic process + downregulation of cellular metabolic process + negative regulation of cellular metabolism + inhibition of cellular metabolic process + biological_process + GO:0031324 + + negative regulation of cellular metabolic process + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. + positive regulation of cellular metabolism + up regulation of cellular metabolic process + up-regulation of cellular metabolic process + upregulation of cellular metabolic process + activation of cellular metabolic process + stimulation of cellular metabolic process + biological_process + GO:0031325 + + positive regulation of cellular metabolic process + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances. + GOC:mah + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. + regulation of cellular anabolism + regulation of cellular biosynthesis + regulation of cellular formation + regulation of cellular synthesis + biological_process + GO:0031326 + regulation of cellular biosynthetic process + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. + down regulation of cellular biosynthetic process + down-regulation of cellular biosynthetic process + downregulation of cellular biosynthetic process + negative regulation of cellular anabolism + negative regulation of cellular biosynthesis + negative regulation of cellular formation + negative regulation of cellular synthesis + inhibition of cellular biosynthetic process + biological_process + GO:0031327 + negative regulation of cellular biosynthetic process + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. + positive regulation of cellular anabolism + positive regulation of cellular biosynthesis + positive regulation of cellular formation + positive regulation of cellular synthesis + up regulation of cellular biosynthetic process + up-regulation of cellular biosynthetic process + upregulation of cellular biosynthetic process + activation of cellular biosynthetic process + stimulation of cellular biosynthetic process + biological_process + GO:0031328 + positive regulation of cellular biosynthetic process + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. + GOC:mah + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells. + regulation of cellular breakdown + regulation of cellular catabolism + regulation of cellular degradation + biological_process + GO:0031329 + regulation of cellular catabolic process + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells. + down regulation of cellular catabolic process + down-regulation of cellular catabolic process + downregulation of cellular catabolic process + negative regulation of cellular breakdown + negative regulation of cellular catabolism + negative regulation of cellular degradation + inhibition of cellular catabolic process + biological_process + GO:0031330 + negative regulation of cellular catabolic process + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells. + positive regulation of cellular breakdown + positive regulation of cellular catabolism + positive regulation of cellular degradation + up regulation of cellular catabolic process + up-regulation of cellular catabolic process + upregulation of cellular catabolic process + activation of cellular catabolic process + stimulation of cellular catabolic process + biological_process + GO:0031331 + positive regulation of cellular catabolic process + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly. + down regulation of protein complex assembly + down-regulation of protein complex assembly + downregulation of protein complex assembly + inhibition of protein complex assembly + biological_process + negative regulation of protein complex assembly + GO:0031333 + negative regulation of protein-containing complex assembly + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of protein complex assembly. + up regulation of protein complex assembly + up-regulation of protein complex assembly + upregulation of protein complex assembly + activation of protein complex assembly + stimulation of protein complex assembly + biological_process + positive regulation of protein complex assembly + GO:0031334 + positive regulation of protein-containing complex assembly + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that activates or increases the frequency, rate or extent of protein complex assembly. + GOC:mah + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of vesicle fusion. + biological_process + GO:0031338 + regulation of vesicle fusion + + + + + Any process that modulates the frequency, rate or extent of vesicle fusion. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of vesicle fusion. + down regulation of vesicle fusion + down-regulation of vesicle fusion + downregulation of vesicle fusion + inhibition of vesicle fusion + biological_process + GO:0031339 + negative regulation of vesicle fusion + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of vesicle fusion. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of vesicle fusion. + up regulation of vesicle fusion + up-regulation of vesicle fusion + upregulation of vesicle fusion + activation of vesicle fusion + stimulation of vesicle fusion + biological_process + GO:0031340 + positive regulation of vesicle fusion + + + + + Any process that activates or increases the frequency, rate or extent of vesicle fusion. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections. + regulation of cell projection organisation + biological_process + regulation of cell projection organization and biogenesis + GO:0031344 + regulation of cell projection organization + + + + + Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections. + GOC:mah + + + + + regulation of cell projection organization and biogenesis + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections. + down regulation of cell projection organization + down-regulation of cell projection organization + downregulation of cell projection organization + negative regulation of cell projection organisation + inhibition of cell projection organization + biological_process + negative regulation of cell projection organization and biogenesis + GO:0031345 + negative regulation of cell projection organization + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections. + GOC:mah + + + + + down regulation of cell projection organization + GOC:mah + + + + + negative regulation of cell projection organization and biogenesis + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the process involved in the formation, arrangement of constituent parts, or disassembly of cell projections. + positive regulation of cell projection organisation + up regulation of cell projection organization + up-regulation of cell projection organization + upregulation of cell projection organization + activation of cell projection organization + stimulation of cell projection organization + biological_process + positive regulation of cell projection organization and biogenesis + GO:0031346 + positive regulation of cell projection organization + + + + + Any process that activates or increases the frequency, rate or extent of the process involved in the formation, arrangement of constituent parts, or disassembly of cell projections. + GOC:mah + + + + + positive regulation of cell projection organization and biogenesis + GOC:mah + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of a defense response. + biological_process + GO:0031347 + regulation of defense response + + + + + Any process that modulates the frequency, rate or extent of a defense response. + GOC:mah + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response. + down regulation of defense response + down-regulation of defense response + downregulation of defense response + inhibition of defense response + biological_process + GO:0031348 + negative regulation of defense response + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response. + GOC:mah + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of a defense response. + up regulation of defense response + up-regulation of defense response + upregulation of defense response + activation of defense response + stimulation of defense response + biological_process + GO:0031349 + positive regulation of defense response + + + + + Any process that activates or increases the frequency, rate or extent of a defense response. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein. + biological_process + GO:0031399 + + regulation of protein modification process + + + + + Any process that modulates the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein. + GOC:mah + GOC:tb + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein. + down regulation of protein modification + down-regulation of protein modification + downregulation of protein modification + inhibition of protein modification + biological_process + GO:0031400 + negative regulation of protein modification process + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein. + GOC:mah + GOC:tb + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein. + up regulation of protein modification + up-regulation of protein modification + upregulation of protein modification + activation of protein modification + stimulation of protein modification + biological_process + GO:0031401 + positive regulation of protein modification process + + + + + Any process that activates or increases the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein. + GOC:mah + GOC:tb + + + + + + + + + + + + + + + + + + + Binding to a sodium ion (Na+). + Na+ ion binding + molecular_function + GO:0031402 + sodium ion binding + + + + + Binding to a sodium ion (Na+). + GOC:mah + + + + + + + + + + + + + + + + + + + Binding to a carboxylic acid, an organic acid containing one or more carboxyl (COOH) groups or anions (COO-). + molecular_function + GO:0031406 + + carboxylic acid binding + + + + + Binding to a carboxylic acid, an organic acid containing one or more carboxyl (COOH) groups or anions (COO-). + GOC:mah + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + + + + + + + A vesicle found in the cytoplasm of a cell. + GO:0016023 + NIF_Subcellular:sao180601769 + cellular_component + cytoplasmic membrane bounded vesicle + cytoplasmic membrane-enclosed vesicle + cytoplasmic, membrane-bounded vesicle + GO:0031410 + + + + + + + cytoplasmic vesicle + + + + + A vesicle found in the cytoplasm of a cell. + GOC:ai + GOC:mah + GOC:vesicles + + + + + + + + + + + + + + + + + + + Any process that modulates an organism's tendency or ability to rise or float in a fluid medium such as water or air, often through the use of stored gases. + buoyancy regulation + biological_process + GO:0031413 + regulation of buoyancy + + + + + Any process that modulates an organism's tendency or ability to rise or float in a fluid medium such as water or air, often through the use of stored gases. + GOC:mah + PATO:0001420 + + + + + + + + + + + + + + + + + + + + + The process in which the cytoplasm of the outermost cells of the vertebrate epidermis is replaced by keratin. Keratinization occurs in the stratum corneum, feathers, hair, claws, nails, hooves, and horns. + biological_process + GO:0031424 + keratinization + + + + + The process in which the cytoplasm of the outermost cells of the vertebrate epidermis is replaced by keratin. Keratinization occurs in the stratum corneum, feathers, hair, claws, nails, hooves, and horns. + GOC:dph + GOC:ebc + GOC:sdb_2009 + GOC:tb + + + + + + + + + + + + + + + + + + + A localization process that acts on a protein complex; the complex is transported to, or maintained in, a specific location. + https://github.com/geneontology/go-ontology/issues/22021 + GO:0034629 + establishment and maintenance of protein complex localization + protein complex localisation + biological_process + cellular protein complex localisation + cellular protein complex localization + cellular protein-containing complex localization + establishment and maintenance of cellular protein complex localization + protein complex localization + GO:0031503 + protein-containing complex localization + + + + + A localization process that acts on a protein complex; the complex is transported to, or maintained in, a specific location. + GOC:mah + + + + + protein complex localisation + GOC:mah + + + + + cellular protein complex localisation + GOC:mah + + + + + + + + + + + + + + + + + + + + A cilium which may have a variable arrangement of axonemal microtubules and also contains molecular motors. It may beat with a whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface, such as on epithelial cells that line the lumenal ducts of various tissues; or they may display a distinct twirling motion that directs fluid flow asymmetrically across the cellular surface to affect asymmetric body plan organization. Motile cilia can be found in single as well as multiple copies per cell. + GO:0009434 + GO:0031512 + motile cilia + cellular_component + microtubule-based flagellum + motile primary cilia + motile primary cilium + motile secondary cilium + nodal cilium + GO:0031514 + motile cilium + + + + + A cilium which may have a variable arrangement of axonemal microtubules and also contains molecular motors. It may beat with a whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface, such as on epithelial cells that line the lumenal ducts of various tissues; or they may display a distinct twirling motion that directs fluid flow asymmetrically across the cellular surface to affect asymmetric body plan organization. Motile cilia can be found in single as well as multiple copies per cell. + GOC:cilia + GOC:dgh + GOC:kmv + PMID:17009929 + PMID:20144998 + PMID:22118931 + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons. + biological_process + GO:0031641 + regulation of myelination + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons. + GOC:mah + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a myelin sheath around nerve axons. + down regulation of myelination + down-regulation of myelination + downregulation of myelination + inhibition of myelination + biological_process + GO:0031642 + negative regulation of myelination + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a myelin sheath around nerve axons. + GOC:mah + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the formation of a myelin sheath around nerve axons. + up regulation of myelination + up-regulation of myelination + upregulation of myelination + activation of myelination + stimulation of myelination + biological_process + GO:0031643 + positive regulation of myelination + + + + + Any process that activates or increases the frequency, rate or extent of the formation of a myelin sheath around nerve axons. + GOC:mah + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of the nervous system. + regulation of neurological process + regulation of neurological system process + regulation of neurophysiological process + biological_process + GO:0031644 + regulation of nervous system process + + + + + Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of the nervous system. + GOC:dph + GOC:mah + GOC:tb + + + + + regulation of neurological process + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of a neurophysiological process. + down regulation of neurological process + down-regulation of neurological process + downregulation of neurological process + negative regulation of neurological process + negative regulation of neurological system process + negative regulation of neurophysiological process + inhibition of neurological process + biological_process + GO:0031645 + negative regulation of nervous system process + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of a neurophysiological process. + GOC:dph + GOC:mah + GOC:tb + + + + + negative regulation of neurological process + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of a neurophysiological process. + positive regulation of neurological process + positive regulation of neurological system process + positive regulation of neurophysiological process + up regulation of neurological process + up-regulation of neurological process + upregulation of neurological process + activation of neurological process + stimulation of neurological process + biological_process + GO:0031646 + positive regulation of nervous system process + + + + + Any process that activates or increases the frequency, rate or extent of a neurophysiological process. + GOC:dph + GOC:mah + GOC:tb + + + + + positive regulation of neurological process + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids. + regulation of glucocorticoid metabolism + biological_process + GO:0031943 + regulation of glucocorticoid metabolic process + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids. + down regulation of glucocorticoid metabolic process + down-regulation of glucocorticoid metabolic process + downregulation of glucocorticoid metabolic process + negative regulation of glucocorticoid metabolism + inhibition of glucocorticoid metabolic process + biological_process + GO:0031944 + negative regulation of glucocorticoid metabolic process + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids. + positive regulation of glucocorticoid metabolism + up regulation of glucocorticoid metabolic process + up-regulation of glucocorticoid metabolic process + upregulation of glucocorticoid metabolic process + activation of glucocorticoid metabolic process + stimulation of glucocorticoid metabolic process + biological_process + GO:0031945 + positive regulation of glucocorticoid metabolic process + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids. + GOC:mah + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids. + biological_process + GO:0031946 + regulation of glucocorticoid biosynthetic process + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids. + down regulation of glucocorticoid biosynthetic process + down-regulation of glucocorticoid biosynthetic process + downregulation of glucocorticoid biosynthetic process + inhibition of glucocorticoid biosynthetic process + biological_process + GO:0031947 + negative regulation of glucocorticoid biosynthetic process + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids. + up regulation of glucocorticoid biosynthetic process + up-regulation of glucocorticoid biosynthetic process + upregulation of glucocorticoid biosynthetic process + activation of glucocorticoid biosynthetic process + stimulation of glucocorticoid biosynthetic process + biological_process + GO:0031948 + positive regulation of glucocorticoid biosynthetic process + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids. + GOC:mah + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids. + biological_process + GO:0031949 + regulation of glucocorticoid catabolic process + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids. + GOC:mah + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids. + down regulation of glucocorticoid catabolic process + down-regulation of glucocorticoid catabolic process + downregulation of glucocorticoid catabolic process + inhibition of glucocorticoid catabolic process + biological_process + GO:0031950 + negative regulation of glucocorticoid catabolic process + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids. + GOC:mah + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids. + up regulation of glucocorticoid catabolic process + up-regulation of glucocorticoid catabolic process + upregulation of glucocorticoid catabolic process + activation of glucocorticoid catabolic process + stimulation of glucocorticoid catabolic process + biological_process + GO:0031951 + positive regulation of glucocorticoid catabolic process + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids. + GOC:mah + + + + + + + + + + The series of molecular signals initiated by corticosteroid binding to its receptor, and ending with the regulation of a downstream cellular process, e.g. transcription. + corticosteroid receptor signalling pathway + biological_process + GO:0031958 + corticosteroid receptor signaling pathway + + + + + The series of molecular signals initiated by corticosteroid binding to its receptor, and ending with the regulation of a downstream cellular process, e.g. transcription. + GOC:mah + PMID:11027914 + PMID:12606724 + + + + + + + + + + + + + + + + + + + + + + + + + Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space. + NIF_Subcellular:sao1687101204 + cellular_component + GO:0031965 + nuclear membrane + + + + + Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space. + GOC:mah + GOC:pz + + + + + + + + + + + + + + + + + + + + + A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes. + cellular_component + GO:0031967 + + organelle envelope + + + + + A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes. + GOC:mah + GOC:pz + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The outer, i.e. cytoplasm-facing in a cellular organelle, lipid bilayer of an organelle envelope. + cellular_component + GO:0031968 + organelle outer membrane + + + + + The outer, i.e. cytoplasm-facing in a cellular organelle, lipid bilayer of an organelle envelope. + GOC:mah + + + + + + + + + + + + + + + A multilayered structure surrounding all or part of a cell; encompasses one or more lipid bilayers, and may include a cell wall layer; also includes the space between layers. + cellular_component + GO:0031975 + envelope + + + + + A multilayered structure surrounding all or part of a cell; encompasses one or more lipid bilayers, and may include a cell wall layer; also includes the space between layers. + GOC:mah + GOC:pz + + + + + + + + + Any small, fluid-filled, spherical organelle enclosed by membrane. + GO:0031988 + NIF_Subcellular:sao221389602 + Wikipedia:Vesicle_(biology) + cellular_component + membrane-bounded vesicle + membrane-enclosed vesicle + GO:0031982 + + vesicle + + + + + Any small, fluid-filled, spherical organelle enclosed by membrane. + GOC:mah + GOC:pz + GOC:vesicles + + + + + + + + + + + + + + + + + + + + Self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement. + locomotion during locomotory behaviour + biological_process + GO:0031987 + locomotion involved in locomotory behavior + + + + + Self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the regulated release of insulin. + up regulation of insulin secretion + up-regulation of insulin secretion + upregulation of insulin secretion + activation of insulin secretion + stimulation of insulin secretion + biological_process + GO:0032024 + positive regulation of insulin secretion + + + + + Any process that activates or increases the frequency, rate or extent of the regulated release of insulin. + GOC:mah + + + + + + + + + + + + + + + + + + + Binding to a bile acid, a steroid carboxylic acids occurring in bile. + molecular_function + GO:0032052 + bile acid binding + + + + + Binding to a bile acid, a steroid carboxylic acids occurring in bile. + GOC:rph + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding. + down regulation of protein binding + down-regulation of protein binding + downregulation of protein binding + inhibition of protein binding + biological_process + GO:0032091 + negative regulation of protein binding + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of protein binding. + up regulation of protein binding + up-regulation of protein binding + upregulation of protein binding + activation of protein binding + stimulation of protein binding + biological_process + GO:0032092 + positive regulation of protein binding + + + + + Any process that activates or increases the frequency, rate or extent of protein binding. + GOC:mah + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of a response to an external stimulus. + biological_process + GO:0032101 + + Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. + regulation of response to external stimulus + + + + + Any process that modulates the frequency, rate or extent of a response to an external stimulus. + GOC:mah + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an external stimulus. + down regulation of response to external stimulus + down-regulation of response to external stimulus + downregulation of response to external stimulus + inhibition of response to external stimulus + biological_process + GO:0032102 + + Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. + negative regulation of response to external stimulus + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an external stimulus. + GOC:mah + + + + + + + + + + + + + + + + + + + + + Any process that activates, maintains or increases the rate of a response to an external stimulus. + up regulation of response to external stimulus + up-regulation of response to external stimulus + upregulation of response to external stimulus + activation of response to external stimulus + stimulation of response to external stimulus + biological_process + GO:0032103 + + Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. + positive regulation of response to external stimulus + + + + + Any process that activates, maintains or increases the rate of a response to an external stimulus. + GOC:mah + + + + + + + + + Any process that initiates the activity of an inactive protein kinase. + biological_process + protein kinase activation + GO:0032147 + activation of protein kinase activity + + + + + Any process that initiates the activity of an inactive protein kinase. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the assembly of actin filament bundles. + regulation of actin cable assembly + biological_process + regulation of actin filament bundle formation + GO:0032231 + regulation of actin filament bundle assembly + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate or extent of the assembly of actin filament bundles. + GOC:mah + + + + + regulation of actin cable assembly + GOC:dph + GOC:tb + + + + + regulation of actin filament bundle formation + GOC:dph + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of actin filament bundles. + down regulation of actin filament bundle formation + down-regulation of actin filament bundle formation + downregulation of actin filament bundle formation + inhibition of actin filament bundle formation + biological_process + GO:0032232 + negative regulation of actin filament bundle assembly + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of actin filament bundles. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the assembly of actin filament bundles. + up regulation of actin filament bundle formation + up-regulation of actin filament bundle formation + upregulation of actin filament bundle formation + activation of actin filament bundle formation + stimulation of actin filament bundle formation + biological_process + GO:0032233 + positive regulation of actin filament bundle assembly + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that activates or increases the frequency, rate or extent of the assembly of actin filament bundles. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the process of creating protein polymers. + regulation of protein polymerisation + biological_process + GO:0032271 + regulation of protein polymerization + + + + + Any process that modulates the frequency, rate or extent of the process of creating protein polymers. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the process of creating protein polymers. + down regulation of protein polymerization + down-regulation of protein polymerization + downregulation of protein polymerization + inhibition of protein polymerization + biological_process + GO:0032272 + negative regulation of protein polymerization + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the process of creating protein polymers. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the process of creating protein polymers. + up regulation of protein polymerization + up-regulation of protein polymerization + upregulation of protein polymerization + activation of protein polymerization + stimulation of protein polymerization + biological_process + GO:0032273 + positive regulation of protein polymerization + + + + + Any process that activates or increases the frequency, rate or extent of the process of creating protein polymers. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the wraps of cell membrane that constitute myelin are laid down around an axon in the central or peripheral nervous system. + biological_process + myelin formation + GO:0032288 + myelin assembly + + + + + The process in which the wraps of cell membrane that constitute myelin are laid down around an axon in the central or peripheral nervous system. + GOC:dgh + GOC:dph + GOC:tb + + + + + myelin formation + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by an oligodendrocyte in the central nervous system. + myelin formation in central nervous system + biological_process + GO:0032289 + central nervous system myelin formation + + + + + The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by an oligodendrocyte in the central nervous system. + GOC:dgh + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by Schwann cells in the peripheral nervous system. + https://github.com/geneontology/go-ontology/issues/19106 + myelin formation in peripheral nervous system + biological_process + GO:0032290 + peripheral nervous system myelin formation + + + + + The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by Schwann cells in the peripheral nervous system. + GOC:dgh + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a glial cell membrane closes around an axon in the central nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction. + ensheathment of axons in central nervous system + biological_process + GO:0032291 + axon ensheathment in central nervous system + + + + + The process in which a glial cell membrane closes around an axon in the central nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction. + GOC:dgh + + + + + + + + + + + + + + + + + + + + The process in which a Schwann cell membrane closes around an axon in the peripheral nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction. + ensheathment of axons in peripheral nervous system + biological_process + GO:0032292 + peripheral nervous system axon ensheathment + + + + + The process in which a Schwann cell membrane closes around an axon in the peripheral nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction. + GOC:dgh + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of chondrocyte differentiation. + biological_process + GO:0032330 + regulation of chondrocyte differentiation + + + + + Any process that modulates the frequency, rate or extent of chondrocyte differentiation. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of chondrocyte differentiation. + down regulation of chondrocyte differentiation + down-regulation of chondrocyte differentiation + downregulation of chondrocyte differentiation + inhibition of chondrocyte differentiation + biological_process + GO:0032331 + negative regulation of chondrocyte differentiation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of chondrocyte differentiation. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of chondrocyte differentiation. + up regulation of chondrocyte differentiation + up-regulation of chondrocyte differentiation + upregulation of chondrocyte differentiation + activation of chondrocyte differentiation + stimulation of chondrocyte differentiation + biological_process + GO:0032332 + positive regulation of chondrocyte differentiation + + + + + Any process that activates or increases the frequency, rate or extent of chondrocyte differentiation. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways involving aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance. + aldosterone metabolism + biological_process + GO:0032341 + aldosterone metabolic process + + + + + The chemical reactions and pathways involving aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance. + PMID:16527843 + + + + + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance. + biological_process + GO:0032342 + aldosterone biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance. + PMID:16527843 + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance. + biological_process + GO:0032343 + aldosterone catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance. + PMID:16527843 + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving aldosterone. + regulation of aldosterone metabolism + biological_process + GO:0032344 + regulation of aldosterone metabolic process + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving aldosterone. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving aldosterone. + down regulation of aldosterone metabolic process + down-regulation of aldosterone metabolic process + downregulation of aldosterone metabolic process + negative regulation of aldosterone metabolism + inhibition of aldosterone metabolic process + biological_process + GO:0032345 + negative regulation of aldosterone metabolic process + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving aldosterone. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving aldosterone. + positive regulation of aldosterone metabolism + up regulation of aldosterone metabolic process + up-regulation of aldosterone metabolic process + upregulation of aldosterone metabolic process + activation of aldosterone metabolic process + stimulation of aldosterone metabolic process + biological_process + GO:0032346 + positive regulation of aldosterone metabolic process + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving aldosterone. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone. + biological_process + GO:0032347 + regulation of aldosterone biosynthetic process + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone. + down regulation of aldosterone biosynthetic process + down-regulation of aldosterone biosynthetic process + downregulation of aldosterone biosynthetic process + inhibition of aldosterone biosynthetic process + biological_process + GO:0032348 + negative regulation of aldosterone biosynthetic process + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone. + up regulation of aldosterone biosynthetic process + up-regulation of aldosterone biosynthetic process + upregulation of aldosterone biosynthetic process + activation of aldosterone biosynthetic process + stimulation of aldosterone biosynthetic process + biological_process + GO:0032349 + positive regulation of aldosterone biosynthetic process + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone. + GOC:mah + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any hormone. + regulation of hormone metabolism + biological_process + GO:0032350 + regulation of hormone metabolic process + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any hormone. + GOC:mah + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving any hormone. + down regulation of hormone metabolic process + down-regulation of hormone metabolic process + downregulation of hormone metabolic process + negative regulation of hormone metabolism + inhibition of hormone metabolic process + biological_process + GO:0032351 + negative regulation of hormone metabolic process + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving any hormone. + GOC:mah + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any hormone. + positive regulation of hormone metabolism + up regulation of hormone metabolic process + up-regulation of hormone metabolic process + upregulation of hormone metabolic process + activation of hormone metabolic process + stimulation of hormone metabolic process + biological_process + GO:0032352 + positive regulation of hormone metabolic process + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any hormone. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones. + down regulation of hormone biosynthetic process + down-regulation of hormone biosynthetic process + downregulation of hormone biosynthetic process + inhibition of hormone biosynthetic process + biological_process + GO:0032353 + negative regulation of hormone biosynthetic process + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones. + GOC:ai + + + + + + + + + + + + + + + + + + + + + + + The directed movement of lipids within cells. + biological_process + GO:0032365 + intracellular lipid transport + + + + + The directed movement of lipids within cells. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + biological_process + GO:0032368 + regulation of lipid transport + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + down regulation of lipid transport + down-regulation of lipid transport + downregulation of lipid transport + inhibition of lipid transport + biological_process + GO:0032369 + negative regulation of lipid transport + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + up regulation of lipid transport + up-regulation of lipid transport + upregulation of lipid transport + activation of lipid transport + stimulation of lipid transport + biological_process + GO:0032370 + positive regulation of lipid transport + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that activates or increases the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the directed movement of lipids within cells. + biological_process + GO:0032377 + regulation of intracellular lipid transport + + + + + Any process that modulates the frequency, rate or extent of the directed movement of lipids within cells. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids within cells. + down regulation of intracellular lipid transport + down-regulation of intracellular lipid transport + downregulation of intracellular lipid transport + inhibition of intracellular lipid transport + biological_process + GO:0032378 + negative regulation of intracellular lipid transport + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids within cells. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the directed movement of lipids within cells. + up regulation of intracellular lipid transport + up-regulation of intracellular lipid transport + upregulation of intracellular lipid transport + activation of intracellular lipid transport + stimulation of intracellular lipid transport + biological_process + GO:0032379 + positive regulation of intracellular lipid transport + + + + + Any process that activates or increases the frequency, rate or extent of the directed movement of lipids within cells. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the directed movement of substances within cells. + biological_process + GO:0032386 + regulation of intracellular transport + + + + + Any process that modulates the frequency, rate or extent of the directed movement of substances within cells. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells. + down regulation of intracellular transport + down-regulation of intracellular transport + downregulation of intracellular transport + inhibition of intracellular transport + biological_process + GO:0032387 + negative regulation of intracellular transport + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the directed movement of substances within cells. + up regulation of intracellular transport + up-regulation of intracellular transport + upregulation of intracellular transport + activation of intracellular transport + stimulation of intracellular transport + biological_process + GO:0032388 + positive regulation of intracellular transport + + + + + Any process that activates or increases the frequency, rate or extent of the directed movement of substances within cells. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + + An assembly of actin filaments that are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness. + GO:0000141 + GO:0030482 + cellular_component + actin cable + GO:0032432 + actin filament bundle + + + + + An assembly of actin filaments that are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness. + GOC:mah + + + + + actin cable + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Any process involved in the maintenance of an internal steady state of calcium ions within the Golgi apparatus of a cell or between the Golgi and its surroundings. + Golgi calcium ion concentration regulation + calcium ion homeostasis in Golgi + regulation of Golgi calcium ion concentration + regulation of calcium ion concentration in Golgi + biological_process + GO:0032468 + Golgi calcium ion homeostasis + + + + + Any process involved in the maintenance of an internal steady state of calcium ions within the Golgi apparatus of a cell or between the Golgi and its surroundings. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + The directed movement of calcium ions (Ca2+) into, out of or within the Golgi apparatus. + Golgi calcium transport + biological_process + GO:0032472 + Golgi calcium ion transport + + + + + The directed movement of calcium ions (Ca2+) into, out of or within the Golgi apparatus. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of an otolith are generated and organized. + biological_process + GO:0032474 + otolith morphogenesis + + + + + The process in which the anatomical structures of an otolith are generated and organized. + GOC:dgh + + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to an otolith. This process pertains to the initial formation of a structure from unspecified parts. + biological_process + GO:0032475 + otolith formation + + + + + The process that gives rise to an otolith. This process pertains to the initial formation of a structure from unspecified parts. + GOC:dgh + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Any biological process, occurring at the level of a multicellular organism, pertinent to its function. + + + + + jl + 2012-09-19T16:07:47Z + GO:0044707 + GO:0050874 + organismal physiological process + biological_process + single-multicellular organism process + GO:0032501 + + + multicellular organismal process + + + + + Any biological process, occurring at the level of a multicellular organism, pertinent to its function. + GOC:curators + GOC:dph + GOC:isa_complete + GOC:tb + + + + + + + + + + A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition. + jl + 2012-12-19T12:21:31Z + GO:0044767 + development + biological_process + single-organism developmental process + GO:0032502 + + + + developmental process + + + + + A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition. + GOC:isa_complete + + + + + + + + + + The biological process in which new individuals are produced by one or two multicellular organisms. The new individuals inherit some proportion of their genetic material from the parent or parents. + biological_process + GO:0032504 + + multicellular organism reproduction + + + + + The biological process in which new individuals are produced by one or two multicellular organisms. The new individuals inherit some proportion of their genetic material from the parent or parents. + GOC:isa_complete + GOC:jid + + + + + + + + + + + + + + + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell. + microvillus organisation + biological_process + microvillus organization and biogenesis + GO:0032528 + microvillus organization + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell. + GOC:mah + + + + + microvillus organisation + GOC:mah + + + + + microvillus organization and biogenesis + GOC:mah + + + + + + + + + + + + + + + + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus on a follicle cell. A microvillus is a thin cylindrical membrane-covered projection on the surface of an animal cell containing a core bundle of actin filaments. + follicle cell microvillus organisation + biological_process + follicle cell microvillus organization and biogenesis + GO:0032529 + follicle cell microvillus organization + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus on a follicle cell. A microvillus is a thin cylindrical membrane-covered projection on the surface of an animal cell containing a core bundle of actin filaments. + GOC:sart + PMID:16507588 + + + + + follicle cell microvillus organisation + GOC:mah + + + + + follicle cell microvillus organization and biogenesis + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus. + regulation of microvillus organisation + biological_process + regulation of microvillus organization and biogenesis + GO:0032530 + regulation of microvillus organization + + + + + Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus. + GOC:mah + + + + + regulation of microvillus organisation + GOC:mah + + + + + regulation of microvillus organization and biogenesis + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus on a follicle cell. + regulation of follicle cell microvillus organisation + biological_process + regulation of follicle cell microvillus organization and biogenesis + GO:0032531 + regulation of follicle cell microvillus organization + + + + + Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus on a follicle cell. + GOC:mah + + + + + regulation of follicle cell microvillus organisation + GOC:mah + + + + + regulation of follicle cell microvillus organization and biogenesis + GOC:mah + + + + + + + + + + + + + + + + + + + A process that modulates the formation of a microvillus. + biological_process + regulation of microvillus biogenesis + GO:0032534 + regulation of microvillus assembly + + + + + A process that modulates the formation of a microvillus. + GOC:mah + + + + + regulation of microvillus biogenesis + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus. + response to progesterone stimulus + biological_process + GO:0032570 + response to progesterone + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus. + GOC:sl + + + + + response to progesterone stimulus + GOC:dos + + + + + + + + + + + + + + + + + + + + + + + + + + + The portion of the plasma membrane surrounding a neuron projection. + cellular_component + GO:0032589 + neuron projection membrane + + + + + The portion of the plasma membrane surrounding a neuron projection. + GOC:mah + + + + + + + + + + + + + + + + + + + + The portion of the plasma membrane surrounding a dendrite. + cellular_component + GO:0032590 + dendrite membrane + + + + + The portion of the plasma membrane surrounding a dendrite. + GOC:mah + + + + + + + + + + + + + + + + + + + + + The directed movement of a protein from one location to another within a lipid bilayer. + protein translocation within membrane + receptor translocation within membrane + receptor transport within lipid bilayer + biological_process + GO:0032594 + protein transport within lipid bilayer + + + + + The directed movement of a protein from one location to another within a lipid bilayer. + GOC:mah + + + + + + + + + + + + + + + + + + + + The regulated release of bile acid, composed of any of a group of steroid carboxylic acids occurring in bile, by a cell or a tissue. + biological_process + GO:0032782 + bile acid secretion + + + + + The regulated release of bile acid, composed of any of a group of steroid carboxylic acids occurring in bile, by a cell or a tissue. + GOC:ecd + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways involving monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-). + monocarboxylate metabolic process + monocarboxylic acid metabolism + biological_process + GO:0032787 + + monocarboxylic acid metabolic process + + + + + The chemical reactions and pathways involving monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-). + GOC:vk + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the lacrimal gland over time, from its formation to the mature structure. The lacrimal gland produces secretions that lubricate and protect the cornea of the eye. + biological_process + GO:0032808 + lacrimal gland development + + + + + The process whose specific outcome is the progression of the lacrimal gland over time, from its formation to the mature structure. The lacrimal gland produces secretions that lubricate and protect the cornea of the eye. + GOC:ln + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the vertebrate kidney. The glomerulus is part of the nephron and is restricted to one body segment. + glomerular development + biological_process + GO:0032835 + glomerulus development + + + + + The progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the vertebrate kidney. The glomerulus is part of the nephron and is restricted to one body segment. + GOC:mah + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the glomerular basement membrane over time, from its formation to the mature structure. The glomerular basement membrane is the basal laminal portion of the glomerulus which performs the actual filtration. + biological_process + GO:0032836 + glomerular basement membrane development + + + + + The process whose specific outcome is the progression of the glomerular basement membrane over time, from its formation to the mature structure. The glomerular basement membrane is the basal laminal portion of the glomerulus which performs the actual filtration. + GOC:sr + + + + + + + + + + + + + + + + + + + + + + + + + + All of the contents of a plasma membrane bounded cell projection, excluding the plasma membrane surrounding the projection. + cellular_component + GO:0032838 + plasma membrane bounded cell projection cytoplasm + + + + + All of the contents of a plasma membrane bounded cell projection, excluding the plasma membrane surrounding the projection. + GOC:krc + GOC:mah + + + + + + + + + + + + + + + + + + + All of the contents of a dendrite, excluding the surrounding plasma membrane. + dendritic cytoplasm + cellular_component + GO:0032839 + dendrite cytoplasm + + + + + All of the contents of a dendrite, excluding the surrounding plasma membrane. + GOC:mah + + + + + + + + + + + + + + + + + + + + Binding to calcitonin, a peptide hormone responsible for reducing serum calcium levels by inhibiting osteoclastic bone reabsorption and promoting renal calcium excretion. It is synthesized and released by the C cells of the thyroid. + molecular_function + GO:0032841 + calcitonin binding + + + + + Binding to calcitonin, a peptide hormone responsible for reducing serum calcium levels by inhibiting osteoclastic bone reabsorption and promoting renal calcium excretion. It is synthesized and released by the C cells of the thyroid. + GOC:ecd + + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms. + response to insulin stimulus + biological_process + GO:0032868 + response to insulin + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms. + GOC:mah + ISBN:0198506732 + + + + + response to insulin stimulus + GOC:dos + + + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms. + biological_process + GO:0032869 + cellular response to insulin stimulus + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms. + GOC:mah + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus. + biological_process + GO:0032870 + cellular response to hormone stimulus + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of karyogamy, the creation of a single nucleus from multiple nuclei as a result of membrane fusion. + biological_process + GO:0032871 + regulation of karyogamy + + + + + Any process that modulates the frequency, rate or extent of karyogamy, the creation of a single nucleus from multiple nuclei as a result of membrane fusion. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns. + biological_process + GO:0032878 + regulation of establishment or maintenance of cell polarity + + + + + Any process that modulates the frequency, rate or extent of the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns. + GOC:mah + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location. + regulation of localisation + biological_process + GO:0032879 + regulation of localization + + + + + Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location. + GOC:mah + + + + + regulation of localisation + GOC:mah + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location. + https://github.com/geneontology/go-ontology/issues/22021 + jl + 2015-01-20T14:32:14Z + GO:1903827 + regulation of cellular protein localisation + regulation of cellular protein localization + regulation of protein localisation + biological_process + GO:0032880 + + regulation of protein localization + + + + + Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location. + GOC:dph + GOC:mah + GOC:tb + + + + + regulation of cellular protein localisation + GOC:TermGenie + + + + + regulation of protein localisation + GOC:mah + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving polysaccharides. + biological_process + GO:0032881 + regulation of polysaccharide metabolic process + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving polysaccharides. + GOC:mah + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chitin. + regulation of chitin metabolism + biological_process + GO:0032882 + regulation of chitin metabolic process + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chitin. + GOC:mah + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chitin. + regulation of chitin anabolism + regulation of chitin formation + regulation of chitin synthesis + biological_process + regulation of chitin biosynthesis + GO:0032883 + regulation of chitin biosynthetic process + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chitin. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides. + biological_process + GO:0032885 + regulation of polysaccharide biosynthetic process + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the microtubule cytoskeleton. + biological_process + GO:0032886 + regulation of microtubule-based process + + + + + Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the microtubule cytoskeleton. + GOC:mah + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + biological_process + GO:0032890 + regulation of organic acid transport + + + + + Any process that modulates the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:mah + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + down regulation of organic acid transport + down-regulation of organic acid transport + downregulation of organic acid transport + inhibition of organic acid transport + biological_process + GO:0032891 + negative regulation of organic acid transport + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:mah + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + up regulation of organic acid transport + up-regulation of organic acid transport + upregulation of organic acid transport + activation of organic acid transport + stimulation of organic acid transport + biological_process + GO:0032892 + positive regulation of organic acid transport + + + + + Any process that activates or increases the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:mah + + + + + + + + + + The controlled release of a substance by a cell. + Wikipedia:Secretion + cellular secretion + biological_process + GO:0032940 + secretion by cell + + + + + The controlled release of a substance by a cell. + GOC:mah + + + + + + + + + + The controlled release of a substance by a tissue. + tissue secretion + biological_process + expulsion of gland contents + GO:0032941 + secretion by tissue + + + + + The controlled release of a substance by a tissue. + GOC:mah + + + + + expulsion of gland contents + GOC:mah + + + + + + + + + + + + + + + + + + + + The expansion of a mononuclear cell population by cell division. A mononuclear cell is a leukocyte with a single non-segmented nucleus in the mature form. + PBMC proliferation + peripheral blood mononuclear cell proliferation + biological_process + GO:0032943 + mononuclear cell proliferation + + + + + The expansion of a mononuclear cell population by cell division. A mononuclear cell is a leukocyte with a single non-segmented nucleus in the mature form. + GOC:add + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of mononuclear cell proliferation. + regulation of PBMC proliferation + regulation of peripheral blood mononuclear cell proliferation + biological_process + GO:0032944 + regulation of mononuclear cell proliferation + + + + + Any process that modulates the frequency, rate or extent of mononuclear cell proliferation. + GOC:add + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of mononuclear cell proliferation. + negative regulation of PBMC proliferation + negative regulation of peripheral blood mononuclear cell proliferation + biological_process + GO:0032945 + negative regulation of mononuclear cell proliferation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of mononuclear cell proliferation. + GOC:add + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of mononuclear cell proliferation. + up regulation of mononuclear cell proliferation + up-regulation of mononuclear cell proliferation + upregulation of mononuclear cell proliferation + activation of mononuclear cell proliferation + positive regulation of PBMC proliferation + positive regulation of peripheral blood mononuclear cell proliferation + stimulation of mononuclear cell proliferation + biological_process + GO:0032946 + positive regulation of mononuclear cell proliferation + + + + + Any process that activates or increases the frequency, rate or extent of mononuclear cell proliferation. + GOC:add + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins. + regulation of actin cytoskeleton organisation + biological_process + regulation of actin cytoskeleton organization and biogenesis + GO:0032956 + regulation of actin cytoskeleton organization + + + + + Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins. + GOC:mah + + + + + regulation of actin cytoskeleton organisation + GOC:mah + + + + + regulation of actin cytoskeleton organization and biogenesis + GOC:mah + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways involving collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%). + collagen metabolism + biological_process + GO:0032963 + collagen metabolic process + + + + + The chemical reactions and pathways involving collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%). + GOC:mah + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%). + collagen anabolism + collagen biosynthesis + collagen formation + collagen synthesis + biological_process + GO:0032964 + collagen biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%). + GOC:mah + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. + regulation of collagen anabolism + regulation of collagen biosynthesis + regulation of collagen formation + regulation of collagen synthesis + biological_process + GO:0032965 + regulation of collagen biosynthetic process + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. + negative regulation of collagen anabolism + negative regulation of collagen biosynthesis + negative regulation of collagen formation + negative regulation of collagen synthesis + biological_process + GO:0032966 + negative regulation of collagen biosynthetic process + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. + positive regulation of collagen anabolism + positive regulation of collagen biosynthesis + positive regulation of collagen formation + positive regulation of collagen synthesis + biological_process + GO:0032967 + positive regulation of collagen biosynthetic process + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the actin cytoskeleton. + biological_process + GO:0032970 + regulation of actin filament-based process + + + + + Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the actin cytoskeleton. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A change in the morphology or behavior of a keratinocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. Upon activation, keratinocytes become migratory and hyperproliferative, and produce growth factors and cytokines. + + biological_process + GO:0032980 + keratinocyte activation + + + + + A change in the morphology or behavior of a keratinocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. Upon activation, keratinocytes become migratory and hyperproliferative, and produce growth factors and cytokines. + GOC:mah + PMID:15737202 + + + + + + + + + + + + + + + + + + + + + The process in which cellular structures, including whole cells or cell parts, are generated and organized. + cellular structure morphogenesis + biological_process + GO:0032989 + + cellular component morphogenesis + + + + + The process in which cellular structures, including whole cells or cell parts, are generated and organized. + GOC:dph + GOC:mah + GOC:tb + + + + + cellular structure morphogenesis + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of a cell part are generated and organized. + biological_process + GO:0032990 + cell part morphogenesis + + + + + The process in which the anatomical structures of a cell part are generated and organized. + GOC:mah + + + + + + + + + + + + + + + + A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. + GO:0043234 + macromolecular complex + macromolecule complex + protein containing complex + protein complex + protein-protein complex + cellular_component + GO:0032991 + + + + + + A protein complex in this context is meant as a stable set of interacting proteins which can be co-purified by an acceptable method, and where the complex has been shown to exist as an isolated, functional unit in vivo. Acceptable experimental methods include stringent protein purification followed by detection of protein interaction. The following methods should be considered non-acceptable: simple immunoprecipitation, pull-down experiments from cell extracts without further purification, colocalization and 2-hybrid screening. Interactions that should not be captured as protein complexes include: 1) enzyme/substrate, receptor/ligand or any similar transient interactions, unless these are a critical part of the complex assembly or are required e.g. for the receptor to be functional; 2) proteins associated in a pull-down/co-immunoprecipitation assay with no functional link or any evidence that this is a defined biological entity rather than a loose-affinity complex; 3) any complex where the only evidence is based on genetic interaction data; 4) partial complexes, where some subunits (e.g. transmembrane ones) cannot be expressed as recombinant proteins and are excluded from experiments (in this case, independent evidence is necessary to find out the composition of the full complex, if known). Interactions that may be captured as protein complexes include: 1) enzyme/substrate or receptor/ligand if the complex can only assemble and become functional in the presence of both classes of subunits; 2) complexes where one of the members has not been shown to be physically linked to the other(s), but is a homologue of, and has the same functionality as, a protein that has been experimentally demonstrated to form a complex with the other member(s); 3) complexes whose existence is accepted based on localization and pharmacological studies, but for which experimental evidence is not yet available for the complex as a whole. + protein-containing complex + + + + + A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together. + GOC:dos + GOC:mah + + + + + + + + + + + + + + + + + + + + The expansion of a muscle cell population by cell division. + myocyte proliferation + biological_process + GO:0033002 + muscle cell proliferation + + + + + The expansion of a muscle cell population by cell division. + CL:0000187 + GOC:mah + + + + + + + + + Any process in which a macromolecule is transported to, or maintained in, a specific location. + macromolecule localisation + biological_process + GO:0033036 + + macromolecule localization + + + + + Any process in which a macromolecule is transported to, or maintained in, a specific location. + GOC:mah + + + + + macromolecule localisation + GOC:mah + + + + + + + + + + + + + + + + + + + + Any process in which a polysaccharide is transported to, or maintained in, a specific location. + polysaccharide localisation + biological_process + GO:0033037 + polysaccharide localization + + + + + Any process in which a polysaccharide is transported to, or maintained in, a specific location. + GOC:mah + + + + + polysaccharide localisation + GOC:mah + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle. + regulation of organelle organisation + biological_process + regulation of organelle organization and biogenesis + GO:0033043 + + regulation of organelle organization + + + + + Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle. + GOC:mah + + + + + regulation of organelle organisation + GOC:mah + + + + + regulation of organelle organization and biogenesis + GOC:mah + + + + + + + + + + The deposition or aggregation of coloring matter in a cell. + biological_process + GO:0033059 + cellular pigmentation + + + + + The deposition or aggregation of coloring matter in a cell. + GOC:mtg_MIT_16mar07 + + + + + + + + + + + + + + + + + + + + The process in which a precursor cell type acquires the specialized features of a T cell via a differentiation pathway dependent upon transit through the thymus. + thymic T cell differentiation + thymocyte cell differentiation + thymocyte differentiation + biological_process + T cell development in thymus + GO:0033077 + Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. + T cell differentiation in thymus + + + + + The process in which a precursor cell type acquires the specialized features of a T cell via a differentiation pathway dependent upon transit through the thymus. + GOC:add + ISBN:0781735149 + + + + + T cell development in thymus + GOC:add + + + + + + + + + + + + + + + + + + + + The expansion of an immature T cell population by cell division. + biological_process + GO:0033079 + immature T cell proliferation + + + + + The expansion of an immature T cell population by cell division. + GOC:add + ISBN:0781735149 + + + + + + + + + + + + + + + + + + + + + + + + + + The expansion of an immature T cell population by cell division in the thymus. + thymic T cell proliferation + thymocyte cell proliferation + thymocyte proliferation + biological_process + GO:0033080 + immature T cell proliferation in thymus + + + + + The expansion of an immature T cell population by cell division in the thymus. + GOC:add + ISBN:0781735149 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of T cell differentiation in the thymus. + regulation of thymic T cell differentiation + regulation of thymocyte cell differentiation + regulation of thymocyte differentiation + biological_process + regulation of T cell development in thymus + GO:0033081 + Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. + regulation of T cell differentiation in thymus + + + + + Any process that modulates the frequency, rate or extent of T cell differentiation in the thymus. + GOC:add + GOC:mah + + + + + regulation of T cell development in thymus + GOC:add + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of immature T cell proliferation. + biological_process + GO:0033083 + regulation of immature T cell proliferation + + + + + Any process that modulates the frequency, rate or extent of immature T cell proliferation. + GOC:add + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of immature T cell proliferation in the thymus. + regulation of thymic T cell proliferation + regulation of thymocyte cell proliferation + regulation of thymocyte proliferation + biological_process + GO:0033084 + Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. + regulation of immature T cell proliferation in thymus + + + + + Any process that modulates the frequency, rate or extent of immature T cell proliferation in the thymus. + GOC:add + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation in the thymus. + negative regulation of thymic T cell differentiation + negative regulation of thymocyte cell differentiation + negative regulation of thymocyte differentiation + biological_process + negative regulation of T cell development in thymus + GO:0033085 + Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. + negative regulation of T cell differentiation in thymus + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation in the thymus. + GOC:add + GOC:mah + + + + + negative regulation of T cell development in thymus + GOC:add + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of immature T cell proliferation. + biological_process + GO:0033087 + negative regulation of immature T cell proliferation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of immature T cell proliferation. + GOC:add + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of immature T cell proliferation in the thymus. + negative regulation of thymic T cell proliferation + negative regulation of thymocyte cell proliferation + negative regulation of thymocyte proliferation + biological_process + GO:0033088 + negative regulation of immature T cell proliferation in thymus + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of immature T cell proliferation in the thymus. + GOC:add + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of T cell differentiation in the thymus. + positive regulation of thymic T cell differentiation + positive regulation of thymocyte cell differentiation + positive regulation of thymocyte differentiation + biological_process + positive regulation of T cell development in thymus + GO:0033089 + Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. + positive regulation of T cell differentiation in thymus + + + + + Any process that activates or increases the frequency, rate or extent of T cell differentiation in the thymus. + GOC:add + GOC:mah + + + + + positive regulation of T cell development in thymus + GOC:add + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of immature T cell proliferation. + biological_process + GO:0033091 + positive regulation of immature T cell proliferation + + + + + Any process that activates or increases the frequency, rate or extent of immature T cell proliferation. + GOC:add + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of immature T cell proliferation in the thymus. + positive regulation of thymic T cell proliferation + positive regulation of thymocyte cell proliferation + positive regulation of thymocyte proliferation + biological_process + GO:0033092 + positive regulation of immature T cell proliferation in thymus + + + + + Any process that activates or increases the frequency, rate or extent of immature T cell proliferation in the thymus. + GOC:add + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway. + regulation of steroid hormone receptor signaling pathway + regulation of steroid hormone receptor signalling pathway + biological_process + GO:0033143 + regulation of intracellular steroid hormone receptor signaling pathway + + + + + Any process that modulates the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway. + GOC:mah + + + + + regulation of steroid hormone receptor signaling pathway + GOC:bf + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway. + negative regulation of steroid hormone receptor signaling pathway + negative regulation of steroid hormone receptor signalling pathway + biological_process + GO:0033144 + negative regulation of intracellular steroid hormone receptor signaling pathway + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway. + GOC:mah + + + + + negative regulation of steroid hormone receptor signaling pathway + GOC:bf + + + + + negative regulation of steroid hormone receptor signalling pathway + GOC:bf + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway. + positive regulation of steroid hormone receptor signaling pathway + positive regulation of steroid hormone receptor signalling pathway + biological_process + GO:0033145 + positive regulation of intracellular steroid hormone receptor signaling pathway + + + + + Any process that activates or increases the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway. + GOC:mah + + + + + positive regulation of steroid hormone receptor signaling pathway + GOC:bf + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the directed movement of proteins within cells. + biological_process + GO:0033157 + regulation of intracellular protein transport + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate or extent of the directed movement of proteins within cells. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + + + The directed movement of iron ions from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis. + mah + 2009-05-01T04:19:14Z + GO:0070627 + ferrous ion import + ferrous iron import + ferrous iron uptake + biological_process + iron assimilation + GO:0033212 + iron import into cell + + + + + The directed movement of iron ions from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis. + PMID:18622392 + PMID:23192658 + Wikipedia:Human_iron_metabolism + + + + + + + + + + + + + + + + + + + Binding to an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group. + molecular_function + GO:0033218 + + amide binding + + + + + Binding to an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group. + GOC:mah + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform amines. + regulation of amine metabolism + biological_process + GO:0033238 + regulation of cellular amine metabolic process + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform amines. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amines. + negative regulation of amine metabolism + biological_process + GO:0033239 + negative regulation of cellular amine metabolic process + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amines. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amines. + positive regulation of amine metabolism + biological_process + GO:0033240 + positive regulation of cellular amine metabolic process + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amines. + GOC:mah + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines. + regulation of amine breakdown + regulation of amine catabolism + regulation of amine degradation + biological_process + GO:0033241 + regulation of cellular amine catabolic process + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines. + GOC:mah + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines. + negative regulation of amine breakdown + negative regulation of amine catabolism + negative regulation of amine degradation + biological_process + GO:0033242 + negative regulation of cellular amine catabolic process + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines. + GOC:mah + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines. + positive regulation of amine breakdown + positive regulation of amine catabolism + positive regulation of amine degradation + biological_process + GO:0033243 + positive regulation of cellular amine catabolic process + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines. + GOC:mah + + + + + + + + + + + + + + + + + + + Binding to choline, the amine 2-hydroxy-N,N,N-trimethylethanaminium. + molecular_function + GO:0033265 + choline binding + + + + + Binding to choline, the amine 2-hydroxy-N,N,N-trimethylethanaminium. + GOC:mlg + + + + + + + + + + + + + + + + + + + + + + + + + + The multiplication or reproduction of cells, resulting in the expansion of a cell population in the midbrain. + cell proliferation in mesencephalon + biological_process + mesencepahalic cell proliferation + GO:0033278 + cell proliferation in midbrain + + + + + The multiplication or reproduction of cells, resulting in the expansion of a cell population in the midbrain. + GOC:dgf + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + Binding to a monocarboxylic acid, any organic acid containing one carboxyl (COOH) group or anion (COO-). + molecular_function + GO:0033293 + monocarboxylic acid binding + + + + + Binding to a monocarboxylic acid, any organic acid containing one carboxyl (COOH) group or anion (COO-). + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Leydig cell. A Leydig cell is a testosterone-secreting cell in the interstitial area, between the seminiferous tubules, in the testis. + biological_process + GO:0033327 + Leydig cell differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Leydig cell. A Leydig cell is a testosterone-secreting cell in the interstitial area, between the seminiferous tubules, in the testis. + GOC:ln + PMID:12050120 + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a fin over time, from its formation to the mature structure. + biological_process + GO:0033333 + fin development + + + + + The process whose specific outcome is the progression of a fin over time, from its formation to the mature structure. + GOC:dgh + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of a fin are generated and organized. + biological_process + GO:0033334 + fin morphogenesis + + + + + The process in which the anatomical structures of a fin are generated and organized. + GOC:dgh + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the anal fin over time, from its formation to the mature structure. + biological_process + GO:0033335 + anal fin development + + + + + The process whose specific outcome is the progression of the anal fin over time, from its formation to the mature structure. + GOC:dgh + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the caudal fin over time, from its formation to the mature structure. + biological_process + GO:0033336 + caudal fin development + + + + + The process whose specific outcome is the progression of the caudal fin over time, from its formation to the mature structure. + GOC:dgh + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the dorsal fin over time, from its formation to the mature structure. + biological_process + GO:0033337 + dorsal fin development + + + + + The process whose specific outcome is the progression of the dorsal fin over time, from its formation to the mature structure. + GOC:dgh + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a medial fin over time, from its formation to the mature structure. + median fin development + biological_process + GO:0033338 + medial fin development + + + + + The process whose specific outcome is the progression of a medial fin over time, from its formation to the mature structure. + GOC:dgh + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the pectoral fin over time, from its formation to the mature structure. + biological_process + GO:0033339 + pectoral fin development + + + + + The process whose specific outcome is the progression of the pectoral fin over time, from its formation to the mature structure. + GOC:dgh + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the pelvic fin over time, from its formation to the mature structure. + biological_process + GO:0033340 + pelvic fin development + + + + + The process whose specific outcome is the progression of the pelvic fin over time, from its formation to the mature structure. + GOC:dgh + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of collagen binding. + biological_process + GO:0033341 + regulation of collagen binding + + + + + Any process that modulates the frequency, rate or extent of collagen binding. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of collagen binding. + down regulation of collagen binding + down-regulation of collagen binding + downregulation of collagen binding + inhibition of collagen binding + biological_process + GO:0033342 + negative regulation of collagen binding + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of collagen binding. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of collagen binding. + up regulation of collagen binding + up-regulation of collagen binding + upregulation of collagen binding + activation of collagen binding + stimulation of collagen binding + biological_process + GO:0033343 + positive regulation of collagen binding + + + + + Any process that activates or increases the frequency, rate or extent of collagen binding. + GOC:mah + + + + + + + + + + + + + + + + + + + + A process in which a protein is transported to, or maintained in, a location within an organelle. + protein localisation to organelle + protein localization in organelle + biological_process + GO:0033365 + protein localization to organelle + + + + + A process in which a protein is transported to, or maintained in, a location within an organelle. + GOC:mah + + + + + protein localisation to organelle + GOC:mah + + + + + protein localization in organelle + GOC:mah + + + + + + + + + + + + + + + + + + + A homeostatic process involved in the maintenance of an internal steady state of a carbohydrate within an organism or cell. + biological_process + GO:0033500 + carbohydrate homeostasis + + + + + A homeostatic process involved in the maintenance of an internal steady state of a carbohydrate within an organism or cell. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the floor plate over time from its initial formation until its mature state. + biological_process + GO:0033504 + floor plate development + + + + + The progression of the floor plate over time from its initial formation until its mature state. + GOC:dh + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of the floor plate is generated and organized. + biological_process + GO:0033505 + floor plate morphogenesis + + + + + The process in which the anatomical structure of the floor plate is generated and organized. + GOC:dh + + + + + + + + + + + + + + + + + + + + + The directed movement of lactoferrin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + biological_process + GO:0033571 + lactoferrin transport + + + + + The directed movement of lactoferrin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:mlg + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of dopamine. + down regulation of dopamine secretion + down-regulation of dopamine secretion + downregulation of dopamine secretion + inhibition of dopamine secretion + biological_process + GO:0033602 + negative regulation of dopamine secretion + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of dopamine. + GOC:sl + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the regulated release of dopamine. + up regulation of dopamine secretion + up-regulation of dopamine secretion + upregulation of dopamine secretion + activation of dopamine secretion + stimulation of dopamine secretion + biological_process + GO:0033603 + positive regulation of dopamine secretion + + + + + Any process that activates or increases the frequency, rate or extent of the regulated release of dopamine. + GOC:sl + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a catecholamine. + down regulation of catecholamine secretion + down-regulation of catecholamine secretion + downregulation of catecholamine secretion + inhibition of catecholamine secretion + biological_process + GO:0033604 + negative regulation of catecholamine secretion + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a catecholamine. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the regulated release of a catecholamine. + up regulation of catecholamine secretion + up-regulation of catecholamine secretion + upregulation of catecholamine secretion + activation of catecholamine secretion + stimulation of catecholamine secretion + biological_process + GO:0033605 + positive regulation of catecholamine secretion + + + + + Any process that activates or increases the frequency, rate or extent of the regulated release of a catecholamine. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. + down regulation of kinase activity + down-regulation of kinase activity + downregulation of kinase activity + inhibition of kinase activity + kinase inhibitor + biological_process + GO:0033673 + negative regulation of kinase activity + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. + up regulation of kinase activity + up-regulation of kinase activity + upregulation of kinase activity + kinase activator + stimulation of kinase activity + biological_process + GO:0033674 + positive regulation of kinase activity + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. + GOC:mah + + + + + + + + + + + + + + + + + + + + The multiplication or reproduction of osteoblasts, resulting in the expansion of an osteoblast cell population. An osteoblast is a bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone. + biological_process + GO:0033687 + osteoblast proliferation + + + + + The multiplication or reproduction of osteoblasts, resulting in the expansion of an osteoblast cell population. An osteoblast is a bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of osteoblast proliferation. + biological_process + GO:0033688 + regulation of osteoblast proliferation + + + + + Any process that modulates the frequency, rate or extent of osteoblast proliferation. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the rate or extent of osteoblast proliferation. + down regulation of osteoblast proliferation + down-regulation of osteoblast proliferation + downregulation of osteoblast proliferation + inhibition of osteoblast proliferation + biological_process + GO:0033689 + negative regulation of osteoblast proliferation + + + + + Any process that stops, prevents or reduces the rate or extent of osteoblast proliferation. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that activates or increases the rate or extent of osteoblast proliferation. + up regulation of osteoblast proliferation + up-regulation of osteoblast proliferation + upregulation of osteoblast proliferation + activation of osteoblast proliferation + stimulation of osteoblast proliferation + biological_process + GO:0033690 + positive regulation of osteoblast proliferation + + + + + Any process that activates or increases the rate or extent of osteoblast proliferation. + GOC:mah + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of polysaccharides, polymers of many (typically more than 10) monosaccharide residues linked glycosidically, occurring at the level of an individual cell. + cellular glycan biosynthesis + cellular glycan biosynthetic process + cellular polysaccharide anabolism + cellular polysaccharide biosynthesis + cellular polysaccharide formation + cellular polysaccharide synthesis + biological_process + GO:0033692 + cellular polysaccharide biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of polysaccharides, polymers of many (typically more than 10) monosaccharide residues linked glycosidically, occurring at the level of an individual cell. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus. + response to glucagon stimulus + biological_process + GO:0033762 + response to glucagon + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus. + GOC:sl + + + + + response to glucagon stimulus + GOC:dos + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus. + biological_process + GO:0033993 + response to lipid + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus. + GOC:sl + + + + + + + + + + + + + + + + + + + A process in which a protein is transported to, or maintained in, a location within the Golgi apparatus. + mah + 2011-02-14T02:26:36Z + GO:0000042 + GO:0072600 + protein localisation in Golgi apparatus + protein localization in Golgi apparatus + establishment of protein localisation to Golgi + establishment of protein localization in Golgi + establishment of protein localization to Golgi + establishment of protein localization to Golgi apparatus + biological_process + protein targeting to Golgi + protein-Golgi targeting + GO:0034067 + protein localization to Golgi apparatus + + + + + A process in which a protein is transported to, or maintained in, a location within the Golgi apparatus. + GOC:mah + + + + + protein localisation in Golgi apparatus + GOC:mah + + + + + establishment of protein localisation to Golgi + GOC:mah + + + + + establishment of protein localization to Golgi apparatus + GOC:mah + + + + + + + + + + + + + + + + + + + Any process of regulating the production and elimination of erythrocytes within an organism. + RBC homeostasis + red blood cell homeostasis + biological_process + GO:0034101 + erythrocyte homeostasis + + + + + Any process of regulating the production and elimination of erythrocytes within an organism. + GOC:add + PMID:10694114 + PMID:14754397 + + + + + RBC homeostasis + CL:0000232 + + + + + red blood cell homeostasis + CL:0000232 + + + + + + + + + + + + + + + + + + + + Any process that decreases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells. + biological_process + GO:0034242 + negative regulation of syncytium formation by plasma membrane fusion + + + + + Any process that decreases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells. + GOC:mah + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amides. + regulation of amide metabolism + biological_process + GO:0034248 + regulation of cellular amide metabolic process + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amides. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amides. + negative regulation of amide metabolism + biological_process + GO:0034249 + negative regulation of cellular amide metabolic process + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amides. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amides. + positive regulation of amide metabolism + biological_process + GO:0034250 + positive regulation of cellular amide metabolic process + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amides. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus. + response to monosaccharide stimulus + biological_process + GO:0034284 + response to monosaccharide + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus. + GOC:mah + + + + + response to monosaccharide stimulus + GOC:dos + + + + + + + + + + + + + + + + + + + A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a cell junction. + biological_process + GO:0034329 + cell junction assembly + + + + + A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a cell junction. + GOC:mah + + + + + + + + + + + + + + + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell junction. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix. + cell junction assembly and maintenance + cell junction organisation + biological_process + cell junction biogenesis + GO:0034330 + + + cell junction organization + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell junction. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix. + GOC:dph + GOC:jl + GOC:mah + + + + + cell junction organisation + GOC:mah + + + + + + + + + + + + + + + + + + + + Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the optic tectum towards target cells in the premotor reticulospinal system in the hindbrain. + biological_process + GO:0034429 + tectobulbar tract morphogenesis + + + + + Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the optic tectum towards target cells in the premotor reticulospinal system in the hindbrain. + GOC:dsf + PMID:15065115 + PMID:17507550 + PMID:8038988 + + + + + + + + + + + + + + + + + + + The directed movement of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + biological_process + GO:0034436 + glycoprotein transport + + + + + The directed movement of a glycoprotein, a protein that contains covalently bound glycose (i.e. monosaccharide) residues, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:BHF + GOC:mah + GOC:rl + + + + + + + + + + + + + + + + + + + A process in which a protein transports or maintains the localization of another protein to the nucleus. + 2012-11-07T15:45:54Z + GO:0044744 + protein localisation to nucleus + protein localization in cell nucleus + protein localization in nucleus + biological_process + protein targeting to nucleus + GO:0034504 + protein localization to nucleus + + + + + A process in which a protein transports or maintains the localization of another protein to the nucleus. + GOC:ecd + + + + + protein localisation to nucleus + GOC:mah + + + + + protein localization in nucleus + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which calcium salts are deposited into calcareous tooth structures such as dental enamel, dentin and cementum. + tooth calcification + biological_process + GO:0034505 + tooth mineralization + + + + + The process in which calcium salts are deposited into calcareous tooth structures such as dental enamel, dentin and cementum. + GOC:mah + MP:0002817 + MSH:D014074 + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, carried out by individual cells. + biological_process + GO:0034637 + cellular carbohydrate biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, carried out by individual cells. + GOC:mah + + + + + + + + + + The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells. + cellular nitrogen compound metabolism + biological_process + GO:0034641 + + cellular nitrogen compound metabolic process + + + + + The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells. + GOC:mah + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells. + GO:0034961 + cellular biopolymer biosynthetic process + cellular macromolecule anabolism + cellular macromolecule biosynthesis + cellular macromolecule formation + cellular macromolecule synthesis + biological_process + GO:0034645 + cellular macromolecule biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells. + GOC:mah + + + + + cellular biopolymer biosynthetic process + GOC:mtg_chebi_dec09 + + + + + cellular macromolecule anabolism + GOC:mah + + + + + cellular macromolecule biosynthesis + GOC:mah + + + + + cellular macromolecule formation + GOC:mah + + + + + cellular macromolecule synthesis + GOC:mah + + + + + + + + + + + + + + + + + + + The developmental process that results in the creation of defined areas or spaces within the pronephros along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate. + anterior/posterior pattern specification involved in pronephric kidney development + biological_process + GO:0034672 + anterior/posterior pattern specification involved in pronephros development + + + + + The developmental process that results in the creation of defined areas or spaces within the pronephros along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate. + GOC:mah + + + + + anterior/posterior pattern specification involved in pronephric kidney development + GOC:mtg_kidney_jan10 + + + + + + + + + + The chemical reactions and pathways involving any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone, as carried out by individual cells. + biological_process + GO:0034754 + cellular hormone metabolic process + + + + + The chemical reactions and pathways involving any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone, as carried out by individual cells. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + mah + 2012-04-18T04:00:14Z + GO:1900390 + regulation of Fe transport + regulation of iron transport + regulation of iron import + regulation of iron ion import + biological_process + GO:0034756 + regulation of iron ion transport + + + + + Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:mah + + + + + regulation of iron import + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of iron ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + down regulation of iron ion transport + down-regulation of iron ion transport + downregulation of iron ion transport + negative regulation of iron transport + inhibition of iron ion transport + biological_process + GO:0034757 + negative regulation of iron ion transport + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of iron ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the directed movement of iron ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + positive regulation of iron transport + up regulation of iron ion transport + up-regulation of iron ion transport + upregulation of iron ion transport + activation of iron ion transport + stimulation of iron ion transport + biological_process + GO:0034758 + positive regulation of iron ion transport + + + + + Any process that activates or increases the frequency, rate or extent of the directed movement of iron ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter. + response to histamine stimulus + biological_process + GO:0034776 + response to histamine + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter. + GOC:BHF + GOC:mah + GOC:vk + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the embryonic heart tube over time, from its formation to the mature structure. The heart tube forms as the heart rudiment from the heart field. + biological_process + GO:0035050 + embryonic heart tube development + + + + + The process whose specific outcome is the progression of the embryonic heart tube over time, from its formation to the mature structure. The heart tube forms as the heart rudiment from the heart field. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell that will form part of the cardiac organ of an individual. + cardiac cell differentiation + heart cell differentiation + biological_process + GO:0035051 + cardiocyte differentiation + + + + + The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell that will form part of the cardiac organ of an individual. + GOC:bf + + + + + + + + + + + + + + + + + + + + + + + + + + The assembly and organization of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements. + GO:0035083 + GO:0035084 + ciliary axoneme assembly + cilium axoneme assembly + flagellar axoneme assembly + flagellum axoneme assembly + biological_process + axoneme biogenesis + cilium axoneme biogenesis + GO:0035082 + Note that cilia and eukaryotic flagella are deemed to be equivalent. + axoneme assembly + + + + + The assembly and organization of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements. + GOC:bf + GOC:cilia + GOC:jl + ISBN:0815316194 + + + + + axoneme biogenesis + GOC:mah + + + + + cilium axoneme biogenesis + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The directed movement of a hemocyte within the embryo. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. In Drosophila, embryonic hemocytes originate from the head mesoderm as a cluster of cells. The cluster splits into two and one group of cells crosses the amnioserosa. Both populations then spread toward the middle of the embryo and then disperse evenly throughout the embryo. + arthropod blood cell migration + hemocyte cell migration + biological_process + GO:0035099 + hemocyte migration + + + + + The directed movement of a hemocyte within the embryo. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. In Drosophila, embryonic hemocytes originate from the head mesoderm as a cluster of cells. The cluster splits into two and one group of cells crosses the amnioserosa. Both populations then spread toward the middle of the embryo and then disperse evenly throughout the embryo. + GOC:bf + GOC:mtg_sensu + PMID:12885551 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch. + biological_process + GO:0035107 + appendage morphogenesis + + + + + The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch. + ISBN:0582227089 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of a limb are generated and organized. A limb is a paired appendage of a tetrapod used for locomotion or grasping. + limb bud morphogenesis + biological_process + GO:0035108 + limb morphogenesis + + + + + The process in which the anatomical structures of a limb are generated and organized. A limb is a paired appendage of a tetrapod used for locomotion or grasping. + UBERON:0002101 + + + + + limb bud morphogenesis + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of genitalia are generated and organized. The genitalia are the organs of reproduction or generation, external and internal. + biological_process + genital morphogenesis + GO:0035112 + genitalia morphogenesis + + + + + The process in which the anatomical structures of genitalia are generated and organized. The genitalia are the organs of reproduction or generation, external and internal. + GOC:bf + + + + + + + + + + + + + + + The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism. + biological_process + GO:0035114 + imaginal disc-derived appendage morphogenesis + + + + + The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism. + GOC:mtg_sensu + ISBN:0582227089 + + + + + + + + + + The process, occurring after embryonic development, by which the anatomical structures of an appendage are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch. + biological_process + GO:0035120 + post-embryonic appendage morphogenesis + + + + + The process, occurring after embryonic development, by which the anatomical structures of an appendage are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch. + ISBN:0582227089 + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human. + GO:0035140 + arm morphogenesis + biological_process + GO:0035136 + forelimb morphogenesis + + + + + The process in which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human. + GOC:go_curators + + + + + arm morphogenesis + GOC:bf + GOC:cjm + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the hindlimb are generated and organized. + biological_process + GO:0035137 + hindlimb morphogenesis + + + + + The process in which the anatomical structures of the hindlimb are generated and organized. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion. + biological_process + GO:0035138 + pectoral fin morphogenesis + + + + + The process in which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion. + GOC:dgh + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the pelvic fin are generated and organized. Pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion. + biological_process + GO:0035139 + pelvic fin morphogenesis + + + + + The process in which the anatomical structures of the pelvic fin are generated and organized. Pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion. + GOC:dgh + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the medial fin are generated and organized. A medial fin is an unpaired fin of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming. + median fin morphogenesis + unpaired fin morphogenesis + biological_process + GO:0035141 + medial fin morphogenesis + + + + + The process in which the anatomical structures of the medial fin are generated and organized. A medial fin is an unpaired fin of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming. + GOC:dgh + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins. + biological_process + GO:0035142 + dorsal fin morphogenesis + + + + + The process in which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins. + GOC:dgh + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the caudal fin are generated and organized. A caudal fin is an unpaired medial fin mounted at the caudal end of the fish, and is the main fin used for propulsion. + biological_process + GO:0035143 + caudal fin morphogenesis + + + + + The process in which the anatomical structures of the caudal fin are generated and organized. A caudal fin is an unpaired medial fin mounted at the caudal end of the fish, and is the main fin used for propulsion. + GOC:dgh + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming. + biological_process + GO:0035144 + anal fin morphogenesis + + + + + The process in which the anatomical structures of the anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming. + GOC:dgh + + + + + + + + + + + + + + + + + + + + + + + + + + + Creation of the central hole of a tube in an anatomical structure through which gases and/or liquids flow. + tube lumen formation + biological_process + lumen formation in an anatomical structure + GO:0035148 + tube formation + + + + + Creation of the central hole of a tube in an anatomical structure through which gases and/or liquids flow. + GOC:bf + + + + + tube lumen formation + GOC:dph + GOC:mah + + + + + lumen formation in an anatomical structure + GOC:dph + GOC:mah + + + + + + + + + + The stages of blood cell formation that take place within the embryo. + embryonic haematopoiesis + embryonic haemopoiesis + embryonic hematopoiesis + biological_process + GO:0035162 + embryonic hemopoiesis + + + + + The stages of blood cell formation that take place within the embryo. + GOC:bf + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The multiplication or reproduction of hemocytes, resulting in the expansion of the cell population. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. + arthropod blood cell proliferation + biological_process + GO:0035172 + hemocyte proliferation + + + + + The multiplication or reproduction of hemocytes, resulting in the expansion of the cell population. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. + GOC:bf + GOC:mtg_sensu + + + + + + + + + + + + + + + The emergence of an immature organism from a protective structure. + biological_process + GO:0035188 + hatching + + + + + The emergence of an immature organism from a protective structure. + GOC:dgh + GOC:isa_complete + ISBN:0198612001 + + + + + + + + + + + + + + + + + + + + + + + + + + The directed movement of nuclei within the syncytial embryo of insects. These precise temporal and spatial patterns of nuclear movement are coordinated with mitotic divisons and are required during blastoderm formation to reposition dividing nuclei from the interior of the syncytial embryo to the cortex. + biological_process + GO:0035190 + syncytial nuclear migration + + + + + The directed movement of nuclei within the syncytial embryo of insects. These precise temporal and spatial patterns of nuclear movement are coordinated with mitotic divisons and are required during blastoderm formation to reposition dividing nuclei from the interior of the syncytial embryo to the cortex. + GOC:bf + ISBN:0879694238 + PMID:8314839 + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster. + regulation of arthropod blood cell proliferation + biological_process + GO:0035206 + regulation of hemocyte proliferation + + + + + Any process that modulates the frequency, rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster. + GOC:bf + GOC:mtg_sensu + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster. + down regulation of hemocyte proliferation + down-regulation of hemocyte proliferation + downregulation of hemocyte proliferation + negative regulation of arthropod blood cell proliferation + inhibition of hemocyte proliferation + biological_process + GO:0035207 + negative regulation of hemocyte proliferation + + + + + Any process that stops, prevents or reduces the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster. + GOC:bf + GOC:mtg_sensu + + + + + + + + + + + + + + + + + + + Any process that activates or increases the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) that are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this process is found in Drosophila melanogaster. + positive regulation of arthropod blood cell proliferation + up regulation of hemocyte proliferation + up-regulation of hemocyte proliferation + upregulation of hemocyte proliferation + activation of hemocyte proliferation + stimulation of hemocyte proliferation + biological_process + GO:0035208 + positive regulation of hemocyte proliferation + + + + + Any process that activates or increases the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) that are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this process is found in Drosophila melanogaster. + GOC:bf + GOC:mtg_sensu + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the pupa over time, from its formation to the mature structure. The pupa is a dormant life stage interposed between the larval and the adult stages in insects that undergo a complete metamorphosis. + biological_process + GO:0035209 + pupal development + + + + + The process whose specific outcome is the progression of the pupa over time, from its formation to the mature structure. The pupa is a dormant life stage interposed between the larval and the adult stages in insects that undergo a complete metamorphosis. + GOC:bf + GOC:mtg_sensu + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of a spermathecum, a sperm storage organ, are generated and organized. Paired spermathecae lie at the anterior end of the insect uterus on the dorsal side. Each spermatheca consists of an oval shaped capsule, connected to the uterus by a spermathecal stalk. + biological_process + GO:0035211 + See also the fly_anatomy.ontology term 'spermathecum ; FBbt:00004921'. + spermathecum morphogenesis + + + + + The process in which the anatomical structures of a spermathecum, a sperm storage organ, are generated and organized. Paired spermathecae lie at the anterior end of the insect uterus on the dorsal side. Each spermatheca consists of an oval shaped capsule, connected to the uterus by a spermathecal stalk. + PMID:12679097 + + + + + + + + + Progression of the eye-antennal imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including the eye, antenna, head capsule and maxillary palps. + biological_process + GO:0035214 + eye-antennal disc development + + + + + Progression of the eye-antennal imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including the eye, antenna, head capsule and maxillary palps. + GOC:bf + ISBN:0879694238 + + + + + + + + + Progression of the haltere imaginal disc over time, from its initial formation through to its metamorphosis to form the adult capitellum, pedicel, haltere sclerite, metathoracic spiracle and metanotum. + biological_process + GO:0035216 + haltere disc development + + + + + Progression of the haltere imaginal disc over time, from its initial formation through to its metamorphosis to form the adult capitellum, pedicel, haltere sclerite, metathoracic spiracle and metanotum. + GOC:bf + ISBN:0879694238 + + + + + + + + + Progression of the leg imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including the leg, coxa and ventral thoracic pleura. + biological_process + GO:0035218 + leg disc development + + + + + Progression of the leg imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including the leg, coxa and ventral thoracic pleura. + GOC:bf + ISBN:0879694238 + + + + + + + + + Progression of the wing disc over time, from its initial formation through to its metamorphosis to form adult structures including the wing hinge, wing blade and pleura. + biological_process + GO:0035220 + wing disc development + + + + + Progression of the wing disc over time, from its initial formation through to its metamorphosis to form adult structures including the wing hinge, wing blade and pleura. + GOC:bf + ISBN:0879694238 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of a tube are generated and organized. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system. + biological_process + GO:0035239 + tube morphogenesis + + + + + The process in which the anatomical structures of a tube are generated and organized. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system. + GOC:bf + PMID:14624839 + + + + + + + + + + + + + + + + + + + Binding to dopamine, a catecholamine neurotransmitter formed by aromatic-L-amino-acid decarboxylase from 3,4-dihydroxy-L-phenylalanine. + molecular_function + GO:0035240 + dopamine binding + + + + + Binding to dopamine, a catecholamine neurotransmitter formed by aromatic-L-amino-acid decarboxylase from 3,4-dihydroxy-L-phenylalanine. + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the internal genitalia are generated and organized. The internal genitalia are the internal sex organs such as the uterine tube, the uterus and the vagina in female mammals, and the testis, seminal vesicle, ejaculatory duct and prostate in male mammals. + biological_process + GO:0035260 + internal genitalia morphogenesis + + + + + The process in which the anatomical structures of the internal genitalia are generated and organized. The internal genitalia are the internal sex organs such as the uterine tube, the uterus and the vagina in female mammals, and the testis, seminal vesicle, ejaculatory duct and prostate in male mammals. + http://www.ndif.org/Terms/genitalia.html + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the external genitalia are generated and organized. The external genitalia are the outer sex organs, such as the penis or vulva in mammals. + biological_process + GO:0035261 + external genitalia morphogenesis + + + + + The process in which the anatomical structures of the external genitalia are generated and organized. The external genitalia are the outer sex organs, such as the penis or vulva in mammals. + http://www.ndif.org/Terms/genitalia.html + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the gonads are generated and organized. A gonad is an animal organ producing gametes, e.g. the testes or the ovary in mammals. + biological_process + GO:0035262 + gonad morphogenesis + + + + + The process in which the anatomical structures of the gonads are generated and organized. A gonad is an animal organ producing gametes, e.g. the testes or the ovary in mammals. + ISBN:0198612001 + + + + + + + + + + + + + + + + + + + + + The increase in size or mass of an entire multicellular organism, as opposed to cell growth. + biological_process + body growth + GO:0035264 + multicellular organism growth + + + + + The increase in size or mass of an entire multicellular organism, as opposed to cell growth. + GOC:bf + GOC:curators + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + The increase in size or mass of an organ. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that function together as to perform a specific function. + biological_process + GO:0035265 + organ growth + + + + + The increase in size or mass of an organ. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that function together as to perform a specific function. + GOC:bf + ISBN:0471245208 + ISBN:0721662544 + + + + + + + + + + + + + + + + + + + + Progression of the endocrine system over time, from its formation to a mature structure. The endocrine system is a system of hormones and ductless glands, where the glands release hormones directly into the blood, lymph or other intercellular fluid, and the hormones circulate within the body to affect distant organs. The major glands that make up the human endocrine system are the hypothalamus, pituitary, thyroid, parathryoids, adrenals, pineal body, and the reproductive glands which include the ovaries and testes. + biological_process + GO:0035270 + endocrine system development + + + + + Progression of the endocrine system over time, from its formation to a mature structure. The endocrine system is a system of hormones and ductless glands, where the glands release hormones directly into the blood, lymph or other intercellular fluid, and the hormones circulate within the body to affect distant organs. The major glands that make up the human endocrine system are the hypothalamus, pituitary, thyroid, parathryoids, adrenals, pineal body, and the reproductive glands which include the ovaries and testes. + GOC:bf + Wikipedia:Development_of_the_endocrine_system + + + + + + + + + + + + + + + + + + + + Progression of the exocrine system over time, from its formation to a mature structure. The exocrine system is a system of hormones and glands, where the glands secrete straight to a target site via ducts or tubes. The human exocrine system includes the salivary glands, sweat glands and many glands of the digestive system. + biological_process + GO:0035272 + exocrine system development + + + + + Progression of the exocrine system over time, from its formation to a mature structure. The exocrine system is a system of hormones and glands, where the glands secrete straight to a target site via ducts or tubes. The human exocrine system includes the salivary glands, sweat glands and many glands of the digestive system. + GOC:bf + Wikipedia:Exocrine_gland + + + + + + + + + The regionalization process that divides an organism or part of an organism into a series of semi-repetitive parts, or segments, often arranged along a longitudinal axis. + Wikipedia:Segmentation_(biology) + biological_process + GO:0035282 + segmentation + + + + + The regionalization process that divides an organism or part of an organism into a series of semi-repetitive parts, or segments, often arranged along a longitudinal axis. + PMID:10611687 + PMID:9706689 + + + + + + + + + + + + + + + Partitioning of the blastoderm embryo into trunk segmental units. In Drosophila, the trunk segments include thoracic segments and abdominal segments A1 to A8. + biological_process + GO:0035290 + trunk segmentation + + + + + Partitioning of the blastoderm embryo into trunk segmental units. In Drosophila, the trunk segments include thoracic segments and abdominal segments A1 to A8. + PMID:1360402 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a tube over time, from its initial formation to a mature structure. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues including lung and trachea, kidney, the mammary gland, the vascular system and the gastrointestinal and urinary-genital tracts. + biological_process + GO:0035295 + tube development + + + + + The process whose specific outcome is the progression of a tube over time, from its initial formation to a mature structure. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues including lung and trachea, kidney, the mammary gland, the vascular system and the gastrointestinal and urinary-genital tracts. + PMID:12526790 + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of a hair cell. + biological_process + GO:0035315 + hair cell differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized features of a hair cell. + GOC:bf + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of non-sensory hairs. These hairs are polarized cellular extensions that cover much of the insect epidermis. + trichome organisation + trichome organization and biogenesis + biological_process + non-sensory hair organization and biogenesis + GO:0035316 + See also the fly_anatomy.ontology term 'trichome ; FBbt:00004979'. + non-sensory hair organization + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of non-sensory hairs. These hairs are polarized cellular extensions that cover much of the insect epidermis. + GOC:mtg_sensu + PMID:11064425 + + + + + non-sensory hair organization and biogenesis + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of an imaginal disc-derived wing hair. A wing hair is an actin-rich, polarized, non-sensory apical projection that protrudes from each of the approximately 30,000 wing epithelial cells. An example of this is found in Drosophila melanogaster. + wing hair organisation + wing trichome organization and biogenesis + biological_process + imaginal disc-derived wing hair organization and biogenesis + wing hair organization and biogenesis + GO:0035317 + See also the fly_anatomy.ontology term 'wing hair ; FBbt:00004340'. + imaginal disc-derived wing hair organization + + + + + A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of an imaginal disc-derived wing hair. A wing hair is an actin-rich, polarized, non-sensory apical projection that protrudes from each of the approximately 30,000 wing epithelial cells. An example of this is found in Drosophila melanogaster. + GOC:mtg_sensu + PMID:11064425 + PMID:12540853 + + + + + imaginal disc-derived wing hair organization and biogenesis + GOC:mah + + + + + wing hair organization and biogenesis + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + The orderly movement of a mesenchymal cell from one site to another that will contribute to the formation of a limb bud. + bf + 2010-02-24T02:05:14Z + biological_process + GO:0035322 + mesenchymal cell migration involved in limb bud formation + + + + + The orderly movement of a mesenchymal cell from one site to another that will contribute to the formation of a limb bud. + GOC:dgh + + + + + + + + + + + + + + + + + + + + A process in which a protein is transported to, or maintained at, a microtubule. + bf + 2010-03-11T11:00:56Z + protein localisation to microtubule + biological_process + GO:0035372 + protein localization to microtubule + + + + + A process in which a protein is transported to, or maintained at, a microtubule. + GOC:bf + GOC:lb + + + + + protein localisation to microtubule + GOC:mah + + + + + + + + + + + + + + + + + + + Binding to chondroitin sulfate, a glycosaminoglycan made up of two alternating monosaccharides: D-glucuronic acid (GlcA) and N-acetyl-D-galactosamine (GalNAc). + bf + 2010-03-12T10:25:34Z + molecular_function + GO:0035374 + chondroitin sulfate binding + + + + + Binding to chondroitin sulfate, a glycosaminoglycan made up of two alternating monosaccharides: D-glucuronic acid (GlcA) and N-acetyl-D-galactosamine (GalNAc). + GOC:kmv + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form de novo blood vessels and tubes. + bf + 2010-04-09T03:53:01Z + biological_process + GO:0035441 + cell migration involved in vasculogenesis + + + + + The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form de novo blood vessels and tubes. + GOC:dgh + + + + + + + + + + + + + + + + + + + The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell. + bf + 2010-05-14T01:14:37Z + GO:0007242 + GO:0007243 + GO:0023013 + GO:0023034 + intracellular signaling chain + intracellular protein kinase cascade + intracellular signal transduction pathway + protein kinase cascade + signal transmission via intracellular cascade + biological_process + intracellular signaling cascade + intracellular signaling pathway + signal transduction via intracellular signaling cascade + GO:0035556 + + intracellular signal transduction + + + + + The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell. + GOC:bf + GOC:jl + GOC:signaling + ISBN:3527303782 + + + + + intracellular signaling chain + ISBN:3527303782 + + + + + intracellular protein kinase cascade + GOC:signaling + + + + + protein kinase cascade + GOC:signaling + + + + + intracellular signaling cascade + GOC:signaling + + + + + + + + + + + + + + + + + + + + + The directed movement of a protein to a specific location within the extracellular region. + bf + 2010-11-09T10:25:08Z + establishment of protein localisation in extracellular region + establishment of protein localization in extracellular region + biological_process + GO:0035592 + establishment of protein localization to extracellular region + + + + + The directed movement of a protein to a specific location within the extracellular region. + GOC:BHF + GOC:bf + + + + + establishment of protein localisation in extracellular region + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the intrahepatic bile ducts over time, from their formation to the mature structure. Intrahepatic bile ducts (bile ducts within the liver) collect bile from bile canaliculi in the liver, and connect to the extrahepatic bile ducts (bile ducts outside the liver). + bf + 2010-12-08T04:10:50Z + IHBD development + intrahepatic biliary duct development + biological_process + GO:0035622 + intrahepatic bile duct development + + + + + The progression of the intrahepatic bile ducts over time, from their formation to the mature structure. Intrahepatic bile ducts (bile ducts within the liver) collect bile from bile canaliculi in the liver, and connect to the extrahepatic bile ducts (bile ducts outside the liver). + GOC:bf + PMID:20614624 + + + + + IHBD development + PMID:20614624 + + + + + intrahepatic biliary duct development + PMID:20614624 + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the cystic duct over time, from its formation to the mature structure. The cystic duct runs from the gall bladder to the common bile duct. + bf + 2010-12-10T01:24:28Z + biological_process + GO:0035628 + cystic duct development + + + + + The progression of the cystic duct over time, from its formation to the mature structure. The cystic duct runs from the gall bladder to the common bile duct. + PMID:20614624 + + + + + + + + + + + + + + + + + + + The deposition of hydroxyapatite, involved in the progression of the skeleton from its formation to its mature state. + bf + 2010-12-20T01:57:31Z + biological_process + GO:0035630 + Bone mineralization can also occur after a fracture and as a response to stress; in these cases, consider using the term 'bone mineralization ; GO:0030282'. + bone mineralization involved in bone maturation + + + + + The deposition of hydroxyapatite, involved in the progression of the skeleton from its formation to its mature state. + GOC:BHF + GOC:bf + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate. + bf + 2011-02-14T11:01:42Z + biological_process + GO:0035675 + neuromast hair cell development + + + + + The process whose specific outcome is the progression of a neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate. + CL:0000856 + + + + + + + + + + + + + + + + + + + + + + + + + + The change in form (cell shape and size) that occurs when a neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. + bf + 2011-02-14T11:06:15Z + biological_process + GO:0035678 + neuromast hair cell morphogenesis + + + + + The change in form (cell shape and size) that occurs when a neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. + CL:0000856 + + + + + + + + + + + + + + + + + + + The bidirectional movement of large protein complexes along microtubules within a cilium that contributes to cilium assembly. + bf + 2011-03-17T10:55:42Z + intraflagellar transport + Reactome:R-HSA-5620924.2 + biological_process + intraciliary transport involved in cilium morphogenesis + intraflagellar transport involved in cilium morphogenesis + GO:0035735 + intraciliary transport involved in cilium assembly + + + + + The bidirectional movement of large protein complexes along microtubules within a cilium that contributes to cilium assembly. + GOC:bf + GOC:cilia + Reactome:R-HSA-5620924.2 + + + + + + + + + + + + + + + + + + + The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to compound eye morphogenesis. + bf + 2011-03-17T10:57:03Z + biological_process + GO:0035736 + cell proliferation involved in compound eye morphogenesis + + + + + The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to compound eye morphogenesis. + GOC:bf + GOC:sart + + + + + + + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the dorsal motor nucleus of the vagus nerve to attain its fully functional state. + bf + 2011-03-29T02:45:50Z + biological_process + GO:0035761 + dorsal motor nucleus of vagus nerve maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the dorsal motor nucleus of the vagus nerve to attain its fully functional state. + GOC:dgh + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the dorsal motor nucleus of the vagus nerve is generated and organized. Morphogenesis pertains to the creation of form. + bf + 2011-03-29T02:47:18Z + biological_process + GO:0035762 + dorsal motor nucleus of vagus nerve morphogenesis + + + + + The process in which the dorsal motor nucleus of the vagus nerve is generated and organized. Morphogenesis pertains to the creation of form. + GOC:dgh + + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to the dorsal motor nucleus of the vagus nerve. This process pertains to the initial formation of a structure from unspecified parts. + bf + 2011-03-29T02:48:26Z + biological_process + GO:0035764 + dorsal motor nucleus of vagus nerve formation + + + + + The process that gives rise to the dorsal motor nucleus of the vagus nerve. This process pertains to the initial formation of a structure from unspecified parts. + GOC:dgh + + + + + + + + + + + + + + + + + + + The orderly movement of a motor neuron precursor cell that contributes to formation of the dorsal motor nucleus of the vagus nerve. + bf + 2011-03-29T02:52:09Z + biological_process + GO:0035765 + motor neuron precursor migration involved in dorsal motor nucleus of vagus nerve formation + + + + + The orderly movement of a motor neuron precursor cell that contributes to formation of the dorsal motor nucleus of the vagus nerve. + GOC:dgh + PMID:21262462 + + + + + + + + + + + + + + + + + + + The regulated release of proinsulin from secretory granules (B granules) in the B cells of the pancreas; accompanied by cleavage of proinsulin to form mature insulin, in response to a glucose stimulus. + bf + 2011-04-01T01:14:40Z + insulin secretion involved in cellular response to glucose + biological_process + GO:0035773 + insulin secretion involved in cellular response to glucose stimulus + + + + + The regulated release of proinsulin from secretory granules (B granules) in the B cells of the pancreas; accompanied by cleavage of proinsulin to form mature insulin, in response to a glucose stimulus. + GOC:bf + GOC:yaf + PMID:8492079 + + + + + insulin secretion involved in cellular response to glucose + GOC:bf + + + + + + + + + + + + + + + + + + + Any process that increases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose. + bf + 2011-04-01T01:49:09Z + positive regulation of insulin secretion in response to glucose + biological_process + GO:0035774 + positive regulation of insulin secretion involved in cellular response to glucose stimulus + + + + + Any process that increases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose. + GOC:bf + GOC:yaf + + + + + positive regulation of insulin secretion in response to glucose + GOC:bf + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the pronephric glomerulus are generated and organized. The pronephric glomerulus is part of the pronephric nephron and is restricted to one body segment. + bf + 2011-04-04T10:59:28Z + biological_process + GO:0035775 + This term is intended for annotation of fish and other organisms which contain a glomerulus as part of the pronephric nephron. It should not be used for annotation of Xenopus, which contains a pronephric glomus rather than a glomerulus. + pronephric glomerulus morphogenesis + + + + + The process in which the anatomical structures of the pronephric glomerulus are generated and organized. The pronephric glomerulus is part of the pronephric nephron and is restricted to one body segment. + GOC:mtg_kidney_jan10 + GOC:yaf + PMID:18787069 + + + + + + + + + + + + + + + + + + + + + The progression of the pronephric proximal tubule over time, from its formation to the mature structure. A pronephric nephron tubule is an epithelial tube that is part of the pronephros. + bf + 2011-04-04T11:02:54Z + biological_process + GO:0035776 + pronephric proximal tubule development + + + + + The progression of the pronephric proximal tubule over time, from its formation to the mature structure. A pronephric nephron tubule is an epithelial tube that is part of the pronephros. + GOC:mtg_kidney_jan10 + GOC:yaf + PMID:18787069 + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the pronephric distal tubule over time, from its formation to the mature structure. A pronephric nephron tubule is an epithelial tube that is part of the pronephros. + bf + 2011-04-04T11:06:01Z + biological_process + GO:0035777 + pronephric distal tubule development + + + + + The process whose specific outcome is the progression of the pronephric distal tubule over time, from its formation to the mature structure. A pronephric nephron tubule is an epithelial tube that is part of the pronephros. + GOC:mtg_kidney_jan10 + GOC:yaf + PMID:18787069 + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an angioblast cell. Angioblasts are one of the two products formed from hemangioblast cells (the other being pluripotent hemopoietic stem cells). + bf + 2011-04-04T11:10:38Z + angioblastic mesenchymal cell differentiation + biological_process + GO:0035779 + angioblast cell differentiation + + + + + The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an angioblast cell. Angioblasts are one of the two products formed from hemangioblast cells (the other being pluripotent hemopoietic stem cells). + CL:0000566 + GOC:yaf + + + + + angioblastic mesenchymal cell differentiation + CL:0000566 + + + + + + + + + + + + + + + + + + + The orderly movement of a cell from one site to another that will contribute to the progression of the kidney over time, from its formation to the mature organ. + bf + 2011-04-06T10:39:52Z + biological_process + GO:0035787 + cell migration involved in kidney development + + + + + The orderly movement of a cell from one site to another that will contribute to the progression of the kidney over time, from its formation to the mature organ. + GOC:bf + GOC:mtg_kidney_jan10 + GOC:yaf + + + + + + + + + + + + + + + + + + + The orderly movement of a cell from one site to another that will contribute to the progression of the metanephric kidney over time, from its formation to the mature organ. + bf + 2011-04-06T10:42:21Z + cell migration involved in metanephric kidney development + biological_process + GO:0035788 + cell migration involved in metanephros development + + + + + The orderly movement of a cell from one site to another that will contribute to the progression of the metanephric kidney over time, from its formation to the mature organ. + GOC:bf + GOC:mtg_kidney_jan10 + GOC:yaf + + + + + cell migration involved in metanephric kidney development + GOC:bf + + + + + + + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the ureter to attain its fully functional state. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut. + bf + 2011-04-14T01:13:39Z + biological_process + GO:0035799 + ureter maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the ureter to attain its fully functional state. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut. + GOC:bf + GOC:mtg_kidney_jan10 + GOC:yaf + PMID:17881463 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the adrenal cortex over time, from its formation to the mature structure. The adrenal cortex is located at the periphery of the adrenal gland and controls glucose and electrolyte metabolism, response to stress and sexual development through the production of different classes of steroid hormones (glucocorticoids, mineralocorticoids and androgens). + bf + 2011-04-18T10:25:39Z + adrenal gland cortex development + biological_process + GO:0035801 + adrenal cortex development + + + + + The process whose specific outcome is the progression of the adrenal cortex over time, from its formation to the mature structure. The adrenal cortex is located at the periphery of the adrenal gland and controls glucose and electrolyte metabolism, response to stress and sexual development through the production of different classes of steroid hormones (glucocorticoids, mineralocorticoids and androgens). + PMID:12185666 + PMID:21115154 + Wikipedia:Adrenal_cortex + + + + + adrenal gland cortex development + MA:0000118 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to the adrenal cortex. This process pertains to the initial formation of a structure from unspecified parts. The adrenogonadal primordium from which the adrenal cortex is formed derives from a condensation of coelomic epithelial cells (the urogenital ridge; the same structure from which gonads and kidney also originate). + bf + 2011-04-18T10:26:49Z + adrenal gland cortex formation + biological_process + GO:0035802 + adrenal cortex formation + + + + + The process that gives rise to the adrenal cortex. This process pertains to the initial formation of a structure from unspecified parts. The adrenogonadal primordium from which the adrenal cortex is formed derives from a condensation of coelomic epithelial cells (the urogenital ridge; the same structure from which gonads and kidney also originate). + PMID:12185666 + PMID:21115154 + + + + + adrenal gland cortex formation + MA:0000118 + + + + + + + + + + + + + + + Construction of an egg coat, a specialized extracellular matrix that surrounds the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development. + bf + 2011-04-19T01:48:43Z + VE formation + ZP assembly + vitelline envelope formation + zona pellucida assembly + biological_process + GO:0035803 + egg coat formation + + + + + Construction of an egg coat, a specialized extracellular matrix that surrounds the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development. + GOC:bf + GOC:sart + GOC:yaf + PMID:16944418 + PMID:17163408 + + + + + VE formation + PMID:16944418 + PMID:17163408 + + + + + ZP assembly + PMID:18420282 + + + + + vitelline envelope formation + PMID:16944418 + + + + + zona pellucida assembly + GOC:yaf + PMID:18420282 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A specialized extracellular matrix that surrounds the plasma membrane of the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development. + bf + 2011-04-19T02:07:23Z + vitelline membrane + zona pellucida + cellular_component + GO:0035805 + egg coat + + + + + A specialized extracellular matrix that surrounds the plasma membrane of the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development. + PMID:16944418 + PMID:17163408 + + + + + vitelline membrane + PMID:16944418 + PMID:17163408 + + + + + zona pellucida + PMID:16944418 + PMID:17163408 + + + + + + + + + + + + + + + + + + + + + Any process that modulates the amount of urine excreted from the body over a unit of time. + bf + 2011-04-20T01:17:38Z + regulation of urinary volume + regulation of urine flow + biological_process + GO:0035809 + regulation of urine volume + + + + + Any process that modulates the amount of urine excreted from the body over a unit of time. + GOC:mtg_25march11 + GOC:yaf + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the cloaca over time, from it's formation to the mature structure. The cloaca is the common chamber into which intestinal, genital and urinary canals open in vertebrates. + bf + 2011-05-06T01:54:35Z + cloacal development + biological_process + GO:0035844 + cloaca development + + + + + The process whose specific outcome is the progression of the cloaca over time, from it's formation to the mature structure. The cloaca is the common chamber into which intestinal, genital and urinary canals open in vertebrates. + GOC:dgh + ISBN:0582227089 + + + + + cloacal development + GOC:bf + + + + + + + + + + + + + + + + + + + + + + + + + + + A process that is carried out at the cellular level and results in the assembly, arrangement of constituent parts, or disassembly of the outer segment of a photoreceptor cell, a sensory cell that reacts to the presence of light. The outer segment of the photoreceptor cell contains the light-absorbing materials. + bf + 2011-05-10T10:44:09Z + photoreceptor cell outer segment organisation + photoreceptor outer segment organization + biological_process + GO:0035845 + photoreceptor cell outer segment organization + + + + + A process that is carried out at the cellular level and results in the assembly, arrangement of constituent parts, or disassembly of the outer segment of a photoreceptor cell, a sensory cell that reacts to the presence of light. The outer segment of the photoreceptor cell contains the light-absorbing materials. + ISBN:0824072820 + PMID:14507858 + + + + + photoreceptor cell outer segment organisation + GOC:mah + + + + + photoreceptor outer segment organization + GOC:bf + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the oviduct epithelium over time from its initial formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism. The oviduct epithelium is the specialized epithelium that lines the oviduct. + bf + 2011-05-10T10:53:05Z + fallopian tube epithelium development + biological_process + GO:0035846 + oviduct epithelium development + + + + + The progression of the oviduct epithelium over time from its initial formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism. The oviduct epithelium is the specialized epithelium that lines the oviduct. + GOC:yaf + http://www.thefreedictionary.com/oviduct + + + + + fallopian tube epithelium development + GOC:yaf + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of an epithelium of the uterus over time from its initial formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. + bf + 2011-05-10T10:57:45Z + uterus epithelial development + biological_process + GO:0035847 + uterine epithelium development + + + + + The progression of an epithelium of the uterus over time from its initial formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. + GOC:bf + GOC:yaf + + + + + uterus epithelial development + GOC:yaf + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which anatomical structures of the oviduct are generated and organized. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism. + bf + 2011-05-10T11:01:20Z + fallopian tube morphogenesis + biological_process + GO:0035848 + oviduct morphogenesis + + + + + The process in which anatomical structures of the oviduct are generated and organized. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism. + GOC:yaf + http://www.thefreedictionary.com/oviduct + + + + + fallopian tube morphogenesis + GOC:yaf + + + + + + + + + + + + + + + + + + + The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an epithelial cell that characterize the cells of the kidney as it progresses from its formation to the mature state. + bf + 2011-05-11T11:34:21Z + biological_process + GO:0035850 + epithelial cell differentiation involved in kidney development + + + + + The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an epithelial cell that characterize the cells of the kidney as it progresses from its formation to the mature state. + GOC:bf + GOC:mtg_kidney_jan10 + GOC:yaf + PMID:16216236 + + + + + + + + + + + + + + + A region of the cilium between the basal body and proximal segment that is characterized by Y-shaped assemblages that connect axonemal microtubules to the ciliary membrane. The ciliary transition zone appears to function as a gate that controls ciliary membrane composition and separates the cytosol from the ciliary plasm. + bf + 2011-05-25T03:09:58Z + cilial transition zone + cilium transition zone + cellular_component + connecting cilium + GO:0035869 + Depending on the species, this region may have a distinct geometrically shaped electron-dense structure within the axonemal lumen visible in electron microscopy images; most animals don't display this inner structure. The axoneme extends through the ciliary transition zone, but only consists of the outer doublets. The central pair, axonemal spokes, and dynein complexes are not found in this part of the ciliary shaft. Note that the connecting cilium of the photoreceptor cells is thought to be equivalent to the transition zone. + ciliary transition zone + + + + + A region of the cilium between the basal body and proximal segment that is characterized by Y-shaped assemblages that connect axonemal microtubules to the ciliary membrane. The ciliary transition zone appears to function as a gate that controls ciliary membrane composition and separates the cytosol from the ciliary plasm. + GOC:cilia + GOC:kmv + PMID:21422230 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a nail over time, from its formation to the mature structure. A nail is a horn-like envelope covering the outer end of a finger or toe, and consists of the nail plate, the nail matrix and the nail bed below it, and the grooves surrounding it. + bf + 2011-05-31T02:30:34Z + biological_process + GO:0035878 + nail development + + + + + The process whose specific outcome is the progression of a nail over time, from its formation to the mature structure. A nail is a horn-like envelope covering the outer end of a finger or toe, and consists of the nail plate, the nail matrix and the nail bed below it, and the grooves surrounding it. + GOC:bf + ISBN:0323025781 + UBERON:0001705 + Wikipedia:Nail_(anatomy) + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of an amacrine cell, an interneuron generated in the inner nuclear layer (INL) of the vertebrate retina. Amacrine cells integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. Amacrine cells lack large axons. + bf + 2011-06-06T11:32:50Z + amacrine neuron differentiation + biological_process + GO:0035881 + amacrine cell differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized features of an amacrine cell, an interneuron generated in the inner nuclear layer (INL) of the vertebrate retina. Amacrine cells integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. Amacrine cells lack large axons. + CL:0000561 + GOC:bf + + + + + amacrine neuron differentiation + CL:0000561 + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an enteroendocrine cell. Enteroendocrine cells are hormonally active epithelial cells in the gut that constitute the diffuse neuroendocrine system. + bf + 2011-06-06T11:48:51Z + biological_process + GO:0035883 + enteroendocrine cell differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an enteroendocrine cell. Enteroendocrine cells are hormonally active epithelial cells in the gut that constitute the diffuse neuroendocrine system. + CL:0000164 + GOC:bf + + + + + + + + + The regulated release of parathyroid hormone into the circulatory system. + bf + 2011-06-22T09:28:54Z + PTH secretion + parathormone secretion + parathyrin secretion + biological_process + GO:0035898 + parathyroid hormone secretion + + + + + The regulated release of parathyroid hormone into the circulatory system. + GOC:cjm + PMID:12171519 + PMID:21164021 + + + + + PTH secretion + PMID:12171519 + PR:000013429 + + + + + parathormone secretion + PR:000013429 + + + + + parathyrin secretion + PR:000013429 + + + + + + + + + + + + + + + + + + + + The progression of the aorta over time, from its initial formation to the mature structure. An aorta is an artery that carries blood from the heart to other parts of the body. + bf + 2011-06-24T11:00:07Z + biological_process + GO:0035904 + aorta development + + + + + The progression of the aorta over time, from its initial formation to the mature structure. An aorta is an artery that carries blood from the heart to other parts of the body. + GOC:bf + GOC:dgh + MA:0000062 + UBERON:0000947 + Wikipedia:Aorta + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the ascending aorta over time, from its initial formation to the mature structure. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once. + bf + 2011-06-24T11:02:01Z + biological_process + GO:0035905 + ascending aorta development + + + + + The progression of the ascending aorta over time, from its initial formation to the mature structure. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once. + GOC:bf + GOC:dgh + MA:0002570 + UBERON:0001496 + Wikipedia:Ascending_aorta + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the descending aorta over time, from its initial formation to the mature structure. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once. + bf + 2011-06-24T11:05:22Z + biological_process + GO:0035906 + descending aorta development + + + + + The progression of the descending aorta over time, from its initial formation to the mature structure. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once. + GOC:bf + GOC:dgh + MA:0002571 + UBERON:0001514 + Wikipedia:Descending_aorta + + + + + + + + + + + + + + + + + + + + The progression of the dorsal aorta over time, from its initial formation to the mature structure. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once. + bf + 2011-06-24T11:07:01Z + biological_process + GO:0035907 + dorsal aorta development + + + + + The progression of the dorsal aorta over time, from its initial formation to the mature structure. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once. + GOC:bf + GOC:dgh + UBERON:0005805 + Wikipedia:Aorta + ZFA:0000014 + + + + + + + + + + + + + + + + + + + + The progression of the ventral aorta over time, from its initial formation to the mature structure. The ventral aorta is a blood vessel in a single-pass circulatory system that carries de-oxygenated blood from the heart to the gills. In a single-pass circulatory system blood passes once through the heart to supply the body once. + bf + 2011-06-24T11:08:49Z + biological_process + GO:0035908 + ventral aorta development + + + + + The progression of the ventral aorta over time, from its initial formation to the mature structure. The ventral aorta is a blood vessel in a single-pass circulatory system that carries de-oxygenated blood from the heart to the gills. In a single-pass circulatory system blood passes once through the heart to supply the body once. + GOC:bf + GOC:dgh + UBERON:0003085 + Wikipedia:Aorta + ZFA:0000604 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of an aorta are generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body. + bf + 2011-06-24T11:11:11Z + biological_process + GO:0035909 + aorta morphogenesis + + + + + The process in which the anatomical structures of an aorta are generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body. + GOC:bf + GOC:dgh + MA:0000062 + UBERON:0000947 + Wikipedia:Aorta + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the ascending aorta are generated and organized. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once. + bf + 2011-06-24T11:14:52Z + biological_process + GO:0035910 + ascending aorta morphogenesis + + + + + The process in which the anatomical structures of the ascending aorta are generated and organized. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once. + GOC:bf + GOC:dgh + MA:0002570 + UBERON:0001496 + Wikipedia:Ascending_aorta + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the descending aorta are generated and organized. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once. + bf + 2011-06-24T11:19:24Z + biological_process + GO:0035911 + descending aorta morphogenesis + + + + + The process in which the anatomical structures of the descending aorta are generated and organized. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once. + GOC:bf + GOC:dgh + MA:0002571 + UBERON:0001514 + Wikipedia:Descending_aorta + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the dorsal aorta are generated and organized. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once. + bf + 2011-06-24T11:22:14Z + biological_process + GO:0035912 + dorsal aorta morphogenesis + + + + + The process in which the anatomical structures of the dorsal aorta are generated and organized. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once. + GOC:bf + GOC:dgh + UBERON:0005805 + Wikipedia:Aorta + ZFA:0000014 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the ventral aorta are generated and organized. The ventral aorta is a blood vessel in a single-pass circulatory system that carries de-oxygenated blood from the heart to the gills. In a single-pass circulatory system blood passes once through the heart to supply the body once. + bf + 2011-06-24T11:24:36Z + biological_process + GO:0035913 + ventral aorta morphogenesis + + + + + The process in which the anatomical structures of the ventral aorta are generated and organized. The ventral aorta is a blood vessel in a single-pass circulatory system that carries de-oxygenated blood from the heart to the gills. In a single-pass circulatory system blood passes once through the heart to supply the body once. + GOC:bf + GOC:dgh + UBERON:0003085 + Wikipedia:Aorta + ZFA:0000604 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle cell, a somatic cell located in skeletal muscle. + bf + 2011-06-24T02:36:19Z + biological_process + GO:0035914 + skeletal muscle cell differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle cell, a somatic cell located in skeletal muscle. + CL:0000188 + GOC:BHF + GOC:vk + + + + + + + + + + + + + + + + + + + + + The regulated release of any steroid that acts as a hormone into the circulatory system. + bf + 2011-07-20T01:01:00Z + biological_process + GO:0035929 + steroid hormone secretion + + + + + The regulated release of any steroid that acts as a hormone into the circulatory system. + GOC:sl + + + + + + + + + + + + + + + + + + + + The regulated release of any corticosteroid hormone into the circulatory system. + bf + 2011-07-20T01:03:22Z + corticosteroid secretion + biological_process + GO:0035930 + corticosteroid hormone secretion + + + + + The regulated release of any corticosteroid hormone into the circulatory system. + GOC:sl + + + + + corticosteroid secretion + GOC:bf + + + + + + + + + + + + + + + + + + + + The regulated release of any mineralocorticoid into the circulatory system. Mineralocorticoids are a class of steroid hormones that regulate water and electrolyte metabolism. + bf + 2011-07-20T01:04:59Z + biological_process + GO:0035931 + mineralocorticoid secretion + + + + + The regulated release of any mineralocorticoid into the circulatory system. Mineralocorticoids are a class of steroid hormones that regulate water and electrolyte metabolism. + GOC:sl + + + + + + + + + + + + + + + + + + + + + The regulated release of aldosterone into the circulatory system. Aldosterone is a pregnane-based steroid hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts on the distal tubules and collecting ducts of the kidney to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. The overall effect of aldosterone is to increase reabsorption of ions and water in the kidney. + bf + 2011-07-20T01:06:24Z + biological_process + GO:0035932 + aldosterone secretion + + + + + The regulated release of aldosterone into the circulatory system. Aldosterone is a pregnane-based steroid hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts on the distal tubules and collecting ducts of the kidney to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. The overall effect of aldosterone is to increase reabsorption of ions and water in the kidney. + GOC:sl + + + + + + + + + + + + + + + + + + + + The regulated release of any glucocorticoid hormone into the circulatory system. Glucocorticoids are a class of steroid hormones that regulate a variety of physiological processes, in particular control of the concentration of glucose in blood. + bf + 2011-07-20T01:08:37Z + biological_process + GO:0035933 + glucocorticoid secretion + + + + + The regulated release of any glucocorticoid hormone into the circulatory system. Glucocorticoids are a class of steroid hormones that regulate a variety of physiological processes, in particular control of the concentration of glucose in blood. + GOC:sl + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires the specialized features of an endoderm cell, a cell of the inner of the three germ layers of the embryo. + bf + 2011-08-25T04:50:36Z + endoderm cell differentiation + biological_process + GO:0035987 + endodermal cell differentiation + + + + + The process in which a relatively unspecialized cell acquires the specialized features of an endoderm cell, a cell of the inner of the three germ layers of the embryo. + CL:0000223 + GOC:yaf + PMID:17624332 + + + + + endoderm cell differentiation + CL:0000223 + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a tendon over time, from its formation to the mature structure. A tendon is a fibrous, strong, connective tissue that connects muscle to bone or integument and is capable of withstanding tension. Tendons and muscles work together to exert a pulling force. + bf + 2011-08-26T04:14:30Z + biological_process + sinew development + GO:0035989 + tendon development + + + + + The process whose specific outcome is the progression of a tendon over time, from its formation to the mature structure. A tendon is a fibrous, strong, connective tissue that connects muscle to bone or integument and is capable of withstanding tension. Tendons and muscles work together to exert a pulling force. + GOC:yaf + PMID:21412429 + UBERON:0000043 + + + + + sinew development + UBERON:0000043 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to a tendon. This process pertains to the initial formation of a tendon from unspecified parts. + bf + 2011-08-30T01:35:10Z + biological_process + GO:0035992 + tendon formation + + + + + The process that gives rise to a tendon. This process pertains to the initial formation of a tendon from unspecified parts. + GOC:yaf + PMID:17567668 + UBERON:0000043 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the deltoid tuberosity over time, from its formation to the mature structure. The deltoid tuberosity is the region on the shaft of the humerus to which the deltoid muscle attaches. The deltoid tuberosity develops through endochondral ossification in a two-phase process; an initiating tendon-dependent phase, and a muscle-dependent growth phase. + bf + 2011-08-30T01:46:53Z + biological_process + GO:0035993 + deltoid tuberosity development + + + + + The process whose specific outcome is the progression of the deltoid tuberosity over time, from its formation to the mature structure. The deltoid tuberosity is the region on the shaft of the humerus to which the deltoid muscle attaches. The deltoid tuberosity develops through endochondral ossification in a two-phase process; an initiating tendon-dependent phase, and a muscle-dependent growth phase. + GOC:yaf + PMID:17567668 + UBERON:0002498 + Wikipedia:Deltoid_tuberosity + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of a limb joint are generated and organized. A limb joint is a flexible region that separates the rigid sections of a limb to allow movement in a controlled manner. + bf + 2011-10-13T04:52:59Z + knee morphogenesis + leg joint morphogenesis + biological_process + GO:0036022 + limb joint morphogenesis + + + + + The process in which the anatomical structures of a limb joint are generated and organized. A limb joint is a flexible region that separates the rigid sections of a limb to allow movement in a controlled manner. + GOC:bf + + + + + knee morphogenesis + GOC:bf + + + + + leg joint morphogenesis + GOC:bf + + + + + + + + + The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance, that does not require the replacement of preexisting tissues. + bf + 2011-12-19T01:47:22Z + biological_process + GO:0036072 + direct ossification + + + + + The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance, that does not require the replacement of preexisting tissues. + GO_REF:0000034 + + + + + + + + + Intramembranous ossification from the surface of a cartilage element as the perichondrium becomes a periosteum, without replacement of cartilage. + bf + 2011-12-19T01:49:38Z + biological_process + GO:0036073 + perichondral ossification + + + + + Intramembranous ossification from the surface of a cartilage element as the perichondrium becomes a periosteum, without replacement of cartilage. + GO_REF:0000034 + + + + + + + + + Ossification that requires the replacement of a preexisting tissue prior to bone tissue formation. + bf + 2011-12-19T01:53:16Z + indirect ossification + biological_process + GO:0036075 + replacement ossification + + + + + Ossification that requires the replacement of a preexisting tissue prior to bone tissue formation. + GO_REF:0000034 + + + + + indirect ossification + GO_REF:0000034 + + + + + + + + + + + + + + + + + + + + + + + + + + The multiplication or reproduction of germ cells, reproductive cells in multicellular organisms, resulting in the expansion of a cell population. + bf + 2012-01-17T04:06:27Z + biological_process + GO:0036093 + germ cell proliferation + + + + + The multiplication or reproduction of germ cells, reproductive cells in multicellular organisms, resulting in the expansion of a cell population. + CL:0000586 + GOC:kmv + + + + + + + + + Binding to a small molecule, any low molecular weight, monomeric, non-encoded molecule. + bf + 2012-01-17T04:20:34Z + molecular_function + GO:0036094 + + + Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides. + small molecule binding + + + + + Binding to a small molecule, any low molecular weight, monomeric, non-encoded molecule. + GOC:curators + GOC:pde + GOC:pm + + + + + + + + + + + + + + + + + + + + The orderly movement of a Schwann cell from one site to another. A Schwann cell is a glial cell that ensheathes axons of neuron in the peripheral nervous system and is necessary for their maintainance and function. + bf + 2012-03-06T10:44:39Z + biological_process + GO:0036135 + Schwann cell migration + + + + + The orderly movement of a Schwann cell from one site to another. A Schwann cell is a glial cell that ensheathes axons of neuron in the peripheral nervous system and is necessary for their maintainance and function. + CL:0002573 + PMID:20335460 + + + + + + + + + + + + + + + + + + + + The process of regulating the proliferation and elimination of dendritic cells such that the total number of dendritic cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. + bf + 2012-03-12T11:05:36Z + biological_process + DC homeostasis + GO:0036145 + dendritic cell homeostasis + + + + + The process of regulating the proliferation and elimination of dendritic cells such that the total number of dendritic cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. + CL:0000451 + GOC:uh + PMID:12570827 + PMID:19176316 + + + + + DC homeostasis + PMID:19176316 + + + + + + + + + A digestive process in which food, usually grass or hay, is swallowed into a multi-compartmented stomach, regurgitated, chewed again, and swallowed again. + bf + 2012-03-13T04:35:19Z + digestive rumination + biological_process + GO:0036147 + rumination + + + + + A digestive process in which food, usually grass or hay, is swallowed into a multi-compartmented stomach, regurgitated, chewed again, and swallowed again. + GOC:maf + Wikipedia:Rumination + + + + + digestive rumination + Wikipedia:Rumination + + + + + + + + + + + + + + + + + + + + The regulated release of calcitonin, a peptide hormone that participates in calcium and phosphorus metabolism, from a cell. + bf + 2012-03-26T01:30:32Z + biological_process + GO:0036161 + calcitonin secretion + + + + + The regulated release of calcitonin, a peptide hormone that participates in calcium and phosphorus metabolism, from a cell. + GOC:cjm + + + + + + + + + + + + + + + + + + + A prolongation or process extending from a muscle cell. A muscle cell is a mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns. + bf + 2012-04-20T10:20:47Z + myocyte projection + muscle arm + myopodia + cellular_component + GO:0036194 + muscle cell projection + + + + + A prolongation or process extending from a muscle cell. A muscle cell is a mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns. + CL:0000187 + GOC:kmv + PMID:15930100 + PMID:22464329 + + + + + myocyte projection + CL:0000187 + + + + + muscle arm + GOC:kmv + + + + + myopodia + GOC:kmv + + + + + + + + + + + + + + + + + + + + The portion of the plasma membrane surrounding a muscle cell projection. + bf + 2012-04-20T10:21:51Z + cellular_component + GO:0036195 + muscle cell projection membrane + + + + + The portion of the plasma membrane surrounding a muscle cell projection. + CL:0000187 + GOC:kmv + PMID:15930100 + PMID:22464329 + + + + + + + + + + The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification). + https://github.com/geneontology/go-ontology/issues/23112 + bf + 2012-04-26T01:47:12Z + GO:0006464 + cellular protein modification process + process resulting in protein modification + protein modification + biological_process + GO:0036211 + + + + + + + protein modification process + + + + + The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification). + GOC:bf + GOC:jl + + + + + protein modification + GOC:bf + + + + + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen. + bf + 2012-07-20T01:05:46Z + response to lowered oxygen levels + biological_process + GO:0036293 + This term should be used when a decrease in oxygen levels is not considered a stress response. For a hypoxic stress response, consider instead 'response to hypoxia ; GO:0001666'. + response to decreased oxygen levels + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen. + GOC:al + + + + + response to lowered oxygen levels + GOC:bf + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the atrioventricular canal over time, from its formation to the mature structure. The atrioventricular canal is the part of the heart connecting the atrium to the cardiac ventricle. + bf + 2012-08-08T09:55:37Z + biological_process + GO:0036302 + atrioventricular canal development + + + + + The progression of the atrioventricular canal over time, from its formation to the mature structure. The atrioventricular canal is the part of the heart connecting the atrium to the cardiac ventricle. + GOC:BHF + GOC:gr + PMID:14701881 + UBERON:0002087 + ZFA:0001315 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of lymph vessels are generated and organized. The lymph vessel is the vasculature carrying lymph. + bf + 2012-08-08T10:08:47Z + biological_process + GO:0036303 + lymph vessel morphogenesis + + + + + The process in which the anatomical structures of lymph vessels are generated and organized. The lymph vessel is the vasculature carrying lymph. + GOC:BHF + GOC:gr + PMID:18093989 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the umbilical cord are generated and organized. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta. + bf + 2012-08-08T10:12:11Z + biological_process + GO:0036304 + umbilical cord morphogenesis + + + + + The process in which the anatomical structures of the umbilical cord are generated and organized. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta. + GOC:BHF + GOC:gr + PMID:15107403 + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of an ameloblast, a cylindrical epithelial cell in the innermost layer of the enamel organ. + bf + 2012-08-08T13:49:15Z + biological_process + GO:0036305 + ameloblast differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized features of an ameloblast, a cylindrical epithelial cell in the innermost layer of the enamel organ. + CL:0000059 + + + + + + + + + + + + + + + + + + + + Any biological process involved in the maintenance of the steady-state number of hepatocytes within a population of cells. Hepatocytes are specialized epithelial cells of the liver that are organized into interconnected plates called lobules. + bf + 2012-09-05T10:17:07Z + biological_process + GO:0036333 + hepatocyte homeostasis + + + + + Any biological process involved in the maintenance of the steady-state number of hepatocytes within a population of cells. Hepatocytes are specialized epithelial cells of the liver that are organized into interconnected plates called lobules. + CL:0000182 + GOC:nhn + PMID:19878874 + + + + + + + + + + + + + + + + + + + + The movement of a dendritic cell within or between different tissues and organs of the body. + bf + 2012-09-05T10:24:46Z + biological_process + GO:0036336 + dendritic cell migration + + + + + The movement of a dendritic cell within or between different tissues and organs of the body. + CL:0000451 + GOC:nhn + PMID:19339990 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a post-anal tail is generated and organized. A post-anal tail is a muscular region of the body that extends posterior to the anus. The post-anal tail may aid locomotion and balance. + bf + 2012-09-11T13:54:49Z + biological_process + GO:0036342 + post-anal tail morphogenesis + + + + + The process in which a post-anal tail is generated and organized. A post-anal tail is a muscular region of the body that extends posterior to the anus. The post-anal tail may aid locomotion and balance. + GOC:bf + GOC:kmv + Wikipedia:Chordate + + + + + + + + + Generation and organization of a platelet, a non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation. + bf + 2012-09-11T15:15:35Z + biological_process + GO:0036344 + platelet morphogenesis + + + + + Generation and organization of a platelet, a non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation. + CL:0000233 + GOC:BHF + GOC:vk + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for a platelet to attain its fully functional state. A platelet is a non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation. + bf + 2012-09-11T15:23:11Z + biological_process + GO:0036345 + platelet maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for a platelet to attain its fully functional state. A platelet is a non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation. + CL:0000233 + GOC:BHF + GOC:vk + + + + + + + + + + + + + + + + + + + + + Any of the smallest contractile units of a myofibril (striated muscle fiber). + bf + 2013-05-22T14:39:06Z + striated muscle filament + cellular_component + GO:0036379 + myofilament + + + + + Any of the smallest contractile units of a myofibril (striated muscle fiber). + Wikipedia:Myofilament + + + + + striated muscle filament + GOC:bf + + + + + + + + + + + + + + + The region of a neuron that includes the cell body (cell soma) and dendrite(s), but excludes the axon. + bf + 2014-07-24T10:06:19Z + cellular_component + GO:0036477 + somatodendritic compartment + + + + + The region of a neuron that includes the cell body (cell soma) and dendrite(s), but excludes the axon. + GOC:PARL + GOC:pad + + + + + + + + + + + + + + + + + + + + + + + + + + The characteristic movement of trunk neural crest cells from the neural tube to other locations in the vertebrate embryo. + bf + 2014-08-26T15:27:44Z + trunk NCC migration + biological_process + GO:0036484 + trunk neural crest cell migration + + + + + The characteristic movement of trunk neural crest cells from the neural tube to other locations in the vertebrate embryo. + GOC:PARL + GOC:bf + GOC:mat + PMID:2387238 + + + + + trunk NCC migration + PMID:2387238 + + + + + + + + + + + + + + + + + + + + + + + + + + The joining of two lipid bilayers that surround the Golgi apparatus to form a single Golgi membrane. + bf + 2015-05-21T10:05:06Z + membrane fusion involved in Golgi reassembly + post-mitotic fusion of Golgi membranes + biological_process + GO:0036504 + Golgi membrane fusion + + + + + The joining of two lipid bilayers that surround the Golgi apparatus to form a single Golgi membrane. + GOC:PARL + GOC:bf + PMID:12473691 + + + + + membrane fusion involved in Golgi reassembly + GOC:bf + + + + + post-mitotic fusion of Golgi membranes + PMID:10811609 + + + + + + + + + Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response. + bf + 2011-08-01T02:45:27Z + GO:0004872 + GO:0019041 + receptor activity + receptor activity involved in signal transduction + signalling receptor activity + molecular_function + GO:0038023 + + + + + + + + + signaling receptor activity + + + + + Receiving a signal and transmitting it in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response. + GOC:bf + GOC:signaling + + + + + receptor activity involved in signal transduction + GOC:bf + + + + + + + + + A G protein-coupled receptor signaling pathway initiated by somatostatin binding to the somatostatin receptor (SSTR) on the surface of a target cell, and ending with the regulation of a downstream cellular process. + bf + 2012-06-12T10:30:01Z + SST receptor signaling pathway + biological_process + SSTR signaling pathway + GO:0038169 + In addition to somatostatin (SST), the somatostatin receptors (SSTRs) can also be activated by the agonist cortistatin (CST). For signal transduction specifically initiated by the ligand somatostatin, consider instead annotating to the child term 'somatostatin signaling pathway ; GO:0038170'. + somatostatin receptor signaling pathway + + + + + A G protein-coupled receptor signaling pathway initiated by somatostatin binding to the somatostatin receptor (SSTR) on the surface of a target cell, and ending with the regulation of a downstream cellular process. + GOC:jc + PMID:18006219 + PMID:8769369 + + + + + SST receptor signaling pathway + GOC:bf + + + + + SSTR signaling pathway + GOC:bf + + + + + + + + + + + + + + + + A G protein-coupled receptor signaling pathway initiated by somatostatin binding to a somatostatin receptor (SSTR), and ending with the regulation of a downstream cellular process, e.g. transcription. + bf + 2012-06-12T10:33:21Z + SRIF signaling pathway + SST signaling pathway + somatostatin signalling pathway + somatostatin-activated somatostatin receptor signaling pathway + somatostatin-mediated signaling pathway + somatotrophin release inhibiting factor signaling pathway + biological_process + GO:0038170 + somatostatin signaling pathway + + + + + A G protein-coupled receptor signaling pathway initiated by somatostatin binding to a somatostatin receptor (SSTR), and ending with the regulation of a downstream cellular process, e.g. transcription. + GOC:bf + GOC:nhn + GOC:signaling + PMID:18006219 + Wikipedia:Somatostatin + + + + + SRIF signaling pathway + Wikipedia:Somatostatin + + + + + SST signaling pathway + Wikipedia:Somatostatin + + + + + somatostatin signalling pathway + GOC:bf + + + + + somatostatin-activated somatostatin receptor signaling pathway + GOC:bf + + + + + somatostatin-mediated signaling pathway + GOC:bf + + + + + somatotrophin release inhibiting factor signaling pathway + Wikipedia:Somatostatin + + + + + + + + + Combining with a pathogen-associated molecular pattern (PAMP), a structure conserved among microbial species to initiate an innate immune response. + https://github.com/geneontology/go-ontology/issues/17995 + https://github.com/geneontology/go-ontology/issues/18588 + bf + 2013-05-29T15:24:44Z + GO:0008329 + Wikipedia:Pattern_recognition_receptor + PRR + PRR activity + MAMP receptor activity + PAMP receptor activity + microbe-associated molecular pattern receptor activity + pathogen associated molecular pattern receptor activity + molecular_function + macrophage receptor activity + signaling pattern recognition receptor activity + GO:0038187 + pattern recognition receptor activity + + + + + Combining with a pathogen-associated molecular pattern (PAMP), a structure conserved among microbial species to initiate an innate immune response. + GOC:ar + GOC:bf + + + + + PRR activity + Wikipedia:Pattern_recognition_receptor + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The developmental process pertaining to the initial formation of a pronephric nephron tubule from unspecified parts. A pronephric nephron tubule is an epithelial tube that is part of a nephron in the pronephros. + bf + 2010-07-02T09:37:27Z + pronephric tubule formation + pronephros tubule formation + biological_process + GO:0039006 + pronephric nephron tubule formation + + + + + The developmental process pertaining to the initial formation of a pronephric nephron tubule from unspecified parts. A pronephric nephron tubule is an epithelial tube that is part of a nephron in the pronephros. + GOC:mtg_kidney_jan10 + + + + + pronephric tubule formation + GOC:mtg_kidney_jan10 + + + + + pronephros tubule formation + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the pronephric nephron are generated and organized. A pronephric nephron is the functional unit of the pronephros. + bf + 2010-07-02T09:38:53Z + biological_process + GO:0039007 + pronephric nephron morphogenesis + + + + + The process in which the anatomical structures of the pronephric nephron are generated and organized. A pronephric nephron is the functional unit of the pronephros. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of a pronephric nephron tubule are generated and organized from an epithelium. A pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron. + bf + 2010-07-02T09:45:55Z + biological_process + GO:0039008 + pronephric nephron tubule morphogenesis + + + + + The process in which the anatomical structures of a pronephric nephron tubule are generated and organized from an epithelium. A pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron. + GOC:mtg_kidney_jan10 + ZFA:00001558 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the rectal diverticulum over time, from its formation to the mature structure. The rectal diverticulum is an outgrowth of the cloaca and links the pronephric kidney to the exterior. + bf + 2010-07-02T09:48:58Z + pronephric rectal diverticulum development + biological_process + GO:0039009 + rectal diverticulum development + + + + + The process whose specific outcome is the progression of the rectal diverticulum over time, from its formation to the mature structure. The rectal diverticulum is an outgrowth of the cloaca and links the pronephric kidney to the exterior. + GOC:mtg_kidney_jan10 + PMID:10535314 + PMID:18226983 + XAO:0001015 + + + + + pronephric rectal diverticulum development + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of a pronephric nephron proximal tubule are generated and organized. A pronephric nephron tubule is an epithelial tube that is part of the pronephros. + bf + 2010-07-02T09:53:12Z + pronephros proximal tubule morphogenesis + biological_process + GO:0039011 + pronephric proximal tubule morphogenesis + + + + + The process in which the anatomical structures of a pronephric nephron proximal tubule are generated and organized. A pronephric nephron tubule is an epithelial tube that is part of the pronephros. + GOC:mtg_kidney_jan10 + + + + + pronephros proximal tubule morphogenesis + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the pronephric sinus over time, from its formation to the mature structure. The pronephric sinus is an ill-defined capillary network that lies between the pronephric tubules. + bf + 2010-07-02T09:55:23Z + biological_process + GO:0039012 + pronephric sinus development + + + + + The process whose specific outcome is the progression of the pronephric sinus over time, from its formation to the mature structure. The pronephric sinus is an ill-defined capillary network that lies between the pronephric tubules. + GOC:mtg_kidney_jan10 + PMID:10535314 + XAO:0000385 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of a pronephric nephron distal tubule are generated and organized. A pronephric nephron tubule is an epithelial tube that is part of the pronephros. + bf + 2010-07-02T09:58:03Z + biological_process + GO:0039013 + pronephric distal tubule morphogenesis + + + + + The process in which the anatomical structures of a pronephric nephron distal tubule are generated and organized. A pronephric nephron tubule is an epithelial tube that is part of the pronephros. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephros as it progresses from its formation to the mature state. + bf + 2010-07-02T09:59:25Z + cell differentiation involved in pronephric kidney development + biological_process + GO:0039014 + cell differentiation involved in pronephros development + + + + + The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephros as it progresses from its formation to the mature state. + GOC:mtg_kidney_jan10 + + + + + cell differentiation involved in pronephric kidney development + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + The multiplication or reproduction of cells, resulting in the expansion of the population in the pronephros. + bf + 2010-07-02T10:01:49Z + cell proliferation involved in pronephric kidney development + biological_process + GO:0039015 + cell proliferation involved in pronephros development + + + + + The multiplication or reproduction of cells, resulting in the expansion of the population in the pronephros. + GOC:mtg_kidney_jan10 + + + + + cell proliferation involved in pronephric kidney development + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + Any process that mediates the transfer of information from one cell to another and contributes to the progression of the pronephros over time, from its formation to the mature organ. + bf + 2010-07-02T10:03:16Z + cell-cell signaling involved in pronephric kidney development + cell-cell signalling involved in pronephros development + biological_process + GO:0039016 + cell-cell signaling involved in pronephros development + + + + + Any process that mediates the transfer of information from one cell to another and contributes to the progression of the pronephros over time, from its formation to the mature organ. + GOC:mtg_kidney_jan10 + + + + + cell-cell signaling involved in pronephric kidney development + GOC:mtg_kidney_jan10 + + + + + cell-cell signalling involved in pronephros development + GOC:mah + + + + + + + + + + + + + + + + + + + Any developmental process that results in the creation of defined areas or spaces within the pronephros to which cells respond and eventually are instructed to differentiate. + bf + 2010-07-02T10:04:39Z + pattern specification involved in pronephric kidney development + biological_process + GO:0039017 + pattern specification involved in pronephros development + + + + + Any developmental process that results in the creation of defined areas or spaces within the pronephros to which cells respond and eventually are instructed to differentiate. + GOC:mtg_kidney_jan10 + + + + + pattern specification involved in pronephric kidney development + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the nephrostome over time, from its formation to the mature structure. The nephrostome is the opening of the pronephros into the body cavity. + bf + 2010-07-02T10:08:16Z + biological_process + GO:0039018 + nephrostome development + + + + + The process whose specific outcome is the progression of the nephrostome over time, from its formation to the mature structure. The nephrostome is the opening of the pronephros into the body cavity. + GOC:mtg_kidney_jan10 + PMID:14686690 + PMID:15647339 + XAO:0000062 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the pronephric nephron over time, from its formation to the mature structure. A pronephric nephron is the functional unit of the pronephros. + bf + 2010-07-02T10:10:20Z + biological_process + GO:0039019 + pronephric nephron development + + + + + The process whose specific outcome is the progression of the pronephric nephron over time, from its formation to the mature structure. A pronephric nephron is the functional unit of the pronephros. + GOC:mtg_kidney_jan10 + XAO:00002785 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a pronephric nephron tubule over time, from its formation to the mature structure. The pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron and connects the filtration unit (glomerulus or glomus) of the pronephros to the pronephric duct. + bf + 2010-07-02T10:11:36Z + biological_process + GO:0039020 + pronephric nephron tubule development + + + + + The process whose specific outcome is the progression of a pronephric nephron tubule over time, from its formation to the mature structure. The pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron and connects the filtration unit (glomerulus or glomus) of the pronephros to the pronephric duct. + GOC:mtg_kidney_jan10 + PMID:19909807 + PMID:9268568 + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the glomerulus of the pronephric kidney over time from its initial formation until its mature state. The pronephric glomerulus is part of the pronephric nephron and is restricted to one body segment. + bf + 2010-07-02T10:13:38Z + biological_process + GO:0039021 + This term is intended for annotation of fish and other organisms which contain a glomerulus as part of the pronephric nephron. It should not be used for annotation of Xenopus, which contains a pronephric glomus rather than a glomerulus. + pronephric glomerulus development + + + + + The progression of the glomerulus of the pronephric kidney over time from its initial formation until its mature state. The pronephric glomerulus is part of the pronephric nephron and is restricted to one body segment. + GOC:dgh + GOC:mtg_kidney_jan10 + ZFA:00001557 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the pronephric duct over time, from its formation to the mature structure. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the pronephric kidney. + bf + 2010-07-02T10:15:03Z + biological_process + GO:0039022 + pronephric duct development + + + + + The process whose specific outcome is the progression of the pronephric duct over time, from its formation to the mature structure. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the pronephric kidney. + GOC:mtg_kidney_jan10 + PMID:15647339 + XAO:0000063 + ZFA:0000150 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the pronephric duct are generated and organized. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the kidney. + bf + 2010-07-02T10:18:09Z + biological_process + GO:0039023 + pronephric duct morphogenesis + + + + + The process in which the anatomical structures of the pronephric duct are generated and organized. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the kidney. + GOC:mtg_kidney_jan10 + XAO:0000063 + ZFA:0000150 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Synthesis and deposition of a collagen and cuticulin-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this process is found in Caenorhabditis elegans. + collagen and cuticulin-based cuticle anabolism + collagen and cuticulin-based cuticle biosynthetic process + collagen and cuticulin-based cuticle formation + collagen and cuticulin-based cuticle synthesis + biological_process + GO:0040002 + collagen and cuticulin-based cuticle development + + + + + Synthesis and deposition of a collagen and cuticulin-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this process is found in Caenorhabditis elegans. + GOC:mtg_sensu + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Synthesis and deposition of a chitin-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this process is found in Drosophila melanogaster. + chitin-based cuticle anabolism + chitin-based cuticle biosynthetic process + chitin-based cuticle formation + chitin-based cuticle synthesis + biological_process + GO:0040003 + chitin-based cuticle development + + + + + Synthesis and deposition of a chitin-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this process is found in Drosophila melanogaster. + GOC:mtg_sensu + + + + + + + + + + + + + + + + + + + + + + The increase in size or mass of an entire organism, a part of an organism or a cell. + GO:0048590 + biological_process + growth pattern + non-developmental growth + GO:0040007 + + + + + See also the biological process term 'cell growth ; GO:0016049'. + growth + + + + + The increase in size or mass of an entire organism, a part of an organism or a cell. + GOC:bf + GOC:ma + + + + + non-developmental growth + GOC:mah + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development. + biological_process + GO:0040008 + regulation of growth + + + + + Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development. + GOC:ems + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Self-propelled movement of a cell or organism from one location to another. + + biological_process + GO:0040011 + + + locomotion + + + + + Self-propelled movement of a cell or organism from one location to another. + GOC:dgh + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of locomotion of a cell or organism. + biological_process + GO:0040012 + regulation of locomotion + + + + + Any process that modulates the frequency, rate or extent of locomotion of a cell or organism. + GOC:ems + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of locomotion of a cell or organism. + down regulation of locomotion + down-regulation of locomotion + downregulation of locomotion + inhibition of locomotion + biological_process + GO:0040013 + negative regulation of locomotion + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of locomotion of a cell or organism. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size. + regulation of body growth + regulation of body size + biological_process + GO:0040014 + regulation of multicellular organism growth + + + + + Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size. + GOC:dph + GOC:ems + GOC:tb + + + + + regulation of body growth + GOC:dph + GOC:tb + + + + + regulation of body size + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organism to reach its usual body size. + negative regulation of body growth + negative regulation of body size + biological_process + GO:0040015 + negative regulation of multicellular organism growth + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organism to reach its usual body size. + GOC:dph + GOC:ems + GOC:tb + + + + + negative regulation of body growth + GOC:dph + GOC:tb + + + + + negative regulation of body size + GOC:dph + GOC:tb + + + + + + + + + + + + + + + The first few specialized divisions of an activated animal egg. + biological_process + GO:0040016 + embryonic cleavage + + + + + The first few specialized divisions of an activated animal egg. + GOC:clt + ISBN:0070524300 + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism. + up regulation of locomotion + up-regulation of locomotion + upregulation of locomotion + activation of locomotion + stimulation of locomotion + biological_process + GO:0040017 + positive regulation of locomotion + + + + + Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size. + positive regulation of body growth + positive regulation of body size + biological_process + GO:0040018 + positive regulation of multicellular organism growth + + + + + Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size. + GOC:dph + GOC:go_curators + GOC:tb + + + + + positive regulation of body growth + GOC:dph + GOC:tb + + + + + positive regulation of body size + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of embryonic development. + up regulation of embryonic development + up-regulation of embryonic development + upregulation of embryonic development + activation of embryonic development + stimulation of embryonic development + biological_process + GO:0040019 + positive regulation of embryonic development + + + + + Any process that activates or increases the frequency, rate or extent of embryonic development. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of meiotic nuclear division, the process in which the nucleus of a diploid cell divides twice forming four haploid cells, one or more of which usually function as gametes. + regulation of meiosis + biological_process + GO:0040020 + regulation of meiotic nuclear division + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate or extent of meiotic nuclear division, the process in which the nucleus of a diploid cell divides twice forming four haploid cells, one or more of which usually function as gametes. + GOC:ems + GOC:ma + + + + + regulation of meiosis + GOC:vw + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the hermaphrodite genitalia over time, from formation to the mature structures. + biological_process + GO:0040035 + hermaphrodite genitalia development + + + + + The process whose specific outcome is the progression of the hermaphrodite genitalia over time, from formation to the mature structures. + GOC:ems + ISBN:0140512888 + + + + + + + + + The directed movement of substances that are in liquid form in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + biological_process + GO:0042044 + + fluid transport + + + + + The directed movement of substances that are in liquid form in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:ai + + + + + + + + + The behavior of an organism in response to an odor. + behavioral response to scent + behavioral response to smell + behavioural response to odour + behavioural response to scent + behavioural response to smell + olfactory behaviour + biological_process + GO:0042048 + olfactory behavior + + + + + The behavior of an organism in response to an odor. + GOC:jid + GOC:pr + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving dopamine. + regulation of dopamine metabolism + biological_process + GO:0042053 + regulation of dopamine metabolic process + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving dopamine. + GOC:go_curators + + + + + + + + + + + + + + + The series of events that restore integrity to a damaged tissue, following an injury. + Wikipedia:Wound_healing + biological_process + GO:0042060 + + wound healing + + + + + The series of events that restore integrity to a damaged tissue, following an injury. + GOC:bf + PMID:15269788 + + + + + + + + + + + + + + + + + + + + The process that results in the generation of glial cells. This includes the production of glial progenitors and their differentiation into mature glia. + glial cell generation + biological_process + GO:0042063 + gliogenesis + + + + + The process that results in the generation of glial cells. This includes the production of glial progenitors and their differentiation into mature glia. + GOC:dgh + GOC:jid + + + + + glial cell generation + + + + + + + + + + + + + + + + + + + + + + + + + + + Growth of glial cells, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system. + biological_process + GO:0042065 + glial cell growth + + + + + Growth of glial cells, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system. + GOC:dph + GOC:isa_complete + GOC:jid + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catecholamines. + regulation of catecholamine metabolism + biological_process + GO:0042069 + regulation of catecholamine metabolic process + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catecholamines. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The bidirectional movement of large protein complexes along microtubules within a cilium, mediated by motor proteins. + + + + + + + GO:0035734 + Wikipedia:Intraflagellar_transport + intraflagellar transport + intraflagellar transport involved in cilium organization + intraflagellar transport involved in microtubule-based flagellum organisation + biological_process + IFT + GO:0042073 + Note that we deem cilium and microtubule-based flagellum to be equivalent. + intraciliary transport + + + + + The bidirectional movement of large protein complexes along microtubules within a cilium, mediated by motor proteins. + GOC:cilia + GOC:kmv + PMID:17981739 + PMID:18180368 + PMID:22869374 + Reactome:R-HSA-5620924.2 + + + + + + + + + + + + + + + + + + + + The migration of individual cells within the blastocyst to help establish the multi-layered body plan of the organism (gastrulation). For example, the migration of cells from the surface to the interior of the embryo (ingression). + biological_process + GO:0042074 + cell migration involved in gastrulation + + + + + The migration of individual cells within the blastocyst to help establish the multi-layered body plan of the organism (gastrulation). For example, the migration of cells from the surface to the interior of the embryo (ingression). + GOC:jl + ISBN:0878932437 + http://www.cellmigration.org/ + + + + + + + + + + + + + + + + + + + + + The expansion of a T cell population by cell division. Follows T cell activation. + GO:0042111 + T lymphocyte proliferation + T-cell proliferation + T-lymphocyte proliferation + biological_process + GO:0042098 + T cell proliferation + + + + + The expansion of a T cell population by cell division. Follows T cell activation. + GOC:jl + + + + + + + + + + + + + + + + + + + + + The expansion of a B cell population by cell division. Follows B cell activation. + GO:0042114 + B lymphocyte proliferation + B-cell proliferation + B-lymphocyte proliferation + biological_process + GO:0042100 + B cell proliferation + + + + + The expansion of a B cell population by cell division. Follows B cell activation. + GOC:jl + + + + + + + + + + + + + + + + + + + Any process that activates or increases the rate or extent of T cell proliferation. + positive regulation of T lymphocyte proliferation + positive regulation of T-lymphocyte proliferation + up regulation of T cell proliferation + up-regulation of T cell proliferation + upregulation of T cell proliferation + activation of T cell proliferation + stimulation of T cell proliferation + biological_process + GO:0042102 + positive regulation of T cell proliferation + + + + + Any process that activates or increases the rate or extent of T cell proliferation. + GOC:ai + + + + + + + + + + + + + + + + + + + Any process that activates or increases the rate or extent of resting T cell proliferation. + positive regulation of T lymphocyte homeostatic proliferation + positive regulation of T-cell homeostatic proliferation + positive regulation of T-lymphocyte homeostatic proliferation + positive regulation of resting T cell proliferation + up regulation of T cell homeostatic proliferation + up-regulation of T cell homeostatic proliferation + upregulation of T cell homeostatic proliferation + activation of T cell homeostatic proliferation + stimulation of T cell homeostatic proliferation + biological_process + GO:0042103 + positive regulation of T cell homeostatic proliferation + + + + + Any process that activates or increases the rate or extent of resting T cell proliferation. + GOC:jl + + + + + + + + + + + + + + + + + + + + The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. + T lymphocyte activation + T-cell activation + T-lymphocyte activation + biological_process + GO:0042110 + T cell activation + + + + + The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. + GOC:mgi_curators + ISBN:0781735149 + + + + + + + + + + + + + + + + + + + + The change in morphology and behavior of a mature or immature B cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. + B lymphocyte activation + B-cell activation + B-lymphocyte activation + biological_process + GO:0042113 + B cell activation + + + + + The change in morphology and behavior of a mature or immature B cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific. + GOC:mgi_curators + ISBN:0781735149 + + + + + + + + + + + + + + + + + + + + A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. + macrophage polarization + biological_process + GO:0042116 + macrophage activation + + + + + A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. + GOC:mgi_curators + ISBN:0781735149 + PMID:14506301 + + + + + + + + + + + + + + + + + + + + The change in morphology and behavior of an endothelial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. + biological_process + GO:0042118 + endothelial cell activation + + + + + The change in morphology and behavior of an endothelial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. + GOC:mgi_curators + ISBN:0781735149 + PMID:12851652 + PMID:14581484 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of cell proliferation. + + biological_process + regulation of cell proliferation + GO:0042127 + regulation of cell population proliferation + + + + + Any process that modulates the frequency, rate or extent of cell proliferation. + GOC:jl + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of T cell proliferation. + regulation of T lymphocyte proliferation + regulation of T-cell proliferation + regulation of T-lymphocyte proliferation + biological_process + GO:0042129 + regulation of T cell proliferation + + + + + Any process that modulates the frequency, rate or extent of T cell proliferation. + GOC:jl + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the rate or extent of T cell proliferation. + down regulation of T cell proliferation + down-regulation of T cell proliferation + downregulation of T cell proliferation + negative regulation of T lymphocyte proliferation + negative regulation of T-cell proliferation + negative regulation of T-lymphocyte proliferation + inhibition of T cell proliferation + biological_process + GO:0042130 + negative regulation of T cell proliferation + + + + + Any process that stops, prevents or reduces the rate or extent of T cell proliferation. + GOC:jl + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways involving neurotransmitters, any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. + + neurotransmitter metabolism + biological_process + GO:0042133 + + neurotransmitter metabolic process + + + + + The chemical reactions and pathways involving neurotransmitters, any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. + GOC:jl + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. + neurotransmitter breakdown + neurotransmitter catabolism + neurotransmitter degradation + biological_process + GO:0042135 + + neurotransmitter catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. + GOC:jl + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. + neurotransmitter biosynthesis and storage + neurotransmitter biosynthetic process and storage + neurotransmitter anabolism + neurotransmitter biosynthesis + neurotransmitter formation + neurotransmitter synthesis + biological_process + GO:0042136 + + neurotransmitter biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. + GOC:jl + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways involving any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids. + lipoprotein metabolism + biological_process + GO:0042157 + lipoprotein metabolic process + + + + + The chemical reactions and pathways involving any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids. + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids. + lipoprotein anabolism + lipoprotein biosynthesis + lipoprotein formation + lipoprotein synthesis + biological_process + GO:0042158 + + lipoprotein biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids. + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids. + lipoprotein breakdown + lipoprotein catabolism + lipoprotein degradation + biological_process + GO:0042159 + lipoprotein catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of any conjugated, water-soluble protein in which the covalently attached nonprotein group consists of a lipid or lipids. + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + Binding to a neurotransmitter, any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell. + molecular_function + GO:0042165 + + neurotransmitter binding + + + + + Binding to a neurotransmitter, any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell. + ISBN:0198506732 + + + + + + + + + + + + + + + The continuous network of membranes encompassing the nuclear outer membrane and the endoplasmic reticulum membrane. + nuclear membrane-ER network + nuclear membrane-endoplasmic reticulum continuum + cellular_component + NE-ER continuum + NE-ER network + nuclear envelope-ER network + nuclear envelope-endoplasmic reticulum continuum + nuclear envelope-endoplasmic reticulum network + GO:0042175 + nuclear outer membrane-endoplasmic reticulum membrane network + + + + + The continuous network of membranes encompassing the nuclear outer membrane and the endoplasmic reticulum membrane. + GOC:bf + GOC:jl + GOC:mah + GOC:mcc + GOC:pr + GOC:vw + + + + + nuclear membrane-ER network + GOC:mah + + + + + nuclear membrane-endoplasmic reticulum continuum + GOC:mah + + + + + nuclear envelope-endoplasmic reticulum network + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. + https://github.com/geneontology/go-ontology/issues/23112 + kmv + 2014-08-21T15:05:45Z + GO:1903362 + GO:2000598 + regulation of cellular protein breakdown + regulation of cellular protein catabolic process + regulation of cellular protein catabolism + regulation of cellular protein degradation + regulation of protein breakdown + regulation of protein catabolism + regulation of protein degradation + regulation of cyclin breakdown + regulation of cyclin catabolic process + regulation of cyclin catabolism + regulation of cyclin degradation + regulation of degradation of cyclin + biological_process + GO:0042176 + regulation of protein catabolic process + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. + GOC:go_curators + GOC:jl + + + + + regulation of cellular protein breakdown + GOC:TermGenie + + + + + regulation of cellular protein catabolism + GOC:TermGenie + + + + + regulation of cellular protein degradation + GOC:TermGenie + + + + + regulation of cyclin breakdown + GOC:obol + + + + + regulation of cyclin catabolism + GOC:obol + + + + + regulation of cyclin degradation + GOC:obol + + + + + regulation of degradation of cyclin + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process. + https://github.com/geneontology/go-ontology/issues/23112 + GO:1903363 + GO:2000599 + down regulation of cellular protein breakdown + down regulation of cellular protein catabolic process + down regulation of cellular protein catabolism + down regulation of cellular protein degradation + down regulation of protein catabolic process + down-regulation of cellular protein breakdown + down-regulation of cellular protein catabolic process + down-regulation of cellular protein catabolism + down-regulation of cellular protein degradation + down-regulation of protein catabolic process + downregulation of cellular protein breakdown + downregulation of cellular protein catabolic process + downregulation of cellular protein catabolism + downregulation of cellular protein degradation + downregulation of protein catabolic process + negative regulation of cellular protein breakdown + negative regulation of cellular protein catabolic process + negative regulation of cellular protein catabolism + negative regulation of cellular protein degradation + negative regulation of protein breakdown + negative regulation of protein catabolism + negative regulation of protein degradation + inhibition of cellular protein breakdown + inhibition of cellular protein catabolic process + inhibition of cellular protein catabolism + inhibition of cellular protein degradation + inhibition of protein catabolic process + biological_process + GO:0042177 + negative regulation of protein catabolic process + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process. + GOC:TermGenie + GOC:kmv + GOC:obol + GO_REF:0000058 + PMID:24785082 + + + + + down regulation of cellular protein breakdown + GOC:TermGenie + + + + + down regulation of cellular protein catabolic process + GOC:TermGenie + + + + + down regulation of cellular protein catabolism + GOC:TermGenie + + + + + down regulation of cellular protein degradation + GOC:TermGenie + + + + + down-regulation of cellular protein breakdown + GOC:TermGenie + + + + + down-regulation of cellular protein catabolic process + GOC:TermGenie + + + + + down-regulation of cellular protein catabolism + GOC:TermGenie + + + + + down-regulation of cellular protein degradation + GOC:TermGenie + + + + + downregulation of cellular protein breakdown + GOC:TermGenie + + + + + downregulation of cellular protein catabolic process + GOC:TermGenie + + + + + downregulation of cellular protein catabolism + GOC:TermGenie + + + + + downregulation of cellular protein degradation + GOC:TermGenie + + + + + negative regulation of cellular protein breakdown + GOC:TermGenie + + + + + negative regulation of cellular protein catabolism + GOC:TermGenie + + + + + negative regulation of cellular protein degradation + GOC:TermGenie + + + + + inhibition of cellular protein breakdown + GOC:TermGenie + + + + + inhibition of cellular protein catabolic process + GOC:TermGenie + + + + + inhibition of cellular protein catabolism + GOC:TermGenie + + + + + inhibition of cellular protein degradation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups. + ketone metabolism + biological_process + GO:0042180 + + cellular ketone metabolic process + + + + + The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups. + GOC:jl + ISBN:0787650153 + + + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups. + ketone anabolism + ketone biosynthesis + ketone formation + ketone synthesis + biological_process + GO:0042181 + ketone biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups. + ketone breakdown + ketone catabolism + ketone degradation + biological_process + GO:0042182 + ketone catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups. + GOC:go_curators + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of compounds derived from amino acids, organic acids containing one or more amino substituents. + amino acid derivative catabolic process + cellular amino acid derivative breakdown + cellular amino acid derivative catabolic process + cellular amino acid derivative catabolism + cellular amino acid derivative degradation + cellular modified amino acid breakdown + cellular modified amino acid catabolism + cellular modified amino acid degradation + modified amino acid catabolic process + modified amino acid catabolism + biological_process + GO:0042219 + cellular modified amino acid catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of compounds derived from amino acids, organic acids containing one or more amino substituents. + GOC:ai + + + + + cellular modified amino acid breakdown + GOC:mah + + + + + cellular modified amino acid catabolism + GOC:mah + + + + + cellular modified amino acid degradation + GOC:mah + + + + + modified amino acid catabolic process + GOC:mah + + + + + modified amino acid catabolism + GOC:mah + + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus. + response to chemical stimulus + response to chemical substance + biological_process + GO:0042221 + + + + + + + Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. + response to chemical + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus. + GOC:jl + + + + + response to chemical stimulus + GOC:dos + + + + + + + + + + + + + + + + + + + + + The regrowth of lost or destroyed tissues. + biological_process + GO:0042246 + tissue regeneration + + + + + The regrowth of lost or destroyed tissues. + GOC:curators + + + + + + + + + + + + + + + + + + + Binding to a peptide, an organic compound comprising two or more amino acids linked by peptide bonds. + molecular_function + GO:0042277 + + + peptide binding + + + + + Binding to a peptide, an organic compound comprising two or more amino acids linked by peptide bonds. + GOC:jl + + + + + + + + + The periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin, etc. + biological_process + GO:0042303 + + + molting cycle + + + + + The periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin, etc. + GOC:jl + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the duration or quality of sleep, a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals. + down regulation of circadian sleep/wake cycle, sleep + down-regulation of circadian sleep/wake cycle, sleep + downregulation of circadian sleep/wake cycle, sleep + negative regulation of sleep + inhibition of circadian sleep/wake cycle, sleep + biological_process + GO:0042321 + negative regulation of circadian sleep/wake cycle, sleep + + + + + Any process that stops, prevents or reduces the duration or quality of sleep, a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals. + GOC:go_curators + GOC:jl + ISBN:0192800981 + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the duration or quality of non-rapid eye movement (NREM) sleep. + down regulation of circadian sleep/wake cycle, non-REM sleep + down-regulation of circadian sleep/wake cycle, non-REM sleep + downregulation of circadian sleep/wake cycle, non-REM sleep + negative regulation of non-REM sleep + inhibition of circadian sleep/wake cycle, non-REM sleep + biological_process + GO:0042323 + negative regulation of circadian sleep/wake cycle, non-REM sleep + + + + + Any process that stops, prevents or reduces the duration or quality of non-rapid eye movement (NREM) sleep. + GOC:jl + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule. + biological_process + GO:0042325 + regulation of phosphorylation + + + + + Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule. + GOC:jl + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule. + down regulation of phosphorylation + down-regulation of phosphorylation + downregulation of phosphorylation + inhibition of phosphorylation + biological_process + GO:0042326 + negative regulation of phosphorylation + + + + + Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule. + GOC:jl + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule. + up regulation of phosphorylation + up-regulation of phosphorylation + upregulation of phosphorylation + activation of phosphorylation + stimulation of phosphorylation + biological_process + GO:0042327 + positive regulation of phosphorylation + + + + + Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule. + GOC:jl + + + + + + + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of a cuticle, the outer layer of some animals and plants, which acts to prevent water loss. + cuticle anabolism + cuticle biosynthesis + cuticle biosynthetic process + cuticle formation + cuticle synthesis + biological_process + GO:0042335 + + cuticle development + + + + + The chemical reactions and pathways resulting in the formation of a cuticle, the outer layer of some animals and plants, which acts to prevent water loss. + ISBN:0192800825 + + + + + + + + + + + + + + + + + + + + The synthesis and deposition of a chitin-based non-cellular, hardened, or membranous secretion from an epithelial sheet, occurring as part of the molting cycle. An example of this is found in Drosophila melanogaster. + cuticle anabolism during molting + cuticle biosynthetic process during molting + cuticle formation during molting + cuticle synthesis during molting + biological_process + chitin-based cuticle development during molting + GO:0042337 + cuticle development involved in chitin-based cuticle molting cycle + + + + + The synthesis and deposition of a chitin-based non-cellular, hardened, or membranous secretion from an epithelial sheet, occurring as part of the molting cycle. An example of this is found in Drosophila melanogaster. + GOC:dph + GOC:jl + GOC:mtg_sensu + GOC:tb + + + + + chitin-based cuticle development during molting + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways involving keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues. + keratan sulfate metabolism + keratan sulphate metabolic process + keratan sulphate metabolism + biological_process + GO:0042339 + keratan sulfate metabolic process + + + + + The chemical reactions and pathways involving keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues. + GOC:go_curators + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues. + keratan sulfate breakdown + keratan sulfate catabolism + keratan sulfate degradation + keratan sulphate catabolic process + keratan sulphate catabolism + biological_process + GO:0042340 + keratan sulfate catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires the characteristics of a mature hemocyte. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. + arthropod blood cell differentiation + biological_process + GO:0042386 + hemocyte differentiation + + + + + The process in which a relatively unspecialized cell acquires the characteristics of a mature hemocyte. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. + CL:0000387 + GOC:jl + GOC:mtg_sensu + PMID:9550723 + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of compounds derived from amino acids, organic acids containing one or more amino substituents. + amino acid derivative biosynthetic process + cellular amino acid derivative anabolism + cellular amino acid derivative biosynthesis + cellular amino acid derivative biosynthetic process + cellular amino acid derivative formation + cellular amino acid derivative synthesis + cellular modified amino acid anabolism + cellular modified amino acid biosynthesis + cellular modified amino acid formation + cellular modified amino acid synthesis + biological_process + GO:0042398 + cellular modified amino acid biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of compounds derived from amino acids, organic acids containing one or more amino substituents. + GOC:ai + + + + + cellular modified amino acid anabolism + GOC:mah + + + + + cellular modified amino acid biosynthesis + GOC:mah + + + + + cellular modified amino acid formation + GOC:mah + + + + + cellular modified amino acid synthesis + GOC:mah + + + + + + + + + + The chemical reactions and pathways occurring at the level of individual cells resulting in the formation of any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters. + biogenic amine anabolism + biogenic amine biosynthesis + biogenic amine formation + biogenic amine synthesis + biological_process + GO:0042401 + cellular biogenic amine biosynthetic process + + + + + The chemical reactions and pathways occurring at the level of individual cells resulting in the formation of any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters. + GOC:jl + ISBN:0395825172 + + + + + + + + + The chemical reactions and pathways occurring at the level of individual cells resulting in the breakdown of biogenic amines, any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters. + biogenic amine breakdown + biogenic amine catabolism + biogenic amine degradation + biological_process + GO:0042402 + cellular biogenic amine catabolic process + + + + + The chemical reactions and pathways occurring at the level of individual cells resulting in the breakdown of biogenic amines, any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters. + GOC:go_curators + GOC:jl + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways involving any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine. + thyroid hormone metabolism + biological_process + GO:0042403 + thyroid hormone metabolic process + + + + + The chemical reactions and pathways involving any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine. + GOC:jl + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine. + thyroid hormone breakdown + thyroid hormone catabolism + thyroid hormone degradation + biological_process + GO:0042404 + thyroid hormone catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine. + GOC:jl + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways involving norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine. + levarterenol metabolic process + levarterenol metabolism + noradrenaline metabolic process + noradrenaline metabolism + norepinephrine metabolism + biological_process + GO:0042415 + norepinephrine metabolic process + + + + + The chemical reactions and pathways involving norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine. + GOC:jl + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline. + dopamine anabolism + dopamine biosynthesis + dopamine formation + dopamine synthesis + biological_process + GO:0042416 + dopamine biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline. + GOC:jl + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline. + dopamine metabolism + biological_process + GO:0042417 + dopamine metabolic process + + + + + The chemical reactions and pathways involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline. + GOC:jl + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline. + dopamine breakdown + dopamine catabolism + dopamine degradation + biological_process + GO:0042420 + dopamine catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline. + GOC:jl + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine. + levarterenol biosynthesis + levarterenol biosynthetic process + noradrenaline biosynthesis + noradrenaline biosynthetic process + norepinephrine anabolism + norepinephrine biosynthesis + norepinephrine formation + norepinephrine synthesis + biological_process + GO:0042421 + norepinephrine biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine. + GOC:jl + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine. + Wikipedia:Norepinephrine#Degradation + levarterenol catabolic process + levarterenol catabolism + noradrenaline catabolic process + noradrenaline catabolism + norepinephrine breakdown + norepinephrine catabolism + norepinephrine degradation + biological_process + GO:0042422 + norepinephrine catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine. + GOC:jl + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. + Wikipedia:Catecholamines + catecholamine anabolism + catecholamine biosynthesis + catecholamine formation + catecholamine synthesis + biological_process + GO:0042423 + catecholamine biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. + GOC:jl + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. + catecholamine breakdown + catecholamine catabolism + catecholamine degradation + biological_process + GO:0042424 + catecholamine catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. + GOC:jl + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine. + MetaCyc:PWY-4762 + choline anabolism + choline biosynthesis + choline formation + choline synthesis + biological_process + GO:0042425 + choline biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine. + GOC:jl + ISBN:0192801023 + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine. + choline breakdown + choline catabolism + choline degradation + biological_process + GO:0042426 + choline catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine. + GOC:jl + ISBN:0192801023 + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties. + Wikipedia:Serotonin + serotonin anabolism + serotonin biosynthesis + serotonin formation + serotonin synthesis + biological_process + GO:0042427 + serotonin biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties. + GOC:jl + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways involving serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties. + serotonin metabolism + biological_process + GO:0042428 + serotonin metabolic process + + + + + The chemical reactions and pathways involving serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties. + GOC:jl + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties. + serotonin breakdown + serotonin catabolism + serotonin degradation + biological_process + GO:0042429 + serotonin catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties. + GOC:jl + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways involving compounds that contain an indole (2,3-benzopyrrole) skeleton. + GO:0042434 + indole and derivative metabolic process + indole and derivative metabolism + indole-containing compound metabolism + ketole metabolic process + ketole metabolism + indole derivative metabolic process + indole derivative metabolism + biological_process + GO:0042430 + indole-containing compound metabolic process + + + + + The chemical reactions and pathways involving compounds that contain an indole (2,3-benzopyrrole) skeleton. + GOC:jl + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of compounds that contain an indole (2,3-benzopyrrole) skeleton. + indole derivative biosynthesis + indole derivative biosynthetic process + indole-containing compound anabolism + indole-containing compound biosynthesis + indole-containing compound formation + indole-containing compound synthesis + biological_process + GO:0042435 + indole-containing compound biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of compounds that contain an indole (2,3-benzopyrrole) skeleton. + GOC:jl + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of compounds that contain an indole (2,3-benzopyrrole) skeleton. + indole derivative catabolic process + indole derivative catabolism + indole-containing compound breakdown + indole-containing compound catabolism + indole-containing compound degradation + biological_process + GO:0042436 + indole-containing compound catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of compounds that contain an indole (2,3-benzopyrrole) skeleton. + GOC:jl + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of melatonin (N-acetyl-5-methoxytryptamine). + GO:0042449 + melatonin breakdown + melatonin catabolism + melatonin degradation + biological_process + GO:0042442 + melatonin catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of melatonin (N-acetyl-5-methoxytryptamine). + GOC:jl + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways involving any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone. + + hormone metabolism + biological_process + GO:0042445 + + hormone metabolic process + + + + + The chemical reactions and pathways involving any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone. + GOC:jl + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone. + hormone anabolism + hormone biosynthesis + hormone formation + hormone synthesis + biological_process + GO:0042446 + hormone biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone. + GOC:jl + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone. + hormone breakdown + hormone catabolism + hormone degradation + biological_process + GO:0042447 + hormone catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone. + GOC:jl + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways involving progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants. + progesterone metabolism + biological_process + GO:0042448 + progesterone metabolic process + + + + + The chemical reactions and pathways involving progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants. + GOC:jl + http://www.cogsci.princeton.edu/ + + + + + + + + + + + + + + + + + + + + + + + + + + Development of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light. + GO:0046531 + photoreceptor morphogenesis + biological_process + GO:0042461 + photoreceptor cell development + + + + + Development of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + + + + + Development of a photoreceptor, a sensory cell in the eye that reacts to the presence of light. They usually contain a pigment that undergoes a chemical change when light is absorbed, thus stimulating a nerve. + biological_process + GO:0042462 + eye photoreceptor cell development + + + + + Development of a photoreceptor, a sensory cell in the eye that reacts to the presence of light. They usually contain a pigment that undergoes a chemical change when light is absorbed, thus stimulating a nerve. + GOC:jl + ISBN:0192800981 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the ear are generated and organized. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals. + hearing organ morphogenesis + biological_process + GO:0042471 + ear morphogenesis + + + + + The process in which the anatomical structures of the ear are generated and organized. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals. + GOC:jl + ISBN:0192801023 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the inner ear are generated and organized. The inner ear is the structure in vertebrates that contains the organs of balance and hearing. It consists of soft hollow sensory structures (the membranous labyrinth) containing fluid (endolymph) surrounded by fluid (perilymph) and encased in a bony cavity (the bony labyrinth). It consists of two chambers, the sacculus and utriculus, from which arise the cochlea and semicircular canals respectively. + biological_process + GO:0042472 + inner ear morphogenesis + + + + + The process in which the anatomical structures of the inner ear are generated and organized. The inner ear is the structure in vertebrates that contains the organs of balance and hearing. It consists of soft hollow sensory structures (the membranous labyrinth) containing fluid (endolymph) surrounded by fluid (perilymph) and encased in a bony cavity (the bony labyrinth). It consists of two chambers, the sacculus and utriculus, from which arise the cochlea and semicircular canals respectively. + GOC:jl + ISBN:0192801023 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the outer ear are generated and organized. The outer ear is the part of the ear external to the tympanum (eardrum). It consists of a tube (the external auditory meatus) that directs sound waves on to the tympanum, and may also include the external pinna, which extends beyond the skull. + biological_process + GO:0042473 + outer ear morphogenesis + + + + + The process in which the anatomical structures of the outer ear are generated and organized. The outer ear is the part of the ear external to the tympanum (eardrum). It consists of a tube (the external auditory meatus) that directs sound waves on to the tympanum, and may also include the external pinna, which extends beyond the skull. + GOC:jl + ISBN:0192801023 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the middle ear are generated and organized. The middle ear is the air-filled cavity within the skull of vertebrates that lies between the outer ear and the inner ear. It is linked to the pharynx (and therefore to outside air) via the Eustachian tube and in mammals contains the three ear ossicles, which transmit auditory vibrations from the outer ear (via the tympanum) to the inner ear (via the oval window). + biological_process + GO:0042474 + middle ear morphogenesis + + + + + The process in which the anatomical structures of the middle ear are generated and organized. The middle ear is the air-filled cavity within the skull of vertebrates that lies between the outer ear and the inner ear. It is linked to the pharynx (and therefore to outside air) via the Eustachian tube and in mammals contains the three ear ossicles, which transmit auditory vibrations from the outer ear (via the tympanum) to the inner ear (via the oval window). + GOC:jl + ISBN:0192801023 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a dentin-containing tooth over time, from its formation to the mature structure. A dentin-containing tooth is a hard, bony organ borne on the jaw or other bone of a vertebrate, and is composed mainly of dentin, a dense calcified substance, covered by a layer of enamel. + odontogeny + odontosis + tooth development + odontogenesis of dentine-containing teeth + odontogenesis of dentine-containing tooth + biological_process + GO:0042475 + Note that placoid scales found in the cartilaginous fishes presumably develop through the same processes, but are found on the dermis, rather than in the mouth or pharynx. See Wikipedia:Placoid_scale#Placoid_scales. + odontogenesis of dentin-containing tooth + + + + + The process whose specific outcome is the progression of a dentin-containing tooth over time, from its formation to the mature structure. A dentin-containing tooth is a hard, bony organ borne on the jaw or other bone of a vertebrate, and is composed mainly of dentin, a dense calcified substance, covered by a layer of enamel. + GOC:cjm + GOC:mah + GOC:mtg_sensu + PMID:10333884 + PMID:15355794 + + + + + odontogenesis of dentine-containing tooth + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a tooth or teeth over time, from formation to the mature structure(s). A tooth is any hard bony, calcareous, or chitinous organ found in the mouth or pharynx of an animal and used in procuring or masticating food. + + GO:0042477 + Wikipedia:Odontogenesis + odontogeny + odontosis + tooth morphogenesis + odontogenesis of calcareous or chitinous tooth + biological_process + tooth development + GO:0042476 + odontogenesis + + + + + The process whose specific outcome is the progression of a tooth or teeth over time, from formation to the mature structure(s). A tooth is any hard bony, calcareous, or chitinous organ found in the mouth or pharynx of an animal and used in procuring or masticating food. + GOC:jl + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of eye photoreceptor development. + regulation of eye photoreceptor development + biological_process + GO:0042478 + regulation of eye photoreceptor cell development + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate or extent of eye photoreceptor development. + GOC:jl + + + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of eye photoreceptor development. + positive regulation of eye photoreceptor development + up regulation of eye photoreceptor cell development + up-regulation of eye photoreceptor cell development + upregulation of eye photoreceptor cell development + activation of eye photoreceptor cell development + stimulation of eye photoreceptor cell development + biological_process + GO:0042479 + positive regulation of eye photoreceptor cell development + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that activates or increases the frequency, rate or extent of eye photoreceptor development. + GOC:jl + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of eye photoreceptor development. + down regulation of eye photoreceptor cell development + down-regulation of eye photoreceptor cell development + downregulation of eye photoreceptor cell development + negative regulation of eye photoreceptor development + inhibition of eye photoreceptor cell development + biological_process + GO:0042480 + negative regulation of eye photoreceptor cell development + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of eye photoreceptor development. + GOC:jl + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the formation and development of a tooth or teeth. + GO:0042484 + regulation of tooth development + regulation of odontogenesis of calcareous or chitinous tooth + biological_process + GO:0042481 + regulation of odontogenesis + + + + + Any process that modulates the frequency, rate or extent of the formation and development of a tooth or teeth. + GOC:jl + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the formation and development of a tooth or teeth. + GO:0042485 + positive regulation of tooth development + up regulation of odontogenesis + up-regulation of odontogenesis + upregulation of odontogenesis + activation of odontogenesis + positive regulation of odontogenesis of calcareous or chitinous tooth + stimulation of odontogenesis + biological_process + GO:0042482 + positive regulation of odontogenesis + + + + + Any process that activates or increases the frequency, rate or extent of the formation and development of a tooth or teeth. + GOC:jl + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the formation and development of a tooth or teeth. + GO:0042486 + down regulation of odontogenesis + down-regulation of odontogenesis + downregulation of odontogenesis + negative regulation of tooth development + inhibition of odontogenesis + negative regulation of odontogenesis of calcareous or chitinous tooth + biological_process + GO:0042483 + negative regulation of odontogenesis + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the formation and development of a tooth or teeth. + GOC:jl + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx of most vertebrates. + regulation of odontogenesis of dentine-containing teeth + regulation of odontogenesis of dentine-containing tooth + biological_process + GO:0042487 + regulation of odontogenesis of dentin-containing tooth + + + + + Any process that modulates the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx of most vertebrates. + GOC:jl + GOC:mtg_sensu + PMID:15355794 + + + + + regulation of odontogenesis of dentine-containing tooth + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages that are borne on the jaws, or on other bones in the walls of the mouth or pharynx of most vertebrates. + activation of odontogenesis + stimulation of odontogenesis + up regulation of odontogenesis + up-regulation of odontogenesis + upregulation of odontogenesis + positive regulation of odontogenesis of dentine-containing teeth + biological_process + positive regulation of odontogenesis of dentine-containing tooth + GO:0042488 + positive regulation of odontogenesis of dentin-containing tooth + + + + + Any process that activates or increases the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages that are borne on the jaws, or on other bones in the walls of the mouth or pharynx of most vertebrates. + GOC:jl + PMID:15355794 + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx. + down regulation of odontogenesis + down-regulation of odontogenesis + downregulation of odontogenesis + inhibition of odontogenesis + negative regulation of odontogenesis + negative regulation of odontogenesis of dentine-containing teeth + biological_process + negative regulation of odontogenesis of dentine-containing tooth + GO:0042489 + negative regulation of odontogenesis of dentin-containing tooth + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx. + GOC:jl + GOC:mtg_sensu + PMID:15355794 + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of a mechanoreceptor, a cell specialized to transduce mechanical stimuli and relay that information centrally in the nervous system. + biological_process + GO:0042490 + mechanoreceptor differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized features of a mechanoreceptor, a cell specialized to transduce mechanical stimuli and relay that information centrally in the nervous system. + CL:0000199 + GOC:jl + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized inner cell acquires specialized features of an auditory hair cell. + auditory hair cell differentiation + biological_process + auditory receptor cell differentiation + GO:0042491 + Note that this term refers to the mechanosensory hair cells of the inner ear. + inner ear auditory receptor cell differentiation + + + + + The process in which a relatively unspecialized inner cell acquires specialized features of an auditory hair cell. + CL:0000201 + GOC:jl + + + + + + + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for a neuron to attain its fully functional state. + biological_process + GO:0042551 + neuron maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for a neuron to attain its fully functional state. + GOC:dph + GOC:jl + + + + + + + + + The process in which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier. + Wikipedia:Myelin + biological_process + myelinogenesis + GO:0042552 + myelination + + + + + The process in which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier. + GOC:dgh + GOC:mah + + + + + myelinogenesis + GOC:cjm + HP:0003429 + + + + + + + + + + + + + + + + + + + + Binding to an hormone, a naturally occurring substance secreted by specialized cells that affect the metabolism or behavior of cells possessing functional receptors for the hormone. Hormones may be produced by the same, or different, cell as express the receptor. + molecular_function + GO:0042562 + + + hormone binding + + + + + Binding to an hormone, a naturally occurring substance secreted by specialized cells that affect the metabolism or behavior of cells possessing functional receptors for the hormone. Hormones may be produced by the same, or different, cell as express the receptor. + GOC:jl + + + + + + + + + Any biological process involved in the maintenance of an internal steady state. + GO:0032844 + GO:0032845 + GO:0032846 + homeostasis + activation of homeostatic process + inhibition of homeostatic process + biological_process + negative regulation of homeostatic process + positive regulation of homeostatic process + regulation of homeostatic process + GO:0042592 + + + + homeostatic process + + + + + Any biological process involved in the maintenance of an internal steady state. + GOC:jl + ISBN:0395825172 + + + + + + + + + + + + + + + + + + + Any process involved in the maintenance of an internal steady state of glucose within an organism or cell. + biological_process + GO:0042593 + glucose homeostasis + + + + + Any process involved in the maintenance of an internal steady state of glucose within an organism or cell. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body. + + biological_process + GO:0042633 + hair cycle + + + + + The cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body. + GOC:go_curators + PMID:12230507 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair. + biological_process + GO:0042634 + regulation of hair cycle + + + + + Any process that modulates the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair. + GOC:go_curators + PMID:12230507 + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair. + up regulation of hair cycle + up-regulation of hair cycle + upregulation of hair cycle + activation of hair cycle + stimulation of hair cycle + biological_process + GO:0042635 + positive regulation of hair cycle + + + + + Any process that activates or increases the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair. + GOC:go_curators + PMID:12230507 + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair. + down regulation of hair cycle + down-regulation of hair cycle + downregulation of hair cycle + inhibition of hair cycle + biological_process + GO:0042636 + negative regulation of hair cycle + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair. + GOC:go_curators + PMID:12230507 + + + + + + + + + + + + + + + + + + + + + Any complex of actin, myosin, and accessory proteins. + actomyosin complex + actomyosin structure + cellular_component + GO:0042641 + actomyosin + + + + + Any complex of actin, myosin, and accessory proteins. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires the specialized features of a retinal cone cell. + biological_process + GO:0042670 + retinal cone cell differentiation + + + + + The process in which a relatively unspecialized cell acquires the specialized features of a retinal cone cell. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of a muscle cell. + biological_process + myogenesis + GO:0042692 + muscle cell differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized features of a muscle cell. + CL:0000187 + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + + The type of sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years. + biological_process + GO:0042698 + ovulation cycle + + + + + The type of sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years. + ISBN:0721662544 + + + + + + + + + + + + + + + + + + + + + + + + + + + + The regulated release of progesterone, a steroid hormone, by the corpus luteum of the ovary and by the placenta. + biological_process + GO:0042701 + progesterone secretion + + + + + The regulated release of progesterone, a steroid hormone, by the corpus luteum of the ovary and by the placenta. + GOC:jl + ISBN:0395825172 + + + + + + + + + + + + + + + + + + + + + + + + + + The regrowth of the endometrium and blood vessels in the uterus following menstruation, resulting from a rise in progesterone levels. + biological_process + GO:0042702 + uterine wall growth + + + + + The regrowth of the endometrium and blood vessels in the uterus following menstruation, resulting from a rise in progesterone levels. + GOC:jl + + + + + + + + + + + + + + + + The expulsion of seminal fluid, thick white fluid containing spermatozoa, from the male genital tract. + biological_process + GO:0042713 + sperm ejaculation + + + + + The expulsion of seminal fluid, thick white fluid containing spermatozoa, from the male genital tract. + GOC:jl + http://www.cogsci.princeton.edu/~wn/ + + + + + + + + + + + + + + + + + + + Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism. + GO:0009816 + GO:0042830 + defence response to bacteria + defence response to bacterium + defense response to bacteria + defense response to bacterium, incompatible interaction + resistance response to pathogenic bacteria + resistance response to pathogenic bacterium + biological_process + antibacterial peptide activity + GO:0042742 + defense response to bacterium + + + + + Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism. + GOC:jl + + + + + + + + + The cycle from wakefulness through an orderly succession of sleep states and stages that occurs on an approximately 24 hour rhythm. + biological_process + GO:0042745 + circadian sleep/wake cycle + + + + + The cycle from wakefulness through an orderly succession of sleep states and stages that occurs on an approximately 24 hour rhythm. + GOC:jl + http://www.sleepquest.com + + + + + + + + + + + + + + + All sleep stages in the circadian sleep/wake cycle other than REM sleep. These stages are characterized by a slowing of brain waves and other physiological functions. + biological_process + GO:0042748 + circadian sleep/wake cycle, non-REM sleep + + + + + All sleep stages in the circadian sleep/wake cycle other than REM sleep. These stages are characterized by a slowing of brain waves and other physiological functions. + GOC:jl + http://www.sleepquest.com + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the circadian sleep/wake cycle. + biological_process + GO:0042749 + regulation of circadian sleep/wake cycle + + + + + Any process that modulates the frequency, rate or extent of the circadian sleep/wake cycle. + GOC:jl + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of a circadian rhythm. A circadian rhythm is a biological process in an organism that recurs with a regularity of approximately 24 hours. + biological_process + GO:0042752 + regulation of circadian rhythm + + + + + Any process that modulates the frequency, rate or extent of a circadian rhythm. A circadian rhythm is a biological process in an organism that recurs with a regularity of approximately 24 hours. + GOC:dph + GOC:jl + GOC:tb + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of a circadian rhythm behavior. + up regulation of circadian rhythm + up-regulation of circadian rhythm + upregulation of circadian rhythm + activation of circadian rhythm + stimulation of circadian rhythm + biological_process + GO:0042753 + positive regulation of circadian rhythm + + + + + Any process that activates or increases the frequency, rate or extent of a circadian rhythm behavior. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of a circadian rhythm behavior. + down regulation of circadian rhythm + down-regulation of circadian rhythm + downregulation of circadian rhythm + inhibition of circadian rhythm + biological_process + GO:0042754 + negative regulation of circadian rhythm + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of a circadian rhythm behavior. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways involving pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process. + pheromone metabolism + biological_process + GO:0042810 + + pheromone metabolic process + + + + + The chemical reactions and pathways involving pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process. + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process. + pheromone anabolism + pheromone biosynthesis + pheromone formation + pheromone synthesis + biological_process + GO:0042811 + pheromone biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process. + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process. + GO:0007327 + GO:0046614 + pheromone breakdown + pheromone catabolism + pheromone degradation + biological_process + GO:0042812 + pheromone catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process. + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + The directed movement of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + biological_process + GO:0042886 + + amide transport + + + + + The directed movement of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:jl + ISBN:0198506732 + + + + + + + + + The series of molecular signals initiated by glucocorticoid binding to its receptor. + glucocorticoid receptor signalling pathway + biological_process + GO:0042921 + glucocorticoid receptor signaling pathway + + + + + The series of molecular signals initiated by glucocorticoid binding to its receptor. + GOC:mah + + + + + + + + + Interacting selectively and non-covalently and stoichiometrically with neuropeptides, peptides with direct synaptic effects (peptide neurotransmitters) or indirect modulatory effects on the nervous system (peptide neuromodulators). + molecular_function + GO:0042923 + neuropeptide binding + + + + + Interacting selectively and non-covalently and stoichiometrically with neuropeptides, peptides with direct synaptic effects (peptide neurotransmitters) or indirect modulatory effects on the nervous system (peptide neuromodulators). + http://www.wormbook.org/chapters/www_neuropeptides/neuropeptides.html + + + + + + + + + + + + + + + + + + + + The directed movement of any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + biological_process + GO:0042953 + lipoprotein transport + + + + + The directed movement of any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:jl + ISBN:0198506732 + + + + + + + + + + + + + + + A prolongation or process extending from a cell, e.g. a flagellum or axon. + cell process + cellular process + cellular projection + cellular_component + GO:0042995 + + + + + + cell projection + + + + + A prolongation or process extending from a cell, e.g. a flagellum or axon. + GOC:jl + http://www.cogsci.princeton.edu/~wn/ + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane. + biological_process + GO:0042996 + regulation of Golgi to plasma membrane protein transport + + + + + Any process that modulates the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane. + GOC:jl + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane. + down regulation of Golgi to plasma membrane protein transport + down-regulation of Golgi to plasma membrane protein transport + downregulation of Golgi to plasma membrane protein transport + inhibition of Golgi to plasma membrane protein transport + biological_process + GO:0042997 + negative regulation of Golgi to plasma membrane protein transport + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane. + GOC:jl + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane. + up regulation of Golgi to plasma membrane protein transport + up-regulation of Golgi to plasma membrane protein transport + upregulation of Golgi to plasma membrane protein transport + activation of Golgi to plasma membrane protein transport + stimulation of Golgi to plasma membrane protein transport + biological_process + GO:0042998 + positive regulation of Golgi to plasma membrane protein transport + + + + + Any process that activates or increases the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane. + GOC:jl + + + + + + + + + + + + + + + + + + + + + + + + + + + The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane. + biological_process + GO:0043001 + Golgi to plasma membrane protein transport + + + + + The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane. + ISBN:0716731363 + + + + + + + + + + + + + + + + + + + + + + + + + A prolongation or process extending from a nerve cell, e.g. an axon or dendrite. + NIF_Subcellular:sao867568886 + neuron process + neuron protrusion + neuronal cell projection + neurite + cellular_component + nerve fiber + GO:0043005 + + neuron projection + + + + + A prolongation or process extending from a nerve cell, e.g. an axon or dendrite. + GOC:jl + http://www.cogsci.princeton.edu/~wn/ + + + + + neuron protrusion + NIF_Subcellular:sao250931889 + + + + + nerve fiber + GOC:dph + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching. + biological_process + GO:0043009 + chordate embryonic development + + + + + The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching. + GOC:mtg_sensu + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field. + + GO:0001747 + GO:0031075 + biological_process + GO:0043010 + camera-type eye development + + + + + The process whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field. + GOC:go_curators + GOC:mtg_sensu + + + + + + + + + + + + + + + + + + + + + The process in which a monocyte acquires the specialized features of a dendritic cell, an immunocompetent cell of the lymphoid and hemopoietic systems and skin. + Wikipedia:Dendritic_cell + biological_process + GO:0043011 + myeloid dendritic cell differentiation + + + + + The process in which a monocyte acquires the specialized features of a dendritic cell, an immunocompetent cell of the lymphoid and hemopoietic systems and skin. + CL:0000782 + GOC:jl + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites. + NIF_Subcellular:sao1044911821 + Wikipedia:Soma_(biology) + neuron cell body + neuronal cell soma + cellular_component + GO:0043025 + + Note that 'cell body' and 'cell soma' are not used in the literature for cells that lack projections, nor for some cells (e.g. yeast with mating projections) that do have projections. + neuronal cell body + + + + + The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + The process of regulating the proliferation and elimination of T cells such that the total number of T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. + T lymphocyte homeostasis + T-cell homeostasis + T-lymphocyte homeostasis + biological_process + GO:0043029 + Note that this term represents the return of T cell levels to stable numbers following an immune response as well as the proliferation and elimination of T cells required to maintain stable numbers in the absence of an outside stimulus. + T cell homeostasis + + + + + The process of regulating the proliferation and elimination of T cells such that the total number of T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. + GOC:mgi_curators + ISBN:0781735149 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency or rate of macrophage activation. + regulation of macrophage polarization + biological_process + GO:0043030 + regulation of macrophage activation + + + + + Any process that modulates the frequency or rate of macrophage activation. + GOC:jl + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage activation. + down regulation of macrophage activation + down-regulation of macrophage activation + downregulation of macrophage activation + negative regulation of macrophage polarization + inhibition of macrophage activation + biological_process + GO:0043031 + negative regulation of macrophage activation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage activation. + GOC:jl + + + + + + + + + + + + + + + + + + + Any process that stimulates, induces or increases the rate of macrophage activation. + positive regulation of macrophage polarization + up regulation of macrophage activation + up-regulation of macrophage activation + upregulation of macrophage activation + activation of macrophage activation + stimulation of macrophage activation + biological_process + GO:0043032 + positive regulation of macrophage activation + + + + + Any process that stimulates, induces or increases the rate of macrophage activation. + GOC:jl + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. This may include the translation of a precursor protein and its subsequent processing into a functional peptide. + peptide anabolism + peptide biosynthesis + peptide formation + peptide synthesis + biological_process + GO:0043043 + peptide biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. This may include the translation of a precursor protein and its subsequent processing into a functional peptide. + GOC:dph + GOC:jl + + + + + + + + + + + + + + + + + + + + + + + + + + The initial developmental process that will lead to the formation of the vertebrate inner ear. The otic placode forms as a thickening of the head ectoderm adjacent to the developing hindbrain. + biological_process + GO:0043049 + otic placode formation + + + + + The initial developmental process that will lead to the formation of the vertebrate inner ear. The otic placode forms as a thickening of the head ectoderm adjacent to the developing hindbrain. + GOC:go_curators + PMID:12668634 + + + + + + + + + + + + + + + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures in the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane, and also covers the host cell environment outside an intracellular parasite. + extracellular structure organisation + extracellular structure organization and biogenesis + biological_process + GO:0043062 + + + extracellular structure organization + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures in the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane, and also covers the host cell environment outside an intracellular parasite. + GOC:ai + GOC:dph + GOC:jl + GOC:mah + + + + + extracellular structure organization and biogenesis + GOC:dph + GOC:jl + GOC:mah + + + + + + + + + + + + + + + + + + + + The nucleus of a germ cell, a reproductive cell in multicellular organisms. + germ-cell nucleus + cellular_component + GO:0043073 + germ cell nucleus + + + + + The nucleus of a germ cell, a reproductive cell in multicellular organisms. + CL:0000586 + GOC:go_curators + + + + + + + + + + + + + + + + The hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow. + Wikipedia:Erection#Penile_erection + biological_process + GO:0043084 + penile erection + + + + + The hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow. + GOC:jl + Wikipedia:Penile_erection + + + + + + + + + + + + + + + + + + + Any process that activates or increases the activity of an enzyme. + GO:0048554 + positive regulation of enzyme activity + up regulation of enzyme activity + up-regulation of enzyme activity + upregulation of enzyme activity + activation of enzyme activity + activation of metalloenzyme activity + positive regulation of metalloenzyme activity + stimulation of enzyme activity + stimulation of metalloenzyme activity + up regulation of metalloenzyme activity + up-regulation of metalloenzyme activity + upregulation of metalloenzyme activity + biological_process + GO:0043085 + + positive regulation of catalytic activity + + + + + Any process that activates or increases the activity of an enzyme. + GOC:ebc + GOC:jl + GOC:tb + GOC:vw + + + + + positive regulation of enzyme activity + GOC:tb + + + + + + + + + + + + + + + + + + + Any process that stops or reduces the activity of an enzyme. + GO:0048553 + down regulation of enzyme activity + down-regulation of enzyme activity + down-regulation of metalloenzyme activity + downregulation of enzyme activity + negative regulation of enzyme activity + down regulation of metalloenzyme activity + downregulation of metalloenzyme activity + inhibition of enzyme activity + inhibition of metalloenzyme activity + negative regulation of metalloenzyme activity + biological_process + GO:0043086 + negative regulation of catalytic activity + + + + + Any process that stops or reduces the activity of an enzyme. + GOC:ebc + GOC:jl + GOC:tb + GOC:vw + + + + + negative regulation of enzyme activity + GOC:tb + + + + + + + + + + + + + + + + + + + + + A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the hindgut. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The hindgut is the posterior part of the alimentary canal, including the rectum, and the large intestine. + biological_process + GO:0043133 + hindgut contraction + + + + + A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the hindgut. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The hindgut is the posterior part of the alimentary canal, including the rectum, and the large intestine. + GOC:jl + GOC:mtg_muscle + UBERON:0001046 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine. + biological_process + GO:0043134 + regulation of hindgut contraction + + + + + Any process that modulates the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine. + GOC:jl + UBERON:0001046 + + + + + + + + + + + + + + + + + + + Binding to an ion, a charged atoms or groups of atoms. + molecular_function + atom binding + GO:0043167 + + + + + ion binding + + + + + Binding to an ion, a charged atoms or groups of atoms. + GOC:jl + + + + + + + + + + + + + + + + + + + Binding to a cation, a charged atom or group of atoms with a net positive charge. + molecular_function + GO:0043169 + cation binding + + + + + Binding to a cation, a charged atom or group of atoms with a net positive charge. + GOC:jl + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. + GO:0043283 + GO:0044259 + biopolymer metabolic process + macromolecule metabolism + organismal macromolecule metabolism + multicellular organismal macromolecule metabolic process + biological_process + GO:0043170 + + macromolecule metabolic process + + + + + The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. + GOC:mah + + + + + biopolymer metabolic process + GOC:mtg_chebi_dec09 + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. + peptide breakdown + peptide catabolism + peptide degradation + biological_process + GO:0043171 + peptide catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. + GOC:jl + + + + + + + + + + + + + + + + + + + Binding to an amine, a weakly basic organic compound that contains an amino or a substituted amino group. + molecular_function + GO:0043176 + + amine binding + + + + + Binding to an amine, a weakly basic organic compound that contains an amino or a substituted amino group. + GOC:jl + + + + + + + + + + + + + + + + + + + + Binding to an organic acid, any acidic compound containing carbon in covalent linkage. + molecular_function + GO:0043177 + organic acid binding + + + + + Binding to an organic acid, any acidic compound containing carbon in covalent linkage. + GOC:jl + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups. + GO:0010237 + response to amino acid stimulus + biological_process + GO:0043200 + response to amino acid + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups. + GOC:ef + GOC:mlg + + + + + response to amino acid stimulus + GOC:dos + + + + + + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things. + biological_process + GO:0043207 + response to external biotic stimulus + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + An electrically insulating fatty layer that surrounds the axons of many neurons. It is an outgrowth of glial cells: Schwann cells supply the myelin for peripheral neurons while oligodendrocytes supply it to those of the central nervous system. + FMA:62983 + NIF_Subcellular:sao593830697 + Wikipedia:Myelin + Schwann cell myelin sheath + astrocyte sheath + oligodendrocyte myelin sheath + cellular_component + GO:0043209 + myelin sheath + + + + + An electrically insulating fatty layer that surrounds the axons of many neurons. It is an outgrowth of glial cells: Schwann cells supply the myelin for peripheral neurons while oligodendrocytes supply it to those of the central nervous system. + GOC:cjm + GOC:jl + NIF_Subcellular:sao593830697 + Wikipedia:Myelin + + + + + astrocyte sheath + NIF_Subcellular:nlx_subcell_20090204 + + + + + oligodendrocyte myelin sheath + NIF_Subcellular:sao1279474730 + + + + + + + + + Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane. + NIF_Subcellular:sao1539965131 + Wikipedia:Organelle + cellular_component + GO:0043226 + + + + + organelle + + + + + Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. + NIF_Subcellular:sao414196390 + membrane-enclosed organelle + cellular_component + GO:0043227 + membrane-bounded organelle + + + + + Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. + GOC:go_curators + + + + + + + + + Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes. + https://github.com/geneontology/go-ontology/issues/21881 + NIF_Subcellular:sao1456184038 + non-membrane-enclosed organelle + biological condensate + cellular_component + GO:0043228 + + non-membrane-bounded organelle + + + + + Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. + cellular_component + GO:0043229 + + intracellular organelle + + + + + Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + + + + + Organized structure of distinctive morphology and function, occurring outside the cell. Includes, for example, extracellular membrane vesicles (EMVs) and the cellulosomes of anaerobic bacteria and fungi. + cellular_component + GO:0043230 + + extracellular organelle + + + + + Organized structure of distinctive morphology and function, occurring outside the cell. Includes, for example, extracellular membrane vesicles (EMVs) and the cellulosomes of anaerobic bacteria and fungi. + GOC:jl + PMID:9914479 + + + + + + + + + + + + + + + + + + + + Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. + intracellular membrane-enclosed organelle + cellular_component + GO:0043231 + + intracellular membrane-bounded organelle + + + + + Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes. + intracellular non-membrane-enclosed organelle + cellular_component + GO:0043232 + + intracellular non-membrane-bounded organelle + + + + + Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any protein complex that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. + cellular_component + GO:0043235 + + receptor complex + + + + + Any protein complex that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for an erythrocyte to attain its fully functional state. + RBC maturation + red blood cell maturation + biological_process + GO:0043249 + erythrocyte maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for an erythrocyte to attain its fully functional state. + GOC:devbiol + GOC:jl + + + + + RBC maturation + CL:0000232 + + + + + red blood cell maturation + CL:0000232 + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of protein complex assembly. + biological_process + regulation of protein complex assembly + GO:0043254 + regulation of protein-containing complex assembly + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate or extent of protein complex assembly. + GOC:jl + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of carbohydrates. + regulation of carbohydrate anabolism + regulation of carbohydrate biosynthesis + regulation of carbohydrate formation + regulation of carbohydrate synthesis + biological_process + GO:0043255 + regulation of carbohydrate biosynthetic process + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of carbohydrates. + GOC:jl + + + + + + + + + + + + + + + + + + + Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring outside the cell. + extracellular non-membrane-enclosed organelle + cellular_component + GO:0043264 + extracellular non-membrane-bounded organelle + + + + + Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring outside the cell. + GOC:jl + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + biological_process + GO:0043269 + regulation of ion transport + + + + + Any process that modulates the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:jl + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + up regulation of ion transport + up-regulation of ion transport + upregulation of ion transport + activation of ion transport + stimulation of ion transport + biological_process + GO:0043270 + positive regulation of ion transport + + + + + Any process that activates or increases the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:jl + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + down regulation of ion transport + down-regulation of ion transport + downregulation of ion transport + inhibition of ion transport + biological_process + GO:0043271 + negative regulation of ion transport + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:jl + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the pharyngeal muscle over time, from its formation to the mature structure. A pharyngeal muscle is any muscle that forms part of the pharynx. + biological_process + GO:0043282 + pharyngeal muscle development + + + + + The process whose specific outcome is the progression of the pharyngeal muscle over time, from its formation to the mature structure. A pharyngeal muscle is any muscle that forms part of the pharynx. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + Fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle. + contractile fibre + cellular_component + GO:0043292 + contractile fiber + + + + + Fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle. + GOC:go_curators + ISBN:0815316194 + + + + + + + + + A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in some invertebrates, such as Drosophila, is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability. + apical cell junction complex + apical junction + cellular_component + GO:0043296 + apical junction complex + + + + + A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in some invertebrates, such as Drosophila, is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability. + GOC:go_curators + GOC:kmv + PMID:12525486 + PMID:15196556 + + + + + apical cell junction complex + GOC:mah + + + + + + + + + + + + + + + + + + + The formation of an apical junction, a functional unit located near the cell apex at the points of contact between epithelial cells composed of the tight junction, the zonula adherens junction and the desmosomes, by the aggregation, arrangement and bonding together of its constituents. + apical junction complex assembly + biological_process + GO:0043297 + apical junction assembly + + + + + The formation of an apical junction, a functional unit located near the cell apex at the points of contact between epithelial cells composed of the tight junction, the zonula adherens junction and the desmosomes, by the aggregation, arrangement and bonding together of its constituents. + GOC:go_curators + PMID:10854689 + PMID:14729475 + PMID:15196556 + + + + + apical junction complex assembly + GOC:mah + + + + + + + + + + + + + + + + + + + + + The regulated exocytosis of secretory granules by a leukocyte. + immune cell degranulation + immune cell granule exocytosis + leucocyte degranulation + leukocyte granule exocytosis + biological_process + GO:0043299 + leukocyte degranulation + + + + + The regulated exocytosis of secretory granules by a leukocyte. + GOC:add + GO_REF:0000022 + ISBN:0781735149 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate, or extent of leukocyte degranulation. + regulation of immune cell degranulation + regulation of immune cell granule exocytosis + regulation of leucocyte degranulation + regulation of leukocyte granule exocytosis + biological_process + GO:0043300 + regulation of leukocyte degranulation + + + + + Any process that modulates the frequency, rate, or extent of leukocyte degranulation. + GOC:add + ISBN:0781735149 + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the rate of leukocyte degranulation. + down regulation of leukocyte degranulation + down-regulation of leukocyte degranulation + downregulation of leukocyte degranulation + negative regulation of immune cell degranulation + negative regulation of leucocyte degranulation + inhibition of leukocyte degranulation + biological_process + GO:0043301 + negative regulation of leukocyte degranulation + + + + + Any process that stops, prevents, or reduces the rate of leukocyte degranulation. + GOC:add + ISBN:0781735149 + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of leukocyte degranulation. + positive regulation of immune cell degranulation + positive regulation of leucocyte degranulation + up regulation of leukocyte degranulation + up-regulation of leukocyte degranulation + upregulation of leukocyte degranulation + activation of leukocyte degranulation + stimulation of leukocyte degranulation + biological_process + GO:0043302 + positive regulation of leukocyte degranulation + + + + + Any process that activates or increases the frequency, rate or extent of leukocyte degranulation. + GOC:add + ISBN:0781735149 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of protein binding. + biological_process + GO:0043393 + regulation of protein binding + + + + + Any process that modulates the frequency, rate or extent of protein binding. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Binding to a proteoglycan, any glycoprotein in which the carbohydrate units are glycosaminoglycans. + molecular_function + GO:0043394 + proteoglycan binding + + + + + Binding to a proteoglycan, any glycoprotein in which the carbohydrate units are glycosaminoglycans. + ISBN:0198506732 + + + + + + + + + + + + + + + The series of molecular signals mediated by a steroid hormone binding to a receptor. + steroid hormone mediated signalling + biological_process + GO:0043401 + steroid hormone mediated signaling pathway + + + + + The series of molecular signals mediated by a steroid hormone binding to a receptor. + PMID:12606724 + + + + + + + + + + + + + + + The series of molecular signals mediated by the detection of a glucocorticoid hormone. + glucocorticoid mediated signalling + biological_process + GO:0043402 + glucocorticoid mediated signaling pathway + + + + + The series of molecular signals mediated by the detection of a glucocorticoid hormone. + PMID:15240347 + + + + + + + + + + + + + + + + + + + + The regrowth of skeletal muscle tissue to repair injured or damaged muscle fibers in the postnatal stage. + biological_process + myofiber turnover + GO:0043403 + skeletal muscle tissue regeneration + + + + + The regrowth of skeletal muscle tissue to repair injured or damaged muscle fibers in the postnatal stage. + GOC:ef + GOC:mtg_muscle + PMID:12021255 + PMID:16607119 + + + + + + + + + The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties. + biological_process + GO:0043412 + + macromolecule modification + + + + + The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that activates or increase the rate of skeletal muscle regeneration. + up regulation of skeletal muscle regeneration + up-regulation of skeletal muscle regeneration + upregulation of skeletal muscle regeneration + activation of skeletal muscle regeneration + stimulation of skeletal muscle regeneration + biological_process + GO:0043415 + positive regulation of skeletal muscle tissue regeneration + + + + + Any process that activates or increase the rate of skeletal muscle regeneration. + GOC:jl + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of skeletal muscle. + biological_process + GO:0043416 + regulation of skeletal muscle tissue regeneration + + + + + Any process that modulates the frequency, rate or extent of skeletal muscle. + GOC:jl + + + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle regeneration. + down regulation of skeletal muscle regeneration + down-regulation of skeletal muscle regeneration + downregulation of skeletal muscle regeneration + inhibition of skeletal muscle regeneration + biological_process + GO:0043417 + negative regulation of skeletal muscle tissue regeneration + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle regeneration. + GOC:jl + + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals. + response to peptide hormone stimulus + response to polypeptide hormone stimulus + biological_process + GO:0043434 + response to peptide hormone + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals. + PMID:11027914 + PMID:15134857 + Wikipedia:Peptide_hormone + + + + + response to peptide hormone stimulus + GOC:dos + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons). + keto acid metabolic process + keto acid metabolism + ketoacid metabolic process + ketoacid metabolism + oxo acid metabolic process + oxo acid metabolism + oxoacid metabolism + biological_process + GO:0043436 + oxoacid metabolic process + + + + + The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons). + Wikipedia:Oxyacid + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of secondary metabolism, the chemical reactions and pathways involving compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. + regulation of secondary metabolism + biological_process + GO:0043455 + regulation of secondary metabolic process + + + + + Any process that modulates the frequency, rate or extent of secondary metabolism, the chemical reactions and pathways involving compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. + GOC:jl + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and the processes involved in the liberation of energy from these substances. + biological_process + GO:0043467 + regulation of generation of precursor metabolites and energy + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and the processes involved in the liberation of energy from these substances. + GOC:jl + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of carbohydrates. + biological_process + GO:0043470 + regulation of carbohydrate catabolic process + + + + + Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of carbohydrates. + GOC:mlg + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of carbohydrates, carried out by individual cells. + biological_process + GO:0043471 + regulation of cellular carbohydrate catabolic process + + + + + Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of carbohydrates, carried out by individual cells. + GOC:jl + + + + + + + + + + + + + + + + + + + + + The accumulation of pigment in an organism, tissue or cell, either by increased deposition or by increased number of cells. + biological_process + GO:0043473 + + + pigmentation + + + + + The accumulation of pigment in an organism, tissue or cell, either by increased deposition or by increased number of cells. + GOC:jl + + + + + + + + + + + + + + + + A process in which muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities. + biological_process + muscle plasticity + GO:0043500 + + muscle adaptation + + + + + A process in which muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities. + GOC:mtg_muscle + PMID:11181628 + PMID:11449884 + PMID:12605307 + + + + + + + + + + + + + + + + + + + + Any process in which skeletal muscles change their phenotypic profiles in response to altered functional demands and a variety of signals. + biological_process + skeletal muscle plasticity + GO:0043501 + skeletal muscle adaptation + + + + + Any process in which skeletal muscles change their phenotypic profiles in response to altered functional demands and a variety of signals. + GOC:mtg_muscle + PMID:11181628 + PMID:11449884 + PMID:12605307 + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of muscle adaptation. + biological_process + regulation of muscle plasticity + GO:0043502 + regulation of muscle adaptation + + + + + Any process that modulates the frequency, rate or extent of muscle adaptation. + GOC:go_curators + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + + The orderly movement of an endothelial cell into the extracellular matrix in order to form new blood vessels during angiogenesis. + biological_process + GO:0043534 + blood vessel endothelial cell migration + + + + + The orderly movement of an endothelial cell into the extracellular matrix in order to form new blood vessels during angiogenesis. + PMID:11166264 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the migration of the endothelial cells of blood vessels. + biological_process + GO:0043535 + regulation of blood vessel endothelial cell migration + + + + + Any process that modulates the frequency, rate or extent of the migration of the endothelial cells of blood vessels. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels. + up regulation of blood vessel endothelial cell migration + up-regulation of blood vessel endothelial cell migration + upregulation of blood vessel endothelial cell migration + activation of blood vessel endothelial cell migration + stimulation of blood vessel endothelial cell migration + biological_process + GO:0043536 + positive regulation of blood vessel endothelial cell migration + + + + + Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the migration of the endothelial cells of blood vessels. + down regulation of blood vessel endothelial cell migration + down-regulation of blood vessel endothelial cell migration + downregulation of blood vessel endothelial cell migration + inhibition of blood vessel endothelial cell migration + biological_process + GO:0043537 + negative regulation of blood vessel endothelial cell migration + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the migration of the endothelial cells of blood vessels. + GOC:go_curators + + + + + + + + + + + + + + + + + + + The orderly movement of an endothelial cell into the extracellular matrix to form an endothelium. + biological_process + GO:0043542 + endothelial cell migration + + + + + The orderly movement of an endothelial cell into the extracellular matrix to form an endothelium. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. + biological_process + GO:0043549 + regulation of kinase activity + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule. + GOC:bf + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Binding to insulin, a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms. + + molecular_function + GO:0043559 + insulin binding + + + + + Binding to insulin, a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms. + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the process of gaseous exchange between an organism and its environment. + biological_process + GO:0043576 + regulation of respiratory gaseous exchange + + + + + Any process that modulates the frequency, rate or extent of the process of gaseous exchange between an organism and its environment. + GOC:jl + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the ear over time, from its formation to the mature structure. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals. + hearing organ development + biological_process + GO:0043583 + ear development + + + + + The process whose specific outcome is the progression of the ear over time, from its formation to the mature structure. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals. + GOC:jl + ISBN:0192801023 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the nose over time, from its formation to the mature structure. The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity). + nasus development + biological_process + GO:0043584 + nose development + + + + + The process whose specific outcome is the progression of the nose over time, from its formation to the mature structure. The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity). + GOC:jl + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the nose are generated and organized. The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity). + nasus morphogenesis + biological_process + GO:0043585 + nose morphogenesis + + + + + The process in which the anatomical structures of the nose are generated and organized. The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity). + GOC:jl + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the tongue over time, from its formation to the mature structure. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in many other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech. + glossa development + lingua development + biological_process + GO:0043586 + tongue development + + + + + The process whose specific outcome is the progression of the tongue over time, from its formation to the mature structure. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in many other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech. + GOC:jl + UBERON:0001723 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the tongue are generated and organized. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in man other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech. + lingua morphogenesis + glossa morphogenesis + biological_process + GO:0043587 + tongue morphogenesis + + + + + The process in which the anatomical structures of the tongue are generated and organized. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in man other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech. + GOC:jl + UBERON:0001723 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue. + + + animal skin development + biological_process + GO:0043588 + skin development + + + + + The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue. + GOC:jl + UBERON:0002097 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the skin are generated and organized. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner, sensitive and vascular dermis (cutis, corium or true skin) composed mostly of connective tissue. + biological_process + GO:0043589 + skin morphogenesis + + + + + The process in which the anatomical structures of the skin are generated and organized. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner, sensitive and vascular dermis (cutis, corium or true skin) composed mostly of connective tissue. + GOC:jl + UBERON:0002097 + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways involving an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group, as carried out by individual cells. + amide metabolism + biological_process + GO:0043603 + + cellular amide metabolic process + + + + + The chemical reactions and pathways involving an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group, as carried out by individual cells. + GOC:curators + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group. + biological_process + GO:0043604 + amide biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group. + GOC:curators + + + + + + + + + + + + + + + + + + + + The orderly movement of an astrocyte, a class of large neuroglial (macroglial) cells in the central nervous system, the largest and most numerous neuroglial cells in the brain and spinal cord. + astrocyte migration + astrocytic glial cell migration + biological_process + GO:0043615 + astrocyte cell migration + + + + + The orderly movement of an astrocyte, a class of large neuroglial (macroglial) cells in the central nervous system, the largest and most numerous neuroglial cells in the brain and spinal cord. + CL:0000127 + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population. Keratinocytes are epidermal cells which synthesize keratin and undergo a characteristic change as they move upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. + + biological_process + GO:0043616 + keratinocyte proliferation + + + + + The multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population. Keratinocytes are epidermal cells which synthesize keratin and undergo a characteristic change as they move upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. + CL:0000311 + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing two carboxyl (COOH) groups or anions (COO-). + dicarboxylate metabolic process + dicarboxylate metabolism + dicarboxylic acid metabolism + biological_process + GO:0043648 + dicarboxylic acid metabolic process + + + + + The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing two carboxyl (COOH) groups or anions (COO-). + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups. + dicarboxylate catabolic process + dicarboxylate catabolism + dicarboxylic acid breakdown + dicarboxylic acid catabolism + dicarboxylic acid degradation + biological_process + GO:0043649 + dicarboxylic acid catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups. + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups. + dicarboxylate biosynthesis + dicarboxylate biosynthetic process + dicarboxylic acid anabolism + dicarboxylic acid biosynthesis + dicarboxylic acid formation + dicarboxylic acid synthesis + biological_process + GO:0043650 + dicarboxylic acid biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups. + ISBN:0198506732 + + + + + + + + + + The series of events in which a pheromone stimulus is received by a cell and converted into a molecular signal. + biological_process + GO:0043695 + detection of pheromone + + + + + The series of events in which a pheromone stimulus is received by a cell and converted into a molecular signal. + GOC:mah + + + + + + + + + + + + + + + + + + + The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in the progression of the skeleton from its formation to its mature state. + ossification involved in skeletal development + ossification involved in bone modeling + biological_process + GO:0043931 + ossification involved in bone maturation + + + + + The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in the progression of the skeleton from its formation to its mature state. + GOC:dph + GOC:mah + GOC:mtg_mpo + + + + + ossification involved in skeletal development + GOC:dph + + + + + ossification involved in bone modeling + GO_REF:0000034 + + + + + + + + + + + + + + + + + + + Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex. + https://github.com/geneontology/go-ontology/issues/22580 + mah + 2010-09-08T10:01:42Z + GO:0034600 + GO:0034621 + GO:0071822 + protein complex subunit organisation + protein complex subunit organization + biological_process + cellular macromolecular complex organization + cellular macromolecular complex subunit organisation + cellular macromolecular complex subunit organization + macromolecular complex organization + macromolecular complex subunit organisation + macromolecular complex subunit organization + protein-containing complex subunit organization + GO:0043933 + protein-containing complex organization + + + + + Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex. + GOC:mah + + + + + protein complex subunit organisation + GOC:mah + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues. + glucan metabolism + biological_process + GO:0044042 + glucan metabolic process + + + + + The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues. + GOC:jl + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system. + biological_process + GO:0044057 + regulation of system process + + + + + Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system. + GOC:jl + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. + biological_process + GO:0044058 + regulation of digestive system process + + + + + Any process that modulates the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. + GOC:jl + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of an endocrine process, a process involving the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system. + regulation of endocrine system process + biological_process + GO:0044060 + regulation of endocrine process + + + + + Any process that modulates the frequency, rate or extent of an endocrine process, a process involving the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system. + GOC:jl + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate, or extent of excretion, the elimination by an organism of the waste products that arise as a result of metabolic activity. + biological_process + GO:0044062 + regulation of excretion + + + + + Any process that modulates the frequency, rate, or extent of excretion, the elimination by an organism of the waste products that arise as a result of metabolic activity. + GOC:jl + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of a respiratory system process, an organ system process carried out by any of the organs or tissues of the respiratory system. + biological_process + GO:0044065 + regulation of respiratory system process + + + + + Any process that modulates the frequency, rate or extent of a respiratory system process, an organ system process carried out by any of the organs or tissues of the respiratory system. + GOC:jl + + + + + + + + + A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component. + GO:0071843 + cellular component biogenesis at cellular level + biological_process + GO:0044085 + + cellular component biogenesis + + + + + A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component. + GOC:jl + GOC:mah + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. + biological_process + GO:0044087 + regulation of cellular component biogenesis + + + + + Any process that modulates the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. + GOC:jl + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole. + regulation of vacuole organisation + biological_process + regulation of vacuole biogenesis + GO:0044088 + regulation of vacuole organization + + + + + Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole. + GOC:jl + GOC:mah + + + + + regulation of vacuole organisation + GOC:mah + + + + + regulation of vacuole biogenesis + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. + biological_process + GO:0044089 + positive regulation of cellular component biogenesis + + + + + Any process that activates or increases the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. + GOC:jl + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole. + positive regulation of vacuole organisation + biological_process + positive regulation of vacuole biogenesis + GO:0044090 + positive regulation of vacuole organization + + + + + Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole. + GOC:jl + GOC:mah + + + + + positive regulation of vacuole organisation + GOC:mah + + + + + positive regulation of vacuole biogenesis + GOC:mah + + + + + + + + + + + + + + + + + + + A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a membrane. + biological_process + GO:0044091 + membrane biogenesis + + + + + A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a membrane. + GOC:jl + + + + + + + + + + + + + + + + + + + + Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. + jl + 2009-04-21T04:07:27Z + biological_process + GO:0044092 + negative regulation of molecular function + + + + + Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. + GO:jl + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. + jl + 2009-04-21T04:11:06Z + biological_process + GO:0044093 + positive regulation of molecular function + + + + + Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. + GO:jl + + + + + + + + + + The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group, as carried out by individual cells. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom. + jl + 2009-07-15T11:55:44Z + biological_process + GO:0044106 + cellular amine metabolic process + + + + + The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group, as carried out by individual cells. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom. + GOC:jl + + + + + + + + + + The chemical reactions and pathways by which individual cells transform chemical substances. + cellular metabolism + biological_process + intermediary metabolism + GO:0044237 + + cellular metabolic process + + + + + The chemical reactions and pathways by which individual cells transform chemical substances. + GOC:go_curators + + + + + intermediary metabolism + GOC:mah + + + + + + + + + The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. + primary metabolism + biological_process + GO:0044238 + + primary metabolic process + + + + + The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. + GOC:go_curators + http://www.metacyc.org + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of polysaccharides, polymers of many (typically more than 10) monosaccharide residues linked glycosidically, as carried out by individual cells. + cellular polysaccharide breakdown + cellular polysaccharide catabolism + cellular polysaccharide degradation + biological_process + GO:0044247 + cellular polysaccharide catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of polysaccharides, polymers of many (typically more than 10) monosaccharide residues linked glycosidically, as carried out by individual cells. + GOC:jl + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells. + cellular breakdown + cellular catabolism + cellular degradation + biological_process + GO:0044248 + cellular catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells. + GOC:jl + + + + + + + + + + The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. + cellular anabolism + cellular biosynthesis + cellular formation + cellular synthesis + biological_process + GO:0044249 + cellular biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells. + GOC:jl + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown into fatty acids and monoglycerides of lipids in the small intestine. Lipids are broken down by lipases released by the pancreas. + intestinal lipid breakdown + intestinal lipid catabolism + intestinal lipid degradation + biological_process + GO:0044258 + intestinal lipid catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown into fatty acids and monoglycerides of lipids in the small intestine. Lipids are broken down by lipases released by the pancreas. + GOC:jl + http://www.emc.maricopa.edu/ + + + + + + + + + + The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells. + GO:0034960 + cellular biopolymer metabolic process + cellular macromolecule metabolism + biological_process + GO:0044260 + cellular macromolecule metabolic process + + + + + The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells. + GOC:mah + + + + + cellular biopolymer metabolic process + GOC:mtg_chebi_dec09 + + + + + + + + + + The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells. + GO:0006092 + cellular carbohydrate metabolism + main pathways of carbohydrate metabolic process + main pathways of carbohydrate metabolism + biological_process + GO:0044262 + cellular carbohydrate metabolic process + + + + + The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells. + GOC:jl + + + + + + + + + + + The chemical reactions and pathways involving polysaccharides, polymers of more than 10 monosaccharide residues joined by glycosidic linkages, as carried out by individual cells. + cellular glycan metabolic process + cellular glycan metabolism + cellular polysaccharide metabolism + biological_process + GO:0044264 + cellular polysaccharide metabolic process + + + + + The chemical reactions and pathways involving polysaccharides, polymers of more than 10 monosaccharide residues joined by glycosidic linkages, as carried out by individual cells. + GOC:jl + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of a macromolecule, any large molecule including proteins, nucleic acids and carbohydrates, as carried out by individual cells. + GO:0034962 + cellular biopolymer catabolic process + cellular macromolecule breakdown + cellular macromolecule catabolism + cellular macromolecule degradation + biological_process + GO:0044265 + cellular macromolecule catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of a macromolecule, any large molecule including proteins, nucleic acids and carbohydrates, as carried out by individual cells. + GOC:jl + + + + + cellular biopolymer catabolic process + GOC:mtg_chebi_dec09 + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of organic and inorganic nitrogenous compounds. + nitrogen compound breakdown + nitrogen compound catabolism + nitrogen compound degradation + biological_process + GO:0044270 + cellular nitrogen compound catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of organic and inorganic nitrogenous compounds. + GOC:jl + ISBN:0198506732 + + + + + + + + + + The chemical reactions and pathways resulting in the formation of organic and inorganic nitrogenous compounds. + nitrogen compound anabolism + nitrogen compound biosynthesis + nitrogen compound formation + nitrogen compound synthesis + biological_process + GO:0044271 + cellular nitrogen compound biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of organic and inorganic nitrogenous compounds. + GOC:jl + ISBN:0198506732 + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells. + cellular carbohydrate breakdown + cellular carbohydrate catabolism + cellular carbohydrate degradation + biological_process + GO:0044275 + cellular carbohydrate catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells. + GOC:jl + + + + + + + + + The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule. + jl + 2010-01-26T12:05:20Z + small molecule metabolism + biological_process + GO:0044281 + + + + Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides. + small molecule metabolic process + + + + + The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule. + GOC:curators + GOC:pde + GOC:vw + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of small molecules, any low molecular weight, monomeric, non-encoded molecule. + jl + 2010-01-26T12:06:10Z + small molecule catabolism + biological_process + GO:0044282 + Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides. + small molecule catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of small molecules, any low molecular weight, monomeric, non-encoded molecule. + GOC:curators + GOC:vw + + + + + + + + + + The chemical reactions and pathways resulting in the formation of small molecules, any low molecular weight, monomeric, non-encoded molecule. + jl + 2010-01-26T12:06:49Z + small molecule biosynthesis + biological_process + GO:0044283 + + Small molecules in GO include monosaccharides but exclude disaccharides and polysaccharides. + small molecule biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of small molecules, any low molecular weight, monomeric, non-encoded molecule. + GOC:curators + GOC:pde + GOC:vw + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections. + + jl + 2010-02-05T10:37:16Z + FBbt:00005107 + FMA:67301 + Wikipedia:Cell_body + cell soma + cellular_component + GO:0044297 + Note that 'cell body' and 'cell soma' are not used in the literature for cells that lack projections, nor for some cells (e.g. yeast with mating projections) that do have projections. + cell body + + + + + The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections. + GOC:go_curators + + + + + + + + + + + + + + + Distinctive, unmyelinated axons produced by granule cells. + jl + 2010-02-05T11:23:55Z + NIF_Subcellular:nlx_subcell_20090601 + dentate gyrus mossy fibre + granule cell axon + cellular_component + GO:0044302 + dentate gyrus mossy fiber + + + + + Distinctive, unmyelinated axons produced by granule cells. + NIF_Subcellular:nlx_subcell_20090601 + PMID:17765709 + + + + + + + + + + + + + + + + + + + A process in which a protein is transported to, or maintained in, a location within the cytoskeleton. + jl + 2011-12-13T11:43:24Z + protein localisation to cytoskeleton + biological_process + GO:0044380 + protein localization to cytoskeleton + + + + + A process in which a protein is transported to, or maintained in, a location within the cytoskeleton. + GOC:jl + + + + + protein localisation to cytoskeleton + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Any process evolved to enable an interaction with an organism of a different species. + https://github.com/geneontology/go-ontology/issues/20191 + + interaction with another species + interspecies interaction + interspecies interaction between organisms + interspecies interaction with other organisms + biological_process + GO:0044419 + + + + biological process involved in interspecies interaction between organisms + + + + + Any process evolved to enable an interaction with an organism of a different species. + GOC:cc + + + + + + + + + + + + + + + + + + + The aggregation, arrangement and bonding together of a set of components to form a motile cilium. + krc + 2015-02-06T17:23:23Z + GO:1903887 + biological_process + motile primary cilia assembly + motile primary cilia formation + motile primary cilium assembly + motile primary cilium formation + nodal cilium assembly + nodal cilium formation + GO:0044458 + motile cilium assembly + + + + + The aggregation, arrangement and bonding together of a set of components to form a motile cilium. + GOC:TermGenie + GOC:cilia + GOC:krc + GO_REF:0000079 + PMID:19776033 + PMID:21129373 + ZFIN:dsf + + + + + motile primary cilia assembly + GOC:TermGenie + + + + + motile primary cilia formation + GOC:TermGenie + + + + + motile primary cilium formation + GOC:TermGenie + + + + + nodal cilium assembly + GOC:TermGenie + + + + + nodal cilium formation + GOC:TermGenie + + + + + + + + + + The chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. + jl + 2012-03-29T01:55:18Z + secondary metabolite biosynthesis + biological_process + GO:0044550 + + secondary metabolite biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. + GOC:jl + + + + + + + + + + + + + + + + + + + The expansion of a dendritic cell population by cell division. A dendritic cell is a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. + jl + 2012-04-05T04:31:39Z + biological_process + GO:0044565 + dendritic cell proliferation + + + + + The expansion of a dendritic cell population by cell division. A dendritic cell is a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. + CL:0000451 + PMID:18469816 + + + + + + + + + + + + + + + + + + + + A change in the morphology or behavior of a chondrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. A chondrocyte is a polymorphic cell that forms cartilage. + jl + 2012-04-05T04:45:38Z + biological_process + GO:0044566 + chondrocyte activation + + + + + A change in the morphology or behavior of a chondrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. A chondrocyte is a polymorphic cell that forms cartilage. + CL:0000138 + GOC:jl + + + + + + + + + A biological process that directly contributes to the process of producing new individuals, involving another organism. + jl + 2012-09-19T15:56:30Z + biological_process + GO:0044703 + + multi-organism reproductive process + + + + + A biological process that directly contributes to the process of producing new individuals, involving another organism. + GOC:jl + + + + + + + + + A multicellular organism process which involves another multicellular organism of the same or different species. + https://github.com/geneontology/go-ontology/issues/21459 + jl + 2012-09-19T16:06:16Z + biological_process + GO:0044706 + multi-multicellular organism process + + + + + A multicellular organism process which involves another multicellular organism of the same or different species. + GOC:jl + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole. + jl + 2013-03-27T15:09:58Z + microtubule-based flagellum organization + biological_process + GO:0044782 + + + Note that we deem cilium and microtubule-based flagellum to be equivalent. + cilium organization + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole. + GOC:cilia + GOC:jl + + + + + + + + + + + + + + A distinct period or stage in a biological process or cycle. + jl + 2014-07-16T13:12:40Z + biological_process + GO:0044848 + + Note that phases are is_a disjoint from other biological processes. happens_during relationships can operate between phases and other biological processes e.g. DNA replication happens_during S phase. + biological phase + + + + + A distinct period or stage in a biological process or cycle. + GOC:jl + + + + + + + + + + + + + + + + + + + + Any process in which a lipoprotein is transported to, or maintained in, a specific location. + jl + 2014-11-25T16:27:06Z + biological_process + GO:0044872 + lipoprotein localization + + + + + Any process in which a lipoprotein is transported to, or maintained in, a specific location. + GOC:jl + + + + + + + + + + + + + + + + + + + + A process in which a lipoprotein is transported to, or maintained in, a specific location in a membrane. + jl + 2014-11-25T16:28:43Z + biological_process + GO:0044873 + lipoprotein localization to membrane + + + + + A process in which a lipoprotein is transported to, or maintained in, a specific location in a membrane. + GOC:jl + + + + + + + + + + + + + + + + + + + + A process in which a lipoprotein is transported to, or maintained in, a specific location in an outer membrane. + jl + 2014-11-25T16:30:30Z + biological_process + GO:0044874 + lipoprotein localization to outer membrane + + + + + A process in which a lipoprotein is transported to, or maintained in, a specific location in an outer membrane. + GOC:jl + + + + + + + + + + + + + + + + + + + Binding to a macromolecular complex. + jl + 2014-12-16T11:38:58Z + GO:0032403 + protein complex binding + molecular_function + macromolecular complex binding + GO:0044877 + + protein-containing complex binding + + + + + Binding to a macromolecular complex. + GOC:jl + + + + + + + + + + + + + + + + + + + + The joining of the lipid bilayer membrane that surround a cell with that of another cell, producing a single cell. + GO:0006947 + cell fusion + cell-cell fusion + biological_process + GO:0045026 + plasma membrane fusion + + + + + The joining of the lipid bilayer membrane that surround a cell with that of another cell, producing a single cell. + GOC:elh + GOC:mtg_muscle + + + + + + + + + A process of exocytosis in which soluble proteins and other substances are initially stored in secretory vesicles for later release. It is found mainly in cells that are specialized for secreting products such as hormones, neurotransmitters, or digestive enzymes rapidly on demand. + regulated secretory pathway + biological_process + GO:0045055 + regulated exocytosis + + + + + A process of exocytosis in which soluble proteins and other substances are initially stored in secretory vesicles for later release. It is found mainly in cells that are specialized for secreting products such as hormones, neurotransmitters, or digestive enzymes rapidly on demand. + GOC:mah + ISBN:0716731363 + + + + + + + + + + + + + + + + + + + + + The process in which T cells that express T cell receptors that are restricted by self MHC protein complexes and tolerant to self antigens are selected for further maturation. + Wikipedia:Thymocyte + T lymphocyte selection + T-cell selection + T-lymphocyte selection + biological_process + GO:0045058 + T cell selection + + + + + The process in which T cells that express T cell receptors that are restricted by self MHC protein complexes and tolerant to self antigens are selected for further maturation. + ISBN:0781735149 + PMID:12414722 + + + + + + + + + A filament composed of acidic and basic keratins (types I and II), typically expressed in epithelial cells. The keratins are the most diverse classes of IF proteins, with a large number of keratin isoforms being expressed. Each type of epithelium always expresses a characteristic combination of type I and type II keratins. + cellular_component + acidic keratin + basic/neutral keratin + GO:0045095 + keratin filament + + + + + A filament composed of acidic and basic keratins (types I and II), typically expressed in epithelial cells. The keratins are the most diverse classes of IF proteins, with a large number of keratin isoforms being expressed. Each type of epithelium always expresses a characteristic combination of type I and type II keratins. + ISBN:0716731363 + + + + + + + + + Any cellular process that depends upon or alters the intermediate filament cytoskeleton, that part of the cytoskeleton comprising intermediate filaments and their associated proteins. + biological_process + GO:0045103 + intermediate filament-based process + + + + + Any cellular process that depends upon or alters the intermediate filament cytoskeleton, that part of the cytoskeleton comprising intermediate filaments and their associated proteins. + GOC:ai + + + + + + + + + + + + + + + + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising intermediate filaments and their associated proteins. + intermediate filament cytoskeleton organisation + biological_process + intermediate filament cytoskeleton organization and biogenesis + GO:0045104 + intermediate filament cytoskeleton organization + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising intermediate filaments and their associated proteins. + GOC:ai + + + + + intermediate filament cytoskeleton organization and biogenesis + GOC:mah + + + + + + + + + + + + + + + + + + + + Control of the spatial distribution of intermediate filaments; includes organizing filaments into meshworks, bundles, or other structures, as by cross-linking. + intermediate filament organisation + biological_process + GO:0045109 + intermediate filament organization + + + + + Control of the spatial distribution of intermediate filaments; includes organizing filaments into meshworks, bundles, or other structures, as by cross-linking. + GOC:ai + + + + + + + + + + + + + + + + + + + The formation of the bundles of intermediate filaments. Intermediate filament-associated proteins (IFAPs) cross-link intermediate filaments with one another, forming a bundle or a network, and with other cell structures, including the plasma membrane. The organization of intermediate filaments and their supportive function in various cells types depends in large part on their linkage to other cell structures via IFAPs. + tonofilament assembly + biological_process + GO:0045110 + intermediate filament bundle assembly + + + + + The formation of the bundles of intermediate filaments. Intermediate filament-associated proteins (IFAPs) cross-link intermediate filaments with one another, forming a bundle or a network, and with other cell structures, including the plasma membrane. The organization of intermediate filaments and their supportive function in various cells types depends in large part on their linkage to other cell structures via IFAPs. + ISBN:0716731363 + + + + + + + + + Cytoskeletal structure made from intermediate filaments, typically organized in the cytosol as an extended system that stretches from the nuclear envelope to the plasma membrane. Some intermediate filaments run parallel to the cell surface, while others traverse the cytosol; together they form an internal framework that helps support the shape and resilience of the cell. + cellular_component + GO:0045111 + intermediate filament cytoskeleton + + + + + Cytoskeletal structure made from intermediate filaments, typically organized in the cytosol as an extended system that stretches from the nuclear envelope to the plasma membrane. Some intermediate filaments run parallel to the cell surface, while others traverse the cytosol; together they form an internal framework that helps support the shape and resilience of the cell. + ISBN:0716731363 + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the primary sexual characteristics over time, from their formation to the mature structures. The primary sexual characteristics are the testes in males and the ovaries in females and they develop in response to sex hormone secretion. + biological_process + GO:0045137 + development of primary sexual characteristics + + + + + The process whose specific outcome is the progression of the primary sexual characteristics over time, from their formation to the mature structures. The primary sexual characteristics are the testes in males and the ovaries in females and they develop in response to sex hormone secretion. + GOC:ai + + + + + + + + + + + + + + + The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. + biological_process + GO:0045165 + Note that this term was 'cell fate determination' but the term name was changed to better match its existing definition and the child term 'cell fate determination; GO:0001709' was also created. + cell fate commitment + + + + + The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field. + ISBN:0716731185 + + + + + + + + + + + + + + + + + + + Signaling at long or short range between cells that results in the commitment of a cell to a certain fate. + cell fate commitment, cell-cell signaling + cell fate commitment, cell-cell signalling + cell-cell signaling during in cell fate commitment + cell-cell signaling resulting in cell fate commitment + cell-cell signalling during cell fate commitment + cell-cell signalling resulting in cell fate commitment + cell-cell signalling involved in cell fate specification + biological_process + GO:0045168 + cell-cell signaling involved in cell fate commitment + + + + + Signaling at long or short range between cells that results in the commitment of a cell to a certain fate. + GOC:dph + GOC:go_curators + GOC:tb + + + + + cell-cell signalling involved in cell fate specification + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + The directed movement of a protein to a specific location. + establishment of protein localisation + protein positioning + protein recruitment + biological_process + GO:0045184 + establishment of protein localization + + + + + The directed movement of a protein to a specific location. + GOC:bf + + + + + establishment of protein localisation + GOC:mah + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of sleep; a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals. + regulation of sleep + biological_process + GO:0045187 + regulation of circadian sleep/wake cycle, sleep + + + + + Any process that modulates the frequency, rate or extent of sleep; a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals. + GOC:jl + ISBN:0192800981 + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of non-rapid eye movement sleep. + regulation of non-REM sleep + biological_process + GO:0045188 + regulation of circadian sleep/wake cycle, non-REM sleep + + + + + Any process that modulates the frequency, rate or extent of non-rapid eye movement sleep. + GOC:go_curators + + + + + + + + + + + + + + + Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system. + GO:0043339 + GO:0043342 + establishment and/or maintenance of neuroblast cell polarity + biological_process + GO:0045196 + establishment or maintenance of neuroblast polarity + + + + + Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system. + GOC:bf + GOC:mah + GOC:mtg_sensu + PMID:19375318 + PMID:20066083 + + + + + + + + + + + + + + + + + + + + + The specification and formation of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system. + GO:0043340 + GO:0043343 + establishment of neuroblast cell polarity + biological_process + GO:0045200 + establishment of neuroblast polarity + + + + + The specification and formation of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system. + GOC:bf + GOC:mtg_sensu + + + + + + + + + + + + + + + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-cell junction. A cell-cell junction is a specialized region of connection between two cells. + cell-cell junction assembly and maintenance + cell-cell junction organisation + intercellular junction assembly and maintenance + biological_process + cell-cell junction biogenesis + GO:0045216 + cell-cell junction organization + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-cell junction. A cell-cell junction is a specialized region of connection between two cells. + GOC:ai + GOC:dph + GOC:jl + GOC:mah + + + + + cell-cell junction organisation + GOC:mah + + + + + + + + + + + + + + + + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of external structures that lie outside the plasma membrane and surround the entire cell. + external encapsulating structure organisation + external encapsulating structure organization and biogenesis + biological_process + GO:0045229 + + external encapsulating structure organization + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of external structures that lie outside the plasma membrane and surround the entire cell. + GOC:ai + GOC:dph + GOC:jl + GOC:mah + + + + + external encapsulating structure organization and biogenesis + GOC:dph + GOC:jl + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + The precipitation of specific crystal forms of calcium carbonate with extracellular matrix proteins in the otolith organs of the vertebrate inner ear. + biological_process + GO:0045299 + otolith mineralization + + + + + The precipitation of specific crystal forms of calcium carbonate with extracellular matrix proteins in the otolith organs of the vertebrate inner ear. + GOC:dsf + PMID:15581873 + + + + + + + + + + + + + + + + + + + + + A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor. + Wikipedia:Immunologic_activation + immune cell activation + leucocyte activation + biological_process + GO:0045321 + leukocyte activation + + + + + A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor. + GOC:add + + + + + + + + + + + + + + + + + + + + The regulated release of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis. + biological_process + GO:0045443 + juvenile hormone secretion + + + + + The regulated release of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis. + GOC:go_curators + ISBN:0198547684 + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat. + adipocyte cell differentiation + adipocyte differentiation + adipose cell differentiation + biological_process + adipogenesis + GO:0045444 + fat cell differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat. + CL:0000136 + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a mesodermal, bone marrow or neural crest cell acquires specialized features of an endothelial cell, a thin flattened cell. A layer of such cells lines the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium. + biological_process + GO:0045446 + endothelial cell differentiation + + + + + The process in which a mesodermal, bone marrow or neural crest cell acquires specialized features of an endothelial cell, a thin flattened cell. A layer of such cells lines the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium. + CL:0000115 + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the growth of the imaginal disc. + biological_process + GO:0045570 + regulation of imaginal disc growth + + + + + Any process that modulates the frequency, rate or extent of the growth of the imaginal disc. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc growth. + down regulation of imaginal disc growth + down-regulation of imaginal disc growth + downregulation of imaginal disc growth + inhibition of imaginal disc growth + biological_process + GO:0045571 + negative regulation of imaginal disc growth + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc growth. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of imaginal disc growth. + up regulation of imaginal disc growth + up-regulation of imaginal disc growth + upregulation of imaginal disc growth + activation of imaginal disc growth + stimulation of imaginal disc growth + biological_process + GO:0045572 + positive regulation of imaginal disc growth + + + + + Any process that activates or increases the frequency, rate or extent of imaginal disc growth. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of B cell differentiation. + regulation of B lymphocyte differentiation + regulation of B-cell differentiation + regulation of B-lymphocyte differentiation + biological_process + regulation of B cell development + GO:0045577 + Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. + regulation of B cell differentiation + + + + + Any process that modulates the frequency, rate or extent of B cell differentiation. + GOC:go_curators + + + + + regulation of B cell development + GOC:add + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of B cell differentiation. + down regulation of B cell differentiation + down-regulation of B cell differentiation + downregulation of B cell differentiation + negative regulation of B lymphocyte differentiation + negative regulation of B-cell differentiation + negative regulation of B-lymphocyte differentiation + inhibition of B cell differentiation + biological_process + negative regulation of B cell development + GO:0045578 + Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. + negative regulation of B cell differentiation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of B cell differentiation. + GOC:go_curators + + + + + negative regulation of B cell development + GOC:add + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of B cell differentiation. + positive regulation of B lymphocyte differentiation + positive regulation of B-cell differentiation + positive regulation of B-lymphocyte differentiation + up regulation of B cell differentiation + up-regulation of B cell differentiation + upregulation of B cell differentiation + activation of B cell differentiation + stimulation of B cell differentiation + biological_process + positive regulation of B cell development + GO:0045579 + Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. + positive regulation of B cell differentiation + + + + + Any process that activates or increases the frequency, rate or extent of B cell differentiation. + GOC:go_curators + + + + + positive regulation of B cell development + GOC:add + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of T cell differentiation. + regulation of T lymphocyte differentiation + regulation of T-cell differentiation + regulation of T-lymphocyte differentiation + biological_process + regulation of T cell development + GO:0045580 + Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. + regulation of T cell differentiation + + + + + Any process that modulates the frequency, rate or extent of T cell differentiation. + GOC:go_curators + + + + + regulation of T cell development + GOC:add + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation. + down regulation of T cell differentiation + down-regulation of T cell differentiation + downregulation of T cell differentiation + negative regulation of T lymphocyte differentiation + negative regulation of T-cell differentiation + negative regulation of T-lymphocyte differentiation + inhibition of T cell differentiation + biological_process + negative regulation of T cell development + GO:0045581 + Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. + negative regulation of T cell differentiation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation. + GOC:go_curators + + + + + negative regulation of T cell development + GOC:add + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of T cell differentiation. + positive regulation of T lymphocyte differentiation + positive regulation of T-cell differentiation + positive regulation of T-lymphocyte differentiation + up regulation of T cell differentiation + up-regulation of T cell differentiation + upregulation of T cell differentiation + activation of T cell differentiation + stimulation of T cell differentiation + biological_process + positive regulation of T cell development + GO:0045582 + Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. + positive regulation of T cell differentiation + + + + + Any process that activates or increases the frequency, rate or extent of T cell differentiation. + GOC:go_curators + + + + + positive regulation of T cell development + GOC:add + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features. + biological_process + GO:0045595 + regulation of cell differentiation + + + + + Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation. + down regulation of cell differentiation + down-regulation of cell differentiation + downregulation of cell differentiation + inhibition of cell differentiation + biological_process + GO:0045596 + negative regulation of cell differentiation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of cell differentiation. + up regulation of cell differentiation + up-regulation of cell differentiation + upregulation of cell differentiation + activation of cell differentiation + stimulation of cell differentiation + biological_process + GO:0045597 + positive regulation of cell differentiation + + + + + Any process that activates or increases the frequency, rate or extent of cell differentiation. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of adipocyte differentiation. + regulation of adipocyte cell differentiation + regulation of adipocyte differentiation + biological_process + GO:0045598 + regulation of fat cell differentiation + + + + + Any process that modulates the frequency, rate or extent of adipocyte differentiation. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of adipocyte differentiation. + down regulation of fat cell differentiation + down-regulation of fat cell differentiation + downregulation of fat cell differentiation + negative regulation of adipocyte cell differentiation + negative regulation of adipocyte differentiation + inhibition of fat cell differentiation + biological_process + GO:0045599 + negative regulation of fat cell differentiation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of adipocyte differentiation. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of adipocyte differentiation. + positive regulation of adipocyte cell differentiation + positive regulation of adipocyte differentiation + up regulation of fat cell differentiation + up-regulation of fat cell differentiation + upregulation of fat cell differentiation + activation of fat cell differentiation + stimulation of fat cell differentiation + biological_process + GO:0045600 + positive regulation of fat cell differentiation + + + + + Any process that activates or increases the frequency, rate or extent of adipocyte differentiation. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of endothelial cell differentiation. + biological_process + GO:0045601 + regulation of endothelial cell differentiation + + + + + Any process that modulates the frequency, rate or extent of endothelial cell differentiation. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of endothelial cell differentiation. + down regulation of endothelial cell differentiation + down-regulation of endothelial cell differentiation + downregulation of endothelial cell differentiation + inhibition of endothelial cell differentiation + biological_process + GO:0045602 + negative regulation of endothelial cell differentiation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of endothelial cell differentiation. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of endothelial cell differentiation. + up regulation of endothelial cell differentiation + up-regulation of endothelial cell differentiation + upregulation of endothelial cell differentiation + activation of endothelial cell differentiation + stimulation of endothelial cell differentiation + biological_process + GO:0045603 + positive regulation of endothelial cell differentiation + + + + + Any process that activates or increases the frequency, rate or extent of endothelial cell differentiation. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of epidermal cell differentiation. + biological_process + regulation of hypodermal cell differentiation + GO:0045604 + regulation of epidermal cell differentiation + + + + + Any process that modulates the frequency, rate or extent of epidermal cell differentiation. + GOC:go_curators + + + + + regulation of hypodermal cell differentiation + GOC:kmv + GOC:rk + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal cell differentiation. + down regulation of epidermal cell differentiation + down-regulation of epidermal cell differentiation + downregulation of epidermal cell differentiation + inhibition of epidermal cell differentiation + biological_process + negative regulation of hypodermal cell differentiation + GO:0045605 + negative regulation of epidermal cell differentiation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal cell differentiation. + GOC:go_curators + + + + + negative regulation of hypodermal cell differentiation + GOC:kmv + GOC:rk + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of epidermal cell differentiation. + up regulation of epidermal cell differentiation + up-regulation of epidermal cell differentiation + upregulation of epidermal cell differentiation + activation of epidermal cell differentiation + stimulation of epidermal cell differentiation + biological_process + positive regulation of hypodermal cell differentiation + GO:0045606 + positive regulation of epidermal cell differentiation + + + + + Any process that activates or increases the frequency, rate or extent of epidermal cell differentiation. + GOC:go_curators + + + + + positive regulation of hypodermal cell differentiation + GOC:kmv + GOC:rk + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of auditory hair cell differentiation. + regulation of auditory hair cell differentiation + biological_process + regulation of auditory receptor cell differentiation + GO:0045607 + regulation of inner ear auditory receptor cell differentiation + + + + + Any process that modulates the frequency, rate or extent of auditory hair cell differentiation. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of auditory hair cell differentiation. + down regulation of auditory receptor cell differentiation + down-regulation of auditory receptor cell differentiation + downregulation of auditory receptor cell differentiation + negative regulation of auditory hair cell differentiation + inhibition of auditory receptor cell differentiation + biological_process + negative regulation of auditory receptor cell differentiation + GO:0045608 + negative regulation of inner ear auditory receptor cell differentiation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of auditory hair cell differentiation. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of auditory hair cell differentiation. + positive regulation of auditory hair cell differentiation + up regulation of auditory receptor cell differentiation + up-regulation of auditory receptor cell differentiation + upregulation of auditory receptor cell differentiation + activation of auditory receptor cell differentiation + stimulation of auditory receptor cell differentiation + biological_process + positive regulation of auditory receptor cell differentiation + GO:0045609 + positive regulation of inner ear auditory receptor cell differentiation + + + + + Any process that activates or increases the frequency, rate or extent of auditory hair cell differentiation. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of hemocyte differentiation. + regulation of arthropod blood cell differentiation + biological_process + GO:0045610 + regulation of hemocyte differentiation + + + + + Any process that modulates the frequency, rate or extent of hemocyte differentiation. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of hemocyte differentiation. + down regulation of hemocyte differentiation + down-regulation of hemocyte differentiation + downregulation of hemocyte differentiation + negative regulation of arthropod blood cell differentiation + inhibition of hemocyte differentiation + biological_process + GO:0045611 + negative regulation of hemocyte differentiation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of hemocyte differentiation. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of hemocyte differentiation. + positive regulation of arthropod blood cell differentiation + up regulation of hemocyte differentiation + up-regulation of hemocyte differentiation + upregulation of hemocyte differentiation + activation of hemocyte differentiation + stimulation of hemocyte differentiation + biological_process + GO:0045612 + positive regulation of hemocyte differentiation + + + + + Any process that activates or increases the frequency, rate or extent of hemocyte differentiation. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of keratinocyte differentiation. + biological_process + GO:0045616 + regulation of keratinocyte differentiation + + + + + Any process that modulates the frequency, rate or extent of keratinocyte differentiation. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of keratinocyte differentiation. + down regulation of keratinocyte differentiation + down-regulation of keratinocyte differentiation + downregulation of keratinocyte differentiation + inhibition of keratinocyte differentiation + biological_process + GO:0045617 + negative regulation of keratinocyte differentiation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of keratinocyte differentiation. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of keratinocyte differentiation. + up regulation of keratinocyte differentiation + up-regulation of keratinocyte differentiation + upregulation of keratinocyte differentiation + activation of keratinocyte differentiation + stimulation of keratinocyte differentiation + biological_process + GO:0045618 + positive regulation of keratinocyte differentiation + + + + + Any process that activates or increases the frequency, rate or extent of keratinocyte differentiation. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of lymphocyte differentiation. + biological_process + regulation of lymphocyte development + GO:0045619 + Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. + regulation of lymphocyte differentiation + + + + + Any process that modulates the frequency, rate or extent of lymphocyte differentiation. + GOC:go_curators + + + + + regulation of lymphocyte development + GOC:add + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte differentiation. + down regulation of lymphocyte differentiation + down-regulation of lymphocyte differentiation + downregulation of lymphocyte differentiation + inhibition of lymphocyte differentiation + biological_process + negative regulation of lymphocyte development + GO:0045620 + Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. + negative regulation of lymphocyte differentiation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte differentiation. + GOC:go_curators + + + + + negative regulation of lymphocyte development + GOC:add + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of lymphocyte differentiation. + up regulation of lymphocyte differentiation + up-regulation of lymphocyte differentiation + upregulation of lymphocyte differentiation + activation of lymphocyte differentiation + stimulation of lymphocyte differentiation + biological_process + positive regulation of lymphocyte development + GO:0045621 + Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'. + positive regulation of lymphocyte differentiation + + + + + Any process that activates or increases the frequency, rate or extent of lymphocyte differentiation. + GOC:go_curators + + + + + positive regulation of lymphocyte development + GOC:add + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of mechanoreceptor differentiation. + biological_process + GO:0045631 + regulation of mechanoreceptor differentiation + + + + + Any process that modulates the frequency, rate or extent of mechanoreceptor differentiation. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of mechanoreceptor differentiation. + down regulation of mechanoreceptor differentiation + down-regulation of mechanoreceptor differentiation + downregulation of mechanoreceptor differentiation + inhibition of mechanoreceptor differentiation + biological_process + GO:0045632 + negative regulation of mechanoreceptor differentiation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of mechanoreceptor differentiation. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of mechanoreceptor differentiation. + up regulation of mechanoreceptor differentiation + up-regulation of mechanoreceptor differentiation + upregulation of mechanoreceptor differentiation + activation of mechanoreceptor differentiation + stimulation of mechanoreceptor differentiation + biological_process + GO:0045633 + positive regulation of mechanoreceptor differentiation + + + + + Any process that activates or increases the frequency, rate or extent of mechanoreceptor differentiation. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of melanocyte differentiation. + regulation of melanophore differentiation + biological_process + GO:0045634 + regulation of melanocyte differentiation + + + + + Any process that modulates the frequency, rate or extent of melanocyte differentiation. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of melanocyte differentiation. + down regulation of melanocyte differentiation + down-regulation of melanocyte differentiation + downregulation of melanocyte differentiation + negative regulation of melanophore differentiation + inhibition of melanocyte differentiation + biological_process + GO:0045635 + negative regulation of melanocyte differentiation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of melanocyte differentiation. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of melanocyte differentiation. + positive regulation of melanophore differentiation + up regulation of melanocyte differentiation + up-regulation of melanocyte differentiation + upregulation of melanocyte differentiation + activation of melanocyte differentiation + stimulation of melanocyte differentiation + biological_process + GO:0045636 + positive regulation of melanocyte differentiation + + + + + Any process that activates or increases the frequency, rate or extent of melanocyte differentiation. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of myeloid cell differentiation. + biological_process + GO:0045637 + regulation of myeloid cell differentiation + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate or extent of myeloid cell differentiation. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation. + down regulation of myeloid cell differentiation + down-regulation of myeloid cell differentiation + downregulation of myeloid cell differentiation + inhibition of myeloid cell differentiation + biological_process + GO:0045638 + negative regulation of myeloid cell differentiation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of myeloid cell differentiation. + up regulation of myeloid cell differentiation + up-regulation of myeloid cell differentiation + upregulation of myeloid cell differentiation + activation of myeloid cell differentiation + stimulation of myeloid cell differentiation + biological_process + GO:0045639 + positive regulation of myeloid cell differentiation + + + + + Any process that activates or increases the frequency, rate or extent of myeloid cell differentiation. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of erythrocyte differentiation. + regulation of RBC differentiation + regulation of red blood cell differentiation + biological_process + GO:0045646 + regulation of erythrocyte differentiation + + + + + Any process that modulates the frequency, rate or extent of erythrocyte differentiation. + GOC:go_curators + + + + + regulation of RBC differentiation + CL:0000232 + + + + + regulation of red blood cell differentiation + CL:0000232 + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of erythrocyte differentiation. + down regulation of erythrocyte differentiation + down-regulation of erythrocyte differentiation + downregulation of erythrocyte differentiation + negative regulation of RBC differentiation + negative regulation of red blood cell differentiation + inhibition of erythrocyte differentiation + biological_process + GO:0045647 + negative regulation of erythrocyte differentiation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of erythrocyte differentiation. + GOC:go_curators + + + + + negative regulation of RBC differentiation + CL:0000232 + + + + + negative regulation of red blood cell differentiation + CL:0000232 + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation. + positive regulation of RBC differentiation + positive regulation of red blood cell differentiation + up regulation of erythrocyte differentiation + up-regulation of erythrocyte differentiation + upregulation of erythrocyte differentiation + activation of erythrocyte differentiation + stimulation of erythrocyte differentiation + biological_process + GO:0045648 + positive regulation of erythrocyte differentiation + + + + + Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation. + GOC:go_curators + + + + + positive regulation of RBC differentiation + CL:0000232 + + + + + positive regulation of red blood cell differentiation + CL:0000232 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of macrophage differentiation. + biological_process + GO:0045649 + regulation of macrophage differentiation + + + + + Any process that modulates the frequency, rate or extent of macrophage differentiation. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage differentiation. + down regulation of macrophage differentiation + down-regulation of macrophage differentiation + downregulation of macrophage differentiation + inhibition of macrophage differentiation + biological_process + GO:0045650 + negative regulation of macrophage differentiation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage differentiation. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of macrophage differentiation. + up regulation of macrophage differentiation + up-regulation of macrophage differentiation + upregulation of macrophage differentiation + activation of macrophage differentiation + stimulation of macrophage differentiation + biological_process + GO:0045651 + positive regulation of macrophage differentiation + + + + + Any process that activates or increases the frequency, rate or extent of macrophage differentiation. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of neuron differentiation. + biological_process + GO:0045664 + regulation of neuron differentiation + + + + + Any process that modulates the frequency, rate or extent of neuron differentiation. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation. + down regulation of neuron differentiation + down-regulation of neuron differentiation + downregulation of neuron differentiation + inhibition of neuron differentiation + biological_process + GO:0045665 + negative regulation of neuron differentiation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of neuron differentiation. + up regulation of neuron differentiation + up-regulation of neuron differentiation + upregulation of neuron differentiation + activation of neuron differentiation + stimulation of neuron differentiation + biological_process + GO:0045666 + positive regulation of neuron differentiation + + + + + Any process that activates or increases the frequency, rate or extent of neuron differentiation. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of osteoblast differentiation. + biological_process + GO:0045667 + regulation of osteoblast differentiation + + + + + Any process that modulates the frequency, rate or extent of osteoblast differentiation. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of osteoblast differentiation. + down regulation of osteoblast differentiation + down-regulation of osteoblast differentiation + downregulation of osteoblast differentiation + inhibition of osteoblast differentiation + biological_process + GO:0045668 + negative regulation of osteoblast differentiation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of osteoblast differentiation. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of osteoblast differentiation. + up regulation of osteoblast differentiation + up-regulation of osteoblast differentiation + upregulation of osteoblast differentiation + activation of osteoblast differentiation + stimulation of osteoblast differentiation + biological_process + GO:0045669 + positive regulation of osteoblast differentiation + + + + + Any process that activates or increases the frequency, rate or extent of osteoblast differentiation. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of epidermis development. + regulation of epidermal development + biological_process + regulation of hypodermis development + GO:0045682 + regulation of epidermis development + + + + + Any process that modulates the frequency, rate or extent of epidermis development. + GOC:go_curators + + + + + regulation of hypodermis development + GOC:kmv + GOC:rk + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of epidermis development. + down regulation of epidermis development + down-regulation of epidermis development + downregulation of epidermis development + negative regulation of epidermal development + inhibition of epidermis development + biological_process + negative regulation of hypodermis development + GO:0045683 + negative regulation of epidermis development + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of epidermis development. + GOC:go_curators + + + + + negative regulation of hypodermis development + GOC:kmv + GOC:rk + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of epidermis development. + positive regulation of epidermal development + up regulation of epidermis development + up-regulation of epidermis development + upregulation of epidermis development + activation of epidermis development + stimulation of epidermis development + biological_process + positive regulation of hypodermis development + GO:0045684 + positive regulation of epidermis development + + + + + Any process that activates or increases the frequency, rate or extent of epidermis development. + GOC:go_curators + + + + + positive regulation of hypodermis development + GOC:kmv + GOC:rk + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of glia cell differentiation. + regulation of glia cell differentiation + regulation of neuroglia differentiation + biological_process + GO:0045685 + regulation of glial cell differentiation + + + + + Any process that modulates the frequency, rate or extent of glia cell differentiation. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of glia cell differentiation. + down regulation of glial cell differentiation + down-regulation of glial cell differentiation + downregulation of glial cell differentiation + negative regulation of glia cell differentiation + negative regulation of neuroglia differentiation + inhibition of glial cell differentiation + biological_process + GO:0045686 + negative regulation of glial cell differentiation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of glia cell differentiation. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of glia cell differentiation. + positive regulation of glia cell differentiation + positive regulation of neuroglia differentiation + up regulation of glial cell differentiation + up-regulation of glial cell differentiation + upregulation of glial cell differentiation + activation of glial cell differentiation + stimulation of glial cell differentiation + biological_process + GO:0045687 + positive regulation of glial cell differentiation + + + + + Any process that activates or increases the frequency, rate or extent of glia cell differentiation. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen. + down regulation of glycogen biosynthetic process + down-regulation of glycogen biosynthetic process + downregulation of glycogen biosynthetic process + negative regulation of glycogen anabolism + negative regulation of glycogen biosynthesis + negative regulation of glycogen formation + negative regulation of glycogen synthesis + inhibition of glycogen biosynthetic process + biological_process + GO:0045719 + negative regulation of glycogen biosynthetic process + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of gluconeogenesis. + down regulation of gluconeogenesis + down-regulation of gluconeogenesis + downregulation of gluconeogenesis + inhibition of gluconeogenesis + biological_process + GO:0045721 + negative regulation of gluconeogenesis + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of gluconeogenesis. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of gluconeogenesis. + up regulation of gluconeogenesis + up-regulation of gluconeogenesis + upregulation of gluconeogenesis + activation of gluconeogenesis + stimulation of gluconeogenesis + biological_process + GO:0045722 + positive regulation of gluconeogenesis + + + + + Any process that activates or increases the frequency, rate or extent of gluconeogenesis. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the formation of a cilium. + positive regulation of flagellum assembly + up regulation of cilium assembly + up-regulation of cilium assembly + upregulation of cilium assembly + activation of cilium assembly + stimulation of cilium assembly + biological_process + positive regulation of flagellum biogenesis + GO:0045724 + positive regulation of cilium assembly + + + + + Any process that activates or increases the frequency, rate or extent of the formation of a cilium. + GOC:cilia + GOC:go_curators + + + + + positive regulation of flagellum biogenesis + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen. + positive regulation of glycogen anabolism + positive regulation of glycogen biosynthesis + positive regulation of glycogen formation + positive regulation of glycogen synthesis + up regulation of glycogen biosynthetic process + up-regulation of glycogen biosynthetic process + upregulation of glycogen biosynthetic process + activation of glycogen biosynthetic process + stimulation of glycogen biosynthetic process + biological_process + GO:0045725 + positive regulation of glycogen biosynthetic process + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. + https://github.com/geneontology/go-ontology/issues/23112 + GO:1903364 + GO:2000600 + positive regulation of cellular protein breakdown + positive regulation of cellular protein catabolic process + positive regulation of cellular protein catabolism + positive regulation of cellular protein degradation + positive regulation of protein breakdown + positive regulation of protein catabolism + positive regulation of protein degradation + up regulation of cellular protein breakdown + up regulation of cellular protein catabolic process + up regulation of cellular protein catabolism + up regulation of cellular protein degradation + up regulation of protein catabolic process + up-regulation of cellular protein breakdown + up-regulation of cellular protein catabolic process + up-regulation of cellular protein catabolism + up-regulation of cellular protein degradation + up-regulation of protein catabolic process + upregulation of cellular protein breakdown + upregulation of cellular protein catabolic process + upregulation of cellular protein catabolism + upregulation of cellular protein degradation + upregulation of protein catabolic process + activation of cellular protein breakdown + activation of cellular protein catabolic process + activation of cellular protein catabolism + activation of cellular protein degradation + activation of protein catabolic process + positive regulation of cyclin breakdown + positive regulation of cyclin catabolic process + positive regulation of cyclin catabolism + positive regulation of cyclin degradation + positive regulation of degradation of cyclin + stimulation of protein catabolic process + biological_process + GO:0045732 + positive regulation of protein catabolic process + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds. + GOC:go_curators + + + + + positive regulation of cellular protein breakdown + GOC:TermGenie + + + + + positive regulation of cellular protein catabolism + GOC:TermGenie + + + + + positive regulation of cellular protein degradation + GOC:TermGenie + + + + + up regulation of cellular protein breakdown + GOC:TermGenie + + + + + up regulation of cellular protein catabolic process + GOC:TermGenie + + + + + up regulation of cellular protein catabolism + GOC:TermGenie + + + + + up regulation of cellular protein degradation + GOC:TermGenie + + + + + up-regulation of cellular protein breakdown + GOC:TermGenie + + + + + up-regulation of cellular protein catabolic process + GOC:TermGenie + + + + + up-regulation of cellular protein catabolism + GOC:TermGenie + + + + + up-regulation of cellular protein degradation + GOC:TermGenie + + + + + upregulation of cellular protein breakdown + GOC:TermGenie + + + + + upregulation of cellular protein catabolic process + GOC:TermGenie + + + + + upregulation of cellular protein catabolism + GOC:TermGenie + + + + + upregulation of cellular protein degradation + GOC:TermGenie + + + + + activation of cellular protein breakdown + GOC:TermGenie + + + + + activation of cellular protein catabolic process + GOC:TermGenie + + + + + activation of cellular protein catabolism + GOC:TermGenie + + + + + activation of cellular protein degradation + GOC:TermGenie + + + + + positive regulation of cyclin breakdown + GOC:obol + + + + + positive regulation of cyclin catabolism + GOC:obol + + + + + positive regulation of cyclin degradation + GOC:obol + + + + + positive regulation of degradation of cyclin + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of G protein-coupled receptor signaling pathway. + down regulation of G-protein coupled receptor protein signaling pathway + down-regulation of G-protein coupled receptor protein signaling pathway + downregulation of G-protein coupled receptor protein signaling pathway + negative regulation of G protein coupled receptor protein signaling pathway + negative regulation of G protein coupled receptor protein signalling pathway + negative regulation of G-protein coupled receptor protein signaling pathway + negative regulation of G-protein coupled receptor protein signalling pathway + negative regulation of G-protein-coupled receptor protein signalling pathway + negative regulation of GPCR protein signaling pathway + negative regulation of GPCR protein signalling pathway + inhibition of G-protein coupled receptor protein signaling pathway + biological_process + GO:0045744 + negative regulation of G protein-coupled receptor signaling pathway + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of G protein-coupled receptor signaling pathway. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of G protein-coupled receptor signaling pathway activity. + positive regulation of G protein coupled receptor protein signaling pathway + positive regulation of G protein coupled receptor protein signalling pathway + positive regulation of G-protein coupled receptor protein signaling pathway + positive regulation of G-protein coupled receptor protein signalling pathway + positive regulation of G-protein-coupled receptor protein signaling pathway + positive regulation of G-protein-coupled receptor protein signalling pathway + positive regulation of GPCR protein signaling pathway + positive regulation of GPCR protein signalling pathway + up regulation of G-protein coupled receptor protein signaling pathway + up-regulation of G-protein coupled receptor protein signaling pathway + upregulation of G-protein coupled receptor protein signaling pathway + activation of G-protein coupled receptor protein signaling pathway + stimulation of G-protein coupled receptor protein signaling pathway + biological_process + GO:0045745 + positive regulation of G protein-coupled receptor signaling pathway + + + + + Any process that activates or increases the frequency, rate or extent of G protein-coupled receptor signaling pathway activity. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amino acid. + down regulation of amino acid metabolic process + down-regulation of amino acid metabolic process + downregulation of amino acid metabolic process + negative regulation of amino acid metabolism + inhibition of amino acid metabolic process + biological_process + GO:0045763 + negative regulation of cellular amino acid metabolic process + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amino acid. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amino acid. + positive regulation of amino acid metabolism + up regulation of amino acid metabolic process + up-regulation of amino acid metabolic process + upregulation of amino acid metabolic process + activation of amino acid metabolic process + stimulation of amino acid metabolic process + biological_process + GO:0045764 + positive regulation of cellular amino acid metabolic process + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amino acid. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of angiogenesis. + biological_process + GO:0045765 + regulation of angiogenesis + + + + + Any process that modulates the frequency, rate or extent of angiogenesis. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases angiogenesis. + up regulation of angiogenesis + up-regulation of angiogenesis + upregulation of angiogenesis + activation of angiogenesis + stimulation of angiogenesis + biological_process + GO:0045766 + positive regulation of angiogenesis + + + + + Any process that activates or increases angiogenesis. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of asymmetric cell division. + down regulation of asymmetric cell division + down-regulation of asymmetric cell division + downregulation of asymmetric cell division + inhibition of asymmetric cell division + biological_process + GO:0045769 + negative regulation of asymmetric cell division + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of asymmetric cell division. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of asymmetric cell division. + up regulation of asymmetric cell division + up-regulation of asymmetric cell division + upregulation of asymmetric cell division + activation of asymmetric cell division + stimulation of asymmetric cell division + biological_process + GO:0045770 + positive regulation of asymmetric cell division + + + + + Any process that activates or increases the frequency, rate or extent of asymmetric cell division. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance. + positive regulation of bone biosynthesis + positive regulation of bone formation + up regulation of ossification + up-regulation of ossification + upregulation of ossification + activation of ossification + stimulation of ossification + biological_process + GO:0045778 + positive regulation of ossification + + + + + Any process that activates or increases the frequency, rate or extent of ossification, the formation of bone or of a bony substance or the conversion of fibrous tissue or of cartilage into bone or a bony substance. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of cell adhesion. + up regulation of cell adhesion + up-regulation of cell adhesion + upregulation of cell adhesion + activation of cell adhesion + stimulation of cell adhesion + biological_process + GO:0045785 + positive regulation of cell adhesion + + + + + Any process that activates or increases the frequency, rate or extent of cell adhesion. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle. + down regulation of progression through cell cycle + down-regulation of progression through cell cycle + downregulation of progression through cell cycle + negative regulation of cell cycle progression + negative regulation of progression through cell cycle + inhibition of progression through cell cycle + biological_process + GO:0045786 + negative regulation of cell cycle + + + + + Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle. + GOC:dph + GOC:go_curators + GOC:tb + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the rate or extent of progression through the cell cycle. + positive regulation of cell cycle progression + positive regulation of progression through cell cycle + up regulation of progression through cell cycle + up-regulation of progression through cell cycle + upregulation of progression through cell cycle + activation of progression through cell cycle + stimulation of progression through cell cycle + biological_process + GO:0045787 + positive regulation of cell cycle + + + + + Any process that activates or increases the rate or extent of progression through the cell cycle. + GOC:go_curators + + + + + positive regulation of progression through cell cycle + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of eclosion. + down regulation of eclosion + down-regulation of eclosion + downregulation of eclosion + inhibition of eclosion + biological_process + GO:0045804 + negative regulation of eclosion + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of eclosion. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of eclosion. + up regulation of eclosion + up-regulation of eclosion + upregulation of eclosion + activation of eclosion + stimulation of eclosion + biological_process + GO:0045805 + positive regulation of eclosion + + + + + Any process that activates or increases the frequency, rate or extent of eclosion. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen. + down regulation of glycogen catabolic process + down-regulation of glycogen catabolic process + downregulation of glycogen catabolic process + negative regulation of glycogen breakdown + negative regulation of glycogen catabolism + negative regulation of glycogen degradation + negative regulation of glycogenolysis + inhibition of glycogen catabolic process + biological_process + GO:0045818 + negative regulation of glycogen catabolic process + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen. + GOC:go_curators + + + + + negative regulation of glycogenolysis + GOC:sl + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen. + positive regulation of glycogen breakdown + positive regulation of glycogen catabolism + positive regulation of glycogen degradation + positive regulation of glycogenolysis + up regulation of glycogen catabolic process + up-regulation of glycogen catabolic process + upregulation of glycogen catabolic process + activation of glycogen catabolic process + stimulation of glycogen catabolic process + biological_process + GO:0045819 + positive regulation of glycogen catabolic process + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen. + GOC:go_curators + + + + + positive regulation of glycogenolysis + GOC:sl + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction. + down regulation of heart contraction + down-regulation of heart contraction + downregulation of heart contraction + inhibition of heart contraction + biological_process + negative regulation of cardiac contraction + GO:0045822 + negative regulation of heart contraction + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of heart contraction. + positive regulation of cardiac contraction + up regulation of heart contraction + up-regulation of heart contraction + upregulation of heart contraction + activation of heart contraction + stimulation of heart contraction + biological_process + GO:0045823 + positive regulation of heart contraction + + + + + Any process that activates or increases the frequency, rate or extent of heart contraction. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipids. + down regulation of lipid metabolic process + down-regulation of lipid metabolic process + downregulation of lipid metabolic process + negative regulation of lipid metabolism + inhibition of lipid metabolic process + biological_process + GO:0045833 + negative regulation of lipid metabolic process + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipids. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipids. + positive regulation of lipid metabolism + up regulation of lipid metabolic process + up-regulation of lipid metabolic process + upregulation of lipid metabolic process + activation of lipid metabolic process + stimulation of lipid metabolic process + biological_process + GO:0045834 + positive regulation of lipid metabolic process + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipids. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis. + down regulation of meiosis + down-regulation of meiosis + downregulation of meiosis + negative regulation of meiosis + inhibition of meiosis + biological_process + GO:0045835 + negative regulation of meiotic nuclear division + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of meiosis. + positive regulation of meiosis + up regulation of meiosis + up-regulation of meiosis + upregulation of meiosis + activation of meiosis + stimulation of meiosis + biological_process + GO:0045836 + positive regulation of meiotic nuclear division + + + + + Any process that activates or increases the frequency, rate or extent of meiosis. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle development. + down regulation of striated muscle development + down-regulation of striated muscle development + downregulation of striated muscle development + inhibition of striated muscle development + biological_process + GO:0045843 + negative regulation of striated muscle tissue development + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle development. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of striated muscle development. + up regulation of striated muscle development + up-regulation of striated muscle development + upregulation of striated muscle development + activation of striated muscle development + stimulation of striated muscle development + biological_process + GO:0045844 + positive regulation of striated muscle tissue development + + + + + Any process that activates or increases the frequency, rate or extent of striated muscle development. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of protein kinase activity. + biological_process + GO:0045859 + regulation of protein kinase activity + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate or extent of protein kinase activity. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of protein kinase activity. + up regulation of protein kinase activity + up-regulation of protein kinase activity + upregulation of protein kinase activity + stimulation of protein kinase activity + biological_process + GO:0045860 + positive regulation of protein kinase activity + + + + + Any process that activates or increases the frequency, rate or extent of protein kinase activity. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate. + down regulation of carbohydrate metabolic process + down-regulation of carbohydrate metabolic process + downregulation of carbohydrate metabolic process + negative regulation of carbohydrate metabolism + inhibition of carbohydrate metabolic process + biological_process + GO:0045912 + negative regulation of carbohydrate metabolic process + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate. + positive regulation of carbohydrate metabolism + up regulation of carbohydrate metabolic process + up-regulation of carbohydrate metabolic process + upregulation of carbohydrate metabolic process + activation of carbohydrate metabolic process + stimulation of carbohydrate metabolic process + biological_process + GO:0045913 + positive regulation of carbohydrate metabolic process + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catecholamine. + down regulation of catecholamine metabolic process + down-regulation of catecholamine metabolic process + downregulation of catecholamine metabolic process + negative regulation of catecholamine metabolism + inhibition of catecholamine metabolic process + biological_process + GO:0045914 + negative regulation of catecholamine metabolic process + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catecholamine. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catecholamine. + positive regulation of catecholamine metabolism + up regulation of catecholamine metabolic process + up-regulation of catecholamine metabolic process + upregulation of catecholamine metabolic process + activation of catecholamine metabolic process + stimulation of catecholamine metabolic process + biological_process + GO:0045915 + positive regulation of catecholamine metabolic process + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catecholamine. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of exocytosis. + down regulation of exocytosis + down-regulation of exocytosis + downregulation of exocytosis + inhibition of exocytosis + biological_process + GO:0045920 + negative regulation of exocytosis + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of exocytosis. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of exocytosis. + up regulation of exocytosis + up-regulation of exocytosis + upregulation of exocytosis + activation of exocytosis + stimulation of exocytosis + biological_process + GO:0045921 + positive regulation of exocytosis + + + + + Any process that activates or increases the frequency, rate or extent of exocytosis. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism. + down regulation of growth + down-regulation of growth + downregulation of growth + inhibition of growth + biological_process + GO:0045926 + negative regulation of growth + + + + + Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism. + up regulation of growth + up-regulation of growth + upregulation of growth + activation of growth + stimulation of growth + biological_process + GO:0045927 + positive regulation of growth + + + + + Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone. + down regulation of juvenile hormone metabolic process + down-regulation of juvenile hormone metabolic process + downregulation of juvenile hormone metabolic process + negative regulation of juvenile hormone metabolism + inhibition of juvenile hormone metabolic process + biological_process + GO:0045928 + negative regulation of juvenile hormone metabolic process + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone. + positive regulation of juvenile hormone metabolism + up regulation of juvenile hormone metabolic process + up-regulation of juvenile hormone metabolic process + upregulation of juvenile hormone metabolic process + activation of juvenile hormone metabolic process + stimulation of juvenile hormone metabolic process + biological_process + GO:0045929 + positive regulation of juvenile hormone metabolic process + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of muscle contraction. + down regulation of muscle contraction + down-regulation of muscle contraction + downregulation of muscle contraction + inhibition of muscle contraction + biological_process + GO:0045932 + negative regulation of muscle contraction + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of muscle contraction. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of muscle contraction. + up regulation of muscle contraction + up-regulation of muscle contraction + upregulation of muscle contraction + activation of muscle contraction + stimulation of muscle contraction + biological_process + GO:0045933 + positive regulation of muscle contraction + + + + + Any process that activates or increases the frequency, rate or extent of muscle contraction. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates. + down regulation of phosphate metabolic process + down-regulation of phosphate metabolic process + downregulation of phosphate metabolic process + negative regulation of phosphate metabolism + inhibition of phosphate metabolic process + biological_process + GO:0045936 + negative regulation of phosphate metabolic process + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates. + positive regulation of phosphate metabolism + up regulation of phosphate metabolic process + up-regulation of phosphate metabolic process + upregulation of phosphate metabolic process + activation of phosphate metabolic process + stimulation of phosphate metabolic process + biological_process + GO:0045937 + positive regulation of phosphate metabolic process + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the duration or quality of sleep, a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals. + positive regulation of sleep + up regulation of circadian sleep/wake cycle, sleep + up-regulation of circadian sleep/wake cycle, sleep + upregulation of circadian sleep/wake cycle, sleep + activation of circadian sleep/wake cycle, sleep + stimulation of circadian sleep/wake cycle, sleep + biological_process + GO:0045938 + positive regulation of circadian sleep/wake cycle, sleep + + + + + Any process that activates or increases the duration or quality of sleep, a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving steroids. + down regulation of steroid metabolic process + down-regulation of steroid metabolic process + downregulation of steroid metabolic process + negative regulation of steroid metabolism + inhibition of steroid metabolic process + biological_process + GO:0045939 + negative regulation of steroid metabolic process + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving steroids. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving steroids. + positive regulation of steroid metabolism + up regulation of steroid metabolic process + up-regulation of steroid metabolic process + upregulation of steroid metabolic process + activation of steroid metabolic process + stimulation of steroid metabolic process + biological_process + GO:0045940 + positive regulation of steroid metabolic process + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving steroids. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone. + regulation of juvenile hormone breakdown + regulation of juvenile hormone catabolism + regulation of juvenile hormone degradation + biological_process + GO:0045952 + regulation of juvenile hormone catabolic process + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving dopamine. + down regulation of dopamine metabolic process + down-regulation of dopamine metabolic process + downregulation of dopamine metabolic process + negative regulation of dopamine metabolism + inhibition of dopamine metabolic process + biological_process + GO:0045963 + negative regulation of dopamine metabolic process + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving dopamine. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving dopamine. + positive regulation of dopamine metabolism + up regulation of dopamine metabolic process + up-regulation of dopamine metabolic process + upregulation of dopamine metabolic process + activation of dopamine metabolic process + stimulation of dopamine metabolic process + biological_process + GO:0045964 + positive regulation of dopamine metabolic process + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving dopamine. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone. + down regulation of juvenile hormone biosynthetic process + down-regulation of juvenile hormone biosynthetic process + downregulation of juvenile hormone biosynthetic process + negative regulation of juvenile hormone anabolism + negative regulation of juvenile hormone biosynthesis + negative regulation of juvenile hormone formation + negative regulation of juvenile hormone synthesis + inhibition of juvenile hormone biosynthetic process + biological_process + GO:0045968 + negative regulation of juvenile hormone biosynthetic process + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone. + positive regulation of juvenile hormone anabolism + positive regulation of juvenile hormone biosynthesis + positive regulation of juvenile hormone formation + positive regulation of juvenile hormone synthesis + up regulation of juvenile hormone biosynthetic process + up-regulation of juvenile hormone biosynthetic process + upregulation of juvenile hormone biosynthetic process + activation of juvenile hormone biosynthetic process + stimulation of juvenile hormone biosynthetic process + biological_process + GO:0045969 + positive regulation of juvenile hormone biosynthetic process + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone. + down regulation of juvenile hormone catabolic process + down-regulation of juvenile hormone catabolic process + downregulation of juvenile hormone catabolic process + negative regulation of juvenile hormone breakdown + negative regulation of juvenile hormone catabolism + negative regulation of juvenile hormone degradation + inhibition of juvenile hormone catabolic process + biological_process + GO:0045970 + negative regulation of juvenile hormone catabolic process + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone. + positive regulation of juvenile hormone breakdown + positive regulation of juvenile hormone catabolism + positive regulation of juvenile hormone degradation + up regulation of juvenile hormone catabolic process + up-regulation of juvenile hormone catabolic process + upregulation of juvenile hormone catabolic process + activation of juvenile hormone catabolic process + stimulation of juvenile hormone catabolic process + biological_process + GO:0045971 + positive regulation of juvenile hormone catabolic process + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of juvenile hormone. + down regulation of juvenile hormone secretion + down-regulation of juvenile hormone secretion + downregulation of juvenile hormone secretion + inhibition of juvenile hormone secretion + biological_process + GO:0045972 + negative regulation of juvenile hormone secretion + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of juvenile hormone. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the regulated release of juvenile hormone. + up regulation of juvenile hormone secretion + up-regulation of juvenile hormone secretion + upregulation of juvenile hormone secretion + activation of juvenile hormone secretion + stimulation of juvenile hormone secretion + biological_process + GO:0045973 + positive regulation of juvenile hormone secretion + + + + + Any process that activates or increases the frequency, rate or extent of the regulated release of juvenile hormone. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle contraction. + down regulation of smooth muscle contraction + down-regulation of smooth muscle contraction + downregulation of smooth muscle contraction + inhibition of smooth muscle contraction + biological_process + smooth muscle relaxation + GO:0045986 + negative regulation of smooth muscle contraction + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle contraction. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of smooth muscle contraction. + up regulation of smooth muscle contraction + up-regulation of smooth muscle contraction + upregulation of smooth muscle contraction + activation of smooth muscle contraction + stimulation of smooth muscle contraction + biological_process + GO:0045987 + positive regulation of smooth muscle contraction + + + + + Any process that activates or increases the frequency, rate or extent of smooth muscle contraction. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle contraction. + down regulation of striated muscle contraction + down-regulation of striated muscle contraction + downregulation of striated muscle contraction + inhibition of striated muscle contraction + biological_process + GO:0045988 + negative regulation of striated muscle contraction + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle contraction. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of striated muscle contraction. + up regulation of striated muscle contraction + up-regulation of striated muscle contraction + upregulation of striated muscle contraction + activation of striated muscle contraction + stimulation of striated muscle contraction + biological_process + GO:0045989 + positive regulation of striated muscle contraction + + + + + Any process that activates or increases the frequency, rate or extent of striated muscle contraction. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of embryonic development. + down regulation of embryonic development + down-regulation of embryonic development + downregulation of embryonic development + inhibition of embryonic development + biological_process + GO:0045992 + negative regulation of embryonic development + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of embryonic development. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of embryonic development. + biological_process + GO:0045995 + regulation of embryonic development + + + + + Any process that modulates the frequency, rate or extent of embryonic development. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the duration or quality of non-rapid eye movement (NREM) sleep. + positive regulation of non-REM sleep + up regulation of circadian sleep/wake cycle, non-REM sleep + up-regulation of circadian sleep/wake cycle, non-REM sleep + upregulation of circadian sleep/wake cycle, non-REM sleep + activation of circadian sleep/wake cycle, non-REM sleep + stimulation of circadian sleep/wake cycle, non-REM sleep + biological_process + GO:0046010 + positive regulation of circadian sleep/wake cycle, non-REM sleep + + + + + Any process that activates or increases the duration or quality of non-rapid eye movement (NREM) sleep. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of resting T cell proliferation. + regulation of T lymphocyte homeostatic proliferation + regulation of T-cell homeostatic proliferation + regulation of T-lymphocyte homeostatic proliferation + regulation of resting T cell proliferation + biological_process + GO:0046013 + regulation of T cell homeostatic proliferation + + + + + Any process that modulates the frequency, rate or extent of resting T cell proliferation. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the rate or extent of resting T cell proliferation. + down regulation of T cell homeostatic proliferation + down-regulation of T cell homeostatic proliferation + downregulation of T cell homeostatic proliferation + negative regulation of T lymphocyte homeostatic proliferation + negative regulation of T-cell homeostatic proliferation + negative regulation of T-lymphocyte homeostatic proliferation + negative regulation of resting T cell proliferation + inhibition of T cell homeostatic proliferation + biological_process + GO:0046014 + negative regulation of T cell homeostatic proliferation + + + + + Any process that stops, prevents or reduces the rate or extent of resting T cell proliferation. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of aldehydes, any organic compound with the formula R-CH=O. + aldehyde anabolism + aldehyde biosynthesis + aldehyde formation + aldehyde synthesis + biological_process + GO:0046184 + aldehyde biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of aldehydes, any organic compound with the formula R-CH=O. + GOC:ai + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of aldehydes, any organic compound with the formula R-CH=O. + aldehyde breakdown + aldehyde catabolism + aldehyde degradation + biological_process + GO:0046185 + aldehyde catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of aldehydes, any organic compound with the formula R-CH=O. + GOC:ai + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring. + phenol-containing compound anabolism + phenol-containing compound biosynthesis + phenol-containing compound formation + phenol-containing compound synthesis + biological_process + GO:0046189 + phenol-containing compound biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring. + GOC:ai + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. + monosaccharide anabolism + monosaccharide biosynthesis + monosaccharide formation + monosaccharide synthesis + biological_process + GO:0046364 + monosaccharide biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. + monosaccharide breakdown + monosaccharide catabolism + monosaccharide degradation + biological_process + GO:0046365 + monosaccharide catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups. + carboxylic acid anabolism + carboxylic acid biosynthesis + carboxylic acid formation + carboxylic acid synthesis + biological_process + GO:0046394 + carboxylic acid biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups. + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups. + carboxylic acid breakdown + carboxylic acid catabolism + carboxylic acid degradation + biological_process + GO:0046395 + carboxylic acid catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups. + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings). + heterocycle metabolism + biological_process + GO:0046483 + + heterocycle metabolic process + + + + + The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings). + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + The specialization of organization of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light. An example of this process is found in Drosophila melanogaster. + GO:0007467 + biological_process + GO:0046530 + photoreceptor cell differentiation + + + + + The specialization of organization of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light. An example of this process is found in Drosophila melanogaster. + GOC:ai + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster. + GO:0045673 + regulation of photoreceptor differentiation + biological_process + GO:0046532 + regulation of photoreceptor cell differentiation + + + + + Any process that modulates the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster. + GO:0045674 + down regulation of photoreceptor cell differentiation + down regulation of photoreceptor differentiation + down-regulation of photoreceptor cell differentiation + down-regulation of photoreceptor differentiation + downregulation of photoreceptor cell differentiation + downregulation of photoreceptor differentiation + negative regulation of photoreceptor differentiation + inhibition of photoreceptor cell differentiation + inhibition of photoreceptor differentiation + biological_process + GO:0046533 + negative regulation of photoreceptor cell differentiation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster. + GO:0045675 + positive regulation of photoreceptor differentiation + up regulation of photoreceptor cell differentiation + up regulation of photoreceptor differentiation + up-regulation of photoreceptor cell differentiation + up-regulation of photoreceptor differentiation + upregulation of photoreceptor cell differentiation + upregulation of photoreceptor differentiation + activation of photoreceptor cell differentiation + activation of photoreceptor differentiation + stimulation of photoreceptor cell differentiation + stimulation of photoreceptor differentiation + biological_process + GO:0046534 + positive regulation of photoreceptor cell differentiation + + + + + Any process that activates or increases the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster. + GOC:go_curators + + + + + + + + + + + The regulated release of saliva from the salivary glands. In man, the saliva is a turbid and slightly viscous fluid, generally of an alkaline reaction, and is secreted by the parotid, submaxillary, and sublingual glands. In the mouth the saliva is mixed with the secretion from the buccal glands. In man and many animals, saliva is an important digestive fluid on account of the presence of the peculiar enzyme, ptyalin. + Wikipedia:Salivation + salivation + biological_process + GO:0046541 + saliva secretion + + + + + The regulated release of saliva from the salivary glands. In man, the saliva is a turbid and slightly viscous fluid, generally of an alkaline reaction, and is secreted by the parotid, submaxillary, and sublingual glands. In the mouth the saliva is mixed with the secretion from the buccal glands. In man and many animals, saliva is an important digestive fluid on account of the presence of the peculiar enzyme, ptyalin. + GOC:curators + UBERON:0001836 + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the primary female sexual characteristics over time, from their formation to the mature structure. The primary female sexual characteristics are the ovaries, and they develop in response to sex hormone secretion. + biological_process + GO:0046545 + development of primary female sexual characteristics + + + + + The process whose specific outcome is the progression of the primary female sexual characteristics over time, from their formation to the mature structure. The primary female sexual characteristics are the ovaries, and they develop in response to sex hormone secretion. + GOC:ai + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the primary male sexual characteristics over time, from their formation to the mature structures. The primary male sexual characteristics are the testes, and they develop in response to sex hormone secretion. + biological_process + GO:0046546 + development of primary male sexual characteristics + + + + + The process whose specific outcome is the progression of the primary male sexual characteristics over time, from their formation to the mature structures. The primary male sexual characteristics are the testes, and they develop in response to sex hormone secretion. + GOC:ai + + + + + + + + + + + + + + + + + + + + + + + + + + Development of a rod cell, one of the sensory cells in the eye that reacts to the presence of light. Rod cells contain the photopigment rhodopsin or porphyropsin and are responsible for vision in dim light. + biological_process + GO:0046548 + retinal rod cell development + + + + + Development of a rod cell, one of the sensory cells in the eye that reacts to the presence of light. Rod cells contain the photopigment rhodopsin or porphyropsin and are responsible for vision in dim light. + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + + + + + + + Development of a cone cell, one of the sensory cells in the eye that reacts to the presence of light. Cone cells contain the photopigment iodopsin or cyanopsin and are responsible for photopic (daylight) vision. + biological_process + GO:0046549 + retinal cone cell development + + + + + Development of a cone cell, one of the sensory cells in the eye that reacts to the presence of light. Cone cells contain the photopigment iodopsin or cyanopsin and are responsible for photopic (daylight) vision. + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of growth of an organ of an organism. + biological_process + GO:0046620 + regulation of organ growth + + + + + Any process that modulates the frequency, rate or extent of growth of an organ of an organism. + GOC:bf + GOC:tb + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism. + biological_process + GO:0046621 + negative regulation of organ growth + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism. + GOC:bf + GOC:tb + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of growth of an organ of an organism. + biological_process + GO:0046622 + positive regulation of organ growth + + + + + Any process that activates or increases the frequency, rate or extent of growth of an organ of an organism. + GOC:bf + GOC:tb + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of insulin receptor signaling. + regulation of insulin receptor signalling pathway + biological_process + GO:0046626 + regulation of insulin receptor signaling pathway + + + + + Any process that modulates the frequency, rate or extent of insulin receptor signaling. + GOC:bf + + + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of insulin receptor signaling. + down regulation of insulin receptor signaling pathway + down-regulation of insulin receptor signaling pathway + downregulation of insulin receptor signaling pathway + negative regulation of insulin receptor signalling pathway + inhibition of insulin receptor signaling pathway + biological_process + GO:0046627 + negative regulation of insulin receptor signaling pathway + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of insulin receptor signaling. + GOC:bf + + + + + + + + + + + + + + + + + + + + + + + + + Any process that increases the frequency, rate or extent of insulin receptor signaling. + positive regulation of insulin receptor signalling pathway + up regulation of insulin receptor signaling pathway + up-regulation of insulin receptor signaling pathway + upregulation of insulin receptor signaling pathway + activation of insulin receptor signaling pathway + stimulation of insulin receptor signaling pathway + biological_process + GO:0046628 + positive regulation of insulin receptor signaling pathway + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that increases the frequency, rate or extent of insulin receptor signaling. + GOC:bf + + + + + + + + + + + + + + + + + + + + A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor. + biological_process + GO:0046649 + lymphocyte activation + + + + + A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor. + GOC:mgi_curators + ISBN:0781735149 + + + + + + + + + + + + + + + + + + + + + The expansion of a lymphocyte population by cell division. + biological_process + GO:0046651 + lymphocyte proliferation + + + + + The expansion of a lymphocyte population by cell division. + GOC:ai + + + + + + + + + + + + + + + The establishment of the sex of a female organism by physical differentiation. + biological_process + GO:0046660 + female sex differentiation + + + + + The establishment of the sex of a female organism by physical differentiation. + GOC:bf + + + + + + + + + + + + + + + The establishment of the sex of a male organism by physical differentiation. + biological_process + GO:0046661 + male sex differentiation + + + + + The establishment of the sex of a male organism by physical differentiation. + GOC:bf + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of insulin. + down regulation of insulin secretion + down-regulation of insulin secretion + downregulation of insulin secretion + inhibition of insulin secretion + biological_process + GO:0046676 + negative regulation of insulin secretion + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of insulin. + GOC:ai + + + + + + + + + + + + + + + + + Any process that contributes to the success of sperm fertilization in multiply-mated females. + Wikipedia:Sperm_competition + biological_process + GO:0046692 + sperm competition + + + + + Any process that contributes to the success of sperm fertilization in multiply-mated females. + PMID:10885514 + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings). + heterocycle breakdown + heterocycle catabolism + heterocycle degradation + biological_process + GO:0046700 + heterocycle catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings). + GOC:ai + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The cellular homeostatic process that preserves a muscle cell in a stable functional or structural state. + + muscle fiber maintenance + biological_process + muscle homeostasis + GO:0046716 + muscle cell cellular homeostasis + + + + + The cellular homeostatic process that preserves a muscle cell in a stable functional or structural state. + GOC:mah + PMID:3091429 + PMID:7781901 + + + + + muscle fiber maintenance + GOC:dph + GOC:tb + + + + + muscle homeostasis + GOC:dph + + + + + + + + + + + + + + + + + + + + The controlled release of acid by a cell or a tissue. + biological_process + GO:0046717 + acid secretion + + + + + The controlled release of acid by a cell or a tissue. + GOC:ai + + + + + + + + + + + + + + + + + + + + + + + + + + + The addition of tubulin heterodimers to one or both ends of a microtubule. + microtubule assembly + biological_process + microtubule formation + GO:0046785 + microtubule polymerization + + + + + The addition of tubulin heterodimers to one or both ends of a microtubule. + GOC:ai + GOC:go_curators + + + + + + + + + + + + + + + + + + + Binding to hydroxyapatite, the calcium phosphate mineral of formula Ca10(PO4)6(OH)2 found both in rocks of nonorganic origin and as a component of bone and dentin. + hydroxylapatite binding + molecular_function + GO:0046848 + hydroxyapatite binding + + + + + Binding to hydroxyapatite, the calcium phosphate mineral of formula Ca10(PO4)6(OH)2 found both in rocks of nonorganic origin and as a component of bone and dentin. + PMID:2438276 + + + + + hydroxylapatite binding + GOC:vk + + + + + + + + + + + + + + + + + + + Binding to a metal ion. + metal binding + heavy metal binding + molecular_function + GO:0046872 + + + + + metal ion binding + + + + + Binding to a metal ion. + GOC:ai + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the regulated release of saliva from a cell or a tissue. + biological_process + GO:0046877 + regulation of saliva secretion + + + + + Any process that modulates the frequency, rate or extent of the regulated release of saliva from a cell or a tissue. + GOC:ai + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the regulated release of saliva. + up regulation of saliva secretion + up-regulation of saliva secretion + upregulation of saliva secretion + activation of saliva secretion + stimulation of saliva secretion + biological_process + GO:0046878 + positive regulation of saliva secretion + + + + + Any process that activates or increases the frequency, rate or extent of the regulated release of saliva. + GOC:ai + + + + + + + + + + The regulated release of hormones, substances with a specific regulatory effect on a particular organ or group of cells. + biological_process + GO:0046879 + hormone secretion + + + + + The regulated release of hormones, substances with a specific regulatory effect on a particular organ or group of cells. + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the regulated release of a hormone from a cell. + biological_process + GO:0046883 + regulation of hormone secretion + + + + + Any process that modulates the frequency, rate or extent of the regulated release of a hormone from a cell. + GOC:ai + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones. + regulation of hormone anabolism + regulation of hormone biosynthesis + regulation of hormone formation + regulation of hormone synthesis + biological_process + GO:0046885 + regulation of hormone biosynthetic process + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones. + GOC:ai + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones. + positive regulation of hormone anabolism + positive regulation of hormone biosynthesis + positive regulation of hormone formation + positive regulation of hormone synthesis + up regulation of hormone biosynthetic process + up-regulation of hormone biosynthetic process + upregulation of hormone biosynthetic process + activation of hormone biosynthetic process + stimulation of hormone biosynthetic process + biological_process + GO:0046886 + positive regulation of hormone biosynthetic process + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones. + GOC:ai + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the regulated release of a hormone from a cell. + up regulation of hormone secretion + up-regulation of hormone secretion + upregulation of hormone secretion + activation of hormone secretion + stimulation of hormone secretion + biological_process + GO:0046887 + positive regulation of hormone secretion + + + + + Any process that activates or increases the frequency, rate or extent of the regulated release of a hormone from a cell. + GOC:ai + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a hormone from a cell. + down regulation of hormone secretion + down-regulation of hormone secretion + downregulation of hormone secretion + inhibition of hormone secretion + biological_process + GO:0046888 + negative regulation of hormone secretion + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a hormone from a cell. + GOC:ai + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids. + positive regulation of lipid anabolism + positive regulation of lipid biosynthesis + positive regulation of lipid formation + positive regulation of lipid synthesis + positive regulation of lipogenesis + up regulation of lipid biosynthetic process + up-regulation of lipid biosynthetic process + upregulation of lipid biosynthetic process + activation of lipid biosynthetic process + stimulation of lipid biosynthetic process + biological_process + GO:0046889 + positive regulation of lipid biosynthetic process + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids. + GOC:ai + + + + + positive regulation of lipogenesis + GOC:sl + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids. + regulation of lipid anabolism + regulation of lipid biosynthesis + regulation of lipid formation + regulation of lipid synthesis + regulation of lipogenesis + biological_process + GO:0046890 + regulation of lipid biosynthetic process + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids. + GOC:ai + + + + + regulation of lipogenesis + GOC:sl + + + + + + + + + The controlled release of a substance by a cell or a tissue. + biological_process + GO:0046903 + + secretion + + + + + The controlled release of a substance by a cell or a tissue. + GOC:ai + + + + + + + + + + + + + + + + + + + + The directed movement of substances within a cell. + jl + 2013-12-18T14:04:50Z + GO:1902582 + biological_process + single organism intracellular transport + single-organism intracellular transport + GO:0046907 + intracellular transport + + + + + The directed movement of substances within a cell. + GOC:ai + + + + + single organism intracellular transport + GOC:TermGenie + + + + + + + + + + + + + + + + + + + The directed movement of carboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-). + biological_process + GO:0046942 + carboxylic acid transport + + + + + The directed movement of carboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-). + GOC:ai + + + + + + + + + + + + + + + + + + + + + + + + The directed movement of a vesicle along a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination. + microtubule-based vesicle localization + biological_process + GO:0047496 + vesicle transport along microtubule + + + + + The directed movement of a vesicle along a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination. + GOC:ecd + GOC:rl + + + + + microtubule-based vesicle localization + GOC:rl + + + + + + + + + + + + + + + + + + + + Binding to a monosaccharide. Monosaccharides are the simplest carbohydrates; they are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H[CHOH]nC(=O)[CHOH]mH with three or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides. + molecular_function + GO:0048029 + monosaccharide binding + + + + + Binding to a monosaccharide. Monosaccharides are the simplest carbohydrates; they are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H[CHOH]nC(=O)[CHOH]mH with three or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides. + GOC:jid + + + + + + + + + + The process occurring in the embryo by which the anatomical structures of the post-embryonic eye are generated and organized. + biological_process + GO:0048048 + embryonic eye morphogenesis + + + + + The process occurring in the embryo by which the anatomical structures of the post-embryonic eye are generated and organized. + GOC:jid + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the corneal lens in the compound eye over time, from its formation to the mature structure. The corneal lens is a chitinous extracellular secretion of the four underlying cone cells and the pigment cells. + biological_process + GO:0048058 + compound eye corneal lens development + + + + + The process whose specific outcome is the progression of the corneal lens in the compound eye over time, from its formation to the mature structure. The corneal lens is a chitinous extracellular secretion of the four underlying cone cells and the pigment cells. + GOC:jid + + + + + + + + + The developmental process that results in the deposition of coloring matter in an organism, tissue or cell. + biological_process + pigmentation during development + GO:0048066 + developmental pigmentation + + + + + The developmental process that results in the deposition of coloring matter in an organism, tissue or cell. + ISBN:0582227089 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism. + regulation of pigmentation during development + biological_process + GO:0048070 + regulation of developmental pigmentation + + + + + Any process that modulates the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism. + GOC:dph + GOC:jid + GOC:tb + + + + + regulation of pigmentation during development + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + Any process that decreases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism. + down regulation of developmental pigmentation + down-regulation of developmental pigmentation + downregulation of developmental pigmentation + inhibition of pigmentation + biological_process + GO:0048086 + negative regulation of developmental pigmentation + + + + + Any process that decreases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism. + GOC:dph + GOC:jid + GOC:tb + + + + + down regulation of developmental pigmentation + GOC:dph + GOC:tb + + + + + down-regulation of developmental pigmentation + GOC:dph + GOC:tb + + + + + downregulation of developmental pigmentation + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + Any process that increases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism. + up regulation of developmental pigmentation + up-regulation of developmental pigmentation + upregulation of developmental pigmentation + activation of developmental pigmentation + stimulation of developmental pigmentation + biological_process + GO:0048087 + positive regulation of developmental pigmentation + + + + + Any process that increases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism. + GOC:dph + GOC:jid + GOC:tb + + + + + up regulation of developmental pigmentation + GOC:dph + + + + + up-regulation of developmental pigmentation + GOC:dph + GOC:tb + + + + + upregulation of developmental pigmentation + GOC:dph + GOC:tb + + + + + activation of developmental pigmentation + GOC:dph + GOC:tb + + + + + stimulation of developmental pigmentation + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + + + + + + A change in morphology and behavior of an astrocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. + biological_process + GO:0048143 + astrocyte activation + + + + + A change in morphology and behavior of an astrocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. + GOC:mgi_curators + PMID:10526094 + PMID:10695728 + PMID:12529254 + PMID:12580336 + PMID:9585813 + + + + + + + + + + + + + + + + + + + + The multiplication or reproduction of fibroblast cells, resulting in the expansion of the fibroblast population. + biological_process + GO:0048144 + fibroblast proliferation + + + + + The multiplication or reproduction of fibroblast cells, resulting in the expansion of the fibroblast population. + GOC:jid + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of multiplication or reproduction of fibroblast cells. + biological_process + GO:0048145 + regulation of fibroblast proliferation + + + + + Any process that modulates the frequency, rate or extent of multiplication or reproduction of fibroblast cells. + GOC:jid + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of multiplication or reproduction of fibroblast cells. + up regulation of fibroblast proliferation + up-regulation of fibroblast proliferation + upregulation of fibroblast proliferation + activation of fibroblast proliferation + stimulation of fibroblast proliferation + biological_process + GO:0048146 + positive regulation of fibroblast proliferation + + + + + Any process that activates or increases the frequency, rate or extent of multiplication or reproduction of fibroblast cells. + GOC:jid + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells. + down regulation of fibroblast proliferation + down-regulation of fibroblast proliferation + downregulation of fibroblast proliferation + inhibition of fibroblast proliferation + biological_process + GO:0048147 + negative regulation of fibroblast proliferation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells. + GOC:jid + + + + + + + + + + + + + + + + + + + + + The stage in oogenesis when many layers of follicle cells surround the oocyte. There is a yolk nucleus (Balbiani's Body) near the germinal vesicle. + mammalian oogenesis stage 5 + biological_process + GO:0048162 + multi-layer follicle stage + + + + + The stage in oogenesis when many layers of follicle cells surround the oocyte. There is a yolk nucleus (Balbiani's Body) near the germinal vesicle. + GOC:jid + GOC:mtg_sensu + ISBN:0198542771 + + + + + + + + + + + + + + + + + + + + + The stage in oogenesis when the antral spaces fuse to form a single antral space. The oocyte is suspended in the cumulus oophorous and the first polar body in the perivitelline space. + mammalian oogenesis stage 8 + biological_process + GO:0048165 + fused antrum stage + + + + + The stage in oogenesis when the antral spaces fuse to form a single antral space. The oocyte is suspended in the cumulus oophorous and the first polar body in the perivitelline space. + GOC:jid + GOC:mtg_sensu + ISBN:0198542771 + + + + + + + + + + + + + + + + + + + + The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles. + biological_process + Golgi-derived vesicle transport + GO:0048193 + + Golgi vesicle transport + + + + + The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles. + GOC:jid + ISBN:0716731363 + PMID:10219233 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which vesicles are directed to specific destination membranes during transport to, from or within the Golgi apparatus; mediated by the addition of specific coat proteins, including COPI and COPII proteins and clathrin, to the membrane during vesicle formation. + Golgi vesicle targeting + dictyosome vesicle targeting + vesicle targeting, to, from or within dictyosome + biological_process + GO:0048199 + vesicle targeting, to, from or within Golgi + + + + + The process in which vesicles are directed to specific destination membranes during transport to, from or within the Golgi apparatus; mediated by the addition of specific coat proteins, including COPI and COPII proteins and clathrin, to the membrane during vesicle formation. + GOC:jid + GOC:mah + ISBN:0716731363 + PMID:10219233 + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate, or destination of vesicle-mediated transport to, from or within the Golgi apparatus. + regulation of Golgi vesicle targeting + biological_process + GO:0048209 + regulation of vesicle targeting, to, from or within Golgi + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate, or destination of vesicle-mediated transport to, from or within the Golgi apparatus. + GOC:jid + GOC:mah + ISBN:0716731363 + PMID:10219233 + + + + + + + + + Generation of the male gamete; specialised haploid cells produced by meiosis and along with a female gamete takes part in sexual reproduction. + biological_process + GO:0048232 + male gamete generation + + + + + Generation of the male gamete; specialised haploid cells produced by meiosis and along with a female gamete takes part in sexual reproduction. + GOC:dph + GOC:jid + + + + + + + + + + + + + + + + + A process required for sperm to reach fertilization competence. Sperm undergo an incompletely understood series of morphological and molecular maturational processes, termed capacitation, involving, among other processes, protein tyrosine phosphorylation and increased intracellular calcium. + biological_process + sperm activation + GO:0048240 + Avian spermatozoa do not require a period of capacitation, since they are competent to fertilize the egg without a prolonged sojourn in the oviduct or in a capacitation medium in vitro. Therefore, sperm capacitation can only be applied to Aves to refer to gene products involved in processes that occur prior to sperm being deposited from the avian male. The term cannot apply to processes occurring in the avian female reproductive tract. + sperm capacitation + + + + + A process required for sperm to reach fertilization competence. Sperm undergo an incompletely understood series of morphological and molecular maturational processes, termed capacitation, involving, among other processes, protein tyrosine phosphorylation and increased intracellular calcium. + GOC:jid + ISBN:978-3-642-58301-8 + PMID:11820818 + + + + + sperm activation + PMID:23180860 + + + + + + + + + + + + + + + + + + + + The regulated release of norepinephrine by a cell. Norepinephrine is a catecholamine and it acts as a hormone and as a neurotransmitter of most of the sympathetic nervous system. + noradrenaline secretion + biological_process + GO:0048243 + norepinephrine secretion + + + + + The regulated release of norepinephrine by a cell. Norepinephrine is a catecholamine and it acts as a hormone and as a neurotransmitter of most of the sympathetic nervous system. + GOC:ef + GOC:jid + + + + + + + + + + + + + + + + + + + + Assembly of the extracellular matrix fibers that enables the matrix to recoil after transient stretching. + elastic fibre assembly + elastin fiber assembly + elastin fibre assembly + biological_process + GO:0048251 + elastic fiber assembly + + + + + Assembly of the extracellular matrix fibers that enables the matrix to recoil after transient stretching. + GOC:jid + PMID:10841810 + PMID:12615674 + + + + + elastin fiber assembly + GOC:BHF + + + + + elastin fibre assembly + GOC:BHF + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi. + biological_process + GO:0048280 + vesicle fusion with Golgi apparatus + + + + + The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi. + GOC:jid + + + + + + + + + + + + + + + + + + + + The creation of a single organelle from two or more organelles. + biological_process + GO:0048284 + + + organelle fusion + + + + + The creation of a single organelle from two or more organelles. + GOC:jid + + + + + + + + + + + + + + + + + + + + The creation of two or more organelles by division of one organelle. + biological_process + GO:0048285 + + + organelle fission + + + + + The creation of two or more organelles by division of one organelle. + GOC:jid + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the alveolus over time, from its formation to the mature structure. The alveolus is a sac for holding air in the lungs; formed by the terminal dilation of air passageways. + alveolarization + alveologenesis + biological_process + GO:0048286 + lung alveolus development + + + + + The process whose specific outcome is the progression of the alveolus over time, from its formation to the mature structure. The alveolus is a sac for holding air in the lungs; formed by the terminal dilation of air passageways. + GOC:mtg_lung + PMID:9751757 + + + + + alveolarization + PMID:17911382 + + + + + alveologenesis + GOC:17911382 + + + + + + + + + + + + + + + + + + + The joining of 2 or more lipid bilayer membranes that surround the nucleus during the creation of a single nucleus from multiple nuclei. + biological_process + nuclear membrane fusion during karyogamy + GO:0048288 + nuclear membrane fusion involved in karyogamy + + + + + The joining of 2 or more lipid bilayer membranes that surround the nucleus during the creation of a single nucleus from multiple nuclei. + GOC:jid + + + + + nuclear membrane fusion during karyogamy + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + Binding to a protein or protein complex in the presence of calcium. + molecular_function + GO:0048306 + calcium-dependent protein binding + + + + + Binding to a protein or protein complex in the presence of calcium. + GOC:jid + PMID:10485905 + + + + + + + + + The partitioning of organelles between daughter cells at cell division. + biological_process + GO:0048308 + + + organelle inheritance + + + + + The partitioning of organelles between daughter cells at cell division. + GOC:jid + + + + + + + + + + + + + + + + + + + + The partitioning of Golgi apparatus between daughter cells at cell division. + Golgi division + Golgi partitioning + biological_process + GO:0048313 + Golgi inheritance + + + + + The partitioning of Golgi apparatus between daughter cells at cell division. + GOC:jid + PMID:12851069 + + + + + Golgi division + GOC:ascb_2009 + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the axial mesoderm over time, from its formation to the mature structure. The axial mesoderm includes the prechordal mesoderm and the chordamesoderm. It gives rise to the prechordal plate and to the notochord. + biological_process + GO:0048318 + axial mesoderm development + + + + + The process whose specific outcome is the progression of the axial mesoderm over time, from its formation to the mature structure. The axial mesoderm includes the prechordal mesoderm and the chordamesoderm. It gives rise to the prechordal plate and to the notochord. + GOC:dgh + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the axial mesoderm are generated and organized. + biological_process + GO:0048319 + axial mesoderm morphogenesis + + + + + The process in which the anatomical structures of the axial mesoderm are generated and organized. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to the axial mesoderm. This process pertains to the initial formation of the structure from unspecified parts. + biological_process + GO:0048320 + axial mesoderm formation + + + + + The process that gives rise to the axial mesoderm. This process pertains to the initial formation of the structure from unspecified parts. + GOC:dgh + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the mesoderm are generated and organized. + biological_process + GO:0048332 + mesoderm morphogenesis + + + + + The process in which the anatomical structures of the mesoderm are generated and organized. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires the specialized features of a mesoderm cell. + mesoderm cell differentiation + biological_process + GO:0048333 + mesodermal cell differentiation + + + + + The process in which a relatively unspecialized cell acquires the specialized features of a mesoderm cell. + GOC:dgh + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the paraxial mesoderm over time, from its formation to the mature structure. The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube. + biological_process + GO:0048339 + paraxial mesoderm development + + + + + The process whose specific outcome is the progression of the paraxial mesoderm over time, from its formation to the mature structure. The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube. + GOC:dgh + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the paraxial mesoderm are generated and organized. + biological_process + GO:0048340 + paraxial mesoderm morphogenesis + + + + + The process in which the anatomical structures of the paraxial mesoderm are generated and organized. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to the paraxial mesoderm. This process pertains to the initial formation of the structure from unspecified parts. + biological_process + GO:0048341 + paraxial mesoderm formation + + + + + The process that gives rise to the paraxial mesoderm. This process pertains to the initial formation of the structure from unspecified parts. + GOC:dgh + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the lateral mesoderm over time, from its formation to the mature structure. + lateral plate mesoderm development + biological_process + GO:0048368 + lateral mesoderm development + + + + + The process whose specific outcome is the progression of the lateral mesoderm over time, from its formation to the mature structure. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the lateral mesoderm are generated and organized. + lateral plate mesoderm morphogenesis + biological_process + GO:0048369 + lateral mesoderm morphogenesis + + + + + The process in which the anatomical structures of the lateral mesoderm are generated and organized. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to the lateral mesoderm. This process pertains to the initial formation of the structure from unspecified parts. + lateral plate mesoderm biosynthesis + lateral plate mesoderm formation + biological_process + GO:0048370 + lateral mesoderm formation + + + + + The process that gives rise to the lateral mesoderm. This process pertains to the initial formation of the structure from unspecified parts. + GOC:jid + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the mesectoderm over time, from its formation to the mature structure. In animal embryos, mesectoderm development processes give rise to both mesoderm and ectoderm tissues. + biological_process + GO:0048383 + mesectoderm development + + + + + The process whose specific outcome is the progression of the mesectoderm over time, from its formation to the mature structure. In animal embryos, mesectoderm development processes give rise to both mesoderm and ectoderm tissues. + GOC:jid + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the intermediate mesoderm over time, from its formation to the mature structure. The intermediate mesoderm is located between the lateral mesoderm and the paraxial mesoderm. It develops into the kidney and gonads. + biological_process + GO:0048389 + intermediate mesoderm development + + + + + The process whose specific outcome is the progression of the intermediate mesoderm over time, from its formation to the mature structure. The intermediate mesoderm is located between the lateral mesoderm and the paraxial mesoderm. It develops into the kidney and gonads. + GOC:dgh + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the intermediate mesoderm are generated and organized. + biological_process + GO:0048390 + intermediate mesoderm morphogenesis + + + + + The process in which the anatomical structures of the intermediate mesoderm are generated and organized. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to the intermediate mesoderm. This process pertains to the initial formation of the structure from unspecified parts. + biological_process + GO:0048391 + intermediate mesoderm formation + + + + + The process that gives rise to the intermediate mesoderm. This process pertains to the initial formation of the structure from unspecified parts. + GOC:dgh + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. + biological_process + terminal differentiation + GO:0048468 + + cell development + + + + + The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. + GOC:go_curators + + + + + terminal differentiation + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for a cell to attain its fully functional state. + biological_process + functional differentiation + GO:0048469 + + cell maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for a cell to attain its fully functional state. + GOC:go_curators + + + + + functional differentiation + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster. + GO:0009993 + GO:0048157 + Wikipedia:Oogenesis + ovum development + biological_process + GO:0048477 + oogenesis + + + + + The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster. + GOC:kmv + GOC:mtg_sensu + GOC:pr + + + + + ovum development + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the autonomic nervous system over time, from its formation to the mature structure. The autonomic nervous system is composed of neurons that are not under conscious control, and is comprised of two antagonistic components, the sympathetic and parasympathetic nervous systems. The autonomic nervous system regulates key functions including the activity of the cardiac (heart) muscle, smooth muscles (e.g. of the gut), and glands. + biological_process + GO:0048483 + autonomic nervous system development + + + + + The process whose specific outcome is the progression of the autonomic nervous system over time, from its formation to the mature structure. The autonomic nervous system is composed of neurons that are not under conscious control, and is comprised of two antagonistic components, the sympathetic and parasympathetic nervous systems. The autonomic nervous system regulates key functions including the activity of the cardiac (heart) muscle, smooth muscles (e.g. of the gut), and glands. + FMA:9905 + GOC:jid + GOC:sr + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the enteric nervous system over time, from its formation to the mature structure. The enteric nervous system is composed of two ganglionated neural plexuses in the gut wall which form one of the three major divisions of the autonomic nervous system. The enteric nervous system innervates the gastrointestinal tract, the pancreas, and the gall bladder. It contains sensory neurons, interneurons, and motor neurons. Thus the circuitry can autonomously sense the tension and the chemical environment in the gut and regulate blood vessel tone, motility, secretions, and fluid transport. The system is itself governed by the central nervous system and receives both parasympathetic and sympathetic innervation. + biological_process + GO:0048484 + enteric nervous system development + + + + + The process whose specific outcome is the progression of the enteric nervous system over time, from its formation to the mature structure. The enteric nervous system is composed of two ganglionated neural plexuses in the gut wall which form one of the three major divisions of the autonomic nervous system. The enteric nervous system innervates the gastrointestinal tract, the pancreas, and the gall bladder. It contains sensory neurons, interneurons, and motor neurons. Thus the circuitry can autonomously sense the tension and the chemical environment in the gut and regulate blood vessel tone, motility, secretions, and fluid transport. The system is itself governed by the central nervous system and receives both parasympathetic and sympathetic innervation. + FMA:66070 + GOC:jid + GOC:sr + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the sympathetic nervous system over time, from its formation to the mature structure. The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter. + biological_process + GO:0048485 + sympathetic nervous system development + + + + + The process whose specific outcome is the progression of the sympathetic nervous system over time, from its formation to the mature structure. The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter. + FMA:9906 + GOC:jid + GOC:sr + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the parasympathetic nervous system over time, from its formation to the mature structure. The parasympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia. + biological_process + GO:0048486 + parasympathetic nervous system development + + + + + The process whose specific outcome is the progression of the parasympathetic nervous system over time, from its formation to the mature structure. The parasympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia. + FMA:9907 + GOC:jid + GOC:sr + + + + + + + + + + + + + + + + + + + + + Any process pertinent to the generation and maintenance of rhythms in the physiology of an organism. + biological_process + rhythm + GO:0048511 + + rhythmic process + + + + + Any process pertinent to the generation and maintenance of rhythms in the physiology of an organism. + GOC:jid + + + + + + + + + + The specific behavior of an organism that recurs with a regularity of approximately 24 hours. + circadian rhythm behavior + biological_process + GO:0048512 + circadian behavior + + + + + The specific behavior of an organism that recurs with a regularity of approximately 24 hours. + GOC:bf + GOC:go_curators + GOC:pr + + + + + + + + + + + + + + + + + + + + Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. + Wikipedia:Organogenesis + development of an organ + organogenesis + biological_process + GO:0048513 + animal organ development + + + + + Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. + GOC:dph + GOC:jid + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of blood vessels are generated and organized. The blood vessel is the vasculature carrying blood. + biological_process + GO:0048514 + blood vessel morphogenesis + + + + + The process in which the anatomical structures of blood vessels are generated and organized. The blood vessel is the vasculature carrying blood. + GOC:jid + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a spermatid over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. + spermatid cell differentiation + biological_process + GO:0048515 + spermatid differentiation + + + + + The process whose specific outcome is the progression of a spermatid over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. + GOC:dph + GOC:jid + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. + GO:0043119 + positive regulation of physiological process + up regulation of biological process + up-regulation of biological process + upregulation of biological process + activation of biological process + stimulation of biological process + biological_process + GO:0048518 + + positive regulation of biological process + + + + + Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. + GOC:jid + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. + GO:0043118 + down regulation of biological process + down-regulation of biological process + downregulation of biological process + negative regulation of physiological process + inhibition of biological process + biological_process + GO:0048519 + + negative regulation of biological process + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. + GOC:jid + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli. + up regulation of behavior + up-regulation of behavior + upregulation of behavior + activation of behavior + stimulation of behavior + biological_process + GO:0048520 + positive regulation of behavior + + + + + Any process that activates or increases the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli. + GOC:jid + GOC:pr + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli. + down regulation of behavior + down-regulation of behavior + downregulation of behavior + inhibition of behavior + biological_process + GO:0048521 + negative regulation of behavior + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli. + GOC:jid + GOC:pr + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. + GO:0051242 + positive regulation of cellular physiological process + up regulation of cellular process + up-regulation of cellular process + upregulation of cellular process + activation of cellular process + stimulation of cellular process + biological_process + GO:0048522 + + positive regulation of cellular process + + + + + Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. + GOC:jid + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. + GO:0051243 + down regulation of cellular process + down-regulation of cellular process + downregulation of cellular process + negative regulation of cellular physiological process + inhibition of cellular process + biological_process + GO:0048523 + + negative regulation of cellular process + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. + GOC:jid + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of any organ involved in hematopoiesis (also known as hemopoiesis) or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation. + haematopoietic or lymphoid organ development + haemopoietic or lymphoid organ development + hemopoietic or lymphoid organ development + biological_process + GO:0048534 + hematopoietic or lymphoid organ development + + + + + The process whose specific outcome is the progression of any organ involved in hematopoiesis (also known as hemopoiesis) or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation. + GOC:add + GOC:rl + ISBN:0781735149 + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of lymph nodes over time, from their formation to the mature structure. A lymph node is a round, oval, or bean shaped structure localized in clusters along the lymphatic vessels, with a distinct internal structure including specialized vasculature and B- and T-zones for the activation of lymphocytes. + lymph gland development + biological_process + GO:0048535 + lymph node development + + + + + The process whose specific outcome is the progression of lymph nodes over time, from their formation to the mature structure. A lymph node is a round, oval, or bean shaped structure localized in clusters along the lymphatic vessels, with a distinct internal structure including specialized vasculature and B- and T-zones for the activation of lymphocytes. + GOC:add + ISBN:068340007X + ISBN:0781735149 + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the spleen over time, from its formation to the mature structure. The spleen is a large vascular lymphatic organ composed of white and red pulp, involved both in hemopoietic and immune system functions. + biological_process + GO:0048536 + spleen development + + + + + The process whose specific outcome is the progression of the spleen over time, from its formation to the mature structure. The spleen is a large vascular lymphatic organ composed of white and red pulp, involved both in hemopoietic and immune system functions. + GOC:add + ISBN:0781735149 + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of mucosal-associated lymphoid tissue over time, from its formation to the mature structure. Mucosal-associated lymphoid tissue is typically found as nodules associated with mucosal epithelia with distinct internal structures including B- and T-zones for the activation of lymphocytes. + https://github.com/geneontology/go-ontology/issues/19918 + mucosal-associated lymphoid tissue development + BALT development + GALT development + NALT development + bronchial-associated lymphoid tissue development + gut-associated lymphoid tissue development + nasopharyngeal-associated lymphoid tissue development + biological_process + GO:0048537 + mucosa-associated lymphoid tissue development + + + + + The process whose specific outcome is the progression of mucosal-associated lymphoid tissue over time, from its formation to the mature structure. Mucosal-associated lymphoid tissue is typically found as nodules associated with mucosal epithelia with distinct internal structures including B- and T-zones for the activation of lymphocytes. + GOC:add + ISBN:0781735149 + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the thymus over time, from its formation to the mature structure. The thymus is a symmetric bi-lobed organ involved primarily in the differentiation of immature to mature T cells, with unique vascular, nervous, epithelial, and lymphoid cell components. + biological_process + GO:0048538 + Note that this term is reserved for annotation of gene products involved in the formation of the thymus itself, not for gene products involved in T cell differentiation in the thymus or elsewhere. + thymus development + + + + + The process whose specific outcome is the progression of the thymus over time, from its formation to the mature structure. The thymus is a symmetric bi-lobed organ involved primarily in the differentiation of immature to mature T cells, with unique vascular, nervous, epithelial, and lymphoid cell components. + GOC:add + ISBN:0781735149 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the bone marrow over time, from its formation to the mature structure. + biological_process + GO:0048539 + bone marrow development + + + + + The process whose specific outcome is the progression of the bone marrow over time, from its formation to the mature structure. + GOC:add + ISBN:0781735149 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the bursa of Fabricius over time, from its formation to the mature structure. The bursa of Fabricius is an organ found in birds involved in B cell differentiation. + biological_process + GO:0048540 + bursa of Fabricius development + + + + + The process whose specific outcome is the progression of the bursa of Fabricius over time, from its formation to the mature structure. The bursa of Fabricius is an organ found in birds involved in B cell differentiation. + GOC:add + ISBN:0781735149 + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of Peyer's patches over time, from their formation to the mature structure. Peyer's patches are typically found as nodules associated with gut epithelium with distinct internal structures including B- and T-zones for the activation of lymphocytes. + biological_process + GALT development + gut-associated lymphoid tissue development + GO:0048541 + Peyer's patch development + + + + + The process whose specific outcome is the progression of Peyer's patches over time, from their formation to the mature structure. Peyer's patches are typically found as nodules associated with gut epithelium with distinct internal structures including B- and T-zones for the activation of lymphocytes. + GOC:add + ISBN:0781735149 + + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus. + response to steroid hormone stimulus + biological_process + GO:0048545 + response to steroid hormone + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus. + GOC:go_curators + + + + + response to steroid hormone stimulus + GOC:dos + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the digestive tract are generated and organized. The digestive tract is the anatomical structure through which food passes and is processed. + GO:0048547 + gut morphogenesis + alimentary canal morphogenesis + digestive tube morphogenesis + gastrointestinal tract morphogenesis + intestinal morphogenesis + biological_process + GO:0048546 + digestive tract morphogenesis + + + + + The process in which the anatomical structures of the digestive tract are generated and organized. The digestive tract is the anatomical structure through which food passes and is processed. + GOC:dph + GOC:go_curators + PMID:12618131 + + + + + gut morphogenesis + GOC:dph + + + + + + + + + + + + + + + + Morphogenesis, during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. + biological_process + GO:0048562 + embryonic organ morphogenesis + + + + + Morphogenesis, during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. + GOC:jid + + + + + + + + + + + + + + + + Morphogenesis, during the post-embryonic phase, of an animal tissue or tissues that work together to perform a specific function or functions. Morphogenesis pertains to process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. + biological_process + GO:0048563 + post-embryonic animal organ morphogenesis + + + + + Morphogenesis, during the post-embryonic phase, of an animal tissue or tissues that work together to perform a specific function or functions. Morphogenesis pertains to process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. + GOC:jid + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the digestive tract over time, from its formation to the mature structure. The digestive tract is the anatomical structure through which food passes and is processed. + gut development + intestinal development + intestine development + biological_process + GO:0048565 + digestive tract development + + + + + The process whose specific outcome is the progression of the digestive tract over time, from its formation to the mature structure. The digestive tract is the anatomical structure through which food passes and is processed. + GOC:go_curators + + + + + gut development + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Development, taking place during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. + embryonic organogenesis + biological_process + GO:0048568 + embryonic organ development + + + + + Development, taking place during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. + GOC:jid + + + + + + + + + + Development, taking place during the post-embryonic phase of an animal tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. + post-embryonic animal organogenesis + biological_process + GO:0048569 + post-embryonic animal organ development + + + + + Development, taking place during the post-embryonic phase of an animal tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. + GOC:jid + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the notochord are generated and organized. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column. + biological_process + GO:0048570 + notochord morphogenesis + + + + + The process in which the anatomical structures of the notochord are generated and organized. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column. + GOC:jid + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. + biological_process + GO:0048580 + regulation of post-embryonic development + + + + + Any process that modulates the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. + GOC:jid + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. + down regulation of post-embryonic development + down-regulation of post-embryonic development + downregulation of post-embryonic development + inhibition of post-embryonic development + biological_process + GO:0048581 + negative regulation of post-embryonic development + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. + GOC:jid + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. + up regulation of post-embryonic development + up-regulation of post-embryonic development + upregulation of post-embryonic development + activation of post-embryonic development + stimulation of post-embryonic development + biological_process + GO:0048582 + positive regulation of post-embryonic development + + + + + Any process that activates or increases the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. + GOC:jid + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. + biological_process + GO:0048583 + + Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. + regulation of response to stimulus + + + + + Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. + GOC:jid + + + + + + + + + + + + + + + + + + + + + Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. + up regulation of response to stimulus + up-regulation of response to stimulus + upregulation of response to stimulus + activation of response to stimulus + stimulation of response to stimulus + biological_process + GO:0048584 + + Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. + positive regulation of response to stimulus + + + + + Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. + GOC:jid + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. + down regulation of response to stimulus + down-regulation of response to stimulus + downregulation of response to stimulus + inhibition of response to stimulus + biological_process + GO:0048585 + + Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. + negative regulation of response to stimulus + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. + GOC:jid + + + + + + + + + + + + + + + + The growth of a cell, where growth contributes to the progression of the cell over time from one condition to another. + developmental growth of a unicellular organism + biological_process + GO:0048588 + developmental cell growth + + + + + The growth of a cell, where growth contributes to the progression of the cell over time from one condition to another. + GOC:go_curators + GOC:isa_complete + + + + + + + + + + + + + + + + + + + The increase in size or mass of an entire organism, a part of an organism or a cell, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another. + biological_process + GO:0048589 + developmental growth + + + + + The increase in size or mass of an entire organism, a part of an organism or a cell, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the eye are generated and organized. + GO:0048748 + biological_process + GO:0048592 + eye morphogenesis + + + + + The process in which the anatomical structures of the eye are generated and organized. + GOC:jid + GOC:mtg_sensu + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the eye are generated and organized. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field. + GO:0048594 + GO:0048595 + camera-style eye morphogenesis + biological_process + GO:0048593 + camera-type eye morphogenesis + + + + + The process in which the anatomical structures of the eye are generated and organized. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field. + GOC:jid + GOC:mtg_sensu + + + + + camera-style eye morphogenesis + GOC:dph + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the eye are generated and organized during embryonic development. + embryonic eye morphogenesis + biological_process + GO:0048596 + embryonic camera-type eye morphogenesis + + + + + The process in which the anatomical structures of the eye are generated and organized during embryonic development. + GOC:jid + GOC:mtg_sensu + + + + + + + + + + + + + + + + The process in which anatomical structures are generated and organized during the embryonic phase. The embryonic phase begins with zygote formation. The end of the embryonic phase is organism-specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants. + GO:0048828 + embryonic anatomical structure morphogenesis + biological_process + GO:0048598 + embryonic morphogenesis + + + + + The process in which anatomical structures are generated and organized during the embryonic phase. The embryonic phase begins with zygote formation. The end of the embryonic phase is organism-specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants. + GOC:jid + GOC:mtg_sensu + + + + + embryonic anatomical structure morphogenesis + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. + biological_process + GO:0048599 + oocyte development + + + + + The process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the structures of an oocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of an oocyte. + oocyte morphogenesis during differentiation + biological_process + GO:0048601 + oocyte morphogenesis + + + + + The process in which the structures of an oocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of an oocyte. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + + + + + + The reproductive developmental process whose specific outcome is the progression of somatic structures that will be used in the process of creating new individuals from one or more parents, from their formation to the mature structures. + biological_process + GO:0048608 + reproductive structure development + + + + + The reproductive developmental process whose specific outcome is the progression of somatic structures that will be used in the process of creating new individuals from one or more parents, from their formation to the mature structures. + GOC:dph + GOC:isa_complete + GOC:jid + + + + + + + + + + + + + + + The process, occurring above the cellular level, that is pertinent to the reproductive function of a multicellular organism. This includes the integrated processes at the level of tissues and organs. + organismal reproductive process + reproductive process in a multicellular organism + biological_process + GO:0048609 + multicellular organismal reproductive process + + + + + The process, occurring above the cellular level, that is pertinent to the reproductive function of a multicellular organism. This includes the integrated processes at the level of tissues and organs. + GOC:dph + GOC:jid + GOC:tb + + + + + + + + + + + + + + + The process in which the anatomical structures of the hindgut are generated and organized, during the embryonic phase. + biological_process + GO:0048619 + embryonic hindgut morphogenesis + + + + + The process in which the anatomical structures of the hindgut are generated and organized, during the embryonic phase. + GOC:jid + GOC:rc + + + + + + + + + + + + + + + + + + + + + + + + + + The increase in size or mass of a skeletal muscle. This may be due to a change in the fiber number or size. + biological_process + GO:0048630 + skeletal muscle tissue growth + + + + + The increase in size or mass of a skeletal muscle. This may be due to a change in the fiber number or size. + GOC:lm + PMID:15726494 + PMID:15907921 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of skeletal muscle growth. + biological_process + GO:0048631 + regulation of skeletal muscle tissue growth + + + + + Any process that modulates the frequency, rate or extent of skeletal muscle growth. + GOC:lm + PMID:15726494 + PMID:15907921 + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle growth. + down regulation of skeletal muscle growth + down-regulation of skeletal muscle growth + downregulation of skeletal muscle growth + inhibition of skeletal muscle growth + biological_process + GO:0048632 + negative regulation of skeletal muscle tissue growth + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle growth. + GOC:lm + PMID:15726494 + PMID:15907921 + + + + + + + + + + + + + + + + + + + + + + + + + Any process that activates, maintains or increases the rate of skeletal muscle growth. + up regulation of skeletal muscle growth + up-regulation of skeletal muscle growth + upregulation of skeletal muscle growth + activation of skeletal muscle growth + stimulation of skeletal muscle growth + biological_process + GO:0048633 + positive regulation of skeletal muscle tissue growth + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that activates, maintains or increases the rate of skeletal muscle growth. + GOC:lm + PMID:15726494 + PMID:15907921 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of muscle development. + biological_process + GO:0048634 + regulation of muscle organ development + + + + + Any process that modulates the frequency, rate or extent of muscle development. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of muscle development. + down regulation of muscle development + down-regulation of muscle development + downregulation of muscle development + inhibition of muscle development + biological_process + GO:0048635 + negative regulation of muscle organ development + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of muscle development. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + + + + Any process that activates, maintains or increases the rate of muscle development. + up regulation of muscle development + up-regulation of muscle development + upregulation of muscle development + activation of muscle development + stimulation of muscle development + biological_process + GO:0048636 + positive regulation of muscle organ development + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that activates, maintains or increases the rate of muscle development. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of developmental growth. + biological_process + GO:0048638 + regulation of developmental growth + + + + + Any process that modulates the frequency, rate or extent of developmental growth. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + Any process that activates, maintains or increases the rate of developmental growth. + up regulation of developmental growth + up-regulation of developmental growth + upregulation of developmental growth + activation of developmental growth + stimulation of developmental growth + biological_process + GO:0048639 + positive regulation of developmental growth + + + + + Any process that activates, maintains or increases the rate of developmental growth. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of developmental growth. + down regulation of developmental growth + down-regulation of developmental growth + downregulation of developmental growth + inhibition of developmental growth + biological_process + GO:0048640 + negative regulation of developmental growth + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of developmental growth. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of skeletal muscle tissue development. + biological_process + GO:0048641 + regulation of skeletal muscle tissue development + + + + + Any process that modulates the frequency, rate or extent of skeletal muscle tissue development. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle tissue development. + down regulation of skeletal muscle development + down-regulation of skeletal muscle development + downregulation of skeletal muscle development + inhibition of skeletal muscle development + biological_process + GO:0048642 + negative regulation of skeletal muscle tissue development + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle tissue development. + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that activates, maintains or increases the rate of skeletal muscle tissue development. + up regulation of skeletal muscle development + up-regulation of skeletal muscle development + upregulation of skeletal muscle development + activation of skeletal muscle development + stimulation of skeletal muscle development + biological_process + GO:0048643 + positive regulation of skeletal muscle tissue development + + + + + Any process that activates, maintains or increases the rate of skeletal muscle tissue development. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of muscle are generated and organized. + biological_process + GO:0048644 + muscle organ morphogenesis + + + + + The process in which the anatomical structures of muscle are generated and organized. + GOC:jid + + + + + + + + + + + + + + + + + + + + + + + + + + + The process pertaining to the initial formation of an animal organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment. Organs are a natural part or structure in an animal or a plant, capable of performing some special action (termed its function), which is essential to the life or well-being of the whole. The heart and lungs are organs of animals, and the petal and leaf are organs of plants. In animals the organs are generally made up of several tissues, one of which usually predominates, and determines the principal function of the organ. + animal organ primordium initiation + initiation of an animal organ primordium + biological_process + GO:0048645 + animal organ formation + + + + + The process pertaining to the initial formation of an animal organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment. Organs are a natural part or structure in an animal or a plant, capable of performing some special action (termed its function), which is essential to the life or well-being of the whole. The heart and lungs are organs of animals, and the petal and leaf are organs of plants. In animals the organs are generally made up of several tissues, one of which usually predominates, and determines the principal function of the organ. + GOC:dph + GOC:jid + + + + + + + + + + + + + + + The developmental process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. + formation of an anatomical structure involved in morphogenesis + biological_process + GO:0048646 + + Note that, for example, the formation of a pseudopod in an amoeba would not be considered formation involved in morphogenesis because it would not be thought of as the formation of an anatomical structure that was part of the shaping of the amoeba during its development. The formation of an axon from a neuron would be considered the formation of an anatomical structure involved in morphogenesis because it contributes to the creation of the form of the neuron in a developmental sense. + anatomical structure formation involved in morphogenesis + + + + + The developmental process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. + GOC:dph + GOC:jid + GOC:tb + + + + + formation of an anatomical structure involved in morphogenesis + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + The multiplication or reproduction of smooth muscle cells, resulting in the expansion of a cell population. + SMC proliferation + biological_process + GO:0048659 + smooth muscle cell proliferation + + + + + The multiplication or reproduction of smooth muscle cells, resulting in the expansion of a cell population. + CL:0000192 + GOC:ebc + PMID:1840698 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of smooth muscle cell proliferation. + regulation of SMC proliferation + biological_process + GO:0048660 + regulation of smooth muscle cell proliferation + + + + + Any process that modulates the frequency, rate or extent of smooth muscle cell proliferation. + CL:0000192 + GOC:ebc + + + + + + + + + + + + + + + + + + + Any process that activates or increases the rate or extent of smooth muscle cell proliferation. + positive regulation of SMC proliferation + up regulation of smooth muscle cell proliferation + up-regulation of smooth muscle cell proliferation + upregulation of smooth muscle cell proliferation + activation of smooth muscle cell proliferation + stimulation of smooth muscle cell proliferation + biological_process + GO:0048661 + positive regulation of smooth muscle cell proliferation + + + + + Any process that activates or increases the rate or extent of smooth muscle cell proliferation. + CL:0000192 + GOC:ebc + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the rate or extent of smooth muscle cell proliferation. + down regulation of smooth muscle cell proliferation + down-regulation of smooth muscle cell proliferation + downregulation of smooth muscle cell proliferation + negative regulation of SMC proliferation + inhibition of smooth muscle cell proliferation + biological_process + GO:0048662 + negative regulation of smooth muscle cell proliferation + + + + + Any process that stops, prevents or reduces the rate or extent of smooth muscle cell proliferation. + CL:0000192 + GOC:ebc + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. + biological_process + GO:0048666 + neuron development + + + + + The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the structures of a neuron are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a neuron. + neuron morphogenesis involved in differentiation + biological_process + GO:0048667 + cell morphogenesis involved in neuron differentiation + + + + + The process in which the structures of a neuron are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a neuron. + GOC:dph + GOC:tb + + + + + neuron morphogenesis involved in differentiation + GOC:dph + GOC:tb + + + + + + + + + The process in which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons. + neuron generation + biological_process + GO:0048699 + generation of neurons + + + + + The process in which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons. + GOC:nln + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the skeleton are generated and organized. + skeletal morphogenesis + biological_process + GO:0048705 + skeletal system morphogenesis + + + + + The process in which the anatomical structures of the skeleton are generated and organized. + GOC:dph + GOC:dsf + GOC:jid + GOC:tb + + + + + skeletal morphogenesis + GOC:dph + GOC:tb + + + + + + + + + + + + + + + The process, occurring during instar larval or pupal development, by which anatomical structures are generated and organized. + biological_process + GO:0048707 + instar larval or pupal morphogenesis + + + + + The process, occurring during instar larval or pupal development, by which anatomical structures are generated and organized. + GOC:mtg_sensu + GOC:rc + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function. + biological_process + GO:0048708 + astrocyte differentiation + + + + + The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function. + GOC:vp + PMID:15139015 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system. + biological_process + GO:0048709 + oligodendrocyte differentiation + + + + + The process in which a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system. + GOC:vp + PMID:15139015 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of astrocyte differentiation. + biological_process + GO:0048710 + regulation of astrocyte differentiation + + + + + Any process that modulates the frequency, rate or extent of astrocyte differentiation. + GOC:vp + PMID:15139015 + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of astrocyte differentiation. + up regulation of astrocyte differentiation + up-regulation of astrocyte differentiation + upregulation of astrocyte differentiation + activation of astrocyte differentiation + stimulation of astrocyte differentiation + biological_process + GO:0048711 + positive regulation of astrocyte differentiation + + + + + Any process that activates or increases the frequency, rate or extent of astrocyte differentiation. + GOC:vp + PMID:15139015 + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of astrocyte differentiation. + down regulation of astrocyte differentiation + down-regulation of astrocyte differentiation + downregulation of astrocyte differentiation + inhibition of astrocyte differentiation + biological_process + GO:0048712 + negative regulation of astrocyte differentiation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of astrocyte differentiation. + GOC:vp + PMID:15139015 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of oligodendrocyte differentiation. + biological_process + GO:0048713 + regulation of oligodendrocyte differentiation + + + + + Any process that modulates the frequency, rate or extent of oligodendrocyte differentiation. + GOC:vp + PMID:15139015 + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of oligodendrocyte differentiation. + up regulation of oligodendrocyte differentiation + up-regulation of oligodendrocyte differentiation + upregulation of oligodendrocyte differentiation + activation of oligodendrocyte differentiation + stimulation of oligodendrocyte differentiation + biological_process + GO:0048714 + positive regulation of oligodendrocyte differentiation + + + + + Any process that activates or increases the frequency, rate or extent of oligodendrocyte differentiation. + GOC:vp + PMID:15139015 + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of oligodendrocyte differentiation. + down regulation of oligodendrocyte differentiation + down-regulation of oligodendrocyte differentiation + downregulation of oligodendrocyte differentiation + inhibition of oligodendrocyte differentiation + biological_process + GO:0048715 + negative regulation of oligodendrocyte differentiation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of oligodendrocyte differentiation. + GOC:vp + PMID:15139015 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of a tissue are generated and organized. + biological_process + GO:0048729 + tissue morphogenesis + + + + + The process in which the anatomical structures of a tissue are generated and organized. + GOC:dph + GOC:jid + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the epidermis are generated and organized. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species. + biological_process + hypodermis morphogenesis + GO:0048730 + epidermis morphogenesis + + + + + The process in which the anatomical structures of the epidermis are generated and organized. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species. + GOC:jid + UBERON:0001003 + + + + + hypodermis morphogenesis + GOC:kmv + GOC:rk + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process. + biological_process + GO:0048731 + + system development + + + + + The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process. + GOC:dph + GOC:jid + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a gland over time, from its formation to the mature structure. A gland is an organ specialised for secretion. + biological_process + GO:0048732 + gland development + + + + + The process whose specific outcome is the progression of a gland over time, from its formation to the mature structure. A gland is an organ specialised for secretion. + GOC:jid + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the sebaceous gland over time, from its formation to the mature structure. + biological_process + GO:0048733 + sebaceous gland development + + + + + The process whose specific outcome is the progression of the sebaceous gland over time, from its formation to the mature structure. + GOC:jid + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of a haltere are generated and organized. + biological_process + GO:0048735 + haltere morphogenesis + + + + + The process in which the anatomical structures of a haltere are generated and organized. + GOC:jid + GOC:rc + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of an appendage over time, from its formation to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch. + biological_process + GO:0048736 + appendage development + + + + + The process whose specific outcome is the progression of an appendage over time, from its formation to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch. + GOC:jid + GOC:rc + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of an appendage over time, from its formation in the imaginal disc to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism. + biological_process + GO:0048737 + imaginal disc-derived appendage development + + + + + The process whose specific outcome is the progression of an appendage over time, from its formation in the imaginal disc to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism. + GOC:jid + GOC:mtg_sensu + GOC:rc + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of cardiac muscle over time, from its formation to the mature structure. + heart muscle development + biological_process + GO:0048738 + cardiac muscle tissue development + + + + + The process whose specific outcome is the progression of cardiac muscle over time, from its formation to the mature structure. + GOC:dph + GOC:jid + GOC:lm + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the skeletal muscle fiber over time, from its formation to the mature structure. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast. + skeletal muscle fibre development + skeletal myofiber development + skeletal myofibre development + biological_process + GO:0048741 + skeletal muscle fiber development + + + + + The process whose specific outcome is the progression of the skeletal muscle fiber over time, from its formation to the mature structure. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast. + GOC:dph + GOC:ef + GOC:jid + GOC:lm + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast. + regulation of skeletal muscle fibre development + regulation of skeletal myofiber development + regulation of skeletal myofibre development + biological_process + GO:0048742 + regulation of skeletal muscle fiber development + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast. + GOC:dph + GOC:jid + GOC:mtg_muscle + GOC:sm + + + + + + + + + + + + + + + + + + + + + Any process that activates, maintains or increases the rate of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast. + positive regulation of skeletal muscle fibre development + positive regulation of skeletal myofiber development + positive regulation of skeletal myofibre development + up regulation of skeletal muscle fiber development + up-regulation of skeletal muscle fiber development + upregulation of skeletal muscle fiber development + activation of skeletal muscle fiber development + stimulation of skeletal muscle fiber development + biological_process + GO:0048743 + positive regulation of skeletal muscle fiber development + + + + + Any process that activates, maintains or increases the rate of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast. + GOC:dph + GOC:jid + GOC:lm + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast. + down regulation of skeletal muscle fiber development + down-regulation of skeletal muscle fiber development + downregulation of skeletal muscle fiber development + negative regulation of skeletal muscle fibre development + negative regulation of skeletal myofiber development + negative regulation of skeletal myofibre development + inhibition of skeletal muscle fiber development + biological_process + GO:0048744 + negative regulation of skeletal muscle fiber development + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast. + GOC:dph + GOC:jid + GOC:lm + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of smooth muscle over time, from its formation to the mature structure. + biological_process + GO:0048745 + smooth muscle tissue development + + + + + The process whose specific outcome is the progression of smooth muscle over time, from its formation to the mature structure. + GOC:dph + GOC:jid + GOC:lm + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the compound eye over time, from its formation to the mature structure. The compound eye is an organ of sight that contains multiple repeating units, often arranged hexagonally. Each unit has its own lens and photoreceptor cell(s) and can generate either a single pixelated image or multiple images, per eye. + GO:0007456 + insect-type retina development + biological_process + GO:0048749 + compound eye development + + + + + The process whose specific outcome is the progression of the compound eye over time, from its formation to the mature structure. The compound eye is an organ of sight that contains multiple repeating units, often arranged hexagonally. Each unit has its own lens and photoreceptor cell(s) and can generate either a single pixelated image or multiple images, per eye. + GOC:jid + GOC:mtg_sensu + Wikipedia:Eye + + + + + insect-type retina development + PMID:11735386 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the compound eye corneal lens are generated and organized. + biological_process + GO:0048750 + compound eye corneal lens morphogenesis + + + + + The process in which the anatomical structures of the compound eye corneal lens are generated and organized. + GOC:jid + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the semicircular canals are generated and organized. + embryonic semicircular canal morphogenesis + biological_process + GO:0048752 + semicircular canal morphogenesis + + + + + The process in which the anatomical structures of the semicircular canals are generated and organized. + GOC:dgh + GOC:dph + GOC:jid + + + + + + + + + + + + + + + + + + + + + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pigment granule. + pigment granule organisation + biological_process + pigment granule organization and biogenesis + GO:0048753 + + pigment granule organization + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pigment granule. + GOC:rc + + + + + pigment granule organization and biogenesis + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of branches in an epithelial tube are generated and organized. A tube is a long hollow cylinder. + biological_process + tubulogenesis + GO:0048754 + branching morphogenesis of an epithelial tube + + + + + The process in which the anatomical structures of branches in an epithelial tube are generated and organized. A tube is a long hollow cylinder. + GOC:dgh + GOC:dph + GOC:jid + + + + + tubulogenesis + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of branches in a nerve are generated and organized. This term refers to an anatomical structure (nerve) not a cell (neuron). + biological_process + GO:0048755 + branching morphogenesis of a nerve + + + + + The process in which the anatomical structures of branches in a nerve are generated and organized. This term refers to an anatomical structure (nerve) not a cell (neuron). + GOC:dgh + GOC:dph + GOC:jid + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types. + biological_process + GO:0048762 + mesenchymal cell differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types. + GOC:dph + GOC:jid + + + + + + + + + A small, subcellular membrane-bounded vesicle containing pigment and/or pigment precursor molecules. Pigment granule biogenesis is poorly understood, as pigment granules are derived from multiple sources including the endoplasmic reticulum, coated vesicles, lysosomes, and endosomes. + cellular_component + GO:0048770 + pigment granule + + + + + A small, subcellular membrane-bounded vesicle containing pigment and/or pigment precursor molecules. Pigment granule biogenesis is poorly understood, as pigment granules are derived from multiple sources including the endoplasmic reticulum, coated vesicles, lysosomes, and endosomes. + GOC:jid + GOC:mh + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the hatching gland over time, from its formation to the mature structure. The cells of the hatching gland contain enzymes responsible for solubilization of the egg chorion, facilitating the hatching process. + biological_process + GO:0048785 + hatching gland development + + + + + The process whose specific outcome is the progression of the hatching gland over time, from its formation to the mature structure. The cells of the hatching gland contain enzymes responsible for solubilization of the egg chorion, facilitating the hatching process. + GOC:bf + GOC:dh + GOC:jid + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the pronephros over time, from its formation to the mature structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life. + pronephric kidney development + biological_process + GO:0048793 + pronephros development + + + + + The process whose specific outcome is the progression of the pronephros over time, from its formation to the mature structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life. + GOC:bf + GOC:mtg_kidney_jan10 + PMID:10535314 + PMID:15968585 + PMID:18322540 + XAO:00002000 + ZFA:0000151 + + + + + pronephric kidney development + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the swim bladder over time, from its formation to the mature structure. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ. + gas bladder development + biological_process + GO:0048794 + swim bladder development + + + + + The process whose specific outcome is the progression of the swim bladder over time, from its formation to the mature structure. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ. + GOC:mh + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of the swim bladder is generated and organized. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ. + gas bladder morphogenesis + biological_process + GO:0048795 + swim bladder morphogenesis + + + + + The process in which the anatomical structure of the swim bladder is generated and organized. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ. + GOC:mh + + + + + + + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for a swim bladder to attain its fully functional state. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ. + gas bladder maturation + biological_process + GO:0048796 + swim bladder maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for a swim bladder to attain its fully functional state. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ. + GOC:devbiol + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to the swim bladder. This process pertains to the initial formation of a structure from unspecified parts. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ. + gas bladder biosynthesis + gas bladder formation + biological_process + GO:0048797 + swim bladder formation + + + + + The process that gives rise to the swim bladder. This process pertains to the initial formation of a structure from unspecified parts. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ. + GOC:mh + + + + + + + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for an animal organ to attain its fully functional state. An organ is a tissue or set of tissues that work together to perform a specific function or functions. + biological_process + GO:0048799 + animal organ maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for an animal organ to attain its fully functional state. An organ is a tissue or set of tissues that work together to perform a specific function or functions. + GOC:curators + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the antenna are generated and organized. + biological_process + GO:0048800 + antennal morphogenesis + + + + + The process in which the anatomical structures of the antenna are generated and organized. + GOC:jid + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the genitalia over time, from its formation to the mature structure. + genital development + biological_process + GO:0048806 + genitalia development + + + + + The process whose specific outcome is the progression of the genitalia over time, from its formation to the mature structure. + GOC:jid + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of male genitalia are generated and organized. + biological_process + male genital morphogenesis + GO:0048808 + male genitalia morphogenesis + + + + + The process in which the anatomical structures of male genitalia are generated and organized. + GOC:ems + ISBN:0140512888 + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites. + neurite biosynthesis + neurite formation + neurite growth + biological_process + neurite morphogenesis + GO:0048812 + neuron projection morphogenesis + + + + + The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites. + GOC:mah + + + + + neurite morphogenesis + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of a dendrite are generated and organized. + biological_process + GO:0048813 + dendrite morphogenesis + + + + + The process in which the anatomical structures of a dendrite are generated and organized. + GOC:aruk + GOC:bc + GOC:jl + ISBN:0198506732 + PMID:22683681 + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of dendrite morphogenesis. + biological_process + GO:0048814 + regulation of dendrite morphogenesis + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate or extent of dendrite morphogenesis. + GOC:ai + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of hermaphrodite genitalia are generated and organized. + biological_process + GO:0048815 + hermaphrodite genitalia morphogenesis + + + + + The process in which the anatomical structures of hermaphrodite genitalia are generated and organized. + GOC:ems + ISBN:0140512888 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the ocellus are generated and organized. The ocellus is a simple visual organ of insects. + biological_process + GO:0048816 + ocellus morphogenesis + + + + + The process in which the anatomical structures of the ocellus are generated and organized. The ocellus is a simple visual organ of insects. + http://fly.ebi.ac.uk/.bin/cvreport2?id=FBcv0004540 + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of hair follicle maturation. + down regulation of hair follicle maturation + down-regulation of hair follicle maturation + downregulation of hair follicle maturation + inhibition of hair follicle maturation + biological_process + GO:0048817 + negative regulation of hair follicle maturation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of hair follicle maturation. + GOC:devbiol + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of hair follicle maturation. + up regulation of hair follicle maturation + up-regulation of hair follicle maturation + upregulation of hair follicle maturation + activation of hair follicle maturation + stimulation of hair follicle maturation + biological_process + GO:0048818 + positive regulation of hair follicle maturation + + + + + Any process that activates or increases the frequency, rate or extent of hair follicle maturation. + GOC:devbiol + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of hair follicle maturation. + biological_process + GO:0048819 + regulation of hair follicle maturation + + + + + Any process that modulates the frequency, rate or extent of hair follicle maturation. + GOC:devbiol + + + + + + + + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for a hair follicle to attain its fully functional state. + biological_process + GO:0048820 + hair follicle maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for a hair follicle to attain its fully functional state. + GOC:devbiol + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of an erythrocyte over time, from its formation to the mature structure. + RBC development + red blood cell development + biological_process + GO:0048821 + erythrocyte development + + + + + The process whose specific outcome is the progression of an erythrocyte over time, from its formation to the mature structure. + GOC:devbiol + + + + + RBC development + CL:0000232 + + + + + red blood cell development + CL:0000232 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the inner ear over time, from its formation to the mature structure. + biological_process + GO:0048839 + inner ear development + + + + + The process whose specific outcome is the progression of the inner ear over time, from its formation to the mature structure. + GOC:sr + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the otolith over time, from its formation to the mature structure. + biological_process + GO:0048840 + otolith development + + + + + The process whose specific outcome is the progression of the otolith over time, from its formation to the mature structure. + GOC:sr + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of arterial blood vessels are generated and organized. Arteries are blood vessels that transport blood from the heart to the body and its organs. + arterial morphogenesis + arteriogenesis + biological_process + GO:0048844 + artery morphogenesis + + + + + The process in which the anatomical structures of arterial blood vessels are generated and organized. Arteries are blood vessels that transport blood from the heart to the body and its organs. + GOC:dsf + PMID:16740480 + + + + + arteriogenesis + GOC:mtg_heart + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of venous blood vessels are generated and organized. Veins are blood vessels that transport blood from the body and its organs to the heart. + vein morphogenesis + venous morphogenesis + biological_process + GO:0048845 + venous blood vessel morphogenesis + + + + + The process in which the anatomical structures of venous blood vessels are generated and organized. Veins are blood vessels that transport blood from the body and its organs to the heart. + GOC:dsf + PMID:16740480 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to adenohypophysis. This process pertains to the initial formation of a structure from unspecified parts. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus. + adenophysis biosynthesis + adenophysis formation + anterior pituitary biosynthesis + anterior pituitary formation + anterior pituitary gland biosynthesis + anterior pituitary gland formation + biological_process + GO:0048847 + adenohypophysis formation + + + + + The process that gives rise to adenohypophysis. This process pertains to the initial formation of a structure from unspecified parts. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus. + GOC:cvs + GOC:dgh + GOC:dph + GOC:jid + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the neurohypophysis are generated and organized. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation. + neurophysis morphogenesis + posterior pituitary gland morphogenesis + posterior pituitary morphogenesis + biological_process + GO:0048848 + neurohypophysis morphogenesis + + + + + The process in which the anatomical structures of the neurohypophysis are generated and organized. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to neurohypophysis. This process pertains to the initial formation of a structure from unspecified parts. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation. + neurophysis biosynthesis + neurophysis formation + posterior pituitary biosynthesis + posterior pituitary formation + posterior pituitary gland biosynthesis + posterior pituitary gland formation + biological_process + GO:0048849 + neurohypophysis formation + + + + + The process that gives rise to neurohypophysis. This process pertains to the initial formation of a structure from unspecified parts. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the hypophysis are generated and organized. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands. + pituitary gland morphogenesis + biological_process + GO:0048850 + hypophysis morphogenesis + + + + + The process in which the anatomical structures of the hypophysis are generated and organized. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the hypophysis are generated and organized. The hypophysis is an endocrine gland that secretes hormones that regulate many other glands. + hypophysis biosynthesis + pituitary gland biosynthesis + pituitary gland formation + biological_process + GO:0048851 + hypophysis formation + + + + + The process in which the anatomical structures of the hypophysis are generated and organized. The hypophysis is an endocrine gland that secretes hormones that regulate many other glands. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the diencephalon are generated and organized. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex. + biological_process + GO:0048852 + diencephalon morphogenesis + + + + + The process in which the anatomical structures of the diencephalon are generated and organized. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + ISBN:0838580343 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the forebrain are generated and organized. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions). + prosencephalon morphogenesis + biological_process + GO:0048853 + forebrain morphogenesis + + + + + The process in which the anatomical structures of the forebrain are generated and organized. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions). + GOC:cvs + GOC:dgh + GOC:dph + GOC:jid + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the brain are generated and organized. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.). + biological_process + GO:0048854 + brain morphogenesis + + + + + The process in which the anatomical structures of the brain are generated and organized. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.). + GOC:dgh + GOC:jid + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the adenohypophysis are generated and organized. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus. + adenophysis morphogenesis + anterior pituitary gland morphogenesis + anterior pituitary morphogenesis + biological_process + GO:0048855 + adenohypophysis morphogenesis + + + + + The process in which the anatomical structures of the adenohypophysis are generated and organized. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus. + GOC:cvs + GOC:dgh + GOC:dph + GOC:jid + + + + + + + + + + + + + + + + + + + + The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. + development of an anatomical structure + biological_process + GO:0048856 + + + + anatomical structure development + + + + + The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + The biological process whose specific outcome is the progression of a neural nucleus from its initial condition to its mature state. A neural nucleus is an anatomical structure consisting of a discrete aggregate of neuronal soma. + biological_process + GO:0048857 + neural nucleus development + + + + + The biological process whose specific outcome is the progression of a neural nucleus from its initial condition to its mature state. A neural nucleus is an anatomical structure consisting of a discrete aggregate of neuronal soma. + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of a cell projection are generated and organized. + biological_process + GO:0048858 + cell projection morphogenesis + + + + + The process in which the anatomical structures of a cell projection are generated and organized. + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + + + The process in which the limits of an anatomical structure are generated. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. + biological_process + GO:0048859 + formation of anatomical boundary + + + + + The process in which the limits of an anatomical structure are generated. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. + GO_REF:0000021 + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of a stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. + Wikipedia:Stem_cell_differentiation + biological_process + GO:0048863 + stem cell differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized features of a stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. + CL:0000034 + GOC:isa_complete + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the stem cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to its specific fate. + biological_process + GO:0048864 + stem cell development + + + + + The process whose specific outcome is the progression of the stem cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to its specific fate. + CL:0000034 + GOC:isa_complete + + + + + + + + + + A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition. + biological_process + GO:0048869 + cellular developmental process + + + + + A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition. + GOC:isa_complete + + + + + + + + + Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another. + https://github.com/geneontology/go-ontology/issues/19809 + cell locomotion + movement of a cell + biological_process + cell movement + GO:0048870 + + + + + cell motility + + + + + Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another. + GOC:dgh + GOC:dph + GOC:isa_complete + GOC:mlg + + + + + + + + + + Any process involved in the maintenance of an internal steady state at the level of the multicellular organism. + biological_process + GO:0048871 + multicellular organismal homeostasis + + + + + Any process involved in the maintenance of an internal steady state at the level of the multicellular organism. + GOC:isa_complete + + + + + + + + + Any biological process involved in the maintenance of the steady-state number of cells within a population of cells. + cell population homeostasis + homeostasis of cell number + biological_process + GO:0048872 + homeostasis of number of cells + + + + + Any biological process involved in the maintenance of the steady-state number of cells within a population of cells. + GOC:isa_complete + + + + + homeostasis of cell number + GOC:dph + + + + + + + + + + + + + + + + + + + + Any biological process involved in the maintenance of an internal steady state of a chemical. + biological_process + GO:0048878 + + chemical homeostasis + + + + + Any biological process involved in the maintenance of an internal steady state of a chemical. + GOC:isa_complete + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a sensory system over time from its formation to the mature structure. + biological_process + GO:0048880 + sensory system development + + + + + The process whose specific outcome is the progression of a sensory system over time from its formation to the mature structure. + GOC:dgh + + + + + + + + + The process whose specific outcome is the progression of the mechanosensory lateral line system over time, from its formation to the mature structure. The mechanosensory lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The neuromasts are innervated by several lateral line nerves, which project primarily to the hindbrain. The mechanosensory lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance. + LL system development + biological_process + GO:0048881 + mechanosensory lateral line system development + + + + + The process whose specific outcome is the progression of the mechanosensory lateral line system over time, from its formation to the mature structure. The mechanosensory lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The neuromasts are innervated by several lateral line nerves, which project primarily to the hindbrain. The mechanosensory lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance. + ISBN:0125296509 + + + + + LL system development + ISBN:0125296509 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the lateral line over time, from its formation to the mature structure. The lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line develops from cranial ectodermal placodes situated behind the ear and between the eye and ear. + LL development + biological_process + GO:0048882 + lateral line development + + + + + The process whose specific outcome is the progression of the lateral line over time, from its formation to the mature structure. The lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line develops from cranial ectodermal placodes situated behind the ear and between the eye and ear. + ISBN:0125296509 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the neuromast over time, from its formation to the mature structure. The neuromast is the sensory organ of the lateral line and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromasts are located superficially on the epithelium or in lateral line canals. + biological_process + GO:0048884 + neuromast development + + + + + The process whose specific outcome is the progression of the neuromast over time, from its formation to the mature structure. The neuromast is the sensory organ of the lateral line and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromasts are located superficially on the epithelium or in lateral line canals. + ISBN:0125296509 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of a neuromast hair cell. Hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons. + biological_process + GO:0048886 + neuromast hair cell differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized features of a neuromast hair cell. Hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons. + CL:0000856 + ISBN:0125296509 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the lateral line ganglion over time, from its formation to the mature structure. The lateral line ganglion develops from cranial ectodermal placodes situated between the eye and ear and behind the ear. + gLL ganglion development + biological_process + GO:0048890 + lateral line ganglion development + + + + + The process whose specific outcome is the progression of the lateral line ganglion over time, from its formation to the mature structure. The lateral line ganglion develops from cranial ectodermal placodes situated between the eye and ear and behind the ear. + ISBN:0125296509 + ISBN:0387968377 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the lateral line nerve over time, form its formation to the mature structure. Lateral line nerves project primarily to an octavolateralis column in the hindbrain that consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus. + nLL development + biological_process + GO:0048892 + lateral line nerve development + + + + + The process whose specific outcome is the progression of the lateral line nerve over time, form its formation to the mature structure. Lateral line nerves project primarily to an octavolateralis column in the hindbrain that consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus. + ISBN:0125296509 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the anterior lateral line system over time, from its formation to the mature structure. The anterior lateral line system develops from cranial ectodermal placodes, situated between the eye and the ear, that give rise to both the neuromasts and the anterior lateral line sensory nerves that innervate the neuromasts. The anterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians and are innervated by several lateral line nerves, which project to the hindbrain. The anterior lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance. + biological_process + ALL system development + GO:0048898 + anterior lateral line system development + + + + + The process whose specific outcome is the progression of the anterior lateral line system over time, from its formation to the mature structure. The anterior lateral line system develops from cranial ectodermal placodes, situated between the eye and the ear, that give rise to both the neuromasts and the anterior lateral line sensory nerves that innervate the neuromasts. The anterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians and are innervated by several lateral line nerves, which project to the hindbrain. The anterior lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance. + ISBN:0125296509 + PMID:15018940 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the anterior lateral line over time, from its formation to the mature structure. The anterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The anterior lateral line develops from cranial ectodermal placodes situated between the eye and ear. + anterior LL development + biological_process + GO:0048899 + anterior lateral line development + + + + + The process whose specific outcome is the progression of the anterior lateral line over time, from its formation to the mature structure. The anterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The anterior lateral line develops from cranial ectodermal placodes situated between the eye and ear. + ISBN:0125296509 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the anterior lateral line neuromast over time, from its formation to the mature structure. The neuromast is the sensory receptor of the anterior lateral line system and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromast are located superficially on the epithelium or in lateral line canals. + biological_process + GO:0048901 + anterior lateral line neuromast development + + + + + The process whose specific outcome is the progression of the anterior lateral line neuromast over time, from its formation to the mature structure. The neuromast is the sensory receptor of the anterior lateral line system and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromast are located superficially on the epithelium or in lateral line canals. + ISBN:0125296509 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the anterior lateral line ganglion over time, from its formation to the mature structure. The anterior lateral line ganglion develops from cranial ectodermal placodes situated between the eye and ear. + gALL development + biological_process + GO:0048907 + anterior lateral line ganglion development + + + + + The process whose specific outcome is the progression of the anterior lateral line ganglion over time, from its formation to the mature structure. The anterior lateral line ganglion develops from cranial ectodermal placodes situated between the eye and ear. + ISBN:0125296509 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the anterior lateral line nerve over time, form its formation to the mature structure. The anterior lateral line nerve contains efferent axons that innervate hair cells of the ALL and afferent axons that project to an octavolateralis column in the hindbrain. The octavolateralis column consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus. + GO:0021734 + ALLN development + nALL development + rostral lateral line nerve development + biological_process + GO:0048909 + anterior lateral line nerve development + + + + + The process whose specific outcome is the progression of the anterior lateral line nerve over time, form its formation to the mature structure. The anterior lateral line nerve contains efferent axons that innervate hair cells of the ALL and afferent axons that project to an octavolateralis column in the hindbrain. The octavolateralis column consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0125296509 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the posterior lateral line system over time, from its formation to the mature structure. The posterior lateral line system develops from cranial ectodermal placodes, situated behind the ear, that give rise to both the neuromasts and the posterior lateral line sensory nerves that innervate the neuromasts. The posterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The neuromasts are innervated by several lateral line nerves, which project primarily to the hindbrain. The posterior mechanosensory lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance. + biological_process + PLL + GO:0048915 + posterior lateral line system development + + + + + The process whose specific outcome is the progression of the posterior lateral line system over time, from its formation to the mature structure. The posterior lateral line system develops from cranial ectodermal placodes, situated behind the ear, that give rise to both the neuromasts and the posterior lateral line sensory nerves that innervate the neuromasts. The posterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The neuromasts are innervated by several lateral line nerves, which project primarily to the hindbrain. The posterior mechanosensory lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance. + ISBN:0125296509 + PMID:15018940 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the posterior lateral line over time, from its formation to the mature structure. The posterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the body and trunk of all fishes and most amphibians. The posterior lateral line develops from cranial ectodermal placodes situated behind the ear. + PLL development + biological_process + GO:0048916 + posterior lateral line development + + + + + The process whose specific outcome is the progression of the posterior lateral line over time, from its formation to the mature structure. The posterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the body and trunk of all fishes and most amphibians. The posterior lateral line develops from cranial ectodermal placodes situated behind the ear. + ISBN:0125296509 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the posterior lateral line ganglion over time, from its formation to the mature structure. The posterior lateral line ganglion develops from cranial ectodermal placodes situated behind the ear. + gPLL development + biological_process + GO:0048917 + posterior lateral line ganglion development + + + + + The process whose specific outcome is the progression of the posterior lateral line ganglion over time, from its formation to the mature structure. The posterior lateral line ganglion develops from cranial ectodermal placodes situated behind the ear. + ISBN:0125296509 + ISBN:0387968377 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the posterior lateral line nerve over time, from its formation to the mature structure. The posterior lateral line nerve innervates hair cells of the PLL and projects to an octavolateralis column in the hindbrain that consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus. + GO:0021733 + PLLN development + caudal lateral line nerve development + biological_process + GO:0048918 + posterior lateral line nerve development + + + + + The process whose specific outcome is the progression of the posterior lateral line nerve over time, from its formation to the mature structure. The posterior lateral line nerve innervates hair cells of the PLL and projects to an octavolateralis column in the hindbrain that consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus. + GOC:cls + GOC:dgh + GOC:dph + GOC:jid + GO_REF:0000021 + ISBN:0125296509 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the posterior lateral line neuromast over time, from its formation to the mature structure. The neuromast is the sensory receptor of the anterior lateral line system and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromast are located superficially on the epithelium or in lateral line canals. + biological_process + GO:0048919 + posterior lateral line neuromast development + + + + + The process whose specific outcome is the progression of the posterior lateral line neuromast over time, from its formation to the mature structure. The neuromast is the sensory receptor of the anterior lateral line system and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromast are located superficially on the epithelium or in lateral line canals. + ISBN:0125296509 + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the lateral line system over time, from its formation to the mature structure. The lateral line system is a network of sensory organs (neuromasts) and lateral line nerves located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line system develops from cranial ectodermal placodes situated between the eye and ear. + biological_process + GO:0048925 + lateral line system development + + + + + The process whose specific outcome is the progression of the lateral line system over time, from its formation to the mature structure. The lateral line system is a network of sensory organs (neuromasts) and lateral line nerves located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line system develops from cranial ectodermal placodes situated between the eye and ear. + GOC:dgh + ISBN:0125296509 + + + + + + + + + + + + + + + + + + + + The regulated release of catecholamines by a cell. The catecholamines are a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. + biological_process + GO:0050432 + catecholamine secretion + + + + + The regulated release of catecholamines by a cell. The catecholamines are a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. + GOC:ai + GOC:ef + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the regulated release of catecholamines. + biological_process + GO:0050433 + regulation of catecholamine secretion + + + + + Any process that modulates the frequency, rate or extent of the regulated release of catecholamines. + GOC:ai + + + + + + + + + + The chemical reactions and pathways resulting in the formation of chondroitin sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are chondroitin sulfate. Chondroitin sulfates are a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues; the repeat units consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate. + chondroitin sulfate proteoglycan anabolism + chondroitin sulfate proteoglycan biosynthesis + chondroitin sulfate proteoglycan formation + chondroitin sulfate proteoglycan synthesis + chondroitin sulphate proteoglycan biosynthesis + chondroitin sulphate proteoglycan biosynthetic process + biological_process + GO:0050650 + chondroitin sulfate proteoglycan biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of chondroitin sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are chondroitin sulfate. Chondroitin sulfates are a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues; the repeat units consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate. + GOC:ai + + + + + + + + + The chemical reactions and pathways involving chondroitin sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are chondroitin sulfate. Chondroitin sulfates are a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues; the repeat units consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate. + chondroitin sulfate proteoglycan metabolism + chondroitin sulphate proteoglycan metabolic process + chondroitin sulphate proteoglycan metabolism + biological_process + GO:0050654 + chondroitin sulfate proteoglycan metabolic process + + + + + The chemical reactions and pathways involving chondroitin sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are chondroitin sulfate. Chondroitin sulfates are a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues; the repeat units consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate. + GOC:ai + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of lymphocyte proliferation. + biological_process + GO:0050670 + regulation of lymphocyte proliferation + + + + + Any process that modulates the frequency, rate or extent of lymphocyte proliferation. + GOC:ai + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the rate or extent of lymphocyte proliferation. + up regulation of lymphocyte proliferation + up-regulation of lymphocyte proliferation + upregulation of lymphocyte proliferation + activation of lymphocyte proliferation + stimulation of lymphocyte proliferation + biological_process + GO:0050671 + positive regulation of lymphocyte proliferation + + + + + Any process that activates or increases the rate or extent of lymphocyte proliferation. + GOC:ai + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the rate or extent of lymphocyte proliferation. + down regulation of lymphocyte proliferation + down-regulation of lymphocyte proliferation + downregulation of lymphocyte proliferation + inhibition of lymphocyte proliferation + biological_process + GO:0050672 + negative regulation of lymphocyte proliferation + + + + + Any process that stops, prevents or reduces the rate or extent of lymphocyte proliferation. + GOC:ai + + + + + + + + + + + + + + + + + + + + The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population. Epithelial cells make up the epithelium, the covering of internal and external surfaces of the body, including the lining of vessels and other small cavities. It consists of cells joined by small amounts of cementing substances. + biological_process + GO:0050673 + epithelial cell proliferation + + + + + The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population. Epithelial cells make up the epithelium, the covering of internal and external surfaces of the body, including the lining of vessels and other small cavities. It consists of cells joined by small amounts of cementing substances. + ISBN:0721662544 + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of epithelial cell proliferation. + biological_process + GO:0050678 + regulation of epithelial cell proliferation + + + + + Any process that modulates the frequency, rate or extent of epithelial cell proliferation. + GOC:ai + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the rate or extent of epithelial cell proliferation. + up regulation of epithelial cell proliferation + up-regulation of epithelial cell proliferation + upregulation of epithelial cell proliferation + activation of epithelial cell proliferation + stimulation of epithelial cell proliferation + biological_process + GO:0050679 + positive regulation of epithelial cell proliferation + + + + + Any process that activates or increases the rate or extent of epithelial cell proliferation. + GOC:ai + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation. + down regulation of epithelial cell proliferation + down-regulation of epithelial cell proliferation + downregulation of epithelial cell proliferation + inhibition of epithelial cell proliferation + biological_process + GO:0050680 + negative regulation of epithelial cell proliferation + + + + + Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation. + GOC:ai + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell. + biological_process + GO:0050708 + regulation of protein secretion + + + + + Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell. + GOC:ai + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell. + down regulation of protein secretion + down-regulation of protein secretion + downregulation of protein secretion + inhibition of protein secretion + biological_process + GO:0050709 + negative regulation of protein secretion + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell. + GOC:ai + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell. + up regulation of protein secretion + up-regulation of protein secretion + upregulation of protein secretion + activation of protein secretion + stimulation of protein secretion + biological_process + GO:0050714 + positive regulation of protein secretion + + + + + Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell. + GOC:ai + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. + biological_process + GO:0050727 + regulation of inflammatory response + + + + + Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. + GOC:ai + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response. + GO:0030236 + anti-inflammatory response + down regulation of inflammatory response + down-regulation of inflammatory response + downregulation of inflammatory response + inhibition of inflammatory response + biological_process + GO:0050728 + negative regulation of inflammatory response + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response. + GOC:ai + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the inflammatory response. + up regulation of inflammatory response + up-regulation of inflammatory response + upregulation of inflammatory response + activation of inflammatory response + stimulation of inflammatory response + biological_process + GO:0050729 + positive regulation of inflammatory response + + + + + Any process that activates or increases the frequency, rate or extent of the inflammatory response. + GOC:ai + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine. + biological_process + GO:0050730 + regulation of peptidyl-tyrosine phosphorylation + + + + + Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine. + GOC:ai + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine. + up regulation of peptidyl-tyrosine phosphorylation + up-regulation of peptidyl-tyrosine phosphorylation + upregulation of peptidyl-tyrosine phosphorylation + activation of peptidyl-tyrosine phosphorylation + stimulation of peptidyl-tyrosine phosphorylation + biological_process + GO:0050731 + positive regulation of peptidyl-tyrosine phosphorylation + + + + + Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine. + GOC:ai + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine. + down regulation of peptidyl-tyrosine phosphorylation + down-regulation of peptidyl-tyrosine phosphorylation + downregulation of peptidyl-tyrosine phosphorylation + inhibition of peptidyl-tyrosine phosphorylation + biological_process + GO:0050732 + negative regulation of peptidyl-tyrosine phosphorylation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine. + GOC:ai + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids. + regulation of lipoprotein metabolism + biological_process + GO:0050746 + regulation of lipoprotein metabolic process + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids. + GOC:ai + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids. + positive regulation of lipoprotein metabolism + up regulation of lipoprotein metabolic process + up-regulation of lipoprotein metabolic process + upregulation of lipoprotein metabolic process + activation of lipoprotein metabolic process + stimulation of lipoprotein metabolic process + biological_process + GO:0050747 + positive regulation of lipoprotein metabolic process + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids. + GOC:ai + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids. + down regulation of lipoprotein metabolic process + down-regulation of lipoprotein metabolic process + downregulation of lipoprotein metabolic process + negative regulation of lipoprotein metabolism + inhibition of lipoprotein metabolic process + biological_process + GO:0050748 + negative regulation of lipoprotein metabolic process + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids. + GOC:ai + + + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of neurogenesis, the generation of cells in the nervous system. + biological_process + GO:0050767 + regulation of neurogenesis + + + + + Any process that modulates the frequency, rate or extent of neurogenesis, the generation of cells in the nervous system. + GOC:ai + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system. + down regulation of neurogenesis + down-regulation of neurogenesis + downregulation of neurogenesis + inhibition of neurogenesis + biological_process + GO:0050768 + negative regulation of neurogenesis + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system. + GOC:ai + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system. + up regulation of neurogenesis + up-regulation of neurogenesis + upregulation of neurogenesis + activation of neurogenesis + stimulation of neurogenesis + biological_process + GO:0050769 + positive regulation of neurogenesis + + + + + Any process that activates or increases the frequency, rate or extent of neurogenesis, the generation of cells within the nervous system. + GOC:ai + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron. + biological_process + GO:0050770 + regulation of axonogenesis + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron. + GOC:ai + + + + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of axonogenesis. + down regulation of axonogenesis + down-regulation of axonogenesis + downregulation of axonogenesis + inhibition of axonogenesis + biological_process + GO:0050771 + negative regulation of axonogenesis + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of axonogenesis. + GOC:ai + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of axonogenesis. + up regulation of axonogenesis + up-regulation of axonogenesis + upregulation of axonogenesis + activation of axonogenesis + stimulation of axonogenesis + biological_process + GO:0050772 + positive regulation of axonogenesis + + + + + Any process that activates or increases the frequency, rate or extent of axonogenesis. + GOC:ai + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of dendrite development. + biological_process + GO:0050773 + regulation of dendrite development + + + + + Any process that modulates the frequency, rate or extent of dendrite development. + GOC:ai + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite morphogenesis. + down regulation of dendrite morphogenesis + down-regulation of dendrite morphogenesis + downregulation of dendrite morphogenesis + inhibition of dendrite morphogenesis + biological_process + GO:0050774 + negative regulation of dendrite morphogenesis + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite morphogenesis. + GOC:ai + + + + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of dendrite morphogenesis. + up regulation of dendrite morphogenesis + up-regulation of dendrite morphogenesis + upregulation of dendrite morphogenesis + activation of dendrite morphogenesis + stimulation of dendrite morphogenesis + biological_process + GO:0050775 + positive regulation of dendrite morphogenesis + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that activates or increases the frequency, rate or extent of dendrite morphogenesis. + GOC:ai + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. + biological_process + GO:0050776 + regulation of immune response + + + + + Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. + GOC:ai + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. + down regulation of immune response + down-regulation of immune response + downregulation of immune response + inhibition of immune response + biological_process + GO:0050777 + negative regulation of immune response + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. + GOC:ai + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. + up regulation of immune response + up-regulation of immune response + upregulation of immune response + stimulation of immune response + biological_process + GO:0050778 + positive regulation of immune response + + + + + Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus. + GOC:ai + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. + GO:0050791 + regulation of physiological process + biological_process + GO:0050789 + + + + regulation of biological process + + + + + Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule. + GOC:ai + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that modulates the activity of an enzyme. + GO:0048552 + regulation of enzyme activity + regulation of metalloenzyme activity + biological_process + GO:0050790 + + regulation of catalytic activity + + + + + Any process that modulates the activity of an enzyme. + GOC:ai + GOC:ebc + GOC:vw + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). + biological_process + GO:0050793 + regulation of developmental process + + + + + Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). + GOC:go_curators + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. + GO:0051244 + regulation of cellular physiological process + biological_process + GO:0050794 + + regulation of cellular process + + + + + Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli. + regulation of behaviour + biological_process + GO:0050795 + regulation of behavior + + + + + Any process that modulates the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli. + GOC:go_curators + GOC:pr + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the regulated release of insulin. + biological_process + GO:0050796 + regulation of insulin secretion + + + + + Any process that modulates the frequency, rate or extent of the regulated release of insulin. + GOC:ai + + + + + + + + + + + + + + + + + + + Any process involved in the maintenance of an internal steady state of ions within an organism or cell. + GO:2000021 + biological_process + electrolyte homeostasis + negative regulation of crystal formation + regulation of ion homeostasis + GO:0050801 + ion homeostasis + + + + + Any process involved in the maintenance of an internal steady state of ions within an organism or cell. + GOC:ai + + + + + + + + + + + + + + + + + + + + + + The part of the circadian sleep/wake cycle where the organism is asleep. + biological_process + GO:0050802 + circadian sleep/wake cycle, sleep + + + + + The part of the circadian sleep/wake cycle where the organism is asleep. + GOC:ai + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. + regulation of steroid anabolism + regulation of steroid biosynthesis + regulation of steroid formation + regulation of steroid synthesis + regulation of steroidogenesis + biological_process + GO:0050810 + regulation of steroid biosynthetic process + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus. + GOC:ai + + + + + + + + + The process in which a fluid solution, or part of it, changes into a solid or semisolid mass. + clotting + biological_process + GO:0050817 + + coagulation + + + + + The process in which a fluid solution, or part of it, changes into a solid or semisolid mass. + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of coagulation, the process in which a fluid solution, or part of it, changes into a solid or semisolid mass. + regulation of clotting + biological_process + GO:0050818 + regulation of coagulation + + + + + Any process that modulates the frequency, rate or extent of coagulation, the process in which a fluid solution, or part of it, changes into a solid or semisolid mass. + GOC:ai + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of coagulation. + down regulation of coagulation + down-regulation of coagulation + downregulation of coagulation + negative regulation of clotting + inhibition of coagulation + biological_process + anticoagulant activity + GO:0050819 + negative regulation of coagulation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of coagulation. + GOC:ai + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of coagulation. + positive regulation of clotting + up regulation of coagulation + up-regulation of coagulation + upregulation of coagulation + activation of coagulation + stimulation of coagulation + biological_process + GO:0050820 + positive regulation of coagulation + + + + + Any process that activates or increases the frequency, rate or extent of coagulation. + GOC:ai + + + + + + + + + + + + + + + + + + + Reactions triggered in response to the presence of a fungus that act to protect the cell or organism. + GO:0009623 + GO:0009817 + GO:0042831 + defence response to fungi + defence response to fungus + defense response to fungi + defense response to fungus, incompatible interaction + resistance response to pathogenic fungi + resistance response to pathogenic fungus + response to parasitic fungi + response to parasitic fungus + biological_process + GO:0050832 + defense response to fungus + + + + + Reactions triggered in response to the presence of a fungus that act to protect the cell or organism. + GOC:ai + + + + + + + + + Binding to a cell adhesion molecule. + CAM binding + molecular_function + adhesive extracellular matrix constituent + cell adhesion molecule activity + cell adhesion receptor activity + GO:0050839 + cell adhesion molecule binding + + + + + Binding to a cell adhesion molecule. + GOC:ai + + + + + + + + + + + + + + + + + + + + Binding to a component of the extracellular matrix. + extracellular matrix constituent binding + molecular_function + adhesive extracellular matrix constituent + GO:0050840 + + + extracellular matrix binding + + + + + Binding to a component of the extracellular matrix. + GOC:ai + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of T cell activation. + regulation of T lymphocyte activation + regulation of T-cell activation + regulation of T-lymphocyte activation + biological_process + GO:0050863 + regulation of T cell activation + + + + + Any process that modulates the frequency, rate or extent of T cell activation. + GOC:ai + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of B cell activation. + regulation of B lymphocyte activation + regulation of B-cell activation + regulation of B-lymphocyte activation + biological_process + GO:0050864 + regulation of B cell activation + + + + + Any process that modulates the frequency, rate or extent of B cell activation. + GOC:ai + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand. + biological_process + GO:0050865 + regulation of cell activation + + + + + Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand. + GOC:ai + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of cell activation. + down regulation of cell activation + down-regulation of cell activation + downregulation of cell activation + inhibition of cell activation + biological_process + GO:0050866 + negative regulation of cell activation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of cell activation. + GOC:ai + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of activation. + up regulation of cell activation + up-regulation of cell activation + upregulation of cell activation + activation of cell activation + stimulation of cell activation + biological_process + GO:0050867 + positive regulation of cell activation + + + + + Any process that activates or increases the frequency, rate or extent of activation. + GOC:ai + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of T cell activation. + down regulation of T cell activation + down-regulation of T cell activation + downregulation of T cell activation + negative regulation of T lymphocyte activation + negative regulation of T-cell activation + negative regulation of T-lymphocyte activation + inhibition of T cell activation + biological_process + GO:0050868 + negative regulation of T cell activation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of T cell activation. + GOC:ai + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of B cell activation. + down regulation of B cell activation + down-regulation of B cell activation + downregulation of B cell activation + negative regulation of B lymphocyte activation + negative regulation of B-cell activation + negative regulation of B-lymphocyte activation + inhibition of B cell activation + biological_process + GO:0050869 + negative regulation of B cell activation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of B cell activation. + GOC:ai + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of T cell activation. + positive regulation of T lymphocyte activation + positive regulation of T-cell activation + positive regulation of T-lymphocyte activation + up regulation of T cell activation + up-regulation of T cell activation + upregulation of T cell activation + activation of T cell activation + stimulation of T cell activation + biological_process + GO:0050870 + positive regulation of T cell activation + + + + + Any process that activates or increases the frequency, rate or extent of T cell activation. + GOC:ai + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of B cell activation. + positive regulation of B lymphocyte activation + positive regulation of B-cell activation + positive regulation of B-lymphocyte activation + up regulation of B cell activation + up-regulation of B cell activation + upregulation of B cell activation + activation of B cell activation + stimulation of B cell activation + biological_process + GO:0050871 + positive regulation of B cell activation + + + + + Any process that activates or increases the frequency, rate or extent of B cell activation. + GOC:ai + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of a white adipocyte, an animal connective tissue cell involved in energy storage. White adipocytes have cytoplasmic lipids arranged in a unique vacuole. + white adipocyte cell differentiation + white adipocyte differentiation + biological_process + GO:0050872 + white fat cell differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized features of a white adipocyte, an animal connective tissue cell involved in energy storage. White adipocytes have cytoplasmic lipids arranged in a unique vacuole. + PMID:12508945 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria. + + brown adipocyte cell differentiation + brown adipocyte differentiation + biological_process + GO:0050873 + brown fat cell differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria. + PMID:12588810 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A organ system process carried out by any of the organs or tissues of neurological system. + https://github.com/geneontology/go-ontology/issues/13824 + neurological system process + neurophysiological process + biological_process + pan-neural process + GO:0050877 + + + + + + nervous system process + + + + + A organ system process carried out by any of the organs or tissues of neurological system. + GOC:ai + GOC:mtg_cardio + + + + + + + + + + + + + + + + + + + Any process that modulates the levels of body fluids. + biological_process + GO:0050878 + + regulation of body fluid levels + + + + + Any process that modulates the levels of body fluids. + GOC:ai + GOC:dph + GOC:tb + + + + + + + + + Any physiological process involved in changing the position of a multicellular organism or an anatomical part of a multicellular organism. + biological_process + GO:0050879 + + multicellular organismal movement + + + + + Any physiological process involved in changing the position of a multicellular organism or an anatomical part of a multicellular organism. + GOC:dph + GOC:mtg_muscle + GOC:tb + + + + + + + + + + The movement of an organism or part of an organism using mechanoreceptors, the nervous system, striated muscle and/or the skeletal system. + biological_process + GO:0050881 + musculoskeletal movement + + + + + The movement of an organism or part of an organism using mechanoreceptors, the nervous system, striated muscle and/or the skeletal system. + GOC:dph + + + + + + + + + + + + + + + Any process in which an organism voluntarily modulates its posture, the alignment of its anatomical parts. + regulation of posture + biological_process + GO:0050884 + neuromuscular process controlling posture + + + + + Any process in which an organism voluntarily modulates its posture, the alignment of its anatomical parts. + GOC:dph + GOC:tb + + + + + + + + + + + + + + + Any process that an organism uses to control its balance, the orientation of the organism (or the head of the organism) in relation to the source of gravity. In humans and animals, balance is perceived through visual cues, the labyrinth system of the inner ears and information from skin pressure receptors and muscle and joint receptors. + biological_process + regulation of balance + GO:0050885 + neuromuscular process controlling balance + + + + + Any process that an organism uses to control its balance, the orientation of the organism (or the head of the organism) in relation to the source of gravity. In humans and animals, balance is perceived through visual cues, the labyrinth system of the inner ears and information from skin pressure receptors and muscle and joint receptors. + GOC:ai + GOC:dph + + + + + + + + + The process that involves the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system. + endocrine physiological process + endocrine physiology + biological_process + GO:0050886 + + + endocrine process + + + + + The process that involves the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system. + ISBN:0721662544 + + + + + + + + + The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory. + Wikipedia:Cognition + biological_process + GO:0050890 + + cognition + + + + + The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory. + ISBN:0721619908 + + + + + + + + + + + + + + + + + + + + + + Any process involved in the maintenance of an internal steady state of water within a tissue, organ, or a multicellular organism. + biological_process + body fluid osmoregulation + GO:0050891 + multicellular organismal water homeostasis + + + + + Any process involved in the maintenance of an internal steady state of water within a tissue, organ, or a multicellular organism. + GOC:dph + GOC:tb + + + + + body fluid osmoregulation + GOC:dph + GOC:tb + + + + + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. + GO:0051869 + physiological response to stimulus + biological_process + GO:0050896 + + + + + + + Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. + response to stimulus + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. + GOC:ai + GOC:bf + + + + + + + + + + + + + + + + + + + + + The movement of a leukocyte within or between different tissues and organs of the body. + immune cell migration + immune cell trafficking + leucocyte migration + leucocyte trafficking + leukocyte trafficking + biological_process + GO:0050900 + leukocyte migration + + + + + The movement of a leukocyte within or between different tissues and organs of the body. + GOC:add + ISBN:0781735149 + PMID:14680625 + PMID:14708592 + PMID:7507411 + PMID:8600538 + + + + + + + + + Any process pertaining to the functions of the nervous and muscular systems of an organism. + neuromotor process + neuromuscular physiological process + biological_process + GO:0050905 + neuromuscular process + + + + + Any process pertaining to the functions of the nervous and muscular systems of an organism. + GOC:ai + + + + + + + + + + + + + + + + + + + + The series of events involved in sensory perception in which a sensory stimulus is received and converted into a molecular signal. + Wikipedia:Transduction_(physiology) + sensory detection of stimulus + sensory perception, sensory transduction of stimulus + sensory perception, stimulus detection + sensory transduction + biological_process + GO:0050906 + detection of stimulus involved in sensory perception + + + + + The series of events involved in sensory perception in which a sensory stimulus is received and converted into a molecular signal. + GOC:ai + GOC:dos + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + The series of events in which a chemical stimulus is received and converted into a molecular signal as part of sensory perception. + sensory detection of chemical stimulus + sensory detection of chemical stimulus during sensory perception + sensory perception, sensory detection of chemical stimulus + sensory perception, sensory transduction of chemical stimulus + sensory transduction of chemical stimulus + sensory transduction of chemical stimulus during sensory perception + biological_process + GO:0050907 + detection of chemical stimulus involved in sensory perception + + + + + The series of events in which a chemical stimulus is received and converted into a molecular signal as part of sensory perception. + GOC:ai + GOC:dos + + + + + + + + + + + + + + + + + + + + + The series of events involved in visual perception in which a light stimulus is received and converted into a molecular signal. + sensory detection of light during visual perception + sensory detection of light stimulus during visual perception + sensory transduction of light during visual perception + sensory transduction of light stimulus during visual perception + visual perception, detection of light stimulus + visual perception, sensory transduction during perception of light + visual perception, sensory transduction of light stimulus + biological_process + GO:0050908 + detection of light stimulus involved in visual perception + + + + + The series of events involved in visual perception in which a light stimulus is received and converted into a molecular signal. + GOC:ai + GOC:dos + + + + + + + + + The series of events required for an organism to receive a gustatory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Gustation involves the direct detection of chemical composition, usually through contact with chemoreceptor cells. This is a neurological process. + Wikipedia:Taste + gustation + sense of taste + taste + taste perception + biological_process + GO:0050909 + sensory perception of taste + + + + + The series of events required for an organism to receive a gustatory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Gustation involves the direct detection of chemical composition, usually through contact with chemoreceptor cells. This is a neurological process. + GOC:ai + + + + + + + + + + + + + + + + + + + + + The series of events involved in the perception of sound vibration in which the vibration is received and converted into a molecular signal. + GO:0009592 + GO:0055128 + detection of sound + hearing, sensory transduction of sound + perception of sound, detection of mechanical stimulus + perception of sound, sensory detection of mechanical stimulus + perception of sound, sensory transduction of mechanical stimulus + sensory detection of mechanical stimulus during perception of sound + sensory transduction of mechanical stimulus during perception of sound + sensory transduction of sound + biological_process + GO:0050910 + detection of mechanical stimulus involved in sensory perception of sound + + + + + The series of events involved in the perception of sound vibration in which the vibration is received and converted into a molecular signal. + GOC:ai + + + + + + + + + + + + + + + + + + + + The series of events involved in the perception of smell in which an olfactory chemical stimulus is received and converted into a molecular signal. + perception of smell, detection of chemical stimulus + perception of smell, sensory detection of chemical stimulus + perception of smell, sensory transduction of chemical stimulus + sensory detection of chemical stimulus during perception of smell + sensory detection of scent + sensory detection of smell + sensory transduction of chemical stimulus during perception of smell + sensory transduction of scent + sensory transduction of smell + biological_process + GO:0050911 + detection of chemical stimulus involved in sensory perception of smell + + + + + The series of events involved in the perception of smell in which an olfactory chemical stimulus is received and converted into a molecular signal. + GOC:ai + + + + + + + + + + + + + + + + + + + + The series of events involved in the perception of taste in which a gustatory chemical stimulus is received and converted into a molecular signal. + taste perception + perception of taste, detection of chemical stimulus + perception of taste, sensory detection of chemical stimulus + perception of taste, sensory transduction of chemical stimulus + sensory detection of chemical stimulus during perception of taste + sensory detection of taste + sensory transduction of chemical stimulus during perception of taste + sensory transduction of taste + biological_process + GO:0050912 + detection of chemical stimulus involved in sensory perception of taste + + + + + The series of events involved in the perception of taste in which a gustatory chemical stimulus is received and converted into a molecular signal. + GOC:ai + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires the specialized features of a pigmented cell, such as a melanocyte. + GO:0043357 + GO:0043358 + chromatophore differentiation + pigmented cell differentiation + biological_process + GO:0050931 + Note that the chromatophore mentioned here is distinct from the pigment bearing structure found in certain photosynthetic bacteria and cyanobacteria. It is also different from the plant chromoplast, which is also sometimes called a chromatophore. + pigment cell differentiation + + + + + The process in which a relatively unspecialized cell acquires the specialized features of a pigmented cell, such as a melanocyte. + GOC:dgh + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of pigmented cell differentiation. + biological_process + GO:0050932 + regulation of pigment cell differentiation + + + + + Any process that modulates the frequency, rate or extent of pigmented cell differentiation. + GOC:ai + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of pigment cell differentiation. + down regulation of pigment cell differentiation + down-regulation of pigment cell differentiation + downregulation of pigment cell differentiation + inhibition of pigment cell differentiation + biological_process + GO:0050941 + negative regulation of pigment cell differentiation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of pigment cell differentiation. + GOC:ai + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of pigment cell differentiation. + up regulation of pigment cell differentiation + up-regulation of pigment cell differentiation + upregulation of pigment cell differentiation + activation of pigment cell differentiation + stimulation of pigment cell differentiation + biological_process + GO:0050942 + positive regulation of pigment cell differentiation + + + + + Any process that activates or increases the frequency, rate or extent of pigment cell differentiation. + GOC:ai + + + + + + + + + The series of events required for an organism to receive a sensory temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. + sensory perception of thermal stimulus + biological_process + GO:0050951 + sensory perception of temperature stimulus + + + + + The series of events required for an organism to receive a sensory temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. + GOC:ai + + + + + + + + + The series of events required for an organism to receive a sensory electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. + biological_process + GO:0050952 + sensory perception of electrical stimulus + + + + + The series of events required for an organism to receive a sensory electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. + GOC:ai + + + + + + + + + The series of events required for an organism to receive a sensory light stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. + biological_process + GO:0050953 + sensory perception of light stimulus + + + + + The series of events required for an organism to receive a sensory light stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. + GOC:ai + + + + + + + + + The series of events required for an organism to receive a sensory mechanical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. + mechanosensory perception + perception of mechanical stimulus + biological_process + chemi-mechanical coupling + GO:0050954 + sensory perception of mechanical stimulus + + + + + The series of events required for an organism to receive a sensory mechanical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. + GOC:ai + + + + + + + + + The series of events required for an organism to receive an electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. Many fish possess an electroception sense; for example, the electric eel uses low voltage pulses of electricity for navigation and prey location. + Wikipedia:Electroreception + electroception sense + electroceptive sense + biological_process + GO:0050956 + electroception + + + + + The series of events required for an organism to receive an electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. Many fish possess an electroception sense; for example, the electric eel uses low voltage pulses of electricity for navigation and prey location. + GOC:ai + PMID:10210663 + Wikipedia:Electroreception + + + + + + + + + + + + + + + The series of events required for an organism to receive an orientational stimulus, convert it to a molecular signal, and recognize and characterize the signal. Equilibrioception refers to a combination of processes by which an organism can perceive its orientation with respect to gravity. In animals, stimuli come from labyrinth system of the inner ears, monitoring the direction of motion; visual stimuli, with information on orientation and motion; pressure receptors, which tell the organism which body surfaces are in contact with the ground; and proprioceptive cues, which report which parts of the body are in motion. + Wikipedia:Equilibrioception + sensory perception of orientation with respect to gravity + biological_process + GO:0050957 + equilibrioception + + + + + The series of events required for an organism to receive an orientational stimulus, convert it to a molecular signal, and recognize and characterize the signal. Equilibrioception refers to a combination of processes by which an organism can perceive its orientation with respect to gravity. In animals, stimuli come from labyrinth system of the inner ears, monitoring the direction of motion; visual stimuli, with information on orientation and motion; pressure receptors, which tell the organism which body surfaces are in contact with the ground; and proprioceptive cues, which report which parts of the body are in motion. + http://www.medterms.com + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Echolocation is the method used by some animals (e.g. bats, dolphins and some whales) to determine the location of something by measuring the time it takes for an echo to return from it. These animals emit sound waves and listen for the echo, calculating the distance to the object from the time lapse between sound emission and the echo returning. + + + Wikipedia:Echolocation + biological sonar + perception of environment using reflected sound waves + biological_process + GO:0050959 + echolocation + + + + + + + + + + + + + + + PMID:34140356 + + + + + + + + + + + + + + + PMID:34140356 + + + + + + + + + + + + + + + PMID:34140356 + + + + + + + + + + + + + + + PMID:34140356 + + + + + + + + + + + PMID:34140356 + + + + + + + + + + + PMID:34140356 + + + + + Echolocation is the method used by some animals (e.g. bats, dolphins and some whales) to determine the location of something by measuring the time it takes for an echo to return from it. These animals emit sound waves and listen for the echo, calculating the distance to the object from the time lapse between sound emission and the echo returning. + PMID:16005275 + Wikipedia:Animal_echolocation + + + + + + PMID:34140356 + + + + + + PMID:34140356 + + + + + biological sonar + https://en.wikipedia.org/wiki/Animal_echolocation + + + + + + + + + + + + + + + + + + + + + + + + + + + The series of events in which a temperature stimulus is received and converted into a molecular signal as part of sensory perception. + sensory detection of temperature stimulus + sensory detection of temperature stimulus during sensory perception + sensory detection of thermal stimulus during sensory perception + sensory perception, sensory detection of temperature stimulus + sensory perception, sensory detection of thermal stimulus + sensory perception, sensory transduction of temperature stimulus + sensory perception, sensory transduction of thermal stimulus + sensory transduction of temperature stimulus + sensory transduction of temperature stimulus during sensory perception + sensory transduction of thermal stimulus during sensory perception + sensory detection of heat stimulus during sensory perception + sensory perception, sensory detection of heat stimulus + sensory perception, sensory transduction of heat stimulus + sensory transduction of heat stimulus during sensory perception + biological_process + GO:0050961 + detection of temperature stimulus involved in sensory perception + + + + + The series of events in which a temperature stimulus is received and converted into a molecular signal as part of sensory perception. + GOC:ai + GOC:dos + + + + + + + + + + + + + + + + + + + + + + + + + + + The series of events in which a light stimulus is received by a cell and converted into a molecular signal as part of the sensory perception of light. + sensory detection of light stimulus + sensory detection of light stimulus during sensory perception + sensory perception, sensory detection of light stimulus + sensory perception, sensory transduction of light stimulus + sensory transduction of light stimulus + sensory transduction of light stimulus during sensory perception + biological_process + GO:0050962 + detection of light stimulus involved in sensory perception + + + + + The series of events in which a light stimulus is received by a cell and converted into a molecular signal as part of the sensory perception of light. + GOC:ai + GOC:dos + + + + + + + + + + + + + + + + + + + + + + + + + + + The series of events in which an electrical stimulus is received by a cell and converted into a molecular signal as part of sensory perception. + sensory detection of electrical stimulus + sensory detection of electrical stimulus during sensory perception + sensory perception, sensory detection of electrical stimulus + sensory perception, sensory transduction of electrical stimulus + sensory transduction of electrical stimulus + sensory transduction of electrical stimulus during sensory perception + biological_process + GO:0050963 + detection of electrical stimulus involved in sensory perception + + + + + The series of events in which an electrical stimulus is received by a cell and converted into a molecular signal as part of sensory perception. + GOC:ai + GOC:dos + + + + + + + + + + + + + + + + + + + + The series of events that contribute to electroception in which an electrical stimulus is received and converted into a molecular signal. + electroception, detection of electrical stimulus + electroception, sensory detection of electrical stimulus + electroception, sensory transduction + electroception, sensory transduction of electrical stimulus + biological_process + detection of electrical stimulus during electroreception + sensory detection of electrical stimulus during electroception + sensory transduction of electrical stimulus during electroception + GO:0050964 + detection of electrical stimulus involved in electroception + + + + + The series of events that contribute to electroception in which an electrical stimulus is received and converted into a molecular signal. + GOC:ai + GOC:dos + + + + + detection of electrical stimulus during electroreception + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + The series of events involved in the perception of pain in which a temperature stimulus is received and converted into a molecular signal. + perception of pain, detection of temperature stimulus + perception of pain, sensory detection of temperature stimulus + perception of pain, sensory transduction of temperature stimulus + sensory detection of temperature stimulus during perception of pain + sensory detection of thermal stimulus during sensory perception of pain + sensory perception of pain, sensory detection of thermal stimulus + sensory perception of pain, sensory transduction of thermal stimulus + sensory transduction of temperature stimulus during perception of pain + sensory transduction of thermal stimulus during sensory perception of pain + biological_process + thermal nociception + GO:0050965 + detection of temperature stimulus involved in sensory perception of pain + + + + + The series of events involved in the perception of pain in which a temperature stimulus is received and converted into a molecular signal. + GOC:ai + GOC:dos + + + + + thermal nociception + GOC:pr + + + + + + + + + + + + + + + + + + + + The series of events involved in the perception of pain in which a mechanical stimulus is received and converted into a molecular signal. + perception of pain, detection of mechanical stimulus + perception of pain, sensory detection of mechanical stimulus + perception of pain, sensory transduction of mechanical stimulus + sensory detection of mechanical stimulus during perception of pain + sensory transduction of mechanical stimulus during perception of pain + biological_process + mechanical nociception + GO:0050966 + detection of mechanical stimulus involved in sensory perception of pain + + + + + The series of events involved in the perception of pain in which a mechanical stimulus is received and converted into a molecular signal. + GOC:ai + GOC:dos + + + + + mechanical nociception + GOC:pr + + + + + + + + + + + + + + + + + + + + The series of events that contribute to the perception of pain in which an electrical stimulus is received and converted into a molecular signal. + perception of pain, detection of electrical stimulus + perception of pain, sensory detection of electrical stimulus + perception of pain, sensory transduction of electrical stimulus + biological_process + detection of electrical stimulus during sensory perception of pain + sensory detection of electrical stimulus during perception of pain + sensory transduction of electrical stimulus during perception of pain + GO:0050967 + detection of electrical stimulus involved in sensory perception of pain + + + + + The series of events that contribute to the perception of pain in which an electrical stimulus is received and converted into a molecular signal. + GOC:ai + GOC:dos + GOC:dph + GOC:tb + + + + + detection of electrical stimulus during sensory perception of pain + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + The series of events involved in the perception of pain in which a chemical stimulus is received and converted into a molecular signal. + perception of pain, detection of chemical stimulus + perception of pain, sensory detection of chemical stimulus + perception of pain, sensory transduction of chemical stimulus + sensory detection of chemical stimulus during perception of pain + sensory transduction of chemical stimulus during perception of pain + biological_process + chemical nociception + GO:0050968 + detection of chemical stimulus involved in sensory perception of pain + + + + + The series of events involved in the perception of pain in which a chemical stimulus is received and converted into a molecular signal. + GOC:ai + + + + + chemical nociception + GOC:pr + + + + + + + + + + + + + + + + + + + + The series of events involved in echolocation in which a mechanical stimulus is received and converted into a molecular signal. The stimulus is in the form of a reflected sound wave (an echo), which the organism uses to determine the distance to the object that reflected the sound wave. + echolocation, detection of mechanical stimulus + echolocation, sensory detection of mechanical stimulus + echolocation, sensory transduction of mechanical stimulus + sensory detection of mechanical stimulus during echolocation + sensory transduction of mechanical stimulus during echolocation + biological_process + GO:0050972 + detection of mechanical stimulus involved in echolocation + + + + + The series of events involved in echolocation in which a mechanical stimulus is received and converted into a molecular signal. The stimulus is in the form of a reflected sound wave (an echo), which the organism uses to determine the distance to the object that reflected the sound wave. + GOC:ai + GOC:dos + + + + + + + + + + + + + + + + + + + + The series of events involved in equilibrioception in which a mechanical stimulus is received and converted into a molecular signal. During equilibrioception, mechanical stimuli may be in the form of input from pressure receptors or from the labyrinth system of the inner ears. + equilibrioception, detection of mechanical stimulus + equilibrioception, sensory detection of mechanical stimulus + equilibrioception, sensory transduction of mechanical stimulus + sensory detection of mechanical stimulus during equilibrioception + sensory transduction of mechanical stimulus during equilibrioception + biological_process + GO:0050973 + detection of mechanical stimulus involved in equilibrioception + + + + + The series of events involved in equilibrioception in which a mechanical stimulus is received and converted into a molecular signal. During equilibrioception, mechanical stimuli may be in the form of input from pressure receptors or from the labyrinth system of the inner ears. + GOC:ai + GOC:dos + + + + + + + + + + + + + + + + + + + + + + + + + + + The series of events in which a mechanical stimulus is received and converted into a molecular signal as part of sensory perception. + sensory detection of mechanical stimulus + sensory detection of mechanical stimulus during sensory perception + sensory perception, sensory detection of mechanical stimulus + sensory perception, sensory transduction of mechanical stimulus + sensory transduction of mechanical stimulus + sensory transduction of mechanical stimulus during sensory perception + biological_process + GO:0050974 + detection of mechanical stimulus involved in sensory perception + + + + + The series of events in which a mechanical stimulus is received and converted into a molecular signal as part of sensory perception. + GOC:ai + GOC:dos + + + + + + + + + The series of events required for an organism to receive a touch stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. The perception of touch in animals is mediated by mechanoreceptors in the skin and mucous membranes and is the sense by which contact with objects gives evidence as to certain of their qualities. Different types of touch can be perceived (for example, light, coarse, pressure and tickling) and the stimulus may be external or internal (e.g. the feeling of a full stomach). + Wikipedia:Touch + perception of touch + tactile sense + taction + tactition + biological_process + GO:0050975 + sensory perception of touch + + + + + The series of events required for an organism to receive a touch stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. The perception of touch in animals is mediated by mechanoreceptors in the skin and mucous membranes and is the sense by which contact with objects gives evidence as to certain of their qualities. Different types of touch can be perceived (for example, light, coarse, pressure and tickling) and the stimulus may be external or internal (e.g. the feeling of a full stomach). + GOC:ai + + + + + + + + + + + + + + + + + + + + The series of events involved in the perception of touch in which a mechanical stimulus is received and converted into a molecular signal. + perception of touch, detection of mechanical stimulus + perception of touch, sensory detection of mechanical stimulus + perception of touch, sensory transduction of mechanical stimulus + sensory detection of mechanical stimulus during perception of touch + sensory transduction of mechanical stimulus during perception of touch + tactition, sensory detection of mechanical stimulus + biological_process + GO:0050976 + detection of mechanical stimulus involved in sensory perception of touch + + + + + The series of events involved in the perception of touch in which a mechanical stimulus is received and converted into a molecular signal. + GOC:ai + GOC:dos + + + + + + + + + + The series of events by which an electrical stimulus is received and converted into a molecular signal. + biological_process + GO:0050981 + detection of electrical stimulus + + + + + The series of events by which an electrical stimulus is received and converted into a molecular signal. + GOC:ai + GOC:dos + + + + + + + + + + + The series of events by which a mechanical stimulus is received and converted into a molecular signal. + biological_process + GO:0050982 + detection of mechanical stimulus + + + + + The series of events by which a mechanical stimulus is received and converted into a molecular signal. + GOC:ai + GOC:dos + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of lipids. + regulation of lipid breakdown + regulation of lipid catabolism + regulation of lipid degradation + biological_process + GO:0050994 + regulation of lipid catabolic process + + + + + Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of lipids. + GOC:ai + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids. + down regulation of lipid catabolic process + down-regulation of lipid catabolic process + downregulation of lipid catabolic process + negative regulation of lipid breakdown + negative regulation of lipid catabolism + negative regulation of lipid degradation + inhibition of lipid catabolic process + biological_process + GO:0050995 + negative regulation of lipid catabolic process + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids. + GOC:ai + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids. + positive regulation of lipid breakdown + positive regulation of lipid catabolism + positive regulation of lipid degradation + up regulation of lipid catabolic process + up-regulation of lipid catabolic process + upregulation of lipid catabolic process + activation of lipid catabolic process + stimulation of lipid catabolic process + biological_process + GO:0050996 + positive regulation of lipid catabolic process + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids. + GOC:ai + + + + + + + + + + + + + + + + + + + + The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness. + GO:0045011 + biological_process + actin bundling activity + actin cable assembly + actin cable formation + GO:0051017 + actin filament bundle assembly + + + + + The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness. + GOC:ai + + + + + actin cable assembly + GOC:mah + + + + + actin cable formation + GOC:mah + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or a tissue. + biological_process + GO:0051046 + regulation of secretion + + + + + Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or a tissue. + GOC:ai + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the controlled release of a substance from a cell or a tissue. + up regulation of secretion + up-regulation of secretion + upregulation of secretion + activation of secretion + stimulation of secretion + biological_process + GO:0051047 + positive regulation of secretion + + + + + Any process that activates or increases the frequency, rate or extent of the controlled release of a substance from a cell or a tissue. + GOC:ai + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a substance from a cell or a tissue. + down regulation of secretion + down-regulation of secretion + downregulation of secretion + inhibition of secretion + biological_process + GO:0051048 + negative regulation of secretion + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a substance from a cell or a tissue. + GOC:ai + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + biological_process + GO:0051049 + + regulation of transport + + + + + Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:ai + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + up regulation of transport + up-regulation of transport + upregulation of transport + activation of transport + stimulation of transport + biological_process + GO:0051050 + positive regulation of transport + + + + + Any process that activates or increases the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:ai + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + down regulation of transport + down-regulation of transport + downregulation of transport + inhibition of transport + biological_process + GO:0051051 + negative regulation of transport + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:ai + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids. + down regulation of lipid biosynthetic process + down-regulation of lipid biosynthetic process + downregulation of lipid biosynthetic process + negative regulation of lipid anabolism + negative regulation of lipid biosynthesis + negative regulation of lipid formation + negative regulation of lipid synthesis + negative regulation of lipogenesis + inhibition of lipid biosynthetic process + biological_process + GO:0051055 + negative regulation of lipid biosynthetic process + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids. + GOC:ai + + + + + negative regulation of lipogenesis + GOC:sl + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). + down regulation of developmental process + down-regulation of developmental process + downregulation of developmental process + inhibition of developmental process + biological_process + GO:0051093 + negative regulation of developmental process + + + + + Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). + GOC:ai + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). + up regulation of developmental process + up-regulation of developmental process + upregulation of developmental process + activation of developmental process + stimulation of developmental process + biological_process + GO:0051094 + positive regulation of developmental process + + + + + Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult). + GOC:ai + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule. + biological_process + GO:0051098 + regulation of binding + + + + + Any process that modulates the frequency, rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule. + GOC:ai + + + + + + + + + + + + + + + + + + + Any process that activates or increases the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule. + up regulation of binding + up-regulation of binding + upregulation of binding + activation of binding + stimulation of binding + biological_process + GO:0051099 + positive regulation of binding + + + + + Any process that activates or increases the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule. + GOC:ai + + + + + + + + + + + + + + + + + + + Any process that stops or reduces the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule. + down regulation of binding + down-regulation of binding + downregulation of binding + inhibition of binding + biological_process + GO:0051100 + negative regulation of binding + + + + + Any process that stops or reduces the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule. + GOC:ai + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. + regulation of cellular component organisation + biological_process + regulation of cell organisation + regulation of cell organization + regulation of cellular component organization and biogenesis + GO:0051128 + regulation of cellular component organization + + + + + Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. + GOC:ai + + + + + regulation of cell organisation + GOC:mah + + + + + regulation of cell organization + GOC:mah + + + + + regulation of cellular component organization and biogenesis + GOC:mah + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. + down regulation of cell organization + down-regulation of cell organization + downregulation of cell organization + inhibition of cell organization + biological_process + negative regulation of cell organisation + negative regulation of cellular component organization and biogenesis + GO:0051129 + negative regulation of cellular component organization + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. + GOC:ai + + + + + negative regulation of cell organisation + GOC:mah + + + + + negative regulation of cellular component organization and biogenesis + GOC:mah + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. + positive regulation of cell organisation + up regulation of cell organization + up-regulation of cell organization + upregulation of cell organization + activation of cell organization + stimulation of cell organization + biological_process + positive regulation of cellular component organization and biogenesis + GO:0051130 + positive regulation of cellular component organization + + + + + Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope. + GOC:ai + + + + + positive regulation of cellular component organization and biogenesis + GOC:mah + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary. + nonstriated muscle cell differentiation + biological_process + GO:0051145 + smooth muscle cell differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary. + CL:0000192 + GOC:ai + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of a striated muscle cell; striated muscle fibers are divided by transverse bands into striations, and cardiac and voluntary muscle are types of striated muscle. + voluntary muscle cell differentiation + biological_process + GO:0051146 + striated muscle cell differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized features of a striated muscle cell; striated muscle fibers are divided by transverse bands into striations, and cardiac and voluntary muscle are types of striated muscle. + CL:0000737 + GOC:ai + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of muscle cell differentiation. + biological_process + GO:0051147 + regulation of muscle cell differentiation + + + + + Any process that modulates the frequency, rate or extent of muscle cell differentiation. + CL:0000187 + GOC:ai + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of muscle cell differentiation. + down regulation of muscle cell differentiation + down-regulation of muscle cell differentiation + downregulation of muscle cell differentiation + inhibition of muscle cell differentiation + biological_process + GO:0051148 + negative regulation of muscle cell differentiation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of muscle cell differentiation. + CL:0000187 + GOC:ai + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of muscle cell differentiation. + up regulation of muscle cell differentiation + up-regulation of muscle cell differentiation + upregulation of muscle cell differentiation + activation of muscle cell differentiation + stimulation of muscle cell differentiation + biological_process + GO:0051149 + positive regulation of muscle cell differentiation + + + + + Any process that activates or increases the frequency, rate or extent of muscle cell differentiation. + CL:0000187 + GOC:ai + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of smooth muscle cell differentiation. + biological_process + GO:0051150 + regulation of smooth muscle cell differentiation + + + + + Any process that modulates the frequency, rate or extent of smooth muscle cell differentiation. + CL:0000192 + GOC:ai + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell differentiation. + down regulation of smooth muscle cell differentiation + down-regulation of smooth muscle cell differentiation + downregulation of smooth muscle cell differentiation + inhibition of smooth muscle cell differentiation + biological_process + GO:0051151 + negative regulation of smooth muscle cell differentiation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell differentiation. + CL:0000192 + GOC:ai + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of smooth muscle cell differentiation. + up regulation of smooth muscle cell differentiation + up-regulation of smooth muscle cell differentiation + upregulation of smooth muscle cell differentiation + activation of smooth muscle cell differentiation + stimulation of smooth muscle cell differentiation + biological_process + GO:0051152 + positive regulation of smooth muscle cell differentiation + + + + + Any process that activates or increases the frequency, rate or extent of smooth muscle cell differentiation. + CL:0000192 + GOC:ai + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of striated muscle cell differentiation. + biological_process + GO:0051153 + regulation of striated muscle cell differentiation + + + + + Any process that modulates the frequency, rate or extent of striated muscle cell differentiation. + CL:0000737 + GOC:ai + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle cell differentiation. + down regulation of striated muscle cell differentiation + down-regulation of striated muscle cell differentiation + downregulation of striated muscle cell differentiation + inhibition of striated muscle cell differentiation + biological_process + GO:0051154 + negative regulation of striated muscle cell differentiation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle cell differentiation. + CL:0000737 + GOC:ai + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of striated muscle cell differentiation. + up regulation of striated muscle cell differentiation + up-regulation of striated muscle cell differentiation + upregulation of striated muscle cell differentiation + activation of striated muscle cell differentiation + stimulation of striated muscle cell differentiation + biological_process + GO:0051155 + positive regulation of striated muscle cell differentiation + + + + + Any process that activates or increases the frequency, rate or extent of striated muscle cell differentiation. + CL:0000737 + GOC:ai + + + + + + + + + + + + + + + + + + + + + + + The directed movement of substances into, out of, or within the nucleus. + Wikipedia:Nuclear_transport + nucleus transport + biological_process + GO:0051169 + + nuclear transport + + + + + The directed movement of substances into, out of, or within the nucleus. + GOC:ai + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds. + regulation of nitrogen metabolic process + regulation of nitrogen metabolism + biological_process + GO:0051171 + regulation of nitrogen compound metabolic process + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds. + GOC:ai + GOC:tb + + + + + regulation of nitrogen metabolic process + GOC:tb + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds. + down regulation of nitrogen metabolic process + down-regulation of nitrogen metabolic process + downregulation of nitrogen metabolic process + negative regulation of nitrogen metabolic process + negative regulation of nitrogen metabolism + inhibition of nitrogen metabolic process + biological_process + GO:0051172 + negative regulation of nitrogen compound metabolic process + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds. + GOC:ai + GOC:tb + + + + + negative regulation of nitrogen metabolic process + GOC:tb + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds. + positive regulation of nitrogen metabolic process + positive regulation of nitrogen metabolism + up regulation of nitrogen metabolic process + up-regulation of nitrogen metabolic process + upregulation of nitrogen metabolic process + activation of nitrogen metabolic process + stimulation of nitrogen metabolic process + biological_process + GO:0051173 + positive regulation of nitrogen compound metabolic process + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds. + GOC:ai + GOC:tb + + + + + positive regulation of nitrogen metabolic process + GOC:tb + + + + + + + + + Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation. + jl + 2013-12-18T13:51:04Z + GO:1902578 + establishment and maintenance of localization + establishment and maintenance of position + localisation + establishment and maintenance of cellular component location + establishment and maintenance of substance location + establishment and maintenance of substrate location + biological_process + single organism localization + single-organism localization + GO:0051179 + + localization + + + + + Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation. + GOC:ai + GOC:dos + + + + + localisation + GOC:mah + + + + + single organism localization + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. + Wikipedia:Chondrogenesis + cartilage biogenesis + cartilage biosynthesis + cartilage element development + cartilage formation + cartilage organ development + chondrogenesis + biological_process + GO:0051216 + cartilage development + + + + + The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. + GOC:cjm + PMID:23251424 + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + up regulation of protein transport + up-regulation of protein transport + upregulation of protein transport + activation of protein transport + stimulation of protein transport + biological_process + GO:0051222 + positive regulation of protein transport + + + + + Any process that activates or increases the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:ai + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + biological_process + GO:0051223 + regulation of protein transport + + + + + Any process that modulates the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:ai + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + down regulation of protein transport + down-regulation of protein transport + downregulation of protein transport + inhibition of protein transport + biological_process + GO:0051224 + negative regulation of protein transport + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:ai + + + + + + + + + Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation. + establishment of localisation + biological_process + GO:0051234 + + + + + establishment of localization + + + + + Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation. + GOC:ai + GOC:dos + + + + + establishment of localisation + GOC:mah + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs. + biological_process + GO:0051239 + regulation of multicellular organismal process + + + + + Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs. + GOC:ai + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs. + up regulation of multicellular organismal process + up-regulation of multicellular organismal process + upregulation of multicellular organismal process + activation of multicellular organismal process + stimulation of multicellular organismal process + biological_process + GO:0051240 + positive regulation of multicellular organismal process + + + + + Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs. + GOC:ai + + + + + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs. + down regulation of multicellular organismal process + down-regulation of multicellular organismal process + downregulation of multicellular organismal process + inhibition of multicellular organismal process + biological_process + GO:0051241 + negative regulation of multicellular organismal process + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs. + GOC:ai + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein. + regulation of protein metabolism + biological_process + GO:0051246 + regulation of protein metabolic process + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein. + GOC:ai + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein. + https://github.com/geneontology/go-ontology/issues/23112 + GO:0032270 + positive regulation of cellular protein metabolic process + positive regulation of cellular protein metabolism + positive regulation of protein metabolism + up regulation of cellular protein metabolic process + up regulation of protein metabolic process + up-regulation of cellular protein metabolic process + up-regulation of protein metabolic process + upregulation of cellular protein metabolic process + upregulation of protein metabolic process + activation of cellular protein metabolic process + activation of protein metabolic process + stimulation of cellular protein metabolic process + stimulation of protein metabolic process + biological_process + GO:0051247 + positive regulation of protein metabolic process + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein. + GOC:ai + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein. + https://github.com/geneontology/go-ontology/issues/23112 + GO:0032269 + down regulation of cellular protein metabolic process + down regulation of protein metabolic process + down-regulation of cellular protein metabolic process + down-regulation of protein metabolic process + downregulation of cellular protein metabolic process + downregulation of protein metabolic process + negative regulation of cellular protein metabolic process + negative regulation of cellular protein metabolism + negative regulation of protein metabolism + inhibition of cellular protein metabolic process + inhibition of protein metabolic process + biological_process + GO:0051248 + negative regulation of protein metabolic process + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein. + GOC:ai + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of lymphocyte activation. + biological_process + GO:0051249 + regulation of lymphocyte activation + + + + + Any process that modulates the frequency, rate or extent of lymphocyte activation. + GOC:ai + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte activation. + down regulation of lymphocyte activation + down-regulation of lymphocyte activation + downregulation of lymphocyte activation + inhibition of lymphocyte activation + biological_process + GO:0051250 + negative regulation of lymphocyte activation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte activation. + GOC:ai + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of lymphocyte activation. + up regulation of lymphocyte activation + up-regulation of lymphocyte activation + upregulation of lymphocyte activation + activation of lymphocyte activation + stimulation of lymphocyte activation + biological_process + GO:0051251 + positive regulation of lymphocyte activation + + + + + Any process that activates or increases the frequency, rate or extent of lymphocyte activation. + GOC:ai + + + + + + + + + The process of creating protein polymers, compounds composed of a large number of component monomers; polymeric proteins may be made up of different or identical monomers. Polymerization occurs by the addition of extra monomers to an existing poly- or oligomeric protein. + protein polymer biosynthesis + protein polymer biosynthetic process + protein polymer formation + biological_process + GO:0051258 + + protein polymerization + + + + + The process of creating protein polymers, compounds composed of a large number of component monomers; polymeric proteins may be made up of different or identical monomers. Polymerization occurs by the addition of extra monomers to an existing poly- or oligomeric protein. + GOC:ai + + + + + + + + + The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells. + Wikipedia:Cell_division + biological_process + GO:0051301 + + + + Note that this term differs from 'cytokinesis ; GO:0000910' in that cytokinesis does not include nuclear division. + cell division + + + + + The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells. + GOC:di + GOC:go_curators + GOC:pr + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells. + biological_process + GO:0051302 + regulation of cell division + + + + + Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells. + GOC:go_curators + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions. + GO:0007126 + Wikipedia:Meiosis + biological_process + meiosis + GO:0051321 + + + Note that this term should not be confused with 'GO:0140013 ; meiotic nuclear division'. 'GO:0051321 ; meiotic cell cycle represents the entire mitotic cell cycle, while 'GO:0140013 meiotic nuclear division' specifically represents the actual nuclear division step of the mitotic cell cycle. + meiotic cell cycle + + + + + Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions. + GOC:ai + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. + transferase regulator + biological_process + GO:0051338 + + This term is useful for grouping, but is too general for manual annotation. Please use a child term instead. + regulation of transferase activity + + + + + Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2. + GOC:ai + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor. + transferase activator + up regulation of transferase activity + up-regulation of transferase activity + upregulation of transferase activity + activation of transferase activity + stimulation of transferase activity + biological_process + GO:0051347 + + This term is useful for grouping, but is too general for manual annotation. Please use a child term instead. + positive regulation of transferase activity + + + + + Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor. + GOC:ai + + + + + + + + + + + + + + + + + + + Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor. + down regulation of transferase activity + down-regulation of transferase activity + downregulation of transferase activity + transferase inhibitor + inhibition of transferase activity + biological_process + GO:0051348 + + This term is useful for grouping, but is too general for manual annotation. Please use a child term instead. + negative regulation of transferase activity + + + + + Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor. + GOC:ai + + + + + + + + + + + + + + + + + + + + The series of events contributing to equilibrioception by which an organism senses the position, location, orientation, and movement of the body and its parts. Proprioception plays an important role in the ability of an organism to perceive its orientation with respect to gravity. + equilibrioception by proprioception + perception of orientation with respect to gravity by proprioception + biological_process + proprioception during equilibrioception + GO:0051355 + proprioception involved in equilibrioception + + + + + The series of events contributing to equilibrioception by which an organism senses the position, location, orientation, and movement of the body and its parts. Proprioception plays an important role in the ability of an organism to perceive its orientation with respect to gravity. + GOC:ai + + + + + proprioception during equilibrioception + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + The series of events during equilibrioception required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual input plays an important role in the ability of an organism to perceive its orientation with respect to gravity. + perception of orientation with respect to gravity by visual perception + equilibrioception by visual perception + biological_process + visual perception during equilibrioception + GO:0051356 + visual perception involved in equilibrioception + + + + + The series of events during equilibrioception required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual input plays an important role in the ability of an organism to perceive its orientation with respect to gravity. + GOC:ai + + + + + visual perception during equilibrioception + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + Binding to serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties. + 5-hydroxytryptamine binding + molecular_function + GO:0051378 + serotonin binding + + + + + Binding to serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties. + GOC:ai + + + + + + + + + + + + + + + + + + + Binding to norepinephrine, (3,4-dihydroxyphenyl-2-aminoethanol), a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine. + noradrenaline binding + molecular_function + GO:0051380 + norepinephrine binding + + + + + Binding to norepinephrine, (3,4-dihydroxyphenyl-2-aminoethanol), a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine. + GOC:ai + + + + + + + + + + + + + + + + + + + Binding to histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans. + molecular_function + GO:0051381 + histamine binding + + + + + Binding to histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans. + GOC:ai + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects. + response to glucocorticoid stimulus + biological_process + GO:0051384 + response to glucocorticoid + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects. + GOC:ai + PMID:9884123 + + + + + response to glucocorticoid stimulus + GOC:dos + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mineralocorticoid stimulus. Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. Mineralocorticoids act primarily on water and electrolyte balance. + response to mineralocorticoid stimulus + biological_process + GO:0051385 + response to mineralocorticoid + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mineralocorticoid stimulus. Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. Mineralocorticoids act primarily on water and electrolyte balance. + GOC:ai + PMID:9884123 + + + + + response to mineralocorticoid stimulus + GOC:dos + + + + + + + + + + + + + + + + + + + + + Any process that modulates the rate or extent of progression through the meiotic cell cycle. + meiotic cell cycle modulation + meiotic cell cycle regulation + modulation of meiotic cell cycle progression + regulation of meiotic cell cycle progression + regulation of progression through meiotic cell cycle + biological_process + meiotic cell cycle regulator + GO:0051445 + regulation of meiotic cell cycle + + + + + Any process that modulates the rate or extent of progression through the meiotic cell cycle. + GOC:ai + GOC:dph + GOC:tb + + + + + regulation of progression through meiotic cell cycle + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of progression through the meiotic cell cycle. + positive regulation of meiotic cell cycle progression + positive regulation of progression through meiotic cell cycle + up regulation of progression through meiotic cell cycle + up-regulation of progression through meiotic cell cycle + upregulation of progression through meiotic cell cycle + activation of progression through meiotic cell cycle + stimulation of progression through meiotic cell cycle + biological_process + GO:0051446 + positive regulation of meiotic cell cycle + + + + + Any process that activates or increases the frequency, rate or extent of progression through the meiotic cell cycle. + GOC:ai + GOC:dph + GOC:tb + + + + + positive regulation of progression through meiotic cell cycle + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the rate or extent of progression through the meiotic cell cycle. + down regulation of progression through meiotic cell cycle + down-regulation of progression through meiotic cell cycle + downregulation of progression through meiotic cell cycle + negative regulation of meiotic cell cycle progression + negative regulation of progression through meiotic cell cycle + inhibition of progression through meiotic cell cycle + biological_process + GO:0051447 + negative regulation of meiotic cell cycle + + + + + Any process that stops, prevents or reduces the rate or extent of progression through the meiotic cell cycle. + GOC:ai + GOC:dph + GOC:tb + + + + + negative regulation of progression through meiotic cell cycle + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + + + + + + The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the vacuole. + GO:0042146 + biological_process + heterotypic vacuole fusion (non-autophagic) + heterotypic vacuole fusion, non-autophagic + GO:0051469 + vesicle fusion with vacuole + + + + + The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the vacuole. + GOC:ai + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures. + regulation of cytoskeleton organisation + biological_process + regulation of cytoskeleton organization and biogenesis + GO:0051493 + regulation of cytoskeleton organization + + + + + Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures. + GOC:ai + + + + + regulation of cytoskeleton organisation + GOC:mah + + + + + regulation of cytoskeleton organization and biogenesis + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures. + down regulation of cytoskeleton organization + down-regulation of cytoskeleton organization + downregulation of cytoskeleton organization + negative regulation of cytoskeleton organisation + inhibition of cytoskeleton organization + biological_process + negative regulation of cytoskeleton organization and biogenesis + GO:0051494 + negative regulation of cytoskeleton organization + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures. + GOC:ai + + + + + negative regulation of cytoskeleton organisation + GOC:mah + + + + + negative regulation of cytoskeleton organization and biogenesis + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures. + positive regulation of cytoskeleton organisation + up regulation of cytoskeleton organization + up-regulation of cytoskeleton organization + upregulation of cytoskeleton organization + activation of cytoskeleton organization + stimulation of cytoskeleton organization + biological_process + positive regulation of cytoskeleton organization and biogenesis + GO:0051495 + positive regulation of cytoskeleton organization + + + + + Any process that activates or increases the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures. + GOC:ai + + + + + positive regulation of cytoskeleton organisation + GOC:mah + + + + + positive regulation of cytoskeleton organization and biogenesis + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The directed movement of a keratinocyte, epidermal cells which synthesize keratin, from one site to another. + + biological_process + GO:0051546 + keratinocyte migration + + + + + The directed movement of a keratinocyte, epidermal cells which synthesize keratin, from one site to another. + ISBN:0721662544 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of keratinocyte migration. + biological_process + GO:0051547 + regulation of keratinocyte migration + + + + + Any process that modulates the frequency, rate or extent of keratinocyte migration. + GOC:ai + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of keratinocyte migration. + down regulation of keratinocyte migration + down-regulation of keratinocyte migration + downregulation of keratinocyte migration + inhibition of keratinocyte migration + biological_process + GO:0051548 + negative regulation of keratinocyte migration + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of keratinocyte migration. + GOC:ai + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of keratinocyte migration. + up regulation of keratinocyte migration + up-regulation of keratinocyte migration + upregulation of keratinocyte migration + activation of keratinocyte migration + stimulation of keratinocyte migration + biological_process + GO:0051549 + positive regulation of keratinocyte migration + + + + + Any process that activates or increases the frequency, rate or extent of keratinocyte migration. + GOC:ai + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + biological_process + GO:0051588 + regulation of neurotransmitter transport + + + + + Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:ai + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + down regulation of neurotransmitter transport + down-regulation of neurotransmitter transport + downregulation of neurotransmitter transport + inhibition of neurotransmitter transport + biological_process + GO:0051589 + negative regulation of neurotransmitter transport + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:ai + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + up regulation of neurotransmitter transport + up-regulation of neurotransmitter transport + upregulation of neurotransmitter transport + activation of neurotransmitter transport + stimulation of neurotransmitter transport + biological_process + GO:0051590 + positive regulation of neurotransmitter transport + + + + + Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:ai + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus. + response to Ca2+ ion + biological_process + GO:0051592 + response to calcium ion + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus. + GOC:ai + + + + + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus. + biological_process + response to electricity + GO:0051602 + response to electrical stimulus + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus. + GOC:ai + + + + + + + + + The series of events in which a stimulus is received by a cell or organism and converted into a molecular signal. + stimulus detection + biological_process + perception of stimulus + stimulus sensing + GO:0051606 + + detection of stimulus + + + + + The series of events in which a stimulus is received by a cell or organism and converted into a molecular signal. + GOC:add + GOC:ai + GOC:dph + GOC:mah + + + + + + + + + + + + + + + + + + + The directed movement of histamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans. + biological_process + GO:0051608 + histamine transport + + + + + The directed movement of histamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans. + GOC:ai + + + + + + + + + + + + + + + + + + + + + + + + + + + The directed movement of norepinephrine into a cell, typically presynaptic neurons or glial cells. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine. + levarterenol reuptake + levarterenol uptake + noradrenaline reuptake + noradrenaline uptake + norepinephrine import + norepinephrine reuptake + biological_process + GO:0051620 + norepinephrine uptake + + + + + The directed movement of norepinephrine into a cell, typically presynaptic neurons or glial cells. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine. + GOC:ai + + + + + norepinephrine import + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter norepinephrine into a cell. + regulation of levarterenol uptake + regulation of noradrenaline uptake + regulation of norepinephrine import + biological_process + GO:0051621 + regulation of norepinephrine uptake + + + + + Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter norepinephrine into a cell. + GOC:ai + + + + + regulation of norepinephrine import + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of norepinephrine into a cell. + down regulation of norepinephrine uptake + down-regulation of norepinephrine uptake + downregulation of norepinephrine uptake + negative regulation of levarterenol uptake + negative regulation of noradrenaline uptake + negative regulation of norepinephrine import + biological_process + GO:0051622 + negative regulation of norepinephrine uptake + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of norepinephrine into a cell. + GOC:ai + + + + + negative regulation of norepinephrine import + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the directed movement of norepinephrine into a cell. + positive regulation of levarterenol uptake + positive regulation of noradrenaline uptake + positive regulation of norepinephrine import + up regulation of norepinephrine uptake + up-regulation of norepinephrine uptake + upregulation of norepinephrine uptake + activation of norepinephrine uptake + stimulation of norepinephrine uptake + biological_process + GO:0051623 + positive regulation of norepinephrine uptake + + + + + Any process that activates or increases the frequency, rate or extent of the directed movement of norepinephrine into a cell. + GOC:ai + + + + + positive regulation of norepinephrine import + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Any process in which an organelle is transported to, and/or maintained in, a specific location. + https://github.com/geneontology/go-ontology/issues/19809 + establishment and maintenance of organelle localization + organelle localisation + biological_process + GO:0051640 + + organelle localization + + + + + Any process in which an organelle is transported to, and/or maintained in, a specific location. + GOC:ai + + + + + organelle localisation + GOC:mah + + + + + + + + + + A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane. + jl + 2013-12-18T14:04:32Z + GO:1902580 + cellular localisation + establishment and maintenance of cellular localization + establishment and maintenance of localization in cell or cell membrane + single organism cellular localization + intracellular localization + localization within cell + biological_process + single-organism cellular localization + GO:0051641 + + cellular localization + + + + + A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane. + GOC:tb + GOC:vw + + + + + cellular localisation + GOC:mah + + + + + single organism cellular localization + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process in which the Golgi is transported to, and/or maintained in, a specific location within the cell. + Golgi apparatus localization + Golgi body localization + Golgi localisation + establishment and maintenance of Golgi localization + biological_process + GO:0051645 + Golgi localization + + + + + Any process in which the Golgi is transported to, and/or maintained in, a specific location within the cell. + GOC:ai + + + + + Golgi localisation + GOC:mah + + + + + + + + + + + + + + + + + + + Any process in which the nucleus is transported to, and/or maintained in, a specific location within the cell. + cell nucleus localization + establishment and maintenance of nucleus localization + localization of nucleus + nucleus localisation + biological_process + GO:0051647 + nucleus localization + + + + + Any process in which the nucleus is transported to, and/or maintained in, a specific location within the cell. + GOC:ai + + + + + nucleus localisation + GOC:mah + + + + + + + + + + + + + + + + + + + Any process in which a vesicle or vesicles are transported to, and/or maintained in, a specific location. + cytoplasmic vesicle localization + establishment and maintenance of vesicle localization + vesicle localisation + biological_process + GO:0051648 + vesicle localization + + + + + Any process in which a vesicle or vesicles are transported to, and/or maintained in, a specific location. + GOC:ai + + + + + vesicle localisation + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Any process, occuring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation. + establishment of localisation in cell + establishment of intracellular localization + establishment of localization within cell + positioning within cell + biological_process + establishment of cellular localization + GO:0051649 + establishment of localization in cell + + + + + Any process, occuring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation. + GOC:ai + GOC:dos + GOC:dph + GOC:tb + + + + + establishment of localisation in cell + GOC:mah + + + + + establishment of cellular localization + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + + The directed movement of a vesicle to a specific location. + establishment of vesicle localisation + biological_process + GO:0051650 + establishment of vesicle localization + + + + + The directed movement of a vesicle to a specific location. + GOC:ai + + + + + establishment of vesicle localisation + GOC:mah + + + + + + + + + + + + + + + + + + + + The directed movement of an organelle to a specific location. + establishment of organelle localisation + biological_process + GO:0051656 + establishment of organelle localization + + + + + The directed movement of an organelle to a specific location. + GOC:ai + + + + + establishment of organelle localisation + GOC:mah + + + + + + + + + + + + + + + + + + + + Any process in which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a membrane. + establishment and maintenance of localization in membrane + establishment and maintenance of position in membrane + localisation within membrane + localization to membrane + positioning within membrane + biological_process + GO:0051668 + localization within membrane + + + + + Any process in which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a membrane. + GOC:ai + + + + + localisation within membrane + GOC:mah + + + + + + + + + + + + + + + + + + + + Any process in which a cell is transported to, and/or maintained in, a specific location. + cell localization + establishment and maintenance of cell localization + establishment and maintenance of localization of cell + localisation of cell + biological_process + GO:0051674 + localization of cell + + + + + Any process in which a cell is transported to, and/or maintained in, a specific location. + GOC:ai + + + + + localisation of cell + GOC:mah + + + + + + + + + + + + + + + + + + + + + The directed movement of the Golgi to a specific location. + establishment of Golgi apparatus localization + establishment of Golgi body localization + establishment of Golgi localisation + biological_process + GO:0051683 + establishment of Golgi localization + + + + + The directed movement of the Golgi to a specific location. + GOC:ai + + + + + establishment of Golgi localisation + GOC:mah + + + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism. + GO:0009613 + GO:0042828 + biological_process + GO:0051707 + response to other organism + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism. + GOC:ai + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell. + biological_process + GO:0051716 + + Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. + cellular response to stimulus + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell. + GOC:bf + GOC:jl + + + + + + + + + + + + + + + + + + + Any process that modulates the rate or extent of progression through the cell cycle. + GO:0000074 + GO:0007050 + GO:0071156 + GO:0071157 + GO:0071158 + GO:0071850 + cell cycle modulation + cell cycle regulation + control of cell cycle progression + modulation of cell cycle progression + regulation of cell cycle progression + regulation of progression through cell cycle + arrest of mitotic cell cycle progression + cell cycle arrest + mitotic cell cycle arrest + negative regulation of cell cycle arrest + positive regulation of cell cycle arrest + regulation of cell cycle arrest + biological_process + cell cycle regulator + tumor suppressor + GO:0051726 + + regulation of cell cycle + + + + + Any process that modulates the rate or extent of progression through the cell cycle. + GOC:ai + GOC:dph + GOC:tb + + + + + arrest of mitotic cell cycle progression + GOC:mah + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of cell division. + up regulation of cell division + up-regulation of cell division + upregulation of cell division + activation of cell division + stimulation of cell division + biological_process + GO:0051781 + positive regulation of cell division + + + + + Any process that activates or increases the frequency, rate or extent of cell division. + GOC:ai + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of cell division. + down regulation of cell division + down-regulation of cell division + downregulation of cell division + inhibition of cell division + biological_process + GO:0051782 + negative regulation of cell division + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of cell division. + GOC:ai + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information. + biological_process + GO:0051783 + regulation of nuclear division + + + + + Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information. + GOC:ai + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information. + down regulation of nuclear division + down-regulation of nuclear division + downregulation of nuclear division + inhibition of nuclear division + biological_process + GO:0051784 + negative regulation of nuclear division + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information. + GOC:ai + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information. + up regulation of nuclear division + up-regulation of nuclear division + upregulation of nuclear division + activation of nuclear division + stimulation of nuclear division + biological_process + GO:0051785 + positive regulation of nuclear division + + + + + Any process that activates or increases the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information. + GOC:ai + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of hair follicle development. + biological_process + GO:0051797 + regulation of hair follicle development + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate or extent of hair follicle development. + GOC:ai + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of hair follicle development. + up regulation of hair follicle development + up-regulation of hair follicle development + upregulation of hair follicle development + activation of hair follicle development + stimulation of hair follicle development + biological_process + GO:0051798 + positive regulation of hair follicle development + + + + + Any process that activates or increases the frequency, rate or extent of hair follicle development. + GOC:ai + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of hair follicle development. + down regulation of hair follicle development + down-regulation of hair follicle development + downregulation of hair follicle development + inhibition of hair follicle development + biological_process + GO:0051799 + negative regulation of hair follicle development + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of hair follicle development. + GOC:ai + + + + + + + + + + + + + + + + + + + + + + + + + Any process in which a pigment granule is transported to, and/or maintained in, a specific location within the cell. + pigment granule localisation + biological_process + GO:0051875 + pigment granule localization + + + + + Any process in which a pigment granule is transported to, and/or maintained in, a specific location within the cell. + GOC:ai + + + + + pigment granule localisation + GOC:mah + + + + + + + + + + + + + + + + + + + + + The directed movement of pigment granules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + pigment granule translocation + biological_process + GO:0051904 + pigment granule transport + + + + + The directed movement of pigment granules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:ai + + + + + + + + + + + + + + + The directed movement of a pigment granule to a specific location. + establishment of pigment granule localisation + biological_process + GO:0051905 + establishment of pigment granule localization + + + + + The directed movement of a pigment granule to a specific location. + GOC:ai + + + + + establishment of pigment granule localisation + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + regulation of calcium transport + biological_process + GO:0051924 + regulation of calcium ion transport + + + + + Any process that modulates the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:ai + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + down regulation of calcium ion transport + down-regulation of calcium ion transport + downregulation of calcium ion transport + negative regulation of calcium transport + inhibition of calcium ion transport + biological_process + GO:0051926 + negative regulation of calcium ion transport + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:ai + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + positive regulation of calcium transport + up regulation of calcium ion transport + up-regulation of calcium ion transport + upregulation of calcium ion transport + activation of calcium ion transport + stimulation of calcium ion transport + biological_process + GO:0051928 + positive regulation of calcium ion transport + + + + + Any process that activates or increases the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:ai + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. + biological_process + GO:0051930 + regulation of sensory perception of pain + + + + + Any process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. + GOC:ai + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of sensory perception, the series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. + biological_process + GO:0051931 + regulation of sensory perception + + + + + Any process that modulates the frequency, rate or extent of sensory perception, the series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. + GOC:ai + + + + + + + + + + + + + + + + + + + The directed movement of catecholamines, a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. + biological_process + GO:0051937 + catecholamine transport + + + + + The directed movement of catecholamines, a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine. + GOC:ai + ISBN:0198506732 + + + + + + + + + + + + + + + + + + + The directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a cell or organelle. + 4-aminobutyrate import + GABA import + gamma-aminobutyrate import + gamma-aminobutyric acid uptake + biological_process + GO:0051939 + gamma-aminobutyric acid import + + + + + The directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a cell or organelle. + GOC:ai + + + + + gamma-aminobutyric acid uptake + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + biological_process + GO:0051952 + regulation of amine transport + + + + + Any process that modulates the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:ai + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + down regulation of amine transport + down-regulation of amine transport + downregulation of amine transport + inhibition of amine transport + biological_process + GO:0051953 + negative regulation of amine transport + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:ai + + + + + + + + + + + + + + + + + + + + + Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + up regulation of amine transport + up-regulation of amine transport + upregulation of amine transport + activation of amine transport + stimulation of amine transport + biological_process + GO:0051954 + positive regulation of amine transport + + + + + Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:ai + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + biological_process + GO:0051955 + regulation of amino acid transport + + + + + Any process that modulates the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:ai + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + down regulation of amino acid transport + down-regulation of amino acid transport + downregulation of amino acid transport + negative regulation of amino acid transmembrane transport + inhibition of amino acid transport + biological_process + GO:0051956 + negative regulation of amino acid transport + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:ai + + + + + negative regulation of amino acid transmembrane transport + GOC:mah + + + + + + + + + + + + + + + + + + + + Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + positive regulation of amino acid transmembrane transport + up regulation of amino acid transport + up-regulation of amino acid transport + upregulation of amino acid transport + activation of amino acid transport + stimulation of amino acid transport + biological_process + GO:0051957 + positive regulation of amino acid transport + + + + + Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:ai + + + + + positive regulation of amino acid transmembrane transport + GOC:mah + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue. + biological_process + GO:0051960 + regulation of nervous system development + + + + + Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue. + GOC:ai + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue. + down regulation of nervous system development + down-regulation of nervous system development + downregulation of nervous system development + inhibition of nervous system development + biological_process + GO:0051961 + negative regulation of nervous system development + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue. + GOC:ai + + + + + + + + + + + + + + + + + + + + + + Any process that activates, maintains or increases the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue. + up regulation of nervous system development + up-regulation of nervous system development + upregulation of nervous system development + activation of nervous system development + stimulation of nervous system development + biological_process + GO:0051962 + positive regulation of nervous system development + + + + + Any process that activates, maintains or increases the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue. + GOC:ai + + + + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways involving imidazoles, five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton. + imidazole metabolism + biological_process + GO:0052803 + imidazole-containing compound metabolic process + + + + + The chemical reactions and pathways involving imidazoles, five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton. + GOC:curators + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of imidazoles, five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton. + imidazole breakdown + imidazole catabolism + imidazole degradation + biological_process + GO:0052805 + imidazole-containing compound catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of imidazoles, five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton. + GOC:curators + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a muscle cell over time, from its formation to the mature structure. Muscle cell development does not include the steps involved in committing an unspecified cell to the muscle cell fate. + GO:0048747 + muscle fiber development + muscle fibre development + myofiber development + myofibre development + biological_process + GO:0055001 + muscle cell development + + + + + The process whose specific outcome is the progression of a muscle cell over time, from its formation to the mature structure. Muscle cell development does not include the steps involved in committing an unspecified cell to the muscle cell fate. + CL:0000187 + GOC:devbiol + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a striated muscle cell over time, from its formation to the mature structure. Striated muscle cells contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. + biological_process + GO:0055002 + striated muscle cell development + + + + + The process whose specific outcome is the progression of a striated muscle cell over time, from its formation to the mature structure. Striated muscle cells contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. + CL:0000737 + GOC:devbiol + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells. + cardiac myofibril development + cardiac myofibril morphogenesis + biological_process + heart myofibril assembly + GO:0055003 + cardiac myofibril assembly + + + + + The process whose specific outcome is the progression of the cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells. + GOC:devbiol + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a cardiac cell over time, from its formation to the mature state. A cardiac cell is a cell that will form part of the cardiac organ of an individual. + cardiocyte development + biological_process + heart cell development + GO:0055006 + cardiac cell development + + + + + The process whose specific outcome is the progression of a cardiac cell over time, from its formation to the mature state. A cardiac cell is a cell that will form part of the cardiac organ of an individual. + GOC:devbiol + + + + + cardiocyte development + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a cardiac muscle precursor cell acquires specialized features of a cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. + cardiomyocyte differentiation + biological_process + heart muscle cell differentiation + GO:0055007 + cardiac muscle cell differentiation + + + + + The process in which a cardiac muscle precursor cell acquires specialized features of a cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. + GOC:devbiol + GOC:mtg_heart + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of cardiac muscle tissue are generated and organized. + myocardium morphogenesis + heart muscle morphogenesis + biological_process + GO:0055008 + cardiac muscle tissue morphogenesis + + + + + The process in which the anatomical structures of cardiac muscle tissue are generated and organized. + GOC:devbiol + + + + + myocardium morphogenesis + GOC:mtg_heart + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of cardiac atrium muscle is generated and organized. + atrial heart muscle morphogenesis + atrial myocardium morphogenesis + cardiac atrium muscle morphogenesis + biological_process + GO:0055009 + atrial cardiac muscle tissue morphogenesis + + + + + The process in which the anatomical structure of cardiac atrium muscle is generated and organized. + GOC:devbiol + + + + + atrial myocardium morphogenesis + GOC:mtg_heart + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of cardiac ventricle muscle is generated and organized. + cardiac ventricle muscle morphogenesis + ventricular heart muscle morphogenesis + biological_process + GO:0055010 + ventricular cardiac muscle tissue morphogenesis + + + + + The process in which the anatomical structures of cardiac ventricle muscle is generated and organized. + GOC:devbiol + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a cardiac muscle cell over time, from its formation to the mature state. + GO:0048739 + cardiac muscle fiber development + cardiac muscle fibre development + cardiomyocyte cell development + heart muscle cell development + biological_process + heart muscle fiber development + GO:0055013 + cardiac muscle cell development + + + + + The process whose specific outcome is the progression of a cardiac muscle cell over time, from its formation to the mature state. + GOC:devbiol + GOC:mtg_heart + + + + + cardiomyocyte cell development + GOC:mtg_muscle + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the hypochord over time, from its formation to the mature structure. The hypochord is a transient rod-like structure in the embryos of fish, lampreys and amphibians that is located immediately ventral to the notochord. The hypochord may play a role in positioning the dorsal aorta. + subnotochordal rod development + biological_process + GO:0055016 + hypochord development + + + + + The process whose specific outcome is the progression of the hypochord over time, from its formation to the mature structure. The hypochord is a transient rod-like structure in the embryos of fish, lampreys and amphibians that is located immediately ventral to the notochord. The hypochord may play a role in positioning the dorsal aorta. + GOC:devbiol + GOC:lb + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The increase in size or mass of a cardiac muscle, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another. + heart muscle growth + biological_process + GO:0055017 + cardiac muscle tissue growth + + + + + The increase in size or mass of a cardiac muscle, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another. + GOC:devbiol + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of cardiac muscle fiber development. + regulation of cardiac muscle fibre development + regulation of heart muscle fiber development + biological_process + GO:0055018 + regulation of cardiac muscle fiber development + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate or extent of cardiac muscle fiber development. + GOC:vk + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle fiber development. + down regulation of cardiac muscle fiber development + down-regulation of cardiac muscle fiber development + downregulation of cardiac muscle fiber development + negative regulation of cardiac muscle fibre development + inhibition of cardiac muscle fiber development + biological_process + negative regulation of heart muscle fiber development + GO:0055019 + negative regulation of cardiac muscle fiber development + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle fiber development. + GOC:vk + + + + + + + + + + + + + + + + + + + + + + + + + + Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle fiber development. + positive regulation of cardiac muscle fibre development + positive regulation of heart muscle fiber development + up regulation of cardiac muscle fiber development + up-regulation of cardiac muscle fiber development + upregulation of cardiac muscle fiber development + activation of cardiac muscle fiber development + stimulation of cardiac muscle fiber development + biological_process + GO:0055020 + positive regulation of cardiac muscle fiber development + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle fiber development. + GOC:vk + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of cardiac muscle growth. + biological_process + GO:0055021 + regulation of cardiac muscle tissue growth + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate or extent of cardiac muscle growth. + GOC:vk + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle growth. + down regulation of cardiac muscle growth + down-regulation of cardiac muscle growth + downregulation of cardiac muscle growth + inhibition of cardiac muscle growth + biological_process + negative regulation of heart muscle growth + GO:0055022 + negative regulation of cardiac muscle tissue growth + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle growth. + GOC:vk + + + + + + + + + + + + + + + + + + + + Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle growth. + positive regulation of heart muscle growth + up regulation of cardiac muscle growth + up-regulation of cardiac muscle growth + upregulation of cardiac muscle growth + activation of cardiac muscle growth + stimulation of cardiac muscle growth + biological_process + GO:0055023 + positive regulation of cardiac muscle tissue growth + + + + + Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle growth. + GOC:vk + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of cardiac muscle tissue development. + regulation of heart muscle development + biological_process + GO:0055024 + regulation of cardiac muscle tissue development + + + + + Any process that modulates the frequency, rate or extent of cardiac muscle tissue development. + GOC:vk + + + + + + + + + + + + + + + + + + + Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle tissue development. + positive regulation of heart muscle development + up regulation of cardiac muscle development + up-regulation of cardiac muscle development + upregulation of cardiac muscle development + activation of cardiac muscle development + stimulation of cardiac muscle development + biological_process + GO:0055025 + positive regulation of cardiac muscle tissue development + + + + + Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle tissue development. + GOC:vk + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle tissue development. + down regulation of cardiac muscle development + down-regulation of cardiac muscle development + downregulation of cardiac muscle development + negative regulation of heart muscle development + inhibition of cardiac muscle development + biological_process + GO:0055026 + negative regulation of cardiac muscle tissue development + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle tissue development. + GOC:vk + + + + + + + + + + + + + + + + + + + + + + + + + The process resulting in the physical partitioning and separation of a neuroblast into daughter cells. A neuroblast is any cell that will divide and give rise to a neuron. + neuroblast cell division + biological_process + GO:0055057 + neuroblast division + + + + + The process resulting in the physical partitioning and separation of a neuroblast into daughter cells. A neuroblast is any cell that will divide and give rise to a neuron. + PMID:11163136 + PMID:11250167 + + + + + + + + + + + + + + + + + + + + The process resulting in the physical partitioning and separation of a neuroblast into two daughter cells with different developmental potentials. + biological_process + GO:0055059 + asymmetric neuroblast division + + + + + The process resulting in the physical partitioning and separation of a neuroblast into two daughter cells with different developmental potentials. + GOC:dph + + + + + + + + + + + + + + + + + + + + + Any process involved in the maintenance of an internal steady state of metal ions within an organism or cell. + biological_process + GO:0055065 + + + + metal ion homeostasis + + + + + Any process involved in the maintenance of an internal steady state of metal ions within an organism or cell. + GOC:ai + GOC:jid + GOC:mah + + + + + + + + + + + + + + + + + + + + + Any process involved in the maintenance of an internal steady state of monovalent inorganic cations within an organism or cell. + biological_process + GO:0055067 + monovalent inorganic cation homeostasis + + + + + Any process involved in the maintenance of an internal steady state of monovalent inorganic cations within an organism or cell. + GOC:ai + GOC:jid + GOC:mah + + + + + + + + + + + + + + + + + + + Any process involved in the maintenance of an internal steady state of iron ions within an organism or cell. + iron homeostasis + biological_process + GO:0055072 + iron ion homeostasis + + + + + Any process involved in the maintenance of an internal steady state of iron ions within an organism or cell. + GOC:ai + GOC:jid + GOC:mah + + + + + + + + + + + + + + + + + + + + + Any process involved in the maintenance of an internal steady state of calcium ions within an organism or cell. + regulation of calcium ion concentration + biological_process + GO:0055074 + calcium ion homeostasis + + + + + Any process involved in the maintenance of an internal steady state of calcium ions within an organism or cell. + GOC:ceb + GOC:jid + GOC:mah + + + + + + + + + + + + + + + + + + + + + Any process involved in the maintenance of an internal steady state of sodium ions within an organism or cell. + biological_process + GO:0055078 + sodium ion homeostasis + + + + + Any process involved in the maintenance of an internal steady state of sodium ions within an organism or cell. + GOC:ai + GOC:jid + GOC:mah + + + + + + + + + + + + + + + + + + + + Any process involved in the maintenance of an internal steady state of cations within an organism or cell. + biological_process + GO:0055080 + cation homeostasis + + + + + Any process involved in the maintenance of an internal steady state of cations within an organism or cell. + GOC:ceb + GOC:jid + GOC:mah + + + + + + + + + + + + + + + + + + + Any biological process involved in the maintenance of an internal steady state of a chemical at the level of the cell. + biological_process + GO:0055082 + cellular chemical homeostasis + + + + + Any biological process involved in the maintenance of an internal steady state of a chemical at the level of the cell. + GOC:isa_complete + GOC:jid + + + + + + + + + + + + + + + + + + + Any process involved in the maintenance of an internal steady state of lipid within an organism or cell. + biological_process + GO:0055088 + lipid homeostasis + + + + + Any process involved in the maintenance of an internal steady state of lipid within an organism or cell. + GOC:BHF + GOC:rl + + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoprotein particle stimulus. + response to lipoprotein particle stimulus + biological_process + GO:0055094 + response to lipoprotein particle + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoprotein particle stimulus. + GOC:BHF + GOC:rl + + + + + response to lipoprotein particle stimulus + GOC:dos + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The directed movement of proteins from the Golgi to a transport vesicle. Continuously secreted proteins are sorted into transport vesicles that fuse with the plasma membrane, releasing their contents by exocytosis. + biological_process + GO:0055108 + Golgi to transport vesicle transport + + + + + The directed movement of proteins from the Golgi to a transport vesicle. Continuously secreted proteins are sorted into transport vesicles that fuse with the plasma membrane, releasing their contents by exocytosis. + GOC:jid + + + + + + + + + + + + + + + + + + + The migration of individual cells into the embryo involved in deuterostomic gastrulation. + biological_process + GO:0055111 + ingression involved in gastrulation with mouth forming second + + + + + The migration of individual cells into the embryo involved in deuterostomic gastrulation. + ISBN:0878932437 + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of cardiac muscle contraction. + biological_process + GO:0055117 + regulation of cardiac muscle contraction + + + + + Any process that modulates the frequency, rate or extent of cardiac muscle contraction. + GOC:ecd + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle contraction. + biological_process + GO:0055118 + negative regulation of cardiac muscle contraction + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle contraction. + GOC:ecd + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the digestive system over time, from its formation to the mature structure. The digestive system is the entire structure in which digestion takes place. Digestion is all of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. + biological_process + GO:0055123 + digestive system development + + + + + The process whose specific outcome is the progression of the digestive system over time, from its formation to the mature structure. The digestive system is the entire structure in which digestion takes place. Digestion is all of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. + GOC:jid + + + + + + + + + + + + + + + The transmission of vibrations via ossicles to the inner ear. + jid + 2009-10-13T10:59:39Z + biological_process + GO:0055127 + vibrational conductance of sound to the inner ear + + + + + The transmission of vibrations via ossicles to the inner ear. + GOC:mh + + + + + + + + + An automatic response to a stimulus beginning with a nerve impulse from a receptor and ending with the action of an effector such as a gland or a muscle. Signaling never reaches a level of consciousness. + Wikipedia:Reflex + biological_process + GO:0060004 + reflex + + + + + An automatic response to a stimulus beginning with a nerve impulse from a receptor and ending with the action of an effector such as a gland or a muscle. Signaling never reaches a level of consciousness. + GOC:dph + ISBN:0877797099 + + + + + + + + + A reflex process in which a response to an angular or linear acceleration stimulus begins with an afferent nerve impulse from a receptor in the inner ear and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness. + biological_process + GO:0060005 + vestibular reflex + + + + + A reflex process in which a response to an angular or linear acceleration stimulus begins with an afferent nerve impulse from a receptor in the inner ear and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness. + PMID:11784757 + + + + + + + + + A vestibular reflex by which a response to a linear acceleration stimulus begins with an afferent nerve impulse from a receptor in the otolith and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness. + biological_process + GO:0060007 + linear vestibuloocular reflex + + + + + A vestibular reflex by which a response to a linear acceleration stimulus begins with an afferent nerve impulse from a receptor in the otolith and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness. + GOC:dph + PMID:11784757 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules. + biological_process + GO:0060008 + Sertoli cell differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a Sertoli cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a Sertoli cell fate. + biological_process + GO:0060009 + Sertoli cell development + + + + + The process whose specific outcome is the progression of a Sertoli cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a Sertoli cell fate. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + The multiplication or reproduction of Sertoli cells, resulting in the expansion of the Sertoli cell population. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules. + biological_process + GO:0060011 + Sertoli cell proliferation + + + + + The multiplication or reproduction of Sertoli cells, resulting in the expansion of the Sertoli cell population. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules. + GOC:dph + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires the specialized features of a granulosa cell, a supporting cell for the developing female gamete in the ovary of mammals. + biological_process + GO:0060014 + granulosa cell differentiation + + + + + The process in which a relatively unspecialized cell acquires the specialized features of a granulosa cell, a supporting cell for the developing female gamete in the ovary of mammals. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a granulosa cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a granulosa cell fate. + biological_process + GO:0060016 + granulosa cell development + + + + + The process whose specific outcome is the progression of a granulosa cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a granulosa cell fate. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the parathyroid gland over time, from its formation to the mature structure. The parathyroid gland is an organ specialised for secretion of parathyroid hormone. + biological_process + GO:0060017 + parathyroid gland development + + + + + The process whose specific outcome is the progression of the parathyroid gland over time, from its formation to the mature structure. The parathyroid gland is an organ specialised for secretion of parathyroid hormone. + GOC:dph + ISBN:0721662544 + + + + + + + + + + + + + + + + + + + + The biological process whose specific outcome is the progression of the roof of the mouth from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The roof of the mouth is the partition that separates the nasal and oral cavities. + palatum development + biological_process + GO:0060021 + roof of mouth development + + + + + The biological process whose specific outcome is the progression of the roof of the mouth from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The roof of the mouth is the partition that separates the nasal and oral cavities. + GOC:dph + ISBN:0721662544 + + + + + palatum development + ISBN:0721662544 + + + + + + + + + + + + + + + + + + + + + + + + + + + The biological process whose specific outcome is the progression of the hard palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. The hard palate is the anterior portion of the palate consisting of bone and mucous membranes. + palatum durum development + biological_process + GO:0060022 + hard palate development + + + + + The biological process whose specific outcome is the progression of the hard palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. The hard palate is the anterior portion of the palate consisting of bone and mucous membranes. + GOC:dph + ISBN:0721662544 + + + + + palatum durum development + ISBN:0721662544 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The biological process whose specific outcome is the progression of the soft palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. The soft palate is the posterior portion of the palate extending from the posterior edge of the hard palate. + + palatum molle development + velum palatum development + biological_process + GO:0060023 + soft palate development + + + + + The biological process whose specific outcome is the progression of the soft palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. The soft palate is the posterior portion of the palate extending from the posterior edge of the hard palate. + GOC:dph + ISBN:0721662544 + + + + + palatum molle development + ISBN:0721662544 + + + + + velum palatum development + ISBN:0721662544 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the pharyngeal system over time, from its formation to the mature structure. The pharyngeal system is a transient embryonic complex that is specific to vertebrates. It comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal clefts, invaginations of surface ectoderm. The development of the system ends when the stucture it contributes to are forming: the thymus, thyroid, parathyroids, maxilla, mandible, aortic arch, cardiac outflow tract, external and middle ear. + biological_process + GO:0060037 + pharyngeal system development + + + + + The process whose specific outcome is the progression of the pharyngeal system over time, from its formation to the mature structure. The pharyngeal system is a transient embryonic complex that is specific to vertebrates. It comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal clefts, invaginations of surface ectoderm. The development of the system ends when the stucture it contributes to are forming: the thymus, thyroid, parathyroids, maxilla, mandible, aortic arch, cardiac outflow tract, external and middle ear. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The expansion of a cardiac muscle cell population by cell division. + cardiac myocyte proliferation + heart muscle cell proliferation + biological_process + cardiomyocyte proliferation + GO:0060038 + cardiac muscle cell proliferation + + + + + The expansion of a cardiac muscle cell population by cell division. + GOC:dph + GOC:rph + PMID:11161571 + + + + + cardiomyocyte proliferation + GOC:dph + PMID:10074473 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the pericardium over time, from its formation to the mature structure. The pericardium is a double-walled sac that contains the heart and the roots of the aorta, vena cava and the pulmonary artery. + biological_process + GO:0060039 + pericardium development + + + + + The process whose specific outcome is the progression of the pericardium over time, from its formation to the mature structure. The pericardium is a double-walled sac that contains the heart and the roots of the aorta, vena cava and the pulmonary artery. + GOC:dph + GOC:rph + PMID:15138308 + PMID:16376438 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of a bipolar cell, the last neuron to be generated in the retina. + biological_process + GO:0060040 + retinal bipolar neuron differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized features of a bipolar cell, the last neuron to be generated in the retina. + GOC:ascb_2009 + GOC:bf + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates. + GO:0002073 + retina development in camera-style eye + biological_process + retinal development + GO:0060041 + retina development in camera-type eye + + + + + The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates. + GOC:bf + GOC:dph + ISBN:0815340729 + + + + + retinal development + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of the retina is generated and organized. + retina morphogenesis in camera-style eye + retinogenesis + biological_process + GO:0060042 + retina morphogenesis in camera-type eye + + + + + The process in which the anatomical structure of the retina is generated and organized. + GOC:bf + GOC:dph + GOC:mtg_sensu + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of cardiac muscle cell proliferation. + regulation of heart muscle cell proliferation + biological_process + regulation of cardiomyocyte proliferation + GO:0060043 + regulation of cardiac muscle cell proliferation + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate or extent of cardiac muscle cell proliferation. + GOC:dph + GOC:rph + + + + + regulation of cardiomyocyte proliferation + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell proliferation. + negative regulation of heart muscle cell proliferation + biological_process + GO:0060044 + negative regulation of cardiac muscle cell proliferation + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell proliferation. + GOC:dph + GOC:rph + + + + + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of cardiac muscle cell proliferation. + biological_process + positive regulation of heart muscle cell proliferation + GO:0060045 + positive regulation of cardiac muscle cell proliferation + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that activates or increases the frequency, rate or extent of cardiac muscle cell proliferation. + GOC:dph + GOC:rph + + + + + + + + + + + + + + + The multicellular organismal process in which the heart decreases in volume in a characteristic way to propel blood through the body. + heart beating + biological_process + cardiac contraction + hemolymph circulation + GO:0060047 + heart contraction + + + + + The multicellular organismal process in which the heart decreases in volume in a characteristic way to propel blood through the body. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + Muscle contraction of cardiac muscle tissue. + heart muscle contraction + biological_process + GO:0060048 + cardiac muscle contraction + + + + + Muscle contraction of cardiac muscle tissue. + GOC:dph + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the rate or extent of epithelial cell proliferation, contributing to the restoration of integrity to a damaged tissue following an injury. + biological_process + GO:0060054 + positive regulation of epithelial cell proliferation involved in wound healing + + + + + Any process that activates or increases the rate or extent of epithelial cell proliferation, contributing to the restoration of integrity to a damaged tissue following an injury. + GOC:dph + + + + + + + + + + + + + + + + + + + + Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to a damaged tissue, following an injury. + biological_process + GO:0060055 + angiogenesis involved in wound healing + + + + + Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to a damaged tissue, following an injury. + GOC:dph + PMID:15039218 + + + + + + + + + + + + + + + + + + + + + + + + + + + Formation of the specialized region on the dorsalmost side of the embryo that acts as the main signaling center establishing the vertebrate body plan. + Spemann's organizer formation + Spemann-Mangold organizer formation + biological_process + GO:0060061 + Spemann organizer formation + + + + + Formation of the specialized region on the dorsalmost side of the embryo that acts as the main signaling center establishing the vertebrate body plan. + GOC:bf + GOC:dph + + + + + + + + + + + + + + + + + + + + + + The reproductive developmental process whose specific outcome is the progression of the uterus over time, from its formation to the mature structure. + biological_process + Mullerian tract development + GO:0060065 + uterus development + + + + + The reproductive developmental process whose specific outcome is the progression of the uterus over time, from its formation to the mature structure. + GOC:dph + GOC:ebc + + + + + + + + + + + + + + + + + + + + + The reproductive developmental process whose specific outcome is the progression of an oviduct over time, from its formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism. + fallopian tube development + biological_process + Mullerian tract development + GO:0060066 + oviduct development + + + + + The reproductive developmental process whose specific outcome is the progression of an oviduct over time, from its formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism. + GOC:dph + GOC:ebc + http://www.thefreedictionary.com/oviduct + + + + + fallopian tube development + GOC:bf + + + + + + + + + + + + + + + + + + + + The reproductive developmental process whose specific outcome is the progression of the cervix over time, from its formation to the mature structure. + biological_process + Mullerian tract development + GO:0060067 + cervix development + + + + + The reproductive developmental process whose specific outcome is the progression of the cervix over time, from its formation to the mature structure. + GOC:dph + GOC:ebc + + + + + + + + + + + + + + + + + + + + The reproductive developmental process whose specific outcome is the progression of the vagina over time, from its formation to the mature structure. + biological_process + GO:0060068 + vagina development + + + + + The reproductive developmental process whose specific outcome is the progression of the vagina over time, from its formation to the mature structure. + GOC:dph + GOC:ebc + + + + + + + + + + The regulation of body fluids process in which parasympathetic nerves stimulate the bladder wall muscle to contract and expel urine from the body. + Wikipedia:Urination + urination + urine voiding + biological_process + GO:0060073 + micturition + + + + + The regulation of body fluids process in which parasympathetic nerves stimulate the bladder wall muscle to contract and expel urine from the body. + GOC:dph + + + + + + + + + The reflex process in which a mechanical stimulus applied to the eye elicits a response of the eyelid closing. + nictitating membrane reflex + biological_process + GO:0060082 + eye blink reflex + + + + + The reflex process in which a mechanical stimulus applied to the eye elicits a response of the eyelid closing. + GOC:dph + PMID:2913208 + + + + + + + + + + + + + + + + + + + + The process leading to shortening and/or development of tension in the urinary bladder smooth muscle tissue involved in the expulsion urine from the body. + biological_process + smooth muscle contraction involved in urination + urinary bladder smooth muscle contraction involved in micturition + GO:0060083 + smooth muscle contraction involved in micturition + + + + + The process leading to shortening and/or development of tension in the urinary bladder smooth muscle tissue involved in the expulsion urine from the body. + GOC:dph + PMID:15827347 + + + + + urinary bladder smooth muscle contraction involved in micturition + GOC:dph + + + + + + + + + A compound molecular function in which an effector function is controlled by one or more regulatory components. + molecular_function + GO:0060089 + + + + + molecular transducer activity + + + + + A compound molecular function in which an effector function is controlled by one or more regulatory components. + GOC:dos + GOC:pdt + + + + + + + + + + + + + + + The process in which relatively unspecialized cells, acquire specialized structural and/or functional features of inner ear receptor cells. Inner ear receptor cells are mechanorecptors found in the inner ear responsible for transducing signals involved in balance and sensory perception of sound. + inner ear hair cell differentiation + biological_process + GO:0060113 + inner ear receptor cell differentiation + + + + + The process in which relatively unspecialized cells, acquire specialized structural and/or functional features of inner ear receptor cells. Inner ear receptor cells are mechanorecptors found in the inner ear responsible for transducing signals involved in balance and sensory perception of sound. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of an auditory receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. + auditory hair cell development + biological_process + GO:0060117 + auditory receptor cell development + + + + + The process whose specific outcome is the progression of an auditory receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. + GOC:dph + + + + + + + + + + + + + + + The process whose specific outcome is the progression of an inner ear receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. + inner ear hair cell development + biological_process + GO:0060119 + inner ear receptor cell development + + + + + The process whose specific outcome is the progression of an inner ear receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a somatotropin secreting cell. A somatotropin secreting cell is an acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin. + growth hormone secreting cell differentiation + somatotrophin secreting cell differentiation + biological_process + somatotrope differentiation + somatotroph differentiation + somatotropic cell differentiation + somatrophic cell differentiation + GO:0060126 + somatotropin secreting cell differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a somatotropin secreting cell. A somatotropin secreting cell is an acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a prolactin secreting cell. A prolactin secreting cell is an acidophilic cell of the anterior pituitary that produces prolactin. + epsilon-acidophil differentiation + lactotrope differentiation + lactotroph differentiation + lactotropic cell differentiation + mammotrope differentiation + mammotroph differentiation + mammotrophic cell differentiation + mammotropic cell differentiation + biological_process + GO:0060127 + prolactin secreting cell differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a prolactin secreting cell. A prolactin secreting cell is an acidophilic cell of the anterior pituitary that produces prolactin. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a corticotropic hormone secreting cell. An corticotropic hormone secreting cell is a basophil cell of the anterior pituitary that produces corticotropin. + adrenocorticotrophic hormone secreting cell differentiation + adrenocorticotropic hormone secreting cell differentiation + corticotrope differentiation + corticotroph differentiation + biological_process + corticotrophin hormone secreting cell differentiation + GO:0060128 + corticotropin hormone secreting cell differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a corticotropic hormone secreting cell. An corticotropic hormone secreting cell is a basophil cell of the anterior pituitary that produces corticotropin. + GOC:dph + + + + + adrenocorticotropic hormone secreting cell differentiation + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a corticotropic hormone secreting cell over time, from its formation to the mature structure. An corticotropic hormone secreting cell is a basophil cell of the anterior pituitary that produces corticotropin. + adrenocorticotrophic hormone secreting cell development + adrenocorticotropic hormone secreting cell development + corticotrope development + biological_process + corticotroph development + corticotrophin hormone secreting cell development + GO:0060131 + corticotropin hormone secreting cell development + + + + + The process whose specific outcome is the progression of a corticotropic hormone secreting cell over time, from its formation to the mature structure. An corticotropic hormone secreting cell is a basophil cell of the anterior pituitary that produces corticotropin. + GOC:dph + + + + + adrenocorticotropic hormone secreting cell development + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a prolactin secreting cell over time, from its formation to the mature structure. A prolactin secreting cell is an acidophilic cell of the anterior pituitary that produces prolactin. + epsilon-acidophil development + lactotrope development + lactotroph development + lactotropic cell development + mammotrope development + mammotroph development + mammotrophic cell development + mammotropic cell development + biological_process + GO:0060132 + prolactin secreting cell development + + + + + The process whose specific outcome is the progression of a prolactin secreting cell over time, from its formation to the mature structure. A prolactin secreting cell is an acidophilic cell of the anterior pituitary that produces prolactin. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a somatotropin secreting cell over time, from its formation to the mature structure. A somatotropin secreting cell is an acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin. + growth hormone secreting cell development + somatotrophin secreting cell development + somatotropic cell development + biological_process + somatotrope development + somatotroph development + somatrophic cell development + GO:0060133 + somatotropin secreting cell development + + + + + The process whose specific outcome is the progression of a somatotropin secreting cell over time, from its formation to the mature structure. A somatotropin secreting cell is an acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin. + GOC:dph + + + + + + + + + + + + + + + + A reproductive process occurring in the mother that allows an embryo or fetus to develop within it. + biological_process + GO:0060135 + maternal process involved in female pregnancy + + + + + A reproductive process occurring in the mother that allows an embryo or fetus to develop within it. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A reproductive process occurring in the embryo or fetus that allows the embryo or fetus to develop within the mother. + biological_process + GO:0060136 + embryonic process involved in female pregnancy + + + + + A reproductive process occurring in the embryo or fetus that allows the embryo or fetus to develop within the mother. + GOC:dph + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells. + biological_process + GO:0060142 + regulation of syncytium formation by plasma membrane fusion + + + + + Any process that modulates the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells. + GOC:dph + + + + + + + + + + + + + + + + + + + + Any process that increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells. + biological_process + GO:0060143 + positive regulation of syncytium formation by plasma membrane fusion + + + + + Any process that increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A reflex that occurs in response to suckling, beginning with a nerve impulse from a receptor in the mammary gland and ending with the ejection of milk from the gland. Signaling never reaches a level of consciousness. + milk ejection + biological_process + GO:0060156 + milk ejection reflex + + + + + A reflex that occurs in response to suckling, beginning with a nerve impulse from a receptor in the mammary gland and ending with the ejection of milk from the gland. Signaling never reaches a level of consciousness. + GOC:cjm + GOC:dph + GOC:mr + GOC:st + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the urinary bladder over time, from its formation to the mature structure. The urinary bladder is an elastic, muscular sac situated in the anterior part of the pelvic cavity in which urine collects before excretion. + + biological_process + GO:0060157 + urinary bladder development + + + + + The process whose specific outcome is the progression of the urinary bladder over time, from its formation to the mature structure. The urinary bladder is an elastic, muscular sac situated in the anterior part of the pelvic cavity in which urine collects before excretion. + GOC:dph + GOC:ln + GOC:mr + PMID:11768524 + PMID:18276178 + PMID:538956 + + + + + + + + + + + + + + + + + + + + + + + + + The biological process whose specific outcome is the progression of the olfactory pit from an initial condition to its mature state. This process begins with the formation of the olfactory pit, which is an indentation of the olfactory placode, and ends when the pits hollows out to form the nasopharynx. + https://github.com/geneontology/go-ontology/issues/22589 + biological_process + GO:0060166 + olfactory pit development + + + + + The biological process whose specific outcome is the progression of the olfactory pit from an initial condition to its mature state. This process begins with the formation of the olfactory pit, which is an indentation of the olfactory placode, and ends when the pits hollows out to form the nasopharynx. + GOC:dph + ISBN:0124020607 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The portion of the plasma membrane surrounding a cilium. + GO:0020017 + cilial membrane + cilium membrane + flagellar membrane + flagellum membrane + cellular_component + GO:0060170 + Note that cilia and eukaryotic flagella are deemed to be equivalent. + ciliary membrane + + + + + The portion of the plasma membrane surrounding a cilium. + GOC:cilia + GOC:dph + GOC:rph + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a limb over time, from its formation to the mature structure. A limb is an appendage of an animal used for locomotion or grasping. Examples include legs, arms or some types of fin. + Wikipedia:Limb_development + paired limb/fin development + limb bud development + biological_process + GO:0060173 + limb development + + + + + The process whose specific outcome is the progression of a limb over time, from its formation to the mature structure. A limb is an appendage of an animal used for locomotion or grasping. Examples include legs, arms or some types of fin. + GOC:dgh + GOC:dph + PMID:11487378 + + + + + limb bud development + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + The process pertaining to the initial formation of a limb bud from unspecified parts. This process begins with the formation of a local condensation of mesenchyme cells within the prospective limb field, and ends when a limb bud is recognizable. + limb formation + limbbud formation + biological_process + GO:0060174 + limb bud formation + + + + + The process pertaining to the initial formation of a limb bud from unspecified parts. This process begins with the formation of a local condensation of mesenchyme cells within the prospective limb field, and ends when a limb bud is recognizable. + GOC:dgh + GOC:dph + + + + + + + + + The progression of physiological phases, occurring in the endometrium during the estrous cycle that recur at regular intervals during the reproductive years. The estrous cycle is an ovulation cycle where the endometrium is resorbed if pregnancy does not occur. + biological_process + GO:0060206 + + Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). + estrous cycle phase + + + + + The progression of physiological phases, occurring in the endometrium during the estrous cycle that recur at regular intervals during the reproductive years. The estrous cycle is an ovulation cycle where the endometrium is resorbed if pregnancy does not occur. + GOC:dph + + + + + + + + + The estrous cycle phase in which a female is sexually receptive. + oestrus + biological_process + GO:0060209 + + Note that this term should not be used for direct annotation. If you are trying to make an annotation to x phase, it is likely that the correct annotation is 'regulation of x/y phase transition' or to a process which occurs during the reported phase. To capture the phase when a specific location or process is observed, the phase term can be used in an annotation extension (PMID:24885854) applied to a cellular component term (with the relation exists_during) or a biological process term (with the relation happens_during). + estrus + + + + + The estrous cycle phase in which a female is sexually receptive. + GOC:dph + ISBN:0721662544 + + + + + + + + + + + + + + + + + + + + + + + + + + + Formation of the endocardium of the heart. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. + biological_process + GO:0060214 + endocardium formation + + + + + Formation of the endocardium of the heart. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. + GOC:bf + GOC:dph + PMID:17722983 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell in a camera-type eye. + biological_process + GO:0060219 + camera-type eye photoreceptor cell differentiation + + + + + The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell in a camera-type eye. + GOC:ascb_2009 + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires the specialized features of a retinal rod cell. + biological_process + GO:0060221 + retinal rod cell differentiation + + + + + The process in which a relatively unspecialized cell acquires the specialized features of a retinal rod cell. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell. + epithelial cell differentiation from mesenchymal cell + mesenchymal-epithelial transition + biological_process + GO:0060231 + mesenchymal to epithelial transition + + + + + A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell. + GOC:ascb_2009 + GOC:dph + GOC:tb + + + + + epithelial cell differentiation from mesenchymal cell + GOC:BHF + GOC:dph + GOC:rl + + + + + mesenchymal-epithelial transition + GOC:dph + + + + + + + + + A homeostatic process involved in the maintenance of an internal steady state within a defined anatomical structure of an organism, including control of cellular proliferation and death and control of metabolic function. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. + anatomical structure maintenance + biological_process + GO:0060249 + anatomical structure homeostasis + + + + + A homeostatic process involved in the maintenance of an internal steady state within a defined anatomical structure of an organism, including control of cellular proliferation and death and control of metabolic function. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome. + GOC:dph + + + + + anatomical structure maintenance + GOC:dph + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of glial cell proliferation. + biological_process + GO:0060251 + regulation of glial cell proliferation + + + + + Any process that modulates the frequency, rate or extent of glial cell proliferation. + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the rate or extent of glial cell proliferation. + biological_process + GO:0060252 + positive regulation of glial cell proliferation + + + + + Any process that activates or increases the rate or extent of glial cell proliferation. + GOC:dph + GOC:sl + GOC:tb + + + + + + + + + + + + + + + + + + + + Any process that stops or decreases the rate or extent of glial cell proliferation. + biological_process + GO:0060253 + negative regulation of glial cell proliferation + + + + + Any process that stops or decreases the rate or extent of glial cell proliferation. + GOC:dph + GOC:sl + GOC:tb + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. + biological_process + GO:0060255 + regulation of macromolecule metabolic process + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass. + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + Any process that modulates the rate, frequency or extent of the behavior associated with the intake of food. + regulation of feeding behaviour + biological_process + GO:0060259 + regulation of feeding behavior + + + + + Any process that modulates the rate, frequency or extent of the behavior associated with the intake of food. + GOC:BHF + GOC:dph + GOC:tb + + + + + regulation of feeding behaviour + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole. + + + + + + + GO:0042384 + Reactome:R-HSA-5617833.2 + ciliogenesis + cilium formation + microtubule-based flagellum assembly + biological_process + cilium biogenesis + cilium morphogenesis + cilium organization + GO:0060271 + Note that we deem cilium and microtubule-based flagellum to be equivalent. + cilium assembly + + + + + The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole. + GOC:BHF + GOC:cilia + GOC:dph + GOC:kmv + GOC:pr + GOC:vw + ISBN:0198506732 + PMID:13978319 + PMID:27350441 + Reactome:R-HSA-5617833.2 + + + + + cilium biogenesis + GOC:mah + + + + + cilium organization + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. + biological_process + GO:0060281 + regulation of oocyte development + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. + GOC:dph + GOC:tb + PMID:2394318 + + + + + + + + + + + + + + + + + + + Any process that increases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. + biological_process + GO:0060282 + positive regulation of oocyte development + + + + + Any process that increases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + Any process that decreases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. + biological_process + GO:0060283 + negative regulation of oocyte development + + + + + Any process that decreases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell. + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. + biological_process + GO:0060284 + regulation of cell development + + + + + Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. + GOC:dph + GOC:tb + + + + + + + + + + + + + + + Cell motility due to the motion of one or more eukaryotic cilia. A eukaryotic cilium is a specialized organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole. + GO:0071974 + cilium cell motility + microtubule-based flagellar cell motility + biological_process + ciliary cell motility + GO:0060285 + Note that we deem eukaryotic cilia and microtubule-based flagella to be equivalent. + cilium-dependent cell motility + + + + + Cell motility due to the motion of one or more eukaryotic cilia. A eukaryotic cilium is a specialized organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole. + GOC:cilia + GOC:dgh + GOC:dph + GOC:krc + GOC:mlg + GOC:mtg_cambridge_2013 + + + + + + + + + + + + + + + + + + + + + + + + + Movement of cilia mediated by motor proteins that contributes to the movement of a cell. + biological_process + GO:0060294 + cilium movement involved in cell motility + + + + + Movement of cilia mediated by motor proteins that contributes to the movement of a cell. + GOC:BHF + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the rate frequency or extent of cilium movement involved in ciliary motility. + biological_process + GO:0060295 + regulation of cilium movement involved in cell motility + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the rate frequency or extent of cilium movement involved in ciliary motility. + GOC:BHF + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + + The biological process whose specific outcome is the progression of a head from an initial condition to its mature state. The head is the anterior-most division of the body. + biological_process + GO:0060322 + head development + + + + + The biological process whose specific outcome is the progression of a head from an initial condition to its mature state. The head is the anterior-most division of the body. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the head are generated and organized. The head is the anterior-most division of the body. + biological_process + GO:0060323 + head morphogenesis + + + + + The process in which the anatomical structures of the head are generated and organized. The head is the anterior-most division of the body. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + The biological process whose specific outcome is the progression of a face from an initial condition to its mature state. The face is the ventral division of the head. + biological_process + GO:0060324 + face development + + + + + The biological process whose specific outcome is the progression of a face from an initial condition to its mature state. The face is the ventral division of the head. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the face are generated and organized. The face is the ventral division of the head. + biological_process + GO:0060325 + face morphogenesis + + + + + The process in which the anatomical structures of the face are generated and organized. The face is the ventral division of the head. + GOC:dph + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of a process in which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell. + regulation of cellular localisation + biological_process + GO:0060341 + regulation of cellular localization + + + + + Any process that modulates the frequency, rate or extent of a process in which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell. + GOC:dph + GOC:tb + + + + + regulation of cellular localisation + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process of creating a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue. + trabeculation + biological_process + trabecula biogenesis + GO:0060343 + trabecula formation + + + + + The process of creating a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue. + GOC:dph + + + + + trabeculation + GOC:dph + + + + + trabecula biogenesis + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The process of creating a trabecula in the liver. A trabecula is a tissue element in the form of a small beam, strut or rod. + liver trabeculation + biological_process + liver trabecula biogenesis + GO:0060344 + liver trabecula formation + + + + + The process of creating a trabecula in the liver. A trabecula is a tissue element in the form of a small beam, strut or rod. + GOC:dph + + + + + liver trabeculation + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The process of creating a trabecula in the spleen. A trabecula is a tissue element in the form of a small beam, strut or rod. + spleen trabeculation + biological_process + spleen trabecula biogenesis + GO:0060345 + spleen trabecula formation + + + + + The process of creating a trabecula in the spleen. A trabecula is a tissue element in the form of a small beam, strut or rod. + GOC:dph + + + + + spleen trabeculation + GOC:dph + + + + + spleen trabecula biogenesis + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process of creating a trabecula in the bone. A trabecula is a tissue element in the form of a small beam, strut or rod. + bone trabeculation + skeletal trabecula formation + skeletal trabeculation + biological_process + bone trabecula biogenesis + skeletal trabecula biogenesis + GO:0060346 + bone trabecula formation + + + + + The process of creating a trabecula in the bone. A trabecula is a tissue element in the form of a small beam, strut or rod. + GOC:dph + + + + + bone trabeculation + GOC:dph + + + + + skeletal trabecula formation + GOC:dph + + + + + skeletal trabeculation + GOC:dph + + + + + bone trabecula biogenesis + GOC:dph + + + + + skeletal trabecula biogenesis + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process of creating a trabecula in the heart. A trabecula is a tissue element in the form of a small beam, strut or rod. + cardiac trabecula formation + cardiac trabeculation + heart trabeculation + biological_process + heart trabecula biogenesis + GO:0060347 + heart trabecula formation + + + + + The process of creating a trabecula in the heart. A trabecula is a tissue element in the form of a small beam, strut or rod. + GOC:dph + + + + + cardiac trabecula formation + GOC:dph + + + + + cardiac trabeculation + GOC:dph + + + + + heart trabeculation + GOC:dph + + + + + heart trabecula biogenesis + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of bone over time, from its formation to the mature structure. Bone is the hard skeletal connective tissue consisting of both mineral and cellular components. + biological_process + GO:0060348 + bone development + + + + + The process whose specific outcome is the progression of bone over time, from its formation to the mature structure. Bone is the hard skeletal connective tissue consisting of both mineral and cellular components. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which bones are generated and organized. + biological_process + GO:0060349 + bone morphogenesis + + + + + The process in which bones are generated and organized. + GOC:dph + + + + + + + + + + + + + + + + + + + The process in which bones are generated and organized as a result of the conversion of initial cartilaginous anlage into bone. + biological_process + GO:0060350 + endochondral bone morphogenesis + + + + + The process in which bones are generated and organized as a result of the conversion of initial cartilaginous anlage into bone. + GOC:dph + PMID:11680679 + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones. + biological_process + GO:0060351 + cartilage development involved in endochondral bone morphogenesis + + + + + The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones. + GOC:dph + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus. + GO:1903717 + response to ammonia + biological_process + GO:0060359 + response to ammonium ion + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus. + GOC:TermGenie + GO_REF:0000071 + PMID:23509267 + + + + + + + + + Self-propelled movement of an organism from one location to another through the air, usually by means of active wing movement. + biological_process + GO:0060361 + flight + + + + + Self-propelled movement of an organism from one location to another through the air, usually by means of active wing movement. + GOC:dph + + + + + + + + + + + + + + + + + + + + The process in which any suture between cranial bones is generated and organized. + biological_process + GO:0060363 + cranial suture morphogenesis + + + + + The process in which any suture between cranial bones is generated and organized. + GOC:dph + GOC:pr + GOC:sl + + + + + + + + + + + + + + + + + + + + The process in which the frontal suture is generated and organized. + interfrontal suture morphogenesis + biological_process + GO:0060364 + frontal suture morphogenesis + + + + + The process in which the frontal suture is generated and organized. + GOC:dph + GOC:sl + + + + + + + + + + + + + + + + + + + + The process in which the coronal suture is generated and organized. + biological_process + GO:0060365 + coronal suture morphogenesis + + + + + The process in which the coronal suture is generated and organized. + GOC:dph + GOC:sl + + + + + + + + + + + + + + + + + + + + The process in which the lambdoid suture is generated and organized. + biological_process + GO:0060366 + lambdoid suture morphogenesis + + + + + The process in which the lambdoid suture is generated and organized. + GOC:dph + GOC:sl + + + + + + + + + + + + + + + + + + + + The process in which the sagittal suture is generated and organized. + biological_process + GO:0060367 + sagittal suture morphogenesis + + + + + The process in which the sagittal suture is generated and organized. + GOC:dph + GOC:sl + + + + + + + + + + + + + + + + + + + + + Any process that modulates the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow. + biological_process + GO:0060405 + regulation of penile erection + + + + + Any process that modulates the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow. + GOC:add + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + + + Any process that increases the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow. + biological_process + GO:0060406 + positive regulation of penile erection + + + + + Any process that increases the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow. + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow. + biological_process + GO:0060407 + negative regulation of penile erection + + + + + Any process that stops, prevents, or reduces the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow. + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of a cardiac septum is generated and organized. A cardiac septum is a partition that separates parts of the heart. + GO:0003280 + heart septum morphogenesis + biological_process + GO:0060411 + cardiac septum morphogenesis + + + + + The process in which the anatomical structure of a cardiac septum is generated and organized. A cardiac septum is a partition that separates parts of the heart. + GOC:dph + GOC:mtg_heart + + + + + + + + + + + + + + + + + + + + + + + + + + The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another. + interventricular septum morphogenesis + biological_process + GO:0060412 + ventricular septum morphogenesis + + + + + The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another. + GOC:dph + + + + + interventricular septum morphogenesis + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The developmental process in which atrial septum is generated and organized. The atrial septum separates the upper chambers (the atria) of the heart from one another. + GO:0003287 + interatrial septum morphogenesis + biological_process + GO:0060413 + atrial septum morphogenesis + + + + + The developmental process in which atrial septum is generated and organized. The atrial septum separates the upper chambers (the atria) of the heart from one another. + GOC:dph + GOC:mtg_heart + + + + + interatrial septum morphogenesis + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the structure of the smooth muscle tissue surrounding the aorta is generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body. + biological_process + GO:0060414 + aorta smooth muscle tissue morphogenesis + + + + + The process in which the structure of the smooth muscle tissue surrounding the aorta is generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body. + GOC:bf + GOC:dgh + GOC:dph + Wikipedia:Aorta + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of muscle tissue are generated and organized. Muscle tissue consists of a set of cells that are part of an organ and carry out a contractive function. + biological_process + GO:0060415 + muscle tissue morphogenesis + + + + + The process in which the anatomical structures of muscle tissue are generated and organized. Muscle tissue consists of a set of cells that are part of an organ and carry out a contractive function. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + The increase in size or mass of the heart. + biological_process + GO:0060419 + heart growth + + + + + The increase in size or mass of the heart. + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart. + biological_process + GO:0060420 + regulation of heart growth + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart. + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + Any process that increases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart. + biological_process + GO:0060421 + positive regulation of heart growth + + + + + Any process that increases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart. + GOC:BHF + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the lung are generated and organized. + biological_process + GO:0060425 + lung morphogenesis + + + + + The process in which the anatomical structures of the lung are generated and organized. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The biological process whose specific outcome is the progression of a lung vasculature from an initial condition to its mature state. This process begins with the formation of the lung vasculature and ends with the mature structure. The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs. + pulmonary vasculature development + biological_process + GO:0060426 + lung vasculature development + + + + + The biological process whose specific outcome is the progression of a lung vasculature from an initial condition to its mature state. This process begins with the formation of the lung vasculature and ends with the mature structure. The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs. + GOC:dph + GOC:mtg_lung + + + + + pulmonary vasculature development + GOC:dph + GOC:mtg_lung + + + + + + + + + + + + + + + + + + + + + + + + + + The biological process whose specific outcome is the progression of lung connective tissue from an initial condition to its mature state. This process begins with the formation of lung connective tissue and ends with the mature structure. The lung connective tissue is a material made up of fibers forming a framework and support structure for the lungs. + pulmonary connective tissue development + biological_process + GO:0060427 + lung connective tissue development + + + + + The biological process whose specific outcome is the progression of lung connective tissue from an initial condition to its mature state. This process begins with the formation of lung connective tissue and ends with the mature structure. The lung connective tissue is a material made up of fibers forming a framework and support structure for the lungs. + GOC:dph + GOC:mtg_lung + + + + + + + + + + + + + + + + + + + + + + + + + + The biological process whose specific outcome is the progression of the lung epithelium from an initial condition to its mature state. This process begins with the formation of lung epithelium and ends with the mature structure. The lung epithelium is the specialized epithelium that lines the inside of the lung. + pulmonary epithelium development + biological_process + GO:0060428 + lung epithelium development + + + + + The biological process whose specific outcome is the progression of the lung epithelium from an initial condition to its mature state. This process begins with the formation of lung epithelium and ends with the mature structure. The lung epithelium is the specialized epithelium that lines the inside of the lung. + GOC:dph + GOC:mtg_lung + + + + + pulmonary epithelium development + GOC:dph + GOC:mtg_lung + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of an epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. + biological_process + GO:0060429 + + epithelium development + + + + + The process whose specific outcome is the progression of an epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. + GOC:dph + GOC:mtg_lung + + + + + + + + + + + + + + + + + + + + + + + + + + + The biological process whose specific outcome is the progression of a lung saccule from an initial condition to its mature state. The lung saccule is the primitive gas exchange portion of the lung composed of type I and type II cells. + lung saccular development + biological_process + GO:0060430 + lung saccule development + + + + + The biological process whose specific outcome is the progression of a lung saccule from an initial condition to its mature state. The lung saccule is the primitive gas exchange portion of the lung composed of type I and type II cells. + GOC:dph + GOC:mtg_lung + + + + + lung saccular development + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + The morphogenetic process in which the foregut region specified to become the lung forms the initial left and right buds. + lung formation + biological_process + GO:0060431 + primary lung bud formation + + + + + The morphogenetic process in which the foregut region specified to become the lung forms the initial left and right buds. + GOC:dph + GOC:mtg_lung + + + + + lung formation + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + The biological process whose specific outcome is the progression of a bronchus from an initial condition to its mature state. This process begins with the formation of the bronchus and ends with the mature structure. The bronchus is the portion of the airway that connects to the lungs. + biological_process + GO:0060433 + bronchus development + + + + + The biological process whose specific outcome is the progression of a bronchus from an initial condition to its mature state. This process begins with the formation of the bronchus and ends with the mature structure. The bronchus is the portion of the airway that connects to the lungs. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the bronchus is generated and organized. The bronchus is the portion of the airway that connects to the lungs. + biological_process + GO:0060434 + bronchus morphogenesis + + + + + The process in which the bronchus is generated and organized. The bronchus is the portion of the airway that connects to the lungs. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + The biological process whose specific outcome is the progression of a bronchiole from an initial condition to its mature state. This process begins with the formation of the bronchiole and ends with the mature structure. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi. + biological_process + GO:0060435 + bronchiole development + + + + + The biological process whose specific outcome is the progression of a bronchiole from an initial condition to its mature state. This process begins with the formation of the bronchiole and ends with the mature structure. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi. + GOC:dph + GOC:mtg_lung + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a bronchiole is generated and organized. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi. + biological_process + GO:0060436 + bronchiole morphogenesis + + + + + The process in which a bronchiole is generated and organized. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The increase in size or mass of a lung. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax. + biological_process + GO:0060437 + lung growth + + + + + The increase in size or mass of a lung. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a trachea over time, from its formation to the mature structure. The trachea is the portion of the airway that attaches to the bronchi as it branches. + biological_process + GO:0060438 + trachea development + + + + + The process whose specific outcome is the progression of a trachea over time, from its formation to the mature structure. The trachea is the portion of the airway that attaches to the bronchi as it branches. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a trachea is generated and organized. The trachea is the portion of the airway that attaches to the bronchi as it branches. + biological_process + GO:0060439 + trachea morphogenesis + + + + + The process in which a trachea is generated and organized. The trachea is the portion of the airway that attaches to the bronchi as it branches. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The process pertaining to the initial formation of a trachea from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the trachea is recognizable. The trachea is the portion of the airway that attaches to the bronchi as it branches. + biological_process + GO:0060440 + trachea formation + + + + + The process pertaining to the initial formation of a trachea from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the trachea is recognizable. The trachea is the portion of the airway that attaches to the bronchi as it branches. + GOC:dph + + + + + + + + + + + + + + + + + + + The process in which a highly ordered sequence of patterning events generates the branched epithelial tubes of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units. + lung branching morphogenesis + biological_process + GO:0060441 + epithelial tube branching involved in lung morphogenesis + + + + + The process in which a highly ordered sequence of patterning events generates the branched epithelial tubes of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units. + GOC:dph + GOC:mtg_lung + + + + + lung branching morphogenesis + GOC:dph + + + + + + + + + + + + + + + + + + + + The process in which the branching structure of the prostate gland is generated and organized. A branch is a division or offshoot from a main stem. + prostate gland branching morphogenesis + biological_process + prostate branching + GO:0060442 + branching involved in prostate gland morphogenesis + + + + + The process in which the branching structure of the prostate gland is generated and organized. A branch is a division or offshoot from a main stem. + GOC:dph + + + + + prostate gland branching morphogenesis + GOC:dph + + + + + prostate branching + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which anatomical structures of the mammary gland are generated and organized. Morphogenesis refers to the creation of shape. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. + biological_process + GO:0060443 + mammary gland morphogenesis + + + + + The process in which anatomical structures of the mammary gland are generated and organized. Morphogenesis refers to the creation of shape. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. + GOC:dph + + + + + + + + + + + + + + + + + + + + The process in which the branching structure of the mammary gland duct is generated and organized. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. + mammary gland branching morphogenesis + biological_process + GO:0060444 + branching involved in mammary gland duct morphogenesis + + + + + The process in which the branching structure of the mammary gland duct is generated and organized. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. + GOC:dph + + + + + mammary gland branching morphogenesis + GOC:dph + + + + + + + + + + + + + + + + + + + The process in which the branching structure of the salivary gland is generated and organized. + biological_process + GO:0060445 + branching involved in salivary gland morphogenesis + + + + + The process in which the branching structure of the salivary gland is generated and organized. + GOC:dph + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of branches in the open tracheal system are generated and organized. + biological_process + GO:0060446 + branching involved in open tracheal system development + + + + + The process in which the anatomical structures of branches in the open tracheal system are generated and organized. + GOC:dph + + + + + + + + + + + + + + + + + + + Any process that increases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine. + biological_process + GO:0060450 + positive regulation of hindgut contraction + + + + + Any process that increases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine. + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + Any process that decreases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine. + biological_process + GO:0060451 + negative regulation of hindgut contraction + + + + + Any process that decreases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine. + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + + + Any process that increases the frequency, rate or extent of cardiac muscle contraction. + biological_process + GO:0060452 + positive regulation of cardiac muscle contraction + + + + + Any process that increases the frequency, rate or extent of cardiac muscle contraction. + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + + Any process that modulates the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion. + biological_process + GO:0060453 + regulation of gastric acid secretion + + + + + Any process that modulates the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion. + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + + + Any process that increases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion. + biological_process + GO:0060454 + positive regulation of gastric acid secretion + + + + + Any process that increases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion. + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + + + Any process that decreases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion. + biological_process + GO:0060455 + negative regulation of gastric acid secretion + + + + + Any process that decreases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion. + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + + Any process that increases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. + biological_process + GO:0060456 + positive regulation of digestive system process + + + + + Any process that increases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + + Any process that decreases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. + biological_process + GO:0060457 + negative regulation of digestive system process + + + + + Any process that decreases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism. + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + The biological process whose specific outcome is the progression of a right lung from an initial condition to its mature state. This process begins with the formation of the right lung and ends with the mature structure. The right lung is the lung which is on the right side of the anterior posterior axis looking from a dorsal to ventral aspect. + right pulmonary development + biological_process + GO:0060458 + right lung development + + + + + The biological process whose specific outcome is the progression of a right lung from an initial condition to its mature state. This process begins with the formation of the right lung and ends with the mature structure. The right lung is the lung which is on the right side of the anterior posterior axis looking from a dorsal to ventral aspect. + GOC:dph + GOC:mtg_lung + + + + + right pulmonary development + GOC:dph + GOC:mtg_lung + + + + + + + + + + + + + + + + + + + + The biological process whose specific outcome is the progression of a left lung from an initial condition to its mature state. This process begins with the formation of the left lung and ends with the mature structure. The left lung is the lung which is on the left side of the anterior posterior axis looking from a dorsal to ventral aspect. + left pulmonary development + biological_process + GO:0060459 + left lung development + + + + + The biological process whose specific outcome is the progression of a left lung from an initial condition to its mature state. This process begins with the formation of the left lung and ends with the mature structure. The left lung is the lung which is on the left side of the anterior posterior axis looking from a dorsal to ventral aspect. + GOC:dph + GOC:mtg_lung + + + + + left pulmonary development + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which anatomical structures of the left lung are generated and organized. + biological_process + GO:0060460 + left lung morphogenesis + + + + + The process in which anatomical structures of the left lung are generated and organized. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which anatomical structures of the right lung are generated and organized. + biological_process + GO:0060461 + right lung morphogenesis + + + + + The process in which anatomical structures of the right lung are generated and organized. + GOC:dph + GOC:mtg_lung + + + + + + + + + + + + + + + + + + + + + + + + + + + The biological process whose specific outcome is the progression of a lung lobe from an initial condition to its mature state. This process begins with the formation of a lung lobe by branching morphogenesis and ends with the mature structure. A lung lobe is one of the rounded projections that compose the lung. + biological_process + GO:0060462 + lung lobe development + + + + + The biological process whose specific outcome is the progression of a lung lobe from an initial condition to its mature state. This process begins with the formation of a lung lobe by branching morphogenesis and ends with the mature structure. A lung lobe is one of the rounded projections that compose the lung. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of a lung lobe are generated and organized. A lung lobe is a projection that extends from the lung. + biological_process + GO:0060463 + lung lobe morphogenesis + + + + + The process in which the anatomical structures of a lung lobe are generated and organized. A lung lobe is a projection that extends from the lung. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + The developmental process pertaining to the initial formation of a lung lobe from unspecified parts. This process begins with the specific processes that contribute to the appearance of the lobe and ends when the structural rudiment is recognizable. A lung lobe is a projection that extends from the lung. + biological_process + GO:0060464 + lung lobe formation + + + + + The developmental process pertaining to the initial formation of a lung lobe from unspecified parts. This process begins with the specific processes that contribute to the appearance of the lobe and ends when the structural rudiment is recognizable. A lung lobe is a projection that extends from the lung. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + The biological process whose specific outcome is the progression of a pharynx from an initial condition to its mature state. The pharynx is the part of the digestive system immediately posterior to the mouth. + biological_process + pharyngeal development + GO:0060465 + pharynx development + + + + + The biological process whose specific outcome is the progression of a pharynx from an initial condition to its mature state. The pharynx is the part of the digestive system immediately posterior to the mouth. + GOC:dph + GOC:rk + + + + + + + + + + + + + + + + + + + Any process that decreases the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy). + biological_process + GO:0060467 + negative regulation of fertilization + + + + + Any process that decreases the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy). + GOC:dph + + + + + + + + + + + + + + + + + + + The negative regulation of fertilization process that takes place as part of egg activation, ensuring that only a single sperm fertilizes the egg. + negative regulation of fertilization involved in egg activation + polyspermy block + biological_process + GO:0060468 + prevention of polyspermy + + + + + The negative regulation of fertilization process that takes place as part of egg activation, ensuring that only a single sperm fertilizes the egg. + GOC:dph + + + + + negative regulation of fertilization involved in egg activation + GOC:dph + + + + + polyspermy block + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the controlled movement of a flagellated sperm cell is initiated as part of the process required for flagellated sperm to reach fertilization competence. + biological_process + positive regulation of sperm motility involved in capacitation + GO:0060474 + positive regulation of flagellated sperm motility involved in capacitation + + + + + The process in which the controlled movement of a flagellated sperm cell is initiated as part of the process required for flagellated sperm to reach fertilization competence. + GOC:cilia + GOC:dph + GOC:krc + + + + + + + + + + + + + + + The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate. + pulmonary cell differentiation + biological_process + GO:0060479 + lung cell differentiation + + + + + The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate. + GOC:dph + GOC:mtg_lung + + + + + pulmonary cell differentiation + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The biological process whose specific outcome is the progression of a lobar bronchus epithelium from an initial condition to its mature state. This process begins with the formation of the lobar bronchus epithelium and ends with the mature structure. The lobar bronchus epithelium is the tissue made up of epithelial cells that lines the inside of the lobar bronchus. + biological_process + GO:0060481 + lobar bronchus epithelium development + + + + + The biological process whose specific outcome is the progression of a lobar bronchus epithelium from an initial condition to its mature state. This process begins with the formation of the lobar bronchus epithelium and ends with the mature structure. The lobar bronchus epithelium is the tissue made up of epithelial cells that lines the inside of the lobar bronchus. + GOC:dph + GOC:mtg_lung + + + + + + + + + + + + + + + + + + + + The biological process whose specific outcome is the progression of a lobar bronchus from an initial condition to its mature state. This process begins with the formation of the lobar bronchus and ends with the mature structure. The lobar bronchus is the major airway within the respiratory tree that starts by division of the principal bronchi on both sides and ends at the point of its own subdivision into tertiary or segmental bronchi. + biological_process + GO:0060482 + lobar bronchus development + + + + + The biological process whose specific outcome is the progression of a lobar bronchus from an initial condition to its mature state. This process begins with the formation of the lobar bronchus and ends with the mature structure. The lobar bronchus is the major airway within the respiratory tree that starts by division of the principal bronchi on both sides and ends at the point of its own subdivision into tertiary or segmental bronchi. + GOC:dph + GOC:mtg_lung + + + + + + + + + + + + + + + + + + + + + + + + + + The biological process whose specific outcome is the progression of a lobar bronchus mesenchyme from an initial condition to its mature state. This process begins with the formation of the lobar bronchus mesenchyme and ends with the mature structure. The lobar bronchus mesenchyme is the mass of tissue composed of mesenchymal cells in the lobar bronchus. + biological_process + GO:0060483 + lobar bronchus mesenchyme development + + + + + The biological process whose specific outcome is the progression of a lobar bronchus mesenchyme from an initial condition to its mature state. This process begins with the formation of the lobar bronchus mesenchyme and ends with the mature structure. The lobar bronchus mesenchyme is the mass of tissue composed of mesenchymal cells in the lobar bronchus. + GOC:dph + GOC:mtg_lung + + + + + + + + + + + + + + + The biological process whose specific outcome is the progression of a lung-associated mesenchyme from an initial condition to its mature state. This process begins with the formation of lung-associated mesenchyme and ends with the mature structure. Lung-associated mesenchyme is the tissue made up of loosely connected mesenchymal cells in the lung. + lung mesenchyme development + pulmonary mesenchyme development + biological_process + GO:0060484 + lung-associated mesenchyme development + + + + + The biological process whose specific outcome is the progression of a lung-associated mesenchyme from an initial condition to its mature state. This process begins with the formation of lung-associated mesenchyme and ends with the mature structure. Lung-associated mesenchyme is the tissue made up of loosely connected mesenchymal cells in the lung. + GOC:dph + GOC:mtg_lung + + + + + lung mesenchyme development + GOC:dph + + + + + pulmonary mesenchyme development + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a mesenchymal tissue over time, from its formation to the mature structure. A mesenchymal tissue is made up of loosely packed stellate cells. + mesenchymal development + biological_process + GO:0060485 + mesenchyme development + + + + + The process whose specific outcome is the progression of a mesenchymal tissue over time, from its formation to the mature structure. A mesenchymal tissue is made up of loosely packed stellate cells. + GOC:dph + + + + + mesenchymal development + GOC:dph + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of a club cell. A club cell is an unciliated epithelial cell found in the respiratory and terminal bronchioles. + Clara cell differentiation + biological_process + GO:0060486 + club cell differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized features of a club cell. A club cell is an unciliated epithelial cell found in the respiratory and terminal bronchioles. + GOC:dph + GOC:mtg_lung + PMID:28144783 + + + + + Clara cell differentiation + PMID:28144783 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell that contributes to the epithelium of the lung. + biological_process + pulmonary epithelial cell differentiation + GO:0060487 + lung epithelial cell differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell that contributes to the epithelium of the lung. + GOC:dph + + + + + pulmonary epithelial cell differentiation + GOC:dph + + + + + + + + + + + + + + + + + + + The process in which a branch forms along the side of the lung epithelial tube. + biological_process + GO:0060490 + lateral sprouting involved in lung morphogenesis + + + + + The process in which a branch forms along the side of the lung epithelial tube. + GOC:dph + GOC:mtg_lung + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the rate, frequency, or extent of cell projection assembly. + biological_process + regulation of cell projection formation + GO:0060491 + regulation of cell projection assembly + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the rate, frequency, or extent of cell projection assembly. + GOC:dph + GOC:tb + + + + + regulation of cell projection formation + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + Any process that mediates the transfer of information from one cell to another and contributes to the progression of the lung, from its initial state to the mature structure. + cell-cell signalling involved in lung development + biological_process + GO:0060495 + cell-cell signaling involved in lung development + + + + + Any process that mediates the transfer of information from one cell to another and contributes to the progression of the lung, from its initial state to the mature structure. + GOC:dph + GOC:mtg_lung + + + + + cell-cell signalling involved in lung development + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung attaining its shape. + biological_process + GO:0060501 + positive regulation of epithelial cell proliferation involved in lung morphogenesis + + + + + Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung attaining its shape. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the lung. + biological_process + GO:0060502 + epithelial cell proliferation involved in lung morphogenesis + + + + + The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the lung. + GOC:dph + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of a type I pneumocyte. A type I pneumocyte is a flattened cell with greatly attenuated cytoplasm and a paucity of organelles. + membranous pneumocyte differentiation + biological_process + small alveolar cell differentiation + squamous alveolar cell differentiation + GO:0060509 + type I pneumocyte differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized features of a type I pneumocyte. A type I pneumocyte is a flattened cell with greatly attenuated cytoplasm and a paucity of organelles. + GOC:dph + GOC:mtg_lung + ISBN:0721662544 + + + + + membranous pneumocyte differentiation + GOC:dph + ISBN:0721662544 + + + + + small alveolar cell differentiation + GOC:dph + ISBN:0721662544 + + + + + squamous alveolar cell differentiation + GOC:dph + ISBN:0721662544 + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of a type II pneumocyte. A type II pneumocyte is a surfactant secreting cell that contains abundant cytoplasm containing numerous lipid-rich multilamellar bodies. + great alveolar cell differentiation + biological_process + granular pneumocyte differentiation + large alveolar cell differentiation + GO:0060510 + type II pneumocyte differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized features of a type II pneumocyte. A type II pneumocyte is a surfactant secreting cell that contains abundant cytoplasm containing numerous lipid-rich multilamellar bodies. + GOC:dph + GOC:mtg_lung + ISBN:0721662544 + + + + + great alveolar cell differentiation + GOC:dph + ISBN:0721662544 + + + + + granular pneumocyte differentiation + GOC:dph + ISBN:0721662544 + + + + + large alveolar cell differentiation + GOC:dph + ISBN:0721662544 + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of a prostate gland are generated and organized. + biological_process + GO:0060512 + prostate gland morphogenesis + + + + + The process in which the anatomical structures of a prostate gland are generated and organized. + GOC:dph + PMID:18977204 + + + + + + + + + + + + + + + + + + + + + + + + The morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth. + primary prostate bud formation + prostate ductal budding + prostate gland formation + biological_process + GO:0060513 + prostatic bud formation + + + + + The morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth. + GOC:dph + PMID:18977204 + + + + + primary prostate bud formation + GOC:dph + + + + + prostate ductal budding + GOC:dph + PMID:11401393 + + + + + prostate gland formation + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of a glandular acinus of the prostate gland over time, from its initial formation to the mature structure. The glandular acini are the saclike structures of the gland. + biological_process + GO:0060525 + prostate glandular acinus development + + + + + The progression of a glandular acinus of the prostate gland over time, from its initial formation to the mature structure. The glandular acini are the saclike structures of the gland. + GOC:dph + PMID:18977204 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the prostate glandular acini are generated and organized. The glandular acini are the saclike structures of the gland. + biological_process + GO:0060526 + prostate glandular acinus morphogenesis + + + + + The process in which the prostate glandular acini are generated and organized. The glandular acini are the saclike structures of the gland. + GOC:dph + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the prostate glandular acinus. + biological_process + GO:0060530 + smooth muscle cell differentiation involved in prostate glandular acinus development + + + + + The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the prostate glandular acinus. + GOC:dph + PMID:18977204 + + + + + + + + + + + + + + + + + + + + The process in which relatively unspecialized cells acquires specialized structural and functions of a neuroendocrine cell of the prostate gland acinus. + biological_process + GO:0060531 + neuroendocrine cell differentiation involved in prostate gland acinus development + + + + + The process in which relatively unspecialized cells acquires specialized structural and functions of a neuroendocrine cell of the prostate gland acinus. + GOC:dph + PMID:18977204 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of lung cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. + dph + 2009-04-10T08:12:06Z + pulmonary cartilage development + biological_process + GO:0060532 + bronchus cartilage development + + + + + The process whose specific outcome is the progression of lung cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. + GOC:dph + GOC:mtg_lung + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the bronchus cartilage is generated and organized. The bronchus cartilage is the connective tissue of the portion of the airway that connects to the lungs. + dph + 2009-04-10T08:47:41Z + biological_process + GO:0060533 + bronchus cartilage morphogenesis + + + + + The process in which the bronchus cartilage is generated and organized. The bronchus cartilage is the connective tissue of the portion of the airway that connects to the lungs. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the tracheal cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. + dph + 2009-04-10T09:00:18Z + biological_process + GO:0060534 + trachea cartilage development + + + + + The process whose specific outcome is the progression of the tracheal cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of cartilage in the trachea are generated and organized. + dph + 2009-04-10T09:07:48Z + biological_process + GO:0060535 + trachea cartilage morphogenesis + + + + + The process in which the anatomical structures of cartilage in the trachea are generated and organized. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of cartilage are generated and organized. + dph + 2009-04-10T09:13:27Z + biological_process + GO:0060536 + cartilage morphogenesis + + + + + The process in which the anatomical structures of cartilage are generated and organized. + GOC:dph + + + + + + + + + + + + + + + + + + + + The progression of muscle tissue over time, from its initial formation to its mature state. Muscle tissue is a contractile tissue made up of actin and myosin fibers. + dph + 2009-04-10T08:05:37Z + biological_process + GO:0060537 + muscle tissue development + + + + + The progression of muscle tissue over time, from its initial formation to its mature state. Muscle tissue is a contractile tissue made up of actin and myosin fibers. + GOC:dph + + + + + + + + + + + + + + + + + + + + The progression of a skeletal muscle organ over time from its initial formation to its mature state. A skeletal muscle organ includes the skeletal muscle tissue and its associated connective tissue. + dph + 2009-04-10T08:25:12Z + biological_process + GO:0060538 + skeletal muscle organ development + + + + + The progression of a skeletal muscle organ over time from its initial formation to its mature state. A skeletal muscle organ includes the skeletal muscle tissue and its associated connective tissue. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the diaphragm over time from its initial formation to the mature structure. The diaphragm is a skeletal muscle that is responsible for contraction and expansion of the lungs. + + dph + 2009-04-10T08:44:56Z + biological_process + GO:0060539 + diaphragm development + + + + + The progression of the diaphragm over time from its initial formation to the mature structure. The diaphragm is a skeletal muscle that is responsible for contraction and expansion of the lungs. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the diaphragm are generated and organized. + + dph + 2009-04-10T08:47:51Z + biological_process + GO:0060540 + diaphragm morphogenesis + + + + + The process in which the anatomical structures of the diaphragm are generated and organized. + GOC:dph + + + + + + + + + + + + + + + + + + + + The progression of the respiratory system over time from its formation to its mature structure. The respiratory system carries out respiratory gaseous exchange. + dph + 2009-04-10T08:55:42Z + biological_process + GO:0060541 + + respiratory system development + + + + + The progression of the respiratory system over time from its formation to its mature structure. The respiratory system carries out respiratory gaseous exchange. + GOC:dph + + + + + + + + + + + + + + + + + + + + The increase in size or mass of an anatomical structure that contributes to the structure attaining its shape. + dph + 2009-04-28T08:42:53Z + differential growth + biological_process + GO:0060560 + developmental growth involved in morphogenesis + + + + + The increase in size or mass of an anatomical structure that contributes to the structure attaining its shape. + GOC:dph + + + + + differential growth + GOC:dph + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of a tube are generated and organized from an epithelium. Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system. + dph + 2009-04-28T09:33:36Z + biological_process + GO:0060562 + epithelial tube morphogenesis + + + + + The process in which the anatomical structures of a tube are generated and organized from an epithelium. Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system. + GOC:dph + + + + + + + + + + + + + + + + + + + + The morphogenetic process in which an epithelial sheet bends along a linear axis. + dph + 2009-04-30T09:27:17Z + epithelial folding + biological_process + folding of an epithelial sheet + GO:0060571 + morphogenesis of an epithelial fold + + + + + The morphogenetic process in which an epithelial sheet bends along a linear axis. + GOC:dph + + + + + epithelial folding + GOC:dph + + + + + folding of an epithelial sheet + GOC:dph + + + + + + + + + + + + + + + + + + + + The morphogenetic process in which a bud forms from an epithelial sheet. A bud is a protrusion that forms form the sheet by localized folding. + dph + 2009-04-30T09:38:35Z + biological_process + GO:0060572 + morphogenesis of an epithelial bud + + + + + The morphogenetic process in which a bud forms from an epithelial sheet. A bud is a protrusion that forms form the sheet by localized folding. + GOC:dph + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of the pulmonary venous blood vessels are generated and organized. Pulmonary veins are blood vessels that transport blood from the lungs to the heart. + dph + 2009-05-06T08:44:04Z + biological_process + pulmonary venous blood vessel morphogenesis + GO:0060577 + pulmonary vein morphogenesis + + + + + The process in which the anatomical structure of the pulmonary venous blood vessels are generated and organized. Pulmonary veins are blood vessels that transport blood from the lungs to the heart. + GOC:dph + + + + + pulmonary venous blood vessel morphogenesis + GOC:dph + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of superior vena cava generated and organized. The superior vena cava is a blood vessel that transports blood from the upper body to the heart. + dph + 2009-05-06T08:47:21Z + biological_process + GO:0060578 + superior vena cava morphogenesis + + + + + The process in which the anatomical structure of superior vena cava generated and organized. The superior vena cava is a blood vessel that transports blood from the upper body to the heart. + GOC:dph + + + + + + + + + + + + + + + + + + + The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells within a field of cells that will exhibit a certain pattern of differentiation. Positional information is established through protein signals that emanate from a localized source within a developmental field resulting in specification of a cell type. Those signals are then interpreted in a cell-autonomous manner resulting in the determination of the cell type. + dph + 2009-05-07T12:40:55Z + biological_process + GO:0060581 + cell fate commitment involved in pattern specification + + + + + The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells within a field of cells that will exhibit a certain pattern of differentiation. Positional information is established through protein signals that emanate from a localized source within a developmental field resulting in specification of a cell type. Those signals are then interpreted in a cell-autonomous manner resulting in the determination of the cell type. + GOC:dph + + + + + + + + + + + + + + + + + + + + + Any process involved in the maintenance of the distribution of iron stores within tissues and organs of a multicellular organism. + dph + 2009-05-08T02:18:21Z + biological_process + GO:0060586 + multicellular organismal iron ion homeostasis + + + + + Any process involved in the maintenance of the distribution of iron stores within tissues and organs of a multicellular organism. + GOC:dph + GOC:hjd + GOC:tb + + + + + + + + + + + + + + + + + + + + + + + + + + + The process pertaining to the initial formation of the mammary gland from unspecified parts. The process begins with formation of the mammary line and ends when the solid mammary bud invades the primary mammary mesenchyme. + dph + 2009-05-13T08:47:52Z + mammary line formation + mammary placode formation + biological_process + mammary bud formation + mammary sprout formation + GO:0060592 + mammary gland formation + + + + + The process pertaining to the initial formation of the mammary gland from unspecified parts. The process begins with formation of the mammary line and ends when the solid mammary bud invades the primary mammary mesenchyme. + GOC:dph + PMID:16168142 + PMID:17120154 + + + + + mammary line formation + GOC:dph + + + + + mammary placode formation + GOC:dph + + + + + mammary bud formation + GOC:dph + + + + + mammary sprout formation + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The developmental process in which the mammary placode forms. The mammary placode is a transient lens shaped structure that will give rise to the mammary bud proper. + dph + 2009-05-13T11:55:20Z + biological_process + GO:0060596 + mammary placode formation + + + + + The developmental process in which the mammary placode forms. The mammary placode is a transient lens shaped structure that will give rise to the mammary bud proper. + GOC:dph + PMID:16168142 + + + + + + + + + + + + + + + + + + + The process in which a branch forms along the side of a mammary duct. + dph + 2009-05-13T12:38:06Z + mammary gland duct secondary branching + biological_process + GO:0060599 + lateral sprouting involved in mammary gland duct morphogenesis + + + + + The process in which a branch forms along the side of a mammary duct. + GOC:dph + PMID:17120154 + + + + + mammary gland duct secondary branching + GOC:dph + + + + + + + + + + + + + + + The process in which a branch forms along the side of an epithelium. + dph + 2009-05-14T02:33:01Z + biological_process + GO:0060601 + lateral sprouting from an epithelium + + + + + The process in which a branch forms along the side of an epithelium. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which anatomical structures of the mammary ducts are generated and organized. Mammary ducts are epithelial tubes that transport milk. + dph + 2009-05-15T09:22:25Z + biological_process + GO:0060603 + mammary gland duct morphogenesis + + + + + The process in which anatomical structures of the mammary ducts are generated and organized. Mammary ducts are epithelial tubes that transport milk. + GOC:dph + PMID:17120154 + + + + + + + + + + + + + + + + + + + + The formation of a lumen by hollowing out a solid rod or cord. + dph + 2009-05-15T09:39:49Z + biological_process + GO:0060605 + tube lumen cavitation + + + + + The formation of a lumen by hollowing out a solid rod or cord. + GOC:dph + + + + + + + + + Creation of the central hole of a tube in an anatomical structure by sealing the edges of an epithelial fold. + dph + 2009-05-15T09:44:07Z + biological_process + GO:0060606 + tube closure + + + + + Creation of the central hole of a tube in an anatomical structure by sealing the edges of an epithelial fold. + GOC:dph + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of a mammary gland mesenchymal cell. Mammary gland mesenchymal cells form a loosely connected network of cells that surround the mammary ducts. + dph + 2009-05-15T12:17:06Z + mammary gland mesenchymal cell differentiation + biological_process + GO:0060610 + mesenchymal cell differentiation involved in mammary gland development + + + + + The process in which a relatively unspecialized cell acquires specialized features of a mammary gland mesenchymal cell. Mammary gland mesenchymal cells form a loosely connected network of cells that surround the mammary ducts. + GOC:dph + + + + + mammary gland mesenchymal cell differentiation + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the mammary gland fat over time, from its formation to the mature structure. The mammary fat is an adipose structure in the gland that is invaded by the mammary ducts. + dph + 2009-05-15T12:27:57Z + biological_process + GO:0060611 + mammary gland fat development + + + + + The progression of the mammary gland fat over time, from its formation to the mature structure. The mammary fat is an adipose structure in the gland that is invaded by the mammary ducts. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of adipose tissue over time, from its formation to the mature structure. Adipose tissue is specialized tissue that is used to store fat. + dph + 2009-05-15T12:36:28Z + biological_process + adipogenesis + GO:0060612 + adipose tissue development + + + + + The process whose specific outcome is the progression of adipose tissue over time, from its formation to the mature structure. Adipose tissue is specialized tissue that is used to store fat. + GOC:dph + + + + + adipogenesis + GOC:mah + GOC:sl + + + + + + + + + + + + + + + + + + + + The progression of a fat pad from its initial formation to its mature structure. A fat pad is an accumulation of adipose tissue. + dph + 2009-05-15T12:42:08Z + biological_process + GO:0060613 + fat pad development + + + + + The progression of a fat pad from its initial formation to its mature structure. A fat pad is an accumulation of adipose tissue. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + The morphogenetic process in which a bud forms from the mammary placode. A mammary bud is bulb of epithelial cells that is distinct from the surrounding epidermis. + dph + 2009-05-18T08:43:14Z + biological_process + GO:0060615 + mammary gland bud formation + + + + + The morphogenetic process in which a bud forms from the mammary placode. A mammary bud is bulb of epithelial cells that is distinct from the surrounding epidermis. + GOC:dph + PMID:12558599 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the mammary gland cord forms by elongation of the mammary bud. The cord is formed once the elongating bud breaks through the mesenchyme and reaches the fat pad. + dph + 2009-05-18T08:57:58Z + mammary gland sprout formation + biological_process + GO:0060616 + mammary gland cord formation + + + + + The process in which the mammary gland cord forms by elongation of the mammary bud. The cord is formed once the elongating bud breaks through the mesenchyme and reaches the fat pad. + GOC:dph + PMID:12558599 + + + + + mammary gland sprout formation + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the nipple over time, from its formation to the mature structure. The nipple is a part of the mammary gland that protrudes from the surface ectoderm. + dph + 2009-05-18T09:29:38Z + biological_process + GO:0060618 + nipple development + + + + + The progression of the nipple over time, from its formation to the mature structure. The nipple is a part of the mammary gland that protrudes from the surface ectoderm. + GOC:dph + + + + + + + + + + + + + + + + + + + + The orderly movement of epithelial cells within the mammary line that contributes to the formation of the mammary placode. + dph + 2009-05-18T09:41:49Z + biological_process + GO:0060619 + cell migration involved in mammary placode formation + + + + + The orderly movement of epithelial cells within the mammary line that contributes to the formation of the mammary placode. + GOC:dph + PMID:12558599 + + + + + + + + + + + + + + + + + + + + + Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell. + dph + 2009-05-18T02:29:43Z + biological_process + GO:0060627 + regulation of vesicle-mediated transport + + + + + Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell. + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + Any process that modulates the rate, frequency, or extent of microtubule-based movement, the movement of organelles, other microtubules and other particles along microtubules, mediated by motor proteins. + dph + 2009-05-18T03:07:02Z + biological_process + GO:0060632 + regulation of microtubule-based movement + + + + + Any process that modulates the rate, frequency, or extent of microtubule-based movement, the movement of organelles, other microtubules and other particles along microtubules, mediated by motor proteins. + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + The process in which a preadipocyte acquires specialized features of a white adipocyte of the mammary gland. White adipocytes have cytoplasmic lipids arranged in a unique vacuole. + dph + 2009-05-27T05:50:56Z + biological_process + GO:0060642 + white fat cell differentiation involved in mammary gland fat development + + + + + The process in which a preadipocyte acquires specialized features of a white adipocyte of the mammary gland. White adipocytes have cytoplasmic lipids arranged in a unique vacuole. + GOC:dph + PMID:12558599 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a cell of the mammary placode becomes a cell of the mammary gland bud. + dph + 2009-05-29T07:58:13Z + biological_process + GO:0060643 + epithelial cell differentiation involved in mammary gland bud morphogenesis + + + + + The process in which a cell of the mammary placode becomes a cell of the mammary gland bud. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland. + dph + 2009-05-29T08:03:07Z + biological_process + GO:0060644 + mammary gland epithelial cell differentiation + + + + + The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland. + GOC:dph + + + + + + + + + + + + + + + + + + + The cell adhesion process in which mammary mesenchyme cells adhere to one another in the initial stages of the formation of mammary fat development. + dph + 2009-05-29T08:33:29Z + biological_process + GO:0060647 + mesenchymal cell condensation involved in mammary fat development + + + + + The cell adhesion process in which mammary mesenchyme cells adhere to one another in the initial stages of the formation of mammary fat development. + GOC:dph + PMID:12558599 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which anatomical structures of the mammary gland buds are generated and organized. Mammary gland buds form by an outpocketing of the mammary placodes and grow to invade the mammary fat, when they form the mammary cord. + dph + 2009-05-29T08:42:22Z + biological_process + GO:0060648 + mammary gland bud morphogenesis + + + + + The process in which anatomical structures of the mammary gland buds are generated and organized. Mammary gland buds form by an outpocketing of the mammary placodes and grow to invade the mammary fat, when they form the mammary cord. + GOC:dph + PMID:12558599 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which anatomical structures of the mammary gland cord are generated and organized. Mammary gland cords form when the mammary gland bud invades the mammary fat. + dph + 2009-05-29T09:06:56Z + mammary gland sprout morphogenesis + biological_process + GO:0060652 + mammary gland cord morphogenesis + + + + + The process in which anatomical structures of the mammary gland cord are generated and organized. Mammary gland cords form when the mammary gland bud invades the mammary fat. + GOC:dph + PMID:12558599 + + + + + mammary gland sprout morphogenesis + GOC:dph + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland cord. Epithelial cells of the mammary cord give it its funnel-like shape and some are cornified. + dph + 2009-05-29T09:17:16Z + biological_process + epithelial cell differentiation involved in mammary gland sprout morphogenesis + GO:0060653 + epithelial cell differentiation involved in mammary gland cord morphogenesis + + + + + The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland cord. Epithelial cells of the mammary cord give it its funnel-like shape and some are cornified. + GOC:dph + PMID:12558599 + + + + + epithelial cell differentiation involved in mammary gland sprout morphogenesis + GOC:dph + + + + + + + + + + + + + + + + + + + The process in which the branching structure of the mammary gland cord is generated and organized. The mammary gland cord is a solid epithelial structure that will hollow out, forming the mammary duct. + dph + 2009-05-29T09:29:32Z + biological_process + GO:0060655 + branching involved in mammary gland cord morphogenesis + + + + + The process in which the branching structure of the mammary gland cord is generated and organized. The mammary gland cord is a solid epithelial structure that will hollow out, forming the mammary duct. + GOC:dph + PMID:12558599 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the nipple is generated and organized. + dph + 2009-05-29T10:45:44Z + biological_process + GO:0060658 + nipple morphogenesis + + + + + The process in which the nipple is generated and organized. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + The developmental process pertaining to the initial formation of the nipple sheath from the unspecified epidermis. This process begins with a circular ingrowth of the epidermis around the region of the mammary sprout. It ends before the region begins to elevate. + dph + 2009-05-29T10:48:39Z + biological_process + GO:0060659 + nipple sheath formation + + + + + The developmental process pertaining to the initial formation of the nipple sheath from the unspecified epidermis. This process begins with a circular ingrowth of the epidermis around the region of the mammary sprout. It ends before the region begins to elevate. + GOC:dph + PMID:12558599 + + + + + + + + + + + + + + + + + + + The process in which the epidermis of the nipple sheath is uplifted to form an umbrella-like projection. + dph + 2009-05-29T11:04:04Z + biological_process + GO:0060660 + epidermis morphogenesis involved in nipple formation + + + + + The process in which the epidermis of the nipple sheath is uplifted to form an umbrella-like projection. + GOC:dph + PMID:12558599 + + + + + + + + + + + + + + + + + + + + + + + + + + + The developmental process pertaining to the initial formation of a submandibular salivary gland. This process begins with a thickening of the epithelium next to the tongue and ends when a bud linked to the oral surface is formed. + dph + 2009-06-01T08:07:16Z + biological_process + GO:0060661 + submandibular salivary gland formation + + + + + The developmental process pertaining to the initial formation of a submandibular salivary gland. This process begins with a thickening of the epithelium next to the tongue and ends when a bud linked to the oral surface is formed. + GOC:dph + PMID:17336109 + + + + + + + + + + + + + + + + + + + The multiplication or reproduction of epithelial cells of the submandibular salivary gland, resulting in the expansion of a cell population and the shaping of the gland. + dph + 2009-06-01T08:36:13Z + biological_process + GO:0060664 + epithelial cell proliferation involved in salivary gland morphogenesis + + + + + The multiplication or reproduction of epithelial cells of the submandibular salivary gland, resulting in the expansion of a cell population and the shaping of the gland. + GOC:dph + PMID:17336109 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the embryonic placenta is generated and organized. + dph + 2009-06-02T09:33:37Z + biological_process + GO:0060669 + embryonic placenta morphogenesis + + + + + The process in which the embryonic placenta is generated and organized. + GOC:dph + + + + + + + + + + + + + + + + + + + + The process in which the branches of the fetal placental villi are generated and organized. The villous part of the placenta is called the labyrinth layer. + dph + 2009-06-02T10:40:40Z + biological_process + GO:0060670 + branching involved in labyrinthine layer morphogenesis + + + + + The process in which the branches of the fetal placental villi are generated and organized. The villous part of the placenta is called the labyrinth layer. + GOC:dph + PMID:16916377 + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a trophoblast cell acquires specialized features of an epithelial cell of the placental labyrinthine layer. + dph + 2009-06-02T11:40:52Z + biological_process + GO:0060671 + epithelial cell differentiation involved in embryonic placenta development + + + + + The process in which a trophoblast cell acquires specialized features of an epithelial cell of the placental labyrinthine layer. + GOC:dph + PMID:16916377 + + + + + + + + + + + + + + + + + + + + + + + + + Any process that mediates the transfer of information from one cell to another. + dph + 2009-06-02T12:58:03Z + cell-cell signalling involved in placenta development + biological_process + GO:0060673 + cell-cell signaling involved in placenta development + + + + + Any process that mediates the transfer of information from one cell to another. + GOC:dph + PMID:16916377 + + + + + cell-cell signalling involved in placenta development + GOC:mah + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a blood vessel of the placenta over time, from its formation to the mature structure. + dph + 2009-06-02T01:09:43Z + biological_process + GO:0060674 + placenta blood vessel development + + + + + The process whose specific outcome is the progression of a blood vessel of the placenta over time, from its formation to the mature structure. + GOC:dph + PMID:16916377 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the ureteric bud is generated and organized. + dph + 2009-06-02T01:31:41Z + biological_process + GO:0060675 + ureteric bud morphogenesis + + + + + The process in which the ureteric bud is generated and organized. + GOC:dph + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct. This process begins when the bud protrudes from the duct and ends when it is a recognizable bud. + dph + 2009-06-02T01:47:23Z + biological_process + GO:0060676 + ureteric bud formation + + + + + The developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct. This process begins when the bud protrudes from the duct and ends when it is a recognizable bud. + GOC:dph + PMID:16916378 + + + + + + + + + + + + + + + The developmental growth in which the ureteric bud grows along its axis beginning with the growth of the primary ureteric bud and ending when the branches of the bud have elongated. + dph + 2009-06-02T02:13:29Z + biological_process + GO:0060677 + ureteric bud elongation + + + + + The developmental growth in which the ureteric bud grows along its axis beginning with the growth of the primary ureteric bud and ending when the branches of the bud have elongated. + GOC:dph + PMID:16916378 + + + + + + + + + + + + + + + + + + + The process in which a branch forms along the side of a ureteric bud. + dph + 2009-06-02T02:44:27Z + biological_process + GO:0060680 + lateral sprouting involved in ureteric bud morphogenesis + + + + + The process in which a branch forms along the side of a ureteric bud. + GOC:dph + PMID:16916378 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the primary ureteric bud grows along its axis dorsally toward the metanephric blastema. + dph + 2009-06-02T02:56:01Z + biological_process + GO:0060682 + primary ureteric bud growth + + + + + The process in which the primary ureteric bud grows along its axis dorsally toward the metanephric blastema. + GOC:dph + PMID:16916378 + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the rate, frequency, or extent of prostatic bud formation, the morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth. + dph + 2009-06-05T12:29:26Z + biological_process + GO:0060685 + regulation of prostatic bud formation + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the rate, frequency, or extent of prostatic bud formation, the morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth. + GOC:dph + + + + + + + + + + + + + + + + + + + Any process that decreases the rate, frequency, or extent of prostatic bud formation, the morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth. + dph + 2009-06-05T12:35:25Z + biological_process + GO:0060686 + negative regulation of prostatic bud formation + + + + + Any process that decreases the rate, frequency, or extent of prostatic bud formation, the morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth. + GOC:dph + + + + + + + + + + + + + + + + + + + Any process that modulates the rate, frequency, or extent of prostate gland branching, the process in which the branching structure of the prostate gland is generated and organized. A branch is a division or offshoot from a main stem. + dph + 2009-06-05T12:37:14Z + biological_process + GO:0060687 + regulation of branching involved in prostate gland morphogenesis + + + + + Any process that modulates the rate, frequency, or extent of prostate gland branching, the process in which the branching structure of the prostate gland is generated and organized. A branch is a division or offshoot from a main stem. + GOC:dph + + + + + + + + + + + + + + + + + + + + + Any process that modulates the rate, frequency, or extent of branching morphogenesis, the process in which the anatomical structures of branches are generated and organized. + dph + 2009-06-05T12:41:44Z + biological_process + GO:0060688 + regulation of morphogenesis of a branching structure + + + + + Any process that modulates the rate, frequency, or extent of branching morphogenesis, the process in which the anatomical structures of branches are generated and organized. + GOC:dph + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize the cells of the salivary gland. + dph + 2009-06-08T01:01:35Z + biological_process + GO:0060689 + cell differentiation involved in salivary gland development + + + + + The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize the cells of the salivary gland. + GOC:dph + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquire specialized structural and/or functional features of an epithelial cell of the salivary gland. + dph + 2009-06-08T01:04:19Z + biological_process + GO:0060690 + epithelial cell differentiation involved in salivary gland development + + + + + The process in which a relatively unspecialized cell acquire specialized structural and/or functional features of an epithelial cell of the salivary gland. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell of the salivary gland to attain its fully functional state. + dph + 2009-06-08T01:06:00Z + biological_process + GO:0060691 + epithelial cell maturation involved in salivary gland development + + + + + The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell of the salivary gland to attain its fully functional state. + GOC:dph + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the salivary gland. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types. + dph + 2009-06-08T01:08:44Z + biological_process + GO:0060692 + mesenchymal cell differentiation involved in salivary gland development + + + + + The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the salivary gland. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types. + GOC:dph + + + + + + + + + + + + + + + + + + + + Any process that modulates the rate, frequency, or extent of branching morphogenesis in the salivary gland epithelium. + dph + 2009-06-08T01:14:44Z + biological_process + GO:0060693 + regulation of branching involved in salivary gland morphogenesis + + + + + Any process that modulates the rate, frequency, or extent of branching morphogenesis in the salivary gland epithelium. + GOC:dph + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize the neurons of the salivary gland. + dph + 2009-06-09T09:35:52Z + biological_process + GO:0060705 + neuron differentiation involved in salivary gland development + + + + + The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize the neurons of the salivary gland. + GOC:dph + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of the embryonic placenta. + dph + 2009-06-09T10:26:42Z + biological_process + GO:0060706 + cell differentiation involved in embryonic placenta development + + + + + The process in which a relatively unspecialized cell acquires specialized features of the embryonic placenta. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell of the ectoplacental cone acquires specialized features of a spongiotrophoblast of the placenta. A spongiotrophoblast cell is a basophilic cell. + dph + 2009-06-09T10:38:10Z + spongiotrophoblast cell differentiation + biological_process + GO:0060708 + spongiotrophoblast differentiation + + + + + The process in which a relatively unspecialized cell of the ectoplacental cone acquires specialized features of a spongiotrophoblast of the placenta. A spongiotrophoblast cell is a basophilic cell. + GOC:dph + PMID:16269175 + + + + + spongiotrophoblast cell differentiation + GOC:cjm + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the labyrinthine layer of the placenta progresses, from its formation to its mature state. + dph + 2009-06-09T03:27:43Z + biological_process + GO:0060711 + labyrinthine layer development + + + + + The process in which the labyrinthine layer of the placenta progresses, from its formation to its mature state. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the spongiotrophoblast layer of the placenta progresses from its formation to its mature state. + dph + 2009-06-09T03:33:40Z + biological_process + GO:0060712 + spongiotrophoblast layer development + + + + + The process in which the spongiotrophoblast layer of the placenta progresses from its formation to its mature state. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the labyrinthine layer of the placenta is generated and organized. + dph + 2009-06-10T08:10:19Z + biological_process + GO:0060713 + labyrinthine layer morphogenesis + + + + + The process in which the labyrinthine layer of the placenta is generated and organized. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + The developmental process pertaining to the initial formation of the labyrinthine layer of the placenta. + dph + 2009-06-10T08:13:14Z + biological_process + GO:0060714 + labyrinthine layer formation + + + + + The developmental process pertaining to the initial formation of the labyrinthine layer of the placenta. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a blood vessel of the labyrinthine layer of the placenta over time, from its formation to the mature structure. The embryonic vessels grow through the layer to come in close contact with the maternal blood supply. + dph + 2009-06-11T09:04:38Z + biological_process + GO:0060716 + labyrinthine layer blood vessel development + + + + + The process whose specific outcome is the progression of a blood vessel of the labyrinthine layer of the placenta over time, from its formation to the mature structure. The embryonic vessels grow through the layer to come in close contact with the maternal blood supply. + GOC:dph + + + + + + + + + + + + + + + + + + + + The biological process whose specific outcome is the progression of a chorion from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The chorion is an extraembryonic membrane. + dph + 2009-06-11T02:37:50Z + biological_process + GO:0060717 + chorion development + + + + + The biological process whose specific outcome is the progression of a chorion from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The chorion is an extraembryonic membrane. + GOC:dph + + + + + + + + + + + + + + + + + + + The multiplication or reproduction of cells, resulting in the expansion of the population in the embryonic placenta. + dph + 2009-06-12T12:46:04Z + biological_process + GO:0060722 + cell proliferation involved in embryonic placenta development + + + + + The multiplication or reproduction of cells, resulting in the expansion of the population in the embryonic placenta. + GOC:dph + + + + + + + + + + + + + + + + + + + Any process that modulates the rate, frequency, or extent of cell proliferation involved in embryonic placenta development. + dph + 2009-06-12T12:50:23Z + biological_process + GO:0060723 + regulation of cell proliferation involved in embryonic placenta development + + + + + Any process that modulates the rate, frequency, or extent of cell proliferation involved in embryonic placenta development. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + The increase in size or mass of the prostate gland where the increase in size or mass has the specific outcome of the progression of the gland, from its formation to its mature state. + dph + 2009-06-15T09:21:52Z + biological_process + GO:0060736 + prostate gland growth + + + + + The increase in size or mass of the prostate gland where the increase in size or mass has the specific outcome of the progression of the gland, from its formation to its mature state. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + The differential increase in size or mass of the prostate gland that contributes to the gland attaining its form. + dph + 2009-06-15T09:24:40Z + prostate gland growth involved in morphogenesis + biological_process + GO:0060737 + prostate gland morphogenetic growth + + + + + The differential increase in size or mass of the prostate gland that contributes to the gland attaining its form. + GOC:dph + + + + + prostate gland growth involved in morphogenesis + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of epithelia of the prostate gland are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube. + dph + 2009-06-16T09:23:22Z + biological_process + GO:0060740 + prostate gland epithelium morphogenesis + + + + + The process in which the anatomical structures of epithelia of the prostate gland are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the prostate gland stroma is generated and organized. The prostate gland stroma is made up of the mesenchymal or fibroblast cells of the prostate gland. + dph + 2009-06-16T09:27:01Z + biological_process + GO:0060741 + prostate gland stromal morphogenesis + + + + + The process in which the prostate gland stroma is generated and organized. The prostate gland stroma is made up of the mesenchymal or fibroblast cells of the prostate gland. + GOC:dph + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell of the prostate gland. + dph + 2009-06-16T09:32:34Z + biological_process + GO:0060742 + epithelial cell differentiation involved in prostate gland development + + + + + The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell of the prostate gland. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell of the prostate gland to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface. + dph + 2009-06-16T09:34:42Z + prostate gland epithelial cell development + biological_process + GO:0060743 + epithelial cell maturation involved in prostate gland development + + + + + The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell of the prostate gland to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface. + GOC:dph + + + + + prostate gland epithelial cell development + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the mammary gland alveolus over time, from its formation to its mature state. The mammary gland alveolus is a sac-like structure that is found in the mature gland. + dph + 2009-06-22T10:52:12Z + biological_process + GO:0060749 + mammary gland alveolus development + + + + + The progression of the mammary gland alveolus over time, from its formation to its mature state. The mammary gland alveolus is a sac-like structure that is found in the mature gland. + GOC:dph + + + + + + + + + + + + + + + + + + + + Any process that modulates the rate, frequency, or extent of branching involved in mammary gland duct morphogenesis. + dph + 2009-06-22T05:20:33Z + biological_process + GO:0060762 + regulation of branching involved in mammary gland duct morphogenesis + + + + + Any process that modulates the rate, frequency, or extent of branching involved in mammary gland duct morphogenesis. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The morphogenetic growth of the large, club-shaped terminal end of a mammary gland duct during prepubertal growth and during puberty. + dph + 2009-07-06T07:33:50Z + biological_process + GO:0060763 + mammary duct terminal end bud growth + + + + + The morphogenetic growth of the large, club-shaped terminal end of a mammary gland duct during prepubertal growth and during puberty. + GOC:dph + PMID:10804170 + + + + + + + + + + + + + + + + + + + + Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mammary gland, from its initial state to the mature structure. + dph + 2009-07-06T09:24:53Z + cell-cell signalling involved in mammary gland development + biological_process + GO:0060764 + cell-cell signaling involved in mammary gland development + + + + + Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mammary gland, from its initial state to the mature structure. + GOC:dph + + + + + cell-cell signalling involved in mammary gland development + GOC:mah + + + + + + + + + + + + + + + + + + + The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the progression of the prostate gland over time. + dph + 2009-07-08T07:32:34Z + biological_process + GO:0060767 + epithelial cell proliferation involved in prostate gland development + + + + + The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the progression of the prostate gland over time. + GOC:dph + + + + + + + + + + + + + + + + + + + Any process that modulates the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time. + dph + 2009-07-08T07:34:56Z + biological_process + GO:0060768 + regulation of epithelial cell proliferation involved in prostate gland development + + + + + Any process that modulates the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + Any process that increases the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time. + dph + 2009-07-08T07:38:02Z + biological_process + GO:0060769 + positive regulation of epithelial cell proliferation involved in prostate gland development + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that increases the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Any process that decreases the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time. + dph + 2009-07-08T07:40:27Z + biological_process + GO:0060770 + negative regulation of epithelial cell proliferation involved in prostate gland development + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that decreases the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time. + GOC:dph + + + + + + + + + + + + + + + + + + + The multiplication or reproduction of mesenchymal cells, resulting in the expansion of a cell population that contributes to the progression of the prostate gland over time. + dph + 2009-07-28T11:50:56Z + biological_process + GO:0060781 + mesenchymal cell proliferation involved in prostate gland development + + + + + The multiplication or reproduction of mesenchymal cells, resulting in the expansion of a cell population that contributes to the progression of the prostate gland over time. + GOC:dph + PMID:12221011 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the prostate gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. + dph + 2009-07-28T11:54:20Z + biological_process + GO:0060782 + regulation of mesenchymal cell proliferation involved in prostate gland development + + + + + Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the prostate gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. + GOC:dph + PMID:12221011 + + + + + + + + + + + + + + + + + + + + + + + + + + + The developmental process in which an ectodermal placode forms. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm. + dph + 2009-08-04T12:15:57Z + biological_process + GO:0060788 + ectodermal placode formation + + + + + The developmental process in which an ectodermal placode forms. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm. + GOC:dph + GOC:sdb_2009 + GOC:tb + + + + + + + + + + + + + + + + + + + + + + + + + + The developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud. + dph + 2009-08-04T12:18:26Z + biological_process + GO:0060789 + hair follicle placode formation + + + + + The developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud. + GOC:dph + GOC:sdb_2009 + GOC:tb + + + + + + + + + + + + + + + + + + + + + + + + + + The developmental process in which the tooth placode forms. A tooth placode is a thickening of the ectoderm that will give rise to the tooth bud. + dph + 2009-08-04T12:21:47Z + biological_process + GO:0060790 + tooth placode formation + + + + + The developmental process in which the tooth placode forms. A tooth placode is a thickening of the ectoderm that will give rise to the tooth bud. + GOC:dph + GOC:sdb_2009 + GOC:tb + + + + + + + + + + + + + + + + + + + + + + + + + + The developmental process in which a sebaceous gland placode forms. A sebaceous gland placode is a thickening of the ectoderm that will give rise to the sebaceous gland bud. + dph + 2009-08-04T12:23:09Z + biological_process + GO:0060791 + sebaceous gland placode formation + + + + + The developmental process in which a sebaceous gland placode forms. A sebaceous gland placode is a thickening of the ectoderm that will give rise to the sebaceous gland bud. + GOC:dph + GOC:sdb_2009 + GOC:tb + + + + + + + + + + + + + + + + + + + + The progression of the sweat gland over time, from its formation to the mature structure. Sweat glands secrete an aqueous solution that is used in thermoregulation. + dph + 2009-08-04T12:35:12Z + biological_process + GO:0060792 + sweat gland development + + + + + The progression of the sweat gland over time, from its formation to the mature structure. Sweat glands secrete an aqueous solution that is used in thermoregulation. + GOC:dph + GOC:sdb_2009 + GOC:tb + + + + + + + + + + + + + + + + + + + + + + + + + + The developmental process in which the sweat gland placode forms. An sweat gland placode is a thickening of the ectoderm that will give rise to the sweat gland bud. + dph + 2009-08-04T12:38:10Z + biological_process + GO:0060793 + sweat gland placode formation + + + + + The developmental process in which the sweat gland placode forms. An sweat gland placode is a thickening of the ectoderm that will give rise to the sweat gland bud. + GOC:dph + GOC:sdb_2009 + GOC:tb + + + + + + + + + + + + + + + + + + + The commitment of cells to specific cell fates of the endoderm, ectoderm, or mesoderm as a part of gastrulation. + dph + 2009-08-04T03:11:22Z + biological_process + GO:0060795 + cell fate commitment involved in formation of primary germ layer + + + + + The commitment of cells to specific cell fates of the endoderm, ectoderm, or mesoderm as a part of gastrulation. + GOC:dph + GOC:sdb_2009 + GOC:tb + + + + + + + + + + + + + + + + + + + Any process that modulates the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state. + dph + 2009-08-06T01:20:25Z + biological_process + GO:0060800 + regulation of cell differentiation involved in embryonic placenta development + + + + + Any process that modulates the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state. + GOC:dph + GOC:sdb_2009 + GOC:tb + + + + + + + + + + + + + + + + + + + Any process that decreases the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state. + dph + 2009-08-06T02:02:18Z + biological_process + GO:0060806 + negative regulation of cell differentiation involved in embryonic placenta development + + + + + Any process that decreases the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state. + GOC:dph + GOC:sdb_2009 + GOC:tb + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a venous blood vessel endothelial cell acquires specialized features of a lymphatic vessel endothelial cell, a thin flattened cell that lines the inside surfaces of lymph vessels. + dph + 2009-08-11T03:45:20Z + biological_process + GO:0060836 + lymphatic endothelial cell differentiation + + + + + The process in which a venous blood vessel endothelial cell acquires specialized features of a lymphatic vessel endothelial cell, a thin flattened cell that lines the inside surfaces of lymph vessels. + GOC:dph + GOC:sdb_2009 + GOC:tb + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell, a thin flattened cell that lines the inside surfaces of blood vessels. + dph + 2009-08-11T03:47:36Z + biological_process + GO:0060837 + blood vessel endothelial cell differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell, a thin flattened cell that lines the inside surfaces of blood vessels. + GOC:dph + GOC:sdb_2009 + GOC:tb + + + + + + + + + + + + + + + + + + + + The progression of the artery over time, from its initial formation to the mature structure. An artery is a blood vessel that carries blood away from the heart to a capillary bed. + dph + 2009-08-12T10:10:51Z + biological_process + GO:0060840 + artery development + + + + + The progression of the artery over time, from its initial formation to the mature structure. An artery is a blood vessel that carries blood away from the heart to a capillary bed. + GOC:dph + GOC:sdb_2009 + GOC:tb + + + + + + + + + + + + + + + + + + + + The progression of the venous blood vessel over time from its initial formation to the mature structure. Venous blood vessels carry blood back to the heart after the capillary bed. + dph + 2009-08-12T10:14:07Z + biological_process + GO:0060841 + venous blood vessel development + + + + + The progression of the venous blood vessel over time from its initial formation to the mature structure. Venous blood vessels carry blood back to the heart after the capillary bed. + GOC:dph + GOC:sdb_2009 + GOC:tb + + + + + + + + + + + + + + + + + + + + + + + + + + The process of the coordinated growth and sprouting of lymph vessels giving rise to the organized lymphatic system. + dph + 2009-08-12T12:00:48Z + patterning of lymph vessels + biological_process + GO:0060854 + branching involved in lymph vessel morphogenesis + + + + + The process of the coordinated growth and sprouting of lymph vessels giving rise to the organized lymphatic system. + GOC:dph + GOC:sdb_2009 + GOC:tb + + + + + patterning of lymph vessels + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the semicircular canal from its initial formation to the mature structure. + dph + 2009-08-13T09:36:37Z + biological_process + GO:0060872 + semicircular canal development + + + + + The progression of the semicircular canal from its initial formation to the mature structure. + GOC:dph + GOC:sdb_2009 + GOC:tb + + + + + + + + + + + + + + + + + + + + The progession of the anterior semicircular canal from its initial formation to the mature structure. + dph + 2009-08-13T09:39:49Z + biological_process + GO:0060873 + anterior semicircular canal development + + + + + The progession of the anterior semicircular canal from its initial formation to the mature structure. + GOC:dph + GOC:sdb_2009 + GOC:tb + + + + + + + + + + + + + + + + + + + + The progession of the posterior semicircular canal from its initial formation to the mature structure. + dph + 2009-08-13T09:42:39Z + biological_process + GO:0060874 + posterior semicircular canal development + + + + + The progession of the posterior semicircular canal from its initial formation to the mature structure. + GOC:dph + GOC:sdb_2009 + GOC:tb + + + + + + + + + + + + + + + + + + + + The progession of the lateral semicircular canal from its initial formation to the mature structure. + dph + 2009-08-13T09:43:25Z + biological_process + GO:0060875 + lateral semicircular canal development + + + + + The progession of the lateral semicircular canal from its initial formation to the mature structure. + GOC:dph + GOC:sdb_2009 + GOC:tb + + + + + + + + + + + + + + + + + + + + + + + + + + + The developmental process pertaining to the initial formation of the semicircular canal from the otic vesicle. This process begins with the regionalization of the vesicle that specifies the area where the vesicles will form and continues through the process of fusion which forms the initial tubes. + dph + 2009-08-13T09:45:07Z + biological_process + GO:0060876 + semicircular canal formation + + + + + The developmental process pertaining to the initial formation of the semicircular canal from the otic vesicle. This process begins with the regionalization of the vesicle that specifies the area where the vesicles will form and continues through the process of fusion which forms the initial tubes. + GOC:dph + GOC:sdb_2009 + GOC:tb + + + + + + + + + + + + + + + + + + + The pattern specification process that results in the subdivision of the otic epithelium in space to define an area or volume in which cells will differentiate to give rise to the semicircular canals. + dph + 2009-08-13T09:56:45Z + biological_process + GO:0060877 + regionalization involved in semicircular canal formation + + + + + The pattern specification process that results in the subdivision of the otic epithelium in space to define an area or volume in which cells will differentiate to give rise to the semicircular canals. + GOC:dph + GOC:sdb_2009 + GOC:tb + + + + + + + + + + + + + + + + + + + + + The morphogenetic process in which an epithelial sheet bends along a linear axis and gives rise to a pouch that will form a semicircular canal. + dph + 2009-08-13T10:01:01Z + biological_process + GO:0060878 + pouch outgrowth involved in semicircular canal formation + + + + + The morphogenetic process in which an epithelial sheet bends along a linear axis and gives rise to a pouch that will form a semicircular canal. + GOC:dph + GOC:sdb_2009 + GOC:tb + + + + + + + + + + + + + + + + + + + + + + + + + + Creation of the central hole of the semicircular canal by sealing the edges of the pouch that forms during the process of semicircular canal formation. + dph + 2009-08-13T10:05:51Z + biological_process + GO:0060879 + semicircular canal fusion + + + + + Creation of the central hole of the semicircular canal by sealing the edges of the pouch that forms during the process of semicircular canal formation. + GOC:dph + GOC:sdb_2009 + GOC:tb + + + + + + + + + + + + + + + + + + + + + The change in form (cell shape and size) that occurs when a semicircular canal epithelial cell acquires the structural features that allow it to contribute to the process of semicircular canal fusion. + dph + 2009-08-13T10:13:25Z + biological_process + GO:0060880 + cell morphogenesis involved in semicircular canal fusion + + + + + The change in form (cell shape and size) that occurs when a semicircular canal epithelial cell acquires the structural features that allow it to contribute to the process of semicircular canal fusion. + GOC:dph + GOC:sdb_2009 + GOC:tb + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the epidermis of the limb over time, from its formation to the mature structure. The limb epidermis is the outer epithelial layer of the limb, it is a complex stratified squamous epithelium. + dph + 2009-08-13T12:39:39Z + biological_process + GO:0060887 + limb epidermis development + + + + + The process whose specific outcome is the progression of the epidermis of the limb over time, from its formation to the mature structure. The limb epidermis is the outer epithelial layer of the limb, it is a complex stratified squamous epithelium. + GOC:dph + GOC:sdb_2009 + GOC:tb + + + + + + + + + The developmental process that results in the creation of defined areas or spaces within the neural plate to which cells respond and eventually are instructed to differentiate. + dph + 2009-08-13T02:06:27Z + biological_process + GO:0060896 + neural plate pattern specification + + + + + The developmental process that results in the creation of defined areas or spaces within the neural plate to which cells respond and eventually are instructed to differentiate. + GOC:dph + GOC:sdb_2009 + GOC:tb + + + + + + + + + + The pattern specification process that results in the subdivision of an axis or axes of the neural plate in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment. + dph + 2009-08-13T02:09:04Z + biological_process + GO:0060897 + neural plate regionalization + + + + + The pattern specification process that results in the subdivision of an axis or axes of the neural plate in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment. + GOC:dph + GOC:sdb_2009 + GOC:tb + + + + + + + + + + + + + + + + The developmental process pertaining to the initial formation of a camera-type eye from unspecified neurectoderm. This process begins with the differentiation of cells that form the optic field and ends when the optic cup has attained its shape. + dph + 2009-08-13T02:26:54Z + biological_process + GO:0060900 + embryonic camera-type eye formation + + + + + The developmental process pertaining to the initial formation of a camera-type eye from unspecified neurectoderm. This process begins with the differentiation of cells that form the optic field and ends when the optic cup has attained its shape. + GOC:dph + GOC:sdb_2009 + GOC:tb + + + + + + + + + + + + + + + + + + + + + + + + + + The developmental process pertaining to the initial formation of the heart from unspecified parts. This process begins with the specific processes that contribute to the appearance of the heart field and the arrival of cardiac neural crest to the heart region. The process ends when the structural rudiment is recognizable. + dph + 2009-09-17T09:02:13Z + biological_process + cardiogenesis + GO:0060914 + heart formation + + + + + The developmental process pertaining to the initial formation of the heart from unspecified parts. This process begins with the specific processes that contribute to the appearance of the heart field and the arrival of cardiac neural crest to the heart region. The process ends when the structural rudiment is recognizable. + GOC:mtg_heart + + + + + cardiogenesis + GOC:mtg_heart + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the lung. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types. + dph + 2009-09-18T11:45:33Z + biological_process + GO:0060915 + mesenchymal cell differentiation involved in lung development + + + + + The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the lung. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types. + GOC:dph + + + + + + + + + + + + + + + + + + + The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population that contributes to the progression of the lung over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. + dph + 2009-09-18T11:50:17Z + biological_process + GO:0060916 + mesenchymal cell proliferation involved in lung development + + + + + The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population that contributes to the progression of the lung over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. + GOC:dph + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of a pacemaker cell. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions. + dph + 2009-09-29T11:01:31Z + pacemaker cell differentiation + biological_process + GO:0060920 + cardiac pacemaker cell differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized features of a pacemaker cell. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions. + GOC:mtg_cardiac_conduct_nov11 + GOC:mtg_heart + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of a sinoatrial (SA) node cell. SA node cells are pacemaker cells that are found in the sinoatrial node. + dph + 2009-09-29T11:03:30Z + SA node cell differentiation + SAN cell differentiation + sinus node cell differentiation + biological_process + GO:0060921 + sinoatrial node cell differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized features of a sinoatrial (SA) node cell. SA node cells are pacemaker cells that are found in the sinoatrial node. + GOC:mtg_heart + + + + + SA node cell differentiation + GOC:mtg_heart + + + + + SAN cell differentiation + GOC:BHF + GOC:mtg_cardiac_conduct_nov11 + + + + + sinus node cell differentiation + GOC:BHF + GOC:mtg_cardiac_conduct_nov11 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of an atrioventricular (AV) node cell. AV node cells are pacemaker cells that are found in the atrioventricular node. + dph + 2009-09-29T11:07:06Z + biological_process + AV node cell differentiation + GO:0060922 + atrioventricular node cell differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized features of an atrioventricular (AV) node cell. AV node cells are pacemaker cells that are found in the atrioventricular node. + GOC:mtg_heart + + + + + AV node cell differentiation + GOC:mtg_heart + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a pacemaker cell over time, from its formation to the mature state. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions. + dph + 2009-09-29T11:51:55Z + pacemaker cell development + biological_process + GO:0060926 + cardiac pacemaker cell development + + + + + The process whose specific outcome is the progression of a pacemaker cell over time, from its formation to the mature state. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions. + GOC:mtg_cardiac_conduct_nov11 + GOC:mtg_heart + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of an atrioventricular (AV) node cell over time, from its formation to the mature state. + dph + 2009-09-29T11:59:26Z + AV node cell development + biological_process + GO:0060928 + atrioventricular node cell development + + + + + The process whose specific outcome is the progression of an atrioventricular (AV) node cell over time, from its formation to the mature state. + GOC:mtg_heart + + + + + AV node cell development + GOC:mtg_heart + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a sinoatrial (SA) node cell over time, from its formation to the mature state. SA node cells are pacemaker cells that are found in the sinoatrial node. + dph + 2009-09-29T12:05:47Z + SA node cell development + SAN cell development + sinus node cell development + biological_process + GO:0060931 + sinoatrial node cell development + + + + + The process whose specific outcome is the progression of a sinoatrial (SA) node cell over time, from its formation to the mature state. SA node cells are pacemaker cells that are found in the sinoatrial node. + GOC:mtg_heart + + + + + SA node cell development + GOC:mtg_heart + + + + + SAN cell development + GOC:BHF + GOC:mtg_cardiac_conduct_nov11 + + + + + sinus node cell development + GOC:BHF + GOC:mtg_cardiac_conduct_nov11 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the His-Purkinje system. These cells form the fibers regulate cardiac muscle contraction in the ventricles. + dph + 2009-09-29T01:10:32Z + biological_process + GO:0060932 + His-Purkinje system cell differentiation + + + + + The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the His-Purkinje system. These cells form the fibers regulate cardiac muscle contraction in the ventricles. + GOC:mtg_heart + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a His-Purkinje cell over time, from its formation to the mature state. These cells form the fibers that regulate cardiac muscle contraction in the ventricles. + dph + 2009-09-29T01:15:02Z + biological_process + GO:0060933 + His-Purkinje system cell development + + + + + The process whose specific outcome is the progression of a His-Purkinje cell over time, from its formation to the mature state. These cells form the fibers that regulate cardiac muscle contraction in the ventricles. + GOC:mtg_heart + + + + + + + + + + + + + + + + + + + The orderly movement of a cell from one site to another that will contribute to the progression of the heart over time, from its initial formation, to the mature organ. + dph + 2009-10-06T10:53:49Z + biological_process + GO:0060973 + cell migration involved in heart development + + + + + The orderly movement of a cell from one site to another that will contribute to the progression of the heart over time, from its initial formation, to the mature organ. + GOC:mtg_heart + + + + + + + + + + + + + + + + + + + The orderly movement of a cell from one site to another that contribute to the formation of the heart. The initial heart structure is made up of mesoderm-derived heart progenitor cells and neural crest-derived cells. + dph + 2009-10-06T10:56:33Z + biological_process + GO:0060974 + cell migration involved in heart formation + + + + + The orderly movement of a cell from one site to another that contribute to the formation of the heart. The initial heart structure is made up of mesoderm-derived heart progenitor cells and neural crest-derived cells. + GOC:mtg_heart + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the blood vessels of the heart over time, from its formation to the mature structure. + dph + 2009-10-06T12:15:23Z + cardiac blood vessel development + cardiac vasculature development + coronary blood vessel development + heart blood vessel development + heart vasculature development + biological_process + GO:0060976 + coronary vasculature development + + + + + The process whose specific outcome is the progression of the blood vessels of the heart over time, from its formation to the mature structure. + GOC:mtg_heart + + + + + cardiac blood vessel development + GOC:mtg_heart + + + + + cardiac vasculature development + GOC:mtg_heart + + + + + coronary blood vessel development + GOC:mtg_heart + + + + + heart blood vessel development + GOC:mtg_heart + + + + + heart vasculature development + GOC:mtg_heart + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of blood vessels of the heart are generated and organized. The blood vessel is the vasculature carrying blood. + dph + 2009-10-06T12:28:23Z + cardiac blood vessel morphogenesis + cardiac vasculature morphogenesis + coronary blood vessel morphogenesis + heart blood vessel morphogenesis + heart vasculature morphogenesis + biological_process + GO:0060977 + coronary vasculature morphogenesis + + + + + The process in which the anatomical structures of blood vessels of the heart are generated and organized. The blood vessel is the vasculature carrying blood. + GOC:mtg_heart + + + + + cardiac blood vessel morphogenesis + GOC:mtg_heart + + + + + cardiac vasculature morphogenesis + GOC:mtg_heart + + + + + coronary blood vessel morphogenesis + GOC:mtg_heart + + + + + heart blood vessel morphogenesis + GOC:mtg_heart + + + + + heart vasculature morphogenesis + GOC:mtg_heart + + + + + + + + + + + + + + + + + + + + + + + + + Blood vessel formation in the heart when new vessels emerge from the proliferation of pre-existing blood vessels. + dph + 2009-10-06T02:02:12Z + angiogenesis involved in cardiac vascular morphogenesis + angiogenesis involved in heart vascular morphogenesis + coronary blood vessel angiogenesis + coronary vasculature angiogenesis + biological_process + GO:0060978 + angiogenesis involved in coronary vascular morphogenesis + + + + + Blood vessel formation in the heart when new vessels emerge from the proliferation of pre-existing blood vessels. + GOC:mtg_heart + + + + + angiogenesis involved in cardiac vascular morphogenesis + GOC:mtg_heart + + + + + angiogenesis involved in heart vascular morphogenesis + GOC:mtg_heart + + + + + coronary blood vessel angiogenesis + GOC:mtg_heart + + + + + coronary vasculature angiogenesis + GOC:mtg_heart + + + + + + + + + + + + + + + + + + + The differentiation of endothelial cells from progenitor cells that contributes to blood vessel development in the heart, and the de novo formation of blood vessels and tubes. + dph + 2009-10-06T02:19:42Z + coronary vasculogenesis + vasculogenesis involved in coronary blood vessel morphogenesis + biological_process + GO:0060979 + vasculogenesis involved in coronary vascular morphogenesis + + + + + The differentiation of endothelial cells from progenitor cells that contributes to blood vessel development in the heart, and the de novo formation of blood vessels and tubes. + GOC:mtg_heart + + + + + coronary vasculogenesis + GOC:mtg_heart + + + + + vasculogenesis involved in coronary blood vessel morphogenesis + GOC:mtg_heart + + + + + + + + + + + + + + + + + + + The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form the blood vessels of the heart. + dph + 2009-10-06T02:33:06Z + biological_process + GO:0060980 + cell migration involved in coronary vasculogenesis + + + + + The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form the blood vessels of the heart. + GOC:mtg_heart + + + + + + + + + + + + + + + + + + + The orderly movement of a cell from one site to another that will contribute to the formation of new blood vessels in the heart from pre-existing blood vessels. + dph + 2009-10-06T02:49:12Z + biological_process + GO:0060981 + cell migration involved in coronary angiogenesis + + + + + The orderly movement of a cell from one site to another that will contribute to the formation of new blood vessels in the heart from pre-existing blood vessels. + GOC:mtg_heart + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of coronary arteries are generated and organized. Coronary arteries are blood vessels that transport blood to the heart muscle. + dph + 2009-10-06T02:58:52Z + biological_process + GO:0060982 + coronary artery morphogenesis + + + + + The process in which the anatomical structures of coronary arteries are generated and organized. Coronary arteries are blood vessels that transport blood to the heart muscle. + GOC:mtg_heart + + + + + + + + + + + + + + + The regulated release of a hormone into the circulatory system. + dph + 2010-01-11T09:03:48Z + biological_process + GO:0060986 + endocrine hormone secretion + + + + + The regulated release of a hormone into the circulatory system. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + Morphogenesis of a kidney. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. + dph + 2010-01-19T08:16:55Z + biological_process + GO:0060993 + kidney morphogenesis + + + + + Morphogenesis of a kidney. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. + GOC:dph + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + Any process that mediates the transfer of information from one cell to another and contributes to the progression of the kidney over time, from its formation to the mature organ. + dph + 2010-01-19T08:33:40Z + cell-cell signalling involved in kidney development + biological_process + GO:0060995 + cell-cell signaling involved in kidney development + + + + + Any process that mediates the transfer of information from one cell to another and contributes to the progression of the kidney over time, from its formation to the mature organ. + GOC:dph + GOC:mtg_kidney_jan10 + + + + + cell-cell signalling involved in kidney development + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + Any developmental process that results in the creation of defined areas or spaces within the kidney to which cells respond and eventually are instructed to differentiate. + dph + 2010-01-21T09:05:54Z + kidney pattern specification + biological_process + kidney pattern formation + pattern formation involved in kidney development + GO:0061004 + pattern specification involved in kidney development + + + + + Any developmental process that results in the creation of defined areas or spaces within the kidney to which cells respond and eventually are instructed to differentiate. + GOC:dph + GOC:mtg_kidney_jan10 + + + + + kidney pattern specification + GOC:mtg_kidney_jan10 + + + + + kidney pattern formation + GOC:mtg_kidney_jan10 + + + + + pattern formation involved in kidney development + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the kidney as it progresses from its formation to the mature state. + dph + 2010-01-21T09:13:55Z + biological_process + GO:0061005 + cell differentiation involved in kidney development + + + + + The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the kidney as it progresses from its formation to the mature state. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of cell proliferation that contributes to the shaping of the kidney. + dph + 2010-01-21T11:25:23Z + biological_process + GO:0061006 + regulation of cell proliferation involved in kidney morphogenesis + + + + + Any process that modulates the frequency, rate or extent of cell proliferation that contributes to the shaping of the kidney. + GOC:dph + GOC:mtg_kidney_jan10 + + + + + + + + + An system process carried out by any of the organs or tissues of the hepaticobiliary system. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins. + dph + 2010-01-22T09:09:10Z + hepatobiliary system process + biological_process + GO:0061007 + + hepaticobiliary system process + + + + + An system process carried out by any of the organs or tissues of the hepaticobiliary system. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins. + GOC:dph + + + + + hepatobiliary system process + GOC:dph + + + + + + + + + + + + + + + + + + + + The progression of the hepaticobiliary system over time, from its formation to the mature structure. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins. + dph + 2010-01-22T09:11:59Z + hepatobiliary system development + biological_process + GO:0061008 + hepaticobiliary system development + + + + + The progression of the hepaticobiliary system over time, from its formation to the mature structure. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins. + GOC:dph + + + + + hepatobiliary system development + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the common bile duct over time, from its formation to the mature structure. The common bile duct is formed from the joining of the common hepatic duct running from the liver, and the cystic duct running from the gall bladder. The common bile duct transports bile from the liver and gall bladder to the intestine. + dph + 2010-01-22T09:17:13Z + EHBD development + extrahepatic bile duct development + CBD development + bile duct development + biological_process + GO:0061009 + common bile duct development + + + + + The progression of the common bile duct over time, from its formation to the mature structure. The common bile duct is formed from the joining of the common hepatic duct running from the liver, and the cystic duct running from the gall bladder. The common bile duct transports bile from the liver and gall bladder to the intestine. + PMID:20614624 + + + + + EHBD development + PMID:20614624 + + + + + extrahepatic bile duct development + PMID:20614624 + + + + + CBD development + PMID:20614624 + + + + + bile duct development + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the gall bladder over time, from its initial formation to the mature structure. The gall bladder is a cavitated organ that stores bile. + dph + 2010-01-22T09:38:44Z + biological_process + GO:0061010 + gall bladder development + + + + + The progression of the gall bladder over time, from its initial formation to the mature structure. The gall bladder is a cavitated organ that stores bile. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the hepatic duct over time, from its formation to the mature structure. The hepatic duct is the duct that leads from the liver to the common bile duct. + dph + 2010-01-22T09:44:39Z + biological_process + GO:0061011 + hepatic duct development + + + + + The progression of the hepatic duct over time, from its formation to the mature structure. The hepatic duct is the duct that leads from the liver to the common bile duct. + GOC:dph + PMID:20614624 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of a hepatoblast. A hepatoblast is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into hepatocytes and cholangiocytes. + dph + 2010-02-02T09:08:03Z + biological_process + GO:0061017 + hepatoblast differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized features of a hepatoblast. A hepatoblast is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into hepatocytes and cholangiocytes. + GOC:dph + PMID:15226394 + + + + + + + + + + + + + + + + + + + + A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins. + jl + 2010-02-08T02:43:11Z + GO:0016044 + GO:0044802 + cellular membrane organisation + cellular membrane organization + membrane organisation + biological_process + membrane organization and biogenesis + single-organism membrane organization + GO:0061024 + + + + + + + membrane organization + + + + + A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins. + GOC:dph + GOC:tb + + + + + membrane organisation + GOC:mah + + + + + membrane organization and biogenesis + GOC:mah + + + + + + + + + + + + + + + + + + + + The membrane organization process that joins two lipid bilayers to form a single membrane. + jl + 2010-02-08T02:48:06Z + GO:0006944 + GO:0044801 + Wikipedia:Lipid_bilayer_fusion + cellular membrane fusion + biological_process + single-organism membrane fusion + GO:0061025 + + membrane fusion + + + + + The membrane organization process that joins two lipid bilayers to form a single membrane. + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the development of the umbilical cord, from its formation to the mature structure. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta. + dph + 2010-02-09T09:09:22Z + biological_process + GO:0061027 + umbilical cord development + + + + + The process whose specific outcome is the development of the umbilical cord, from its formation to the mature structure. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta. + GOC:BHF + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the eyelid in a camera-type eye from its formation to the mature state. The eyelid is a membranous cover that helps protect and lubricate the eye. + dph + 2010-02-09T09:36:11Z + biological_process + GO:0061029 + eyelid development in camera-type eye + + + + + The progression of the eyelid in a camera-type eye from its formation to the mature state. The eyelid is a membranous cover that helps protect and lubricate the eye. + GOC:dph + GOC:yaf + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland alveolus. + dph + 2010-02-09T09:43:00Z + biological_process + GO:0061030 + epithelial cell differentiation involved in mammary gland alveolus development + + + + + The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland alveolus. + GOC:dph + GOC:yaf + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the visceral serous pericardium from its formation to the mature structure. The visceral serous pericardium is the inner layer of the pericardium. + dph + 2010-02-09T09:52:49Z + epicardium development + biological_process + GO:0061032 + visceral serous pericardium development + + + + + The progression of the visceral serous pericardium from its formation to the mature structure. The visceral serous pericardium is the inner layer of the pericardium. + GOC:dph + GOC:yaf + + + + + epicardium development + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the olfactory bulb mitral cell layer over time from its initial formation until its mature state. The mitral cell layer is composed of pyramidal neurons whose cell bodies are located between the granule cell layer and the plexiform layer. + dph + 2010-02-09T03:30:23Z + biological_process + GO:0061034 + olfactory bulb mitral cell layer development + + + + + The progression of the olfactory bulb mitral cell layer over time from its initial formation until its mature state. The mitral cell layer is composed of pyramidal neurons whose cell bodies are located between the granule cell layer and the plexiform layer. + GOC:dph + + + + + + + + + + + + + + + + + + + + Any process that modulates the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. + dph + 2010-02-09T03:41:35Z + biological_process + GO:0061035 + regulation of cartilage development + + + + + Any process that modulates the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + Any process that increases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. + dph + 2010-02-09T03:41:35Z + biological_process + GO:0061036 + positive regulation of cartilage development + + + + + Any process that increases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + Any process that decreases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. + dph + 2010-02-09T03:41:35Z + biological_process + GO:0061037 + negative regulation of cartilage development + + + + + Any process that decreases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which anatomical structures of the uterus are generated and organized. + dph + 2010-02-22T11:12:35Z + biological_process + GO:0061038 + uterus morphogenesis + + + + + The process in which anatomical structures of the uterus are generated and organized. + GOC:BHF + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a female gonad is generated and organized. + dph + 2010-02-22T11:29:28Z + biological_process + ovary morphogenesis + GO:0061040 + female gonad morphogenesis + + + + + The process in which a female gonad is generated and organized. + GOC:BHF + GOC:dph + + + + + ovary morphogenesis + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + Any process that modulates the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury. + dph + 2010-02-25T10:14:37Z + biological_process + GO:0061041 + regulation of wound healing + + + + + Any process that modulates the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury. + GOC:BHF + GOC:dph + + + + + + + + + + + + + + + + + + + + + + Any process that decreases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury. + dph + 2010-02-25T10:33:30Z + biological_process + GO:0061045 + negative regulation of wound healing + + + + + Any process that decreases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury. + GOC:dph + + + + + + + + + + + + + + + + + + + Any process that modulates the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units. + dph + 2010-02-25T10:41:38Z + biological_process + GO:0061046 + regulation of branching involved in lung morphogenesis + + + + + Any process that modulates the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units. + GOC:dph + GOC:yaf + + + + + + + + + + + + + + + + + + + Any process that increases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units. + dph + 2010-02-25T10:50:01Z + biological_process + GO:0061047 + positive regulation of branching involved in lung morphogenesis + + + + + Any process that increases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units. + GOC:dph + GOC:yaf + + + + + + + + + + + + + + + + + + + Any process that decreases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units. + dph + 2010-02-25T10:51:31Z + biological_process + GO:0061048 + negative regulation of branching involved in lung morphogenesis + + + + + Any process that decreases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units. + GOC:dph + GOC:yaf + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state. + dph + 2010-02-25T12:56:07Z + biological_process + cardiac muscle cell hypertrophy + cardiomyocyte growth + heart muscle cell growth + GO:0061049 + cell growth involved in cardiac muscle cell development + + + + + The growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state. + GOC:dph + + + + + cardiac muscle cell hypertrophy + GOC:dph + + + + + cardiomyocyte growth + GOC:dph + + + + + heart muscle cell growth + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state. + dph + 2010-02-25T01:05:16Z + biological_process + GO:0061050 + regulation of cell growth involved in cardiac muscle cell development + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + Any process that increases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state. + dph + 2010-02-25T01:08:08Z + biological_process + GO:0061051 + positive regulation of cell growth involved in cardiac muscle cell development + + + + + Any process that increases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + Any process that decreases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state. + dph + 2010-02-25T01:11:30Z + biological_process + GO:0061052 + negative regulation of cell growth involved in cardiac muscle cell development + + + + + Any process that decreases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of a somite from its initial formation to the mature structure. Somites are mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo. + dph + 2010-03-02T12:05:13Z + biological_process + GO:0061053 + somite development + + + + + The progression of a somite from its initial formation to the mature structure. Somites are mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin. + dph + 2010-03-02T12:07:37Z + biological_process + GO:0061054 + dermatome development + + + + + The progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the myotome over time, from its formation to the mature structure. The myotome is the portion of the somite that will give rise to muscle. + dph + 2010-03-02T12:11:01Z + biological_process + GO:0061055 + myotome development + + + + + The progression of the myotome over time, from its formation to the mature structure. The myotome is the portion of the somite that will give rise to muscle. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra. + dph + 2010-03-02T12:12:40Z + biological_process + GO:0061056 + sclerotome development + + + + + The progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of a muscle structure over time, from its formation to its mature state. Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms. + dph + 2010-03-09T08:55:14Z + biological_process + GO:0061061 + + muscle structure development + + + + + The progression of a muscle structure over time, from its formation to its mature state. Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms. + GOC:dph + + + + + + + + + + + + + + + + + + + + Any process that modulates the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew. + dph + 2010-03-11T12:59:21Z + biological_process + GO:0061062 + regulation of nematode larval development + + + + + Any process that modulates the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew. + GOC:dph + GOC:kmv + + + + + + + + + + + + + + + + + + + + + Any process that increases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew. + dph + 2010-03-11T01:03:34Z + biological_process + GO:0061063 + positive regulation of nematode larval development + + + + + Any process that increases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew. + GOC:dph + GOC:kmv + + + + + + + + + + + + + + + + + + + + + Any process that decreases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew. + dph + 2010-03-11T01:04:39Z + biological_process + GO:0061064 + negative regulation of nematode larval development + + + + + Any process that decreases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew. + GOC:dph + GOC:kmv + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the urethra over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body. + dph + 2010-03-12T08:24:52Z + biological_process + GO:0061068 + urethra development + + + + + The progression of the urethra over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body. + GOC:dph + + + + + + + + + + + + + + + + + + + + The progression of the male urethra over time from its initial formation to the mature structure. The male urethra is a renal system organ that carries urine from the bladder through the penis to outside the body. + dph + 2010-03-12T08:28:19Z + biological_process + GO:0061069 + male urethra development + + + + + The progression of the male urethra over time from its initial formation to the mature structure. The male urethra is a renal system organ that carries urine from the bladder through the penis to outside the body. + GOC:dph + + + + + + + + + + + + + + + + + + + + The progression of the female urethra over time from its initial formation to the mature structure. The female urethra is a renal system organ that carries urine from the bladder to outside the body, exiting above the vaginal opening. + dph + 2010-03-12T08:29:43Z + biological_process + GO:0061070 + female urethra development + + + + + The progression of the female urethra over time from its initial formation to the mature structure. The female urethra is a renal system organ that carries urine from the bladder to outside the body, exiting above the vaginal opening. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the urethra epithelium over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body. The epithelium is the tubular, planar layer of cells through which the urine passes. + dph + 2010-03-12T08:36:53Z + biological_process + GO:0061071 + urethra epithelium development + + + + + The progression of the urethra epithelium over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body. The epithelium is the tubular, planar layer of cells through which the urine passes. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the iris is generated and organized. The iris is an anatomical structure in the eye whose opening forms the pupil. The iris is responsible for controlling the diameter and size of the pupil and the amount of light reaching the retina. + dph + 2010-03-16T10:48:42Z + biological_process + GO:0061072 + iris morphogenesis + + + + + The process in which the iris is generated and organized. The iris is an anatomical structure in the eye whose opening forms the pupil. The iris is responsible for controlling the diameter and size of the pupil and the amount of light reaching the retina. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the ciliary body generated and organized. The ciliary body is the circumferential tissue inside the eye composed of the ciliary muscle and ciliary processes. + dph + 2010-03-16T10:55:19Z + biological_process + GO:0061073 + ciliary body morphogenesis + + + + + The process in which the ciliary body generated and organized. The ciliary body is the circumferential tissue inside the eye composed of the ciliary muscle and ciliary processes. + GOC:dph + + + + + + + + + + + + + + + + + + + Any process that modulates the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells. + dph + 2010-03-16T11:47:05Z + biological_process + GO:0061074 + regulation of neural retina development + + + + + Any process that modulates the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + Any process that increases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells. + dph + 2010-03-16T11:59:48Z + biological_process + GO:0061075 + positive regulation of neural retina development + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that increases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + Any process that decreases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells. + dph + 2010-03-16T12:46:11Z + biological_process + GO:0061076 + negative regulation of neural retina development + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that decreases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the left horn of the sinus venosus from its initial formation to the mature structure. + dph + 2010-04-08T02:40:27Z + biological_process + GO:0061079 + left horn of sinus venosus development + + + + + The progression of the left horn of the sinus venosus from its initial formation to the mature structure. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the right horn of the sinus venosus from its formation to the mature structure. + dph + 2010-04-08T02:45:10Z + biological_process + GO:0061080 + right horn of sinus venosus development + + + + + The progression of the right horn of the sinus venosus from its formation to the mature structure. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the rate, frequency, or extent of protein tyrosine kinase activity. + dph + 2010-04-26T02:34:53Z + biological_process + GO:0061097 + regulation of protein tyrosine kinase activity + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the rate, frequency, or extent of protein tyrosine kinase activity. + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + Any process that increases the rate, frequency, or extent of protein tyrosine kinase activity. + dph + 2010-04-26T02:34:53Z + biological_process + GO:0061098 + positive regulation of protein tyrosine kinase activity + + + + + Any process that increases the rate, frequency, or extent of protein tyrosine kinase activity. + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + Any process that decreases the rate, frequency, or extent of protein tyrosine kinase activity. + dph + 2010-04-26T02:34:53Z + biological_process + GO:0061099 + negative regulation of protein tyrosine kinase activity + + + + + Any process that decreases the rate, frequency, or extent of protein tyrosine kinase activity. + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a neuroendocrine cell. A neuroendocrine cell is a cell that receives input form a neuron which controls the secretion of an endocrine substance. + dph + 2010-04-28T09:42:20Z + biological_process + GO:0061101 + neuroendocrine cell differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a neuroendocrine cell. A neuroendocrine cell is a cell that receives input form a neuron which controls the secretion of an endocrine substance. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an adrenal chromaffin cell. An adrenal chromaffin cell is a neuroendocrine cell that stores epinephrine secretory vesicles. + dph + 2010-04-29T08:27:53Z + biological_process + GO:0061104 + adrenal chromaffin cell differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an adrenal chromaffin cell. An adrenal chromaffin cell is a neuroendocrine cell that stores epinephrine secretory vesicles. + GOC:dph + + + + + + + + + + + + + + + + + + + + + The progression of the seminal vesicle over time, from its formation to the mature structure. The seminal vesicle is a gland that contributes to the production of semen. + dph + 2010-04-30T10:17:30Z + biological_process + GO:0061107 + seminal vesicle development + + + + + The progression of the seminal vesicle over time, from its formation to the mature structure. The seminal vesicle is a gland that contributes to the production of semen. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the seminal vesicle epithelium over time, from its formation to the mature structure. + dph + 2010-04-30T10:19:54Z + biological_process + GO:0061108 + seminal vesicle epithelium development + + + + + The progression of the seminal vesicle epithelium over time, from its formation to the mature structure. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + Morphogenesis of the pancreas. Morphogenesis is the process in which anatomical structures are generated and organized. + dph + 2010-05-05T11:55:30Z + biological_process + GO:0061113 + pancreas morphogenesis + + + + + Morphogenesis of the pancreas. Morphogenesis is the process in which anatomical structures are generated and organized. + GOC:dph + + + + + + + + + + + + + + + + + + + The process in which the branches of the pancreas are generated and organized. + dph + 2010-05-05T12:03:04Z + biological_process + GO:0061114 + branching involved in pancreas morphogenesis + + + + + The process in which the branches of the pancreas are generated and organized. + GOC:dph + + + + + + + + + + + + + + + + + + + + Any process that decreases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart. + dph + 2010-05-17T07:31:28Z + biological_process + GO:0061117 + negative regulation of heart growth + + + + + Any process that decreases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart. + GOC:dph + GOC:hjd + + + + + + + + + + + + + + + + + + + + + The morphogenetic process in which the foregut region specified to become the pancreas forms a bud. + dph + 2010-05-17T09:33:40Z + biological_process + GO:0061130 + pancreatic bud formation + + + + + The morphogenetic process in which the foregut region specified to become the pancreas forms a bud. + GOC:dph + + + + + + + + + + The process in which the anatomical structures of a branched epithelium are generated and organized. + dph + 2010-05-25T09:05:34Z + biological_process + GO:0061138 + morphogenesis of a branching epithelium + + + + + The process in which the anatomical structures of a branched epithelium are generated and organized. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of a primary alveolar septum over time, from its formation to the mature structure. A primary alveolar septum is a specialized epithelium that surrounds the saccule as it forms. + dph + 2010-05-25T10:21:27Z + biological_process + GO:0061143 + alveolar primary septum development + + + + + The progression of a primary alveolar septum over time, from its formation to the mature structure. A primary alveolar septum is a specialized epithelium that surrounds the saccule as it forms. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of a secondary alveolar septum over time, from its formation to the mature structure. A secondary alveolar septum is a specialized epithelium that subdivides the initial saccule. + dph + 2010-05-25T10:43:55Z + biological_process + GO:0061144 + alveolar secondary septum development + + + + + The progression of a secondary alveolar septum over time, from its formation to the mature structure. A secondary alveolar septum is a specialized epithelium that subdivides the initial saccule. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a Peyer's patch is generated and organized. Peyer's patches are typically found as nodules associated with gut epithelium with distinct internal structures including B- and T-zones for the activation of lymphocytes. + dph + 2010-05-26T06:46:23Z + biological_process + GO:0061146 + Peyer's patch morphogenesis + + + + + The process in which a Peyer's patch is generated and organized. Peyer's patches are typically found as nodules associated with gut epithelium with distinct internal structures including B- and T-zones for the activation of lymphocytes. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the endocardial endothelium over time, from its initial formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. + dph + 2010-06-03T09:15:31Z + biological_process + GO:0061147 + endocardial endothelium development + + + + + The progression of the endocardial endothelium over time, from its initial formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. + GOC:dph + + + + + + + + + + + + + + + + + + + A process which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix of the endocardium. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. + dph + 2010-06-03T09:18:02Z + extracellular matrix organisation involved in endocardium development + biological_process + GO:0061148 + extracellular matrix organization involved in endocardium development + + + + + A process which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix of the endocardium. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers. + GOC:dph + + + + + extracellular matrix organisation involved in endocardium development + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the trachea submucosa over time from its formation to the mature structure. The trachea submucosa is made up of the glands and elastic tissue that lie under the mucosa in the trachea. + dph + 2010-06-07T09:58:40Z + biological_process + GO:0061152 + trachea submucosa development + + + + + The progression of the trachea submucosa over time from its formation to the mature structure. The trachea submucosa is made up of the glands and elastic tissue that lie under the mucosa in the trachea. + GOC:dph + GOC:yaf + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of a trachea gland over time, from its formation to the mature structure. Trachea glands are found under the mucus of the trachea and secrete mucus, and agents that help protect the lung from injury and infection. + dph + 2010-06-07T10:10:51Z + biological_process + GO:0061153 + trachea gland development + + + + + The progression of a trachea gland over time, from its formation to the mature structure. Trachea glands are found under the mucus of the trachea and secrete mucus, and agents that help protect the lung from injury and infection. + GOC:dph + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of a tube are generated and organized from an endothelium. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells. + dph + 2010-06-15T09:05:00Z + biological_process + GO:0061154 + endothelial tube morphogenesis + + + + + The process in which the anatomical structures of a tube are generated and organized from an endothelium. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells. + GOC:dph + GOC:yaf + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of a tube are generated and organized from the pulmonary artery endothelium. An pulmonary artery endothelium is an epithelium that lines the pulmonary artery. + dph + 2010-06-15T09:09:04Z + biological_process + GO:0061155 + pulmonary artery endothelial tube morphogenesis + + + + + The process in which the anatomical structures of a tube are generated and organized from the pulmonary artery endothelium. An pulmonary artery endothelium is an epithelium that lines the pulmonary artery. + GOC:dph + GOC:yaf + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the pulmonary artery are generated and organized. The pulmonary artery is the artery that carries blood from the heart to the lungs. + dph + 2010-06-15T09:13:47Z + biological_process + GO:0061156 + pulmonary artery morphogenesis + + + + + The process in which the anatomical structures of the pulmonary artery are generated and organized. The pulmonary artery is the artery that carries blood from the heart to the lungs. + GOC:dph + GOC:yaf + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud. + dph + 2010-06-25T01:03:29Z + biological_process + GO:0061168 + regulation of hair follicle placode formation + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud. + GOC:dph + + + + + + + + + + + + + + + + + + + Any process that increases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud. + dph + 2010-06-25T01:08:50Z + biological_process + GO:0061169 + positive regulation of hair placode formation + + + + + Any process that increases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + Any process that decreases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud. + dph + 2010-06-25T01:10:48Z + biological_process + GO:0061170 + negative regulation of hair follicle placode formation + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that decreases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose. + dph + 2010-07-13T09:38:42Z + regulation of insulin secretion in response to glucose + biological_process + GO:0061178 + regulation of insulin secretion involved in cellular response to glucose stimulus + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose. + GOC:BHF + GOC:dph + + + + + regulation of insulin secretion in response to glucose + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + Any process that decreases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose. + dph + 2010-07-13T09:41:46Z + negative regulation of insulin secretion involved in cellular response to glucose + biological_process + negative regulation of insulin secretion in response to glucose + GO:0061179 + negative regulation of insulin secretion involved in cellular response to glucose stimulus + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that decreases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose. + GOC:BHF + GOC:dph + + + + + negative regulation of insulin secretion involved in cellular response to glucose + GOC:bf + + + + + negative regulation of insulin secretion in response to glucose + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the mammary gland epithelium over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. + dph + 2010-07-14T08:18:24Z + breast epithelium development + biological_process + GO:0061180 + mammary gland epithelium development + + + + + The process whose specific outcome is the progression of the mammary gland epithelium over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. + GOC:dph + GOC:yaf + + + + + breast epithelium development + GOC:dph + + + + + + + + + + + + + + + + + + + + + Any process that modulates the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate. + dph + 2010-07-14T08:28:52Z + biological_process + GO:0061181 + regulation of chondrocyte development + + + + + Any process that modulates the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate. + GOC:BHF + GOC:dph + + + + + + + + + + + + + + + + + + + + + + Any process that decreases the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate. + dph + 2010-07-14T08:33:05Z + biological_process + GO:0061182 + negative regulation of chondrocyte development + + + + + Any process that decreases the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate. + GOC:BHF + GOC:dph + + + + + + + + + + + + + + + + + + + Any process that modulates the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin. + dph + 2010-07-14T08:40:26Z + biological_process + GO:0061183 + regulation of dermatome development + + + + + Any process that modulates the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin. + GOC:BHF + GOC:dph + + + + + + + + + + + + + + + + + + + + Any process that increases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin. + dph + 2010-07-14T08:42:03Z + biological_process + GO:0061184 + positive regulation of dermatome development + + + + + Any process that increases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin. + GOC:BHF + GOC:dph + + + + + + + + + + + + + + + + + + + + Any process that decreases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin. + dph + 2010-07-14T08:43:08Z + biological_process + GO:0061185 + negative regulation of dermatome development + + + + + Any process that decreases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin. + GOC:BHF + GOC:dph + + + + + + + + + + + + + + + + + + + Any process that increases the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra. + dph + 2010-07-14T09:17:23Z + biological_process + GO:0061189 + positive regulation of sclerotome development + + + + + Any process that increases the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra. + GOC:BHF + GOC:dph + + + + + + + + + + + + + + + + + + + Any process that modulates the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra. + dph + 2010-07-14T09:19:47Z + biological_process + GO:0061190 + regulation of sclerotome development + + + + + Any process that modulates the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the taste bud over time, from its formation to the mature state. The taste bud is a specialized area of the tongue that contains taste receptors. + dph + 2010-07-27T10:55:08Z + biological_process + GO:0061193 + taste bud development + + + + + The progression of the taste bud over time, from its formation to the mature state. The taste bud is a specialized area of the tongue that contains taste receptors. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the taste bud are generated and organized. The taste bud is a specialized area of the tongue that contains taste receptors. + dph + 2010-07-27T11:01:31Z + biological_process + GO:0061194 + taste bud morphogenesis + + + + + The process in which the anatomical structures of the taste bud are generated and organized. The taste bud is a specialized area of the tongue that contains taste receptors. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + The developmental process pertaining to the initial formation of the taste bud from unspecified parts. The taste bud is a specialized area of the tongue that contains taste receptors. + dph + 2010-07-27T12:22:26Z + biological_process + GO:0061195 + taste bud formation + + + + + The developmental process pertaining to the initial formation of the taste bud from unspecified parts. The taste bud is a specialized area of the tongue that contains taste receptors. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the fungiform papilla over time, from its formation to the mature structure. The fungiform papilla is a mushroom-shaped papilla of the tongue. + dph + 2010-07-27T12:23:48Z + biological_process + GO:0061196 + fungiform papilla development + + + + + The progression of the fungiform papilla over time, from its formation to the mature structure. The fungiform papilla is a mushroom-shaped papilla of the tongue. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the fungiform papilla are generated and organized. The fungiform papilla is a mushroom-shaped papilla of the tongue. + dph + 2010-07-27T12:26:40Z + biological_process + GO:0061197 + fungiform papilla morphogenesis + + + + + The process in which the anatomical structures of the fungiform papilla are generated and organized. The fungiform papilla is a mushroom-shaped papilla of the tongue. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + The developmental process pertaining to the initial formation of a spongiform papilla from unspecified parts. The fungiform papilla is a mushroom-shaped papilla of the tongue. + dph + 2010-07-27T12:29:03Z + biological_process + GO:0061198 + fungiform papilla formation + + + + + The developmental process pertaining to the initial formation of a spongiform papilla from unspecified parts. The fungiform papilla is a mushroom-shaped papilla of the tongue. + GOC:dph + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the paramesonephric duct over time, from its formation to the mature structure. Mullerian ducts (or paramesonephric ducts) are paired ducts of the embryo that run down the lateral sides of the urogenital ridge and terminate at the mullerian eminence in the primitive urogenital sinus. In the female, they will develop to form the fallopian tubes, uterus, cervix, and the upper portion of the vagina; in the male, they are lost. These ducts are made of tissue of mesodermal origin. + dph + 2010-07-30T10:54:47Z + Mullerian duct development + biological_process + GO:0061205 + paramesonephric duct development + + + + + The process whose specific outcome is the progression of the paramesonephric duct over time, from its formation to the mature structure. Mullerian ducts (or paramesonephric ducts) are paired ducts of the embryo that run down the lateral sides of the urogenital ridge and terminate at the mullerian eminence in the primitive urogenital sinus. In the female, they will develop to form the fallopian tubes, uterus, cervix, and the upper portion of the vagina; in the male, they are lost. These ducts are made of tissue of mesodermal origin. + GOC:dph + GOC:yaf + + + + + Mullerian duct development + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the mesonephros are generated and organized. + dph + 2010-08-17T03:11:10Z + Wolffian body morphogenesis + biological_process + GO:0061206 + mesonephros morphogenesis + + + + + The process in which the anatomical structures of the mesonephros are generated and organized. + GOC:mtg_kidney_jan10 + + + + + Wolffian body morphogenesis + GOC:dph + + + + + + + + + + + + + + + + + + + The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephros as it progresses from its formation to the mature state. + dph + 2010-08-17T03:21:23Z + biological_process + GO:0061208 + cell differentiation involved in mesonephros development + + + + + The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephros as it progresses from its formation to the mature state. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + The multiplication or reproduction of cells, resulting in the expansion of the population in the mesonephros. + dph + 2010-08-17T03:22:46Z + biological_process + GO:0061209 + cell proliferation involved in mesonephros development + + + + + The multiplication or reproduction of cells, resulting in the expansion of the population in the mesonephros. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mesonephros over time, from its formation to the mature organ. + dph + 2010-08-17T03:24:08Z + cell-cell signalling involved in mesonephros development + biological_process + GO:0061210 + cell-cell signaling involved in mesonephros development + + + + + Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mesonephros over time, from its formation to the mature organ. + GOC:mtg_kidney_jan10 + + + + + cell-cell signalling involved in mesonephros development + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a collecting duct in the mesonephros over time, from its formation to the mature structure. The collecting duct regulates water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder. + dph + 2010-08-17T03:25:51Z + biological_process + GO:0061211 + mesonephric collecting duct development + + + + + The process whose specific outcome is the progression of a collecting duct in the mesonephros over time, from its formation to the mature structure. The collecting duct regulates water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the juxtaglomerular apparatus in the mesonephros over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate. + dph + 2010-08-17T03:27:36Z + biological_process + GO:0061212 + mesonephric juxtaglomerular apparatus development + + + + + The process whose specific outcome is the progression of the juxtaglomerular apparatus in the mesonephros over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + Any process that increases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. + dph + 2010-08-17T03:39:35Z + biological_process + GO:0061213 + positive regulation of mesonephros development + + + + + Any process that increases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of smooth muscle in the mesonephros over time, from its formation to the mature structure. + dph + 2010-08-17T03:29:54Z + biological_process + GO:0061214 + mesonephric smooth muscle tissue development + + + + + The process whose specific outcome is the progression of smooth muscle in the mesonephros over time, from its formation to the mature structure. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a nephron in the mesonephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney. + dph + 2010-08-17T03:31:08Z + biological_process + GO:0061215 + mesonephric nephron development + + + + + The process whose specific outcome is the progression of a nephron in the mesonephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + Any process that modulates the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine. + dph + 2010-08-17T03:35:31Z + biological_process + GO:0061217 + regulation of mesonephros development + + + + + Any process that modulates the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + Any process that decreases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. + dph + 2010-08-17T03:43:06Z + biological_process + GO:0061218 + negative regulation of mesonephros development + + + + + Any process that decreases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The biological process whose specific outcome is the progression of a mesonephric mesenchyme from an initial condition to its mature state. This process begins with the formation of mesonephric mesenchyme and ends with the mature structure. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros. + dph + 2010-08-17T03:45:44Z + biological_process + GO:0061219 + mesonephric mesenchyme development + + + + + The biological process whose specific outcome is the progression of a mesonephric mesenchyme from an initial condition to its mature state. This process begins with the formation of mesonephric mesenchyme and ends with the mature structure. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the mesonephric macula densa over time, from its formation to the mature structure. The mesonephric macula densa is an area of specialized cells in the distal tubule of the mesonephros that makes contact with the vascular pole of the glomerulus. + dph + 2010-08-19T01:11:41Z + biological_process + GO:0061220 + mesonephric macula densa development + + + + + The process whose specific outcome is the progression of the mesonephric macula densa over time, from its formation to the mature structure. The mesonephric macula densa is an area of specialized cells in the distal tubule of the mesonephros that makes contact with the vascular pole of the glomerulus. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of a mesonephric mesenchymal tissue are generated and organized. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros. + dph + 2010-08-19T01:17:38Z + biological_process + GO:0061221 + mesonephric mesenchyme morphogenesis + + + + + The process in which the anatomical structures of a mesonephric mesenchymal tissue are generated and organized. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the mesonephric glomerulus over time from its initial formation until its mature state. The mesonephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or mesonephros. + dph + 2010-08-19T01:26:00Z + biological_process + GO:0061224 + mesonephric glomerulus development + + + + + The progression of the mesonephric glomerulus over time from its initial formation until its mature state. The mesonephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or mesonephros. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + Any developmental process that results in the creation of defined areas or spaces within the mesonephros to which cells respond and eventually are instructed to differentiate. + dph + 2010-08-19T02:22:22Z + mesonephros pattern specification + biological_process + mesonephros pattern formation + GO:0061227 + pattern specification involved in mesonephros development + + + + + Any developmental process that results in the creation of defined areas or spaces within the mesonephros to which cells respond and eventually are instructed to differentiate. + GOC:mtg_kidney_jan10 + + + + + mesonephros pattern specification + GOC:mtg_kidney_jan10 + + + + + mesonephros pattern formation + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the mesonephric nephron are generated and organized. A mesonephric nephron is the functional unit of the mesonephros. + dph + 2010-08-19T02:26:24Z + biological_process + GO:0061228 + mesonephric nephron morphogenesis + + + + + The process in which the anatomical structures of the mesonephric nephron are generated and organized. A mesonephric nephron is the functional unit of the mesonephros. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The biological process whose specific outcome is the progression of a mesonephric glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the mesonephric glomerulus vasculature and ends with the mature structure. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus. + dph + 2010-08-19T02:47:06Z + biological_process + GO:0061231 + mesonephric glomerulus vasculature development + + + + + The biological process whose specific outcome is the progression of a mesonephric glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the mesonephric glomerulus vasculature and ends with the mature structure. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the mesonephric glomerular epithelium over time, from its formation to the mature structure. The mesonephric glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus in the mesonephros. The mesonephric glomerular epithelium consists of both parietal and visceral epithelium. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros. + dph + 2010-08-19T02:49:46Z + biological_process + GO:0061232 + mesonephric glomerular epithelium development + + + + + The process whose specific outcome is the progression of the mesonephric glomerular epithelium over time, from its formation to the mature structure. The mesonephric glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus in the mesonephros. The mesonephric glomerular epithelium consists of both parietal and visceral epithelium. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the mesonephros. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the mesonephric glomerulus are generated and organized. The mesonephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate mesonephros. + dph + 2010-08-19T02:53:35Z + biological_process + GO:0061234 + mesonephric glomerulus morphogenesis + + + + + The process in which the anatomical structures of the mesonephric glomerulus are generated and organized. The mesonephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate mesonephros. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the mesonephric comma-shaped body is generated and organized. The mesonephric comma-shaped body is the precursor structure to the mesonephric S-shaped body that contributes to the morphogenesis of a nephron in the mesonephros. + dph + 2010-08-19T03:00:21Z + biological_process + GO:0061236 + mesonephric comma-shaped body morphogenesis + + + + + The process in which the mesonephric comma-shaped body is generated and organized. The mesonephric comma-shaped body is the precursor structure to the mesonephric S-shaped body that contributes to the morphogenesis of a nephron in the mesonephros. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of a mesonephric nephron tubule are generated and organized. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros. + dph + 2010-08-19T03:09:26Z + biological_process + GO:0061240 + mesonephric nephron tubule morphogenesis + + + + + The process in which the anatomical structures of a mesonephric nephron tubule are generated and organized. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the mesonephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The mesonephric nephron epithelium is a tissue that covers the surface of a nephron in the mesonephros. + dph + 2010-08-19T03:11:59Z + biological_process + GO:0061241 + mesonephric nephron epithelium development + + + + + The process whose specific outcome is the progression of the mesonephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The mesonephric nephron epithelium is a tissue that covers the surface of a nephron in the mesonephros. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + The progression of a mesonephric nephron tubule over time, from its initial formation to the mature structure. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros. + dph + 2010-08-19T03:17:00Z + biological_process + GO:0061242 + mesonephric nephron tubule development + + + + + The progression of a mesonephric nephron tubule over time, from its initial formation to the mature structure. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the mesonephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the mesonephric nephron epithelium, and is formed by the condensation of mesenchymal cells. + dph + 2010-08-19T03:20:21Z + biological_process + GO:0061243 + mesonephric renal vesicle morphogenesis + + + + + The process in which the anatomical structures of the mesonephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the mesonephric nephron epithelium, and is formed by the condensation of mesenchymal cells. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the mesonephric S-shaped body is generated and organized. The mesonephric S-shaped body is the successor of the mesonephric comma-shaped body that contributes to the morphogenesis of a nephron in the mesonephros. + dph + 2010-08-19T03:23:55Z + biological_process + GO:0061244 + mesonephric S-shaped body morphogenesis + + + + + The process in which the mesonephric S-shaped body is generated and organized. The mesonephric S-shaped body is the successor of the mesonephric comma-shaped body that contributes to the morphogenesis of a nephron in the mesonephros. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the mesonephric glomerular mesangium over time, from its formation to the mature structure. The mesonephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the mesonephros, which helps to support the capillary loops in a renal glomerulus. + dph + 2010-08-30T12:59:25Z + biological_process + GO:0061247 + mesonephric glomerular mesangium development + + + + + The process whose specific outcome is the progression of the mesonephric glomerular mesangium over time, from its formation to the mature structure. The mesonephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the mesonephros, which helps to support the capillary loops in a renal glomerulus. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the mesonephric glomerulus vasculature are generated and organized. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus. + dph + 2010-08-30T01:11:34Z + biological_process + GO:0061248 + mesonephric glomerulus vasculature morphogenesis + + + + + The process in which the anatomical structures of the mesonephric glomerulus vasculature are generated and organized. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to a mesonephric glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts. + dph + 2010-08-30T01:17:08Z + biological_process + GO:0061249 + mesonephric glomerular capillary formation + + + + + The process that gives rise to a mesonephric glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephros. + dph + 2010-08-30T02:35:15Z + biological_process + mesonephric mesenchyme to epithelial transition + GO:0061261 + mesenchymal to epithelial transition involved in mesonephros morphogenesis + + + + + A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephros. + GOC:mtg_kidney_jan10 + + + + + mesonephric mesenchyme to epithelial transition + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The developmental process pertaining to the initial formation of the mesonephros. + dph + 2010-08-30T02:41:20Z + mesonephros formation + biological_process + GO:0061262 + mesonephric renal vesicle formation + + + + + The developmental process pertaining to the initial formation of the mesonephros. + GOC:mtg_kidney_jan10 + + + + + mesonephros formation + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephric renal vesicle. + dph + 2010-08-30T03:26:30Z + biological_process + GO:0061271 + mesenchymal to epithelial transition involved in mesonephric renal vesicle formation + + + + + A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephric renal vesicle. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the mesonephric connecting tubule over time, from its formation to the mature structure. The mesonephric connecting tubule is a tubular segment of the mesonephric nephron; it connects the distal tubule to the collecting duct in the mesonephros. + dph + 2010-09-02T12:00:56Z + mesonephric collecting tubule development + biological_process + mesonephric connecting duct development + GO:0061272 + mesonephric connecting tubule development + + + + + The process whose specific outcome is the progression of the mesonephric connecting tubule over time, from its formation to the mature structure. The mesonephric connecting tubule is a tubular segment of the mesonephric nephron; it connects the distal tubule to the collecting duct in the mesonephros. + GOC:mtg_kidney_jan10 + + + + + mesonephric collecting tubule development + GOC:dph + + + + + mesonephric connecting duct development + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of a mesonephric distal tubule are generated and organized. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the macula densa and extends to the mesonephric connecting tubule. + dph + 2010-09-02T12:12:00Z + biological_process + GO:0061273 + mesonephric distal tubule morphogenesis + + + + + The process in which the anatomical structures of a mesonephric distal tubule are generated and organized. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the macula densa and extends to the mesonephric connecting tubule. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the mesonephric distal tubule over time, from its formation to the mature structure. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the terminal segment of the proximal tubule and ends at the mesonephric connecting tubule. + dph + 2010-09-02T12:16:25Z + biological_process + GO:0061274 + mesonephric distal tubule development + + + + + The process whose specific outcome is the progression of the mesonephric distal tubule over time, from its formation to the mature structure. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the terminal segment of the proximal tubule and ends at the mesonephric connecting tubule. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + The progression of the mesonephric proximal tubule over time, from its formation to the mature structure. The mesonephric proximal tubule extends from the capsule to the distal tubule. + dph + 2010-09-02T01:08:05Z + biological_process + GO:0061275 + mesonephric proximal tubule development + + + + + The progression of the mesonephric proximal tubule over time, from its formation to the mature structure. The mesonephric proximal tubule extends from the capsule to the distal tubule. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of a mesonephric proximal tubule are generated and organized. The mesonephric proximal tubule extends from the capsule to the distal tubule. + dph + 2010-09-02T01:11:02Z + biological_process + GO:0061276 + mesonephric proximal tubule morphogenesis + + + + + The process in which the anatomical structures of a mesonephric proximal tubule are generated and organized. The mesonephric proximal tubule extends from the capsule to the distal tubule. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The developmental process pertaining to the initial formation of a mesonephric nephron tubule from unspecified parts. A mesonephric nephron tubule is an epithelial tube that is part of a nephron in the mesonephros. + dph + 2010-09-02T01:16:21Z + biological_process + GO:0061277 + mesonephric nephron tubule formation + + + + + The developmental process pertaining to the initial formation of a mesonephric nephron tubule from unspecified parts. A mesonephric nephron tubule is an epithelial tube that is part of a nephron in the mesonephros. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric nephron tubule morphogenesis. + dph + 2010-09-02T01:18:53Z + biological_process + GO:0061278 + epithelial cell migration involved in mesonephric nephron tubule morphogenesis + + + + + The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric nephron tubule morphogenesis. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric distal tubule morphogenesis. + dph + 2010-09-02T01:20:56Z + biological_process + GO:0061279 + epithelial cell migration involved in mesonephric distal tubule morphogenesis + + + + + The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric distal tubule morphogenesis. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric proximal tubule morphogenesis. + dph + 2010-09-02T01:23:43Z + biological_process + GO:0061280 + epithelial cell migration involved in mesonephric proximal tubule morphogenesis + + + + + The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric proximal tubule morphogenesis. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the mesonephric capsule over time, from its formation to the mature structure. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. + dph + 2010-09-02T01:50:06Z + biological_process + GO:0061285 + mesonephric capsule development + + + + + The progression of the mesonephric capsule over time, from its formation to the mature structure. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the mesonephric capsule are generated and organized. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. + dph + 2010-09-02T01:53:31Z + biological_process + GO:0061286 + mesonephric capsule morphogenesis + + + + + The process in which the anatomical structures of the mesonephric capsule are generated and organized. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The developmental process pertaining to the initial formation of a mesonephric capsule from unspecified parts. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. + dph + 2010-09-02T01:55:03Z + biological_process + GO:0061287 + mesonephric capsule formation + + + + + The developmental process pertaining to the initial formation of a mesonephric capsule from unspecified parts. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the vasculature of the retina over time, from its formation to the mature structure. + dph + 2010-09-06T03:27:06Z + retinal vasculature development + biological_process + GO:0061298 + retina vasculature development in camera-type eye + + + + + The process whose specific outcome is the progression of the vasculature of the retina over time, from its formation to the mature structure. + GOC:BHF + GOC:dph + + + + + retinal vasculature development + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the vasculature of the retina is generated and organized. + dph + 2010-09-06T03:28:25Z + retinal vasculature morphogenesis + biological_process + GO:0061299 + retina vasculature morphogenesis in camera-type eye + + + + + The process in which the vasculature of the retina is generated and organized. + GOC:BHF + GOC:dph + + + + + retinal vasculature morphogenesis + GOC:dph + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the vasculature of the cerebellum over time, from its formation to the mature structure. + dph + 2010-09-06T03:36:40Z + biological_process + GO:0061300 + cerebellum vasculature development + + + + + The process whose specific outcome is the progression of the vasculature of the cerebellum over time, from its formation to the mature structure. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the vasculature of the cerebellum is generated and organized. + dph + 2010-09-06T03:38:05Z + biological_process + GO:0061301 + cerebellum vasculature morphogenesis + + + + + The process in which the vasculature of the cerebellum is generated and organized. + GOC:BHF + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the cornea over time, from its formation to the mature structure. The cornea is the transparent structure that covers the anterior of the eye. + dph + 2010-09-14T02:09:08Z + biological_process + GO:0061303 + cornea development in camera-type eye + + + + + The progression of the cornea over time, from its formation to the mature structure. The cornea is the transparent structure that covers the anterior of the eye. + GOC:dph + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a blood vessel of the retina over time, from its formation to the mature structure. + dph + 2010-09-16T09:02:59Z + biological_process + GO:0061304 + retinal blood vessel morphogenesis + + + + + The process whose specific outcome is the progression of a blood vessel of the retina over time, from its formation to the mature structure. + GOC:BHF + GOC:dph + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of a cardiac neural crest cell that will migrate to the heart and contribute to its development. Cardiac neural crest cells are specialized cells that migrate toward the heart from the third, fourth and sixth pharyngeal arches. + dph + 2010-09-23T08:50:56Z + biological_process + GO:0061307 + cardiac neural crest cell differentiation involved in heart development + + + + + The process in which a relatively unspecialized cell acquires specialized features of a cardiac neural crest cell that will migrate to the heart and contribute to its development. Cardiac neural crest cells are specialized cells that migrate toward the heart from the third, fourth and sixth pharyngeal arches. + GOC:dph + GOC:mtg_heart + PMID:19705442 + + + + + + + + + + + + + + + + + + + + + + + + + The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the development of the heart. + dph + 2010-09-23T09:01:49Z + biological_process + GO:0061308 + cardiac neural crest cell development involved in heart development + + + + + The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the development of the heart. + GOC:dph + GOC:mtg_heart + + + + + + + + + + + + + + + + + + + The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the shaping of the outflow tract. + dph + 2010-09-23T09:08:37Z + biological_process + GO:0061309 + cardiac neural crest cell development involved in outflow tract morphogenesis + + + + + The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the shaping of the outflow tract. + GOC:dph + GOC:mtg_heart + + + + + + + + + + + + + + + + + + + The series of molecular signals initiated by a ligand the binding to its receptor on the surface of a cell, which contributes to the progression of the heart over time. + dph + 2010-09-23T09:18:32Z + cell surface receptor linked signaling pathway involved in heart development + cell surface receptor linked signalling pathway involved in heart development + biological_process + GO:0061311 + cell surface receptor signaling pathway involved in heart development + + + + + The series of molecular signals initiated by a ligand the binding to its receptor on the surface of a cell, which contributes to the progression of the heart over time. + GOC:dph + GOC:mtg_heart + GOC:signaling + + + + + cell surface receptor linked signaling pathway involved in heart development + GOC:bf + + + + + cell surface receptor linked signalling pathway involved in heart development + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a renal filtration cell. Renal filtration cells are specialized cells of the renal system that filter fluids by charge, size or both. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. + dph + 2010-09-24T12:18:35Z + biological_process + GO:0061318 + renal filtration cell differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a renal filtration cell. Renal filtration cells are specialized cells of the renal system that filter fluids by charge, size or both. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state. + GOC:dph + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the heart. + dph + 2010-09-28T09:05:26Z + biological_process + GO:0061323 + cell proliferation involved in heart morphogenesis + + + + + The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the heart. + GOC:dph + GOC:mtg_heart + + + + + + + + + + + + + + + + + + + The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the outflow tract. + dph + 2010-09-28T09:29:30Z + biological_process + GO:0061325 + cell proliferation involved in outflow tract morphogenesis + + + + + The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the outflow tract. + GOC:dph + GOC:mtg_heart + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the renal tubule over time from its formation to the mature form. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis. + dph + 2010-09-28T12:50:43Z + biological_process + GO:0061326 + renal tubule development + + + + + The progression of the renal tubule over time from its formation to the mature form. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis. + GOC:dph + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population and contributing to the shaping of a Malpighian tubule. + dph + 2010-09-28T02:01:02Z + biological_process + GO:0061331 + epithelial cell proliferation involved in Malpighian tubule morphogenesis + + + + + The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population and contributing to the shaping of a Malpighian tubule. + GOC:dph + GOC:mtg_kidney_jan10 + PMID:19783135 + + + + + + + + + + + + + + + + + + + + + + + + + + The morphogenetic process in which a bud forms from the embryonic hindgut tube to form the Malpighian tubule. A bud is a protrusion that forms from the tube by localized changes in cell shape and position. + dph + 2010-09-28T01:39:32Z + Malpighian tubule formation + biological_process + GO:0061332 + Malpighian tubule bud morphogenesis + + + + + The morphogenetic process in which a bud forms from the embryonic hindgut tube to form the Malpighian tubule. A bud is a protrusion that forms from the tube by localized changes in cell shape and position. + GOC:dph + GOC:mtg_kidney_jan10 + PMID:19783135 + + + + + Malpighian tubule formation + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the renal tubule is generated by specification of cell fate, through the maintenance of cell polarity, regulated cell proliferation and morphogenetic cell rearrangements, shape changes and growth. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis. + dph + 2010-09-28T01:43:04Z + biological_process + GO:0061333 + renal tubule morphogenesis + + + + + The process in which the renal tubule is generated by specification of cell fate, through the maintenance of cell polarity, regulated cell proliferation and morphogenetic cell rearrangements, shape changes and growth. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis. + GOC:dph + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + The movement of an epithelial cell with respect to other epithelial cells that contributes to the shaping of the Malpighian tubule. + dph + 2010-09-28T02:04:05Z + cell migration involved in Malpighian tubule morphogenesis + biological_process + GO:0061334 + cell rearrangement involved in Malpighian tubule morphogenesis + + + + + The movement of an epithelial cell with respect to other epithelial cells that contributes to the shaping of the Malpighian tubule. + GOC:dph + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + The growth of an epithelial cell dependent on cycles of endoreplication, where growth contributes to the shaping of the Malpighian tubule. + dph + 2010-09-28T02:08:25Z + biological_process + GO:0061335 + cell growth involved in Malpighian tubule morphogenesis + + + + + The growth of an epithelial cell dependent on cycles of endoreplication, where growth contributes to the shaping of the Malpighian tubule. + GOC:dph + GOC:mtg_kidney_jan10 + PMID:19783135 + + + + + + + + + + + + + + + + + + + The shape change of an epithelial cell from a columnar to squamous cell morphology that contributes to the shaping of the Malpighian tubule. + dph + 2010-09-28T02:11:47Z + biological_process + GO:0061336 + cell morphogenesis involved in Malpighian tubule morphogenesis + + + + + The shape change of an epithelial cell from a columnar to squamous cell morphology that contributes to the shaping of the Malpighian tubule. + GOC:dph + GOC:mtg_kidney_jan10 + PMID:19783135 + + + + + + + + + + + + + + + + + + + The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the shaping of the heart. + dph + 2010-09-29T11:34:06Z + biological_process + GO:0061343 + cell adhesion involved in heart morphogenesis + + + + + The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the shaping of the heart. + GOC:dph + GOC:mtg_heart + PMID:16860783 + + + + + + + + + + + + + + + + + + + Any process that modulates the extent of cell adhesion contributing to the shaping of the heart. + dph + 2010-09-29T11:35:27Z + biological_process + GO:0061344 + regulation of cell adhesion involved in heart morphogenesis + + + + + Any process that modulates the extent of cell adhesion contributing to the shaping of the heart. + GOC:dph + GOC:mtg_heart + PMID:16860783 + + + + + + + + + The multiplication or reproduction of neural precursor cells, resulting in the expansion of a cell population. A neural precursor cell is either a nervous system stem cell or a nervous system progenitor cell. + dph + 2010-10-01T11:06:04Z + biological_process + GO:0061351 + neural precursor cell proliferation + + + + + The multiplication or reproduction of neural precursor cells, resulting in the expansion of a cell population. A neural precursor cell is either a nervous system stem cell or a nervous system progenitor cell. + GOC:dph + GOC:yaf + + + + + + + + + + + + + + + + + + + + + + + + + + + The developmental process pertaining to the progression of the optic chiasm from its initial formation to the mature structure. The process begins when the pathfinding of the axons of the developing optic nerve cause some axons to cross at the midline of the brain and ends when the axons are mature. + dph + 2010-10-13T08:00:29Z + optic chiasm development + biological_process + GO:0061360 + optic chiasma development + + + + + The developmental process pertaining to the progression of the optic chiasm from its initial formation to the mature structure. The process begins when the pathfinding of the axons of the developing optic nerve cause some axons to cross at the midline of the brain and ends when the axons are mature. + GOC:dph + + + + + optic chiasm development + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the mammillary axonal complex over time, from its formation to the mature structure. The mammillary axonal complex is formed by the axons from the lateral, medial mammillary and the dorsal premammillary nuclei which share a branching pattern. Every neuron gives off one axonal stem that bifurcates into 2 branches. One of the branches is directed dorsally to the thalamus and another caudally to the midbrain. + dph + 2010-11-09T08:49:59Z + biological_process + GO:0061373 + mammillary axonal complex development + + + + + The progression of the mammillary axonal complex over time, from its formation to the mature structure. The mammillary axonal complex is formed by the axons from the lateral, medial mammillary and the dorsal premammillary nuclei which share a branching pattern. Every neuron gives off one axonal stem that bifurcates into 2 branches. One of the branches is directed dorsally to the thalamus and another caudally to the midbrain. + GOC:dph + GOC:yaf + PMID:10662642 + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the mammillothalamic axonal tract, from its formation to the mature structure. The mammillothalamic tract is the collection of axons that connects the two major subdivisions of the diencephalon (hypothalamus and thalamus) and closes the diencephalic circuit. + dph + 2010-11-09T08:54:43Z + biological_process + GO:0061374 + mammillothalamic axonal tract development + + + + + The progression of the mammillothalamic axonal tract, from its formation to the mature structure. The mammillothalamic tract is the collection of axons that connects the two major subdivisions of the diencephalon (hypothalamus and thalamus) and closes the diencephalic circuit. + GOC:dph + GOC:yaf + PMID:10662642 + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the mammillotectal tract over time, from its formation to the mature structure. The mammillotectal tract is the collection of axons that connects the ventral diencephalon to the superior colliculus. + dph + 2010-11-09T09:01:14Z + biological_process + GO:0061375 + mammillotectal axonal tract development + + + + + The progression of the mammillotectal tract over time, from its formation to the mature structure. The mammillotectal tract is the collection of axons that connects the ventral diencephalon to the superior colliculus. + GOC:dph + GOC:yaf + PMID:10662642 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the mammillotegmental tract progresses over time, from its formation to the mature structure. The mammillotegmental tract is the collection of axons that connects the ventral diencephalon to the tegmentum and pons. + dph + 2010-11-09T09:09:29Z + biological_process + GO:0061376 + mammillotegmental axonal tract development + + + + + The process in which the mammillotegmental tract progresses over time, from its formation to the mature structure. The mammillotegmental tract is the collection of axons that connects the ventral diencephalon to the tegmentum and pons. + GOC:dph + GOC:yaf + PMID:10662642 + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the mammary gland lobule over time, from its formation to the mature structure. A mammary gland lobule is a small rounded projection of the mammary gland. + dph + 2010-11-09T09:36:29Z + biological_process + GO:0061377 + mammary gland lobule development + + + + + The progression of the mammary gland lobule over time, from its formation to the mature structure. A mammary gland lobule is a small rounded projection of the mammary gland. + GOC:dph + GOC:yaf + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the corpora quadrigemina over time, from its formation to the mature structure. The corpora quadrigemina is a part of the midbrain that is made up of the superior and inferior colliculi. + dph + 2010-11-09T09:45:36Z + biological_process + GO:0061378 + corpora quadrigemina development + + + + + The progression of the corpora quadrigemina over time, from its formation to the mature structure. The corpora quadrigemina is a part of the midbrain that is made up of the superior and inferior colliculi. + GOC:dph + GOC:yaf + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the inferior colliculus over time, from its formation to the mature structure. The inferior colliculus (IC) (Latin, lower hill) is the principal midbrain nucleus of the auditory pathway and receives input from several more peripheral brainstem nuclei in the auditory pathway, as well as inputs from the auditory cortex. The inferior colliculus has three subdivisions: the central nucleus (CIC), a dorsal cortex (DCIC) by which it is surrounded, and an external cortex (ICX) which is located laterally. + dph + 2010-11-09T09:49:24Z + biological_process + GO:0061379 + inferior colliculus development + + + + + The process whose specific outcome is the progression of the inferior colliculus over time, from its formation to the mature structure. The inferior colliculus (IC) (Latin, lower hill) is the principal midbrain nucleus of the auditory pathway and receives input from several more peripheral brainstem nuclei in the auditory pathway, as well as inputs from the auditory cortex. The inferior colliculus has three subdivisions: the central nucleus (CIC), a dorsal cortex (DCIC) by which it is surrounded, and an external cortex (ICX) which is located laterally. + GOC:dph + GOC:yaf + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the superior colliculus over time, from its formation to the mature structure. The superior colliculus is also known as the optic tectum or simply tectum and is a paired structure that forms a major component of the vertebrate midbrain. + dph + 2010-11-09T09:51:00Z + biological_process + GO:0061380 + superior colliculus development + + + + + The process whose specific outcome is the progression of the superior colliculus over time, from its formation to the mature structure. The superior colliculus is also known as the optic tectum or simply tectum and is a paired structure that forms a major component of the vertebrate midbrain. + GOC:dph + GOC:yaf + + + + + + + + + + + + + + + + + + + + + The process of shaping a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue. + dph + 2010-12-02T08:51:45Z + biological_process + GO:0061383 + trabecula morphogenesis + + + + + The process of shaping a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue. + GOC:dph + + + + + + + + + + + + + + + + + + + + The process of shaping a trabecula in the heart. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue. + dph + 2010-12-02T08:54:20Z + biological_process + GO:0061384 + heart trabecula morphogenesis + + + + + The process of shaping a trabecula in the heart. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue. + GOC:dph + + + + + + + + + + + + + + + + + + + The multiplication or reproduction of fibroblasts, resulting in the expansion of a fibroblast population that contributes to the shaping of the heart. + dph + 2011-02-10T01:41:59Z + biological_process + GO:0061385 + fibroblast proliferation involved in heart morphogenesis + + + + + The multiplication or reproduction of fibroblasts, resulting in the expansion of a fibroblast population that contributes to the shaping of the heart. + GOC:dph + + + + + + + + + The process of shaping a trabecula in bone. A trabecula is a tissue element in the form of a small beam, strut or rod. + dph + 2012-02-07T10:15:36Z + biological_process + GO:0061430 + bone trabecula morphogenesis + + + + + The process of shaping a trabecula in bone. A trabecula is a tissue element in the form of a small beam, strut or rod. + GOC:BHF + GOC:dph + GOC:vk + + + + + + + + + + + + + + + The process whose specific outcome is the progression of vasculature of the renal system over time, from its formation to the mature structure. + dph + 2012-03-08T12:16:24Z + biological_process + GO:0061437 + renal system vasculature development + + + + + The process whose specific outcome is the progression of vasculature of the renal system over time, from its formation to the mature structure. + GOC:dph + GOC:mtg_kidney_jan10 + PMID:11891195 + + + + + + + + + + + + + + + + The process in which the renal system vasculature is generated and organized. Morphogenesis pertains to the creation of form. + dph + 2012-03-08T12:21:56Z + biological_process + GO:0061438 + renal system vasculature morphogenesis + + + + + The process in which the renal system vasculature is generated and organized. Morphogenesis pertains to the creation of form. + GOC:dph + GOC:mtg_kidney_jan10 + PMID:11891195 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the kidney vasculature is generated and organized. Morphogenesis pertains to the creation of form. + dph + 2012-03-08T12:30:11Z + biological_process + GO:0061439 + kidney vasculature morphogenesis + + + + + The process in which the kidney vasculature is generated and organized. Morphogenesis pertains to the creation of form. + GOC:dph + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the vasculature of the kidney over time, from its formation to the mature structure. + dph + 2012-03-08T12:39:09Z + biological_process + GO:0061440 + kidney vasculature development + + + + + The process whose specific outcome is the progression of the vasculature of the kidney over time, from its formation to the mature structure. + GOC:dph + GOC:mtg_kidney_jan10 + PMID:11891195 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of a renal artery is generated and organized. Renal arteries supply the kidneys with blood. + dph + 2012-03-08T12:42:09Z + biological_process + GO:0061441 + renal artery morphogenesis + + + + + The process in which the anatomical structure of a renal artery is generated and organized. Renal arteries supply the kidneys with blood. + GOC:mtg_kidney_jan10 + PMID:11891195 + + + + + + + + + + + + + + + + + + + + The progression of a connective tissue over time, from its formation to the mature structure. + dph + 2012-03-22T12:53:41Z + biological_process + GO:0061448 + connective tissue development + + + + + The progression of a connective tissue over time, from its formation to the mature structure. + GOC:BHF + + + + + + + + + + + + + + + + + + + + + + + + + + Trophoblast cell migration that is accomplished by extension and retraction of a pseudopodium. Trophoblast cells line the outside of the blastocyst. + dph + 2012-07-10T08:38:37Z + biological_process + GO:0061450 + trophoblast cell migration + + + + + Trophoblast cell migration that is accomplished by extension and retraction of a pseudopodium. Trophoblast cells line the outside of the blastocyst. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the retrotrapezoid nucleus (RTN) over time from it's initial formation to its mature state. The retrotrapezoid nucleus is a group of neurons in the rostral medulla, which are responsible regulating respiration. + dph + 2012-07-19T12:38:30Z + biological_process + GO:0061451 + retrotrapezoid nucleus development + + + + + The progression of the retrotrapezoid nucleus (RTN) over time from it's initial formation to its mature state. The retrotrapezoid nucleus is a group of neurons in the rostral medulla, which are responsible regulating respiration. + GOC:dph + + + + + + + + + + + + + + + + + + + + The component of the muscle cell projection membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. + dph + 2012-07-27T02:38:01Z + integral to muscle cell projection membrane + cellular_component + GO:0061455 + integral component of muscle cell projection membrane + + + + + The component of the muscle cell projection membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. + GOC:dos + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + The progression of the reproductive system over time from its formation to the mature structure. The reproductive system consists of the organs that function in reproduction. + dph + 2012-08-22T17:47:53Z + biological_process + GO:0061458 + reproductive system development + + + + + The progression of the reproductive system over time from its formation to the mature structure. The reproductive system consists of the organs that function in reproduction. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A process in which a protein is transported to, or maintained in, a location within a cilium. + + + + + + + dph + 2013-03-22T15:41:44Z + biological_process + GO:0061512 + protein localization to cilium + + + + + A process in which a protein is transported to, or maintained in, a location within a cilium. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a myeloid cell over time, from its formation to the mature structure. + dph + 2013-04-18T13:03:16Z + biological_process + GO:0061515 + myeloid cell development + + + + + The process whose specific outcome is the progression of a myeloid cell over time, from its formation to the mature structure. + GOC:dph + + + + + + + + + + + + + + + + + + + + The process of regulating the proliferation and elimination of macrophage cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. + dph + 2013-04-18T13:25:33Z + biological_process + GO:0061519 + macrophage homeostasis + + + + + The process of regulating the proliferation and elimination of macrophage cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. + GOC:dph + PMID:21727904 + + + + + + + + + + + + + + + + + + + + The process in which a precursor cell type acquires the specialized features of a Langerhans cell. + dph + 2013-04-18T13:29:07Z + biological_process + GO:0061520 + Langerhans cell differentiation + + + + + The process in which a precursor cell type acquires the specialized features of a Langerhans cell. + GOC:dph + PMID:22729249 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the formation of the central canal of the spinal cord from its formation to the mature structure. The central canal is a spinal cord structure that is part of the ventricular system and is filled with cerebral-spinal fluid and runs the length of the spinal cord. + dph + 2013-04-20T08:18:31Z + biological_process + GO:0061524 + central canal development + + + + + The process whose specific outcome is the formation of the central canal of the spinal cord from its formation to the mature structure. The central canal is a spinal cord structure that is part of the ventricular system and is filled with cerebral-spinal fluid and runs the length of the spinal cord. + GOC:cvs + GOC:dph + PMID:23409159 + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the hindgut over time, from its formation to the mature structure. The hindgut is part of the alimentary canal that lies posterior to the midgut. + dph + 2013-06-14T11:22:21Z + biological_process + GO:0061525 + hindgut development + + + + + The process whose specific outcome is the progression of the hindgut over time, from its formation to the mature structure. The hindgut is part of the alimentary canal that lies posterior to the midgut. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a ganglion over time, from its formation to the mature structure. + dph + 2013-07-10T08:36:12Z + gangliogenesis + biological_process + ganglia development + GO:0061548 + ganglion development + + + + + The process whose specific outcome is the progression of a ganglion over time, from its formation to the mature structure. + GOC:dph + + + + + gangliogenesis + GOC:BHF + GOC:rl + + + + + ganglia development + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a sympathetic ganglion over time, from its formation to the mature structure. + dph + 2013-07-10T08:38:01Z + biological_process + sympathetic ganglia development + GO:0061549 + sympathetic ganglion development + + + + + The process whose specific outcome is the progression of a sympathetic ganglion over time, from its formation to the mature structure. + GOC:BHF + GOC:rl + + + + + sympathetic ganglia development + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a cranial ganglion over time, from its formation to the mature structure. + dph + 2013-07-10T08:40:14Z + biological_process + cranial ganglia development + GO:0061550 + cranial ganglion development + + + + + The process whose specific outcome is the progression of a cranial ganglion over time, from its formation to the mature structure. + GOC:dph + + + + + cranial ganglia development + GOC:dph + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a trigeminal ganglion over time, from its formation to the mature structure. + dph + 2013-07-10T08:42:19Z + biological_process + trigeminal ganglia development + GO:0061551 + trigeminal ganglion development + + + + + The process whose specific outcome is the progression of a trigeminal ganglion over time, from its formation to the mature structure. + GOC:dph + + + + + trigeminal ganglia development + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of ganglion are generated and organized. + dph + 2013-07-10T08:44:57Z + biological_process + ganglia morphogenesis + GO:0061552 + ganglion morphogenesis + + + + + The process in which the anatomical structures of ganglion are generated and organized. + GOC:dph + + + + + ganglia morphogenesis + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for ganglion to attain its fully functional state. + dph + 2013-07-10T08:45:59Z + biological_process + ganglia maturation + GO:0061553 + ganglion maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for ganglion to attain its fully functional state. + GOC:dph + + + + + ganglia maturation + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to ganglion. This process pertains to the initial formation of a structure from unspecified parts. + dph + 2013-07-10T08:51:50Z + biological_process + ganglia formation + GO:0061554 + ganglion formation + + + + + The process that gives rise to ganglion. This process pertains to the initial formation of a structure from unspecified parts. + GOC:dph + + + + + ganglia formation + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of a trigeminal ganglion is generated and organized. + dph + 2013-07-10T08:57:12Z + biological_process + trigeminal ganglia morphogenesis + GO:0061556 + trigeminal ganglion morphogenesis + + + + + The process in which the anatomical structure of a trigeminal ganglion is generated and organized. + GOC:dph + + + + + trigeminal ganglia morphogenesis + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for a trigeminal ganglion to attain its fully functional state. + dph + 2013-07-10T08:58:24Z + biological_process + trigeminal ganglia maturation + GO:0061557 + trigeminal ganglion maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for a trigeminal ganglion to attain its fully functional state. + GOC:dph + + + + + trigeminal ganglia maturation + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for a cranial ganglion to attain its fully functional state. + dph + 2013-07-10T08:59:52Z + biological_process + cranial ganglia maturation + GO:0061558 + cranial ganglion maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for a cranial ganglion to attain its fully functional state. + GOC:dph + + + + + cranial ganglia maturation + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structure of a cranial ganglion is generated and organized. + dph + 2013-07-10T09:02:15Z + biological_process + cranial ganglia morphogenesis + GO:0061559 + cranial ganglion morphogenesis + + + + + The process in which the anatomical structure of a cranial ganglion is generated and organized. + GOC:dph + + + + + cranial ganglia morphogenesis + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to a cranial ganglion. This process pertains to the initial formation of a structure from unspecified parts. + dph + 2013-07-10T09:07:27Z + biological_process + cranial ganglia formation + GO:0061560 + cranial ganglion formation + + + + + The process that gives rise to a cranial ganglion. This process pertains to the initial formation of a structure from unspecified parts. + GOC:dph + + + + + cranial ganglia formation + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to the trigeminal ganglion. This process pertains to the initial formation of a structure from unspecified parts. + dph + 2013-07-10T09:08:13Z + biological_process + trigeminal ganglia formation + GO:0061561 + trigeminal ganglion formation + + + + + The process that gives rise to the trigeminal ganglion. This process pertains to the initial formation of a structure from unspecified parts. + GOC:dph + + + + + trigeminal ganglia formation + GOC:dph + + + + + + + + + The progression of an axon over time. Covers axonogenesis (de novo generation of an axon) and axon regeneration (regrowth), as well as processes pertaining to the progression of the axon over time (fasciculation and defasciculation). + dph + 2013-07-18T14:43:01Z + biological_process + GO:0061564 + axon development + + + + + The progression of an axon over time. Covers axonogenesis (de novo generation of an axon) and axon regeneration (regrowth), as well as processes pertaining to the progression of the axon over time (fasciculation and defasciculation). + GOC:dph + GOC:pg + GOC:pr + + + + + + + + + + + + + + + + + + + + A process that results in the assembly, arrangement of constituent parts, or disassembly of an actin filament bundle. + dph + 2013-08-02T11:24:11Z + biological_process + actin filament cable organization + GO:0061572 + actin filament bundle organization + + + + + A process that results in the assembly, arrangement of constituent parts, or disassembly of an actin filament bundle. + GOC:dph + + + + + actin filament cable organization + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of a pharyngeal arch artery is generated and organized. The pharyngeal arch arteries are a series of six paired embryological vascular structures, the development of which give rise to several major arteries, such as the stapedial artery, the middle meningeal artery, the internal carotid artery and the pulmonary artery. + dph + 2014-05-09T15:34:06Z + aortic arch artery morphogenesis + biological_process + GO:0061626 + pharyngeal arch artery morphogenesis + + + + + The process in which the anatomical structures of a pharyngeal arch artery is generated and organized. The pharyngeal arch arteries are a series of six paired embryological vascular structures, the development of which give rise to several major arteries, such as the stapedial artery, the middle meningeal artery, the internal carotid artery and the pulmonary artery. + GOC:BHF + GOC:dph + PMID:20122914 + + + + + aortic arch artery morphogenesis + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of a seminal vesicle are generated and organized. + dph + 2015-03-04T13:33:49Z + biological_process + GO:0061682 + seminal vesicle morphogenesis + + + + + The process in which the anatomical structures of a seminal vesicle are generated and organized. + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the branching structure of the seminal vesicle is generated and organized. A branch is a division or offshoot from a main stem. + dph + 2015-03-04T13:39:47Z + gonecyst branching morphogenesis + seminal gland branching morphogenesis + seminal vesicle branching + seminal vesicle branching morphogenesis + biological_process + GO:0061683 + branching involved in seminal vesicle morphogenesis + + + + + The process in which the branching structure of the seminal vesicle is generated and organized. A branch is a division or offshoot from a main stem. + GOC:dph + PMID:16916376 + + + + + gonecyst branching morphogenesis + GOC:dph + + + + + seminal gland branching morphogenesis + GOC:dph + + + + + seminal vesicle branching + GOC:dph + + + + + seminal vesicle branching morphogenesis + GOC:dph + + + + + + + + + + + + + + + + + + + + A transferase complex capable of catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor). + dph + 2015-05-06T11:22:38Z + cellular_component + GO:0061695 + transferase complex, transferring phosphorus-containing groups + + + + + A transferase complex capable of catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor). + GOC:bhm + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + The step in the formation of the neural tube, where the paired anterior neural folds are brought together and fuse at the dorsal midline. + dph + 2015-06-23T10:13:41Z + biological_process + GO:0061713 + anterior neural tube closure + + + + + The step in the formation of the neural tube, where the paired anterior neural folds are brought together and fuse at the dorsal midline. + GOC:BHF + GOC:dph + GOC:hal + PMID:17286298 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of neuroblast migration. + dph + 2017-03-08T18:17:07Z + biological_process + GO:0061853 + regulation of neuroblast migration + + + + + Any process that modulates the frequency, rate or extent of neuroblast migration. + PMID:23149556 + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of neuroblast migration. + dph + 2017-03-08T18:22:30Z + biological_process + GO:0061854 + positive regulation of neuroblast migration + + + + + Any process that activates or increases the frequency, rate or extent of neuroblast migration. + PMID:23149556 + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of neuroblast migration. + dph + 2017-03-08T18:26:21Z + biological_process + GO:0061855 + negative regulation of neuroblast migration + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of neuroblast migration. + PMID:23149556 + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of astrocyte activation. + dph + 2017-06-01T22:26:29Z + biological_process + GO:0061888 + regulation of astrocyte activation + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate or extent of astrocyte activation. + GOC:aruk + GOC:bc + PMID:20005821 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Any process that decreases the frequency, rate or extent of astrocyte activation. + dph + 2017-06-01T22:29:43Z + biological_process + GO:0061889 + negative regulation of astrocyte activation + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that decreases the frequency, rate or extent of astrocyte activation. + GOC:aruk + GOC:bc + PMID:20005821 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Any process that increases the frequency, rate or extent of astrocyte activation. + dph + 2017-06-01T22:31:50Z + biological_process + GO:0061890 + positive regulation of astrocyte activation + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that increases the frequency, rate or extent of astrocyte activation. + GOC:aruk + GOC:bc + PMID:20005821 + + + + + + + + + + + + + + + + + + + + + + + + + A change in morphology and behavior of a glial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. + dph + 2017-06-13T13:06:23Z + biological_process + GO:0061900 + glial cell activation + + + + + A change in morphology and behavior of a glial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor. + GOC:aruk + GOC:bc + PMID:18723082 + + + + + + + + + + + + + + + + + + + A process in which a protein is transported to or maintained in a location within the somatodendritic compartment. + dph + 2017-09-08T13:22:26Z + somatodendritic protein localization + biological_process + GO:0061938 + protein localization to somatodendritic compartment + + + + + A process in which a protein is transported to or maintained in a location within the somatodendritic compartment. + PMID:18341993 + + + + + + + + + + + + + + + + + + + + + + + The directed movement of a protein to a specific location in a plasma membrane. + dph + 2017-10-26T12:55:15Z + biological_process + GO:0061951 + establishment of protein localization to plasma membrane + + + + + The directed movement of a protein to a specific location in a plasma membrane. + GOC:dph + GOC:vw + + + + + + + + + + + + + + + + + + + + The process in which bones are generated and organized as a result of the conversion of another structural tissue into bone. + dph + 2018-02-12T18:10:59Z + biological_process + GO:0061971 + replacement bone morphogenesis + + + + + The process in which bones are generated and organized as a result of the conversion of another structural tissue into bone. + DOI:10.1002/(SICI)1097-4687(199608)229:2<121::AID-JMOR1>3.0.CO;2-4 + + + + + + + + + + + + + + + + + + + The process in which bone which forms superficially in the organism are generated and organized. + dph + 2018-02-12T18:16:21Z + biological_process + GO:0061972 + dermal bone morphogenesis + + + + + The process in which bone which forms superficially in the organism are generated and organized. + PMID:12588850 + PMID:15003632 + + + + + + + + + + + + + + + + + + + The process in which bone which forms deep in the organism are generated and organized. + dph + 2018-02-12T18:21:09Z + biological_process + GO:0061973 + membrane bone morphogenesis + + + + + The process in which bone which forms deep in the organism are generated and organized. + PMID:14579374 + + + + + + + + + + + + + + + + + + + The process in which bones are generated and organized as a result of the conversion of initial connective tissue surrounding cartilage into bone. + dph + 2018-02-12T18:26:10Z + biological_process + GO:0061974 + perichondral bone morphogenesis + + + + + The process in which bones are generated and organized as a result of the conversion of initial connective tissue surrounding cartilage into bone. + PMID:21901110 + + + + + + + + + + + + + + + + + + + The biological process whose specific outcome is the progression of the secondary palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The secondary palate is the part of the palate formed from the fusion of the two palatine shelves, extensions of the maxillary prominences. + dph + 2018-02-26T22:55:20Z + biological_process + GO:0062009 + secondary palate development + + + + + The biological process whose specific outcome is the progression of the secondary palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The secondary palate is the part of the palate formed from the fusion of the two palatine shelves, extensions of the maxillary prominences. + PMID:28784960 + + + + + + + + + + + + + + + + + + + The biological process whose specific outcome is the progression of the primitive palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. + dph + 2018-02-26T23:00:48Z + biological_process + GO:0062010 + primitive palate development + + + + + The biological process whose specific outcome is the progression of the primitive palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. + GOC:dph + + + + + + + + + + + + + + + + + + + Any process that modulates the rate, frequency or extent of a small molecule metabolic process. + dph + 2018-03-19T14:11:54Z + regulation of small molecule metabolism + biological_process + GO:0062012 + regulation of small molecule metabolic process + + + + + Any process that modulates the rate, frequency or extent of a small molecule metabolic process. + GOC:vw + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of a small molecule metabolic process. + dph + 2018-03-19T14:25:10Z + positive regulation of small molecule metabolism + biological_process + GO:0062013 + positive regulation of small molecule metabolic process + + + + + Any process that activates or increases the frequency, rate or extent of a small molecule metabolic process. + GOC:vw + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of a small molecule metabolic process. + dph + 2018-03-19T14:27:23Z + negative regulation of small molecule metabolism + biological_process + GO:0062014 + negative regulation of small molecule metabolic process + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of a small molecule metabolic process. + GOC:vw + + + + + + + + + + + + + + + + + + + + + An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells. + dph + 2018-04-13T12:47:21Z + cellular_component + GO:0062023 + collagen-containing extracellular matrix + + + + + An extracellular matrix consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that provides not only essential physical scaffolding for the cellular constituents but can also initiate crucial biochemical and biomechanical cues required for tissue morphogenesis, differentiation and homeostasis. The components are secreted by cells in the vicinity and form a sheet underlying or overlying cells such as endothelial and epithelial cells. + GOC:BHF + GOC:rph + PMID:21123617 + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the stomach over time, from its formation to the mature structure. The stomach is an expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ. + dph + 2018-11-20T18:15:45Z + biological_process + GO:0062094 + stomach development + + + + + The process whose specific outcome is the progression of the stomach over time, from its formation to the mature structure. The stomach is an expanded region of the vertebrate alimentary tract that serves as a food storage compartment and digestive organ. + PMID:11967278 + + + + + + + + + + + + + + + + + + + The series of events involved in the perception of pain in which a stimulus is received and converted into a molecular signal. + dph + 2019-09-13T13:48:47Z + biological_process + GO:0062149 + detection of stimulus involved in sensory perception of pain + + + + + The series of events involved in the perception of pain in which a stimulus is received and converted into a molecular signal. + PMID:19837031 + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform lutein. + dph + 2019-11-18T15:56:36Z + lutein metabolism + biological_process + GO:0062170 + lutein metabolic process + + + + + The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform lutein. + PMID:24397433 + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of lutein. + dph + 2019-11-18T16:01:00Z + lutein anabolism + lutein biosynthesis + lutein formation + biological_process + GO:0062171 + lutein biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of lutein. + PMID:24397433 + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of lutein. + dph + 2019-11-18T16:06:07Z + lutein breakdown + lutein catabolism + lutein degradation + biological_process + GO:0062172 + lutein catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of lutein. + PMID:24397433 + + + + + + + + + + + + + + + + + + + Any process that regulates the rate, frequency or extent of somatic muscle development. + dph + 2020-03-13T18:58:37Z + biological_process + GO:0062223 + regulation of somatic muscle development + + + + + Any process that regulates the rate, frequency or extent of somatic muscle development. + PMID:16643882 + PMID:25758712 + + + + + + + + + + + + + + + + + + + Any process that increases the rate, frequency or extent of somatic muscle development. + dph + 2020-03-13T19:03:38Z + biological_process + GO:0062224 + positive regulation of somatic muscle development + + + + + Any process that increases the rate, frequency or extent of somatic muscle development. + PMID:16643882 + PMID:25758712 + + + + + + + + + + + + + + + + + + + Any process that decreases the rate, frequency or extent of somatic muscle development. + dph + 2020-03-13T19:06:27Z + biological_process + GO:0062225 + negative regulation of somatic muscle development + + + + + Any process that decreases the rate, frequency or extent of somatic muscle development. + PMID:16643882 + PMID:25758712 + + + + + + + + + + + + + + + + + + + + The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex. + https://github.com/geneontology/go-ontology/issues/22580 + GO:0006461 + GO:0034622 + GO:0043623 + cellular protein complex assembly + biological_process + cellular macromolecule complex assembly + cellular protein-containing complex assembly + chaperone activity + macromolecular complex assembly + macromolecule complex assembly + protein complex assembly + protein complex formation + GO:0065003 + + + + + + + + protein-containing complex assembly + + + + + The aggregation, arrangement and bonding together of a set of macromolecules to form a protein-containing complex. + GOC:jl + + + + + + + + + Any process that modulates a measurable attribute of any biological process, quality or function. + regulation + biological_process + GO:0065007 + + + biological regulation + + + + + Any process that modulates a measurable attribute of any biological process, quality or function. + GOC:dph + GOC:isa_complete + GOC:mah + GOC:pr + GOC:vw + + + + + + + + + + + + + + + + + + + + Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc. + regulation of biological attribute + regulation of biological characteristic + biological_process + GO:0065008 + + regulation of biological quality + + + + + Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc. + GOC:dph + GOC:isa_complete + GOC:mah + GOC:pr + GOC:vw + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. + regulation of a molecular function + biological_process + GO:0065009 + + + + regulation of molecular function + + + + + Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding. + GOC:isa_complete + + + + + + + + + + + + + + + + + + + + + Organized structure of distinctive morphology and function, bounded by a lipid bilayer membrane and occurring outside the cell. + extracellular membrane-enclosed organelle + cellular_component + GO:0065010 + extracellular membrane-bounded organelle + + + + + Organized structure of distinctive morphology and function, bounded by a lipid bilayer membrane and occurring outside the cell. + GOC:isa_complete + + + + + + + + + + + + + + + + + + + + + The cellular homeostatic process that preserves a neuron in a stable, differentiated functional and structural state. + neuron maintenance + biological_process + GO:0070050 + neuron cellular homeostasis + + + + + The cellular homeostatic process that preserves a neuron in a stable, differentiated functional and structural state. + GOC:BHF + GOC:mah + + + + + + + + + + + + + + + + + + + + Binding to fibrinogen, a highly soluble hexameric glycoprotein complex that is found in blood plasma and is converted to fibrin by thrombin in the coagulation cascade. + molecular_function + GO:0070051 + fibrinogen binding + + + + + Binding to fibrinogen, a highly soluble hexameric glycoprotein complex that is found in blood plasma and is converted to fibrin by thrombin in the coagulation cascade. + GOC:BHF + GOC:mah + GOC:vk + + + + + + + + + + + + + + + + + + + + The regulated release of glucagon from secretory granules in the A (alpha) cells of the pancreas (islets of Langerhans). + biological_process + GO:0070091 + glucagon secretion + + + + + The regulated release of glucagon from secretory granules in the A (alpha) cells of the pancreas (islets of Langerhans). + GOC:BHF + GOC:rl + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the regulated release of glucagon. + biological_process + GO:0070092 + regulation of glucagon secretion + + + + + Any process that modulates the frequency, rate or extent of the regulated release of glucagon. + GOC:BHF + GOC:mah + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of glucagon. + down regulation of glucagon secretion + down-regulation of glucagon secretion + downregulation of glucagon secretion + inhibition of glucagon secretion + biological_process + GO:0070093 + negative regulation of glucagon secretion + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of glucagon. + GOC:BHF + GOC:mah + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the regulated release of glucagon. + up regulation of glucagon secretion + up-regulation of glucagon secretion + upregulation of glucagon secretion + activation of glucagon secretion + stimulation of glucagon secretion + biological_process + GO:0070094 + positive regulation of glucagon secretion + + + + + Any process that activates or increases the frequency, rate or extent of the regulated release of glucagon. + GOC:BHF + GOC:mah + + + + + + + + + + + + + + + + + + + + + The progression of the Kupffer's vesicle over time from its initial formation until its mature state. The Kupffer's vesicle is a small but distinctive epithelial sac containing fluid, located midventrally posterior to the yolk cell or its extension, and transiently present during most of the segmentation period. + KV development + biological_process + GO:0070121 + Kupffer's vesicle development + + + + + The progression of the Kupffer's vesicle over time from its initial formation until its mature state. The Kupffer's vesicle is a small but distinctive epithelial sac containing fluid, located midventrally posterior to the yolk cell or its extension, and transiently present during most of the segmentation period. + GOC:dgh + + + + + KV development + GOC:dgh + + + + + + + + + A cell-cell junction that seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other. + Wikipedia:Tight_junction + occluding cell junction + occluding junction + cellular_component + GO:0070160 + tight junction + + + + + A cell-cell junction that seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other. + ISBN:0815332181 + + + + + occluding cell junction + GOC:mah + + + + + occluding junction + GOC:mah + + + + + + + + + A cell junction that mechanically attaches a cell (and its cytoskeleton) to neighboring cells or to the extracellular matrix. + anchoring cell junction + cellular_component + GO:0070161 + anchoring junction + + + + + A cell junction that mechanically attaches a cell (and its cytoskeleton) to neighboring cells or to the extracellular matrix. + ISBN:0815332181 + + + + + anchoring cell junction + GOC:mah + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds. + biological_process + GO:0070167 + regulation of biomineral tissue development + + + + + Any process that modulates the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds. + biological_process + GO:0070168 + negative regulation of biomineral tissue development + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds. + biological_process + GO:0070169 + positive regulation of biomineral tissue development + + + + + Any process that activates or increases the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures. + biological_process + GO:0070170 + regulation of tooth mineralization + + + + + Any process that modulates the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures. + GOC:BHF + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures. + biological_process + GO:0070171 + negative regulation of tooth mineralization + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures. + GOC:BHF + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures. + biological_process + GO:0070172 + positive regulation of tooth mineralization + + + + + Any process that activates or increases the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures. + GOC:BHF + GOC:mah + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location. + regulation of establishment of protein localisation + biological_process + GO:0070201 + regulation of establishment of protein localization + + + + + Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location. + GOC:BHF + GOC:mah + + + + + regulation of establishment of protein localisation + GOC:mah + + + + + + + + + + + + + + + + + + + + The regulated release of somatostatin from secretory granules in the D cells of the pancreas. + biological_process + GO:0070253 + somatostatin secretion + + + + + The regulated release of somatostatin from secretory granules in the D cells of the pancreas. + GOC:mah + + + + + + + + + + + + + + + + + + + + + The regulated release of mucus by the mucosa. Mucus is a viscous slimy secretion consisting of mucins and various inorganic salts dissolved in water, with suspended epithelial cells and leukocytes. The mucosa, or mucous membrane, is the membrane covered with epithelium that lines the tubular organs of the body. Mucins are carbohydrate-rich glycoproteins that have a lubricating and protective function. + mucus production + biological_process + GO:0070254 + mucus secretion + + + + + The regulated release of mucus by the mucosa. Mucus is a viscous slimy secretion consisting of mucins and various inorganic salts dissolved in water, with suspended epithelial cells and leukocytes. The mucosa, or mucous membrane, is the membrane covered with epithelium that lines the tubular organs of the body. Mucins are carbohydrate-rich glycoproteins that have a lubricating and protective function. + GOC:add + ISBN:068340007X + ISBN:0721662544 + + + + + mucus production + GOC:add + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the regulated release of mucus from a cell or a tissue. + regulation of mucus production + biological_process + GO:0070255 + regulation of mucus secretion + + + + + Any process that modulates the frequency, rate or extent of the regulated release of mucus from a cell or a tissue. + GOC:add + + + + + regulation of mucus production + GOC:add + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of mucus from a cell or a tissue. + negative regulation of mucus production + biological_process + GO:0070256 + negative regulation of mucus secretion + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of mucus from a cell or a tissue. + GOC:add + + + + + negative regulation of mucus production + GOC:add + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the regulated release of mucus from a cell or a tissue. + positive regulation of mucus production + biological_process + GO:0070257 + positive regulation of mucus secretion + + + + + Any process that activates or increases the frequency, rate or extent of the regulated release of mucus from a cell or a tissue. + GOC:add + + + + + positive regulation of mucus production + GOC:add + + + + + + + + + + + + + + + The controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell. + ECM constituent secretion + ECM secretion + biological_process + GO:0070278 + extracellular matrix constituent secretion + + + + + The controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell. + GOC:mah + + + + + ECM constituent secretion + GOC:mah + + + + + ECM secretion + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a pigment cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a pigment cell fate. + biological_process + GO:0070285 + pigment cell development + + + + + The process whose specific outcome is the progression of a pigment cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a pigment cell fate. + GOC:cvs + + + + + + + + + A renal system process in which water, ions, glucose and proteins are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures (e.g. protein absorption is observed in nephrocytes in Drosophila, see PMID:23264686). + nephron absorption + renal reabsorption + biological_process + GO:0070293 + renal absorption + + + + + A renal system process in which water, ions, glucose and proteins are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures (e.g. protein absorption is observed in nephrocytes in Drosophila, see PMID:23264686). + GOC:dph + GOC:mah + GOC:yaf + + + + + nephron absorption + GOC:mah + + + + + renal reabsorption + GOC:dph + + + + + + + + + + A renal system process in which water is taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures. + nephron water absorption + renal water reabsorption + biological_process + GO:0070295 + renal water absorption + + + + + A renal system process in which water is taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures. + GOC:dph + GOC:mah + + + + + nephron water absorption + GOC:mah + + + + + renal water reabsorption + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of a lens fiber cell, any of the elongated, tightly packed cells that make up the bulk of the mature lens in the camera-type eye. The cytoplasm of a lens fiber cell is devoid of most intracellular organelles including the cell nucleus, and contains primarily crystallins, a group of water-soluble proteins expressed in vary large quantities. + lens fibre cell differentiation + biological_process + GO:0070306 + lens fiber cell differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized features of a lens fiber cell, any of the elongated, tightly packed cells that make up the bulk of the mature lens in the camera-type eye. The cytoplasm of a lens fiber cell is devoid of most intracellular organelles including the cell nucleus, and contains primarily crystallins, a group of water-soluble proteins expressed in vary large quantities. + GOC:mah + PMID:7693735 + + + + + lens fibre cell differentiation + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a lens fiber cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a lens fiber cell fate. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye. + lens fibre cell development + biological_process + GO:0070307 + lens fiber cell development + + + + + The process whose specific outcome is the progression of a lens fiber cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a lens fiber cell fate. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye. + GOC:mah + PMID:7693735 + + + + + lens fibre cell development + GOC:mah + + + + + + + + + + + + + + + + + + + + Binding to thyroxine (T4) or triiodothyronine (T3), tyrosine-based hormones produced by the thyroid gland. + thyroxine binding + triiodothyronine binding + molecular_function + GO:0070324 + + thyroid hormone binding + + + + + Binding to thyroxine (T4) or triiodothyronine (T3), tyrosine-based hormones produced by the thyroid gland. + GOC:rph + + + + + thyroxine binding + GOC:mah + + + + + triiodothyronine binding + GOC:mah + + + + + + + + + + + + + + + + + + + + The directed movement of thyroid hormone into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + thyroxine transport + triiodothyronine transport + biological_process + GO:0070327 + thyroid hormone transport + + + + + The directed movement of thyroid hormone into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:rph + + + + + thyroxine transport + GOC:mah + + + + + triiodothyronine transport + GOC:mah + + + + + + + + + + + + + + + + + + + + The multiplication or reproduction of fat cells by cell division, resulting in the expansion of their population. A fat cell is an animal connective tissue cell specialized for the synthesis and storage of fat. + adipocyte proliferation + adipose cell proliferation + biological_process + GO:0070341 + fat cell proliferation + + + + + The multiplication or reproduction of fat cells by cell division, resulting in the expansion of their population. A fat cell is an animal connective tissue cell specialized for the synthesis and storage of fat. + GOC:mah + GOC:sl + + + + + adipocyte proliferation + GOC:sl + + + + + adipose cell proliferation + GOC:sl + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The multiplication or reproduction of brown fat cells by cell division, resulting in the expansion of their population. A brown fat cell is a fat cell found the thermogenic form of adipose tissue found in newborns of many species. + + brown adipocyte proliferation + brown adipose cell proliferation + biological_process + GO:0070342 + brown fat cell proliferation + + + + + The multiplication or reproduction of brown fat cells by cell division, resulting in the expansion of their population. A brown fat cell is a fat cell found the thermogenic form of adipose tissue found in newborns of many species. + CL:0000449 + GOC:mah + GOC:sl + + + + + brown adipocyte proliferation + GOC:sl + + + + + brown adipose cell proliferation + GOC:sl + + + + + + + + + + + + + + + + + + + + The multiplication or reproduction of white fat cells by cell division, resulting in the expansion of their population. + white adipocyte proliferation + white adipose cell proliferation + biological_process + GO:0070343 + white fat cell proliferation + + + + + The multiplication or reproduction of white fat cells by cell division, resulting in the expansion of their population. + CL:0000448 + GOC:mah + GOC:sl + + + + + white adipocyte proliferation + GOC:sl + + + + + white adipose cell proliferation + GOC:sl + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of fat cell proliferation. + regulation of adipocyte proliferation + regulation of adipose cell proliferation + biological_process + GO:0070344 + regulation of fat cell proliferation + + + + + Any process that modulates the frequency, rate or extent of fat cell proliferation. + GOC:mah + GOC:sl + + + + + regulation of adipocyte proliferation + GOC:sl + + + + + regulation of adipose cell proliferation + GOC:sl + + + + + + + + + + + + + + + + + + + Any process that stops or decreases the rate or extent of fat cell proliferation. + down regulation of fat cell proliferation + down-regulation of fat cell proliferation + downregulation of fat cell proliferation + negative regulation of adipocyte proliferation + negative regulation of adipose cell proliferation + inhibition of fat cell proliferation + biological_process + GO:0070345 + negative regulation of fat cell proliferation + + + + + Any process that stops or decreases the rate or extent of fat cell proliferation. + GOC:mah + GOC:sl + + + + + down regulation of fat cell proliferation + GOC:mah + + + + + down-regulation of fat cell proliferation + GOC:mah + + + + + downregulation of fat cell proliferation + GOC:mah + + + + + negative regulation of adipocyte proliferation + GOC:sl + + + + + negative regulation of adipose cell proliferation + GOC:sl + + + + + inhibition of fat cell proliferation + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that activates or increases the rate or extent of fat cell proliferation. + positive regulation of adipocyte proliferation + positive regulation of adipose cell proliferation + up regulation of fat cell proliferation + up-regulation of fat cell proliferation + upregulation of fat cell proliferation + activation of fat cell proliferation + stimulation of fat cell proliferation + biological_process + GO:0070346 + positive regulation of fat cell proliferation + + + + + Any process that activates or increases the rate or extent of fat cell proliferation. + GOC:mah + GOC:sl + + + + + positive regulation of adipocyte proliferation + GOC:sl + + + + + positive regulation of adipose cell proliferation + GOC:sl + + + + + up regulation of fat cell proliferation + GOC:mah + + + + + up-regulation of fat cell proliferation + GOC:mah + + + + + upregulation of fat cell proliferation + GOC:mah + + + + + activation of fat cell proliferation + GOC:mah + + + + + stimulation of fat cell proliferation + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of brown fat cell proliferation. + regulation of brown adipocyte proliferation + regulation of brown adipose cell proliferation + biological_process + GO:0070347 + regulation of brown fat cell proliferation + + + + + Any process that modulates the frequency, rate or extent of brown fat cell proliferation. + GOC:mah + GOC:sl + + + + + regulation of brown adipocyte proliferation + GOC:sl + + + + + regulation of brown adipose cell proliferation + GOC:sl + + + + + + + + + + + + + + + + + + + Any process that stops or decreases the rate or extent of brown fat cell proliferation. + down regulation of brown fat cell proliferation + down-regulation of brown fat cell proliferation + downregulation of brown fat cell proliferation + negative regulation of brown adipocyte proliferation + negative regulation of brown adipose cell proliferation + inhibition of brown fat cell proliferation + biological_process + GO:0070348 + negative regulation of brown fat cell proliferation + + + + + Any process that stops or decreases the rate or extent of brown fat cell proliferation. + GOC:mah + GOC:sl + + + + + down regulation of brown fat cell proliferation + GOC:mah + + + + + down-regulation of brown fat cell proliferation + GOC:mah + + + + + downregulation of brown fat cell proliferation + GOC:mah + + + + + negative regulation of brown adipocyte proliferation + GOC:sl + + + + + negative regulation of brown adipose cell proliferation + GOC:sl + + + + + inhibition of brown fat cell proliferation + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that activates or increases the rate or extent of brown fat cell proliferation. + positive regulation of brown adipocyte proliferation + positive regulation of brown adipose cell proliferation + up regulation of brown fat cell proliferation + up-regulation of brown fat cell proliferation + upregulation of brown fat cell proliferation + activation of brown fat cell proliferation + stimulation of brown fat cell proliferation + biological_process + GO:0070349 + positive regulation of brown fat cell proliferation + + + + + Any process that activates or increases the rate or extent of brown fat cell proliferation. + GOC:mah + GOC:sl + + + + + positive regulation of brown adipocyte proliferation + GOC:sl + + + + + positive regulation of brown adipose cell proliferation + GOC:sl + + + + + up regulation of brown fat cell proliferation + GOC:mah + + + + + up-regulation of brown fat cell proliferation + GOC:mah + + + + + upregulation of brown fat cell proliferation + GOC:mah + + + + + activation of brown fat cell proliferation + GOC:mah + + + + + stimulation of brown fat cell proliferation + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of white fat cell proliferation. + regulation of white adipocyte proliferation + regulation of white adipose cell proliferation + biological_process + GO:0070350 + regulation of white fat cell proliferation + + + + + Any process that modulates the frequency, rate or extent of white fat cell proliferation. + GOC:mah + GOC:sl + + + + + regulation of white adipocyte proliferation + GOC:sl + + + + + regulation of white adipose cell proliferation + GOC:sl + + + + + + + + + + + + + + + + + + + Any process that stops or decreases the rate or extent of white fat cell proliferation. + down regulation of white fat cell proliferation + down-regulation of white fat cell proliferation + downregulation of white fat cell proliferation + negative regulation of white adipocyte proliferation + negative regulation of white adipose cell proliferation + inhibition of white fat cell proliferation + biological_process + GO:0070351 + negative regulation of white fat cell proliferation + + + + + Any process that stops or decreases the rate or extent of white fat cell proliferation. + GOC:mah + GOC:sl + + + + + down regulation of white fat cell proliferation + GOC:mah + + + + + down-regulation of white fat cell proliferation + GOC:mah + + + + + downregulation of white fat cell proliferation + GOC:mah + + + + + negative regulation of white adipocyte proliferation + GOC:sl + + + + + negative regulation of white adipose cell proliferation + GOC:sl + + + + + inhibition of white fat cell proliferation + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that activates or increases the rate or extent of white fat cell proliferation. + positive regulation of white adipocyte proliferation + positive regulation of white adipose cell proliferation + up regulation of white fat cell proliferation + up-regulation of white fat cell proliferation + upregulation of white fat cell proliferation + activation of white fat cell proliferation + stimulation of white fat cell proliferation + biological_process + GO:0070352 + positive regulation of white fat cell proliferation + + + + + Any process that activates or increases the rate or extent of white fat cell proliferation. + GOC:mah + GOC:sl + + + + + positive regulation of white adipocyte proliferation + GOC:sl + + + + + positive regulation of white adipose cell proliferation + GOC:sl + + + + + up regulation of white fat cell proliferation + GOC:mah + + + + + up-regulation of white fat cell proliferation + GOC:mah + + + + + upregulation of white fat cell proliferation + GOC:mah + + + + + activation of white fat cell proliferation + GOC:mah + + + + + stimulation of white fat cell proliferation + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires the specialized features of a hepatocyte. A hepatocyte is specialized epithelial cell that is organized into interconnected plates called lobules, and is the main structural component of the liver. + liver cell differentiation + biological_process + GO:0070365 + hepatocyte differentiation + + + + + The process in which a relatively unspecialized cell acquires the specialized features of a hepatocyte. A hepatocyte is specialized epithelial cell that is organized into interconnected plates called lobules, and is the main structural component of the liver. + CL:0000182 + PMID:7588884 + + + + + liver cell differentiation + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of hepatocyte differentiation. + regulation of liver cell differentiation + biological_process + GO:0070366 + regulation of hepatocyte differentiation + + + + + Any process that modulates the frequency, rate or extent of hepatocyte differentiation. + GOC:mah + GOC:sl + + + + + regulation of liver cell differentiation + GOC:sl + + + + + + + + + + + + + + + + + + + + Any process that stops or decreases the rate or extent of hepatocyte differentiation. + down regulation of hepatocyte differentiation + down-regulation of hepatocyte differentiation + downregulation of hepatocyte differentiation + negative regulation of liver cell differentiation + inhibition of hepatocyte differentiation + biological_process + GO:0070367 + negative regulation of hepatocyte differentiation + + + + + Any process that stops or decreases the rate or extent of hepatocyte differentiation. + GOC:mah + GOC:sl + + + + + down regulation of hepatocyte differentiation + GOC:mah + + + + + down-regulation of hepatocyte differentiation + GOC:mah + + + + + downregulation of hepatocyte differentiation + GOC:mah + + + + + negative regulation of liver cell differentiation + GOC:sl + + + + + inhibition of hepatocyte differentiation + GOC:mah + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the rate or extent of hepatocyte differentiation. + positive regulation of liver cell differentiation + up regulation of hepatocyte differentiation + up-regulation of hepatocyte differentiation + upregulation of hepatocyte differentiation + activation of hepatocyte differentiation + stimulation of hepatocyte differentiation + biological_process + GO:0070368 + positive regulation of hepatocyte differentiation + + + + + Any process that activates or increases the rate or extent of hepatocyte differentiation. + GOC:mah + GOC:sl + + + + + positive regulation of liver cell differentiation + GOC:sl + + + + + up regulation of hepatocyte differentiation + GOC:mah + + + + + up-regulation of hepatocyte differentiation + GOC:mah + + + + + upregulation of hepatocyte differentiation + GOC:mah + + + + + activation of hepatocyte differentiation + GOC:mah + + + + + stimulation of hepatocyte differentiation + GOC:mah + + + + + + + + + + + + + + + + + + + + A transport vesicle that mediates transport from an intracellular compartment to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis. + exocytic constitutive secretory pathway transport vesicle + exocytotic vesicle + cellular_component + GO:0070382 + exocytic vesicle + + + + + A transport vesicle that mediates transport from an intracellular compartment to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis. + GOC:kad + GOC:mah + + + + + exocytotic vesicle + GOC:kad + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the Harderian gland over time, from its formation to the mature structure. The Harderian gland is an anterior orbital structure usually associated with the nictitating membrane, and produces and secretes a variety of substances to the eye, depending upon the species. + biological_process + GO:0070384 + Note that the Harderian gland is found in all terrestrial vertebrate groups, including amphibia, reptiles, birds, and mammals. However, it appears to be absent in certain mammals such as bats, cows, horses, and higher primates. Though largely absent in the adult human, it is present in the fetal and neonatal stages. + Harderian gland development + + + + + The process whose specific outcome is the progression of the Harderian gland over time, from its formation to the mature structure. The Harderian gland is an anterior orbital structure usually associated with the nictitating membrane, and produces and secretes a variety of substances to the eye, depending upon the species. + GOC:hjd + PMID:16856596 + PMID:7559104 + + + + + + + + + + + + + + + + + + + Binding to ammonium ions (NH4+). + molecular_function + ammonium binding + GO:0070405 + ammonium ion binding + + + + + Binding to ammonium ions (NH4+). + CHEBI:28938 + GOC:ecd + + + + + + + + + A long, thin cell projection that contains F-actin and tubulin, with microtubules centrally located and F-actin peripherally located. + Wikipedia:Membrane_nanotube + non-sensory hair + imaginal disc-derived wing hair + cellular_component + GO:0070451 + cell hair + + + + + A long, thin cell projection that contains F-actin and tubulin, with microtubules centrally located and F-actin peripherally located. + PMID:11526084 + + + + + non-sensory hair + GOC:bf + + + + + imaginal disc-derived wing hair + GOC:mah + + + + + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen. + biological_process + GO:0070482 + response to oxygen levels + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen. + GOC:BHF + GOC:mah + + + + + + + + + + The series of events in which a stimulus indicating lowered oxygen tension is received by a cell and converted into a molecular signal. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. + detection of reduced oxygen levels + biological_process + GO:0070483 + detection of hypoxia + + + + + The series of events in which a stimulus indicating lowered oxygen tension is received by a cell and converted into a molecular signal. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. + GOC:BHF + GOC:mah + + + + + detection of reduced oxygen levels + GOC:vk + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins. + regulation of microtubule cytoskeleton organisation + regulation of microtubule dynamics + biological_process + GO:0070507 + regulation of microtubule cytoskeleton organization + + + + + Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins. + GOC:mah + + + + + regulation of microtubule cytoskeleton organisation + GOC:mah + + + + + regulation of microtubule dynamics + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + + + + + + + The regulated release of proteins by a platelet or group of platelets. + mah + 2009-04-09T02:38:05Z + biological_process + GO:0070560 + protein secretion by platelet + + + + + The regulated release of proteins by a platelet or group of platelets. + GOC:BHF + GOC:mah + + + + + + + + + + + + + + + + + + + + The expansion of a leukocyte population by cell division. + mah + 2009-05-28T05:25:28Z + biological_process + GO:0070661 + leukocyte proliferation + + + + + The expansion of a leukocyte population by cell division. + GOC:add + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of leukocyte proliferation. + mah + 2009-05-28T05:30:39Z + biological_process + GO:0070663 + regulation of leukocyte proliferation + + + + + Any process that modulates the frequency, rate or extent of leukocyte proliferation. + GOC:add + GOC:mah + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte proliferation. + mah + 2009-05-28T05:34:50Z + down regulation of leukocyte proliferation + down-regulation of leukocyte proliferation + downregulation of leukocyte proliferation + inhibition of leukocyte proliferation + biological_process + GO:0070664 + negative regulation of leukocyte proliferation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte proliferation. + GOC:add + GOC:mah + + + + + down regulation of leukocyte proliferation + GOC:mah + + + + + down-regulation of leukocyte proliferation + GOC:mah + + + + + downregulation of leukocyte proliferation + GOC:mah + + + + + inhibition of leukocyte proliferation + GOC:mah + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of leukocyte proliferation. + mah + 2009-05-28T05:36:46Z + up regulation of leukocyte proliferation + up-regulation of leukocyte proliferation + upregulation of leukocyte proliferation + activation of leukocyte proliferation + stimulation of leukocyte proliferation + biological_process + GO:0070665 + positive regulation of leukocyte proliferation + + + + + Any process that activates or increases the frequency, rate or extent of leukocyte proliferation. + GOC:add + GOC:mah + + + + + up regulation of leukocyte proliferation + GOC:mah + + + + + up-regulation of leukocyte proliferation + GOC:mah + + + + + upregulation of leukocyte proliferation + GOC:mah + + + + + activation of leukocyte proliferation + GOC:mah + + + + + stimulation of leukocyte proliferation + GOC:mah + + + + + + + + + + Any process in which a macromolecule is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell. + mah + 2009-06-16T04:08:29Z + cellular macromolecule localisation + biological_process + GO:0070727 + cellular macromolecule localization + + + + + Any process in which a macromolecule is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell. + GOC:mah + + + + + cellular macromolecule localisation + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + The aggregation, arrangement and bonding together of a set of components to form a tight junction, an occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet. + mah + 2009-07-23T04:32:38Z + tight junction formation + biological_process + GO:0070830 + bicellular tight junction assembly + + + + + The aggregation, arrangement and bonding together of a set of components to form a tight junction, an occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet. + GOC:mah + + + + + tight junction formation + GOC:mah + + + + + + + + + + + + + + + + + + + The aggregation, arrangement and bonding together of a set of components to form a basement membrane, a part of the extracellular region that consists of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. + mah + 2009-07-23T05:01:51Z + biological_process + GO:0070831 + Note that this term has no relationship to 'membrane assembly ; GO:0071709' because the basement membrane is not a lipid bilayer. + basement membrane assembly + + + + + The aggregation, arrangement and bonding together of a set of components to form a basement membrane, a part of the extracellular region that consists of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids. + mah + 2009-08-14T03:09:02Z + regulation of bile acid anabolism + regulation of bile acid biosynthesis + regulation of bile acid formation + regulation of bile acid synthesis + biological_process + GO:0070857 + regulation of bile acid biosynthetic process + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids. + GOC:BHF + GOC:mah + + + + + regulation of bile acid anabolism + GOC:mah + + + + + regulation of bile acid biosynthesis + GOC:mah + + + + + regulation of bile acid formation + GOC:mah + + + + + regulation of bile acid synthesis + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids. + mah + 2009-08-14T03:16:40Z + down regulation of bile acid biosynthetic process + down-regulation of bile acid biosynthetic process + downregulation of bile acid biosynthetic process + negative regulation of bile acid anabolism + negative regulation of bile acid biosynthesis + negative regulation of bile acid formation + negative regulation of bile acid synthesis + inhibition of bile acid biosynthetic process + biological_process + GO:0070858 + negative regulation of bile acid biosynthetic process + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids. + GOC:BHF + GOC:mah + + + + + down regulation of bile acid biosynthetic process + GOC:mah + + + + + down-regulation of bile acid biosynthetic process + GOC:mah + + + + + downregulation of bile acid biosynthetic process + GOC:mah + + + + + negative regulation of bile acid anabolism + GOC:mah + + + + + negative regulation of bile acid biosynthesis + GOC:mah + + + + + negative regulation of bile acid formation + GOC:mah + + + + + negative regulation of bile acid synthesis + GOC:mah + + + + + inhibition of bile acid biosynthetic process + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids. + mah + 2009-08-14T03:22:58Z + positive regulation of bile acid anabolism + positive regulation of bile acid biosynthesis + positive regulation of bile acid formation + positive regulation of bile acid synthesis + up regulation of bile acid biosynthetic process + up-regulation of bile acid biosynthetic process + upregulation of bile acid biosynthetic process + activation of bile acid biosynthetic process + stimulation of bile acid biosynthetic process + biological_process + GO:0070859 + positive regulation of bile acid biosynthetic process + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids. + GOC:BHF + GOC:mah + + + + + positive regulation of bile acid anabolism + GOC:mah + + + + + positive regulation of bile acid biosynthesis + GOC:mah + + + + + positive regulation of bile acid formation + GOC:mah + + + + + positive regulation of bile acid synthesis + GOC:mah + + + + + up regulation of bile acid biosynthetic process + GOC:mah + + + + + up-regulation of bile acid biosynthetic process + GOC:mah + + + + + upregulation of bile acid biosynthetic process + GOC:mah + + + + + activation of bile acid biosynthetic process + GOC:mah + + + + + stimulation of bile acid biosynthetic process + GOC:mah + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glycogen. + mah + 2009-08-20T02:44:53Z + regulation of glycogen metabolism + biological_process + GO:0070873 + regulation of glycogen metabolic process + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glycogen. + GOC:mah + + + + + regulation of glycogen metabolism + GOC:mah + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glycogen. + mah + 2009-08-20T02:50:41Z + negative regulation of glycogen metabolism + biological_process + GO:0070874 + negative regulation of glycogen metabolic process + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glycogen. + GOC:mah + + + + + negative regulation of glycogen metabolism + GOC:mah + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glycogen. + mah + 2009-08-20T02:53:55Z + positive regulation of glycogen metabolism + biological_process + GO:0070875 + positive regulation of glycogen metabolic process + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glycogen. + GOC:mah + + + + + positive regulation of glycogen metabolism + GOC:mah + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus. + mah + 2009-08-27T04:41:45Z + biological_process + GO:0070887 + + Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. + cellular response to chemical stimulus + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus. + GOC:mah + + + + + + + + + + + + + + + + + + + + The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. + mah + 2009-09-15T03:00:51Z + biological_process + GO:0070925 + + organelle assembly + + + + + The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for bone to attain its fully functional state. + mah + 2009-10-05T04:35:31Z + biological_process + GO:0070977 + bone maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for bone to attain its fully functional state. + GOC:dph + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the superior temporal gyrus over time, from its formation to the mature structure. The superior temporal gyrus is a portion of the cerebral cortex that extends from the lateral sulcus to the superior temporal sulcus. + mah + 2009-11-12T02:19:23Z + biological_process + GO:0071109 + superior temporal gyrus development + + + + + The process whose specific outcome is the progression of the superior temporal gyrus over time, from its formation to the mature structure. The superior temporal gyrus is a portion of the cerebral cortex that extends from the lateral sulcus to the superior temporal sulcus. + FMA:61905 + GOC:BHF + GOC:mah + PMID:11484000 + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus. + mah + 2009-12-03T01:02:11Z + cellular response to abiotic stress + biological_process + GO:0071214 + + Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. + cellular response to abiotic stimulus + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus. + GOC:mah + + + + + cellular response to abiotic stress + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of the dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form. + mah + 2009-12-03T02:07:23Z + cellular response to acid + biological_process + cellular response to acid anion + cellular response to oxoanion + GO:0071229 + + This term should be used to describe a response to a specific acid as a chemical. E.g., if a cell were responding to glutamate, then the response would be glutamate-specific; the cell is actually responding to the chemical structure of the anion portion of the dissociated acid. Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. If annotating experiments where an acid is playing a role as a proton donor, please annotate to GO:0071468 'cellular response to acidic pH' instead. + cellular response to acid chemical + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of the dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form. + GOC:go_curators + GOC:mah + Wikipedia:Acid + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups. + mah + 2009-12-03T02:08:11Z + cellular response to amino acid + biological_process + GO:0071230 + cellular response to amino acid stimulus + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups. + GOC:mah + + + + + cellular response to amino acid + GOC:mah + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus. + mah + 2009-12-03T02:35:49Z + biological_process + GO:0071241 + cellular response to inorganic substance + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus. + mah + 2009-12-03T02:39:40Z + GO:1903718 + cellular response to ammonia + biological_process + GO:0071242 + cellular response to ammonium ion + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium stimulus. + GOC:TermGenie + GO_REF:0000071 + PMID:23509267 + + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus. + mah + 2009-12-03T02:41:21Z + biological_process + GO:0071244 + cellular response to carbon dioxide + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus. + GOC:mah + + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus. + mah + 2009-12-03T02:46:31Z + cellular response to metal + cellular response to heavy metal + biological_process + GO:0071248 + cellular response to metal ion + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus. + GOC:mah + + + + + cellular response to metal + GOC:mah + + + + + cellular response to heavy metal + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus. + mah + 2009-12-10T03:57:22Z + cellular response to iron + biological_process + GO:0071281 + cellular response to iron ion + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus. + GOC:mah + + + + + cellular response to iron + GOC:mah + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus. + mah + 2009-12-10T04:46:04Z + biological_process + GO:0071310 + cellular response to organic substance + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus. + GOC:mah + + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus. + mah + 2009-12-10T05:13:33Z + biological_process + GO:0071322 + cellular response to carbohydrate stimulus + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chitin stimulus. + mah + 2009-12-10T05:25:54Z + biological_process + GO:0071323 + cellular response to chitin + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chitin stimulus. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus. + mah + 2009-12-10T05:27:18Z + biological_process + GO:0071326 + cellular response to monosaccharide stimulus + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus. + mah + 2009-12-10T05:37:00Z + biological_process + GO:0071331 + cellular response to hexose stimulus + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus. + GOC:mah + + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus. + mah + 2009-12-10T05:38:03Z + biological_process + GO:0071333 + cellular response to glucose stimulus + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals. + mah + 2009-12-11T03:24:18Z + cellular response to polypeptide hormone stimulus + biological_process + GO:0071375 + cellular response to peptide hormone stimulus + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals. + GOC:mah + + + + + cellular response to polypeptide hormone stimulus + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus. + mah + 2009-12-11T03:25:07Z + biological_process + GO:0071377 + cellular response to glucagon stimulus + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus. + mah + 2009-12-11T03:49:02Z + biological_process + GO:0071383 + cellular response to steroid hormone stimulus + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids. + mah + 2009-12-11T03:52:07Z + biological_process + GO:0071384 + cellular response to corticosteroid stimulus + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects. + mah + 2009-12-11T03:53:56Z + biological_process + GO:0071385 + cellular response to glucocorticoid stimulus + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mineralocorticoid stimulus. Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. Mineralocorticoids act primarily on water and electrolyte balance. + mah + 2009-12-11T03:59:02Z + biological_process + GO:0071389 + cellular response to mineralocorticoid stimulus + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mineralocorticoid stimulus. Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. Mineralocorticoids act primarily on water and electrolyte balance. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus. + mah + 2009-12-11T04:11:13Z + biological_process + GO:0071393 + cellular response to progesterone stimulus + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus. + GOC:mah + + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus. + mah + 2009-12-11T04:37:10Z + biological_process + GO:0071396 + cellular response to lipid + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus. + GOC:mah + + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus. + mah + 2009-12-14T02:55:58Z + cellular response to organic cyclic substance + biological_process + GO:0071407 + cellular response to organic cyclic compound + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus. + GOC:mah + + + + + cellular response to organic cyclic substance + GOC:mah + + + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond. + mah + 2009-12-14T04:07:27Z + cellular response to organic nitrogen + biological_process + GO:0071417 + cellular response to organonitrogen compound + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond. + GOC:mah + + + + + cellular response to organic nitrogen + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups. + mah + 2009-12-14T04:08:17Z + biological_process + GO:0071418 + cellular response to amine stimulus + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter. + mah + 2009-12-14T04:09:25Z + cellular response to histamine stimulus + biological_process + GO:0071420 + cellular response to histamine + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter. + GOC:mah + + + + + cellular response to histamine stimulus + GOC:mah + + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus. + mah + 2009-12-16T04:05:33Z + cellular pheromone response + biological_process + GO:0071444 + cellular response to pheromone + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus. + GOC:mah + + + + + cellular pheromone response + GOC:mah + + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water. + mah + 2009-12-18T11:32:44Z + biological_process + GO:0071462 + cellular response to water stimulus + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water. + GOC:mah + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism. + mah + 2009-12-18T02:25:40Z + biological_process + GO:0071495 + + Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. + cellular response to endogenous stimulus + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism. + GOC:mah + + + + + + + + + + + + + + + + + + + + The process in which a neuroblast acquires the specialized structural and functional features of a dopaminergic neuron, a neuron that secretes dopamine. + mah + 2010-01-12T02:28:44Z + biological_process + GO:0071542 + dopaminergic neuron differentiation + + + + + The process in which a neuroblast acquires the specialized structural and functional features of a dopaminergic neuron, a neuron that secretes dopamine. + GOC:rph + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the cement gland over time, from its formation to the mature structure. The cement gland is a simple mucus-secreting organ positioned at the anterior of amphibious embryos. The cement gland attaches the newly hatched embryo to a support before the hatchling can swim well or feed. + mah + 2010-01-20T04:31:04Z + biological_process + GO:0071570 + cement gland development + + + + + The process whose specific outcome is the progression of the cement gland over time, from its formation to the mature structure. The cement gland is a simple mucus-secreting organ positioned at the anterior of amphibious embryos. The cement gland attaches the newly hatched embryo to a support before the hatchling can swim well or feed. + GOC:bf + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the otic vesicle over time, from its formation to the mature structure. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear. + mah + 2010-02-04T04:07:17Z + biological_process + GO:0071599 + otic vesicle development + + + + + The process whose specific outcome is the progression of the otic vesicle over time, from its formation to the mature structure. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the otic vesicle are generated and organized. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear. + mah + 2010-02-04T04:07:27Z + biological_process + GO:0071600 + otic vesicle morphogenesis + + + + + The process in which the anatomical structures of the otic vesicle are generated and organized. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear. + GOC:mah + + + + + + + + + The behavior in which an organism produces sounds by a mechanism involving its respiratory system. + mah + 2010-02-10T11:02:58Z + vocalisation behaviour + biological_process + GO:0071625 + vocalization behavior + + + + + The behavior in which an organism produces sounds by a mechanism involving its respiratory system. + GOC:mah + + + + + vocalisation behaviour + GOC:mah + + + + + + + + + The process of biting and mashing food with the teeth prior to swallowing. + mah + 2010-02-10T11:19:48Z + chewing + biological_process + GO:0071626 + mastication + + + + + The process of biting and mashing food with the teeth prior to swallowing. + GOC:gvg + + + + + chewing + GOC:mah + + + + + + + + + + + + + + + + + + + + The movement of a mononuclear cell within or between different tissues and organs of the body. + mah + 2010-02-16T02:11:00Z + biological_process + GO:0071674 + mononuclear cell migration + + + + + The movement of a mononuclear cell within or between different tissues and organs of the body. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that modulates the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body. + mah + 2010-02-16T02:11:53Z + biological_process + GO:0071675 + regulation of mononuclear cell migration + + + + + Any process that modulates the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that decreases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body. + mah + 2010-02-16T02:13:55Z + down regulation of mononuclear cell migration + down-regulation of mononuclear cell migration + downregulation of mononuclear cell migration + inhibition of mononuclear cell migration + biological_process + GO:0071676 + negative regulation of mononuclear cell migration + + + + + Any process that decreases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body. + GOC:mah + + + + + down regulation of mononuclear cell migration + GOC:mah + + + + + down-regulation of mononuclear cell migration + GOC:mah + + + + + downregulation of mononuclear cell migration + GOC:mah + + + + + inhibition of mononuclear cell migration + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that increases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body. + mah + 2010-02-16T02:15:29Z + up regulation of mononuclear cell migration + up-regulation of mononuclear cell migration + upregulation of mononuclear cell migration + activation of mononuclear cell migration + stimulation of mononuclear cell migration + biological_process + GO:0071677 + positive regulation of mononuclear cell migration + + + + + Any process that increases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body. + GOC:mah + + + + + up regulation of mononuclear cell migration + GOC:mah + + + + + up-regulation of mononuclear cell migration + GOC:mah + + + + + upregulation of mononuclear cell migration + GOC:mah + + + + + activation of mononuclear cell migration + GOC:mah + + + + + stimulation of mononuclear cell migration + GOC:mah + + + + + + + + + The developmental process in which an organism emerges from a surrounding protective structure such as an egg or pupa case. + mah + 2010-02-19T04:23:55Z + biological_process + GO:0071684 + organism emergence from protective structure + + + + + The developmental process in which an organism emerges from a surrounding protective structure such as an egg or pupa case. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process in which a protein is transported from one specific location in the extracellular region to another, or maintained in a specific extracellular location. + mah + 2010-02-25T04:00:13Z + protein localisation in extracellular region + protein localization in extracellular region + biological_process + GO:0071692 + protein localization to extracellular region + + + + + Any process in which a protein is transported from one specific location in the extracellular region to another, or maintained in a specific extracellular location. + GOC:mah + + + + + protein localisation in extracellular region + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure to attain its fully functional state. + mah + 2010-03-02T11:43:38Z + biological_process + GO:0071695 + anatomical structure maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure to attain its fully functional state. + GOC:mah + + + + + + + + + + + + + + + + + + + + + The progression of an ectodermal placode over time from its initial formation until its mature state. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm. + mah + 2010-03-02T11:48:01Z + biological_process + GO:0071696 + ectodermal placode development + + + + + The progression of an ectodermal placode over time from its initial formation until its mature state. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of an ectodermal placode are generated and organized. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm. + mah + 2010-03-02T11:49:51Z + biological_process + GO:0071697 + ectodermal placode morphogenesis + + + + + The process in which the anatomical structures of an ectodermal placode are generated and organized. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm. + GOC:mah + + + + + + + + + + + + + + + + + + + + The progression of the olfactory placode over time from its initial formation until its mature state. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity. + mah + 2010-03-02T12:45:14Z + biological_process + GO:0071698 + olfactory placode development + + + + + The progression of the olfactory placode over time from its initial formation until its mature state. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the olfactory placode are generated and organized. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity. + mah + 2010-03-02T12:45:45Z + biological_process + GO:0071699 + olfactory placode morphogenesis + + + + + The process in which the anatomical structures of the olfactory placode are generated and organized. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the olfactory placode to attain its fully functional state. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity. + mah + 2010-03-02T01:10:54Z + biological_process + GO:0071700 + olfactory placode maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the olfactory placode to attain its fully functional state. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity. + GOC:mah + + + + + + + + + + + + + + + + + + + The directed movement of organic substances into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore. An organic substance is a molecular entity that contains carbon. + mah + 2010-03-08T02:15:14Z + biological_process + GO:0071702 + organic substance transport + + + + + The directed movement of organic substances into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore. An organic substance is a molecular entity that contains carbon. + GOC:mah + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon. + mah + 2010-03-08T03:32:18Z + organic molecular entity metabolic process + organic molecular entity metabolism + organic substance metabolism + biological_process + GO:0071704 + organic substance metabolic process + + + + + The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon. + GOC:mah + + + + + + + + + + + + + + + + + + + + The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + mah + 2010-03-08T03:56:28Z + biological_process + GO:0071705 + nitrogen compound transport + + + + + The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + The aggregation, arrangement and bonding together of a set of components to form a membrane. + mah + 2010-03-10T11:19:17Z + biological_process + GO:0071709 + membrane assembly + + + + + The aggregation, arrangement and bonding together of a set of components to form a membrane. + GOC:mah + + + + + + + + + + + + + + + + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the basement membrane. + mah + 2010-03-10T11:57:10Z + basement membrane organisation + biological_process + GO:0071711 + Note that this term has no relationship to 'membrane organization ; GO:0061024' because the basement membrane is not a lipid bilayer. + basement membrane organization + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the basement membrane. + GOC:mah + + + + + basement membrane organisation + GOC:mah + + + + + + + + + + + + + + + + + + + + + The progression of the beak over time from its initial formation until its mature state. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus. + mah + 2010-03-17T03:52:48Z + biological_process + GO:0071728 + beak development + + + + + The progression of the beak over time from its initial formation until its mature state. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus. + GOC:lp + ISBN:0702008729 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the beak are generated and organized. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus. + mah + 2010-03-17T03:54:34Z + biological_process + GO:0071729 + beak morphogenesis + + + + + The process in which the anatomical structures of the beak are generated and organized. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus. + GOC:lp + ISBN:0702008729 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to the beak. This process pertains to the initial formation of a structure from unspecified parts. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus. + mah + 2010-03-17T03:57:07Z + biological_process + GO:0071730 + beak formation + + + + + The process that gives rise to the beak. This process pertains to the initial formation of a structure from unspecified parts. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus. + GOC:lp + ISBN:0702008729 + + + + + + + + + + + + + + + + + + + + + + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner or outer membrane. + mah + 2010-03-29T03:59:35Z + nuclear membrane organisation + biological_process + nuclear membrane organization and biogenesis + GO:0071763 + nuclear membrane organization + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner or outer membrane. + GOC:mah + + + + + nuclear membrane organisation + GOC:mah + + + + + nuclear membrane organization and biogenesis + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear outer membrane. + mah + 2010-03-29T04:03:37Z + nuclear outer membrane organisation + biological_process + nuclear outer membrane organization and biogenesis + GO:0071764 + nuclear outer membrane organization + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear outer membrane. + GOC:mah + + + + + nuclear outer membrane organisation + GOC:mah + + + + + nuclear outer membrane organization and biogenesis + GOC:mah + + + + + + + + + The regulated release of a mating pheromone, a peptide hormone that induces a behavioral or physiological response(s) from a responding organism or cell, that contributes to a process of sexual reproduction. + mah + 2010-09-09T11:22:35Z + mating-type pheromone secretion + biological_process + GO:0071834 + mating pheromone secretion + + + + + The regulated release of a mating pheromone, a peptide hormone that induces a behavioral or physiological response(s) from a responding organism or cell, that contributes to a process of sexual reproduction. + GOC:mah + + + + + mating-type pheromone secretion + GOC:vw + + + + + + + + + A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component. + mah + 2010-09-10T01:39:16Z + GO:0071841 + cellular component organisation or biogenesis + cellular component organisation or biogenesis at cellular level + cellular component organization or biogenesis at cellular level + biological_process + GO:0071840 + + + cellular component organization or biogenesis + + + + + A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component. + GOC:mah + + + + + cellular component organisation or biogenesis + GOC:mah + + + + + cellular component organisation or biogenesis at cellular level + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution. + mah + 2010-09-13T02:51:13Z + response to catecholamine stimulus + biological_process + GO:0071869 + response to catecholamine + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution. + GOC:BHF + GOC:mah + + + + + response to catecholamine stimulus + GOC:dos + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution. + mah + 2010-09-13T02:54:50Z + biological_process + GO:0071870 + cellular response to catecholamine stimulus + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution. + GOC:BHF + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system. + mah + 2010-09-13T03:31:53Z + response to noradrenaline stimulus + response to norepinephrine stimulus + biological_process + GO:0071873 + Note that epinephrine and norepinephrine are ligands for the same receptors, and there are multiple adrenergic receptors. + response to norepinephrine + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system. + GOC:BHF + GOC:mah + + + + + response to noradrenaline stimulus + GOC:mah + + + + + response to norepinephrine stimulus + GOC:dos + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system. + mah + 2010-09-13T03:33:32Z + cellular response to noradrenaline stimulus + biological_process + GO:0071874 + Note that epinephrine and norepinephrine are ligands for the same receptors, and there are multiple adrenergic receptors. + cellular response to norepinephrine stimulus + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system. + GOC:BHF + GOC:mah + + + + + cellular response to noradrenaline stimulus + GOC:mah + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell of neural crest origin acquires the specialized features of an odontoblast, a cell on the outer surface of the dental pulp whose biological function is the creation of dentin. + mah + 2010-09-14T04:00:40Z + biological_process + GO:0071895 + odontoblast differentiation + + + + + The process in which a relatively unspecialized cell of neural crest origin acquires the specialized features of an odontoblast, a cell on the outer surface of the dental pulp whose biological function is the creation of dentin. + GOC:sl + PMID:20425127 + + + + + + + + + The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures. + mah + 2010-10-04T01:51:47Z + cellular_component + GO:0071944 + + cell periphery + + + + + The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures. + GOC:mah + + + + + + + + + + + + + + + An supramolecular fiber that consists of an insoluble core of polymerized tropoelastin monomers and a surrounding mantle of microfibrils. Elastic fibers provide elasticity and recoiling to tissues and organs, and maintain structural integrity against mechanical strain. + mah + 2010-10-11T11:44:57Z + elastic fibre + elastin fiber + cellular_component + GO:0071953 + elastic fiber + + + + + An supramolecular fiber that consists of an insoluble core of polymerized tropoelastin monomers and a surrounding mantle of microfibrils. Elastic fibers provide elasticity and recoiling to tissues and organs, and maintain structural integrity against mechanical strain. + GOC:BHF + GOC:mah + PMID:20236620 + + + + + elastic fibre + GOC:mah + + + + + elastin fiber + GOC:BHF + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the renal system over time, from its formation to the mature structure. The renal system maintains fluid balance and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels. + mah + 2010-01-25T10:31:00Z + urinary system development + urinary tract development + biological_process + GO:0072001 + + renal system development + + + + + The process whose specific outcome is the progression of the renal system over time, from its formation to the mature structure. The renal system maintains fluid balance and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels. + GOC:mtg_kidney_jan10 + GOC:yaf + http://en.wikibooks.org/wiki/Human_Physiology/The_Urinary_System + + + + + urinary system development + GOC:yaf + + + + + urinary tract development + GOC:yaf + PMID:17881463 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the Malpighian tubule over time, from its formation to the mature structure. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which leads into the posterior part of the gut. + mah + 2010-01-25T10:54:30Z + biological_process + GO:0072002 + Malpighian tubule development + + + + + The process whose specific outcome is the progression of the Malpighian tubule over time, from its formation to the mature structure. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which leads into the posterior part of the gut. + FBbt:00005786 + GOC:mtg_kidney_jan10 + PMID:19783135 + + + + + + + + + + + + + + + + + + + + + + + + + + + The developmental process pertaining to the initial formation of a kidney rudiment from unspecified parts. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. + mah + 2010-01-25T11:18:58Z + biological_process + kidney anlage formation + GO:0072003 + kidney rudiment formation + + + + + The developmental process pertaining to the initial formation of a kidney rudiment from unspecified parts. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. + GOC:mtg_kidney_jan10 + + + + + kidney anlage formation + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the nephron over time, from its formation to the mature structure. A nephron is the functional unit of the kidney. + mah + 2010-01-25T01:37:16Z + biological_process + nephrogenesis + GO:0072006 + nephron development + + + + + The process whose specific outcome is the progression of the nephron over time, from its formation to the mature structure. A nephron is the functional unit of the kidney. + GOC:mtg_kidney_jan10 + + + + + nephrogenesis + GOC:rph + + + + + + + + + + + + + + + + + + + + The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the kidney as it progresses from its formation to the mature state. + mah + 2010-01-25T01:59:09Z + biological_process + GO:0072007 + mesangial cell differentiation + + + + + The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the kidney as it progresses from its formation to the mature state. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The nephron epithelium is a tissue that covers the surface of a nephron. + mah + 2010-01-25T02:01:39Z + biological_process + GO:0072009 + nephron epithelium development + + + + + The process whose specific outcome is the progression of the nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The nephron epithelium is a tissue that covers the surface of a nephron. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the glomerular epithelium over time, from its formation to the mature structure. The glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus. The glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros. + mah + 2010-01-25T02:02:14Z + biological_process + GO:0072010 + glomerular epithelium development + + + + + The process whose specific outcome is the progression of the glomerular epithelium over time, from its formation to the mature structure. The glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus. The glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the glomerular endothelium over time, from its formation to the mature structure. The glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus. + mah + 2010-01-25T02:02:57Z + biological_process + GO:0072011 + glomerular endothelium development + + + + + The process whose specific outcome is the progression of the glomerular endothelium over time, from its formation to the mature structure. The glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The biological process whose specific outcome is the progression of a glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the glomerulus vasculature and ends with the mature structure. The glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the glomerulus. + mah + 2010-01-25T02:05:04Z + biological_process + glomerulus capillary development + GO:0072012 + glomerulus vasculature development + + + + + The biological process whose specific outcome is the progression of a glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the glomerulus vasculature and ends with the mature structure. The glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the glomerulus. + GOC:mtg_kidney_jan10 + + + + + glomerulus capillary development + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the proximal tubule over time, from its formation to the mature structure. In mammals, the proximal tubule is a nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle. It has a brush border epithelial morphology. + mah + 2010-01-25T02:33:46Z + biological_process + GO:0072014 + proximal tubule development + + + + + The process whose specific outcome is the progression of the proximal tubule over time, from its formation to the mature structure. In mammals, the proximal tubule is a nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle. It has a brush border epithelial morphology. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a glomerular visceral epithelial cell over time, from its formation to the mature structure. A glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells. + https://github.com/geneontology/go-ontology/issues/23000 + mah + 2010-01-25T02:12:45Z + glomerular visceral epithelial cell development + biological_process + GO:0072015 + podocyte development + + + + + The process whose specific outcome is the progression of a glomerular visceral epithelial cell over time, from its formation to the mature structure. A glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a glomerular parietal epithelial cell over time, from its formation to the mature structure. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. + mah + 2010-01-25T02:13:16Z + Bowman's capsule development + biological_process + GO:0072016 + glomerular parietal epithelial cell development + + + + + The process whose specific outcome is the progression of a glomerular parietal epithelial cell over time, from its formation to the mature structure. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. + GOC:mtg_kidney_jan10 + + + + + Bowman's capsule development + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the distal tubule over time, from its formation to the mature structure. In mammals, the distal tubule is a nephron tubule that begins at the macula densa and extends to the connecting tubule. + mah + 2010-01-25T02:34:19Z + biological_process + GO:0072017 + distal tubule development + + + + + The process whose specific outcome is the progression of the distal tubule over time, from its formation to the mature structure. In mammals, the distal tubule is a nephron tubule that begins at the macula densa and extends to the connecting tubule. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the proximal convoluted tubule over time, from its formation to the mature structure. The proximal convoluted tubule is the most proximal portion of the proximal tubule and extends from the glomerular capsule to the proximal straight tubule. + mah + 2010-01-25T02:35:35Z + biological_process + GO:0072019 + proximal convoluted tubule development + + + + + The process whose specific outcome is the progression of the proximal convoluted tubule over time, from its formation to the mature structure. The proximal convoluted tubule is the most proximal portion of the proximal tubule and extends from the glomerular capsule to the proximal straight tubule. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the proximal straight tubule over time, from its formation to the mature structure. The proximal straight tubule is the part of the descending limb that extends from the proximal convoluted tubule to the descending thin tubule. + mah + 2010-01-25T02:36:14Z + S3 development + biological_process + GO:0072020 + proximal straight tubule development + + + + + The process whose specific outcome is the progression of the proximal straight tubule over time, from its formation to the mature structure. The proximal straight tubule is the part of the descending limb that extends from the proximal convoluted tubule to the descending thin tubule. + GOC:mtg_kidney_jan10 + + + + + S3 development + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of an ascending thin limb over time, from its formation to the mature structure. The ascending thin limb is a segment of a nephron tubule lying in the inner medulla that is permeable to ions but not to water and has a simple epithelium; active transepithelial solute transport is absent. + mah + 2010-01-25T02:37:13Z + biological_process + GO:0072021 + ascending thin limb development + + + + + The process whose specific outcome is the progression of an ascending thin limb over time, from its formation to the mature structure. The ascending thin limb is a segment of a nephron tubule lying in the inner medulla that is permeable to ions but not to water and has a simple epithelium; active transepithelial solute transport is absent. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the descending thin limb over time, from its formation to the mature structure. The descending thin limb is a part of the loop of Henle situated just after the proximal straight tubule (S3). It extends to the tip of the loop of Henle. + mah + 2010-01-25T02:37:47Z + biological_process + GO:0072022 + descending thin limb development + + + + + The process whose specific outcome is the progression of the descending thin limb over time, from its formation to the mature structure. The descending thin limb is a part of the loop of Henle situated just after the proximal straight tubule (S3). It extends to the tip of the loop of Henle. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the thick ascending limb over time, from its formation to the mature structure. The thick ascending limb is the last part of the loop of Henle. Its thick, mitochondria-rich epithelium characterizes the outer medulla, and is responsible for very avid active salt transport. At the macula densa, the thick ascending limb connects to the distal convoluted tubule. + mah + 2010-01-25T02:39:51Z + GO:0072026 + TAL development + biological_process + GO:0072023 + thick ascending limb development + + + + + The process whose specific outcome is the progression of the thick ascending limb over time, from its formation to the mature structure. The thick ascending limb is the last part of the loop of Henle. Its thick, mitochondria-rich epithelium characterizes the outer medulla, and is responsible for very avid active salt transport. At the macula densa, the thick ascending limb connects to the distal convoluted tubule. + GOC:mtg_kidney_jan10 + + + + + TAL development + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the macula densa over time, from its formation to the mature structure. The macula densa is an area of specialized cells in the distal tubule that makes contact with the vascular pole of the glomerulus. + mah + 2010-01-25T02:40:15Z + biological_process + GO:0072024 + macula densa development + + + + + The process whose specific outcome is the progression of the macula densa over time, from its formation to the mature structure. The macula densa is an area of specialized cells in the distal tubule that makes contact with the vascular pole of the glomerulus. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the distal convoluted tubule over time, from its formation to the mature structure. The distal convoluted tubule is the first segment of the nephron lying just downstream from the loop of Henle, immediately after the macula densa. Among other functions, in humans it is responsible for the reabsorption of about 5% of filtered sodium via the thiazide-sensitive Na-Cl symporter. + mah + 2010-01-25T02:40:45Z + biological_process + GO:0072025 + distal convoluted tubule development + + + + + The process whose specific outcome is the progression of the distal convoluted tubule over time, from its formation to the mature structure. The distal convoluted tubule is the first segment of the nephron lying just downstream from the loop of Henle, immediately after the macula densa. Among other functions, in humans it is responsible for the reabsorption of about 5% of filtered sodium via the thiazide-sensitive Na-Cl symporter. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the connecting tubule over time, from its formation to the mature structure. The connecting tubule is a tubular segment of the nephron; it connects the distal convoluted tubule to the collecting duct. + mah + 2010-01-25T02:42:05Z + connecting duct development + biological_process + GO:0072027 + connecting tubule development + + + + + The process whose specific outcome is the progression of the connecting tubule over time, from its formation to the mature structure. The connecting tubule is a tubular segment of the nephron; it connects the distal convoluted tubule to the collecting duct. + GOC:mtg_kidney_jan10 + + + + + connecting duct development + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the nephron are generated and organized. A nephron is the functional unit of the kidney. + mah + 2010-01-25T02:45:52Z + biological_process + GO:0072028 + nephron morphogenesis + + + + + The process in which the anatomical structures of the nephron are generated and organized. A nephron is the functional unit of the kidney. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a long nephron over time, from its formation to the mature structure. Long nephrons are associated with juxtamedullary glomeruli and extend into the inner medulla. + mah + 2010-01-25T02:49:08Z + biological_process + juxtamedullary nephron development + GO:0072029 + long nephron development + + + + + The process whose specific outcome is the progression of a long nephron over time, from its formation to the mature structure. Long nephrons are associated with juxtamedullary glomeruli and extend into the inner medulla. + GOC:mtg_kidney_jan10 + + + + + juxtamedullary nephron development + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a short nephron over time, from its formation to the mature structure. Short nephrons are associated with mid-cortical and superficial glomeruli, are situated entirely in the outer medulla, and have no thin ascending limb. + mah + 2010-01-25T02:49:32Z + biological_process + GO:0072030 + short nephron development + + + + + The process whose specific outcome is the progression of a short nephron over time, from its formation to the mature structure. Short nephrons are associated with mid-cortical and superficial glomeruli, are situated entirely in the outer medulla, and have no thin ascending limb. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the S1 portion of the proximal convoluted tubule over time, from its formation to the mature structure. The S1 portion is the initial portion of the proximal convoluted tubule and is responsible for avid reabsorption of water and solutes. + mah + 2010-01-25T02:55:57Z + S1 development + biological_process + GO:0072031 + proximal convoluted tubule segment 1 development + + + + + The process whose specific outcome is the progression of the S1 portion of the proximal convoluted tubule over time, from its formation to the mature structure. The S1 portion is the initial portion of the proximal convoluted tubule and is responsible for avid reabsorption of water and solutes. + GOC:mtg_kidney_jan10 + MA:0002612 + + + + + S1 development + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the S2 portion of the proximal convoluted tubule over time, from its formation to the mature structure. The S2 portion of the tubule is involved in reabsorption of water and sodium chloride. + mah + 2010-01-25T02:56:36Z + S2 development + biological_process + GO:0072032 + proximal convoluted tubule segment 2 development + + + + + The process whose specific outcome is the progression of the S2 portion of the proximal convoluted tubule over time, from its formation to the mature structure. The S2 portion of the tubule is involved in reabsorption of water and sodium chloride. + GOC:mtg_kidney_jan10 + MA:0002613 + + + + + S2 development + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + The developmental process pertaining to the initial formation of the renal vesicle from condensed mesenchymal cells. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells. + mah + 2010-01-25T02:57:03Z + biological_process + nephron epithelium formation + GO:0072033 + renal vesicle formation + + + + + The developmental process pertaining to the initial formation of the renal vesicle from condensed mesenchymal cells. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells. + GOC:mtg_kidney_jan10 + + + + + nephron epithelium formation + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the renal vesicle. + mah + 2010-01-25T03:04:24Z + biological_process + GO:0072036 + mesenchymal to epithelial transition involved in renal vesicle formation + + + + + A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the renal vesicle. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a collecting duct over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. It is the final common path through which urine flows before entering the ureter and then emptying into the bladder. + mah + 2010-01-25T03:18:06Z + biological_process + GO:0072044 + collecting duct development + + + + + The process whose specific outcome is the progression of a collecting duct over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. It is the final common path through which urine flows before entering the ureter and then emptying into the bladder. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate into the anatomical structures of the renal system. + mah + 2010-01-25T03:31:51Z + biological_process + renal system pattern formation + GO:0072048 + renal system pattern specification + + + + + Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate into the anatomical structures of the renal system. + GOC:mtg_kidney_jan10 + + + + + renal system pattern formation + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the comma-shaped body is generated and organized. The comma-shaped body is the precursor structure to the S-shaped body that contributes to the morphogenesis of the nephron. + mah + 2010-01-25T03:44:48Z + biological_process + GO:0072049 + comma-shaped body morphogenesis + + + + + The process in which the comma-shaped body is generated and organized. The comma-shaped body is the precursor structure to the S-shaped body that contributes to the morphogenesis of the nephron. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the S-shaped body is generated and organized. The S-shaped body is the successor of the comma-shaped body that contributes to the morphogenesis of the nephron. + mah + 2010-01-25T03:45:19Z + biological_process + GO:0072050 + S-shaped body morphogenesis + + + + + The process in which the S-shaped body is generated and organized. The S-shaped body is the successor of the comma-shaped body that contributes to the morphogenesis of the nephron. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the juxtaglomerular apparatus over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure that lies adjacent to the glomerulus and regulates kidney function. + mah + 2010-01-25T03:52:23Z + biological_process + GO:0072051 + juxtaglomerular apparatus development + + + + + The process whose specific outcome is the progression of the juxtaglomerular apparatus over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure that lies adjacent to the glomerulus and regulates kidney function. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the renal inner medulla over time, from its formation to the mature structure. The renal inner medulla is unique to mammalian kidneys and is the innermost region of the mammalian kidney. + mah + 2010-01-25T03:59:37Z + inner renal medulla development + biological_process + GO:0072053 + renal inner medulla development + + + + + The process whose specific outcome is the progression of the renal inner medulla over time, from its formation to the mature structure. The renal inner medulla is unique to mammalian kidneys and is the innermost region of the mammalian kidney. + GOC:mtg_kidney_jan10 + + + + + inner renal medulla development + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the renal outer medulla over time, from its formation to the mature structure. The renal outer medulla is the region of the kidney that lies between the renal cortex and the renal inner medulla. + mah + 2010-01-25T04:00:42Z + outer renal medulla development + biological_process + GO:0072054 + renal outer medulla development + + + + + The process whose specific outcome is the progression of the renal outer medulla over time, from its formation to the mature structure. The renal outer medulla is the region of the kidney that lies between the renal cortex and the renal inner medulla. + GOC:mtg_kidney_jan10 + + + + + outer renal medulla development + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the renal cortex over time, from its formation to the mature structure. The renal cortex is the outer region of the kidney. + mah + 2010-01-25T04:01:12Z + biological_process + GO:0072055 + renal cortex development + + + + + The process whose specific outcome is the progression of the renal cortex over time, from its formation to the mature structure. The renal cortex is the outer region of the kidney. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the kidney pyramids over time, from its formation to the mature structure. Kidney pyramids are the conical masses that constitute the renal medulla in a multi-lobed mammalian kidney; they contain the loops of Henle and the medullary collecting ducts. + mah + 2010-01-25T04:01:36Z + kidney pyramid development + pyramids development + renal medulla development + renal pyramid development + biological_process + GO:0072056 + pyramid development + + + + + The process whose specific outcome is the progression of the kidney pyramids over time, from its formation to the mature structure. Kidney pyramids are the conical masses that constitute the renal medulla in a multi-lobed mammalian kidney; they contain the loops of Henle and the medullary collecting ducts. + GOC:mtg_kidney_jan10 + + + + + kidney pyramid development + GOC:mah + + + + + pyramids development + GOC:mah + + + + + renal medulla development + GOC:mah + + + + + renal pyramid development + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the inner stripe over time, from its formation to the mature structure. The inner stripe is a deep, centrally located portion of the renal outer medulla and is traversed by thin descending and thick ascending portions of the loops of Henle. + mah + 2010-01-25T04:01:58Z + biological_process + GO:0072057 + inner stripe development + + + + + The process whose specific outcome is the progression of the inner stripe over time, from its formation to the mature structure. The inner stripe is a deep, centrally located portion of the renal outer medulla and is traversed by thin descending and thick ascending portions of the loops of Henle. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the outer stripe over time, from its formation to the mature structure. The outer stripe is the region of the kidney outer medulla that lies just below the cortex. The proximal straight tubules (S3) characterize this region. + mah + 2010-01-25T04:02:56Z + biological_process + GO:0072058 + outer stripe development + + + + + The process whose specific outcome is the progression of the outer stripe over time, from its formation to the mature structure. The outer stripe is the region of the kidney outer medulla that lies just below the cortex. The proximal straight tubules (S3) characterize this region. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the cortical collecting duct over time, from its formation to the mature structure. The cortical collecting duct is the portion of the collecting duct that resides in the renal cortex. + mah + 2010-01-25T04:07:07Z + biological_process + GO:0072059 + cortical collecting duct development + + + + + The process whose specific outcome is the progression of the cortical collecting duct over time, from its formation to the mature structure. The cortical collecting duct is the portion of the collecting duct that resides in the renal cortex. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the outer medullary collecting duct over time, from its formation to the mature structure. The outer medullary collecting duct is the portion of the collecting duct that lies in the renal outer medulla. + mah + 2010-01-25T04:08:18Z + biological_process + GO:0072060 + outer medullary collecting duct development + + + + + The process whose specific outcome is the progression of the outer medullary collecting duct over time, from its formation to the mature structure. The outer medullary collecting duct is the portion of the collecting duct that lies in the renal outer medulla. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the inner medullary collecting duct over time, from its formation to the mature structure. The inner medullary collecting duct is the portion of the collecting duct that lies in the renal inner medulla. + mah + 2010-01-25T04:08:45Z + biological_process + GO:0072061 + inner medullary collecting duct development + + + + + The process whose specific outcome is the progression of the inner medullary collecting duct over time, from its formation to the mature structure. The inner medullary collecting duct is the portion of the collecting duct that lies in the renal inner medulla. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the short descending thin limb over time, from its formation to the mature structure. The short descending thin limb is the descending thin limb of a short nephron that has a squamous epithelial morphology. + mah + 2010-01-25T04:12:39Z + biological_process + GO:0072063 + short descending thin limb development + + + + + The process whose specific outcome is the progression of the short descending thin limb over time, from its formation to the mature structure. The short descending thin limb is the descending thin limb of a short nephron that has a squamous epithelial morphology. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the long descending thin limb over time, from its formation to the mature structure. The long descending thin limb is the descending thin limb of a long nephron that has a squamous epithelial morphology. The long descending limb starts in the inner stripe of the outer medulla and extends into the inner medulla. + mah + 2010-01-25T04:13:17Z + biological_process + GO:0072064 + long descending thin limb development + + + + + The process whose specific outcome is the progression of the long descending thin limb over time, from its formation to the mature structure. The long descending thin limb is the descending thin limb of a long nephron that has a squamous epithelial morphology. The long descending limb starts in the inner stripe of the outer medulla and extends into the inner medulla. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the long descending thin limb bend over time, from its formation to the mature structure. The long descending thin limb bend is a part of the descending thin limb of a long nephron that lies beyond the prebend segment. + mah + 2010-01-25T04:13:38Z + biological_process + GO:0072065 + long descending thin limb bend development + + + + + The process whose specific outcome is the progression of the long descending thin limb bend over time, from its formation to the mature structure. The long descending thin limb bend is a part of the descending thin limb of a long nephron that lies beyond the prebend segment. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the prebend segment over time, from its formation to the mature structure. The prebend segment is a part of the descending thin limb that lies before the bend and exhibits permeabilities characteristic of the ascending limb, especially negligible water permeability. + mah + 2010-01-25T04:14:02Z + biological_process + GO:0072066 + prebend segment development + + + + + The process whose specific outcome is the progression of the prebend segment over time, from its formation to the mature structure. The prebend segment is a part of the descending thin limb that lies before the bend and exhibits permeabilities characteristic of the ascending limb, especially negligible water permeability. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the early distal convoluted tubule over time, from its formation to the mature structure. The early distal convoluted tubule contains DCT cells and is vasopressin-insensitive. + mah + 2010-01-25T04:15:17Z + biological_process + GO:0072067 + early distal convoluted tubule development + + + + + The process whose specific outcome is the progression of the early distal convoluted tubule over time, from its formation to the mature structure. The early distal convoluted tubule contains DCT cells and is vasopressin-insensitive. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the late distal convoluted tubule over time, from its formation to the mature structure. The late distal convoluted tubule contains DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive. + mah + 2010-01-25T04:15:50Z + biological_process + GO:0072068 + late distal convoluted tubule development + + + + + The process whose specific outcome is the progression of the late distal convoluted tubule over time, from its formation to the mature structure. The late distal convoluted tubule contains DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the loop of Henle over time, from its formation to the mature structure. The loop of Henle is a nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule. + mah + 2010-01-25T04:20:27Z + GO:0072018 + intermediate tubule development + biological_process + GO:0072070 + loop of Henle development + + + + + The process whose specific outcome is the progression of the loop of Henle over time, from its formation to the mature structure. The loop of Henle is a nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblast of the kidney as it progresses from its formation to the mature state. + mah + 2010-01-25T04:34:31Z + kidney interstitial cell differentiation + biological_process + GO:0072071 + kidney interstitial fibroblast differentiation + + + + + The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblast of the kidney as it progresses from its formation to the mature state. + GOC:mtg_kidney_jan10 + + + + + kidney interstitial cell differentiation + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of an epithelium in the kidney over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. + mah + 2010-01-25T04:37:42Z + biological_process + GO:0072073 + kidney epithelium development + + + + + The process whose specific outcome is the progression of an epithelium in the kidney over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The biological process whose specific outcome is the progression of a kidney mesenchyme from an initial condition to its mature state. This process begins with the formation of kidney mesenchyme and ends with the mature structure. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney. + mah + 2010-01-25T04:39:04Z + biological_process + GO:0072074 + kidney mesenchyme development + + + + + The biological process whose specific outcome is the progression of a kidney mesenchyme from an initial condition to its mature state. This process begins with the formation of kidney mesenchyme and ends with the mature structure. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The biological process whose specific outcome is the progression of a metanephric mesenchyme from an initial condition to its mature state. This process begins with the formation of metanephric mesenchyme and ends with the mature structure. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros. + mah + 2010-01-25T04:40:11Z + biological_process + GO:0072075 + metanephric mesenchyme development + + + + + The biological process whose specific outcome is the progression of a metanephric mesenchyme from an initial condition to its mature state. This process begins with the formation of metanephric mesenchyme and ends with the mature structure. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The biological process whose specific outcome is the progression of a nephrogenic mesenchyme from an initial condition to its mature state. This process begins with the formation of nephrogenic mesenchyme and ends with the mature structure. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron. + mah + 2010-01-25T04:40:44Z + biological_process + GO:0072076 + nephrogenic mesenchyme development + + + + + The biological process whose specific outcome is the progression of a nephrogenic mesenchyme from an initial condition to its mature state. This process begins with the formation of nephrogenic mesenchyme and ends with the mature structure. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the renal vesicle are generated and organized. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells. + mah + 2010-02-01T02:21:06Z + biological_process + GO:0072077 + renal vesicle morphogenesis + + + + + The process in which the anatomical structures of the renal vesicle are generated and organized. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of a nephron tubule are generated and organized. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney. + mah + 2010-02-01T02:25:14Z + biological_process + GO:0072078 + nephron tubule morphogenesis + + + + + The process in which the anatomical structures of a nephron tubule are generated and organized. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The developmental process pertaining to the initial formation of a nephron tubule from unspecified parts. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney. + mah + 2010-02-01T02:29:26Z + biological_process + GO:0072079 + nephron tubule formation + + + + + The developmental process pertaining to the initial formation of a nephron tubule from unspecified parts. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + The progression of a nephron tubule over time, from its initial formation to the mature structure. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney. + mah + 2010-02-01T02:32:12Z + biological_process + GO:0072080 + nephron tubule development + + + + + The progression of a nephron tubule over time, from its initial formation to the mature structure. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the renal vesicle over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells. + mah + 2010-02-08T01:18:31Z + biological_process + GO:0072087 + renal vesicle development + + + + + The process whose specific outcome is the progression of the renal vesicle over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the nephron epithelium are generated and organized. The nephron epithelium is a tissue that covers the surface of a nephron. + mah + 2010-02-08T01:19:06Z + biological_process + GO:0072088 + nephron epithelium morphogenesis + + + + + The process in which the anatomical structures of the nephron epithelium are generated and organized. The nephron epithelium is a tissue that covers the surface of a nephron. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The multiplication or reproduction of stem cells, resulting in the expansion of a stem cell population. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. + mah + 2010-02-08T02:03:36Z + biological_process + GO:0072089 + stem cell proliferation + + + + + The multiplication or reproduction of stem cells, resulting in the expansion of a stem cell population. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of stem cell proliferation. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. + mah + 2010-02-08T02:09:03Z + biological_process + GO:0072091 + regulation of stem cell proliferation + + + + + Any process that modulates the frequency, rate or extent of stem cell proliferation. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The developmental process pertaining to the initial formation of the metanephros. + mah + 2010-02-10T01:17:11Z + metanephros formation + biological_process + GO:0072093 + metanephric renal vesicle formation + + + + + The developmental process pertaining to the initial formation of the metanephros. + GOC:mtg_kidney_jan10 + + + + + metanephros formation + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + The developmental process that results in the creation of defined areas or spaces within the kidney along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate. + mah + 2010-02-10T02:06:24Z + kidney anterior/posterior pattern specification + biological_process + anterior/posterior pattern formation involved in kidney development + kidney anterior/posterior pattern formation + GO:0072098 + anterior/posterior pattern specification involved in kidney development + + + + + The developmental process that results in the creation of defined areas or spaces within the kidney along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate. + GOC:mtg_kidney_jan10 + + + + + kidney anterior/posterior pattern specification + GOC:mtg_kidney_jan10 + + + + + anterior/posterior pattern formation involved in kidney development + GOC:mtg_kidney_jan10 + + + + + kidney anterior/posterior pattern formation + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + The developmental process that results in the creation of defined areas or spaces within the ureteric bud along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate. + mah + 2010-02-10T02:12:09Z + biological_process + ureteric bud anterior/posterior pattern formation + GO:0072099 + anterior/posterior pattern specification involved in ureteric bud development + + + + + The developmental process that results in the creation of defined areas or spaces within the ureteric bud along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate. + GOC:mtg_kidney_jan10 + + + + + ureteric bud anterior/posterior pattern formation + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the glomerulus are generated and organized. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney. + mah + 2010-02-10T02:32:09Z + biological_process + GO:0072102 + glomerulus morphogenesis + + + + + The process in which the anatomical structures of the glomerulus are generated and organized. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the glomerulus vasculature are generated and organized. The glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the glomerulus. + mah + 2010-02-10T02:34:54Z + biological_process + GO:0072103 + glomerulus vasculature morphogenesis + + + + + The process in which the anatomical structures of the glomerulus vasculature are generated and organized. The glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the glomerulus. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to a glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts. + mah + 2010-02-10T02:40:40Z + biological_process + GO:0072104 + glomerular capillary formation + + + + + The process that gives rise to a glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + A wavelike sequence of involuntary muscular contraction and relaxation that passes along the ureter, impelling the contents onwards. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder. + mah + 2010-02-10T03:07:54Z + biological_process + GO:0072105 + ureteric peristalsis + + + + + A wavelike sequence of involuntary muscular contraction and relaxation that passes along the ureter, impelling the contents onwards. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct. + mah + 2010-02-12T02:34:40Z + biological_process + GO:0072106 + regulation of ureteric bud formation + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + Any process that increases the rate or extent of the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct. + mah + 2010-02-12T02:37:28Z + biological_process + GO:0072107 + positive regulation of ureteric bud formation + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that increases the rate or extent of the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + Any process that increases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros. + mah + 2010-02-12T02:45:57Z + biological_process + GO:0072108 + positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that increases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the glomerular mesangium over time, from its formation to the mature structure. The glomerular mesangium is the thin membrane connective tissue composed of mesangial cells, which helps to support the capillary loops in a renal glomerulus. + mah + 2010-02-22T10:35:24Z + biological_process + GO:0072109 + glomerular mesangium development + + + + + The process whose specific outcome is the progression of the glomerular mesangium over time, from its formation to the mature structure. The glomerular mesangium is the thin membrane connective tissue composed of mesangial cells, which helps to support the capillary loops in a renal glomerulus. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + The multiplication or reproduction of cells, resulting in the expansion of the population in the kidney. + mah + 2010-02-22T10:48:45Z + biological_process + GO:0072111 + cell proliferation involved in kidney development + + + + + The multiplication or reproduction of cells, resulting in the expansion of the population in the kidney. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of a glomerular visceral epithelial cell. A glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells. + https://github.com/geneontology/go-ontology/issues/23000 + mah + 2010-02-22T10:52:11Z + glomerular visceral epithelial cell differentiation + biological_process + GO:0072112 + podocyte differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized features of a glomerular visceral epithelial cell. A glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the head kidney over time, from its formation to the mature structure. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney. It is analogous to the mammalian bone marrow and the primary site of definitive hematopoiesis. + mah + 2010-02-22T11:09:38Z + biological_process + GO:0072113 + head kidney development + + + + + The process whose specific outcome is the progression of the head kidney over time, from its formation to the mature structure. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney. It is analogous to the mammalian bone marrow and the primary site of definitive hematopoiesis. + GOC:mtg_kidney_jan10 + ZFA:0000669 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the pronephros are generated and organized. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life. + mah + 2010-02-22T11:12:15Z + pronephric kidney morphogenesis + biological_process + GO:0072114 + pronephros morphogenesis + + + + + The process in which the anatomical structures of the pronephros are generated and organized. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life. + GOC:mtg_kidney_jan10 + + + + + pronephric kidney morphogenesis + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the head kidney are generated and organized. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney. + mah + 2010-02-22T11:13:37Z + biological_process + GO:0072115 + head kidney morphogenesis + + + + + The process in which the anatomical structures of the head kidney are generated and organized. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney. + GOC:mtg_kidney_jan10 + ZFA:0000669 + + + + + + + + + + + + + + + + + + + + + + + + + + The developmental process pertaining to the initial formation of the pronephros. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life. + mah + 2010-02-22T11:16:26Z + pronephric kidney formation + biological_process + GO:0072116 + pronephros formation + + + + + The developmental process pertaining to the initial formation of the pronephros. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life. + GOC:mtg_kidney_jan10 + + + + + pronephric kidney formation + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The developmental process pertaining to the initial formation of the head kidney. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney. + mah + 2010-02-22T11:17:20Z + biological_process + GO:0072117 + head kidney formation + + + + + The developmental process pertaining to the initial formation of the head kidney. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney. + GOC:mtg_kidney_jan10 + ZFA:0000669 + + + + + + + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the pronephros to attain its fully functional state. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life. + mah + 2010-02-22T11:25:48Z + pronephric kidney maturation + biological_process + GO:0072120 + pronephros maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the pronephros to attain its fully functional state. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life. + GOC:mtg_kidney_jan10 + + + + + pronephric kidney maturation + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the head kidney to attain its fully functional state. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney. + mah + 2010-02-22T11:28:08Z + biological_process + GO:0072121 + head kidney maturation + + + + + A developmental process, independent of morphogenetic (shape) change, that is required for the head kidney to attain its fully functional state. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney. + GOC:mtg_kidney_jan10 + ZFA:0000669 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the renal capsule over time, from its formation to the mature structure. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands. + mah + 2010-02-22T02:02:55Z + biological_process + GO:0072127 + renal capsule development + + + + + The process whose specific outcome is the progression of the renal capsule over time, from its formation to the mature structure. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the renal capsule are generated and organized. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands. + mah + 2010-02-22T02:06:19Z + biological_process + GO:0072128 + renal capsule morphogenesis + + + + + The process in which the anatomical structures of the renal capsule are generated and organized. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + The developmental process pertaining to the initial formation of a renal capsule from unspecified parts. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands. + mah + 2010-02-22T02:08:14Z + biological_process + GO:0072129 + renal capsule formation + + + + + The developmental process pertaining to the initial formation of a renal capsule from unspecified parts. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of a kidney mesenchymal tissue are generated and organized. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney. + mah + 2010-02-22T02:16:43Z + biological_process + GO:0072131 + kidney mesenchyme morphogenesis + + + + + The process in which the anatomical structures of a kidney mesenchymal tissue are generated and organized. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of a mesenchymal tissue are generated and organized. A mesenchymal tissue is made up of loosely packed stellate cells. + mah + 2010-02-22T02:17:15Z + biological_process + GO:0072132 + mesenchyme morphogenesis + + + + + The process in which the anatomical structures of a mesenchymal tissue are generated and organized. A mesenchymal tissue is made up of loosely packed stellate cells. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of a metanephric mesenchymal tissue are generated and organized. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros. + mah + 2010-02-22T02:20:14Z + biological_process + GO:0072133 + metanephric mesenchyme morphogenesis + + + + + The process in which the anatomical structures of a metanephric mesenchymal tissue are generated and organized. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of a nephrogenic mesenchymal tissue are generated and organized. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron. + mah + 2010-02-22T02:21:16Z + biological_process + GO:0072134 + nephrogenic mesenchyme morphogenesis + + + + + The process in which the anatomical structures of a nephrogenic mesenchymal tissue are generated and organized. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureteric bud, that contributes to ureteric bud development. + mah + 2010-02-22T02:40:38Z + ureteric bud mesenchymal cell proliferation + biological_process + GO:0072138 + mesenchymal cell proliferation involved in ureteric bud development + + + + + The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureteric bud, that contributes to ureteric bud development. + GOC:mtg_kidney_jan10 + + + + + ureteric bud mesenchymal cell proliferation + GOC:mtg_kidney_jan10 + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of a glomerular parietal epithelial cell. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. + mah + 2010-02-24T01:33:05Z + biological_process + GO:0072139 + glomerular parietal epithelial cell differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized features of a glomerular parietal epithelial cell. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a renal interstitial fibroblast over time, from its formation to the mature structure. + mah + 2010-02-24T01:39:05Z + kidney interstitial cell development + biological_process + GO:0072141 + renal interstitial fibroblast development + + + + + The process whose specific outcome is the progression of a renal interstitial fibroblast over time, from its formation to the mature structure. + GOC:mtg_kidney_jan10 + + + + + kidney interstitial cell development + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a mesangial cell in the kidney over time, from its formation to the mature structure. + mah + 2010-02-24T01:44:28Z + biological_process + GO:0072143 + mesangial cell development + + + + + The process whose specific outcome is the progression of a mesangial cell in the kidney over time, from its formation to the mature structure. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + The orderly movement of epithelial cells within a renal tubule that contributes to nephron tubule morphogenesis. + mah + 2010-02-24T02:21:25Z + biological_process + GO:0072155 + epithelial cell migration involved in nephron tubule morphogenesis + + + + + The orderly movement of epithelial cells within a renal tubule that contributes to nephron tubule morphogenesis. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of a distal tubule are generated and organized. The distal tubule is a nephron tubule that begins at the macula densa and extends to the connecting tubule. + mah + 2010-02-24T02:32:03Z + biological_process + GO:0072156 + distal tubule morphogenesis + + + + + The process in which the anatomical structures of a distal tubule are generated and organized. The distal tubule is a nephron tubule that begins at the macula densa and extends to the connecting tubule. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + The orderly movement of epithelial cells within a renal tubule that contributes to distal tubule morphogenesis. + mah + 2010-02-24T02:33:33Z + biological_process + GO:0072157 + epithelial cell migration involved in distal tubule morphogenesis + + + + + The orderly movement of epithelial cells within a renal tubule that contributes to distal tubule morphogenesis. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of a proximal tubule are generated and organized. The proximal tubule is a nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle. It has a brush border epithelial morphology. + mah + 2010-02-24T02:35:36Z + biological_process + GO:0072158 + proximal tubule morphogenesis + + + + + The process in which the anatomical structures of a proximal tubule are generated and organized. The proximal tubule is a nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle. It has a brush border epithelial morphology. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + The orderly movement of epithelial cells within a renal tubule that contributes to proximal tubule morphogenesis. + mah + 2010-02-24T02:37:08Z + biological_process + GO:0072159 + epithelial cell migration involved in proximal tubule morphogenesis + + + + + The orderly movement of epithelial cells within a renal tubule that contributes to proximal tubule morphogenesis. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the kidney as it progresses from its formation to the mature state. + mah + 2010-02-26T01:31:49Z + biological_process + GO:0072161 + mesenchymal cell differentiation involved in kidney development + + + + + The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the kidney as it progresses from its formation to the mature state. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of an epithelium in the mesonephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. + mah + 2010-02-26T01:40:43Z + biological_process + GO:0072163 + mesonephric epithelium development + + + + + The process whose specific outcome is the progression of an epithelium in the mesonephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + The progression of a mesonephric tubule over time, from its initial formation to the mature structure. A mesonephric tubule is an epithelial tube that is part of the mesonephros. + mah + 2010-02-26T01:45:58Z + biological_process + GO:0072164 + mesonephric tubule development + + + + + The progression of a mesonephric tubule over time, from its initial formation to the mature structure. A mesonephric tubule is an epithelial tube that is part of the mesonephros. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + The progression of the anterior mesonephric tubule over time, from its initial formation to the mature structure. The anterior mesonephric tubule is an epithelial tube that is part of the mesonephros. + mah + 2010-02-26T01:47:26Z + biological_process + GO:0072165 + anterior mesonephric tubule development + + + + + The progression of the anterior mesonephric tubule over time, from its initial formation to the mature structure. The anterior mesonephric tubule is an epithelial tube that is part of the mesonephros. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + The progression of the posterior mesonephric tubule over time, from its initial formation to the mature structure. The posterior mesonephric tubule is an epithelial tube that is part of the mesonephros. + mah + 2010-02-26T01:47:50Z + biological_process + GO:0072166 + posterior mesonephric tubule development + + + + + The progression of the posterior mesonephric tubule over time, from its initial formation to the mature structure. The posterior mesonephric tubule is an epithelial tube that is part of the mesonephros. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of a metanephric tubule over time, from its initial formation to the mature structure. A metanephric tubule is an epithelial tube that is part of the metanephros. + mah + 2010-02-26T01:58:18Z + biological_process + GO:0072170 + metanephric tubule development + + + + + The progression of a metanephric tubule over time, from its initial formation to the mature structure. A metanephric tubule is an epithelial tube that is part of the metanephros. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of a mesonephric tubule are generated and organized. A mesonephric tubule is an epithelial tube that is part of the mesonephros. + mah + 2010-02-26T02:02:13Z + biological_process + GO:0072171 + mesonephric tubule morphogenesis + + + + + The process in which the anatomical structures of a mesonephric tubule are generated and organized. A mesonephric tubule is an epithelial tube that is part of the mesonephros. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The developmental process pertaining to the initial formation of a mesonephric tubule from unspecified parts. A mesonephric tubule is an epithelial tube that is part of the mesonephros. + mah + 2010-02-26T02:02:37Z + biological_process + GO:0072172 + mesonephric tubule formation + + + + + The developmental process pertaining to the initial formation of a mesonephric tubule from unspecified parts. A mesonephric tubule is an epithelial tube that is part of the mesonephros. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of a metanephric tubule are generated and organized from an epithelium. A metanephric tubule is an epithelial tube that is part of the metanephros. + mah + 2010-02-26T02:06:42Z + biological_process + GO:0072173 + metanephric tubule morphogenesis + + + + + The process in which the anatomical structures of a metanephric tubule are generated and organized from an epithelium. A metanephric tubule is an epithelial tube that is part of the metanephros. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The developmental process pertaining to the initial formation of a metanephric tubule. + mah + 2010-02-26T02:07:41Z + biological_process + GO:0072174 + metanephric tubule formation + + + + + The developmental process pertaining to the initial formation of a metanephric tubule. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The developmental process pertaining to the initial formation of an epithelial tube. + mah + 2010-02-26T02:15:40Z + biological_process + GO:0072175 + epithelial tube formation + + + + + The developmental process pertaining to the initial formation of an epithelial tube. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a nephric duct over time, from its initial formation to a mature structure. A nephric duct is a tube that drains a primitive kidney. + mah + 2010-02-26T02:27:31Z + biological_process + GO:0072176 + nephric duct development + + + + + The process whose specific outcome is the progression of a nephric duct over time, from its initial formation to a mature structure. A nephric duct is a tube that drains a primitive kidney. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a mesonephric duct over time, from its initial formation to a mature structure. A mesonephric duct is a tube drains the mesonephros. + mah + 2010-02-26T02:32:22Z + Wolffian duct development + biological_process + GO:0072177 + mesonephric duct development + + + + + The process whose specific outcome is the progression of a mesonephric duct over time, from its initial formation to a mature structure. A mesonephric duct is a tube drains the mesonephros. + GOC:mtg_kidney_jan10 + + + + + Wolffian duct development + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the nephric duct are generated and organized. A nephric duct is a tube that drains a primitive kidney. + mah + 2010-02-26T02:35:29Z + biological_process + GO:0072178 + nephric duct morphogenesis + + + + + The process in which the anatomical structures of the nephric duct are generated and organized. A nephric duct is a tube that drains a primitive kidney. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + The developmental process pertaining to the initial formation of a nephric duct. A nephric duct is a tube that drains a primitive kidney. + mah + 2010-02-26T02:35:55Z + biological_process + GO:0072179 + nephric duct formation + + + + + The developmental process pertaining to the initial formation of a nephric duct. A nephric duct is a tube that drains a primitive kidney. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the mesonephric duct are generated and organized. A mesonephric duct is a tube drains the mesonephros. + mah + 2010-02-26T02:37:13Z + biological_process + Wolffian duct morphogenesis + GO:0072180 + mesonephric duct morphogenesis + + + + + The process in which the anatomical structures of the mesonephric duct are generated and organized. A mesonephric duct is a tube drains the mesonephros. + GOC:mtg_kidney_jan10 + + + + + Wolffian duct morphogenesis + GOC:dph + + + + + + + + + + + + + + + + + + + + + + The developmental process pertaining to the initial formation of a mesonephric duct. A mesonephric duct is a tube that drains the mesonephros. + mah + 2010-02-26T02:38:03Z + Wolffian duct formation + biological_process + GO:0072181 + mesonephric duct formation + + + + + The developmental process pertaining to the initial formation of a mesonephric duct. A mesonephric duct is a tube that drains the mesonephros. + GOC:mtg_kidney_jan10 + + + + + Wolffian duct formation + GOC:dph + + + + + + + + + + + + + + + + + + + + The biological process whose specific outcome is the progression of the metanephric cap from an initial condition to its mature state. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip. + mah + 2010-03-01T01:20:22Z + biological_process + GO:0072185 + metanephric cap development + + + + + The biological process whose specific outcome is the progression of the metanephric cap from an initial condition to its mature state. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the metanephric cap are generated and organized. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip. + mah + 2010-03-01T01:22:51Z + biological_process + GO:0072186 + metanephric cap morphogenesis + + + + + The process in which the anatomical structures of the metanephric cap are generated and organized. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + The developmental process pertaining to the initial formation of a metanephric cap from unspecified parts. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip. + mah + 2010-03-01T01:26:53Z + biological_process + GO:0072187 + metanephric cap formation + + + + + The developmental process pertaining to the initial formation of a metanephric cap from unspecified parts. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the ureter over time, from its formation to the mature structure. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut. + mah + 2010-03-01T01:44:14Z + biological_process + GO:0072189 + ureter development + + + + + The process whose specific outcome is the progression of the ureter over time, from its formation to the mature structure. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the urothelium of the ureter over time, from its formation to the mature structure. The urothelium is an epithelium that makes up the epithelial tube of the ureter. + mah + 2010-03-01T01:46:31Z + ureter epithelium development + biological_process + GO:0072190 + ureter urothelium development + + + + + The process whose specific outcome is the progression of the urothelium of the ureter over time, from its formation to the mature structure. The urothelium is an epithelium that makes up the epithelial tube of the ureter. + GOC:mtg_kidney_jan10 + + + + + ureter epithelium development + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of smooth muscle in the ureter over time, from its formation to the mature structure. + mah + 2010-03-01T01:48:53Z + biological_process + GO:0072191 + ureter smooth muscle development + + + + + The process whose specific outcome is the progression of smooth muscle in the ureter over time, from its formation to the mature structure. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + The process whose specific outcome is the progression of smooth muscle in the kidney over time, from its formation to the mature structure. + mah + 2010-03-01T02:05:30Z + biological_process + GO:0072194 + kidney smooth muscle tissue development + + + + + The process whose specific outcome is the progression of smooth muscle in the kidney over time, from its formation to the mature structure. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the ureter are generated and organized. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder. + mah + 2010-03-01T02:24:55Z + biological_process + GO:0072197 + ureter morphogenesis + + + + + The process in which the anatomical structures of the ureter are generated and organized. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureter, that contributes to ureter development. + mah + 2010-03-01T03:24:41Z + biological_process + ureter mesenchymal cell proliferation + ureteral mesenchymal cell proliferation + GO:0072198 + mesenchymal cell proliferation involved in ureter development + + + + + The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureter, that contributes to ureter development. + GOC:mtg_kidney_jan10 + + + + + ureter mesenchymal cell proliferation + GOC:mtg_kidney_jan10 + + + + + ureteral mesenchymal cell proliferation + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the ureter gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. + mah + 2010-03-01T03:38:13Z + biological_process + regulation of ureter mesenchymal cell proliferation + regulation of ureteral mesenchymal cell proliferation + GO:0072199 + regulation of mesenchymal cell proliferation involved in ureter development + + + + + Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the ureter gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. + GOC:mtg_kidney_jan10 + + + + + regulation of ureter mesenchymal cell proliferation + GOC:mtg_kidney_jan10 + + + + + regulation of ureteral mesenchymal cell proliferation + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the ureter gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. + mah + 2010-03-01T03:42:31Z + biological_process + negative regulation of ureter mesenchymal cell proliferation + negative regulation of ureteral mesenchymal cell proliferation + GO:0072200 + negative regulation of mesenchymal cell proliferation involved in ureter development + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the ureter gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. + GOC:mtg_kidney_jan10 + + + + + negative regulation of ureter mesenchymal cell proliferation + GOC:mtg_kidney_jan10 + + + + + negative regulation of ureteral mesenchymal cell proliferation + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. + mah + 2010-03-01T03:43:29Z + biological_process + GO:0072201 + negative regulation of mesenchymal cell proliferation + + + + + Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephros as it progresses from its formation to the mature state. + mah + 2010-03-18T10:40:14Z + biological_process + GO:0072202 + cell differentiation involved in metanephros development + + + + + The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephros as it progresses from its formation to the mature state. + GOC:mah + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + The multiplication or reproduction of cells, resulting in the expansion of the population in the metanephros. + mah + 2010-03-18T10:42:27Z + biological_process + GO:0072203 + cell proliferation involved in metanephros development + + + + + The multiplication or reproduction of cells, resulting in the expansion of the population in the metanephros. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + Any process that mediates the transfer of information from one cell to another and contributes to the progression of the metanephros over time, from its formation to the mature organ. + mah + 2010-03-18T10:54:36Z + cell-cell signalling involved in metanephros development + biological_process + GO:0072204 + cell-cell signaling involved in metanephros development + + + + + Any process that mediates the transfer of information from one cell to another and contributes to the progression of the metanephros over time, from its formation to the mature organ. + GOC:mtg_kidney_jan10 + + + + + cell-cell signalling involved in metanephros development + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a collecting duct in the metanephros over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder. + mah + 2010-03-18T11:15:37Z + biological_process + GO:0072205 + metanephric collecting duct development + + + + + The process whose specific outcome is the progression of a collecting duct in the metanephros over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the juxtaglomerular apparatus in the metanephros over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate. + mah + 2010-03-18T11:17:47Z + biological_process + GO:0072206 + metanephric juxtaglomerular apparatus development + + + + + The process whose specific outcome is the progression of the juxtaglomerular apparatus in the metanephros over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of an epithelium in the metanephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. + mah + 2010-03-18T11:50:37Z + biological_process + GO:0072207 + metanephric epithelium development + + + + + The process whose specific outcome is the progression of an epithelium in the metanephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of smooth muscle in the metanephros over time, from its formation to the mature structure. + mah + 2010-03-18T11:51:59Z + biological_process + GO:0072208 + metanephric smooth muscle tissue development + + + + + The process whose specific outcome is the progression of smooth muscle in the metanephros over time, from its formation to the mature structure. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a nephron in the metanephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney. + mah + 2010-03-18T12:52:57Z + biological_process + GO:0072210 + metanephric nephron development + + + + + The process whose specific outcome is the progression of a nephron in the metanephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the metanephric pyramids over time, from their formation to the mature structures. Metanephric pyramids are the conical masses that constitute the renal medulla in a metanephros; they contain the loops of Henle and the medullary collecting ducts. + mah + 2010-03-18T01:04:51Z + metanephric kidney pyramid development + metanephric pyramid development + metanephric renal medulla development + metanephric renal pyramid development + biological_process + GO:0072211 + metanephric pyramids development + + + + + The process whose specific outcome is the progression of the metanephric pyramids over time, from their formation to the mature structures. Metanephric pyramids are the conical masses that constitute the renal medulla in a metanephros; they contain the loops of Henle and the medullary collecting ducts. + GOC:mtg_kidney_jan10 + + + + + metanephric kidney pyramid development + GOC:mah + + + + + metanephric pyramid development + GOC:mah + + + + + metanephric renal medulla development + GOC:mah + + + + + metanephric renal pyramid development + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the metanephric capsule over time, from its formation to the mature structure. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. + mah + 2010-03-18T01:25:19Z + biological_process + GO:0072213 + metanephric capsule development + + + + + The process whose specific outcome is the progression of the metanephric capsule over time, from its formation to the mature structure. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the metanephric cortex over time, from its formation to the mature structure. The metanephric cortex is the outer region of the metanephros. + mah + 2010-03-18T01:29:49Z + biological_process + GO:0072214 + metanephric cortex development + + + + + The process whose specific outcome is the progression of the metanephric cortex over time, from its formation to the mature structure. The metanephric cortex is the outer region of the metanephros. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + Any process that modulates the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine. + biological_process + GO:0072215 + regulation of metanephros development + + + + + Any process that modulates the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + Any process that increases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. + mah + 2010-03-18T01:40:12Z + biological_process + GO:0072216 + positive regulation of metanephros development + + + + + Any process that increases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + Any process that decreases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. + mah + 2010-03-18T01:45:48Z + biological_process + GO:0072217 + negative regulation of metanephros development + + + + + Any process that decreases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a metanephric ascending thin limb over time, from its formation to the mature structure. The metanephric ascending thin limb is a segment of a nephron tubule in the metanephros lying in the inner medulla that is permeable to ions but not to water and has a simple epithelium; active transepithelial solute transport is absent. + mah + 2010-03-18T03:34:42Z + biological_process + GO:0072218 + metanephric ascending thin limb development + + + + + The process whose specific outcome is the progression of a metanephric ascending thin limb over time, from its formation to the mature structure. The metanephric ascending thin limb is a segment of a nephron tubule in the metanephros lying in the inner medulla that is permeable to ions but not to water and has a simple epithelium; active transepithelial solute transport is absent. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the metanephric cortical collecting duct over time, from its formation to the mature structure. The metanephric cortical collecting duct is the portion of the metanephric collecting duct that resides in the renal cortex. + mah + 2010-03-18T03:34:52Z + biological_process + GO:0072219 + metanephric cortical collecting duct development + + + + + The process whose specific outcome is the progression of the metanephric cortical collecting duct over time, from its formation to the mature structure. The metanephric cortical collecting duct is the portion of the metanephric collecting duct that resides in the renal cortex. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the metanephric descending thin limb over time, from its formation to the mature structure. The metanephric descending thin limb is a part of the metanephric loop of Henle situated just after the proximal straight tubule (S3). It extends to the tip of the metanephric loop of Henle. + mah + 2010-03-18T03:35:05Z + biological_process + GO:0072220 + metanephric descending thin limb development + + + + + The process whose specific outcome is the progression of the metanephric descending thin limb over time, from its formation to the mature structure. The metanephric descending thin limb is a part of the metanephric loop of Henle situated just after the proximal straight tubule (S3). It extends to the tip of the metanephric loop of Henle. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the metanephric distal convoluted tubule over time, from its formation to the mature structure. The metanephric distal convoluted tubule is the first segment of the metanephric nephron lying just downstream from the loop of Henle, immediately after the macula densa. Among other functions, in humans it is responsible for the reabsorption of about 5% of filtered sodium via the thiazide-sensitive Na-Cl symporter. + mah + 2010-03-18T03:35:27Z + biological_process + GO:0072221 + metanephric distal convoluted tubule development + + + + + The process whose specific outcome is the progression of the metanephric distal convoluted tubule over time, from its formation to the mature structure. The metanephric distal convoluted tubule is the first segment of the metanephric nephron lying just downstream from the loop of Henle, immediately after the macula densa. Among other functions, in humans it is responsible for the reabsorption of about 5% of filtered sodium via the thiazide-sensitive Na-Cl symporter. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the metanephric early distal convoluted tubule over time, from its formation to the mature structure. The metanephric early distal convoluted tubule contains metanephric DCT cells and is vasopressin-insensitive. + mah + 2010-03-18T03:35:46Z + biological_process + GO:0072222 + metanephric early distal convoluted tubule development + + + + + The process whose specific outcome is the progression of the metanephric early distal convoluted tubule over time, from its formation to the mature structure. The metanephric early distal convoluted tubule contains metanephric DCT cells and is vasopressin-insensitive. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the metanephric glomerular mesangium over time, from its formation to the mature structure. The metanephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the metanephros, which helps to support the capillary loops in a renal glomerulus. + mah + 2010-03-18T03:35:56Z + biological_process + GO:0072223 + metanephric glomerular mesangium development + + + + + The process whose specific outcome is the progression of the metanephric glomerular mesangium over time, from its formation to the mature structure. The metanephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the metanephros, which helps to support the capillary loops in a renal glomerulus. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or metanephros. + mah + 2010-03-18T03:36:20Z + metanephric glomerular development + biological_process + GO:0072224 + metanephric glomerulus development + + + + + The progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or metanephros. + GOC:mah + + + + + metanephric glomerular development + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the metanephric late distal convoluted tubule over time, from its formation to the mature structure. The metanephric late distal convoluted tubule contains metanephric DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive. + mah + 2010-03-18T03:37:04Z + biological_process + GO:0072225 + metanephric late distal convoluted tubule development + + + + + The process whose specific outcome is the progression of the metanephric late distal convoluted tubule over time, from its formation to the mature structure. The metanephric late distal convoluted tubule contains metanephric DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the metanephric long descending thin limb bend over time, from its formation to the mature structure. The metanephric long descending thin limb bend is a part of the descending thin limb of a long nephron that lies beyond the prebend segment in the metanephros. + mah + 2010-03-18T03:37:16Z + biological_process + GO:0072226 + metanephric long descending thin limb bend development + + + + + The process whose specific outcome is the progression of the metanephric long descending thin limb bend over time, from its formation to the mature structure. The metanephric long descending thin limb bend is a part of the descending thin limb of a long nephron that lies beyond the prebend segment in the metanephros. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the metanephric macula densa over time, from its formation to the mature structure. The metanephric macula densa is an area of specialized cells in the distal tubule of the metanephros that makes contact with the vascular pole of the glomerulus. + mah + 2010-03-18T03:37:26Z + biological_process + GO:0072227 + metanephric macula densa development + + + + + The process whose specific outcome is the progression of the metanephric macula densa over time, from its formation to the mature structure. The metanephric macula densa is an area of specialized cells in the distal tubule of the metanephros that makes contact with the vascular pole of the glomerulus. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the metanephric prebend segment over time, from its formation to the mature structure. The metanephric prebend segment is a part of the metanephric descending thin limb that lies before the bend and exhibits permeabilities characteristic of the ascending limb, especially negligible water permeability. + mah + 2010-03-18T03:37:46Z + biological_process + GO:0072228 + metanephric prebend segment development + + + + + The process whose specific outcome is the progression of the metanephric prebend segment over time, from its formation to the mature structure. The metanephric prebend segment is a part of the metanephric descending thin limb that lies before the bend and exhibits permeabilities characteristic of the ascending limb, especially negligible water permeability. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The metanephric proximal convoluted tubule is the most proximal portion of the metanephric proximal tubule and extends from the metanephric glomerular capsule to the metanephric proximal straight tubule. + mah + 2010-03-18T03:37:56Z + biological_process + GO:0072229 + metanephric proximal convoluted tubule development + + + + + The process whose specific outcome is the progression of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The metanephric proximal convoluted tubule is the most proximal portion of the metanephric proximal tubule and extends from the metanephric glomerular capsule to the metanephric proximal straight tubule. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the metanephric proximal straight tubule over time, from its formation to the mature structure. The metanephric proximal straight tubule is the part of the metanephric descending limb that extends from the metanephric proximal convoluted tubule to the metanephric descending thin tubule. + mah + 2010-03-18T03:38:53Z + metanephric S3 development + biological_process + GO:0072230 + metanephric proximal straight tubule development + + + + + The process whose specific outcome is the progression of the metanephric proximal straight tubule over time, from its formation to the mature structure. The metanephric proximal straight tubule is the part of the metanephric descending limb that extends from the metanephric proximal convoluted tubule to the metanephric descending thin tubule. + GOC:mtg_kidney_jan10 + + + + + metanephric S3 development + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the S1 portion of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The S1 portion is the initial portion of the metanephric proximal convoluted tubule and is responsible for avid reabsorption of water and solutes. + mah + 2010-03-18T03:39:10Z + metanephric S1 development + biological_process + GO:0072231 + metanephric proximal convoluted tubule segment 1 development + + + + + The process whose specific outcome is the progression of the S1 portion of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The S1 portion is the initial portion of the metanephric proximal convoluted tubule and is responsible for avid reabsorption of water and solutes. + GOC:bf + GOC:mtg_kidney_jan10 + + + + + metanephric S1 development + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the metanephric thick ascending limb over time, from its formation to the mature structure. The metanephric thick ascending limb is the last part of the metanephric loop of Henle. Its thick, mitochondria-rich epithelium characterizes the outer medulla, and is responsible for very avid active salt transport. At the macula densa, the thick ascending limb connects to the distal convoluted tubule. + mah + 2010-03-18T03:39:36Z + metanephric TAL development + biological_process + GO:0072233 + metanephric thick ascending limb development + + + + + The process whose specific outcome is the progression of the metanephric thick ascending limb over time, from its formation to the mature structure. The metanephric thick ascending limb is the last part of the metanephric loop of Henle. Its thick, mitochondria-rich epithelium characterizes the outer medulla, and is responsible for very avid active salt transport. At the macula densa, the thick ascending limb connects to the distal convoluted tubule. + GOC:mtg_kidney_jan10 + + + + + metanephric TAL development + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + The progression of a metanephric nephron tubule over time, from its initial formation to the mature structure. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros. + mah + 2010-03-18T03:41:23Z + biological_process + GO:0072234 + metanephric nephron tubule development + + + + + The progression of a metanephric nephron tubule over time, from its initial formation to the mature structure. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the metanephric distal tubule over time, from its formation to the mature structure. The metanephric distal tubule is a metanephric nephron tubule that begins at the metanephric macula densa and extends to the metanephric connecting tubule. + mah + 2010-03-18T03:45:37Z + biological_process + GO:0072235 + metanephric distal tubule development + + + + + The process whose specific outcome is the progression of the metanephric distal tubule over time, from its formation to the mature structure. The metanephric distal tubule is a metanephric nephron tubule that begins at the metanephric macula densa and extends to the metanephric connecting tubule. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the metanephric loop of Henle over time, from its formation to the mature structure. The metanephric loop of Henle is a metanephric nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule in the metanephros. + mah + 2010-03-18T03:46:18Z + metanephric intermediate tubule development + biological_process + GO:0072236 + metanephric loop of Henle development + + + + + The process whose specific outcome is the progression of the metanephric loop of Henle over time, from its formation to the mature structure. The metanephric loop of Henle is a metanephric nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule in the metanephros. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the metanephric proximal tubule over time, from its formation to the mature structure. The metanephric proximal tubule is a metanephric nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle in the metanephros. It has a brush border epithelial morphology. + mah + 2010-03-18T03:46:54Z + biological_process + GO:0072237 + metanephric proximal tubule development + + + + + The process whose specific outcome is the progression of the metanephric proximal tubule over time, from its formation to the mature structure. The metanephric proximal tubule is a metanephric nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle in the metanephros. It has a brush border epithelial morphology. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a metanephric long nephron over time, from its formation to the mature structure. Long nephrons are associated with juxtamedullary glomeruli and extend into the inner medulla in the metanephros. + mah + 2010-03-18T03:48:23Z + biological_process + metanephric juxtamedullary nephron development + GO:0072238 + metanephric long nephron development + + + + + The process whose specific outcome is the progression of a metanephric long nephron over time, from its formation to the mature structure. Long nephrons are associated with juxtamedullary glomeruli and extend into the inner medulla in the metanephros. + GOC:mtg_kidney_jan10 + + + + + metanephric juxtamedullary nephron development + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The biological process whose specific outcome is the progression of a metanephric glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the metanephric glomerulus vasculature and ends with the mature structure. The metanephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the metanephric glomerulus. + mah + 2010-03-18T03:50:29Z + biological_process + glomerulus capillary development + GO:0072239 + metanephric glomerulus vasculature development + + + + + The biological process whose specific outcome is the progression of a metanephric glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the metanephric glomerulus vasculature and ends with the mature structure. The metanephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the metanephric glomerulus. + GOC:mtg_kidney_jan10 + + + + + glomerulus capillary development + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the metanephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The metanephric nephron epithelium is a tissue that covers the surface of a nephron in the metanephros. + mah + 2010-03-19T03:29:49Z + biological_process + GO:0072243 + metanephric nephron epithelium development + + + + + The process whose specific outcome is the progression of the metanephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The metanephric nephron epithelium is a tissue that covers the surface of a nephron in the metanephros. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the metanephric glomerular epithelium over time, from its formation to the mature structure. The metanephric glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus in the metanephros. The metanephric glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros. + mah + 2010-03-19T03:38:47Z + biological_process + GO:0072244 + metanephric glomerular epithelium development + + + + + The process whose specific outcome is the progression of the metanephric glomerular epithelium over time, from its formation to the mature structure. The metanephric glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus in the metanephros. The metanephric glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains 'feet' that interdigitate with the 'feet' of other glomerular epithelial cells in the metanephros. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the metanephric glomerular endothelium over time, from its formation to the mature structure. The metanephric glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus of the metanephros. + mah + 2010-03-30T02:42:26Z + biological_process + GO:0072264 + metanephric glomerular endothelium development + + + + + The process whose specific outcome is the progression of the metanephric glomerular endothelium over time, from its formation to the mature structure. The metanephric glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus of the metanephros. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the metanephric capsule are generated and organized. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. + mah + 2010-03-30T02:54:49Z + biological_process + GO:0072265 + metanephric capsule morphogenesis + + + + + The process in which the anatomical structures of the metanephric capsule are generated and organized. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The developmental process pertaining to the initial formation of a metanephric capsule from unspecified parts. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. + mah + 2010-03-30T02:56:35Z + biological_process + GO:0072266 + metanephric capsule formation + + + + + The developmental process pertaining to the initial formation of a metanephric capsule from unspecified parts. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + Any developmental process that results in the creation of defined areas or spaces within the metanephros to which cells respond and eventually are instructed to differentiate. + mah + 2010-03-30T03:06:30Z + metanephros pattern specification + biological_process + metanephros pattern formation + pattern formation involved in metanephros development + GO:0072268 + pattern specification involved in metanephros development + + + + + Any developmental process that results in the creation of defined areas or spaces within the metanephros to which cells respond and eventually are instructed to differentiate. + GOC:mtg_kidney_jan10 + + + + + metanephros pattern specification + GOC:mtg_kidney_jan10 + + + + + metanephros pattern formation + GOC:mtg_kidney_jan10 + + + + + pattern formation involved in metanephros development + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the metanephric long descending thin limb over time, from its formation to the mature structure. The metanephric long descending thin limb is the descending thin limb of a long nephron in the metanephros that has a squamous epithelial morphology. The long descending limb starts in the inner stripe of the outer medulla and extends into the inner medulla. + mah + 2010-03-30T03:12:05Z + biological_process + GO:0072269 + metanephric long descending thin limb development + + + + + The process whose specific outcome is the progression of the metanephric long descending thin limb over time, from its formation to the mature structure. The metanephric long descending thin limb is the descending thin limb of a long nephron in the metanephros that has a squamous epithelial morphology. The long descending limb starts in the inner stripe of the outer medulla and extends into the inner medulla. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a short nephron in the metanephros over time, from its formation to the mature structure. Short nephrons are associated with mid-cortical and superficial glomeruli, are situated entirely in the outer medulla, and have no thin ascending limb. + mah + 2010-03-30T03:15:18Z + biological_process + GO:0072270 + metanephric short nephron development + + + + + The process whose specific outcome is the progression of a short nephron in the metanephros over time, from its formation to the mature structure. Short nephrons are associated with mid-cortical and superficial glomeruli, are situated entirely in the outer medulla, and have no thin ascending limb. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the metanephric short descending thin limb over time, from its formation to the mature structure. The metanephric short descending thin limb is the descending thin limb of a short nephron in the metanephros that has a squamous epithelial morphology. + mah + 2010-03-30T03:16:25Z + biological_process + GO:0072271 + metanephric short descending thin limb development + + + + + The process whose specific outcome is the progression of the metanephric short descending thin limb over time, from its formation to the mature structure. The metanephric short descending thin limb is the descending thin limb of a short nephron in the metanephros that has a squamous epithelial morphology. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the metanephric nephron are generated and organized. A metanephric nephron is the functional unit of the metanephros. + mah + 2010-03-30T03:33:19Z + biological_process + GO:0072273 + metanephric nephron morphogenesis + + + + + The process in which the anatomical structures of the metanephric nephron are generated and organized. A metanephric nephron is the functional unit of the metanephros. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the metanephric glomerulus are generated and organized. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros. + mah + 2010-04-01T02:46:58Z + biological_process + GO:0072275 + metanephric glomerulus morphogenesis + + + + + The process in which the anatomical structures of the metanephric glomerulus are generated and organized. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the metanephric glomerulus vasculature are generated and organized. The metanephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the metanephric glomerulus. + mah + 2010-04-01T02:47:32Z + biological_process + GO:0072276 + metanephric glomerulus vasculature morphogenesis + + + + + The process in which the anatomical structures of the metanephric glomerulus vasculature are generated and organized. The metanephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the metanephric glomerulus. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to a metanephric glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts. + mah + 2010-04-01T02:47:56Z + biological_process + GO:0072277 + metanephric glomerular capillary formation + + + + + The process that gives rise to a metanephric glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the metanephric comma-shaped body is generated and organized. The metanephric comma-shaped body is the precursor structure to the metanephric S-shaped body that contributes to the morphogenesis of a nephron in the metanephros. + mah + 2010-04-01T03:14:42Z + biological_process + GO:0072278 + metanephric comma-shaped body morphogenesis + + + + + The process in which the metanephric comma-shaped body is generated and organized. The metanephric comma-shaped body is the precursor structure to the metanephric S-shaped body that contributes to the morphogenesis of a nephron in the metanephros. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of a metanephric nephron tubule are generated and organized. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros. + mah + 2010-04-01T03:25:11Z + biological_process + GO:0072282 + metanephric nephron tubule morphogenesis + + + + + The process in which the anatomical structures of a metanephric nephron tubule are generated and organized. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the metanephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the metanephric nephron epithelium, and is formed by the condensation of mesenchymal cells. + mah + 2010-04-01T03:28:00Z + biological_process + GO:0072283 + metanephric renal vesicle morphogenesis + + + + + The process in which the anatomical structures of the metanephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the metanephric nephron epithelium, and is formed by the condensation of mesenchymal cells. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the metanephric S-shaped body is generated and organized. The metanephric S-shaped body is the successor of the metanephric comma-shaped body that contributes to the morphogenesis of a nephron in the metanephros. + mah + 2010-04-01T03:41:36Z + biological_process + GO:0072284 + metanephric S-shaped body morphogenesis + + + + + The process in which the metanephric S-shaped body is generated and organized. The metanephric S-shaped body is the successor of the metanephric comma-shaped body that contributes to the morphogenesis of a nephron in the metanephros. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephric renal vesicle. + mah + 2010-04-01T03:43:31Z + biological_process + GO:0072285 + mesenchymal to epithelial transition involved in metanephric renal vesicle formation + + + + + A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephric renal vesicle. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the metanephric connecting tubule over time, from its formation to the mature structure. The metanephric connecting tubule is a tubular segment of the metanephric nephron; it connects the distal convoluted tubule to the collecting duct in the metanephros. + mah + 2010-04-09T03:30:09Z + metanephric connecting duct development + biological_process + GO:0072286 + metanephric connecting tubule development + + + + + The process whose specific outcome is the progression of the metanephric connecting tubule over time, from its formation to the mature structure. The metanephric connecting tubule is a tubular segment of the metanephric nephron; it connects the distal convoluted tubule to the collecting duct in the metanephros. + GOC:mtg_kidney_jan10 + + + + + metanephric connecting duct development + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of a metanephric distal tubule are generated and organized. The metanephric distal tubule is a metanephric nephron tubule that begins at the macula densa and extends to the metanephric connecting tubule. + mah + 2010-04-09T03:41:47Z + biological_process + GO:0072287 + metanephric distal tubule morphogenesis + + + + + The process in which the anatomical structures of a metanephric distal tubule are generated and organized. The metanephric distal tubule is a metanephric nephron tubule that begins at the macula densa and extends to the metanephric connecting tubule. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of a metanephric proximal tubule are generated and organized. The metanephric proximal tubule is a metanephric nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle in the metanephros. It has a brush border epithelial morphology. + mah + 2010-04-09T03:42:03Z + biological_process + GO:0072288 + metanephric proximal tubule morphogenesis + + + + + The process in which the anatomical structures of a metanephric proximal tubule are generated and organized. The metanephric proximal tubule is a metanephric nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle in the metanephros. It has a brush border epithelial morphology. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + + + + + + The developmental process pertaining to the initial formation of a metanephric nephron tubule from unspecified parts. A metanephric nephron tubule is an epithelial tube that is part of a nephron in the metanephros. + mah + 2010-04-09T03:47:44Z + biological_process + GO:0072289 + metanephric nephron tubule formation + + + + + The developmental process pertaining to the initial formation of a metanephric nephron tubule from unspecified parts. A metanephric nephron tubule is an epithelial tube that is part of a nephron in the metanephros. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + The orderly movement of epithelial cells within a renal tubule that contributes to metanephric nephron tubule morphogenesis. + mah + 2010-04-09T03:52:29Z + biological_process + GO:0072290 + epithelial cell migration involved in metanephric nephron tubule morphogenesis + + + + + The orderly movement of epithelial cells within a renal tubule that contributes to metanephric nephron tubule morphogenesis. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + The orderly movement of epithelial cells within a renal tubule that contributes to metanephric distal tubule morphogenesis. + mah + 2010-04-09T03:53:37Z + biological_process + GO:0072291 + epithelial cell migration involved in metanephric distal tubule morphogenesis + + + + + The orderly movement of epithelial cells within a renal tubule that contributes to metanephric distal tubule morphogenesis. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + The orderly movement of epithelial cells within a renal tubule that contributes to metanephric proximal tubule morphogenesis. + mah + 2010-04-09T03:54:28Z + biological_process + GO:0072292 + epithelial cell migration involved in metanephric proximal tubule morphogenesis + + + + + The orderly movement of epithelial cells within a renal tubule that contributes to metanephric proximal tubule morphogenesis. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + Any process that modulates the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros. + mah + 2010-04-09T05:03:14Z + biological_process + GO:0072298 + regulation of metanephric glomerulus development + + + + + Any process that modulates the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + Any process that decreases the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros. + mah + 2010-04-09T05:03:41Z + biological_process + GO:0072299 + negative regulation of metanephric glomerulus development + + + + + Any process that decreases the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + Any process that increases the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros. + mah + 2010-04-09T05:03:41Z + biological_process + GO:0072300 + positive regulation of metanephric glomerulus development + + + + + Any process that increases the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a glomerular epithelial cell over time, from its formation to the mature structure. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells. + mah + 2010-04-09T06:47:31Z + biological_process + GO:0072310 + glomerular epithelial cell development + + + + + The process whose specific outcome is the progression of a glomerular epithelial cell over time, from its formation to the mature structure. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of a glomerular epithelial cell. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells. + mah + 2010-04-09T06:49:21Z + biological_process + GO:0072311 + glomerular epithelial cell differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized features of a glomerular epithelial cell. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group. + mah + 2010-11-02T04:41:55Z + biological_process + GO:0072329 + monocarboxylic acid catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group. + GOC:mah + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group. + mah + 2010-11-02T04:51:32Z + monocarboxylic acid anabolism + monocarboxylic acid biosynthesis + monocarboxylic acid formation + monocarboxylic acid synthesis + biological_process + GO:0072330 + monocarboxylic acid biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group. + GOC:mah + + + + + monocarboxylic acid anabolism + GOC:mah + + + + + monocarboxylic acid biosynthesis + GOC:mah + + + + + monocarboxylic acid formation + GOC:mah + + + + + monocarboxylic acid synthesis + GOC:mah + + + + + + + + + + + + + + + + + + + The directed movement of modified amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + mah + 2010-11-04T12:18:23Z + amino acid derivative transport + biological_process + GO:0072337 + modified amino acid transport + + + + + The directed movement of modified amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:mah + + + + + + + + + + + + + + + + + + + + Binding to a modified amino acid. + mah + 2010-11-04T05:45:32Z + amino acid derivative binding + molecular_function + GO:0072341 + modified amino acid binding + + + + + Binding to a modified amino acid. + GOC:mah + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the circulatory system over time, from its formation to the mature structure. The circulatory system is the organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis. + mah + 2010-11-16T11:27:39Z + GO:0072358 + cardiovascular system development + biological_process + GO:0072359 + + circulatory system development + + + + + The process whose specific outcome is the progression of the circulatory system over time, from its formation to the mature structure. The circulatory system is the organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis. + GOC:mah + UBERON:0001009 + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the vascular cord over time from its initial formation until its mature state. The vascular cord is the primordial vasculature that will develop into blood vessels by the process of tubulogenesis. + mah + 2010-11-16T11:46:55Z + biological_process + GO:0072360 + vascular cord development + + + + + The progression of the vascular cord over time from its initial formation until its mature state. The vascular cord is the primordial vasculature that will develop into blood vessels by the process of tubulogenesis. + GOC:mah + PMID:7084422 + ZFA:0005077 + + + + + + + + + + + + + + + + + + + + + + + + The directed movement of an organelle along a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination. + mah + 2010-12-01T04:59:11Z + microtubule-based organelle localization + biological_process + GO:0072384 + organelle transport along microtubule + + + + + The directed movement of an organelle along a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination. + GOC:mah + + + + + microtubule-based organelle localization + GOC:rl + + + + + + + + + + + + + + + + + + + + + Any process involved in the maintenance of an internal steady state of divalent cations at the level of a cell. + mah + 2010-12-16T01:25:40Z + biological_process + GO:0072503 + Note that this term was split from 'cellular di-, tri-valent inorganic cation homeostasis ; GO:0030005' (sibling term 'cellular trivalent inorganic cation homeostasis' ; GO:0072504'). + cellular divalent inorganic cation homeostasis + + + + + Any process involved in the maintenance of an internal steady state of divalent cations at the level of a cell. + GOC:mah + + + + + + + + + + + + + + + + + + + + + Any process involved in the maintenance of an internal steady state of divalent cations within an organism or cell. + mah + 2010-12-16T03:22:48Z + biological_process + GO:0072507 + Note that this term was split from 'di-, tri-valent inorganic cation homeostasis ; GO:0055066' (sibling term 'trivalent inorganic cation homeostasis' ; GO:0072508'). + divalent inorganic cation homeostasis + + + + + Any process involved in the maintenance of an internal steady state of divalent cations within an organism or cell. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + + The reproductive developmental process whose specific outcome is the progression of the seminiferous tubule over time, from its formation to the mature structure. Seminiferous tubules are ducts located in the testicles, and are the specific location of meiosis, and the subsequent creation of gametes, namely spermatozoa. + mah + 2011-01-04T12:50:36Z + biological_process + GO:0072520 + seminiferous tubule development + + + + + The reproductive developmental process whose specific outcome is the progression of the seminiferous tubule over time, from its formation to the mature structure. Seminiferous tubules are ducts located in the testicles, and are the specific location of meiosis, and the subsequent creation of gametes, namely spermatozoa. + GOC:BHF + GOC:mah + UBERON:0001343 + + + + + + + + + + + + + + + + + + + + A change in the morphology or behavior of a fibroblast resulting from exposure to an activating factor such as a cellular or soluble ligand. + mah + 2011-01-14T04:35:08Z + biological_process + GO:0072537 + fibroblast activation + + + + + A change in the morphology or behavior of a fibroblast resulting from exposure to an activating factor such as a cellular or soluble ligand. + CL:0000057 + GOC:BHF + GOC:mah + + + + + + + + + + + + + + + + + + + The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the liver. + mah + 2011-02-02T03:37:50Z + biological_process + GO:0072575 + epithelial cell proliferation involved in liver morphogenesis + + + + + The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the liver. + GOC:BHF + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the liver are generated and organized. + mah + 2011-02-02T03:41:30Z + biological_process + GO:0072576 + liver morphogenesis + + + + + The process in which the anatomical structures of the liver are generated and organized. + GOC:mah + + + + + + + + + + + + + + + + + + + + The directed movement of a protein to a specific location on or in an organelle. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle. + mah + 2011-02-14T01:56:51Z + establishment of protein localisation to organelle + biological_process + GO:0072594 + establishment of protein localization to organelle + + + + + The directed movement of a protein to a specific location on or in an organelle. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle. + GOC:mah + + + + + establishment of protein localisation to organelle + GOC:mah + + + + + + + + + + + + + + + + + + + + A process in which a protein is transported to, or maintained in, a specific location in a membrane. + mah + 2011-02-14T02:35:18Z + protein localisation in membrane + protein localization in membrane + biological_process + GO:0072657 + + protein localization to membrane + + + + + A process in which a protein is transported to, or maintained in, a specific location in a membrane. + GOC:mah + + + + + protein localisation in membrane + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane. + tb + 2009-07-10T10:29:23Z + GO:0072661 + GO:0090002 + biological_process + protein localisation in plasma membrane + protein localization in plasma membrane + protein targeting to plasma membrane + protein-plasma membrane targeting + GO:0072659 + + + protein localization to plasma membrane + + + + + A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane. + GOC:mah + + + + + protein localisation in plasma membrane + GOC:mah + + + + + protein-plasma membrane targeting + GOC:mah + + + + + + + + + + + + + + + + + + + A process in which a protein is transported to, or maintained at, a location in a vacuole. + mah + 2011-02-14T02:55:35Z + protein localisation to vacuole + biological_process + GO:0072665 + protein localization to vacuole + + + + + A process in which a protein is transported to, or maintained at, a location in a vacuole. + GOC:ecd + + + + + protein localisation to vacuole + GOC:mah + + + + + + + + + + + + + + + + + + + + The directed movement of a protein to a specific location in a vacuole. + mah + 2011-02-14T02:56:29Z + establishment of protein localisation to vacuole + biological_process + GO:0072666 + establishment of protein localization to vacuole + + + + + The directed movement of a protein to a specific location in a vacuole. + GOC:mah + + + + + establishment of protein localisation to vacuole + GOC:mah + + + + + + + + + + + + + + + + + + + + The movement of a lymphocyte within or between different tissues and organs of the body. + mah + 2011-02-22T03:38:12Z + biological_process + GO:0072676 + lymphocyte migration + + + + + The movement of a lymphocyte within or between different tissues and organs of the body. + CL:0000542 + GOC:BHF + GOC:mah + + + + + + + + + + + + + + + + + + + + The movement of a T cell within or between different tissues and organs of the body. + mah + 2011-02-22T03:40:40Z + T lymphocyte migration + T-cell migration + T-lymphocyte migration + biological_process + GO:0072678 + T cell migration + + + + + The movement of a T cell within or between different tissues and organs of the body. + CL:0000084 + GOC:BHF + GOC:mah + + + + + T lymphocyte migration + CL:0000084 + + + + + T-cell migration + CL:0000084 + + + + + T-lymphocyte migration + CL:0000084 + + + + + + + + + + + + + + + + + + + + The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development. + mah + 2011-02-22T03:47:51Z + thymic lymphocyte migration + biological_process + immature T cell migration + immature T lymphocyte migration + immature T-cell migration + immature T-lymphocyte migration + GO:0072679 + thymocyte migration + + + + + The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development. + CL:0000893 + GOC:BHF + GOC:mah + + + + + thymic lymphocyte migration + CL:0000893 + + + + + immature T cell migration + CL:0000893 + + + + + immature T lymphocyte migration + CL:0000893 + + + + + immature T-cell migration + CL:0000893 + + + + + immature T-lymphocyte migration + CL:0000893 + + + + + + + + + + + + + + + + + + + + A process in which a protein is transported to, or maintained in, the cell cortex. + mah + 2012-04-11T01:16:33Z + protein localisation to cell cortex + biological_process + GO:0072697 + protein localization to cell cortex + + + + + A process in which a protein is transported to, or maintained in, the cell cortex. + GOC:mah + + + + + protein localisation to cell cortex + GOC:mah + + + + + + + + + + + + + + + + + + + A cellular protein localization process in which a protein is transported to, or maintained at, a location within the microtubule cytoskeleton. + mah + 2012-04-11T01:19:35Z + protein localisation to microtubule cytoskeleton + biological_process + GO:0072698 + protein localization to microtubule cytoskeleton + + + + + A cellular protein localization process in which a protein is transported to, or maintained at, a location within the microtubule cytoskeleton. + GOC:mah + + + + + protein localisation to microtubule cytoskeleton + GOC:mah + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. + dhl + 2009-04-22T04:30:52Z + biological_process + GO:0080090 + regulation of primary metabolic process + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism. + PMID:19211694 + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). + dhl + 2009-05-06T04:51:28Z + biological_process + GO:0080134 + + Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. + regulation of response to stress + + + + + Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation). + GOC:dhl + + + + + + + + + + + + + + + + + + + Any process involved in the maintenance of an internal steady state of amino acid within an organism or cell. + dhl + 2010-01-27T04:47:27Z + biological_process + GO:0080144 + amino acid homeostasis + + + + + Any process involved in the maintenance of an internal steady state of amino acid within an organism or cell. + PMID:19955263 + + + + + + + + + + + + + + + + + + + + Any process that modulates the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy). + dhl + 2010-09-01T03:44:27Z + biological_process + GO:0080154 + regulation of fertilization + + + + + Any process that modulates the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy). + GOC:DHL + PMID:20478994 + + + + + + + + + + + + + + + + + + + + + The aggregation, arrangement and bonding together of the extracellular matrix. + jl + 2010-07-14T12:52:49Z + biological_process + GO:0085029 + extracellular matrix assembly + + + + + The aggregation, arrangement and bonding together of the extracellular matrix. + GOC:jl + + + + + + + + + + + + + + + + + + + An G protein-coupled receptor signaling pathway which contributes to a circulatory system process carried out by the heart. + bf + 2012-03-19T01:28:23Z + G-protein coupled receptor signaling pathway involved in heart process + G-protein coupled receptor signalling pathway involved in heart process + GPCR signaling pathway involved in cardiac process + GPCR signaling pathway involved in heart process + biological_process + GO:0086103 + G protein-coupled receptor signaling pathway involved in heart process + + + + + An G protein-coupled receptor signaling pathway which contributes to a circulatory system process carried out by the heart. + GOC:BHF + GOC:mtg_cardiac_conduct_nov11 + PMID:17376402 + + + + + G-protein coupled receptor signaling pathway involved in heart process + GOC:bf + + + + + G-protein coupled receptor signalling pathway involved in heart process + GOC:bf + + + + + GPCR signaling pathway involved in cardiac process + GOC:bf + + + + + GPCR signaling pathway involved in heart process + GOC:bf + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the hypoblast over time, from its formation to the mature structure. The hypoblast is a tissue formed from the inner cell mass that lies beneath the epiblast. + tb + 2009-07-29T10:25:54Z + biological_process + GO:0090008 + hypoblast development + + + + + The process whose specific outcome is the progression of the hypoblast over time, from its formation to the mature structure. The hypoblast is a tissue formed from the inner cell mass that lies beneath the epiblast. + GOC:dph + GOC:sdb_2009 + GOC:tb + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The developmental process pertaining to the initial formation of the primitive streak from unspecified parts. The primitive streak is a ridge of cells running along the midline of the embryo where the mesoderm ingresses. It defines the anterior-posterior axis. + tb + 2009-07-29T10:31:31Z + biological_process + GO:0090009 + primitive streak formation + + + + + The developmental process pertaining to the initial formation of the primitive streak from unspecified parts. The primitive streak is a ridge of cells running along the midline of the embryo where the mesoderm ingresses. It defines the anterior-posterior axis. + GOC:dph + GOC:sdb_2009 + GOC:tb + + + + + + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones. + tb + 2009-08-03T10:38:27Z + biological_process + GO:0090030 + regulation of steroid hormone biosynthetic process + + + + + Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones. + GOC:dph + GOC:tb + + + + + + + + + + + Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones. + tb + 2009-08-03T10:40:32Z + biological_process + GO:0090031 + positive regulation of steroid hormone biosynthetic process + + + + + Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones. + GOC:dph + GOC:tb + + + + + + + + + + + Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones. + tb + 2009-08-03T10:41:35Z + biological_process + GO:0090032 + negative regulation of steroid hormone biosynthetic process + + + + + Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones. + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + + + + + + Any process that increases the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell. + tb + 2009-08-12T11:33:09Z + biological_process + GO:0090063 + positive regulation of microtubule nucleation + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that increases the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell. + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. + tb + 2009-09-09T11:39:52Z + biological_process + GO:0090068 + positive regulation of cell cycle process + + + + + Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + tb + 2009-10-23T11:21:38Z + biological_process + GO:0090087 + regulation of peptide transport + + + + + Any process that modulates the frequency, rate or extent of the directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + + + + + + + + The progression of the cochlea over time from its formation to the mature structure. The cochlea is the snail-shaped portion of the inner ear that is responsible for the detection of sound. + tb + 2009-11-18T11:42:15Z + biological_process + GO:0090102 + cochlea development + + + + + The progression of the cochlea over time from its formation to the mature structure. The cochlea is the snail-shaped portion of the inner ear that is responsible for the detection of sound. + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the cochlea is generated and organized. + tb + 2009-11-18T11:45:11Z + biological_process + GO:0090103 + cochlea morphogenesis + + + + + The process in which the cochlea is generated and organized. + GOC:dph + GOC:tb + + + + + + + + + The process in which the population of cells that make up a tissue undergo directed movement. + tb + 2009-12-07T03:13:55Z + biological_process + GO:0090130 + tissue migration + + + + + The process in which the population of cells that make up a tissue undergo directed movement. + GOC:ascb_2009 + GOC:dph + GOC:tb + + + + + + + + + + + + + + + The process in which the population of cells that make up a mesenchyme undergo directed movement. + tb + 2009-12-07T03:15:17Z + biological_process + GO:0090131 + mesenchyme migration + + + + + The process in which the population of cells that make up a mesenchyme undergo directed movement. + GOC:ascb_2009 + GOC:dph + GOC:tb + + + + + + + + + The process in which the population of cells that make up an epithelium undergo directed movement. + tb + 2009-12-07T03:19:34Z + biological_process + GO:0090132 + epithelium migration + + + + + The process in which the population of cells that make up an epithelium undergo directed movement. + GOC:ascb_2009 + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + Any cell-cell adhesion process that modulates the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins. + tb + 2009-12-08T02:05:00Z + regulation of actin cytoskeleton organisation by cell-cell adhesion + biological_process + GO:0090138 + regulation of actin cytoskeleton organization by cell-cell adhesion + + + + + Any cell-cell adhesion process that modulates the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins. + GOC:ascb_2009 + GOC:dph + GOC:tb + + + + + regulation of actin cytoskeleton organisation by cell-cell adhesion + GOC:mah + + + + + + + + + + + + + + + + + + + + The directed movement of a protein to a specific location in a membrane. + tb + 2009-12-08T03:18:51Z + establishment of protein localisation in membrane + establishment of protein localization in membrane + biological_process + GO:0090150 + establishment of protein localization to membrane + + + + + The directed movement of a protein to a specific location in a membrane. + GOC:ascb_2009 + GOC:dph + GOC:tb + + + + + establishment of protein localisation in membrane + GOC:mah + + + + + + + + + + + + + + + + + + + + The specification and formation of anisotropic intracellular organization of an epithelial cell. + tb + 2009-12-08T08:58:27Z + biological_process + GO:0090162 + establishment of epithelial cell polarity + + + + + The specification and formation of anisotropic intracellular organization of an epithelial cell. + GOC:ascb_2009 + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + The reformation of the Golgi following its breakdown and partitioning contributing to Golgi inheritance. + tb + 2009-12-08T09:15:11Z + biological_process + GO:0090168 + Golgi reassembly + + + + + The reformation of the Golgi following its breakdown and partitioning contributing to Golgi inheritance. + GOC:ascb_2009 + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + Any process that modulates the rate, frequency or extent of Golgi inheritance. Golgi inheritance is the partitioning of Golgi apparatus between daughter cells at cell division. + tb + 2009-12-11T10:21:59Z + biological_process + GO:0090170 + regulation of Golgi inheritance + + + + + Any process that modulates the rate, frequency or extent of Golgi inheritance. Golgi inheritance is the partitioning of Golgi apparatus between daughter cells at cell division. + GOC:ascb_2009 + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the structures of a chondrocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a chondrocyte. + tb + 2009-12-11T10:36:02Z + biological_process + GO:0090171 + chondrocyte morphogenesis + + + + + The process in which the structures of a chondrocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a chondrocyte. + GOC:ascb_2009 + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + + + The joining of two lipid bilayers to form a single organelle membrane. + tb + 2009-12-11T11:44:58Z + biological_process + GO:0090174 + organelle membrane fusion + + + + + The joining of two lipid bilayers to form a single organelle membrane. + GOC:ascb_2009 + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + Any process that modulates the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. + tb + 2009-12-18T10:50:56Z + biological_process + regulation of nephrogenesis + GO:0090183 + regulation of kidney development + + + + + Any process that modulates the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. + GOC:dph + GOC:tb + GOC:yaf + + + + + regulation of nephrogenesis + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + Any process that increases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. + tb + 2009-12-18T10:52:01Z + biological_process + positive regulation of nephrogenesis + GO:0090184 + positive regulation of kidney development + + + + + Any process that increases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. + GOC:dph + GOC:tb + GOC:yaf + + + + + positive regulation of nephrogenesis + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + Any process that decreases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. + tb + 2009-12-18T10:58:45Z + biological_process + negative regulation of nephrogenesis + GO:0090185 + negative regulation of kidney development + + + + + Any process that decreases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine. + GOC:dph + GOC:tb + GOC:yaf + + + + + negative regulation of nephrogenesis + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + + Any process that modulates the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules. + tb + 2009-12-18T11:11:17Z + biological_process + GO:0090189 + regulation of branching involved in ureteric bud morphogenesis + + + + + Any process that modulates the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules. + GOC:dph + GOC:tb + GOC:yaf + + + + + + + + + + + + + + + + + + + Any process that increases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules. + tb + 2009-12-18T11:11:17Z + biological_process + GO:0090190 + positive regulation of branching involved in ureteric bud morphogenesis + + + + + Any process that increases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules. + GOC:dph + GOC:tb + GOC:yaf + + + + + + + + + + + + + + + + + + + Any process that decreases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules. + tb + 2009-12-18T11:11:17Z + biological_process + GO:0090191 + negative regulation of branching involved in ureteric bud morphogenesis + + + + + Any process that decreases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules. + GOC:dph + GOC:tb + GOC:yaf + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney. + tb + 2009-12-18T11:17:13Z + biological_process + GO:0090192 + regulation of glomerulus development + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney. + GOC:dph + GOC:tb + GOC:yaf + + + + + + + + + + + + + + + + + + + + Any process that increases the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney. + tb + 2009-12-18T11:17:13Z + biological_process + GO:0090193 + positive regulation of glomerulus development + + + + + Any process that increases the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney. + GOC:dph + GOC:tb + GOC:yaf + + + + + + + + + + + + + + + + + + + + Any process that decreases the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney. + tb + 2009-12-18T11:17:13Z + biological_process + GO:0090194 + negative regulation of glomerulus development + + + + + Any process that decreases the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney. + GOC:dph + GOC:tb + GOC:yaf + + + + + + + + + + + + + + + + + + + + + + + + + + The increase in size or mass of the spongiotrophoblast layer of the placenta where the increase in size or mass contributes to the progression of that layer over time from its formation to its mature state. + tb + 2010-01-08T12:10:44Z + biological_process + GO:0090214 + spongiotrophoblast layer developmental growth + + + + + The increase in size or mass of the spongiotrophoblast layer of the placenta where the increase in size or mass contributes to the progression of that layer over time from its formation to its mature state. + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + The process in which the population of cells that make up a wing epithelium undergo directed movement and contribute to imaginal disc-derived morphogenesis. + tb + 2010-01-22T11:40:46Z + biological_process + GO:0090252 + epithelium migration involved in imaginal disc-derived wing morphogenesis + + + + + The process in which the population of cells that make up a wing epithelium undergo directed movement and contribute to imaginal disc-derived morphogenesis. + GOC:ascb_2009 + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to imaginal disc-derived wing morphogenesis. + tb + 2010-01-22T11:40:46Z + biological_process + GO:0090255 + cell proliferation involved in imaginal disc-derived wing morphogenesis + + + + + The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to imaginal disc-derived wing morphogenesis. + GOC:ascb_2009 + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate, or extent of the multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to imaginal disc-derived wing morphogenesis. + tb + 2010-01-22T11:40:46Z + biological_process + GO:0090256 + regulation of cell proliferation involved in imaginal disc-derived wing morphogenesis + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate, or extent of the multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to imaginal disc-derived wing morphogenesis. + GOC:ascb_2009 + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of a muscle system process, a multicellular organismal process carried out by any of the organs or tissues in a muscle system. + tb + 2010-02-03T11:48:13Z + biological_process + GO:0090257 + regulation of muscle system process + + + + + Any process that modulates the frequency, rate or extent of a muscle system process, a multicellular organismal process carried out by any of the organs or tissues in a muscle system. + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + Any process that modulates the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas. + tb + 2010-02-05T02:54:14Z + biological_process + GO:0090273 + regulation of somatostatin secretion + + + + + Any process that modulates the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas. + GOC:BHF + + + + + + + + + + + + + + + + + + + + + Any process that increases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas. + tb + 2010-02-05T02:54:14Z + biological_process + GO:0090274 + positive regulation of somatostatin secretion + + + + + Any process that increases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas. + GOC:BHF + + + + + + + + + + + + + + + + + + + + + Any process that decreases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas. + tb + 2010-02-05T02:54:14Z + biological_process + GO:0090275 + negative regulation of somatostatin secretion + + + + + Any process that decreases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas. + GOC:BHF + + + + + + + + + + + + + + + + + + + + + Any process that modulates the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules. + tb + 2010-02-05T02:56:39Z + biological_process + GO:0090276 + regulation of peptide hormone secretion + + + + + Any process that modulates the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules. + GOC:tb + + + + + + + + + + + + + + + + + + + + + + Any process that increases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules. + tb + 2010-02-05T02:56:39Z + biological_process + GO:0090277 + positive regulation of peptide hormone secretion + + + + + Any process that increases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules. + GOC:tb + + + + + + + + + + + + + + + + + + + + + + Any process that decreases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules. + tb + 2010-02-05T02:56:39Z + biological_process + GO:0090278 + negative regulation of peptide hormone secretion + + + + + Any process that decreases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules. + GOC:tb + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds. + tb + 2010-03-12T04:08:26Z + biological_process + GO:0090299 + regulation of neural crest formation + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds. + GOC:tb + + + + + + + + + + + + + + + + + + + Any process that increases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes. + tb + 2010-03-12T04:08:26Z + biological_process + GO:0090300 + positive regulation of neural crest formation + + + + + Any process that increases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes. + GOC:tb + + + + + + + + + + + + + + + + + + + Any process that decreases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes. + tb + 2010-03-12T04:08:26Z + biological_process + GO:0090301 + negative regulation of neural crest formation + + + + + Any process that decreases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes. + GOC:tb + + + + + + + + + + + + + + + + + + + + + Any process that increases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury. + tb + 2010-03-22T02:12:03Z + biological_process + GO:0090303 + positive regulation of wound healing + + + + + Any process that increases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury. + GOC:BHF + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells. + tb + 2010-04-16T03:45:07Z + biological_process + GO:0090316 + positive regulation of intracellular protein transport + + + + + Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells. + GOC:tb + + + + + + + + + + + + + + + + + + + + + + + + + Any process that decreases the frequency, rate or extent of the directed movement of proteins within cells. + tb + 2010-04-16T03:45:07Z + biological_process + GO:0090317 + negative regulation of intracellular protein transport + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that decreases the frequency, rate or extent of the directed movement of proteins within cells. + GOC:tb + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement. + tb + 2010-05-14T10:24:29Z + biological_process + GO:0090325 + regulation of locomotion involved in locomotory behavior + + + + + Any process that modulates the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement. + GOC:dph + GOC:kmv + GOC:tb + + + + + + + + + + + + + + + + + + + + + + Any process that increases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement. + tb + 2010-05-14T10:26:58Z + biological_process + GO:0090326 + positive regulation of locomotion involved in locomotory behavior + + + + + Any process that increases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement. + GOC:dph + GOC:kmv + GOC:tb + + + + + + + + + + + + + + + + + + + + + + Any process that decreases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement. + tb + 2010-05-14T10:26:58Z + biological_process + GO:0090327 + negative regulation of locomotion involved in locomotory behavior + + + + + Any process that decreases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement. + GOC:dph + GOC:kmv + GOC:tb + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the rate, frequency, or extent of olfactory learning. Olfactory learning is any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue. + tb + 2010-05-14T10:37:22Z + biological_process + GO:0090328 + regulation of olfactory learning + + + + + Any process that modulates the rate, frequency, or extent of olfactory learning. Olfactory learning is any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue. + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + Any process that modulates the rate, frequency, or extent of brown fat cell differentiation. Brown fat cell differentiation is the process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria. + tb + 2010-06-01T03:16:57Z + biological_process + GO:0090335 + regulation of brown fat cell differentiation + + + + + Any process that modulates the rate, frequency, or extent of brown fat cell differentiation. Brown fat cell differentiation is the process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria. + GOC:tb + + + + + + + + + + + + + + + + + + + Any process that increases the rate, frequency, or extent of brown fat cell differentiation. Brown fat cell differentiation is the process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria. + tb + 2010-06-01T03:19:26Z + biological_process + GO:0090336 + positive regulation of brown fat cell differentiation + + + + + Any process that increases the rate, frequency, or extent of brown fat cell differentiation. Brown fat cell differentiation is the process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria. + GOC:BHF + + + + + + + + + + + + + + + + + + + + A process in which a protein is transported to, or maintained at, a location within a nuclear envelope. + tb + 2012-07-30T01:50:41Z + protein localization in nuclear envelope + biological_process + GO:0090435 + protein localization to nuclear envelope + + + + + A process in which a protein is transported to, or maintained at, a location within a nuclear envelope. + GOC:tb + + + + + + + + + + + + + + + + + + + + Any process involved in the maintenance of an internal steady state of glutamate within an organism or cell. + tb + 2012-09-24T14:22:02Z + biological_process + GO:0090461 + glutamate homeostasis + + + + + Any process involved in the maintenance of an internal steady state of glutamate within an organism or cell. + GOC:tb + + + + + + + + + + + + + + + + + + + + + + + + + + + + The directed movement of catecholamine into a cell. + tb + 2012-10-17T11:06:17Z + biological_process + GO:0090493 + catecholamine uptake + + + + + The directed movement of catecholamine into a cell. + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + + + + + + + + + The directed movement of dopamine into a cell. + tb + 2012-10-17T11:12:09Z + biological_process + GO:0090494 + dopamine uptake + + + + + The directed movement of dopamine into a cell. + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + The migration of mesenchymal tissue that contributes to the formation of a limb bud. + tb + 2012-10-17T12:04:20Z + biological_process + GO:0090496 + mesenchyme migration involved in limb bud formation + + + + + The migration of mesenchymal tissue that contributes to the formation of a limb bud. + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + The orderly movement of a mesenchymal cell from one site to another, often during the development of a multicellular organism. + tb + 2012-10-17T12:08:17Z + biological_process + GO:0090497 + mesenchymal cell migration + + + + + The orderly movement of a mesenchymal cell from one site to another, often during the development of a multicellular organism. + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + The orderly movement of a podocyte from one site to another, often during the development of a multicellular organism or multicellular structure. A podocyte is a specialized kidney epithelial cell. + https://github.com/geneontology/go-ontology/issues/23000 + tb + 2013-01-08T11:08:57Z + glomerular visceral epithelial cell migration + biological_process + GO:0090521 + podocyte cell migration + + + + + The orderly movement of a podocyte from one site to another, often during the development of a multicellular organism or multicellular structure. A podocyte is a specialized kidney epithelial cell. + GOC:pm + PMID:21402783 + + + + + + + + + + The immediate defensive reaction by vertebrate tissue to injury caused by chemical or physical agents. + tb + 2014-08-12T12:13:53Z + biological_process + GO:0090594 + inflammatory response to wounding + + + + + The immediate defensive reaction by vertebrate tissue to injury caused by chemical or physical agents. + GOC:add + + + + + + + + + + + + + + + + + + + + + + + + + + Morphogenesis of a sensory organ. A sensory organ is defined as a tissue or set of tissues that work together to receive and transmit signals from external or internal stimuli. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. + tb + 2014-08-22T13:23:20Z + biological_process + GO:0090596 + sensory organ morphogenesis + + + + + Morphogenesis of a sensory organ. A sensory organ is defined as a tissue or set of tissues that work together to receive and transmit signals from external or internal stimuli. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions. + GOC:kmv + ISBN:978-0199210893 + + + + + + + + + + + + + + + + + + + + + + + + + + The processes by which anatomical structures that are only present in the male organism are generated and organized. + tb + 2014-08-22T13:29:45Z + biological_process + GO:0090598 + male anatomical structure morphogenesis + + + + + The processes by which anatomical structures that are only present in the male organism are generated and organized. + GOC:kmv + GOC:tb + + + + + + + + + + + + + + + Any process of the immune system that can contribute to the formation of immunological memory or an immune response based upon activation of immunological memory. + tb + 2016-11-11T12:20:30Z + biological_process + GO:0090713 + immunological memory process + + + + + Any process of the immune system that can contribute to the formation of immunological memory or an immune response based upon activation of immunological memory. + GOC:add + PMID:26086132 + PMID:26831526 + + + + + + + + + Any immunological memory process that can contribute to the formation of immunological memory. + tb + 2016-11-11T12:25:47Z + biological_process + GO:0090715 + immunological memory formation process + + + + + Any immunological memory process that can contribute to the formation of immunological memory. + GOC:add + PMID:26086132 + PMID:26831526 + + + + + + + + + + + + + + + + + + + The component of the pigment granule membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. + tb + 2017-05-16T17:48:35Z + cellular_component + GO:0090740 + integral component of pigment granule membrane + + + + + The component of the pigment granule membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. + PMID:11294610 + + + + + + + + + + + + + + + + + + + + Any membrane that is part of a pigment granule. + tb + 2017-05-16T22:33:39Z + cellular_component + GO:0090741 + pigment granule membrane + + + + + Any membrane that is part of a pigment granule. + PMID:11294610 + + + + + + + + + + + + + + + + + + + + + + + + + All of the contents of a cilium, excluding the plasma membrane surrounding the cilium. + pr + 2011-03-23T01:52:31Z + cilium plasm + microtubule-based flagellar matrix + microtubule-based flagellum matrix + cellular_component + cilial cytoplasm + ciliary cytoplasm + cilium cytoplasm + microtubule-based flagellar cytoplasm + microtubule-based flagellum cytoplasm + GO:0097014 + Note that we deem cilium and microtubule-based flagellum to be equivalent. Also, researchers consider the composition of both the plasm and the membrane of the cilium to be detectably different from that in the non-ciliary cytosol and plasma membrane (e.g. in terms of calcium ion concentration, membrane lipid composition, and more). For this reason, the term "ciliary plasm" is not linked to "cytoplasm". + ciliary plasm + + + + + All of the contents of a cilium, excluding the plasma membrane surrounding the cilium. + GOC:BHF + GOC:cilia + GOC:dos + PMID:17895364 + + + + + + + + + + + + + + + + + + + Formation of dendrites, branched cellular projections (or cytoplasmic extension) that are extended from the surface of a dendritic immune cell, and which enable the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells. + pr + 2011-03-31T04:52:53Z + dendritic extension + biological_process + GO:0097026 + Note that dendrites of dendritic cells should not be confused with neuronal cell dendrites, which process electrical signals. + dendritic cell dendrite assembly + + + + + Formation of dendrites, branched cellular projections (or cytoplasmic extension) that are extended from the surface of a dendritic immune cell, and which enable the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells. + CL:0000451 + GOC:BHF + PMID:12200351 + + + + + + + + + + + + + + + + + + + + The process in which a precursor cell type acquires the specialized features of a dendritic cell. A dendritic cell is a leukocyte of dendritic lineage specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. + pr + 2011-04-01T10:08:42Z + biological_process + GO:0097028 + Note that immunologists typically use the word 'maturation' to refer to dendritic cells undergoing the process that GO describes as 'cell differentiation'. + dendritic cell differentiation + + + + + The process in which a precursor cell type acquires the specialized features of a dendritic cell. A dendritic cell is a leukocyte of dendritic lineage specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation. + CL:0000451 + GOC:pr + + + + + + + + + + + + + + + + + + + A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroid hormone stimulus. + pr + 2011-06-14T05:01:18Z + response to thyroid hormone stimulus + biological_process + GO:0097066 + response to thyroid hormone + + + + + A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroid hormone stimulus. + GOC:sjw + PMID:9916872 + + + + + response to thyroid hormone stimulus + GOC:dos + + + + + + + + + + + + + + + + + + + A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroid hormone stimulus. + pr + 2011-06-14T05:02:47Z + biological_process + GO:0097067 + cellular response to thyroid hormone stimulus + + + + + A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroid hormone stimulus. + GOC:sjw + PMID:9916872 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which any suture between cranial and/or facial bones is generated and organized. + pr + 2011-07-05T02:51:54Z + biological_process + GO:0097094 + craniofacial suture morphogenesis + + + + + The process in which any suture between cranial and/or facial bones is generated and organized. + GOC:pr + GOC:sl + Wikipedia:Cranial_sutures + Wikipedia:Head_and_neck_anatomy#Musculoskeletal_system + + + + + + + + + + + + + + + + + + + + The process in which the frontonasal suture, between frontal and nasal bones, is generated and organized. + pr + 2011-07-05T02:57:46Z + nasofrontal suture morphogenesis + biological_process + GO:0097095 + frontonasal suture morphogenesis + + + + + The process in which the frontonasal suture, between frontal and nasal bones, is generated and organized. + GOC:pr + GOC:sl + PMID:12416537 + Wikipedia:Cranial_sutures + Wikipedia:Head_and_neck_anatomy#Musculoskeletal_system + + + + + + + + + + + + + + + + + + + + The process in which any suture between facial bones is generated and organized. + pr + 2011-07-05T03:06:27Z + biological_process + GO:0097096 + facial suture morphogenesis + + + + + The process in which any suture between facial bones is generated and organized. + GOC:pr + GOC:sl + Wikipedia:Cranial_sutures + Wikipedia:Head_and_neck_anatomy#Musculoskeletal_system + + + + + + + + + + + + + + + + + + + + The process in which the nasal suture is generated and organized. + pr + 2011-07-05T03:09:04Z + internasal suture morphogenesis + biological_process + GO:0097097 + nasal suture morphogenesis + + + + + The process in which the nasal suture is generated and organized. + GOC:pr + GOC:sl + Wikipedia:Cranial_sutures + Wikipedia:Head_and_neck_anatomy#Musculoskeletal_system + + + + + + + + + + + + + + + + + + + Binding to an organic cyclic compound, any molecular entity that contains carbon arranged in a cyclic molecular structure. + pr + 2011-09-23T02:31:01Z + molecular_function + GO:0097159 + organic cyclic compound binding + + + + + Binding to an organic cyclic compound, any molecular entity that contains carbon arranged in a cyclic molecular structure. + GOC:sjw + PMID:7583672 + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways involving the ammonium ion. + pr + 2011-09-28T04:21:30Z + ammonium ion metabolism + biological_process + ammonium metabolic process + GO:0097164 + ammonium ion metabolic process + + + + + The chemical reactions and pathways involving the ammonium ion. + GOC:dhl + GOC:tb + PMID:14671018 + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the formation of tooth enamel, occurring in two stages: secretory stage and maturation stage. + pr + 2011-11-21T09:01:24Z + enamel development + biological_process + GO:0097186 + amelogenesis + + + + + The process whose specific outcome is the formation of tooth enamel, occurring in two stages: secretory stage and maturation stage. + GOC:cjm + GOC:sl + PMID:10206335 + PMID:21196346 + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the formation of dentin, the mineralized tissue that constitutes the major bulk of teeth. Dentin may be one of three types: primary dentin, secondary dentin, and tertiary dentin. + pr + 2011-11-21T09:04:17Z + dentin development + dentine development + biological_process + GO:0097187 + dentinogenesis + + + + + The process whose specific outcome is the formation of dentin, the mineralized tissue that constitutes the major bulk of teeth. Dentin may be one of three types: primary dentin, secondary dentin, and tertiary dentin. + GOC:cjm + GOC:sl + PMID:10206335 + PMID:21196346 + + + + + + + + + A renal system process in which fluid circulating through the body is filtered through a barrier system. + pr + 2012-01-03T03:10:17Z + biological_process + GO:0097205 + renal filtration + + + + + A renal system process in which fluid circulating through the body is filtered through a barrier system. + GOC:pr + GOC:sart + + + + + + + + + + + + + + + + + + + Any biological process involved in the maintenance of an internal steady state of ammonium. + pr + 2012-03-22T02:51:22Z + ammonia homeostasis + biological_process + GO:0097272 + ammonium homeostasis + + + + + Any biological process involved in the maintenance of an internal steady state of ammonium. + GOC:yaf + PMID:12695560 + + + + + + + + + + + + + + + + + + + + Any biological process involved in the maintenance of an internal steady state of ammonium at the level of the cell. + pr + 2012-03-22T02:54:38Z + cellular ammonia homeostasis + biological_process + GO:0097275 + cellular ammonium homeostasis + + + + + Any biological process involved in the maintenance of an internal steady state of ammonium at the level of the cell. + GOC:yaf + PMID:12695560 + + + + + + + + + + + + + + + + + + + + The orderly movement of melanocytes from one site to another, often during the development of a multicellular organism. A melanocyte is a pigment cell derived from the neural crest. It contains melanin-filled pigment granules, which give a brown to black appearance. + pr + 2012-06-08T10:08:18Z + biological_process + GO:0097324 + melanocyte migration + + + + + The orderly movement of melanocytes from one site to another, often during the development of a multicellular organism. A melanocyte is a pigment cell derived from the neural crest. It contains melanin-filled pigment granules, which give a brown to black appearance. + CL:0000148 + GOC:uh + PMID:22637532 + + + + + + + + + + + + + + + + + + + + Binding to a carbohydrate derivative. + pr + 2012-08-02T13:03:39Z + molecular_function + GO:0097367 + + + carbohydrate derivative binding + + + + + Binding to a carbohydrate derivative. + GOC:pr + + + + + + + + + + + + + + + + + + + A prolongation or process extending from a glial cell. + pr + 2012-10-22T13:55:54Z + cellular_component + glial process + glial projection + GO:0097386 + glial cell projection + + + + + A prolongation or process extending from a glial cell. + GOC:mc + + + + + + + + + + + + + + + + + + + + The orderly movement of a neuroblast from one site to another, often during the development of a multicellular organism or multicellular structure. A neuroblast is any cell that will divide and give rise to a neuron. + pr + 2012-10-29T08:24:37Z + biological_process + GO:0097402 + neuroblast migration + + + + + The orderly movement of a neuroblast from one site to another, often during the development of a multicellular organism or multicellular structure. A neuroblast is any cell that will divide and give rise to a neuron. + CL:0000031 + GOC:jc + PMID:15543145 + + + + + + + + + + + + + + + + + + + + + An arrangement of closely apposed microtubules running parallel to each other. + pr + 2012-11-07T15:01:27Z + NIF_Subcellular:sao1872343973 + microtubule fascicle + cellular_component + GO:0097427 + microtubule bundle + + + + + An arrangement of closely apposed microtubules running parallel to each other. + NIF_Subcellular:sao1872343973 + + + + + + + + + + + + + + + + + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a supramolecular fiber, a polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure. + pr + 2012-11-27T15:46:25Z + GO:0043206 + extracellular fibril organisation + extracellular fibril organization + extracellular fibril organization and biogenesis + biological_process + fibril organisation + fibril organization + GO:0097435 + supramolecular fiber organization + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a supramolecular fiber, a polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure. + GOC:pr + + + + + extracellular fibril organization and biogenesis + GOC:mah + + + + + + + + + + + + + + + + + + + + + The entire complement of dendrites for a neuron, consisting of each primary dendrite and all its branches. + pr + 2012-12-17T12:31:49Z + NIF_Subcellular:sao172297168 + cellular_component + GO:0097447 + dendritic tree + + + + + The entire complement of dendrites for a neuron, consisting of each primary dendrite and all its branches. + GOC:aruk + GOC:bc + NIF_Subcellular:sao172297168 + + + + + + + + + + + + + + + + + + + + A prolongation or process extending from the soma of an astrocyte and wrapping around neurons. + pr + 2012-12-17T13:29:55Z + NIF_Subcellular:sao1630537580 + astrocyte process + cellular_component + peripheral astrocyte process + vellous process + GO:0097449 + astrocyte projection + + + + + A prolongation or process extending from the soma of an astrocyte and wrapping around neurons. + NIF_Subcellular:sao1630537580 + + + + + peripheral astrocyte process + NIF_Subcellular:sao1573004591 + PMID:12445894 + + + + + vellous process + NIF_Subcellular:sao1189060993 + + + + + + + + + Terminal process of astrocyte abutting non-neuronal surfaces in the brain. + pr + 2012-12-17T13:33:55Z + NIF_Subcellular:sao388182739 + astrocyte endfoot + cellular_component + GO:0097450 + astrocyte end-foot + + + + + Terminal process of astrocyte abutting non-neuronal surfaces in the brain. + NIF_Subcellular:sao388182739 + + + + + + + + + + + + + + + + + + + + Small finger-like extension of a Schwann cell that contacts the nodal membrane. + pr + 2012-12-19T13:01:02Z + NIF_Subcellular:sao1890444066 + cellular_component + GO:0097454 + Schwann cell microvillus + + + + + Small finger-like extension of a Schwann cell that contacts the nodal membrane. + NIF_Subcellular:sao1890444066 + PMID:15988042 + + + + + + + + + + + + + + + Axon of dentate gyrus granule cell projecting to hippocampal area CA3, characterized by expansions (mossy fiber expansions) giving the fibers a mossy appearance. These unmyelinated axons were first described by Ramon y Cajal. + pr + 2012-12-19T16:51:57Z + NIF_Subcellular:nlx_subcell_100312 + cellular_component + GO:0097457 + hippocampal mossy fiber + + + + + Axon of dentate gyrus granule cell projecting to hippocampal area CA3, characterized by expansions (mossy fiber expansions) giving the fibers a mossy appearance. These unmyelinated axons were first described by Ramon y Cajal. + NIF_Subcellular:nlx_subcell_100312 + PMID:17765709 + + + + + + + + + + + + + + + + + + + + The orderly movement of a motor neuron from one site to another. A motor neuron is an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement. + pr + 2013-04-23T13:00:46Z + biological_process + GO:0097475 + motor neuron migration + + + + + The orderly movement of a motor neuron from one site to another. A motor neuron is an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement. + CL:0000100 + GOC:yaf + PMID:20711475 + + + + + + + + + + + + + + + + + + + + A process in which a protein is transported to, or maintained in, a location within a non-motile cilium. + pr + 2013-08-13T12:16:26Z + biological_process + protein localization to nonmotile primary cilium + GO:0097499 + protein localization to non-motile cilium + + + + + A process in which a protein is transported to, or maintained in, a location within a non-motile cilium. + GOC:cilia + GOC:kmv + PMID:23128241 + + + + + + + + + + + + + + + + + + + A branched cellular projection (or cytoplasmic extension) that is extended from the surface of a dendritic immune cell, and which enables the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells. + pr + 2013-10-16T13:02:25Z + cellular_component + GO:0097511 + dendritic cell dendrite + + + + + A branched cellular projection (or cytoplasmic extension) that is extended from the surface of a dendritic immune cell, and which enables the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells. + CL:0000451 + GOC:BHF + GOC:cjm + PMID:12200351 + + + + + + + + + + + + + + + + + + + + A cardiac myofibril is a myofibril specific to cardiac muscle cells. + pr + 2013-10-16T13:04:58Z + cellular_component + GO:0097512 + cardiac myofibril + + + + + A cardiac myofibril is a myofibril specific to cardiac muscle cells. + GOC:cjm + GOC:devbiol + + + + + + + + + + + + + + + + + + + + A plasma membrane that is part of a sperm cell. + pr + 2013-10-18T11:31:17Z + cellular_component + GO:0097524 + sperm plasma membrane + + + + + A plasma membrane that is part of a sperm cell. + GOC:cjm + + + + + + + + + + + + + + + + + + + + The movement of a myeloid leukocyte within or between different tissues and organs of the body. + pr + 2013-11-11T13:59:43Z + biological_process + GO:0097529 + myeloid leukocyte migration + + + + + The movement of a myeloid leukocyte within or between different tissues and organs of the body. + GOC:cvs + PMID:22342843 + PMID:24157461 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the thymus epithelium is generated and organized. + pr + 2013-11-28T10:51:03Z + thymic epithelium morphogenesis + biological_process + GO:0097536 + thymus epithelium morphogenesis + + + + + The process in which the thymus epithelium is generated and organized. + GOC:pr + PMID:22342843 + + + + + + + + + + + + + + + + + + + + Merging of two or more vacuoles, or of vacuoles and vesicles within a cell to form a single larger vacuole. + pr + 2014-02-28T09:49:31Z + biological_process + GO:0097576 + vacuole fusion + + + + + Merging of two or more vacuoles, or of vacuoles and vesicles within a cell to form a single larger vacuole. + GOC:pr + GOC:vw + Wikipedia:Vacuole + + + + + + + + + Combining with any member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)) to initiate a change in cell activity. + pr + 2014-09-08T15:32:19Z + molecular_function + GO:0097642 + calcitonin family receptor activity + + + + + Combining with any member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)) to initiate a change in cell activity. + GOC:bhm + InterPro:IPR003287 + PMID:10871296 + PMID:12037140 + PMID:18687416 + + + + + + + + + Binding to a member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)). + pr + 2014-09-08T20:50:52Z + molecular_function + GO:0097644 + calcitonin family binding + + + + + Binding to a member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)). + GOC:bhm + InterPro:IPR021116 + PMID:10871296 + PMID:12037140 + PMID:18687416 + + + + + + + + + + + + + + + A protein complex that contains G protein-coupled receptors. + pr + 2014-09-10T09:14:30Z + G-protein coupled receptor complex + cellular_component + GO:0097648 + G protein-coupled receptor complex + + + + + A protein complex that contains G protein-coupled receptors. + GOC:bhm + + + + + + + + + + + + + + + + + + + + + + + + + + Any vesicle that is part of the intracellular region. + pr + 2016-03-29T17:39:45Z + cellular_component + GO:0097708 + intracellular vesicle + + + + + Any vesicle that is part of the intracellular region. + GOC:vesicles + + + + + + + + + + + + + + + The docking of a cytosolic centriole/basal body to the plasma membrane via the ciliary transition fibers. In some species this may happen via an intermediate step, by first docking to the ciliary vesicle via the ciliary transition fibers. The basal body-ciliary vesicle then relocates to the plasma membrane, followed by the ciliary vesicle fusing with the plasma membrane, effectively attaching the basal body to the plasma membrane. + pr + 2016-08-05T16:12:33Z + Reactome:R-HSA-5620912.1 + ciliary basal body docking + biological_process + anchoring of the basal body to the plasma membrane + GO:0097711 + Basal bodies in jawed vertebrates appear to first attach to a ciliary vesicle. It is unclear how specific this is to jawed vertebrates or if other organisms also employ this sequence. Some species like Giardia intestinalis do not relocate their basal bodies to the plasma membrane, but have their axonemes extend through the cytosol to then protrude out of the cell to form flagella. + ciliary basal body-plasma membrane docking + + + + + The docking of a cytosolic centriole/basal body to the plasma membrane via the ciliary transition fibers. In some species this may happen via an intermediate step, by first docking to the ciliary vesicle via the ciliary transition fibers. The basal body-ciliary vesicle then relocates to the plasma membrane, followed by the ciliary vesicle fusing with the plasma membrane, effectively attaching the basal body to the plasma membrane. + GOC:cilia + PMID:13978319 + PMID:23348840 + PMID:23530209 + PMID:25686250 + PMID:26981235 + Reactome:R-HSA-5620912.1 + + + + + + + + + + + + + + + The process in which vesicles formed at the trans-Golgi network are directed to the plasma membrane surrounding the base of the cilium, including the ciliary pocket, mediated by molecules at the vesicle membrane and target membrane surfaces. + pr + 2016-08-05T16:16:28Z + biological_process + GO:0097712 + vesicle targeting, trans-Golgi to periciliary membrane compartment + + + + + The process in which vesicles formed at the trans-Golgi network are directed to the plasma membrane surrounding the base of the cilium, including the ciliary pocket, mediated by molecules at the vesicle membrane and target membrane surfaces. + GOC:cilia + PMID:20106869 + PMID:23351793 + PMID:24814148 + PMID:26485645 + Reactome:R-HSA-5620920.1 + + + + + + + + + + + + + + + + + + + + The regrowth of neural tissue following its loss or destruction. + pr + 2016-08-25T13:14:27Z + biological_process + neuroregeneration + GO:0097719 + neural tissue regeneration + + + + + The regrowth of neural tissue following its loss or destruction. + Wikipedia:Neuroregeneration + + + + + + + + + + + + + + + + + + + + + Any process involved in the controlled movement of a sperm cell. + pr + 2016-09-01T12:00:45Z + sperm movement + biological_process + GO:0097722 + + sperm motility + + + + + Any process involved in the controlled movement of a sperm cell. + GOC:cilia + GOC:krc + + + + + + + + + A cilium which may have a variable array of axonemal microtubules but does not contain molecular motors. + pr + 2016-09-29T14:02:11Z + GO:0031513 + immotile cilium + nonmotile cilium + cellular_component + immotile primary cilium + nonmotile primary cilia + nonmotile primary cilium + sensory cilium + GO:0097730 + non-motile cilium + + + + + A cilium which may have a variable array of axonemal microtubules but does not contain molecular motors. + GOC:cilia + GOC:dgh + GOC:kmv + PMID:17009929 + PMID:20144998 + PMID:22118931 + + + + + + + + + A non-motile cilium where the axoneme has a ring of nine outer microtubule doublets but no central microtubules (and is therefore called a 9+0 axoneme). + pr + 2016-09-29T14:05:03Z + 9+0 immotile cilium + non-motile 9+0 cilium + primary cilium + cellular_component + GO:0097731 + This type of cilia may be present in solitary (authentic primary cilia in many cell types) or in multiple copies (e.g. in Grueneberg ganglion neurons). + 9+0 non-motile cilium + + + + + A non-motile cilium where the axoneme has a ring of nine outer microtubule doublets but no central microtubules (and is therefore called a 9+0 axoneme). + GOC:cilia + PMID:22118931 + + + + + + + + + + + + + + + + + + + + + A specialised 9+0 non-motile cilium found in photoreceptor cells. A ciliary transition zone called 'photoreceptor connecting cilium' links the photoreceptor outer segment to the inner segment. + pr + 2016-09-30T10:50:11Z + photoreceptor cilium + cellular_component + GO:0097733 + photoreceptor cell cilium + + + + + A specialised 9+0 non-motile cilium found in photoreceptor cells. A ciliary transition zone called 'photoreceptor connecting cilium' links the photoreceptor outer segment to the inner segment. + GOC:cilia + Wikipedia:Photoreceptor_cell#Histology + + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle fiber cell. Skeletal muscle fiber differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual skeletal muscle fibers fuse to form bigger myotubes and start to contract. + dos + 2013-10-15T14:00:34Z + biological_process + GO:0098528 + skeletal muscle fiber differentiation + + + + + The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle fiber cell. Skeletal muscle fiber differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual skeletal muscle fibers fuse to form bigger myotubes and start to contract. + GOC:dos + + + + + + + + + + + + + + + + + + + + Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism. + https://github.com/geneontology/go-ontology/issues/22173 + dos + 2013-11-11T12:59:11Z + GO:0009814 + defence response incompatible interaction + defence response to pathogen, incompatible interaction + defense response, incompatible interaction + resistance response to pathogen + biological_process + GO:0098542 + + + defense response to other organism + + + + + Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism. + GOC:dos + + + + + + + + + + A vocalization behavior that is the result of learning. + dos + 2014-01-24T12:48:57Z + biological_process + GO:0098583 + Examples include human speech and learned bird song. + learned vocalization behavior + + + + + A vocalization behavior that is the result of learning. + GOC:BHF + GOC:dos + GOC:rl + PMID:16418265 + PMID:17035521 + + + + + + + + + + + + + + + + + + + + The lipid bilayer that forms the outer-most layer of an organelle. + dos + 2014-02-26T13:41:31Z + cellular_component + GO:0098588 + Examples include the outer membranes of double membrane bound organelles such as mitochondria as well as the bounding membranes of single-membrane bound organelles such as lysosomes. + bounding membrane of organelle + + + + + The lipid bilayer that forms the outer-most layer of an organelle. + GOC:dos + + + + + + + + + + + + + + + + + + + A membrane that is a (regional) part of the plasma membrane. + dos + 2014-03-06T11:55:32Z + region of plasma membrane + cellular_component + GO:0098590 + + Note that this term should not be used for direct manual annotation as it should always be possible to choose a more specific subclass. + plasma membrane region + + + + + A membrane that is a (regional) part of the plasma membrane. + GOC:dos + + + + + + + + + Vocalisation behavior that is the result of learning, or the process by which new vocalizations are learned. + dos + 2014-04-10T11:34:33Z + biological_process + GO:0098598 + This grouping term is necessary because, in the absence of conditional mutations, it is not possible to use phenotypic evidence to distinguish an effect on vocal learning from an effect on learned vocalisation behavior. + learned vocalization behavior or vocal learning + + + + + Vocalisation behavior that is the result of learning, or the process by which new vocalizations are learned. + GOC:BHF + GOC:dos + GOC:rl + PMID:16418265 + PMID:17035521 + + + + + + + + + The attachment of one cell to another cell via adhesion molecules. + dos + 2014-04-16T13:40:03Z + GO:0016337 + biological_process + single organismal cell-cell adhesion + GO:0098609 + cell-cell adhesion + + + + + The attachment of one cell to another cell via adhesion molecules. + GOC:dos + + + + + + + + + + + + + + + + + + + + The binding by a cell-adhesion protein on a cell surface to an adhesion molecule on another cell surface or an external substrate, to mediate adhesion of the cell to the external substrate or to another cell. + https://github.com/geneontology/go-ontology/issues/22959 + cell adhesion molecule + protein binding involved in cell adhesion + molecular_function + GO:0098631 + + + cell adhesion mediator activity + + + + + The binding by a cell-adhesion protein on a cell surface to an adhesion molecule on another cell surface or an external substrate, to mediate adhesion of the cell to the external substrate or to another cell. + GOC:vw + Wikipedia:Cell_adhesion + + + + + + + + + + + + + + + + + + + + The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to another cell. + cell-cell adhesion molecule + protein binding involved in cell-cell adhesion + molecular_function + GO:0098632 + cell-cell adhesion mediator activity + + + + + The binding by a cell-adhesion protein on the cell surface to an extracellular matrix component, to mediate adhesion of the cell to another cell. + Wikipedia:Cell_adhesion + + + + + + + + + + + + + + + + + + + + Binding to a collagen fibril. + molecular_function + GO:0098633 + collagen fibril binding + + + + + Binding to a collagen fibril. + GOC:dos + PMID:21421911 + + + + + + + + + + + + + + + + + + + Any protein complex that is capable of carrying out some part of the process of cell-cell adhesion. + cellular_component + GO:0098635 + protein complex involved in cell-cell adhesion + + + + + Any protein complex that is capable of carrying out some part of the process of cell-cell adhesion. + GOC:dos + + + + + + + + + + + + + + + + + + + Any protein complex that is capable of carrying out some part of the process of cell adhesion to the cell matrix or to another cell. + GO:1990307 + cellular_component + cell adhesion complex + GO:0098636 + protein complex involved in cell adhesion + + + + + Any protein complex that is capable of carrying out some part of the process of cell adhesion to the cell matrix or to another cell. + GOC:dos + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A collagen trimer that forms networks. + cellular_component + GO:0098642 + network-forming collagen trimer + + + + + A collagen trimer that forms networks. + PMID:21421911 + + + + + + + + + + + + + + + + + + + + + A supramolecular assembly of fibrillar collagen complexes in the form of a long fiber (fibril) with transverse striations (bands). + cellular_component + GO:0098643 + banded collagen fibril + + + + + A supramolecular assembly of fibrillar collagen complexes in the form of a long fiber (fibril) with transverse striations (bands). + GOC:dos + PMID:21421911 + + + + + + + + + + + + + + + + + + + + + A complex of collagen trimers such as a fibril or collagen network. + Supramolecular aggregate of collagen + Supramolecular collagen assembly + cellular_component + GO:0098644 + complex of collagen trimers + + + + + A complex of collagen trimers such as a fibril or collagen network. + GOC:dos + + + + + Supramolecular aggregate of collagen + PMID:19693541 + + + + + Supramolecular collagen assembly + PMID:21421911 + + + + + + + + + + + + + + + A supramolecular complex that consists of collagen triple helices associated to form a network. + cellular_component + GO:0098645 + collagen network + + + + + A supramolecular complex that consists of collagen triple helices associated to form a network. + GOC:dos + PMID:21421911 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Any collagen timer that is part of a basement membrane. + cellular_component + GO:0098651 + basement membrane collagen trimer + + + + + Any collagen timer that is part of a basement membrane. + GOC:dos + PMID:21421911 + + + + + + + + + + + + + + + + + + + + + + + + + + + The directed movement of some substance from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis. + uptake + biological_process + GO:0098657 + import into cell + + + + + The directed movement of some substance from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis. + GOC:dos + + + + + + + + + + + + + + + + + + + The series of molecular signals generated as a consequence of a G protein-coupled serotonin receptor binding to one of its physiological ligands. + dos + 2016-12-21T12:07:58Z + G-protein coupled serotonin receptor signaling pathway + biological_process + GO:0098664 + G protein-coupled serotonin receptor signaling pathway + + + + + The series of molecular signals generated as a consequence of a G protein-coupled serotonin receptor binding to one of its physiological ligands. + GOC:mah + + + + + + + + + + + + + + + + + + + A protein complex that is capable of serotonin receptor activity. + dos + 2016-12-21T12:24:56Z + 5-HT receptor complex + 5-hydroxytryptamine receptor complex + 5HT receptor complex + cellular_component + GO:0098665 + serotonin receptor complex + + + + + A protein complex that is capable of serotonin receptor activity. + GOC:TermGenie + GOC:bhm + GO_REF:0000088 + PMID:16116092 + + + + + + + + + + + + + + + + + + + + + + + + + A protein complex that is capable of G protein-coupled serotonin receptor activity. + https://github.com/geneontology/go-ontology/issues/12942 + dos + 2016-12-21T12:28:12Z + G-protein coupled serotonin receptor complex + cellular_component + GO:0098666 + G protein-coupled serotonin receptor complex + + + + + A protein complex that is capable of G protein-coupled serotonin receptor activity. + GOC:TermGenie + GOC:bhm + GO_REF:0000088 + + + + + + + + + + + + + + + + + + + Division of a stem cell during which it retains its identity and buds off a daughter cell with a new identity. + biological_process + GO:0098722 + asymmetric stem cell division + + + + + Division of a stem cell during which it retains its identity and buds off a daughter cell with a new identity. + GOC:dos + PMID:18513950 + + + + + + + + + + + + + + + + + + + + A myofibril of a skeletal muscle fiber. + cellular_component + GO:0098723 + skeletal muscle myofibril + + + + + A myofibril of a skeletal muscle fiber. + GOC:dos + + + + + + + + + + + + + + + + + + + + Any process involved in the maintenance of an internal steady state of inorganic ions within an organism or cell. + biological_process + GO:0098771 + inorganic ion homeostasis + + + + + Any process involved in the maintenance of an internal steady state of inorganic ions within an organism or cell. + GOC:dos + + + + + + + + + + + + + + + A molecular function regulator regulates the activity of its target via non-covalent binding that does not result in covalent modification to the target. Examples of molecular function regulators include regulatory subunits of multimeric enzymes and channels. Mechanisms of regulation include allosteric changes in the target and competitive inhibition. + https://github.com/geneontology/go-ontology/issues/20854 + https://github.com/geneontology/go-ontology/issues/20862 + molecular function regulator + molecular_function + GO:0098772 + + + + + molecular function regulator activity + + + + + A molecular function regulator regulates the activity of its target via non-covalent binding that does not result in covalent modification to the target. Examples of molecular function regulators include regulatory subunits of multimeric enzymes and channels. Mechanisms of regulation include allosteric changes in the target and competitive inhibition. + GOC:dos + GOC:pt + + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of the skin epidermis over time, from its formation to the mature structure. + biological_process + GO:0098773 + skin epidermis development + + + + + The process whose specific outcome is the progression of the skin epidermis over time, from its formation to the mature structure. + GOC:dos + + + + + + + + + + + + + + + + + + + + + + + + + + Any protein complex that is part of a membrane. + cellular_component + GO:0098796 + + membrane protein complex + + + + + Any protein complex that is part of a membrane. + GOC:dos + + + + + + + + + + + + + + + + + + + + + + + + + + Any protein complex that is part of the plasma membrane. + cellular_component + GO:0098797 + plasma membrane protein complex + + + + + Any protein complex that is part of the plasma membrane. + GOC:dos + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by the renal system. + biological_process + GO:0098801 + regulation of renal system process + + + + + Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by the renal system. + GOC:dos + + + + + + + + + + + + + + + + + + + + + + + Any protein complex that is part of the plasma membrane and which functions as a signaling receptor. + cellular_component + GO:0098802 + + Note that this term is in the subset of terms that should not be used for direct gene product annotation. Instead, select a child term or, if no appropriate child term exists, please request a new term. Direct annotations to this term may be amended during annotation QC. + plasma membrane signaling receptor complex + + + + + Any protein complex that is part of the plasma membrane and which functions as a signaling receptor. + GOC:dos + + + + + + + + + + + + + + + + + + + The portion of the plasma membrane surrounding a non-motile cilium. + cellular_component + nonmotile primary cilium membrane + GO:0098804 + non-motile cilium membrane + + + + + The portion of the plasma membrane surrounding a non-motile cilium. + GOC:cilia + GOC:dos + + + + + + + + + + + + + + + + + + + + + + + The directed movement of a protein along a microtubule, mediated by motor proteins. + microtubule-based protein transport + biological_process + GO:0098840 + protein transport along microtubule + + + + + The directed movement of a protein along a microtubule, mediated by motor proteins. + PMID:25987607 + + + + + + + + + + + + + + + A cell projection of a podocyte (glomerular visceral epithelial cell) forming a foot-like structure projecting from a podocyte primary projection, that wraps around capillaries of a renal glomerulus. Adjacent feet (pedicels) interdigitate, leaving thin filtration slits between them, which are covered by slit diaphragms. + Wikipedia:Podocyte + pedicel + podocyte foot process + secondary podocyte projection + cellular_component + GO:0098846 + podocyte foot + + + + + A cell projection of a podocyte (glomerular visceral epithelial cell) forming a foot-like structure projecting from a podocyte primary projection, that wraps around capillaries of a renal glomerulus. Adjacent feet (pedicels) interdigitate, leaving thin filtration slits between them, which are covered by slit diaphragms. + PMID:25324828 + + + + + pedicel + Wikipedia:Podocyte + + + + + podocyte foot process + PMID:25324828 + + + + + + + + + + + + + + + A cell projection supported by an assembly of actin filaments, and which lacks microtubules. + cellular_component + GO:0098858 + actin-based cell projection + + + + + A cell projection supported by an assembly of actin filaments, and which lacks microtubules. + PMID:15661519 + + + + + + + + + + + + + + + + + + + The increase in size or mass of an intramembranous bone that contributes to the shaping of the bone. + biological_process + GO:0098867 + intramembranous bone growth + + + + + The increase in size or mass of an intramembranous bone that contributes to the shaping of the bone. + PMID:26399686 + + + + + + + + + + + + + + + + + + + + + + + + + The increase in size or mass of a bone that contributes to the shaping of that bone. + biological_process + GO:0098868 + bone growth + + + + + The increase in size or mass of a bone that contributes to the shaping of that bone. + GOC:dos + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The directed movement of substances to the plasma membrane in transport vesicles that fuse with the plasma membrane by exocytosis. + biological_process + GO:0098876 + vesicle-mediated transport to the plasma membrane + + + + + The directed movement of substances to the plasma membrane in transport vesicles that fuse with the plasma membrane by exocytosis. + GOC:dos + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The directed movement of neurotransmitter receptor to the plasma membrane in transport vesicles. + biological_process + GO:0098877 + + neurotransmitter receptor transport to plasma membrane + + + + + The directed movement of neurotransmitter receptor to the plasma membrane in transport vesicles. + GOC:dos + + + + + + + + + + + + + + + + + + + + + + + + + Any protein complex that is capable of functioning as a neurotransmitter receptor. + cellular_component + GO:0098878 + neurotransmitter receptor complex + + + + + Any protein complex that is capable of functioning as a neurotransmitter receptor. + GOC:dos + + + + + + + + + + + + + + + + + + + + + + + The directed movement of organelles or molecules along microtubules in axons. + Wikipedia:Axoplasmic_transport + axon cargo transport + axoplasmic transport + biological_process + GO:0098930 + + axonal transport + + + + + The directed movement of organelles or molecules along microtubules in axons. + ISBN:0815316194 + + + + + + + + + + + + + + + + + + + + + + + The directed movement of organelles or molecules along microtubules in dendrites. + dendrite cargo transport + biological_process + GO:0098935 + + dendritic transport + + + + + The directed movement of organelles or molecules along microtubules in dendrites. + ISBN:0815316194 + + + + + + + + + + + + + + + + + + + + Combining with glutamate and transmitting a signal from one side of the membrane to the other by activating an associated G-protein, initiating a change in cell activity. + G-protein coupled glutamate receptor activity + molecular_function + GO:0098988 + G protein-coupled glutamate receptor activity + + + + + Combining with glutamate and transmitting a signal from one side of the membrane to the other by activating an associated G-protein, initiating a change in cell activity. + GOC:dos + + + + + + + + + A cellular component that consists of an indeterminate number of proteins or macromolecular complexes, organized into a regular, higher-order structure such as a polymer, sheet, network or a fiber. + cellular_component + GO:0099080 + supramolecular complex + + + + + A cellular component that consists of an indeterminate number of proteins or macromolecular complexes, organized into a regular, higher-order structure such as a polymer, sheet, network or a fiber. + GOC:dos + + + + + + + + + + + + + + + + + + + + A polymeric supramolecular structure. + cellular_component + GO:0099081 + supramolecular polymer + + + + + A polymeric supramolecular structure. + GOC:dos + + + + + + + + + + + + + + + + + + + The movement of a cellular component as a result of microtubule polymerization. + biological_process + GO:0099098 + microtubule polymerization based movement + + + + + The movement of a cellular component as a result of microtubule polymerization. + GOC:cjm + ISBN:0815316194 + + + + + + + + + + + + + + + + + + + A microtubule-based process that results in the transport of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules. + biological_process + GO:0099111 + microtubule-based transport + + + + + A microtubule-based process that results in the transport of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules. + GOC:cjm + ISBN:0815316194 + + + + + + + + + + + + + + + + + + + + + + + + + + + The transport of a protein driven by polymerization of a microtubule to which it is attached. + biological_process + GO:0099112 + microtubule polymerization based protein transport + + + + + The transport of a protein driven by polymerization of a microtubule to which it is attached. + GOC:dos + GOC:vw + PMID:11018050 + + + + + + + + + + + + + + + + + + + + + + + A microtubule-based process that results in the transport of proteins. + biological_process + GO:0099118 + microtubule-based protein transport + + + + + A microtubule-based process that results in the transport of proteins. + GOC:vw + + + + + + + + + + + + + + + + + + + The regulated release of dopamine from the somatodendritic compartment (cell body or dendrites) of a neuron. + STD DA release + STD dopamine release + somatodendritic dopamine release + biological_process + GO:0099123 + somato-dendritic dopamine secretion + + + + + The regulated release of dopamine from the somatodendritic compartment (cell body or dendrites) of a neuron. + GOC:PARL + GOC:bf + PMID:21576241 + + + + + STD DA release + PMID:21576241 + + + + + STD dopamine release + PMID:21576241 + + + + + somatodendritic dopamine release + PMID:21576241 + + + + + + + + + + + + + + + + + + + The regulated release of dopamine from an axon. + axonal DA release + axonal dopamine release + biological_process + GO:0099124 + axonal dopamine secretion + + + + + The regulated release of dopamine from an axon. + GOC:PARL + GOC:bf + PMID:21576241 + + + + + axonal DA release + PMID:21576241 + + + + + axonal dopamine release + PMID:21576241 + + + + + + + + + + + + + + + + + + + + + + + + + + + Fusion of the membrane of a vesicle with the plasma membrane, thereby releasing its contents into the extracellular space. + biological_process + GO:0099500 + vesicle fusion to plasma membrane + + + + + Fusion of the membrane of a vesicle with the plasma membrane, thereby releasing its contents into the extracellular space. + GOC:aruk + GOC:bc + ISBN:0071120009 + PMID:18618940 + + + + + + + + + + + + + + + + + + + + The lipid bilayer surrounding an exocytic vesicle. + secretory vesicle membrane + cellular_component + GO:0099501 + exocytic vesicle membrane + + + + + The lipid bilayer surrounding an exocytic vesicle. + GOC:dos + + + + + + + + + + + + + + + + + + + + A cytoplasmic, membrane bound vesicle that is capable of fusing to the plasma membrane to release its contents into the extracellular space. + cellular_component + GO:0099503 + + secretory vesicle + + + + + A cytoplasmic, membrane bound vesicle that is capable of fusing to the plasma membrane to release its contents into the extracellular space. + GOC:dos + + + + + + + + + + + + + + + + + + + + + + + + A polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure. + GO:0043205 + cellular_component + fibril + GO:0099512 + supramolecular fiber + + + + + A polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure. + GOC:dos + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A component of the cytoskeleton consisting of a homo or heteropolymeric fiber constructed from an indeterminate number of protein subunits. + cellular_component + GO:0099513 + polymeric cytoskeletal fiber + + + + + A component of the cytoskeleton consisting of a homo or heteropolymeric fiber constructed from an indeterminate number of protein subunits. + GOC:dos + + + + + + + + + + + + + + + + + + + The transport of organelles or other particles from one location in the cell to another along actin filaments. + tb + 2009-05-27T10:56:08Z + biological_process + GO:0099515 + actin filament-based transport + + + + + The transport of organelles or other particles from one location in the cell to another along actin filaments. + GOC:dos + GOC:dph + GOC:mah + GOC:tb + + + + + + + + + + + + + + + + + + + + + + + The directed movement of a vesicle along a cytoskeletal fiber such as a microtubule or and actin filament, mediated by motor proteins. + cytoskeletal fiber-based vesicle localization + vesicle cytoskeletal transport + biological_process + GO:0099518 + vesicle cytoskeletal trafficking + + + + + The directed movement of a vesicle along a cytoskeletal fiber such as a microtubule or and actin filament, mediated by motor proteins. + GOC:ecd + GOC:rl + + + + + cytoskeletal fiber-based vesicle localization + GOC:rl + + + + + + + + + + + + + + + + + + + + + + + + + + + Combining with a neurotransmitter and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. + G-protein coupled neurotransmitter receptor activity + molecular_function + GO:0099528 + G protein-coupled neurotransmitter receptor activity + + + + + Combining with a neurotransmitter and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. + GOC:bf + GOC:fj + GOC:mah + + + + + + + + + + + + + + + + + + + + Any (proper) part of the cytoplasm of a single cell of sufficient size to still be considered cytoplasm. + cellular_component + GO:0099568 + + cytoplasmic region + + + + + Any (proper) part of the cytoplasm of a single cell of sufficient size to still be considered cytoplasm. + GOC:dos + + + + + + + + + + + + + + + + + + + + Combining with the biogenic amine serotonin and transmitting a signal across a membrane by activating some effector activity. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates. + molecular_function + GO:0099589 + serotonin receptor activity + + + + + Combining with the biogenic amine serotonin and transmitting a signal across a membrane by activating some effector activity. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates. + GOC:dos + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity. Modulation may be via an effect on ligand affinity, or effector funtion such as ion selectivity or pore opening/closing in ionotropic receptors. + biological_process + GO:0099601 + + regulation of neurotransmitter receptor activity + + + + + Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity. Modulation may be via an effect on ligand affinity, or effector funtion such as ion selectivity or pore opening/closing in ionotropic receptors. + GOC:dos + + + + + + + + + + + + + + + + + + + A molecular function that directly (via physical interaction or direct modification) activates, inhibits or otherwise modulates the activity of a neurotransmitter receptor. Modulation of activity includes changes in desensitization rate, ligand affinity, ion selectivity and pore-opening/closing. + molecular_function + GO:0099602 + neurotransmitter receptor regulator activity + + + + + A molecular function that directly (via physical interaction or direct modification) activates, inhibits or otherwise modulates the activity of a neurotransmitter receptor. Modulation of activity includes changes in desensitization rate, ligand affinity, ion selectivity and pore-opening/closing. + GOC:dos + PMID:12740117 + PMID:18387948 + + + + + + + + + + + + + + + + + + + A process in which a protein is transported to or maintained in a location within an axon. + biological_process + GO:0099612 + protein localization to axon + + + + + A process in which a protein is transported to or maintained in a location within an axon. + GOC:dos + PMID:26157139 + + + + + + + + + + + + + + + + + + + + + + + A process in which protein is transported from one region of the plasma membrane to another. + biological_process + GO:0099632 + protein transport within plasma membrane + + + + + A process in which protein is transported from one region of the plasma membrane to another. + GOC:dos + + + + + + + + + + + + + + + + + + + + The directed movement of neurotransmitter receptors. + biological_process + GO:0099637 + + neurotransmitter receptor transport + + + + + The directed movement of neurotransmitter receptors. + GOC:dos + + + + + + + + + + + + + + + + + + + + + + + + + + + + The directed movement of proteins along microtubules in neuron projections. + axonal protein transport + biological_process + GO:0099640 + + axo-dendritic protein transport + + + + + The directed movement of proteins along microtubules in neuron projections. + ISBN:0815316194 + + + + + + + + + + + + + + + + + + + + The complete extent of cell cortex that underlies some some region of the plasma membrane. + perimembrane region + cellular_component + GO:0099738 + + cell cortex region + + + + + The complete extent of cell cortex that underlies some some region of the plasma membrane. + GOC:dos + + + + + + + + + + + + + + + + + + + Any protein phosphorylation process that negatively regulates protein kinase activity. + cjm + 2015-04-02T04:13:19Z + biological_process + GO:0100002 + negative regulation of protein kinase activity by protein phosphorylation + + + + + Any protein phosphorylation process that negatively regulates protein kinase activity. + GOC:cjm + GOC:obol + + + + + + + + + + + + + + + + + + + The multiplication or reproduction of blood vessel endothelial cells, resulting in the expansion of a cell population. + biological_process + GO:0101023 + vascular endothelial cell proliferation + + + + + The multiplication or reproduction of blood vessel endothelial cells, resulting in the expansion of a cell population. + GOC:BHF + GOC:BHF_telomere + GOC:nc + PMID:23201774 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which a nuclear membrane is synthesized, aggregates, and bonds together. + biological_process + GO:0101025 + nuclear membrane biogenesis + + + + + The process in which a nuclear membrane is synthesized, aggregates, and bonds together. + GOC:vw + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an environmental stimulus. + dos + 2017-02-17T16:02:42Z + biological_process + GO:0104004 + cellular response to environmental stimulus + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an environmental stimulus. + GOC:dos + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the inflammatory response to wounding. + hjd + 2017-04-28T20:03:14Z + biological_process + GO:0106014 + regulation of inflammatory response to wounding + + + + + Any process that modulates the frequency, rate or extent of the inflammatory response to wounding. + GOC:BHF + GOC:BHF_miRNA + GOC:rph + PMID:26022821 + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response to wounding. + hjd + 2017-04-28T20:09:46Z + biological_process + GO:0106015 + negative regulation of inflammatory response to wounding + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response to wounding. + GOC:BHF + GOC:BHF_miRNA + GOC:rph + PMID:26022821 + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the inflammatory response to wounding. + hjd + 2017-04-28T20:16:31Z + biological_process + GO:0106016 + positive regulation of inflammatory response to wounding + + + + + Any process that activates or increases the frequency, rate or extent of the inflammatory response to wounding. + GOC:BHF + GOC:BHF_miRNA + GOC:rph + PMID:26022821 + + + + + + + + + + + + + + + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a neuron, e.g. an axon, or a dendrite. + hjd + 2017-06-23T18:30:18Z + biological_process + GO:0106027 + neuron projection organization + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a neuron, e.g. an axon, or a dendrite. + GOC:aruk + GOC:bc + PMID:11585923 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of vesicle fusion with Golgi apparatus. + hjd + 2019-06-27T15:12:22Z + biological_process + GO:0106214 + regulation of vesicle fusion with Golgi apparatus + + + + + Any process that modulates the frequency, rate or extent of vesicle fusion with Golgi apparatus. + GOC:se + PMID:26195667 + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of vesicle fustion with Golgi apparatus. + hjd + 2019-06-27T15:17:17Z + biological_process + GO:0106215 + negative regulation of vesicle fusion with Golgi apparatus + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of vesicle fustion with Golgi apparatus. + GOC:se + PMID:26195667 + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of vesicle fusion with Golgi apparatus. + hjd + 2019-06-27T15:20:59Z + biological_process + GO:0106216 + positive regulation of vesicle fusion with Golgi apparatus + + + + + Any process that activates or increases the frequency, rate or extent of vesicle fusion with Golgi apparatus. + GOC:se + PMID:26195667 + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the assembly, disassembly or arrangement of constituent parts of the basement membrane. + kmv + biological_process + GO:0110011 + regulation of basement membrane organization + + + + + Any process that modulates the frequency, rate or extent of the assembly, disassembly or arrangement of constituent parts of the basement membrane. + GOC:ha + PMID:27404358 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin. + kmv + 2017-06-20T19:28:58Z + biological_process + GO:0110020 + regulation of actomyosin structure organization + + + + + Any process that modulates the frequency, rate or extent of the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin. + GOC:lf + PMID:22790195 + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of the pharynx are generated and organized. + kmv + 2017-07-24T20:51:28Z + biological_process + GO:0110040 + pharynx morphogenesis + + + + + The process in which the anatomical structures of the pharynx are generated and organized. + GOC:rz + PMID:20805556 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of pharynx morphogenesis, the process in which the anatomical structure of the pharynx is generated and organized. + kmv + 2017-07-24T21:00:20Z + biological_process + GO:0110041 + regulation of pharynx morphogenesis + + + + + Any process that modulates the frequency, rate or extent of pharynx morphogenesis, the process in which the anatomical structure of the pharynx is generated and organized. + GOC:rz + PMID:20805556 + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of pharynx morphogenesis. + kmv + 2017-07-24T21:05:08Z + biological_process + GO:0110042 + negative regulation of pharynx morphogenesis + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of pharynx morphogenesis. + GOC:rz + PMID:20805556 + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of pharynx morphogenesis. + kmv + 2017-07-24T21:09:48Z + biological_process + GO:0110043 + positive regulation of pharynx morphogenesis + + + + + Any process that activates or increases the frequency, rate or extent of pharynx morphogenesis. + GOC:rz + PMID:20805556 + + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of actin filament organization. + kmv + 2017-09-20T19:52:57Z + biological_process + GO:0110053 + regulation of actin filament organization + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate or extent of actin filament organization. + GOC:kmv + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of blood vessel endothelial cell differentiation. + kmv + 2017-10-23T14:32:09Z + biological_process + GO:0110057 + regulation of blood vessel endothelial cell differentiation + + + + + Any process that modulates the frequency, rate or extent of blood vessel endothelial cell differentiation. + GOC:BHF + GOC:BHF_miRNA + GOC:rph + PMID:23072816 + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of blood vessel endothelial cell differentiation. + kmv + 2017-10-23T14:38:19Z + biological_process + GO:0110058 + positive regulation of blood vessel endothelial cell differentiation + + + + + Any process that activates or increases the frequency, rate or extent of blood vessel endothelial cell differentiation. + GOC:BHF + GOC:BHF_miRNA + GOC:rph + PMID:23072816 + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel endothelial cell differentiation. + kmv + 2017-10-23T14:47:29Z + biological_process + GO:0110059 + negative regulation of blood vessel endothelial cell differentiation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel endothelial cell differentiation. + GOC:BHF + GOC:BHF_miRNA + GOC:rph + PMID:23072816 + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of placenta blood vessel development. + kmv + 2018-02-01T14:49:12Z + biological_process + GO:0110079 + regulation of placenta blood vessel development + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate or extent of placenta blood vessel development. + GOC:BHF + GOC:BHF_miRNA + GOC:rph + PMID:27748453 + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of placenta blood vessel development. + kmv + 2018-02-01T14:55:30Z + biological_process + GO:0110080 + positive regulation of placenta blood vessel development + + + + + Any process that activates or increases the frequency, rate or extent of placenta blood vessel development. + GOC:BHF + GOC:BHF_miRNA + GOC:rph + PMID:27748453 + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of placenta blood vessel development. + kmv + 2018-02-01T15:01:11Z + biological_process + GO:0110081 + negative regulation of placenta blood vessel development + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of placenta blood vessel development. + GOC:BHF + GOC:BHF_miRNA + GOC:rph + PMID:27748453 + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldehyde stimulus. + kmv + 2018-02-16T21:29:18Z + biological_process + GO:0110096 + cellular response to aldehyde + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldehyde stimulus. + GOC:vw + PMID:25656103 + + + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of animal organ morphogenesis. + kmv + 2018-07-05T14:10:14Z + biological_process + GO:0110110 + positive regulation of animal organ morphogenesis + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that activates or increases the frequency, rate or extent of animal organ morphogenesis. + GOC:kmv + + + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of animal organ morphogenesis. + kmv + 2018-07-05T14:25:21Z + biological_process + GO:0110111 + negative regulation of animal organ morphogenesis + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of animal organ morphogenesis. + GOC:kmv + + + + + + + + + + + + + + + + + + + The orderly movement of a myotube cell from one site to another, often during the development of a multicellular organism. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate, and fuse. + kmv + 2018-08-22T20:58:09Z + biological_process + GO:0110122 + myotube cell migration + + + + + The orderly movement of a myotube cell from one site to another, often during the development of a multicellular organism. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate, and fuse. + GOC:ha + PMID:29122742 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of myotube cell migration. + kmv + 2018-08-22T21:06:53Z + biological_process + GO:0110123 + regulation of myotube cell migration + + + + + Any process that modulates the frequency, rate or extent of myotube cell migration. + GOC:ha + PMID:29122742 + + + + + + + + + + + + + + + + + + + Any process that activates, maintains or increases the frequency, rate or extent of myotube cell migration. + kmv + 2018-08-22T21:09:38Z + biological_process + GO:0110124 + positive regulation of myotube cell migration + + + + + Any process that activates, maintains or increases the frequency, rate or extent of myotube cell migration. + GOC:ha + PMID:29122742 + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of myotube cell migration. + kmv + 2018-08-22T21:12:47Z + biological_process + GO:0110125 + negative regulation of myotube cell migration + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of myotube cell migration. + GOC:ha + PMID:29122742 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis, the process in which the anatomical structure of the imaginal disc-derived leg joint is generated and organized. + kmv + 2019-02-12T15:31:25Z + biological_process + GO:0110137 + regulation of imaginal disc-derived leg joint morphogenesis + + + + + Any process that modulates the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis, the process in which the anatomical structure of the imaginal disc-derived leg joint is generated and organized. + GOC:ha + PMID:25329825 + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis. + kmv + 2019-02-12T15:37:05Z + biological_process + GO:0110138 + positive regulation of imaginal disc-derived leg joint morphogenesis + + + + + Any process that activates or increases the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis. + GOC:ha + PMID:25329825 + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis. + kmv + 2019-02-12T15:40:09Z + biological_process + GO:0110139 + negative regulation of imaginal disc-derived leg joint morphogenesis + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc-derived leg joint morphogenesis. + GOC:ha + PMID:25329825 + + + + + + + + + The process where mineral crystals are formed and deposited in an organized fashion in a matrix (either cellular or extracellular) by living organisms. This gives rise to inorganic compound-based structures such as skeleton, teeth, ivory, shells, cuticle, and corals as well as bacterial biomineralization products. + kmv + 2019-06-10T17:55:28Z + Wikipedia:Biomineralization + biomineralisation + mineralisation + mineralization + biomineral formation + biological_process + GO:0110148 + biomineralization + + + + + The process where mineral crystals are formed and deposited in an organized fashion in a matrix (either cellular or extracellular) by living organisms. This gives rise to inorganic compound-based structures such as skeleton, teeth, ivory, shells, cuticle, and corals as well as bacterial biomineralization products. + GOC:aa + PMID:24395694 + PMID:28229486 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of biomineralization, the formation and deposition of mineral crystals by living organisms. + kmv + 2019-06-10T18:06:59Z + regulation of biomineralisation + regulation of mineralisation + regulation of mineralization + regulation of biomineral formation + biological_process + GO:0110149 + regulation of biomineralization + + + + + Any process that modulates the frequency, rate or extent of biomineralization, the formation and deposition of mineral crystals by living organisms. + PMID:22992051 + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of biomineralization, the formation and deposition of mineral crystals by living organisms. + kmv + 2019-06-10T18:12:24Z + negative regulation of biomineralisation + negative regulation of mineralisation + negative regulation of mineralization + negative regulation of biomineral formation + biological_process + GO:0110150 + negative regulation of biomineralization + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of biomineralization, the formation and deposition of mineral crystals by living organisms. + PMID:22992051 + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of biomineralization, the formation and deposition of mineral crystals by living organisms. + kmv + 2019-06-10T18:18:01Z + positive regulation of biomineralisation + positive regulation of mineralisation + positive regulation of mineralization + positive regulation of biomineral formation + biological_process + GO:0110151 + positive regulation of biomineralization + + + + + Any process that activates or increases the frequency, rate or extent of biomineralization, the formation and deposition of mineral crystals by living organisms. + PMID:22992051 + + + + + + + + + + A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex. + kmv + 2019-08-12T18:01:37Z + cellular_component + GO:0110165 + cellular anatomical entity + + + + + A part of a cellular organism that is either an immaterial entity or a material entity with granularity above the level of a protein complex but below that of an anatomical system. Or, a substance produced by a cellular organism with granularity above the level of a protein complex. + GOC:kmv + + + + + + + + + + + + + + + + + + + Binding to somatostatin, a polypeptide hormone involved in regulating pancreatic alpha and pancreatic beta cells and controlling growth hormone secretion as well as many other functions. Somatostatin is produced by several cell types including pancreatic delta cells. There are several different mature forms of somatostatin. + https://github.com/geneontology/go-ontology/issues/13143 + krc + 2017-03-17T14:54:21Z + molecular_function + GO:0120023 + somatostatin binding + + + + + Binding to somatostatin, a polypeptide hormone involved in regulating pancreatic alpha and pancreatic beta cells and controlling growth hormone secretion as well as many other functions. Somatostatin is produced by several cell types including pancreatic delta cells. There are several different mature forms of somatostatin. + GOC:cvs + PMID:20472043 + + + + + + + + + + + + + + + + + + + A prolongation or process extending from a cell and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon. + https://github.com/geneontology/go-ontology/issues/13193 + krc + 2017-03-21T17:26:07Z + cellular_component + GO:0120025 + plasma membrane bounded cell projection + + + + + A prolongation or process extending from a cell and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon. + GOC:krc + + + + + + + + + + + + + + + + + + + Formation of a prolongation or process extending and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon. + https://github.com/geneontology/go-ontology/issues/13298 + krc + 2017-04-24T23:56:08Z + eupodium + biological_process + GO:0120031 + plasma membrane bounded cell projection assembly + + + + + Formation of a prolongation or process extending and that is bounded by plasma membrane, e.g. a cilium, lamellipodium, or axon. + GOC:krc + + + + + eupodium + GOC:krc + GOC:rjd + PMID:10328951 + PMID:9096956 + + + + + + + + + + + + + + + + + + + Any process that modulates the rate, frequency, or extent of plasma membrane bounded cell projection assembly. + https://github.com/geneontology/go-ontology/issues/13298 + krc + 2017-04-26T04:27:04Z + biological_process + GO:0120032 + regulation of plasma membrane bounded cell projection assembly + + + + + Any process that modulates the rate, frequency, or extent of plasma membrane bounded cell projection assembly. + GOC:krc + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane bounded cell projection assembly. + https://github.com/geneontology/go-ontology/issues/13298 + krc + 2017-04-26T04:34:31Z + biological_process + GO:0120033 + negative regulation of plasma membrane bounded cell projection assembly + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane bounded cell projection assembly. + GOC:krc + + + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of plasma membrane bounded cell projection assembly. + https://github.com/geneontology/go-ontology/issues/13298 + krc + 2017-04-26T04:34:45Z + biological_process + GO:0120034 + positive regulation of plasma membrane bounded cell projection assembly + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that activates or increases the frequency, rate or extent of plasma membrane bounded cell projection assembly. + GOC:krc + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of plasma membrane bounded cell projections. + https://github.com/geneontology/go-ontology/issues/13298 + krc + 2017-04-26T16:02:06Z + biological_process + GO:0120035 + regulation of plasma membrane bounded cell projection organization + + + + + Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of plasma membrane bounded cell projections. + GOC:krc + + + + + + + + + + + + + + + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasma membrane bounded prolongation or process extending from a cell, e.g. a cilium or axon. + https://github.com/geneontology/go-ontology/issues/13298 + krc + 2017-04-26T16:07:02Z + biological_process + GO:0120036 + plasma membrane bounded cell projection organization + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasma membrane bounded prolongation or process extending from a cell, e.g. a cilium or axon. + GOC:krc + + + + + + + + + + + + + + + + + + + + The process in which the anatomical structures of a plasma membrane bounded cell projection are generated and organized. + https://github.com/geneontology/go-ontology/issues/13298 + krc + 2017-04-28T23:39:37Z + biological_process + GO:0120039 + plasma membrane bounded cell projection morphogenesis + + + + + The process in which the anatomical structures of a plasma membrane bounded cell projection are generated and organized. + GOC:krc + + + + + + + + + + + + + + + + + + + All of the contents of a plasma membrane bounded neuron projection, excluding the plasma membrane surrounding the projection. + krc + 2017-11-01T18:58:12Z + cellular_component + GO:0120111 + neuron projection cytoplasm + + + + + All of the contents of a plasma membrane bounded neuron projection, excluding the plasma membrane surrounding the projection. + GOC:ha + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix. + krc + 2018-05-11T16:31:42Z + positive regulation of collagen breakdown + positive regulation of collagen catabolism + positive regulation of collagen degradation + up regulation of collagen catabolic process + up-regulation of collagen catabolic process + upregulation of collagen catabolic process + activation of collagen catabolic process + biological_process + GO:0120158 + positive regulation of collagen catabolic process + + + + + Any process that activates or increases the frequency, rate or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix. + GOC:dph + GOC:tb + + + + + positive regulation of collagen breakdown + GOC:dph + GOC:tb + + + + + positive regulation of collagen catabolism + GOC:dph + GOC:tb + + + + + positive regulation of collagen degradation + GOC:dph + GOC:tb + + + + + up regulation of collagen catabolic process + GOC:dph + GOC:tb + + + + + up-regulation of collagen catabolic process + GOC:dph + GOC:tb + + + + + upregulation of collagen catabolic process + GOC:dph + GOC:tb + + + + + activation of collagen catabolic process + GOC:dph + GOC:tb + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of any steroid hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone. + krc + 2019-05-20T22:34:00Z + biological_process + GO:0120178 + steroid hormone biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of any steroid hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone. + GOC:krc + GOC:nln + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue. + krc + 2018-07-16T22:28:58Z + biological_process + GO:0120188 + regulation of bile acid secretion + + + + + Any process that modulates the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue. + GOC:BHF + GOC:BHF_miRNA + GOC:rph + PMID:22767443 + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue. + krc + 2018-07-16T22:36:17Z + biological_process + GO:0120189 + positive regulation of bile acid secretion + + + + + Any process that activates or increases the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue. + GOC:BHF + GOC:BHF_miRNA + GOC:rph + PMID:22767443 + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue. + krc + 2018-07-16T22:38:34Z + biological_process + GO:0120190 + negative regulation of bile acid secretion + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of the controlled release of bile acid from a cell or a tissue. + GOC:BHF + GOC:BHF_miRNA + GOC:rph + PMID:22767443 + + + + + + + + + + + + + + + + + + + + A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a tight junction. A tight junction seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other. + krc + 2018-08-14T22:48:05Z + occluding cell junction assembly + occluding junction assembly + biological_process + GO:0120192 + tight junction assembly + + + + + A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a tight junction. A tight junction seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other. + GOC:rl + + + + + occluding cell junction assembly + GOC:rl + + + + + occluding junction assembly + GOC:rl + + + + + + + + + + + + + + + + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a tight junction. A tight junction seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other. + krc + 2018-08-14T23:05:40Z + occluding cell junction organization + occluding junction organization + biological_process + GO:0120193 + tight junction organization + + + + + A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a tight junction. A tight junction seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other. + GOC:krc + GOC:rl + + + + + occluding cell junction organization + GOC:rl + + + + + + + + + + + + + + + + + + + The outer segment of a vertebrate cone photoreceptor that contains membrane discs that are contiguous with the ciliary membrane and containing opsin photoreceptor proteins. + krc + 2019-05-07T22:23:28Z + cellular_component + GO:0120199 + cone photoreceptor outer segment + + + + + The outer segment of a vertebrate cone photoreceptor that contains membrane discs that are contiguous with the ciliary membrane and containing opsin photoreceptor proteins. + GOC:krc + GOC:pde + PMID:19501669 + PMID:26574505 + PMID:6771304 + + + + + + + + + + + + + + + + + + + The outer segment of a vertebrate rod photoreceptor that contains sealed membrane discs that are not connected to the ciliary membrane and containing rhodopsin photoreceptor proteins. + krc + 2019-05-07T22:47:20Z + cellular_component + GO:0120200 + rod photoreceptor outer segment + + + + + The outer segment of a vertebrate rod photoreceptor that contains sealed membrane discs that are not connected to the ciliary membrane and containing rhodopsin photoreceptor proteins. + GOC:krc + GOC:pde + PMID:19501669 + PMID:26574505 + PMID:6771304 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of blastocyst development. + krc + 2020-02-17T19:59:20Z + biological_process + GO:0120222 + regulation of blastocyst development + + + + + Any process that modulates the frequency, rate or extent of blastocyst development. + GOC:krc + PMID:29593216 + + + + + + + + + + + + + + + + + + + + + + + + + + The process in which the larynx is generated and organized. The larynx is a continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration. + krc + 2020-02-22T01:42:04Z + laryngeal morphogenesis + biological_process + GO:0120223 + larynx morphogenesis + + + + + The process in which the larynx is generated and organized. The larynx is a continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration. + GOC:krc + PMID:28177282 + + + + + laryngeal morphogenesis + GOC:krc + PMID:28177282 + + + + + + + + + + + + + + + + + + + + + + + + + + + The biological process whose specific outcome is the progression of a larynx from an initial condition to its mature state. This process begins with the formation of the larynx and ends with the mature structure. A larynx is a continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration. + krc + 2020-02-24T17:13:10Z + biological_process + GO:0120224 + larynx development + + + + + The biological process whose specific outcome is the progression of a larynx from an initial condition to its mature state. This process begins with the formation of the larynx and ends with the mature structure. A larynx is a continuation of the pharynx that is involved in breathing, sound production, and protecting the trachea against food aspiration. + GOC:krc + PMID:28177282 + + + + + + + + + + + + + + + + + + + + A process in which a protein is transported to, or maintained in, a location within a motile cilium. + https://github.com/geneontology/go-ontology/issues/19588 + krc + 2020-06-05T23:43:04Z + biological_process + protein localization to nonmotile primary cilium + GO:0120229 + protein localization to motile cilium + + + + + A process in which a protein is transported to, or maintained in, a location within a motile cilium. + GOC:krc + PMID:27486780 + + + + + + + + + + + + + + + + + + + + The flow of blood through the network of arteries and veins supplying the cerebrum, enabling the transport of nutrients to the tissues and the removal of waste products. + https://github.com/geneontology/go-ontology/issues/20107 + krc + 2020-10-20T19:13:51Z + cerebrum blood circulation + telencephelon blood circulation + biological_process + GO:0120275 + cerebral blood circulation + + + + + The flow of blood through the network of arteries and veins supplying the cerebrum, enabling the transport of nutrients to the tissues and the removal of waste products. + GOC:krc + PMID:25397684 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of cerebral blood circulation. + https://github.com/geneontology/go-ontology/issues/20107 + krc + 2020-10-21T06:52:22Z + regulation of cerebrum blood circulation + regulation of telencephalon blood circulation + biological_process + GO:0120276 + regulation of cerebral blood circulation + + + + + Any process that modulates the frequency, rate or extent of cerebral blood circulation. + GOC:krc + PMID:25397684 + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of cerebral blood circulation. + https://github.com/geneontology/go-ontology/issues/20107 + krc + 2020-10-21T06:55:42Z + positive regulation of cerebrum blood circulation + positive regulation of telencephalon blood circulation + up regulation of cerebral blood circulation + up-regulation of cerebral blood circulation + upregulation of cerebral blood circulation + activation of cerebral blood circulation + biological_process + GO:0120277 + positive regulation of cerebral blood circulation + + + + + Any process that activates or increases the frequency, rate or extent of cerebral blood circulation. + GOC:krc + PMID:25397684 + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cerebral blood circulation. + https://github.com/geneontology/go-ontology/issues/20107 + krc + 2020-10-21T07:02:05Z + down regulation of cerebral blood circulation + down-regulation of cerebral blood circulation + downregulation of cerebral blood circulation + negative regulation of cerebrum blood circulation + negative regulation of telencephalon blood circulation + inhibition of cerebral blood circulation + biological_process + GO:0120278 + negative regulation of cerebral blood circulation + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cerebral blood circulation. + GOC:krc + PMID:25397684 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of the deposition or modulates the distribution of coloring matter in an organism. + https://github.com/geneontology/go-ontology/issues/20524 + krc + 2021-02-09T19:37:35Z + biological_process + GO:0120305 + regulation of pigmentation + + + + + Any process that modulates the frequency, rate or extent of the deposition or modulates the distribution of coloring matter in an organism. + GOC:krc + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The assembly and organization of the sperm flagellum, the microtubule-based axoneme and associated structures that are part of a sperm flagellum (or cilium). + krc + 2021-04-29T01:27:27Z + biological_process + GO:0120316 + sperm flagellum assembly + + + + + The assembly and organization of the sperm flagellum, the microtubule-based axoneme and associated structures that are part of a sperm flagellum (or cilium). + GOC:krc + PMID:32791035 + + + + + + + + + + + + + + + + + + + One of the two nuclear divisions that occur as part of the meiotic cell cycle. + https://github.com/geneontology/go-ontology/issues/19910 + pg + 2017-03-23T09:40:00Z + meiosis + biological_process + GO:0140013 + + meiotic nuclear division + + + + + One of the two nuclear divisions that occur as part of the meiotic cell cycle. + PMID:9334324 + + + + + + + + + + + + + + + + + + + The cellular processes that contribute to exocytosis. + pg + 2017-05-15T13:20:45Z + biological_process + GO:0140029 + + exocytic process + + + + + The cellular processes that contribute to exocytosis. + Wikipedia:Exocytosis + + + + + + + + + + The process by which an organelle membrane interacts with another membrane via molecular tethers that physically bridge the two membranes and attach them to each other. + pg + 2017-06-27T09:58:51Z + biological_process + GO:0140056 + + organelle localization by membrane tethering + + + + + The process by which an organelle membrane interacts with another membrane via molecular tethers that physically bridge the two membranes and attach them to each other. + PMID:27875684 + + + + + + + + + + + + + + + + + + + Any process that controls lipoprotein transport. + pg + 2017-07-21T15:35:47Z + biological_process + GO:0140075 + regulation of lipoprotein transport + + + + + Any process that controls lipoprotein transport. + GOC:BHF + GOC:BHF_miRNA + GOC:RPH + PMID:26501192 + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of lipoprotein transport. + pg + 2017-07-21T15:39:50Z + biological_process + GO:0140076 + negative regulation of lipoprotein transport + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of lipoprotein transport. + GOC:BHF + GOC:BHF_miRNA + GOC:RPH + PMID:26501192 + + + + + + + + + + + + + + + + + + + Any process that activates or increases the rate or extent of lipoprotein transport. + pg + 2017-07-21T15:41:54Z + biological_process + GO:0140077 + positive regulation of lipoprotein transport + + + + + Any process that activates or increases the rate or extent of lipoprotein transport. + GOC:BHF + GOC:BHF_miRNA + GOC:RPH + PMID:26501192 + + + + + + + + + + + + + + + + + + + Catalytic activity that acts to modify a protein. + https://github.com/geneontology/go-ontology/issues/14225 + pg + 2017-09-14T10:32:59Z + molecular_function + GO:0140096 + + + catalytic activity, acting on a protein + + + + + Catalytic activity that acts to modify a protein. + GOC:molecular_function_refactoring + GOC:pdt + + + + + + + + + + + + + + + + + + + Catalysis of a biochemical reaction at physiological temperatures in which one of the substrates is a glycoprotein. + https://github.com/geneontology/go-ontology/issues/14225 + pg + 2017-09-15T19:27:54Z + molecular_function + GO:0140103 + catalytic activity, acting on a glycoprotein + + + + + Catalysis of a biochemical reaction at physiological temperatures in which one of the substrates is a glycoprotein. + GOC:molecular_function_refactoring + GOC:pdt + + + + + + + + + + + + + + + A cellular process in which two or more cells combine together, their plasma membrane fusing, producing a single cell. In some cases, nuclei fuse, producing a polyploid cell, while in other cases, nuclei remain separate, producing a syncytium. + https://github.com/geneontology/go-ontology/issues/15939 + pg + 2018-08-13T18:38:18Z + cell fusion + cell cell fusion + biological_process + GO:0140253 + cell-cell fusion + + + + + A cellular process in which two or more cells combine together, their plasma membrane fusing, producing a single cell. In some cases, nuclei fuse, producing a polyploid cell, while in other cases, nuclei remain separate, producing a syncytium. + Wikipedia:Cell_fusion + + + + + + + + + + + + + + + + + + + + + + + + The directed movement of some substance from a cell, into the extracellular region. This may occur via transport across the plasma membrane or via exocytosis. + pg + 2019-05-22T11:20:45Z + efflux + biological_process + GO:0140352 + export from cell + + + + + The directed movement of some substance from a cell, into the extracellular region. This may occur via transport across the plasma membrane or via exocytosis. + GOC:pg + + + + + + + + + + + + + + + + + + + + + + + + + + + The directed movement of a lipid from a cell, into the extracellular region. + pg + 2019-05-22T11:33:07Z + lipid efflux + biological_process + GO:0140353 + lipid export from cell + + + + + The directed movement of a lipid from a cell, into the extracellular region. + GOC:pg + + + + + + + + + + + + + + + + + + + + + + + + + + + The directed movement of a lipid from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis. + pg + 2019-05-22T11:38:15Z + lipid uptake + biological_process + GO:0140354 + lipid import into cell + + + + + The directed movement of a lipid from outside of a cell into a cell. This may occur via transport across the plasma membrane or via endocytosis. + GOC:pg + + + + + + + + + + + + + + + + + + + A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together in the nucleus. + pg + 2020-09-09T05:12:38Z + nuclear complex + cellular_component + GO:0140513 + + nuclear protein-containing complex + + + + + A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together in the nucleus. + GOC:pg + + + + + + + + + + + + + + + + + + + + The division of a vacuole within a cell to form two or more separate vacuoles. + https://github.com/geneontology/go-ontology/issues/20639 + pg + 2021-01-04T10:17:58Z + biological_process + GO:0140572 + vacuole fission + + + + + The division of a vacuole within a cell to form two or more separate vacuoles. + PMID:19643199 + + + + + + + + + + + + + + + + + + + + The radial migration of a pyramidal neuron along radial glial cells. + https://github.com/geneontology/go-ontology/issues/21476 + pg + 2021-05-25T12:48:12Z + radial glia-dependent neuronal migration + biological_process + GO:0140650 + radial glia-guided pyramidal neuron migration + + + + + The radial migration of a pyramidal neuron along radial glial cells. + PMID:3760547 + + + + + + + + + + + + + + + + + + + The aggregation, arrangement and bonding together of a set of components to form a non-membrane-bounded organelle. + https://github.com/geneontology/go-ontology/issues/21939 + pg + 2021-08-09T15:30:06Z + non-membrane-bounded organelle formation + non-membrane-enclosed organelle assembly + non-membrane-enclosed organelle formation + biological_process + GO:0140694 + non-membrane-bounded organelle assembly + + + + + The aggregation, arrangement and bonding together of a set of components to form a non-membrane-bounded organelle. + PMID:28225081 + + + + + + + + + + + + + + + + + + + The elimination of ammonium ions from an excretory cell. + https://github.com/geneontology/go-ontology/issues/22368 + pg + 2021-11-24T17:55:51Z + biological_process + ammonia excretion + GO:0140734 + ammonium excretion + + + + + The elimination of ammonium ions from an excretory cell. + PMID:25740900 + + + + + + + + + + + + + + + + + + + A protein complex capable of activating an enzyme. Activating subunits may dissociate from the catalytic unit before the enzyme is active. + cellular_component + GO:0150005 + enzyme activator complex + + + + + A protein complex capable of activating an enzyme. Activating subunits may dissociate from the catalytic unit before the enzyme is active. + GOC:bhm + PMID:16244137 + PMID:28710280 + + + + + + + + + The process whose specific outcome is the progression of the visual system over time, from its formation to the mature structure, including the eye, parts of the central nervous system (CNS) involved in processing of visual inputs, and connecting nerve pathways. + bc + 2018-07-23T10:31:58Z + biological_process + optic pathway development + visual pathway development + GO:0150063 + visual system development + + + + + The process whose specific outcome is the progression of the visual system over time, from its formation to the mature structure, including the eye, parts of the central nervous system (CNS) involved in processing of visual inputs, and connecting nerve pathways. + GOC:aruk + GOC:bc + GOC:krc + PMID:15004427 + PMID:20647017 + PMID:22632727 + + + + + + + + + The immediate defensive reaction by neural vertebrate tissue to infection or injury caused by chemical or physical agents. + bc + 2018-07-26T12:25:34Z + nerve tissue inflammatory response + nervous tissue inflammatory response + neural tissue inflammatory response + biological_process + GO:0150076 + neuroinflammatory response + + + + + The immediate defensive reaction by neural vertebrate tissue to infection or injury caused by chemical or physical agents. + GOC:aruk + GOC:bc + PMID:10981966 + PMID:11099416 + PMID:18164423 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of neuroinflammatory response. + bc + 2018-07-26T12:32:18Z + biological_process + GO:0150077 + regulation of neuroinflammatory response + + + + + Any process that modulates the frequency, rate or extent of neuroinflammatory response. + GOC:aruk + GOC:bc + PMID:10981966 + PMID:11099416 + PMID:18164423 + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of neuroinflammatory response. + bc + 2018-07-26T12:35:50Z + biological_process + GO:0150078 + positive regulation of neuroinflammatory response + + + + + Any process that activates or increases the frequency, rate or extent of neuroinflammatory response. + GOC:aruk + GOC:bc + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of neuroinflammatory response. + bc + 2018-07-26T12:38:08Z + biological_process + GO:0150079 + negative regulation of neuroinflammatory response + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of neuroinflammatory response. + GOC:aruk + GOC:bc + PMID:11099416 + PMID:18164423 + + + + + + + + + + + + + + + + + + + A process in which a protein is transported to, or maintained, in a location within a cell-cell junction. + bc + 2019-06-11T11:00:18Z + biological_process + GO:0150105 + protein localization to cell-cell junction + + + + + A process in which a protein is transported to, or maintained, in a location within a cell-cell junction. + GOC:aruk + GOC:bc + PMID:26706435 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of protein localization to cell-cell junction. + bc + 2019-06-11T11:17:15Z + biological_process + GO:0150106 + regulation of protein localization to cell-cell junction + + + + + Any process that modulates the frequency, rate or extent of protein localization to cell-cell junction. + GOC:aruk + GOC:bc + PMID:26706435 + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of protein localization to cell-cell junction. + bc + 2019-06-11T11:23:58Z + biological_process + GO:0150107 + positive regulation of protein localization to cell-cell junction + + + + + Any process that activates or increases the frequency, rate or extent of protein localization to cell-cell junction. + GOC:aruk + GOC:bc + PMID:26706435 + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell-cell junction. + bc + 2019-11-21T13:53:34Z + negative regulation of protein localisation to cell-cell junction + biological_process + GO:0150119 + negative regulation of protein localization to cell-cell junction + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell-cell junction. + GOC:aruk + GOC:bc + + + + + + + + + + + + + + + + + + + The multiplication or reproduction of Leydig cells, resulting in the expansion of a cell population. Leydig cells are interstitial cells located adjacent to the seminiferous tubules in the testis which produce testosterone. + rynl + 2022-02-08T20:09:53Z + biological_process + GO:0160024 + Leydig cell proliferation + + + + + The multiplication or reproduction of Leydig cells, resulting in the expansion of a cell population. Leydig cells are interstitial cells located adjacent to the seminiferous tubules in the testis which produce testosterone. + PMID:29632025 + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of dendrite development. + hjd + 2012-01-09T10:41:31Z + biological_process + up regulation of dendrite development + GO:1900006 + positive regulation of dendrite development + + + + + Any process that activates or increases the frequency, rate or extent of dendrite development. + GOC:TermGenie + + + + + up regulation of dendrite development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of hemostasis. + jl + 2012-01-19T03:23:38Z + biological_process + GO:1900046 + regulation of hemostasis + + + + + Any process that modulates the frequency, rate or extent of hemostasis. + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of hemostasis. + jl + 2012-01-19T03:23:42Z + down regulation of hemostasis + down-regulation of hemostasis + downregulation of hemostasis + inhibition of hemostasis + biological_process + GO:1900047 + negative regulation of hemostasis + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of hemostasis. + GOC:TermGenie + + + + + down regulation of hemostasis + GOC:TermGenie + + + + + down-regulation of hemostasis + GOC:TermGenie + + + + + downregulation of hemostasis + GOC:TermGenie + + + + + inhibition of hemostasis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of hemostasis. + jl + 2012-01-19T03:23:45Z + up regulation of hemostasis + up-regulation of hemostasis + upregulation of hemostasis + activation of hemostasis + biological_process + GO:1900048 + positive regulation of hemostasis + + + + + Any process that activates or increases the frequency, rate or extent of hemostasis. + GOC:TermGenie + + + + + up regulation of hemostasis + GOC:TermGenie + + + + + up-regulation of hemostasis + GOC:TermGenie + + + + + upregulation of hemostasis + GOC:TermGenie + + + + + activation of hemostasis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of cellular response to insulin stimulus. + yaf + 2012-01-31T11:22:22Z + biological_process + GO:1900076 + regulation of cellular response to insulin stimulus + + + + + Any process that modulates the frequency, rate or extent of cellular response to insulin stimulus. + GOC:TermGenie + GOC:yaf + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to insulin stimulus. + yaf + 2012-01-31T11:23:15Z + down regulation of cellular response to insulin stimulus + down-regulation of cellular response to insulin stimulus + downregulation of cellular response to insulin stimulus + inhibition of cellular response to insulin stimulus + biological_process + GO:1900077 + negative regulation of cellular response to insulin stimulus + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to insulin stimulus. + GOC:TermGenie + GOC:yaf + + + + + down regulation of cellular response to insulin stimulus + GOC:TermGenie + + + + + down-regulation of cellular response to insulin stimulus + GOC:TermGenie + + + + + downregulation of cellular response to insulin stimulus + GOC:TermGenie + + + + + inhibition of cellular response to insulin stimulus + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of cellular response to insulin stimulus. + yaf + 2012-01-31T11:24:30Z + up regulation of cellular response to insulin stimulus + up-regulation of cellular response to insulin stimulus + upregulation of cellular response to insulin stimulus + activation of cellular response to insulin stimulus + biological_process + GO:1900078 + positive regulation of cellular response to insulin stimulus + + + + + Any process that activates or increases the frequency, rate or extent of cellular response to insulin stimulus. + GOC:TermGenie + GOC:yaf + + + + + up regulation of cellular response to insulin stimulus + GOC:TermGenie + + + + + up-regulation of cellular response to insulin stimulus + GOC:TermGenie + + + + + upregulation of cellular response to insulin stimulus + GOC:TermGenie + + + + + activation of cellular response to insulin stimulus + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of plasma cell differentiation. + bf + 2012-02-15T10:46:00Z + biological_process + regulation of plasma cell development + GO:1900098 + regulation of plasma cell differentiation + + + + + Any process that modulates the frequency, rate or extent of plasma cell differentiation. + GOC:TermGenie + + + + + regulation of plasma cell development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of plasma cell differentiation. + bf + 2012-02-15T10:46:05Z + down regulation of plasma cell differentiation + down-regulation of plasma cell differentiation + downregulation of plasma cell differentiation + inhibition of plasma cell differentiation + biological_process + down regulation of plasma cell development + down-regulation of plasma cell development + downregulation of plasma cell development + inhibition of plasma cell development + negative regulation of plasma cell development + GO:1900099 + negative regulation of plasma cell differentiation + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of plasma cell differentiation. + GOC:TermGenie + + + + + down regulation of plasma cell differentiation + GOC:TermGenie + + + + + down-regulation of plasma cell differentiation + GOC:TermGenie + + + + + downregulation of plasma cell differentiation + GOC:TermGenie + + + + + inhibition of plasma cell differentiation + GOC:TermGenie + + + + + down regulation of plasma cell development + GOC:TermGenie + + + + + down-regulation of plasma cell development + GOC:TermGenie + + + + + downregulation of plasma cell development + GOC:TermGenie + + + + + inhibition of plasma cell development + GOC:TermGenie + + + + + negative regulation of plasma cell development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of plasma cell differentiation. + bf + 2012-02-15T10:46:08Z + up regulation of plasma cell differentiation + up-regulation of plasma cell differentiation + upregulation of plasma cell differentiation + activation of plasma cell differentiation + biological_process + activation of plasma cell development + positive regulation of plasma cell development + up regulation of plasma cell development + up-regulation of plasma cell development + upregulation of plasma cell development + GO:1900100 + positive regulation of plasma cell differentiation + + + + + Any process that activates or increases the frequency, rate or extent of plasma cell differentiation. + GOC:TermGenie + + + + + up regulation of plasma cell differentiation + GOC:TermGenie + + + + + up-regulation of plasma cell differentiation + GOC:TermGenie + + + + + upregulation of plasma cell differentiation + GOC:TermGenie + + + + + activation of plasma cell differentiation + GOC:TermGenie + + + + + activation of plasma cell development + GOC:TermGenie + + + + + positive regulation of plasma cell development + GOC:TermGenie + + + + + up regulation of plasma cell development + GOC:TermGenie + + + + + up-regulation of plasma cell development + GOC:TermGenie + + + + + upregulation of plasma cell development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any regulation of signal transduction that takes place in the extracellular region. + bf + 2012-02-22T10:21:48Z + regulation of signaling pathway in extracellular region + regulation of signalling pathway in extracellular region + biological_process + GO:1900115 + extracellular regulation of signal transduction + + + + + Any regulation of signal transduction that takes place in the extracellular region. + GOC:TermGenie + GOC:signaling + + + + + regulation of signaling pathway in extracellular region + GOC:TermGenie + + + + + regulation of signalling pathway in extracellular region + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any negative regulation of signal transduction that takes place in extracellular region. + bf + 2012-02-22T10:27:56Z + down regulation of signal transduction in extracellular region + down-regulation of signal transduction in extracellular region + downregulation of signal transduction in extracellular region + negative regulation of signaling pathway in extracellular region + negative regulation of signalling pathway in extracellular region + extracellular inhibition of signaling pathway + inhibition of signal transduction in extracellular region + biological_process + GO:1900116 + extracellular negative regulation of signal transduction + + + + + Any negative regulation of signal transduction that takes place in extracellular region. + GOC:TermGenie + GOC:signaling + + + + + down regulation of signal transduction in extracellular region + GOC:TermGenie + + + + + down-regulation of signal transduction in extracellular region + GOC:TermGenie + + + + + downregulation of signal transduction in extracellular region + GOC:TermGenie + + + + + negative regulation of signaling pathway in extracellular region + GOC:TermGenie + + + + + negative regulation of signalling pathway in extracellular region + GOC:TermGenie + + + + + extracellular inhibition of signaling pathway + GOC:bf + + + + + inhibition of signal transduction in extracellular region + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of hyaluronan biosynthetic process. + yaf + 2012-02-23T01:09:21Z + regulation of hyaluronan anabolism + regulation of hyaluronan biosynthesis + regulation of hyaluronan formation + regulation of hyaluronan synthesis + biological_process + GO:1900125 + regulation of hyaluronan biosynthetic process + + + + + Any process that modulates the frequency, rate or extent of hyaluronan biosynthetic process. + GOC:TermGenie + GOC:yaf + + + + + regulation of hyaluronan anabolism + GOC:TermGenie + + + + + regulation of hyaluronan biosynthesis + GOC:TermGenie + + + + + regulation of hyaluronan formation + GOC:TermGenie + + + + + regulation of hyaluronan synthesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of hyaluronan biosynthetic process. + yaf + 2012-02-23T01:09:29Z + down regulation of hyaluronan anabolism + down regulation of hyaluronan biosynthesis + down regulation of hyaluronan biosynthetic process + down regulation of hyaluronan formation + down regulation of hyaluronan synthesis + down-regulation of hyaluronan anabolism + down-regulation of hyaluronan biosynthesis + down-regulation of hyaluronan biosynthetic process + down-regulation of hyaluronan formation + down-regulation of hyaluronan synthesis + downregulation of hyaluronan anabolism + downregulation of hyaluronan biosynthesis + downregulation of hyaluronan biosynthetic process + downregulation of hyaluronan formation + downregulation of hyaluronan synthesis + inhibition of hyaluronan anabolism + inhibition of hyaluronan biosynthesis + inhibition of hyaluronan formation + inhibition of hyaluronan synthesis + negative regulation of hyaluronan anabolism + negative regulation of hyaluronan biosynthesis + negative regulation of hyaluronan formation + negative regulation of hyaluronan synthesis + inhibition of hyaluronan biosynthetic process + biological_process + GO:1900126 + negative regulation of hyaluronan biosynthetic process + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of hyaluronan biosynthetic process. + GOC:TermGenie + GOC:yaf + + + + + down regulation of hyaluronan anabolism + GOC:TermGenie + + + + + down regulation of hyaluronan biosynthesis + GOC:TermGenie + + + + + down regulation of hyaluronan biosynthetic process + GOC:TermGenie + + + + + down regulation of hyaluronan formation + GOC:TermGenie + + + + + down regulation of hyaluronan synthesis + GOC:TermGenie + + + + + down-regulation of hyaluronan anabolism + GOC:TermGenie + + + + + down-regulation of hyaluronan biosynthesis + GOC:TermGenie + + + + + down-regulation of hyaluronan biosynthetic process + GOC:TermGenie + + + + + down-regulation of hyaluronan formation + GOC:TermGenie + + + + + down-regulation of hyaluronan synthesis + GOC:TermGenie + + + + + downregulation of hyaluronan anabolism + GOC:TermGenie + + + + + downregulation of hyaluronan biosynthesis + GOC:TermGenie + + + + + downregulation of hyaluronan biosynthetic process + GOC:TermGenie + + + + + downregulation of hyaluronan formation + GOC:TermGenie + + + + + downregulation of hyaluronan synthesis + GOC:TermGenie + + + + + inhibition of hyaluronan anabolism + GOC:TermGenie + + + + + inhibition of hyaluronan biosynthesis + GOC:TermGenie + + + + + inhibition of hyaluronan formation + GOC:TermGenie + + + + + inhibition of hyaluronan synthesis + GOC:TermGenie + + + + + negative regulation of hyaluronan anabolism + GOC:TermGenie + + + + + negative regulation of hyaluronan biosynthesis + GOC:TermGenie + + + + + negative regulation of hyaluronan formation + GOC:TermGenie + + + + + negative regulation of hyaluronan synthesis + GOC:TermGenie + + + + + inhibition of hyaluronan biosynthetic process + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of hyaluronan biosynthetic process. + yaf + 2012-02-23T01:09:33Z + activation of hyaluronan anabolism + activation of hyaluronan biosynthesis + activation of hyaluronan formation + activation of hyaluronan synthesis + positive regulation of hyaluronan anabolism + positive regulation of hyaluronan biosynthesis + positive regulation of hyaluronan formation + positive regulation of hyaluronan synthesis + up regulation of hyaluronan anabolism + up regulation of hyaluronan biosynthesis + up regulation of hyaluronan biosynthetic process + up regulation of hyaluronan formation + up regulation of hyaluronan synthesis + up-regulation of hyaluronan anabolism + up-regulation of hyaluronan biosynthesis + up-regulation of hyaluronan biosynthetic process + up-regulation of hyaluronan formation + up-regulation of hyaluronan synthesis + upregulation of hyaluronan anabolism + upregulation of hyaluronan biosynthesis + upregulation of hyaluronan biosynthetic process + upregulation of hyaluronan formation + upregulation of hyaluronan synthesis + activation of hyaluronan biosynthetic process + biological_process + GO:1900127 + positive regulation of hyaluronan biosynthetic process + + + + + Any process that activates or increases the frequency, rate or extent of hyaluronan biosynthetic process. + GOC:TermGenie + GOC:yaf + + + + + activation of hyaluronan anabolism + GOC:TermGenie + + + + + activation of hyaluronan biosynthesis + GOC:TermGenie + + + + + activation of hyaluronan formation + GOC:TermGenie + + + + + activation of hyaluronan synthesis + GOC:TermGenie + + + + + positive regulation of hyaluronan anabolism + GOC:TermGenie + + + + + positive regulation of hyaluronan biosynthesis + GOC:TermGenie + + + + + positive regulation of hyaluronan formation + GOC:TermGenie + + + + + positive regulation of hyaluronan synthesis + GOC:TermGenie + + + + + up regulation of hyaluronan anabolism + GOC:TermGenie + + + + + up regulation of hyaluronan biosynthesis + GOC:TermGenie + + + + + up regulation of hyaluronan biosynthetic process + GOC:TermGenie + + + + + up regulation of hyaluronan formation + GOC:TermGenie + + + + + up regulation of hyaluronan synthesis + GOC:TermGenie + + + + + up-regulation of hyaluronan anabolism + GOC:TermGenie + + + + + up-regulation of hyaluronan biosynthesis + GOC:TermGenie + + + + + up-regulation of hyaluronan biosynthetic process + GOC:TermGenie + + + + + up-regulation of hyaluronan formation + GOC:TermGenie + + + + + up-regulation of hyaluronan synthesis + GOC:TermGenie + + + + + upregulation of hyaluronan anabolism + GOC:TermGenie + + + + + upregulation of hyaluronan biosynthesis + GOC:TermGenie + + + + + upregulation of hyaluronan biosynthetic process + GOC:TermGenie + + + + + upregulation of hyaluronan formation + GOC:TermGenie + + + + + upregulation of hyaluronan synthesis + GOC:TermGenie + + + + + activation of hyaluronan biosynthetic process + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of lipid binding. + pm + 2012-02-23T04:05:03Z + biological_process + GO:1900130 + regulation of lipid binding + + + + + Any process that modulates the frequency, rate or extent of lipid binding. + GOC:TermGenie + GOC:pm + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of lipid binding. + pm + 2012-02-23T04:05:07Z + down regulation of lipid binding + down-regulation of lipid binding + downregulation of lipid binding + inhibition of lipid binding + biological_process + GO:1900131 + negative regulation of lipid binding + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of lipid binding. + GOC:TermGenie + GOC:pm + + + + + down regulation of lipid binding + GOC:TermGenie + + + + + down-regulation of lipid binding + GOC:TermGenie + + + + + downregulation of lipid binding + GOC:TermGenie + + + + + inhibition of lipid binding + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of lipid binding. + pm + 2012-02-23T04:05:11Z + up regulation of lipid binding + up-regulation of lipid binding + upregulation of lipid binding + activation of lipid binding + biological_process + GO:1900132 + positive regulation of lipid binding + + + + + Any process that activates or increases the frequency, rate or extent of lipid binding. + GOC:TermGenie + GOC:pm + + + + + up regulation of lipid binding + GOC:TermGenie + + + + + up-regulation of lipid binding + GOC:TermGenie + + + + + upregulation of lipid binding + GOC:TermGenie + + + + + activation of lipid binding + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of Schwann cell migration. + bf + 2012-03-06T04:14:50Z + biological_process + GO:1900147 + regulation of Schwann cell migration + + + + + Any process that modulates the frequency, rate or extent of Schwann cell migration. + GOC:TermGenie + GOC:sjw + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell migration. + bf + 2012-03-06T04:14:55Z + down regulation of Schwann cell migration + down-regulation of Schwann cell migration + downregulation of Schwann cell migration + inhibition of Schwann cell migration + biological_process + GO:1900148 + negative regulation of Schwann cell migration + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell migration. + GOC:TermGenie + GOC:sjw + + + + + down regulation of Schwann cell migration + GOC:TermGenie + + + + + down-regulation of Schwann cell migration + GOC:TermGenie + + + + + downregulation of Schwann cell migration + GOC:TermGenie + + + + + inhibition of Schwann cell migration + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of Schwann cell migration. + bf + 2012-03-06T04:14:58Z + up regulation of Schwann cell migration + up-regulation of Schwann cell migration + upregulation of Schwann cell migration + activation of Schwann cell migration + biological_process + GO:1900149 + positive regulation of Schwann cell migration + + + + + Any process that activates or increases the frequency, rate or extent of Schwann cell migration. + GOC:TermGenie + GOC:sjw + + + + + up regulation of Schwann cell migration + GOC:TermGenie + + + + + up-regulation of Schwann cell migration + GOC:TermGenie + + + + + upregulation of Schwann cell migration + GOC:TermGenie + + + + + activation of Schwann cell migration + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of defense response to fungus. + dhl + 2012-03-06T10:00:16Z + GO:2000072 + regulation of defence response to fungi + regulation of defence response to fungus + regulation of defense response to fungi + regulation of defense response to fungi, incompatible interaction + regulation of defense response to fungus, incompatible interaction + regulation of resistance response to pathogenic fungi + regulation of resistance response to pathogenic fungus + regulation of response to pathogenic fungus (incompatible interaction) + biological_process + GO:1900150 + regulation of defense response to fungus + + + + + Any process that modulates the frequency, rate or extent of defense response to fungus. + GOC:TermGenie + GOC:dhl + PMID:22242006 + + + + + regulation of defence response to fungi + GOC:TermGenie + + + + + regulation of defence response to fungus + GOC:TermGenie + + + + + regulation of defense response to fungi + GOC:TermGenie + + + + + regulation of defense response to fungi, incompatible interaction + GOC:obol + + + + + regulation of resistance response to pathogenic fungi + GOC:obol + + + + + regulation of resistance response to pathogenic fungus + GOC:obol + + + + + regulation of response to pathogenic fungus (incompatible interaction) + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of bone trabecula formation. + vk + 2012-03-07T01:47:03Z + regulation of bone trabeculation + regulation of skeletal trabecula formation + regulation of skeletal trabeculation + biological_process + regulation of bone trabecula biogenesis + regulation of skeletal trabecula biogenesis + GO:1900154 + regulation of bone trabecula formation + + + + + Any process that modulates the frequency, rate or extent of bone trabecula formation. + GOC:BHF + GOC:TermGenie + + + + + regulation of bone trabeculation + GOC:TermGenie + + + + + regulation of skeletal trabecula formation + GOC:TermGenie + + + + + regulation of skeletal trabeculation + GOC:TermGenie + + + + + regulation of bone trabecula biogenesis + GOC:TermGenie + + + + + regulation of skeletal trabecula biogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of bone trabecula formation. + vk + 2012-03-07T01:47:07Z + down regulation of bone trabecula formation + down regulation of bone trabeculation + down regulation of skeletal trabecula formation + down regulation of skeletal trabeculation + down-regulation of bone trabecula formation + down-regulation of bone trabeculation + down-regulation of skeletal trabecula formation + down-regulation of skeletal trabeculation + downregulation of bone trabecula formation + downregulation of bone trabeculation + downregulation of skeletal trabecula formation + downregulation of skeletal trabeculation + negative regulation of bone trabeculation + negative regulation of skeletal trabecula formation + negative regulation of skeletal trabeculation + inhibition of bone trabecula formation + inhibition of bone trabeculation + inhibition of skeletal trabecula formation + inhibition of skeletal trabeculation + biological_process + down regulation of bone trabecula biogenesis + down regulation of skeletal trabecula biogenesis + down-regulation of bone trabecula biogenesis + down-regulation of skeletal trabecula biogenesis + downregulation of bone trabecula biogenesis + downregulation of skeletal trabecula biogenesis + inhibition of bone trabecula biogenesis + inhibition of skeletal trabecula biogenesis + negative regulation of bone trabecula biogenesis + negative regulation of skeletal trabecula biogenesis + GO:1900155 + negative regulation of bone trabecula formation + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of bone trabecula formation. + GOC:BHF + GOC:TermGenie + + + + + down regulation of bone trabecula formation + GOC:TermGenie + + + + + down regulation of bone trabeculation + GOC:TermGenie + + + + + down regulation of skeletal trabecula formation + GOC:TermGenie + + + + + down regulation of skeletal trabeculation + GOC:TermGenie + + + + + down-regulation of bone trabecula formation + GOC:TermGenie + + + + + down-regulation of bone trabeculation + GOC:TermGenie + + + + + down-regulation of skeletal trabecula formation + GOC:TermGenie + + + + + down-regulation of skeletal trabeculation + GOC:TermGenie + + + + + downregulation of bone trabecula formation + GOC:TermGenie + + + + + downregulation of bone trabeculation + GOC:TermGenie + + + + + downregulation of skeletal trabecula formation + GOC:TermGenie + + + + + downregulation of skeletal trabeculation + GOC:TermGenie + + + + + negative regulation of bone trabeculation + GOC:TermGenie + + + + + negative regulation of skeletal trabecula formation + GOC:TermGenie + + + + + negative regulation of skeletal trabeculation + GOC:TermGenie + + + + + inhibition of bone trabecula formation + GOC:TermGenie + + + + + inhibition of bone trabeculation + GOC:TermGenie + + + + + inhibition of skeletal trabecula formation + GOC:TermGenie + + + + + inhibition of skeletal trabeculation + GOC:TermGenie + + + + + down regulation of bone trabecula biogenesis + GOC:TermGenie + + + + + down regulation of skeletal trabecula biogenesis + GOC:TermGenie + + + + + down-regulation of bone trabecula biogenesis + GOC:TermGenie + + + + + down-regulation of skeletal trabecula biogenesis + GOC:TermGenie + + + + + downregulation of bone trabecula biogenesis + GOC:TermGenie + + + + + downregulation of skeletal trabecula biogenesis + GOC:TermGenie + + + + + inhibition of bone trabecula biogenesis + GOC:TermGenie + + + + + inhibition of skeletal trabecula biogenesis + GOC:TermGenie + + + + + negative regulation of bone trabecula biogenesis + GOC:TermGenie + + + + + negative regulation of skeletal trabecula biogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of bone trabecula formation. + vk + 2012-03-07T01:47:10Z + positive regulation of bone trabeculation + positive regulation of skeletal trabecula formation + positive regulation of skeletal trabeculation + up regulation of bone trabecula formation + up regulation of bone trabeculation + up regulation of skeletal trabecula formation + up regulation of skeletal trabeculation + up-regulation of bone trabecula formation + up-regulation of bone trabeculation + up-regulation of skeletal trabecula formation + up-regulation of skeletal trabeculation + upregulation of bone trabecula formation + upregulation of bone trabeculation + upregulation of skeletal trabecula formation + upregulation of skeletal trabeculation + activation of bone trabecula formation + activation of bone trabeculation + activation of skeletal trabecula formation + activation of skeletal trabeculation + biological_process + activation of bone trabecula biogenesis + activation of skeletal trabecula biogenesis + positive regulation of bone trabecula biogenesis + positive regulation of skeletal trabecula biogenesis + up regulation of bone trabecula biogenesis + up regulation of skeletal trabecula biogenesis + up-regulation of bone trabecula biogenesis + up-regulation of skeletal trabecula biogenesis + upregulation of bone trabecula biogenesis + upregulation of skeletal trabecula biogenesis + GO:1900156 + positive regulation of bone trabecula formation + + + + + Any process that activates or increases the frequency, rate or extent of bone trabecula formation. + GOC:BHF + GOC:TermGenie + + + + + positive regulation of bone trabeculation + GOC:TermGenie + + + + + positive regulation of skeletal trabecula formation + GOC:TermGenie + + + + + positive regulation of skeletal trabeculation + GOC:TermGenie + + + + + up regulation of bone trabecula formation + GOC:TermGenie + + + + + up regulation of bone trabeculation + GOC:TermGenie + + + + + up regulation of skeletal trabecula formation + GOC:TermGenie + + + + + up regulation of skeletal trabeculation + GOC:TermGenie + + + + + up-regulation of bone trabecula formation + GOC:TermGenie + + + + + up-regulation of bone trabeculation + GOC:TermGenie + + + + + up-regulation of skeletal trabecula formation + GOC:TermGenie + + + + + up-regulation of skeletal trabeculation + GOC:TermGenie + + + + + upregulation of bone trabecula formation + GOC:TermGenie + + + + + upregulation of bone trabeculation + GOC:TermGenie + + + + + upregulation of skeletal trabecula formation + GOC:TermGenie + + + + + upregulation of skeletal trabeculation + GOC:TermGenie + + + + + activation of bone trabecula formation + GOC:TermGenie + + + + + activation of bone trabeculation + GOC:TermGenie + + + + + activation of skeletal trabecula formation + GOC:TermGenie + + + + + activation of skeletal trabeculation + GOC:TermGenie + + + + + activation of bone trabecula biogenesis + GOC:TermGenie + + + + + activation of skeletal trabecula biogenesis + GOC:TermGenie + + + + + positive regulation of bone trabecula biogenesis + GOC:TermGenie + + + + + positive regulation of skeletal trabecula biogenesis + GOC:TermGenie + + + + + up regulation of bone trabecula biogenesis + GOC:TermGenie + + + + + up regulation of skeletal trabecula biogenesis + GOC:TermGenie + + + + + up-regulation of bone trabecula biogenesis + GOC:TermGenie + + + + + up-regulation of skeletal trabecula biogenesis + GOC:TermGenie + + + + + upregulation of bone trabecula biogenesis + GOC:TermGenie + + + + + upregulation of skeletal trabecula biogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of bone mineralization involved in bone maturation. + vk + 2012-03-07T08:55:07Z + biological_process + GO:1900157 + regulation of bone mineralization involved in bone maturation + + + + + Any process that modulates the frequency, rate or extent of bone mineralization involved in bone maturation. + GOC:BHF + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of bone mineralization involved in bone maturation. + vk + 2012-03-07T08:55:12Z + down regulation of bone mineralization involved in bone maturation + down-regulation of bone mineralization involved in bone maturation + downregulation of bone mineralization involved in bone maturation + inhibition of bone mineralization involved in bone maturation + biological_process + GO:1900158 + negative regulation of bone mineralization involved in bone maturation + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of bone mineralization involved in bone maturation. + GOC:BHF + GOC:TermGenie + + + + + down regulation of bone mineralization involved in bone maturation + GOC:TermGenie + + + + + down-regulation of bone mineralization involved in bone maturation + GOC:TermGenie + + + + + downregulation of bone mineralization involved in bone maturation + GOC:TermGenie + + + + + inhibition of bone mineralization involved in bone maturation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of bone mineralization involved in bone maturation. + vk + 2012-03-07T08:55:16Z + up regulation of bone mineralization involved in bone maturation + up-regulation of bone mineralization involved in bone maturation + upregulation of bone mineralization involved in bone maturation + activation of bone mineralization involved in bone maturation + biological_process + GO:1900159 + positive regulation of bone mineralization involved in bone maturation + + + + + Any process that activates or increases the frequency, rate or extent of bone mineralization involved in bone maturation. + GOC:BHF + GOC:TermGenie + + + + + up regulation of bone mineralization involved in bone maturation + GOC:TermGenie + + + + + up-regulation of bone mineralization involved in bone maturation + GOC:TermGenie + + + + + upregulation of bone mineralization involved in bone maturation + GOC:TermGenie + + + + + activation of bone mineralization involved in bone maturation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of glucocorticoid mediated signaling pathway. + hjd + 2012-03-08T08:33:16Z + regulation of glucocorticoid mediated signalling + biological_process + GO:1900169 + regulation of glucocorticoid mediated signaling pathway + + + + + Any process that modulates the frequency, rate or extent of glucocorticoid mediated signaling pathway. + GOC:TermGenie + + + + + regulation of glucocorticoid mediated signalling + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid mediated signaling pathway. + hjd + 2012-03-08T08:33:20Z + down regulation of glucocorticoid mediated signaling pathway + down regulation of glucocorticoid mediated signalling + down-regulation of glucocorticoid mediated signaling pathway + down-regulation of glucocorticoid mediated signalling + downregulation of glucocorticoid mediated signaling pathway + downregulation of glucocorticoid mediated signalling + negative regulation of glucocorticoid mediated signalling + inhibition of glucocorticoid mediated signaling pathway + inhibition of glucocorticoid mediated signalling + biological_process + GO:1900170 + negative regulation of glucocorticoid mediated signaling pathway + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid mediated signaling pathway. + GOC:TermGenie + + + + + down regulation of glucocorticoid mediated signaling pathway + GOC:TermGenie + + + + + down regulation of glucocorticoid mediated signalling + GOC:TermGenie + + + + + down-regulation of glucocorticoid mediated signaling pathway + GOC:TermGenie + + + + + down-regulation of glucocorticoid mediated signalling + GOC:TermGenie + + + + + downregulation of glucocorticoid mediated signaling pathway + GOC:TermGenie + + + + + downregulation of glucocorticoid mediated signalling + GOC:TermGenie + + + + + negative regulation of glucocorticoid mediated signalling + GOC:TermGenie + + + + + inhibition of glucocorticoid mediated signaling pathway + GOC:TermGenie + + + + + inhibition of glucocorticoid mediated signalling + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of glucocorticoid mediated signaling pathway. + hjd + 2012-03-08T08:33:23Z + positive regulation of glucocorticoid mediated signalling + up regulation of glucocorticoid mediated signaling pathway + up regulation of glucocorticoid mediated signalling + up-regulation of glucocorticoid mediated signaling pathway + up-regulation of glucocorticoid mediated signalling + upregulation of glucocorticoid mediated signaling pathway + upregulation of glucocorticoid mediated signalling + activation of glucocorticoid mediated signaling pathway + activation of glucocorticoid mediated signalling + biological_process + GO:1900171 + positive regulation of glucocorticoid mediated signaling pathway + + + + + Any process that activates or increases the frequency, rate or extent of glucocorticoid mediated signaling pathway. + GOC:TermGenie + + + + + positive regulation of glucocorticoid mediated signalling + GOC:TermGenie + + + + + up regulation of glucocorticoid mediated signaling pathway + GOC:TermGenie + + + + + up regulation of glucocorticoid mediated signalling + GOC:TermGenie + + + + + up-regulation of glucocorticoid mediated signaling pathway + GOC:TermGenie + + + + + up-regulation of glucocorticoid mediated signalling + GOC:TermGenie + + + + + upregulation of glucocorticoid mediated signaling pathway + GOC:TermGenie + + + + + upregulation of glucocorticoid mediated signalling + GOC:TermGenie + + + + + activation of glucocorticoid mediated signaling pathway + GOC:TermGenie + + + + + activation of glucocorticoid mediated signalling + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of protein localization to nucleus. + bf + 2012-03-12T01:23:44Z + regulation of protein localisation to nucleus + regulation of protein localization in cell nucleus + regulation of protein localization in nucleus + biological_process + GO:1900180 + regulation of protein localization to nucleus + + + + + Any process that modulates the frequency, rate or extent of protein localization to nucleus. + GOC:TermGenie + + + + + regulation of protein localisation to nucleus + GOC:TermGenie + + + + + regulation of protein localization in cell nucleus + GOC:TermGenie + + + + + regulation of protein localization in nucleus + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleus. + bf + 2012-03-12T01:23:48Z + down regulation of protein localisation to nucleus + down regulation of protein localization in cell nucleus + down regulation of protein localization in nucleus + down regulation of protein localization to nucleus + down-regulation of protein localisation to nucleus + down-regulation of protein localization in cell nucleus + down-regulation of protein localization in nucleus + down-regulation of protein localization to nucleus + downregulation of protein localisation to nucleus + downregulation of protein localization in cell nucleus + downregulation of protein localization in nucleus + downregulation of protein localization to nucleus + negative regulation of protein localisation to nucleus + negative regulation of protein localization in cell nucleus + negative regulation of protein localization in nucleus + inhibition of protein localisation to nucleus + inhibition of protein localization in cell nucleus + inhibition of protein localization in nucleus + inhibition of protein localization to nucleus + biological_process + GO:1900181 + negative regulation of protein localization to nucleus + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleus. + GOC:TermGenie + + + + + down regulation of protein localisation to nucleus + GOC:TermGenie + + + + + down regulation of protein localization in cell nucleus + GOC:TermGenie + + + + + down regulation of protein localization in nucleus + GOC:TermGenie + + + + + down regulation of protein localization to nucleus + GOC:TermGenie + + + + + down-regulation of protein localisation to nucleus + GOC:TermGenie + + + + + down-regulation of protein localization in cell nucleus + GOC:TermGenie + + + + + down-regulation of protein localization in nucleus + GOC:TermGenie + + + + + down-regulation of protein localization to nucleus + GOC:TermGenie + + + + + downregulation of protein localisation to nucleus + GOC:TermGenie + + + + + downregulation of protein localization in cell nucleus + GOC:TermGenie + + + + + downregulation of protein localization in nucleus + GOC:TermGenie + + + + + downregulation of protein localization to nucleus + GOC:TermGenie + + + + + negative regulation of protein localisation to nucleus + GOC:TermGenie + + + + + negative regulation of protein localization in cell nucleus + GOC:TermGenie + + + + + negative regulation of protein localization in nucleus + GOC:TermGenie + + + + + inhibition of protein localisation to nucleus + GOC:TermGenie + + + + + inhibition of protein localization in cell nucleus + GOC:TermGenie + + + + + inhibition of protein localization in nucleus + GOC:TermGenie + + + + + inhibition of protein localization to nucleus + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of protein localization to nucleus. + bf + 2012-03-12T01:23:52Z + activation of protein localization in nucleus + positive regulation of protein localisation to nucleus + positive regulation of protein localization in cell nucleus + positive regulation of protein localization in nucleus + up regulation of protein localisation to nucleus + up regulation of protein localization in cell nucleus + up regulation of protein localization in nucleus + up regulation of protein localization to nucleus + up-regulation of protein localisation to nucleus + up-regulation of protein localization in cell nucleus + up-regulation of protein localization in nucleus + up-regulation of protein localization to nucleus + upregulation of protein localisation to nucleus + upregulation of protein localization in cell nucleus + upregulation of protein localization in nucleus + upregulation of protein localization to nucleus + activation of protein localisation to nucleus + activation of protein localization in cell nucleus + activation of protein localization to nucleus + biological_process + GO:1900182 + positive regulation of protein localization to nucleus + + + + + Any process that activates or increases the frequency, rate or extent of protein localization to nucleus. + GOC:TermGenie + + + + + activation of protein localization in nucleus + GOC:TermGenie + + + + + positive regulation of protein localisation to nucleus + GOC:TermGenie + + + + + positive regulation of protein localization in cell nucleus + GOC:TermGenie + + + + + positive regulation of protein localization in nucleus + GOC:TermGenie + + + + + up regulation of protein localisation to nucleus + GOC:TermGenie + + + + + up regulation of protein localization in cell nucleus + GOC:TermGenie + + + + + up regulation of protein localization in nucleus + GOC:TermGenie + + + + + up regulation of protein localization to nucleus + GOC:TermGenie + + + + + up-regulation of protein localisation to nucleus + GOC:TermGenie + + + + + up-regulation of protein localization in cell nucleus + GOC:TermGenie + + + + + up-regulation of protein localization in nucleus + GOC:TermGenie + + + + + up-regulation of protein localization to nucleus + GOC:TermGenie + + + + + upregulation of protein localisation to nucleus + GOC:TermGenie + + + + + upregulation of protein localization in cell nucleus + GOC:TermGenie + + + + + upregulation of protein localization in nucleus + GOC:TermGenie + + + + + upregulation of protein localization to nucleus + GOC:TermGenie + + + + + activation of protein localisation to nucleus + GOC:TermGenie + + + + + activation of protein localization in cell nucleus + GOC:TermGenie + + + + + activation of protein localization to nucleus + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of oocyte maturation. + kmv + 2012-03-19T09:41:18Z + biological_process + GO:1900193 + regulation of oocyte maturation + + + + + Any process that modulates the frequency, rate or extent of oocyte maturation. + GOC:TermGenie + GOC:kmv + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of oocyte maturation. + kmv + 2012-03-19T09:41:27Z + down regulation of oocyte maturation + down-regulation of oocyte maturation + downregulation of oocyte maturation + inhibition of oocyte maturation + biological_process + GO:1900194 + negative regulation of oocyte maturation + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of oocyte maturation. + GOC:TermGenie + GOC:kmv + + + + + down regulation of oocyte maturation + GOC:TermGenie + + + + + down-regulation of oocyte maturation + GOC:TermGenie + + + + + downregulation of oocyte maturation + GOC:TermGenie + + + + + inhibition of oocyte maturation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of oocyte maturation. + kmv + 2012-03-19T09:41:35Z + up regulation of oocyte maturation + up-regulation of oocyte maturation + upregulation of oocyte maturation + activation of oocyte maturation + biological_process + GO:1900195 + positive regulation of oocyte maturation + + + + + Any process that activates or increases the frequency, rate or extent of oocyte maturation. + GOC:TermGenie + GOC:kmv + + + + + up regulation of oocyte maturation + GOC:TermGenie + + + + + up-regulation of oocyte maturation + GOC:TermGenie + + + + + upregulation of oocyte maturation + GOC:TermGenie + + + + + activation of oocyte maturation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of pronephric nephron tubule development. + bf + 2012-03-22T09:23:13Z + biological_process + GO:1900206 + regulation of pronephric nephron tubule development + + + + + Any process that modulates the frequency, rate or extent of pronephric nephron tubule development. + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of pronephric nephron tubule development. + bf + 2012-03-22T09:23:23Z + down regulation of pronephric nephron tubule development + down-regulation of pronephric nephron tubule development + downregulation of pronephric nephron tubule development + inhibition of pronephric nephron tubule development + biological_process + GO:1900207 + negative regulation of pronephric nephron tubule development + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of pronephric nephron tubule development. + GOC:TermGenie + GOC:bf + PMID:9758706 + + + + + down regulation of pronephric nephron tubule development + GOC:TermGenie + + + + + down-regulation of pronephric nephron tubule development + GOC:TermGenie + + + + + downregulation of pronephric nephron tubule development + GOC:TermGenie + + + + + inhibition of pronephric nephron tubule development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of defense response to insect. + dhl + 2012-04-12T04:44:00Z + down regulation of defense response to insect + down regulation of physiological defense response to insect + down-regulation of defense response to insect + down-regulation of physiological defense response to insect + downregulation of defense response to insect + downregulation of physiological defense response to insect + negative regulation of physiological defense response to insect + inhibition of defense response to insect + inhibition of physiological defense response to insect + biological_process + susceptibility to insect + GO:1900366 + negative regulation of defense response to insect + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of defense response to insect. + GOC:TermGenie + PMID:22474183 + + + + + down regulation of defense response to insect + GOC:TermGenie + + + + + down regulation of physiological defense response to insect + GOC:TermGenie + + + + + down-regulation of defense response to insect + GOC:TermGenie + + + + + down-regulation of physiological defense response to insect + GOC:TermGenie + + + + + downregulation of defense response to insect + GOC:TermGenie + + + + + downregulation of physiological defense response to insect + GOC:TermGenie + + + + + negative regulation of physiological defense response to insect + GOC:TermGenie + + + + + inhibition of defense response to insect + GOC:TermGenie + + + + + inhibition of physiological defense response to insect + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of defense response to insect. + dhl + 2012-04-12T04:44:10Z + positive regulation of physiological defense response to insect + up regulation of defense response to insect + up regulation of physiological defense response to insect + up-regulation of defense response to insect + up-regulation of physiological defense response to insect + upregulation of defense response to insect + upregulation of physiological defense response to insect + activation of defense response to insect + activation of physiological defense response to insect + biological_process + GO:1900367 + positive regulation of defense response to insect + + + + + Any process that activates or increases the frequency, rate or extent of defense response to insect. + GOC:TermGenie + PMID:22474183 + + + + + positive regulation of physiological defense response to insect + GOC:TermGenie + + + + + up regulation of defense response to insect + GOC:TermGenie + + + + + up regulation of physiological defense response to insect + GOC:TermGenie + + + + + up-regulation of defense response to insect + GOC:TermGenie + + + + + up-regulation of physiological defense response to insect + GOC:TermGenie + + + + + upregulation of defense response to insect + GOC:TermGenie + + + + + upregulation of physiological defense response to insect + GOC:TermGenie + + + + + activation of defense response to insect + GOC:TermGenie + + + + + activation of physiological defense response to insect + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of secondary metabolite biosynthetic process. + di + 2012-04-17T01:55:23Z + regulation of secondary metabolite biosynthesis + biological_process + GO:1900376 + regulation of secondary metabolite biosynthetic process + + + + + Any process that modulates the frequency, rate or extent of secondary metabolite biosynthetic process. + GOC:TermGenie + GOC:di + + + + + regulation of secondary metabolite biosynthesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of secondary metabolite biosynthetic process. + di + 2012-04-17T01:55:32Z + down regulation of secondary metabolite biosynthesis + down regulation of secondary metabolite biosynthetic process + down-regulation of secondary metabolite biosynthesis + down-regulation of secondary metabolite biosynthetic process + downregulation of secondary metabolite biosynthesis + downregulation of secondary metabolite biosynthetic process + inhibition of secondary metabolite biosynthesis + negative regulation of secondary metabolite biosynthesis + inhibition of secondary metabolite biosynthetic process + biological_process + GO:1900377 + negative regulation of secondary metabolite biosynthetic process + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of secondary metabolite biosynthetic process. + GOC:TermGenie + GOC:di + + + + + down regulation of secondary metabolite biosynthesis + GOC:TermGenie + + + + + down regulation of secondary metabolite biosynthetic process + GOC:TermGenie + + + + + down-regulation of secondary metabolite biosynthesis + GOC:TermGenie + + + + + down-regulation of secondary metabolite biosynthetic process + GOC:TermGenie + + + + + downregulation of secondary metabolite biosynthesis + GOC:TermGenie + + + + + downregulation of secondary metabolite biosynthetic process + GOC:TermGenie + + + + + inhibition of secondary metabolite biosynthesis + GOC:TermGenie + + + + + negative regulation of secondary metabolite biosynthesis + GOC:TermGenie + + + + + inhibition of secondary metabolite biosynthetic process + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of secondary metabolite biosynthetic process. + di + 2012-04-17T01:55:41Z + activation of secondary metabolite biosynthesis + positive regulation of secondary metabolite biosynthesis + up regulation of secondary metabolite biosynthesis + up regulation of secondary metabolite biosynthetic process + up-regulation of secondary metabolite biosynthesis + up-regulation of secondary metabolite biosynthetic process + upregulation of secondary metabolite biosynthesis + upregulation of secondary metabolite biosynthetic process + activation of secondary metabolite biosynthetic process + biological_process + GO:1900378 + positive regulation of secondary metabolite biosynthetic process + + + + + Any process that activates or increases the frequency, rate or extent of secondary metabolite biosynthetic process. + GOC:TermGenie + GOC:di + + + + + activation of secondary metabolite biosynthesis + GOC:TermGenie + + + + + positive regulation of secondary metabolite biosynthesis + GOC:TermGenie + + + + + up regulation of secondary metabolite biosynthesis + GOC:TermGenie + + + + + up regulation of secondary metabolite biosynthetic process + GOC:TermGenie + + + + + up-regulation of secondary metabolite biosynthesis + GOC:TermGenie + + + + + up-regulation of secondary metabolite biosynthetic process + GOC:TermGenie + + + + + upregulation of secondary metabolite biosynthesis + GOC:TermGenie + + + + + upregulation of secondary metabolite biosynthetic process + GOC:TermGenie + + + + + activation of secondary metabolite biosynthetic process + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of defense response to bacterium. + dhl + 2012-04-24T10:12:43Z + GO:1902477 + regulation of defence response to bacteria + regulation of defence response to bacterium + regulation of defense response to bacteria + regulation of defence response to bacterium, incompatible interaction + regulation of defence response to pathogenic bacteria, incompatible interaction + regulation of defence response to pathogenic bacterium, incompatible interaction + regulation of defense response to bacterium, incompatible interaction + regulation of resistance response to pathogenic bacteria + regulation of resistance response to pathogenic bacterium + biological_process + regulation of antibacterial peptide activity + GO:1900424 + regulation of defense response to bacterium + + + + + Any process that modulates the frequency, rate or extent of defense response to bacterium. + GOC:TermGenie + PMID:22346749 + + + + + regulation of defence response to bacteria + GOC:TermGenie + + + + + regulation of defence response to bacterium + GOC:TermGenie + + + + + regulation of defense response to bacteria + GOC:TermGenie + + + + + regulation of defence response to bacterium, incompatible interaction + GOC:TermGenie + + + + + regulation of defence response to pathogenic bacteria, incompatible interaction + GOC:TermGenie + + + + + regulation of defence response to pathogenic bacterium, incompatible interaction + GOC:TermGenie + + + + + regulation of resistance response to pathogenic bacteria + GOC:TermGenie + + + + + regulation of resistance response to pathogenic bacterium + GOC:TermGenie + + + + + regulation of antibacterial peptide activity + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of defense response to bacterium. + dhl + 2012-04-24T10:12:54Z + GO:1902478 + down regulation of defence response to bacteria + down regulation of defence response to bacterium + down regulation of defense response to bacteria + down regulation of defense response to bacterium + down-regulation of defence response to bacteria + down-regulation of defence response to bacterium + down-regulation of defense response to bacteria + down-regulation of defense response to bacterium + downregulation of defence response to bacteria + downregulation of defence response to bacterium + downregulation of defense response to bacteria + downregulation of defense response to bacterium + inhibition of defence response to bacteria + inhibition of defence response to bacterium + inhibition of defense response to bacteria + negative regulation of defence response to bacteria + negative regulation of defence response to bacterium + negative regulation of defense response to bacteria + inhibition of defence response to pathogenic bacteria, incompatible interaction + inhibition of defence response to pathogenic bacterium, incompatible interaction + inhibition of defense response to bacterium + inhibition of defense response to bacterium, incompatible interaction + inhibition of resistance response to pathogenic bacteria + inhibition of resistance response to pathogenic bacterium + inhibition of response to pathogenic bacteria (incompatible interaction) + inhibition of response to pathogenic bacterium (incompatible interaction) + negative regulation of defense response to bacterium, incompatible interaction + biological_process + down regulation of antibacterial peptide activity + down-regulation of antibacterial peptide activity + downregulation of antibacterial peptide activity + inhibition of antibacterial peptide activity + negative regulation of antibacterial peptide activity + GO:1900425 + negative regulation of defense response to bacterium + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of defense response to bacterium. + GOC:TermGenie + PMID:22346749 + + + + + down regulation of defence response to bacteria + GOC:TermGenie + + + + + down regulation of defence response to bacterium + GOC:TermGenie + + + + + down regulation of defense response to bacteria + GOC:TermGenie + + + + + down regulation of defense response to bacterium + GOC:TermGenie + + + + + down-regulation of defence response to bacteria + GOC:TermGenie + + + + + down-regulation of defence response to bacterium + GOC:TermGenie + + + + + down-regulation of defense response to bacteria + GOC:TermGenie + + + + + down-regulation of defense response to bacterium + GOC:TermGenie + + + + + downregulation of defence response to bacteria + GOC:TermGenie + + + + + downregulation of defence response to bacterium + GOC:TermGenie + + + + + downregulation of defense response to bacteria + GOC:TermGenie + + + + + downregulation of defense response to bacterium + GOC:TermGenie + + + + + inhibition of defence response to bacteria + GOC:TermGenie + + + + + inhibition of defence response to bacterium + GOC:TermGenie + + + + + inhibition of defense response to bacteria + GOC:TermGenie + + + + + negative regulation of defence response to bacteria + GOC:TermGenie + + + + + negative regulation of defence response to bacterium + GOC:TermGenie + + + + + negative regulation of defense response to bacteria + GOC:TermGenie + + + + + inhibition of defence response to pathogenic bacteria, incompatible interaction + GOC:TermGenie + + + + + inhibition of defence response to pathogenic bacterium, incompatible interaction + GOC:TermGenie + + + + + inhibition of defense response to bacterium + GOC:TermGenie + + + + + inhibition of defense response to bacterium, incompatible interaction + GOC:TermGenie + + + + + inhibition of resistance response to pathogenic bacteria + GOC:TermGenie + + + + + inhibition of resistance response to pathogenic bacterium + GOC:TermGenie + + + + + inhibition of response to pathogenic bacteria (incompatible interaction) + GOC:TermGenie + + + + + inhibition of response to pathogenic bacterium (incompatible interaction) + GOC:TermGenie + + + + + down regulation of antibacterial peptide activity + GOC:TermGenie + + + + + down-regulation of antibacterial peptide activity + GOC:TermGenie + + + + + downregulation of antibacterial peptide activity + GOC:TermGenie + + + + + inhibition of antibacterial peptide activity + GOC:TermGenie + + + + + negative regulation of antibacterial peptide activity + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of defense response to bacterium. + dhl + 2012-04-24T10:13:13Z + GO:1902479 + activation of defence response to bacteria + activation of defence response to bacterium + activation of defense response to bacteria + positive regulation of defence response to bacteria + positive regulation of defence response to bacterium + positive regulation of defense response to bacteria + up regulation of defence response to bacteria + up regulation of defence response to bacterium + up regulation of defense response to bacteria + up regulation of defense response to bacterium + up-regulation of defence response to bacteria + up-regulation of defence response to bacterium + up-regulation of defense response to bacteria + up-regulation of defense response to bacterium + upregulation of defence response to bacteria + upregulation of defence response to bacterium + upregulation of defense response to bacteria + upregulation of defense response to bacterium + activation of defense response to bacterium + activation of resistance response to pathogenic bacteria + activation of resistance response to pathogenic bacterium + positive regulation of defense response to bacterium, incompatible interaction + biological_process + activation of antibacterial peptide activity + positive regulation of antibacterial peptide activity + up regulation of antibacterial peptide activity + up-regulation of antibacterial peptide activity + upregulation of antibacterial peptide activity + GO:1900426 + positive regulation of defense response to bacterium + + + + + Any process that activates or increases the frequency, rate or extent of defense response to bacterium. + GOC:TermGenie + PMID:22346749 + + + + + activation of defence response to bacteria + GOC:TermGenie + + + + + activation of defence response to bacterium + GOC:TermGenie + + + + + activation of defense response to bacteria + GOC:TermGenie + + + + + positive regulation of defence response to bacteria + GOC:TermGenie + + + + + positive regulation of defence response to bacterium + GOC:TermGenie + + + + + positive regulation of defense response to bacteria + GOC:TermGenie + + + + + up regulation of defence response to bacteria + GOC:TermGenie + + + + + up regulation of defence response to bacterium + GOC:TermGenie + + + + + up regulation of defense response to bacteria + GOC:TermGenie + + + + + up regulation of defense response to bacterium + GOC:TermGenie + + + + + up-regulation of defence response to bacteria + GOC:TermGenie + + + + + up-regulation of defence response to bacterium + GOC:TermGenie + + + + + up-regulation of defense response to bacteria + GOC:TermGenie + + + + + up-regulation of defense response to bacterium + GOC:TermGenie + + + + + upregulation of defence response to bacteria + GOC:TermGenie + + + + + upregulation of defence response to bacterium + GOC:TermGenie + + + + + upregulation of defense response to bacteria + GOC:TermGenie + + + + + upregulation of defense response to bacterium + GOC:TermGenie + + + + + activation of defense response to bacterium + GOC:TermGenie + + + + + activation of resistance response to pathogenic bacteria + GOC:TermGenie + + + + + activation of resistance response to pathogenic bacterium + GOC:TermGenie + + + + + activation of antibacterial peptide activity + GOC:TermGenie + + + + + positive regulation of antibacterial peptide activity + GOC:TermGenie + + + + + up regulation of antibacterial peptide activity + GOC:TermGenie + + + + + up-regulation of antibacterial peptide activity + GOC:TermGenie + + + + + upregulation of antibacterial peptide activity + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of glutamate receptor signaling pathway. + rl + 2012-04-27T03:45:43Z + regulation of glutamate signaling pathway + regulation of glutamate signalling pathway + biological_process + GO:1900449 + regulation of glutamate receptor signaling pathway + + + + + Any process that modulates the frequency, rate or extent of glutamate receptor signaling pathway. + GOC:BHF + GOC:TermGenie + + + + + regulation of glutamate signaling pathway + GOC:TermGenie + + + + + regulation of glutamate signalling pathway + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of glutamate receptor signaling pathway. + rl + 2012-04-27T03:45:53Z + down regulation of glutamate receptor signaling pathway + down regulation of glutamate signaling pathway + down regulation of glutamate signalling pathway + down-regulation of glutamate receptor signaling pathway + down-regulation of glutamate signaling pathway + down-regulation of glutamate signalling pathway + downregulation of glutamate receptor signaling pathway + downregulation of glutamate signaling pathway + downregulation of glutamate signalling pathway + inhibition of glutamate signaling pathway + inhibition of glutamate signalling pathway + negative regulation of glutamate signaling pathway + negative regulation of glutamate signalling pathway + inhibition of glutamate receptor signaling pathway + biological_process + GO:1900450 + negative regulation of glutamate receptor signaling pathway + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of glutamate receptor signaling pathway. + GOC:BHF + GOC:TermGenie + + + + + down regulation of glutamate receptor signaling pathway + GOC:TermGenie + + + + + down regulation of glutamate signaling pathway + GOC:TermGenie + + + + + down regulation of glutamate signalling pathway + GOC:TermGenie + + + + + down-regulation of glutamate receptor signaling pathway + GOC:TermGenie + + + + + down-regulation of glutamate signaling pathway + GOC:TermGenie + + + + + down-regulation of glutamate signalling pathway + GOC:TermGenie + + + + + downregulation of glutamate receptor signaling pathway + GOC:TermGenie + + + + + downregulation of glutamate signaling pathway + GOC:TermGenie + + + + + downregulation of glutamate signalling pathway + GOC:TermGenie + + + + + inhibition of glutamate signaling pathway + GOC:TermGenie + + + + + inhibition of glutamate signalling pathway + GOC:TermGenie + + + + + negative regulation of glutamate signaling pathway + GOC:TermGenie + + + + + negative regulation of glutamate signalling pathway + GOC:TermGenie + + + + + inhibition of glutamate receptor signaling pathway + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of glutamate receptor signaling pathway. + rl + 2012-04-27T03:46:03Z + activation of glutamate signaling pathway + activation of glutamate signalling pathway + positive regulation of glutamate signaling pathway + positive regulation of glutamate signalling pathway + up regulation of glutamate receptor signaling pathway + up regulation of glutamate signaling pathway + up regulation of glutamate signalling pathway + up-regulation of glutamate receptor signaling pathway + up-regulation of glutamate signaling pathway + up-regulation of glutamate signalling pathway + upregulation of glutamate receptor signaling pathway + upregulation of glutamate signaling pathway + upregulation of glutamate signalling pathway + activation of glutamate receptor signaling pathway + biological_process + GO:1900451 + positive regulation of glutamate receptor signaling pathway + + + + + Any process that activates or increases the frequency, rate or extent of glutamate receptor signaling pathway. + GOC:BHF + GOC:TermGenie + + + + + activation of glutamate signaling pathway + GOC:TermGenie + + + + + activation of glutamate signalling pathway + GOC:TermGenie + + + + + positive regulation of glutamate signaling pathway + GOC:TermGenie + + + + + positive regulation of glutamate signalling pathway + GOC:TermGenie + + + + + up regulation of glutamate receptor signaling pathway + GOC:TermGenie + + + + + up regulation of glutamate signaling pathway + GOC:TermGenie + + + + + up regulation of glutamate signalling pathway + GOC:TermGenie + + + + + up-regulation of glutamate receptor signaling pathway + GOC:TermGenie + + + + + up-regulation of glutamate signaling pathway + GOC:TermGenie + + + + + up-regulation of glutamate signalling pathway + GOC:TermGenie + + + + + upregulation of glutamate receptor signaling pathway + GOC:TermGenie + + + + + upregulation of glutamate signaling pathway + GOC:TermGenie + + + + + upregulation of glutamate signalling pathway + GOC:TermGenie + + + + + activation of glutamate receptor signaling pathway + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways involving carbohydrate derivative. + bf + 2012-07-12T04:05:09Z + carbohydrate derivative metabolism + biological_process + GO:1901135 + + + + + carbohydrate derivative metabolic process + + + + + The chemical reactions and pathways involving carbohydrate derivative. + GOC:TermGenie + + + + + carbohydrate derivative metabolism + GOC:TermGenie + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of carbohydrate derivative. + bf + 2012-07-12T04:05:31Z + carbohydrate derivative breakdown + carbohydrate derivative catabolism + carbohydrate derivative degradation + biological_process + GO:1901136 + carbohydrate derivative catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of carbohydrate derivative. + GOC:TermGenie + + + + + carbohydrate derivative breakdown + GOC:TermGenie + + + + + carbohydrate derivative catabolism + GOC:TermGenie + + + + + carbohydrate derivative degradation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of carbohydrate derivative. + bf + 2012-07-12T04:05:39Z + carbohydrate derivative anabolism + carbohydrate derivative biosynthesis + carbohydrate derivative formation + carbohydrate derivative synthesis + biological_process + GO:1901137 + carbohydrate derivative biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of carbohydrate derivative. + GOC:TermGenie + + + + + carbohydrate derivative anabolism + GOC:TermGenie + + + + + carbohydrate derivative biosynthesis + GOC:TermGenie + + + + + carbohydrate derivative formation + GOC:TermGenie + + + + + carbohydrate derivative synthesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways involving insulin. + + + pm + 2012-07-13T12:32:40Z + insulin metabolism + biological_process + GO:1901142 + insulin metabolic process + + + + + The chemical reactions and pathways involving insulin. + GOC:TermGenie + + + + + insulin metabolism + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of insulin. + pm + 2012-07-13T12:33:03Z + insulin breakdown + insulin catabolism + insulin degradation + biological_process + GO:1901143 + insulin catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of insulin. + GOC:TermGenie + + + + + insulin breakdown + GOC:TermGenie + + + + + insulin catabolism + GOC:TermGenie + + + + + insulin degradation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any gene expression that is involved in extracellular matrix organization. Gene expression includes both transcription to produce an RNA transcript, and the translation of that mRNA into protein. Protein maturation is included in gene expression when required to form an active form of a product from an inactive precursor form. + bf + 2012-07-16T03:29:30Z + expression of extracellular matrix proteins + biological_process + extracellular matrix protein production + GO:1901148 + gene expression involved in extracellular matrix organization + + + + + Any gene expression that is involved in extracellular matrix organization. Gene expression includes both transcription to produce an RNA transcript, and the translation of that mRNA into protein. Protein maturation is included in gene expression when required to form an active form of a product from an inactive precursor form. + GOC:TermGenie + GOC:pg + PMID:18668558 + + + + + expression of extracellular matrix proteins + GOC:bf + + + + + extracellular matrix protein production + GOC:pg + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways involving primary amino compound. + bf + 2012-07-18T04:44:39Z + primary amino compound metabolism + biological_process + GO:1901160 + primary amino compound metabolic process + + + + + The chemical reactions and pathways involving primary amino compound. + GOC:TermGenie + + + + + primary amino compound metabolism + GOC:TermGenie + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of primary amino compound. + bf + 2012-07-18T04:45:06Z + primary amino compound breakdown + primary amino compound catabolism + primary amino compound degradation + biological_process + GO:1901161 + primary amino compound catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of primary amino compound. + GOC:TermGenie + + + + + primary amino compound breakdown + GOC:TermGenie + + + + + primary amino compound catabolism + GOC:TermGenie + + + + + primary amino compound degradation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of primary amino compound. + bf + 2012-07-18T04:45:14Z + primary amino compound anabolism + primary amino compound biosynthesis + primary amino compound formation + primary amino compound synthesis + biological_process + GO:1901162 + primary amino compound biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of primary amino compound. + GOC:TermGenie + + + + + primary amino compound anabolism + GOC:TermGenie + + + + + primary amino compound biosynthesis + GOC:TermGenie + + + + + primary amino compound formation + GOC:TermGenie + + + + + primary amino compound synthesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of trophoblast cell migration. + vk + 2012-07-19T07:53:06Z + biological_process + GO:1901163 + regulation of trophoblast cell migration + + + + + Any process that modulates the frequency, rate or extent of trophoblast cell migration. + GOC:BHF + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of trophoblast cell migration. + vk + 2012-07-19T07:53:28Z + down regulation of trophoblast cell migration + down-regulation of trophoblast cell migration + downregulation of trophoblast cell migration + inhibition of trophoblast cell migration + biological_process + GO:1901164 + negative regulation of trophoblast cell migration + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of trophoblast cell migration. + GOC:BHF + GOC:TermGenie + + + + + down regulation of trophoblast cell migration + GOC:TermGenie + + + + + down-regulation of trophoblast cell migration + GOC:TermGenie + + + + + downregulation of trophoblast cell migration + GOC:TermGenie + + + + + inhibition of trophoblast cell migration + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of trophoblast cell migration. + vk + 2012-07-19T07:53:35Z + up regulation of trophoblast cell migration + up-regulation of trophoblast cell migration + upregulation of trophoblast cell migration + activation of trophoblast cell migration + biological_process + GO:1901165 + positive regulation of trophoblast cell migration + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that activates or increases the frequency, rate or extent of trophoblast cell migration. + GOC:BHF + GOC:TermGenie + + + + + up regulation of trophoblast cell migration + GOC:TermGenie + + + + + up-regulation of trophoblast cell migration + GOC:TermGenie + + + + + upregulation of trophoblast cell migration + GOC:TermGenie + + + + + activation of trophoblast cell migration + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any neural crest cell migration that is involved in autonomic nervous system development. + vk + 2012-07-19T08:39:56Z + biological_process + GO:1901166 + neural crest cell migration involved in autonomic nervous system development + + + + + Any neural crest cell migration that is involved in autonomic nervous system development. + GOC:BHF + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of extracellular matrix assembly. + rl + 2012-07-27T04:04:00Z + biological_process + GO:1901201 + regulation of extracellular matrix assembly + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate or extent of extracellular matrix assembly. + GOC:BHF + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix assembly. + rl + 2012-07-27T04:04:24Z + down regulation of extracellular matrix assembly + down-regulation of extracellular matrix assembly + downregulation of extracellular matrix assembly + inhibition of extracellular matrix assembly + biological_process + GO:1901202 + negative regulation of extracellular matrix assembly + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix assembly. + GOC:BHF + GOC:TermGenie + + + + + down regulation of extracellular matrix assembly + GOC:TermGenie + + + + + down-regulation of extracellular matrix assembly + GOC:TermGenie + + + + + downregulation of extracellular matrix assembly + GOC:TermGenie + + + + + inhibition of extracellular matrix assembly + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of extracellular matrix assembly. + rl + 2012-07-27T04:04:32Z + up regulation of extracellular matrix assembly + up-regulation of extracellular matrix assembly + upregulation of extracellular matrix assembly + activation of extracellular matrix assembly + biological_process + GO:1901203 + positive regulation of extracellular matrix assembly + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that activates or increases the frequency, rate or extent of extracellular matrix assembly. + GOC:BHF + GOC:TermGenie + + + + + up regulation of extracellular matrix assembly + GOC:TermGenie + + + + + up-regulation of extracellular matrix assembly + GOC:TermGenie + + + + + upregulation of extracellular matrix assembly + GOC:TermGenie + + + + + activation of extracellular matrix assembly + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of cardiac chamber formation. + rl + 2012-07-31T07:18:35Z + regulation of heart chamber formation + biological_process + GO:1901210 + regulation of cardiac chamber formation + + + + + Any process that modulates the frequency, rate or extent of cardiac chamber formation. + GOC:BHF + GOC:TermGenie + + + + + regulation of heart chamber formation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber formation. + rl + 2012-07-31T07:18:57Z + down regulation of cardiac chamber formation + down regulation of heart chamber formation + down-regulation of cardiac chamber formation + down-regulation of heart chamber formation + downregulation of cardiac chamber formation + downregulation of heart chamber formation + inhibition of heart chamber formation + negative regulation of heart chamber formation + inhibition of cardiac chamber formation + biological_process + GO:1901211 + negative regulation of cardiac chamber formation + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber formation. + GOC:BHF + GOC:TermGenie + + + + + down regulation of cardiac chamber formation + GOC:TermGenie + + + + + down regulation of heart chamber formation + GOC:TermGenie + + + + + down-regulation of cardiac chamber formation + GOC:TermGenie + + + + + down-regulation of heart chamber formation + GOC:TermGenie + + + + + downregulation of cardiac chamber formation + GOC:TermGenie + + + + + downregulation of heart chamber formation + GOC:TermGenie + + + + + inhibition of heart chamber formation + GOC:TermGenie + + + + + negative regulation of heart chamber formation + GOC:TermGenie + + + + + inhibition of cardiac chamber formation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of cardiac chamber formation. + rl + 2012-07-31T07:19:05Z + activation of heart chamber formation + positive regulation of heart chamber formation + up regulation of cardiac chamber formation + up regulation of heart chamber formation + up-regulation of cardiac chamber formation + up-regulation of heart chamber formation + upregulation of cardiac chamber formation + upregulation of heart chamber formation + activation of cardiac chamber formation + biological_process + GO:1901212 + positive regulation of cardiac chamber formation + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that activates or increases the frequency, rate or extent of cardiac chamber formation. + GOC:BHF + GOC:TermGenie + + + + + activation of heart chamber formation + GOC:TermGenie + + + + + positive regulation of heart chamber formation + GOC:TermGenie + + + + + up regulation of cardiac chamber formation + GOC:TermGenie + + + + + up regulation of heart chamber formation + GOC:TermGenie + + + + + up-regulation of cardiac chamber formation + GOC:TermGenie + + + + + up-regulation of heart chamber formation + GOC:TermGenie + + + + + upregulation of cardiac chamber formation + GOC:TermGenie + + + + + upregulation of heart chamber formation + GOC:TermGenie + + + + + activation of cardiac chamber formation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of cardiac chamber morphogenesis. + rl + 2012-08-06T17:59:11Z + regulation of heart chamber morphogenesis + biological_process + GO:1901219 + regulation of cardiac chamber morphogenesis + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate or extent of cardiac chamber morphogenesis. + GOC:BHF + GOC:TermGenie + + + + + regulation of heart chamber morphogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber morphogenesis. + rl + 2012-08-06T17:59:34Z + down regulation of cardiac chamber morphogenesis + down regulation of heart chamber morphogenesis + down-regulation of cardiac chamber morphogenesis + down-regulation of heart chamber morphogenesis + downregulation of cardiac chamber morphogenesis + downregulation of heart chamber morphogenesis + negative regulation of heart chamber morphogenesis + inhibition of cardiac chamber morphogenesis + inhibition of heart chamber morphogenesis + biological_process + GO:1901220 + negative regulation of cardiac chamber morphogenesis + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber morphogenesis. + GOC:BHF + GOC:TermGenie + + + + + down regulation of cardiac chamber morphogenesis + GOC:TermGenie + + + + + down regulation of heart chamber morphogenesis + GOC:TermGenie + + + + + down-regulation of cardiac chamber morphogenesis + GOC:TermGenie + + + + + down-regulation of heart chamber morphogenesis + GOC:TermGenie + + + + + downregulation of cardiac chamber morphogenesis + GOC:TermGenie + + + + + downregulation of heart chamber morphogenesis + GOC:TermGenie + + + + + negative regulation of heart chamber morphogenesis + GOC:TermGenie + + + + + inhibition of cardiac chamber morphogenesis + GOC:TermGenie + + + + + inhibition of heart chamber morphogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of cardiac chamber morphogenesis. + rl + 2012-08-06T17:59:42Z + positive regulation of heart chamber morphogenesis + up regulation of cardiac chamber morphogenesis + up regulation of heart chamber morphogenesis + up-regulation of cardiac chamber morphogenesis + up-regulation of heart chamber morphogenesis + upregulation of cardiac chamber morphogenesis + upregulation of heart chamber morphogenesis + activation of cardiac chamber morphogenesis + activation of heart chamber morphogenesis + biological_process + GO:1901221 + positive regulation of cardiac chamber morphogenesis + + + + + Any process that activates or increases the frequency, rate or extent of cardiac chamber morphogenesis. + GOC:BHF + GOC:TermGenie + + + + + positive regulation of heart chamber morphogenesis + GOC:TermGenie + + + + + up regulation of cardiac chamber morphogenesis + GOC:TermGenie + + + + + up regulation of heart chamber morphogenesis + GOC:TermGenie + + + + + up-regulation of cardiac chamber morphogenesis + GOC:TermGenie + + + + + up-regulation of heart chamber morphogenesis + GOC:TermGenie + + + + + upregulation of cardiac chamber morphogenesis + GOC:TermGenie + + + + + upregulation of heart chamber morphogenesis + GOC:TermGenie + + + + + activation of cardiac chamber morphogenesis + GOC:TermGenie + + + + + activation of heart chamber morphogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + The directed movement of a carbohydrate derivative into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + bf + 2012-08-16T14:51:22Z + biological_process + GO:1901264 + carbohydrate derivative transport + + + + + The directed movement of a carbohydrate derivative into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. + GOC:TermGenie + GOC:bf + GOC:jl + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of flagellated sperm motility. + hjd + 2012-08-22T20:50:14Z + regulation of sperm motility + regulation of sperm movement + biological_process + GO:1901317 + regulation of flagellated sperm motility + + + + + Any process that modulates the frequency, rate or extent of flagellated sperm motility. + GOC:TermGenie + GOC:cilia + GOC:krc + + + + + regulation of sperm movement + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of flagellated sperm motility. + hjd + 2012-08-22T20:50:35Z + down regulation of sperm motility + down regulation of sperm movement + down-regulation of sperm motility + down-regulation of sperm movement + downregulation of sperm motility + downregulation of sperm movement + inhibition of sperm movement + negative regulation of sperm motility + negative regulation of sperm movement + inhibition of sperm motility + biological_process + GO:1901318 + negative regulation of flagellated sperm motility + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of flagellated sperm motility. + GOC:TermGenie + GOC:cilia + GOC:krc + + + + + down regulation of sperm motility + GOC:TermGenie + + + + + down regulation of sperm movement + GOC:TermGenie + + + + + down-regulation of sperm motility + GOC:TermGenie + + + + + down-regulation of sperm movement + GOC:TermGenie + + + + + downregulation of sperm motility + GOC:TermGenie + + + + + downregulation of sperm movement + GOC:TermGenie + + + + + inhibition of sperm movement + GOC:TermGenie + + + + + negative regulation of sperm movement + GOC:TermGenie + + + + + inhibition of sperm motility + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of odontoblast differentiation. + hjd + 2012-08-31T16:50:05Z + biological_process + GO:1901329 + regulation of odontoblast differentiation + + + + + Any process that modulates the frequency, rate or extent of odontoblast differentiation. + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of odontoblast differentiation. + hjd + 2012-08-31T16:50:27Z + down regulation of odontoblast differentiation + down-regulation of odontoblast differentiation + downregulation of odontoblast differentiation + inhibition of odontoblast differentiation + biological_process + GO:1901330 + negative regulation of odontoblast differentiation + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of odontoblast differentiation. + GOC:TermGenie + + + + + down regulation of odontoblast differentiation + GOC:TermGenie + + + + + down-regulation of odontoblast differentiation + GOC:TermGenie + + + + + downregulation of odontoblast differentiation + GOC:TermGenie + + + + + inhibition of odontoblast differentiation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of odontoblast differentiation. + hjd + 2012-08-31T16:50:35Z + up regulation of odontoblast differentiation + up-regulation of odontoblast differentiation + upregulation of odontoblast differentiation + activation of odontoblast differentiation + biological_process + GO:1901331 + positive regulation of odontoblast differentiation + + + + + Any process that activates or increases the frequency, rate or extent of odontoblast differentiation. + GOC:TermGenie + + + + + up regulation of odontoblast differentiation + GOC:TermGenie + + + + + up-regulation of odontoblast differentiation + GOC:TermGenie + + + + + upregulation of odontoblast differentiation + GOC:TermGenie + + + + + activation of odontoblast differentiation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Binding to catecholamine. + bf + 2012-09-03T14:08:44Z + molecular_function + GO:1901338 + catecholamine binding + + + + + Binding to catecholamine. + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of vasculature development. + bf + 2012-09-06T09:16:15Z + biological_process + regulation of vascular system development + GO:1901342 + regulation of vasculature development + + + + + Any process that modulates the frequency, rate or extent of vasculature development. + GOC:TermGenie + + + + + regulation of vascular system development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of vasculature development. + bf + 2012-09-06T09:17:24Z + down regulation of vasculature development + down-regulation of vasculature development + downregulation of vasculature development + inhibition of vasculature development + biological_process + down regulation of vascular system development + down-regulation of vascular system development + downregulation of vascular system development + inhibition of vascular system development + negative regulation of vascular system development + GO:1901343 + negative regulation of vasculature development + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of vasculature development. + GOC:TermGenie + + + + + down regulation of vasculature development + GOC:TermGenie + + + + + down-regulation of vasculature development + GOC:TermGenie + + + + + downregulation of vasculature development + GOC:TermGenie + + + + + inhibition of vasculature development + GOC:TermGenie + + + + + down regulation of vascular system development + GOC:TermGenie + + + + + down-regulation of vascular system development + GOC:TermGenie + + + + + downregulation of vascular system development + GOC:TermGenie + + + + + inhibition of vascular system development + GOC:TermGenie + + + + + negative regulation of vascular system development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways involving organic cyclic compound. + bf + 2012-09-14T09:03:51Z + organic cyclic compound metabolism + biological_process + GO:1901360 + organic cyclic compound metabolic process + + + + + The chemical reactions and pathways involving organic cyclic compound. + GOC:TermGenie + + + + + organic cyclic compound metabolism + GOC:TermGenie + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of organic cyclic compound. + bf + 2012-09-14T09:05:04Z + organic cyclic compound breakdown + organic cyclic compound catabolism + organic cyclic compound degradation + biological_process + GO:1901361 + organic cyclic compound catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of organic cyclic compound. + GOC:TermGenie + + + + + organic cyclic compound breakdown + GOC:TermGenie + + + + + organic cyclic compound catabolism + GOC:TermGenie + + + + + organic cyclic compound degradation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of organic cyclic compound. + bf + 2012-09-14T09:05:22Z + organic cyclic compound anabolism + organic cyclic compound biosynthesis + organic cyclic compound formation + organic cyclic compound synthesis + biological_process + GO:1901362 + organic cyclic compound biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of organic cyclic compound. + GOC:TermGenie + + + + + organic cyclic compound anabolism + GOC:TermGenie + + + + + organic cyclic compound biosynthesis + GOC:TermGenie + + + + + organic cyclic compound formation + GOC:TermGenie + + + + + organic cyclic compound synthesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Binding to heterocyclic compound. + bf + 2012-09-14T13:53:50Z + molecular_function + GO:1901363 + heterocyclic compound binding + + + + + Binding to heterocyclic compound. + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of lymphangiogenesis. + dph + 2012-10-15T13:08:17Z + regulation of lymph vessel formation + biological_process + GO:1901490 + regulation of lymphangiogenesis + + + + + Any process that modulates the frequency, rate or extent of lymphangiogenesis. + GOC:TermGenie + GOC:dph + PMID:20133819 + + + + + regulation of lymph vessel formation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of lymphangiogenesis. + dph + 2012-10-15T13:08:21Z + down regulation of lymph vessel formation + down regulation of lymphangiogenesis + down-regulation of lymph vessel formation + down-regulation of lymphangiogenesis + downregulation of lymph vessel formation + downregulation of lymphangiogenesis + negative regulation of lymph vessel formation + inhibition of lymph vessel formation + inhibition of lymphangiogenesis + biological_process + GO:1901491 + negative regulation of lymphangiogenesis + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of lymphangiogenesis. + GOC:TermGenie + GOC:dph + PMID:20133819 + + + + + down regulation of lymph vessel formation + GOC:TermGenie + + + + + down regulation of lymphangiogenesis + GOC:TermGenie + + + + + down-regulation of lymph vessel formation + GOC:TermGenie + + + + + down-regulation of lymphangiogenesis + GOC:TermGenie + + + + + downregulation of lymph vessel formation + GOC:TermGenie + + + + + downregulation of lymphangiogenesis + GOC:TermGenie + + + + + negative regulation of lymph vessel formation + GOC:TermGenie + + + + + inhibition of lymph vessel formation + GOC:TermGenie + + + + + inhibition of lymphangiogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of lymphangiogenesis. + dph + 2012-10-15T13:08:25Z + positive regulation of lymph vessel formation + up regulation of lymph vessel formation + up regulation of lymphangiogenesis + up-regulation of lymph vessel formation + up-regulation of lymphangiogenesis + upregulation of lymph vessel formation + upregulation of lymphangiogenesis + activation of lymph vessel formation + activation of lymphangiogenesis + biological_process + GO:1901492 + positive regulation of lymphangiogenesis + + + + + Any process that activates or increases the frequency, rate or extent of lymphangiogenesis. + GOC:TermGenie + GOC:dph + PMID:20133819 + + + + + positive regulation of lymph vessel formation + GOC:TermGenie + + + + + up regulation of lymph vessel formation + GOC:TermGenie + + + + + up regulation of lymphangiogenesis + GOC:TermGenie + + + + + up-regulation of lymph vessel formation + GOC:TermGenie + + + + + up-regulation of lymphangiogenesis + GOC:TermGenie + + + + + upregulation of lymph vessel formation + GOC:TermGenie + + + + + upregulation of lymphangiogenesis + GOC:TermGenie + + + + + activation of lymph vessel formation + GOC:TermGenie + + + + + activation of lymphangiogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of endothelial tube morphogenesis. + dph + 2012-10-17T14:30:40Z + biological_process + GO:1901509 + regulation of endothelial tube morphogenesis + + + + + Any process that modulates the frequency, rate or extent of endothelial tube morphogenesis. + GOC:TermGenie + GOC:dph + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of endothelial cell development. + pr + 2012-10-30T12:59:50Z + biological_process + GO:1901550 + regulation of endothelial cell development + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate or extent of endothelial cell development. + GOC:TermGenie + GOC:pr + PMID:19470579 + + + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell development. + pr + 2012-10-30T12:59:54Z + down regulation of endothelial cell development + down-regulation of endothelial cell development + downregulation of endothelial cell development + inhibition of endothelial cell development + biological_process + GO:1901551 + negative regulation of endothelial cell development + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell development. + GOC:TermGenie + GOC:pr + PMID:19470579 + + + + + down regulation of endothelial cell development + GOC:TermGenie + + + + + down-regulation of endothelial cell development + GOC:TermGenie + + + + + downregulation of endothelial cell development + GOC:TermGenie + + + + + inhibition of endothelial cell development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of endothelial cell development. + pr + 2012-10-30T12:59:58Z + up regulation of endothelial cell development + up-regulation of endothelial cell development + upregulation of endothelial cell development + activation of endothelial cell development + biological_process + GO:1901552 + positive regulation of endothelial cell development + + + + + Any process that activates or increases the frequency, rate or extent of endothelial cell development. + GOC:TermGenie + GOC:pr + PMID:19470579 + + + + + up regulation of endothelial cell development + GOC:TermGenie + + + + + up-regulation of endothelial cell development + GOC:TermGenie + + + + + upregulation of endothelial cell development + GOC:TermGenie + + + + + activation of endothelial cell development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways involving organonitrogen compound. + pr + 2012-11-04T15:17:52Z + organonitrogen compound metabolism + biological_process + GO:1901564 + organonitrogen compound metabolic process + + + + + The chemical reactions and pathways involving organonitrogen compound. + GOC:TermGenie + GOC:pr + + + + + organonitrogen compound metabolism + GOC:TermGenie + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of organonitrogen compound. + pr + 2012-11-04T15:17:56Z + organonitrogen compound breakdown + organonitrogen compound catabolism + organonitrogen compound degradation + biological_process + GO:1901565 + organonitrogen compound catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of organonitrogen compound. + GOC:TermGenie + GOC:pr + + + + + organonitrogen compound breakdown + GOC:TermGenie + + + + + organonitrogen compound catabolism + GOC:TermGenie + + + + + organonitrogen compound degradation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of organonitrogen compound. + pr + 2012-11-04T15:18:00Z + organonitrogen compound anabolism + organonitrogen compound biosynthesis + organonitrogen compound formation + organonitrogen compound synthesis + biological_process + GO:1901566 + organonitrogen compound biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of organonitrogen compound. + GOC:TermGenie + GOC:pr + + + + + organonitrogen compound anabolism + GOC:TermGenie + + + + + organonitrogen compound biosynthesis + GOC:TermGenie + + + + + organonitrogen compound formation + GOC:TermGenie + + + + + organonitrogen compound synthesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of an organic substance, any molecular entity containing carbon. + pr + 2012-11-05T11:04:36Z + organic molecular entity breakdown + organic molecular entity catabolic process + organic molecular entity catabolism + organic molecular entity degradation + organic substance breakdown + organic substance catabolism + organic substance degradation + biological_process + GO:1901575 + organic substance catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of an organic substance, any molecular entity containing carbon. + GOC:TermGenie + GOC:pr + + + + + organic molecular entity breakdown + GOC:TermGenie + + + + + organic molecular entity catabolism + GOC:TermGenie + + + + + organic molecular entity degradation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of an organic substance, any molecular entity containing carbon. + pr + 2012-11-05T11:04:40Z + organic molecular entity anabolism + organic molecular entity biosynthesis + organic molecular entity biosynthetic process + organic molecular entity formation + organic molecular entity synthesis + organic substance anabolism + organic substance biosynthesis + organic substance formation + organic substance synthesis + biological_process + GO:1901576 + organic substance biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of an organic substance, any molecular entity containing carbon. + GOC:TermGenie + GOC:pr + + + + + organic molecular entity anabolism + GOC:TermGenie + + + + + organic molecular entity biosynthesis + GOC:TermGenie + + + + + organic molecular entity formation + GOC:TermGenie + + + + + organic molecular entity synthesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Any microtubule in a dendrite, a neuron projection. + pr + 2012-11-07T14:37:30Z + NIF_Subcellular:sao110773650 + microtubule of dendrite + microtubulus of dendrite + cellular_component + GO:1901588 + dendritic microtubule + + + + + Any microtubule in a dendrite, a neuron projection. + GOC:TermGenie + NIF_Subcellular:sao110773650 + + + + + microtubule of dendrite + GOC:TermGenie + + + + + microtubulus of dendrite + GOC:TermGenie + + + + + + + + + + + + + + + + + + + An arrangement of closely apposed microtubules running parallel to each other in the axon hillock and initial segment. + pr + 2012-11-07T15:37:12Z + NIF_Subcellular:sao707332678 + axon microtubule fascicle + microtubule bundle of axon + microtubule fascicle of axon + cellular_component + GO:1901589 + axon microtubule bundle + + + + + An arrangement of closely apposed microtubules running parallel to each other in the axon hillock and initial segment. + GOC:TermGenie + NIF_Subcellular:sao707332678 + + + + + microtubule bundle of axon + GOC:TermGenie + + + + + microtubule fascicle of axon + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways involving an alpha-amino acid. + tb + 2012-11-08T17:39:50Z + alpha-amino acid metabolism + biological_process + GO:1901605 + alpha-amino acid metabolic process + + + + + The chemical reactions and pathways involving an alpha-amino acid. + GOC:TermGenie + + + + + alpha-amino acid metabolism + GOC:TermGenie + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of an alpha-amino acid. + tb + 2012-11-08T17:39:54Z + alpha-amino acid breakdown + alpha-amino acid catabolism + alpha-amino acid degradation + biological_process + GO:1901606 + alpha-amino acid catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of an alpha-amino acid. + GOC:TermGenie + + + + + alpha-amino acid breakdown + GOC:TermGenie + + + + + alpha-amino acid catabolism + GOC:TermGenie + + + + + alpha-amino acid degradation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of an alpha-amino acid. + tb + 2012-11-08T17:39:58Z + alpha-amino acid anabolism + alpha-amino acid biosynthesis + alpha-amino acid formation + alpha-amino acid synthesis + biological_process + GO:1901607 + alpha-amino acid biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of an alpha-amino acid. + GOC:TermGenie + + + + + alpha-amino acid anabolism + GOC:TermGenie + + + + + alpha-amino acid biosynthesis + GOC:TermGenie + + + + + alpha-amino acid formation + GOC:TermGenie + + + + + alpha-amino acid synthesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of vesicle transport along microtubule. + hjd + 2012-11-08T21:49:44Z + regulation of microtubule-based vesicle localization + biological_process + GO:1901608 + regulation of vesicle transport along microtubule + + + + + Any process that modulates the frequency, rate or extent of vesicle transport along microtubule. + GOC:TermGenie + + + + + regulation of microtubule-based vesicle localization + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of vesicle transport along microtubule. + hjd + 2012-11-08T21:49:48Z + down regulation of microtubule-based vesicle localization + down regulation of vesicle transport along microtubule + down-regulation of microtubule-based vesicle localization + down-regulation of vesicle transport along microtubule + downregulation of microtubule-based vesicle localization + downregulation of vesicle transport along microtubule + inhibition of microtubule-based vesicle localization + negative regulation of microtubule-based vesicle localization + inhibition of vesicle transport along microtubule + biological_process + GO:1901609 + negative regulation of vesicle transport along microtubule + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of vesicle transport along microtubule. + GOC:TermGenie + + + + + down regulation of microtubule-based vesicle localization + GOC:TermGenie + + + + + down regulation of vesicle transport along microtubule + GOC:TermGenie + + + + + down-regulation of microtubule-based vesicle localization + GOC:TermGenie + + + + + down-regulation of vesicle transport along microtubule + GOC:TermGenie + + + + + downregulation of microtubule-based vesicle localization + GOC:TermGenie + + + + + downregulation of vesicle transport along microtubule + GOC:TermGenie + + + + + inhibition of microtubule-based vesicle localization + GOC:TermGenie + + + + + negative regulation of microtubule-based vesicle localization + GOC:TermGenie + + + + + inhibition of vesicle transport along microtubule + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of vesicle transport along microtubule. + hjd + 2012-11-08T21:49:53Z + activation of microtubule-based vesicle localization + positive regulation of microtubule-based vesicle localization + up regulation of microtubule-based vesicle localization + up regulation of vesicle transport along microtubule + up-regulation of microtubule-based vesicle localization + up-regulation of vesicle transport along microtubule + upregulation of microtubule-based vesicle localization + upregulation of vesicle transport along microtubule + activation of vesicle transport along microtubule + biological_process + GO:1901610 + positive regulation of vesicle transport along microtubule + + + + + Any process that activates or increases the frequency, rate or extent of vesicle transport along microtubule. + GOC:TermGenie + + + + + activation of microtubule-based vesicle localization + GOC:TermGenie + + + + + positive regulation of microtubule-based vesicle localization + GOC:TermGenie + + + + + up regulation of microtubule-based vesicle localization + GOC:TermGenie + + + + + up regulation of vesicle transport along microtubule + GOC:TermGenie + + + + + up-regulation of microtubule-based vesicle localization + GOC:TermGenie + + + + + up-regulation of vesicle transport along microtubule + GOC:TermGenie + + + + + upregulation of microtubule-based vesicle localization + GOC:TermGenie + + + + + upregulation of vesicle transport along microtubule + GOC:TermGenie + + + + + activation of vesicle transport along microtubule + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways involving organic hydroxy compound. + pr + 2012-11-13T12:54:27Z + organic hydroxy compound metabolism + biological_process + GO:1901615 + organic hydroxy compound metabolic process + + + + + The chemical reactions and pathways involving organic hydroxy compound. + GOC:TermGenie + GOC:pr + + + + + organic hydroxy compound metabolism + GOC:TermGenie + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of organic hydroxy compound. + pr + 2012-11-13T12:54:31Z + organic hydroxy compound breakdown + organic hydroxy compound catabolism + organic hydroxy compound degradation + biological_process + GO:1901616 + organic hydroxy compound catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of organic hydroxy compound. + GOC:TermGenie + GOC:pr + + + + + organic hydroxy compound breakdown + GOC:TermGenie + + + + + organic hydroxy compound catabolism + GOC:TermGenie + + + + + organic hydroxy compound degradation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of organic hydroxy compound. + pr + 2012-11-13T12:54:36Z + organic hydroxy compound anabolism + organic hydroxy compound biosynthesis + organic hydroxy compound formation + organic hydroxy compound synthesis + biological_process + GO:1901617 + organic hydroxy compound biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of organic hydroxy compound. + GOC:TermGenie + GOC:pr + + + + + organic hydroxy compound anabolism + GOC:TermGenie + + + + + organic hydroxy compound biosynthesis + GOC:TermGenie + + + + + organic hydroxy compound formation + GOC:TermGenie + + + + + organic hydroxy compound synthesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus. + pr + 2012-11-20T09:45:15Z + biological_process + GO:1901652 + response to peptide + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus. + GOC:TermGenie + GOC:pr + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus. + pr + 2012-11-20T09:45:19Z + biological_process + GO:1901653 + cellular response to peptide + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus. + GOC:TermGenie + GOC:pr + + + + + + + + + + + + + + + + + + + + A response that results in a state of tolerance to ketone. + pr + 2012-11-20T10:55:47Z + GO:1990369 + process resulting in tolerance to ketone + biological_process + GO:1901654 + response to ketone + + + + + A response that results in a state of tolerance to ketone. + GOC:mengo_curators + PMID:23356676 + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ketone stimulus. + pr + 2012-11-20T10:55:51Z + biological_process + GO:1901655 + cellular response to ketone + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ketone stimulus. + GOC:TermGenie + GOC:pr + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus. + pr + 2012-12-13T15:06:08Z + response to nitrogen molecular entity + biological_process + GO:1901698 + response to nitrogen compound + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus. + GOC:TermGenie + GOC:pr + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus. + pr + 2012-12-13T15:06:13Z + cellular response to nitrogen molecular entity + biological_process + GO:1901699 + cellular response to nitrogen compound + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus. + GOC:TermGenie + GOC:pr + + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus. + pr + 2012-12-13T15:11:37Z + response to oxygen molecular entity + biological_process + GO:1901700 + response to oxygen-containing compound + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus. + GOC:TermGenie + GOC:pr + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus. + pr + 2012-12-13T15:11:42Z + cellular response to oxygen molecular entity + biological_process + GO:1901701 + cellular response to oxygen-containing compound + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus. + GOC:TermGenie + GOC:pr + + + + + + + + + + + + + + + + + + + The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of bone as it progresses from its formation to the mature state. + hjd + 2012-12-14T16:04:16Z + biological_process + GO:1901706 + mesenchymal cell differentiation involved in bone development + + + + + The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of bone as it progresses from its formation to the mature state. + GOC:TermGenie + GOC:hjd + PMID:21571217 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of gamma-aminobutyric acid catabolic process. + mcc + 2012-12-19T16:13:24Z + regulation of 4-aminobutanoate catabolic process + regulation of 4-aminobutanoate catabolism + regulation of 4-aminobutyrate catabolic process + regulation of 4-aminobutyrate catabolism + regulation of GABA catabolic process + regulation of GABA catabolism + regulation of gamma-aminobutyric acid breakdown + regulation of gamma-aminobutyric acid catabolism + regulation of gamma-aminobutyric acid degradation + biological_process + GO:1901715 + regulation of gamma-aminobutyric acid catabolic process + + + + + Any process that modulates the frequency, rate or extent of gamma-aminobutyric acid catabolic process. + GOC:TermGenie + + + + + regulation of 4-aminobutanoate catabolic process + GOC:TermGenie + + + + + regulation of 4-aminobutanoate catabolism + GOC:TermGenie + + + + + regulation of 4-aminobutyrate catabolic process + GOC:TermGenie + + + + + regulation of 4-aminobutyrate catabolism + GOC:TermGenie + + + + + regulation of GABA catabolic process + GOC:TermGenie + + + + + regulation of GABA catabolism + GOC:TermGenie + + + + + regulation of gamma-aminobutyric acid breakdown + GOC:TermGenie + + + + + regulation of gamma-aminobutyric acid catabolism + GOC:TermGenie + + + + + regulation of gamma-aminobutyric acid degradation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of gamma-aminobutyric acid catabolic process. + mcc + 2012-12-19T16:13:31Z + down regulation of 4-aminobutanoate catabolic process + down regulation of 4-aminobutanoate catabolism + down regulation of 4-aminobutyrate catabolic process + down regulation of 4-aminobutyrate catabolism + down regulation of GABA catabolic process + down regulation of GABA catabolism + down regulation of gamma-aminobutyric acid breakdown + down regulation of gamma-aminobutyric acid catabolic process + down regulation of gamma-aminobutyric acid catabolism + down regulation of gamma-aminobutyric acid degradation + down-regulation of 4-aminobutanoate catabolic process + down-regulation of 4-aminobutanoate catabolism + down-regulation of 4-aminobutyrate catabolic process + down-regulation of 4-aminobutyrate catabolism + down-regulation of GABA catabolic process + down-regulation of GABA catabolism + down-regulation of gamma-aminobutyric acid breakdown + down-regulation of gamma-aminobutyric acid catabolic process + down-regulation of gamma-aminobutyric acid catabolism + down-regulation of gamma-aminobutyric acid degradation + downregulation of 4-aminobutanoate catabolic process + downregulation of 4-aminobutanoate catabolism + downregulation of 4-aminobutyrate catabolic process + downregulation of 4-aminobutyrate catabolism + downregulation of GABA catabolic process + downregulation of GABA catabolism + downregulation of gamma-aminobutyric acid breakdown + downregulation of gamma-aminobutyric acid catabolic process + downregulation of gamma-aminobutyric acid catabolism + downregulation of gamma-aminobutyric acid degradation + inhibition of 4-aminobutanoate catabolic process + inhibition of 4-aminobutanoate catabolism + inhibition of 4-aminobutyrate catabolic process + inhibition of 4-aminobutyrate catabolism + inhibition of GABA catabolic process + inhibition of GABA catabolism + inhibition of gamma-aminobutyric acid breakdown + inhibition of gamma-aminobutyric acid catabolism + inhibition of gamma-aminobutyric acid degradation + negative regulation of 4-aminobutanoate catabolic process + negative regulation of 4-aminobutanoate catabolism + negative regulation of 4-aminobutyrate catabolic process + negative regulation of 4-aminobutyrate catabolism + negative regulation of GABA catabolic process + negative regulation of GABA catabolism + negative regulation of gamma-aminobutyric acid breakdown + negative regulation of gamma-aminobutyric acid catabolism + negative regulation of gamma-aminobutyric acid degradation + inhibition of gamma-aminobutyric acid catabolic process + biological_process + GO:1901716 + negative regulation of gamma-aminobutyric acid catabolic process + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of gamma-aminobutyric acid catabolic process. + GOC:TermGenie + + + + + down regulation of 4-aminobutanoate catabolic process + GOC:TermGenie + + + + + down regulation of 4-aminobutanoate catabolism + GOC:TermGenie + + + + + down regulation of 4-aminobutyrate catabolic process + GOC:TermGenie + + + + + down regulation of 4-aminobutyrate catabolism + GOC:TermGenie + + + + + down regulation of GABA catabolic process + GOC:TermGenie + + + + + down regulation of GABA catabolism + GOC:TermGenie + + + + + down regulation of gamma-aminobutyric acid breakdown + GOC:TermGenie + + + + + down regulation of gamma-aminobutyric acid catabolic process + GOC:TermGenie + + + + + down regulation of gamma-aminobutyric acid catabolism + GOC:TermGenie + + + + + down regulation of gamma-aminobutyric acid degradation + GOC:TermGenie + + + + + down-regulation of 4-aminobutanoate catabolic process + GOC:TermGenie + + + + + down-regulation of 4-aminobutanoate catabolism + GOC:TermGenie + + + + + down-regulation of 4-aminobutyrate catabolic process + GOC:TermGenie + + + + + down-regulation of 4-aminobutyrate catabolism + GOC:TermGenie + + + + + down-regulation of GABA catabolic process + GOC:TermGenie + + + + + down-regulation of GABA catabolism + GOC:TermGenie + + + + + down-regulation of gamma-aminobutyric acid breakdown + GOC:TermGenie + + + + + down-regulation of gamma-aminobutyric acid catabolic process + GOC:TermGenie + + + + + down-regulation of gamma-aminobutyric acid catabolism + GOC:TermGenie + + + + + down-regulation of gamma-aminobutyric acid degradation + GOC:TermGenie + + + + + downregulation of 4-aminobutanoate catabolic process + GOC:TermGenie + + + + + downregulation of 4-aminobutanoate catabolism + GOC:TermGenie + + + + + downregulation of 4-aminobutyrate catabolic process + GOC:TermGenie + + + + + downregulation of 4-aminobutyrate catabolism + GOC:TermGenie + + + + + downregulation of GABA catabolic process + GOC:TermGenie + + + + + downregulation of GABA catabolism + GOC:TermGenie + + + + + downregulation of gamma-aminobutyric acid breakdown + GOC:TermGenie + + + + + downregulation of gamma-aminobutyric acid catabolic process + GOC:TermGenie + + + + + downregulation of gamma-aminobutyric acid catabolism + GOC:TermGenie + + + + + downregulation of gamma-aminobutyric acid degradation + GOC:TermGenie + + + + + inhibition of 4-aminobutanoate catabolic process + GOC:TermGenie + + + + + inhibition of 4-aminobutanoate catabolism + GOC:TermGenie + + + + + inhibition of 4-aminobutyrate catabolic process + GOC:TermGenie + + + + + inhibition of 4-aminobutyrate catabolism + GOC:TermGenie + + + + + inhibition of GABA catabolic process + GOC:TermGenie + + + + + inhibition of GABA catabolism + GOC:TermGenie + + + + + inhibition of gamma-aminobutyric acid breakdown + GOC:TermGenie + + + + + inhibition of gamma-aminobutyric acid catabolism + GOC:TermGenie + + + + + inhibition of gamma-aminobutyric acid degradation + GOC:TermGenie + + + + + negative regulation of 4-aminobutanoate catabolic process + GOC:TermGenie + + + + + negative regulation of 4-aminobutanoate catabolism + GOC:TermGenie + + + + + negative regulation of 4-aminobutyrate catabolic process + GOC:TermGenie + + + + + negative regulation of 4-aminobutyrate catabolism + GOC:TermGenie + + + + + negative regulation of GABA catabolic process + GOC:TermGenie + + + + + negative regulation of GABA catabolism + GOC:TermGenie + + + + + negative regulation of gamma-aminobutyric acid breakdown + GOC:TermGenie + + + + + negative regulation of gamma-aminobutyric acid catabolism + GOC:TermGenie + + + + + negative regulation of gamma-aminobutyric acid degradation + GOC:TermGenie + + + + + inhibition of gamma-aminobutyric acid catabolic process + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of gamma-aminobutyric acid catabolic process. + mcc + 2012-12-19T16:13:36Z + activation of 4-aminobutanoate catabolic process + activation of 4-aminobutanoate catabolism + activation of 4-aminobutyrate catabolic process + activation of 4-aminobutyrate catabolism + activation of GABA catabolic process + activation of GABA catabolism + activation of gamma-aminobutyric acid breakdown + activation of gamma-aminobutyric acid catabolism + activation of gamma-aminobutyric acid degradation + positive regulation of 4-aminobutanoate catabolic process + positive regulation of 4-aminobutanoate catabolism + positive regulation of 4-aminobutyrate catabolic process + positive regulation of 4-aminobutyrate catabolism + positive regulation of GABA catabolic process + positive regulation of GABA catabolism + positive regulation of gamma-aminobutyric acid breakdown + positive regulation of gamma-aminobutyric acid catabolism + positive regulation of gamma-aminobutyric acid degradation + up regulation of 4-aminobutanoate catabolic process + up regulation of 4-aminobutanoate catabolism + up regulation of 4-aminobutyrate catabolic process + up regulation of 4-aminobutyrate catabolism + up regulation of GABA catabolic process + up regulation of GABA catabolism + up regulation of gamma-aminobutyric acid breakdown + up regulation of gamma-aminobutyric acid catabolic process + up regulation of gamma-aminobutyric acid catabolism + up regulation of gamma-aminobutyric acid degradation + up-regulation of 4-aminobutanoate catabolic process + up-regulation of 4-aminobutanoate catabolism + up-regulation of 4-aminobutyrate catabolic process + up-regulation of 4-aminobutyrate catabolism + up-regulation of GABA catabolic process + up-regulation of GABA catabolism + up-regulation of gamma-aminobutyric acid breakdown + up-regulation of gamma-aminobutyric acid catabolic process + up-regulation of gamma-aminobutyric acid catabolism + up-regulation of gamma-aminobutyric acid degradation + upregulation of 4-aminobutanoate catabolic process + upregulation of 4-aminobutanoate catabolism + upregulation of 4-aminobutyrate catabolic process + upregulation of 4-aminobutyrate catabolism + upregulation of GABA catabolic process + upregulation of GABA catabolism + upregulation of gamma-aminobutyric acid breakdown + upregulation of gamma-aminobutyric acid catabolic process + upregulation of gamma-aminobutyric acid catabolism + upregulation of gamma-aminobutyric acid degradation + activation of gamma-aminobutyric acid catabolic process + biological_process + GO:1901717 + positive regulation of gamma-aminobutyric acid catabolic process + + + + + Any process that activates or increases the frequency, rate or extent of gamma-aminobutyric acid catabolic process. + GOC:TermGenie + + + + + activation of 4-aminobutanoate catabolic process + GOC:TermGenie + + + + + activation of 4-aminobutanoate catabolism + GOC:TermGenie + + + + + activation of 4-aminobutyrate catabolic process + GOC:TermGenie + + + + + activation of 4-aminobutyrate catabolism + GOC:TermGenie + + + + + activation of GABA catabolic process + GOC:TermGenie + + + + + activation of GABA catabolism + GOC:TermGenie + + + + + activation of gamma-aminobutyric acid breakdown + GOC:TermGenie + + + + + activation of gamma-aminobutyric acid catabolism + GOC:TermGenie + + + + + activation of gamma-aminobutyric acid degradation + GOC:TermGenie + + + + + positive regulation of 4-aminobutanoate catabolic process + GOC:TermGenie + + + + + positive regulation of 4-aminobutanoate catabolism + GOC:TermGenie + + + + + positive regulation of 4-aminobutyrate catabolic process + GOC:TermGenie + + + + + positive regulation of 4-aminobutyrate catabolism + GOC:TermGenie + + + + + positive regulation of GABA catabolic process + GOC:TermGenie + + + + + positive regulation of GABA catabolism + GOC:TermGenie + + + + + positive regulation of gamma-aminobutyric acid breakdown + GOC:TermGenie + + + + + positive regulation of gamma-aminobutyric acid catabolism + GOC:TermGenie + + + + + positive regulation of gamma-aminobutyric acid degradation + GOC:TermGenie + + + + + up regulation of 4-aminobutanoate catabolic process + GOC:TermGenie + + + + + up regulation of 4-aminobutanoate catabolism + GOC:TermGenie + + + + + up regulation of 4-aminobutyrate catabolic process + GOC:TermGenie + + + + + up regulation of 4-aminobutyrate catabolism + GOC:TermGenie + + + + + up regulation of GABA catabolic process + GOC:TermGenie + + + + + up regulation of GABA catabolism + GOC:TermGenie + + + + + up regulation of gamma-aminobutyric acid breakdown + GOC:TermGenie + + + + + up regulation of gamma-aminobutyric acid catabolic process + GOC:TermGenie + + + + + up regulation of gamma-aminobutyric acid catabolism + GOC:TermGenie + + + + + up regulation of gamma-aminobutyric acid degradation + GOC:TermGenie + + + + + up-regulation of 4-aminobutanoate catabolic process + GOC:TermGenie + + + + + up-regulation of 4-aminobutanoate catabolism + GOC:TermGenie + + + + + up-regulation of 4-aminobutyrate catabolic process + GOC:TermGenie + + + + + up-regulation of 4-aminobutyrate catabolism + GOC:TermGenie + + + + + up-regulation of GABA catabolic process + GOC:TermGenie + + + + + up-regulation of GABA catabolism + GOC:TermGenie + + + + + up-regulation of gamma-aminobutyric acid breakdown + GOC:TermGenie + + + + + up-regulation of gamma-aminobutyric acid catabolic process + GOC:TermGenie + + + + + up-regulation of gamma-aminobutyric acid catabolism + GOC:TermGenie + + + + + up-regulation of gamma-aminobutyric acid degradation + GOC:TermGenie + + + + + upregulation of 4-aminobutanoate catabolic process + GOC:TermGenie + + + + + upregulation of 4-aminobutanoate catabolism + GOC:TermGenie + + + + + upregulation of 4-aminobutyrate catabolic process + GOC:TermGenie + + + + + upregulation of 4-aminobutyrate catabolism + GOC:TermGenie + + + + + upregulation of GABA catabolic process + GOC:TermGenie + + + + + upregulation of GABA catabolism + GOC:TermGenie + + + + + upregulation of gamma-aminobutyric acid breakdown + GOC:TermGenie + + + + + upregulation of gamma-aminobutyric acid catabolic process + GOC:TermGenie + + + + + upregulation of gamma-aminobutyric acid catabolism + GOC:TermGenie + + + + + upregulation of gamma-aminobutyric acid degradation + GOC:TermGenie + + + + + activation of gamma-aminobutyric acid catabolic process + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of cell proliferation involved in kidney development. + krc + 2012-12-27T19:30:31Z + biological_process + GO:1901722 + regulation of cell proliferation involved in kidney development + + + + + Any process that modulates the frequency, rate or extent of cell proliferation involved in kidney development. + GOC:TermGenie + PMID:18182616 + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in kidney development. + krc + 2012-12-27T19:30:35Z + down regulation of cell proliferation involved in kidney development + down-regulation of cell proliferation involved in kidney development + downregulation of cell proliferation involved in kidney development + inhibition of cell proliferation involved in kidney development + biological_process + GO:1901723 + negative regulation of cell proliferation involved in kidney development + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in kidney development. + GOC:TermGenie + PMID:18182616 + + + + + down regulation of cell proliferation involved in kidney development + GOC:TermGenie + + + + + down-regulation of cell proliferation involved in kidney development + GOC:TermGenie + + + + + downregulation of cell proliferation involved in kidney development + GOC:TermGenie + + + + + inhibition of cell proliferation involved in kidney development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of cell proliferation involved in kidney development. + krc + 2012-12-27T19:30:40Z + up regulation of cell proliferation involved in kidney development + up-regulation of cell proliferation involved in kidney development + upregulation of cell proliferation involved in kidney development + activation of cell proliferation involved in kidney development + biological_process + GO:1901724 + positive regulation of cell proliferation involved in kidney development + + + + + Any process that activates or increases the frequency, rate or extent of cell proliferation involved in kidney development. + GOC:TermGenie + PMID:18182616 + + + + + up regulation of cell proliferation involved in kidney development + GOC:TermGenie + + + + + up-regulation of cell proliferation involved in kidney development + GOC:TermGenie + + + + + upregulation of cell proliferation involved in kidney development + GOC:TermGenie + + + + + activation of cell proliferation involved in kidney development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways involving zeaxanthin. + yaf + 2013-01-22T11:36:55Z + zeaxanthin metabolism + biological_process + GO:1901825 + zeaxanthin metabolic process + + + + + The chemical reactions and pathways involving zeaxanthin. + GOC:TermGenie + GOC:yaf + MetaCyc:PWY-5944 + UniPathway:UPA00843 + + + + + zeaxanthin metabolism + GOC:TermGenie + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the breakdown of zeaxanthin. + yaf + 2013-01-22T11:37:00Z + zeaxanthin breakdown + zeaxanthin catabolism + zeaxanthin degradation + biological_process + GO:1901826 + zeaxanthin catabolic process + + + + + The chemical reactions and pathways resulting in the breakdown of zeaxanthin. + GOC:TermGenie + GOC:yaf + MetaCyc:PWY-5944 + UniPathway:UPA00843 + + + + + zeaxanthin breakdown + GOC:TermGenie + + + + + zeaxanthin catabolism + GOC:TermGenie + + + + + zeaxanthin degradation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways resulting in the formation of zeaxanthin. + yaf + 2013-01-22T11:37:07Z + zeaxanthin anabolism + zeaxanthin biosynthesis + zeaxanthin formation + zeaxanthin synthesis + biological_process + GO:1901827 + zeaxanthin biosynthetic process + + + + + The chemical reactions and pathways resulting in the formation of zeaxanthin. + GOC:TermGenie + GOC:yaf + MetaCyc:PWY-5944 + UniPathway:UPA00843 + + + + + zeaxanthin anabolism + GOC:TermGenie + + + + + zeaxanthin biosynthesis + GOC:TermGenie + + + + + zeaxanthin formation + GOC:TermGenie + + + + + zeaxanthin synthesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of muscle tissue development. + yaf + 2013-02-01T10:30:47Z + biological_process + GO:1901861 + regulation of muscle tissue development + + + + + Any process that modulates the frequency, rate or extent of muscle tissue development. + GOC:TermGenie + GOC:yaf + PMID:23150719 + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of muscle tissue development. + yaf + 2013-02-01T10:30:52Z + down regulation of muscle tissue development + down-regulation of muscle tissue development + downregulation of muscle tissue development + inhibition of muscle tissue development + biological_process + GO:1901862 + negative regulation of muscle tissue development + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of muscle tissue development. + GOC:TermGenie + GOC:yaf + PMID:23150719 + + + + + down regulation of muscle tissue development + GOC:TermGenie + + + + + down-regulation of muscle tissue development + GOC:TermGenie + + + + + downregulation of muscle tissue development + GOC:TermGenie + + + + + inhibition of muscle tissue development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of muscle tissue development. + yaf + 2013-02-01T10:30:57Z + up regulation of muscle tissue development + up-regulation of muscle tissue development + upregulation of muscle tissue development + activation of muscle tissue development + biological_process + GO:1901863 + positive regulation of muscle tissue development + + + + + Any process that activates or increases the frequency, rate or extent of muscle tissue development. + GOC:TermGenie + GOC:yaf + PMID:23150719 + + + + + up regulation of muscle tissue development + GOC:TermGenie + + + + + up-regulation of muscle tissue development + GOC:TermGenie + + + + + upregulation of muscle tissue development + GOC:TermGenie + + + + + activation of muscle tissue development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of calcium ion binding. + rl + 2013-02-06T12:38:12Z + biological_process + regulation of calcium ion storage activity + GO:1901876 + regulation of calcium ion binding + + + + + Any process that modulates the frequency, rate or extent of calcium ion binding. + GOC:BHF + GOC:TermGenie + GOC:rl + PMID:16432188 + + + + + regulation of calcium ion storage activity + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion binding. + rl + 2013-02-06T12:38:22Z + down regulation of calcium ion binding + down-regulation of calcium ion binding + downregulation of calcium ion binding + inhibition of calcium ion binding + biological_process + down regulation of calcium ion storage activity + down-regulation of calcium ion storage activity + downregulation of calcium ion storage activity + inhibition of calcium ion storage activity + negative regulation of calcium ion storage activity + GO:1901877 + negative regulation of calcium ion binding + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion binding. + GOC:BHF + GOC:TermGenie + GOC:rl + PMID:16432188 + + + + + down regulation of calcium ion binding + GOC:TermGenie + + + + + down-regulation of calcium ion binding + GOC:TermGenie + + + + + downregulation of calcium ion binding + GOC:TermGenie + + + + + inhibition of calcium ion binding + GOC:TermGenie + + + + + down regulation of calcium ion storage activity + GOC:TermGenie + + + + + down-regulation of calcium ion storage activity + GOC:TermGenie + + + + + downregulation of calcium ion storage activity + GOC:TermGenie + + + + + inhibition of calcium ion storage activity + GOC:TermGenie + + + + + negative regulation of calcium ion storage activity + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of calcium ion binding. + rl + 2013-02-06T12:38:26Z + up regulation of calcium ion binding + up-regulation of calcium ion binding + upregulation of calcium ion binding + activation of calcium ion binding + biological_process + activation of calcium ion storage activity + positive regulation of calcium ion storage activity + up regulation of calcium ion storage activity + up-regulation of calcium ion storage activity + upregulation of calcium ion storage activity + GO:1901878 + positive regulation of calcium ion binding + + + + + Any process that activates or increases the frequency, rate or extent of calcium ion binding. + GOC:BHF + GOC:TermGenie + GOC:rl + PMID:16432188 + + + + + up regulation of calcium ion binding + GOC:TermGenie + + + + + up-regulation of calcium ion binding + GOC:TermGenie + + + + + upregulation of calcium ion binding + GOC:TermGenie + + + + + activation of calcium ion binding + GOC:TermGenie + + + + + activation of calcium ion storage activity + GOC:TermGenie + + + + + positive regulation of calcium ion storage activity + GOC:TermGenie + + + + + up regulation of calcium ion storage activity + GOC:TermGenie + + + + + up-regulation of calcium ion storage activity + GOC:TermGenie + + + + + upregulation of calcium ion storage activity + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of cell junction assembly. + tb + 2013-02-06T19:40:32Z + biological_process + GO:1901888 + regulation of cell junction assembly + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate or extent of cell junction assembly. + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cell junction assembly. + tb + 2013-02-06T19:40:41Z + down regulation of cell junction assembly + down-regulation of cell junction assembly + downregulation of cell junction assembly + inhibition of cell junction assembly + biological_process + GO:1901889 + negative regulation of cell junction assembly + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cell junction assembly. + GOC:TermGenie + + + + + down regulation of cell junction assembly + GOC:TermGenie + + + + + down-regulation of cell junction assembly + GOC:TermGenie + + + + + downregulation of cell junction assembly + GOC:TermGenie + + + + + inhibition of cell junction assembly + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of cell junction assembly. + tb + 2013-02-06T19:40:46Z + up regulation of cell junction assembly + up-regulation of cell junction assembly + upregulation of cell junction assembly + activation of cell junction assembly + biological_process + GO:1901890 + positive regulation of cell junction assembly + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that activates or increases the frequency, rate or extent of cell junction assembly. + GOC:TermGenie + + + + + up regulation of cell junction assembly + GOC:TermGenie + + + + + up-regulation of cell junction assembly + GOC:TermGenie + + + + + upregulation of cell junction assembly + GOC:TermGenie + + + + + activation of cell junction assembly + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis. + dph + 2013-02-20T20:30:26Z + biological_process + GO:1901963 + regulation of cell proliferation involved in outflow tract morphogenesis + + + + + Any process that modulates the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis. + GOC:TermGenie + GOC:dph + GOC:mtg_heart + PMID:21419760 + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis. + dph + 2013-02-20T20:30:31Z + up regulation of cell proliferation involved in outflow tract morphogenesis + up-regulation of cell proliferation involved in outflow tract morphogenesis + upregulation of cell proliferation involved in outflow tract morphogenesis + activation of cell proliferation involved in outflow tract morphogenesis + biological_process + GO:1901964 + positive regulation of cell proliferation involved in outflow tract morphogenesis + + + + + Any process that activates or increases the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis. + GOC:TermGenie + GOC:dph + GOC:mtg_heart + PMID:21419760 + + + + + up regulation of cell proliferation involved in outflow tract morphogenesis + GOC:TermGenie + + + + + up-regulation of cell proliferation involved in outflow tract morphogenesis + GOC:TermGenie + + + + + upregulation of cell proliferation involved in outflow tract morphogenesis + GOC:TermGenie + + + + + activation of cell proliferation involved in outflow tract morphogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of cilium assembly. + dph + 2013-03-26T18:10:51Z + regulation of ciliogenesis + biological_process + regulation of cilium biogenesis + GO:1902017 + regulation of cilium assembly + + + + + Any process that modulates the frequency, rate or extent of cilium assembly. + GOC:TermGenie + GOC:cilia + GOC:dph + PMID:17719545 + + + + + regulation of ciliogenesis + GOC:TermGenie + + + + + regulation of cilium biogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cilium assembly. + dph + 2013-03-26T18:10:56Z + down regulation of ciliogenesis + down regulation of cilium assembly + down-regulation of ciliogenesis + down-regulation of cilium assembly + downregulation of ciliogenesis + downregulation of cilium assembly + inhibition of ciliogenesis + negative regulation of ciliogenesis + inhibition of cilium assembly + biological_process + down regulation of cilium biogenesis + down-regulation of cilium biogenesis + downregulation of cilium biogenesis + inhibition of cilium biogenesis + negative regulation of cilium biogenesis + GO:1902018 + negative regulation of cilium assembly + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cilium assembly. + GOC:TermGenie + GOC:cilia + GOC:dph + PMID:17719545 + + + + + down regulation of ciliogenesis + GOC:TermGenie + + + + + down regulation of cilium assembly + GOC:TermGenie + + + + + down-regulation of ciliogenesis + GOC:TermGenie + + + + + down-regulation of cilium assembly + GOC:TermGenie + + + + + downregulation of ciliogenesis + GOC:TermGenie + + + + + downregulation of cilium assembly + GOC:TermGenie + + + + + inhibition of ciliogenesis + GOC:TermGenie + + + + + negative regulation of ciliogenesis + GOC:TermGenie + + + + + inhibition of cilium assembly + GOC:TermGenie + + + + + down regulation of cilium biogenesis + GOC:TermGenie + + + + + down-regulation of cilium biogenesis + GOC:TermGenie + + + + + downregulation of cilium biogenesis + GOC:TermGenie + + + + + inhibition of cilium biogenesis + GOC:TermGenie + + + + + negative regulation of cilium biogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of cilium-dependent cell motility. + jl + 2013-03-27T14:42:38Z + regulation of cilium cell motility + biological_process + regulation of ciliary cell motility + GO:1902019 + regulation of cilium-dependent cell motility + + + + + Any process that modulates the frequency, rate or extent of cilium-dependent cell motility. + GOC:TermGenie + GOC:cilia + GOC:jl + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cilium-dependent cell motility. + jl + 2013-03-27T14:42:42Z + down regulation of ciliary cell motility + down-regulation of ciliary cell motility + downregulation of ciliary cell motility + negative regulation of cilium cell motility + inhibition of ciliary cell motility + biological_process + negative regulation of ciliary cell motility + GO:1902020 + negative regulation of cilium-dependent cell motility + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cilium-dependent cell motility. + GOC:TermGenie + GOC:cilia + GOC:jl + + + + + down regulation of ciliary cell motility + GOC:TermGenie + + + + + down-regulation of ciliary cell motility + GOC:TermGenie + + + + + downregulation of ciliary cell motility + GOC:TermGenie + + + + + inhibition of ciliary cell motility + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of flagellated sperm motility. + bf + 2013-04-29T09:15:25Z + activation of sperm movement + positive regulation of sperm motility + positive regulation of sperm movement + up regulation of sperm motility + up regulation of sperm movement + up-regulation of sperm motility + up-regulation of sperm movement + upregulation of sperm motility + upregulation of sperm movement + activation of sperm motility + biological_process + GO:1902093 + positive regulation of flagellated sperm motility + + + + + Any process that activates or increases the frequency, rate or extent of flagellated sperm motility. + GOC:TermGenie + GOC:cilia + GOC:jh2 + GOC:krc + PMID:7513657 + + + + + activation of sperm movement + GOC:TermGenie + + + + + positive regulation of sperm movement + GOC:TermGenie + + + + + up regulation of sperm motility + GOC:TermGenie + + + + + up regulation of sperm movement + GOC:TermGenie + + + + + up-regulation of sperm motility + GOC:TermGenie + + + + + up-regulation of sperm movement + GOC:TermGenie + + + + + upregulation of sperm motility + GOC:TermGenie + + + + + upregulation of sperm movement + GOC:TermGenie + + + + + activation of sperm motility + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of leukocyte differentiation. + pr + 2013-05-02T17:32:42Z + regulation of immune cell differentiation + regulation of leucocyte differentiation + biological_process + GO:1902105 + regulation of leukocyte differentiation + + + + + Any process that modulates the frequency, rate or extent of leukocyte differentiation. + GOC:TermGenie + GOC:add + + + + + regulation of immune cell differentiation + GOC:TermGenie + + + + + regulation of leucocyte differentiation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte differentiation. + pr + 2013-05-02T17:32:47Z + down regulation of immune cell differentiation + down regulation of leucocyte differentiation + down regulation of leukocyte differentiation + down-regulation of immune cell differentiation + down-regulation of leucocyte differentiation + down-regulation of leukocyte differentiation + downregulation of immune cell differentiation + downregulation of leucocyte differentiation + downregulation of leukocyte differentiation + negative regulation of immune cell differentiation + negative regulation of leucocyte differentiation + inhibition of immune cell differentiation + inhibition of leucocyte differentiation + inhibition of leukocyte differentiation + biological_process + GO:1902106 + negative regulation of leukocyte differentiation + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte differentiation. + GOC:TermGenie + GOC:add + + + + + down regulation of immune cell differentiation + GOC:TermGenie + + + + + down regulation of leucocyte differentiation + GOC:TermGenie + + + + + down regulation of leukocyte differentiation + GOC:TermGenie + + + + + down-regulation of immune cell differentiation + GOC:TermGenie + + + + + down-regulation of leucocyte differentiation + GOC:TermGenie + + + + + down-regulation of leukocyte differentiation + GOC:TermGenie + + + + + downregulation of immune cell differentiation + GOC:TermGenie + + + + + downregulation of leucocyte differentiation + GOC:TermGenie + + + + + downregulation of leukocyte differentiation + GOC:TermGenie + + + + + negative regulation of immune cell differentiation + GOC:TermGenie + + + + + negative regulation of leucocyte differentiation + GOC:TermGenie + + + + + inhibition of immune cell differentiation + GOC:TermGenie + + + + + inhibition of leucocyte differentiation + GOC:TermGenie + + + + + inhibition of leukocyte differentiation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of leukocyte differentiation. + pr + 2013-05-02T17:32:52Z + positive regulation of immune cell differentiation + positive regulation of leucocyte differentiation + up regulation of immune cell differentiation + up regulation of leucocyte differentiation + up regulation of leukocyte differentiation + up-regulation of immune cell differentiation + up-regulation of leucocyte differentiation + up-regulation of leukocyte differentiation + upregulation of immune cell differentiation + upregulation of leucocyte differentiation + upregulation of leukocyte differentiation + activation of immune cell differentiation + activation of leucocyte differentiation + activation of leukocyte differentiation + biological_process + GO:1902107 + positive regulation of leukocyte differentiation + + + + + Any process that activates or increases the frequency, rate or extent of leukocyte differentiation. + GOC:TermGenie + GOC:add + + + + + positive regulation of immune cell differentiation + GOC:TermGenie + + + + + positive regulation of leucocyte differentiation + GOC:TermGenie + + + + + up regulation of immune cell differentiation + GOC:TermGenie + + + + + up regulation of leucocyte differentiation + GOC:TermGenie + + + + + up regulation of leukocyte differentiation + GOC:TermGenie + + + + + up-regulation of immune cell differentiation + GOC:TermGenie + + + + + up-regulation of leucocyte differentiation + GOC:TermGenie + + + + + up-regulation of leukocyte differentiation + GOC:TermGenie + + + + + upregulation of immune cell differentiation + GOC:TermGenie + + + + + upregulation of leucocyte differentiation + GOC:TermGenie + + + + + upregulation of leukocyte differentiation + GOC:TermGenie + + + + + activation of immune cell differentiation + GOC:TermGenie + + + + + activation of leucocyte differentiation + GOC:TermGenie + + + + + activation of leukocyte differentiation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of organelle assembly. + pr + 2013-05-14T09:43:21Z + biological_process + GO:1902115 + regulation of organelle assembly + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate or extent of organelle assembly. + GOC:TermGenie + GOC:pr + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of organelle assembly. + pr + 2013-05-14T09:43:31Z + down regulation of organelle assembly + down-regulation of organelle assembly + downregulation of organelle assembly + inhibition of organelle assembly + biological_process + GO:1902116 + negative regulation of organelle assembly + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of organelle assembly. + GOC:TermGenie + GOC:pr + + + + + down regulation of organelle assembly + GOC:TermGenie + + + + + down-regulation of organelle assembly + GOC:TermGenie + + + + + downregulation of organelle assembly + GOC:TermGenie + + + + + inhibition of organelle assembly + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of organelle assembly. + pr + 2013-05-14T09:43:36Z + up regulation of organelle assembly + up-regulation of organelle assembly + upregulation of organelle assembly + activation of organelle assembly + biological_process + GO:1902117 + positive regulation of organelle assembly + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that activates or increases the frequency, rate or extent of organelle assembly. + GOC:TermGenie + GOC:pr + + + + + up regulation of organelle assembly + GOC:TermGenie + + + + + up-regulation of organelle assembly + GOC:TermGenie + + + + + upregulation of organelle assembly + GOC:TermGenie + + + + + activation of organelle assembly + GOC:TermGenie + + + + + + + + + + + + + + + + + + + A process in which a protein is transported to, or maintained in, a location within a bicellular tight junction. + tb + 2013-09-11T21:43:13Z + protein localisation in tight junction + protein localisation to tight junction + protein localization in tight junction + biological_process + GO:1902396 + protein localization to bicellular tight junction + + + + + A process in which a protein is transported to, or maintained in, a location within a bicellular tight junction. + GOC:TermGenie + PMID:18332111 + + + + + protein localisation in tight junction + GOC:TermGenie + + + + + protein localisation to tight junction + GOC:TermGenie + + + + + protein localization in tight junction + GOC:TermGenie + + + + + + + + + + + + + + + + + + + A process in which a protein is transported to, or maintained in, a location within a cell junction. + tb + 2013-09-13T16:55:57Z + protein localisation in cell junction + protein localisation to cell junction + protein localization in cell junction + biological_process + GO:1902414 + protein localization to cell junction + + + + + A process in which a protein is transported to, or maintained in, a location within a cell junction. + GOC:TermGenie + PMID:18332111 + + + + + protein localisation in cell junction + GOC:TermGenie + + + + + protein localisation to cell junction + GOC:TermGenie + + + + + protein localization in cell junction + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + A process in which a protein is transported to, or maintained in, a location within a cell leading edge. + jl + 2013-10-22T12:36:07Z + protein localisation in cell leading edge + protein localisation to cell leading edge + protein localization in cell leading edge + biological_process + GO:1902463 + protein localization to cell leading edge + + + + + A process in which a protein is transported to, or maintained in, a location within a cell leading edge. + GOC:TermGenie + GOC:lb + PMID:21543326 + + + + + protein localisation in cell leading edge + GOC:TermGenie + + + + + protein localisation to cell leading edge + GOC:TermGenie + + + + + protein localization in cell leading edge + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of sperm capacitation. + hjd + 2013-11-12T21:17:03Z + biological_process + regulation of sperm activation + GO:1902490 + regulation of sperm capacitation + + + + + Any process that modulates the frequency, rate or extent of sperm capacitation. + GOC:TermGenie + GOC:hjd + PMID:22539676 + + + + + regulation of sperm activation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of sperm capacitation. + hjd + 2013-11-12T21:17:12Z + down regulation of sperm capacitation + down-regulation of sperm capacitation + downregulation of sperm capacitation + inhibition of sperm capacitation + biological_process + down regulation of sperm activation + down-regulation of sperm activation + downregulation of sperm activation + inhibition of sperm activation + negative regulation of sperm activation + GO:1902491 + negative regulation of sperm capacitation + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of sperm capacitation. + GOC:TermGenie + GOC:hjd + PMID:22539676 + + + + + down regulation of sperm capacitation + GOC:TermGenie + + + + + down-regulation of sperm capacitation + GOC:TermGenie + + + + + downregulation of sperm capacitation + GOC:TermGenie + + + + + inhibition of sperm capacitation + GOC:TermGenie + + + + + down regulation of sperm activation + GOC:TermGenie + + + + + down-regulation of sperm activation + GOC:TermGenie + + + + + downregulation of sperm activation + GOC:TermGenie + + + + + inhibition of sperm activation + GOC:TermGenie + + + + + negative regulation of sperm activation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of sperm capacitation. + hjd + 2013-11-12T21:17:21Z + up regulation of sperm capacitation + up-regulation of sperm capacitation + upregulation of sperm capacitation + activation of sperm capacitation + biological_process + activation of sperm activation + positive regulation of sperm activation + up regulation of sperm activation + up-regulation of sperm activation + upregulation of sperm activation + GO:1902492 + positive regulation of sperm capacitation + + + + + Any process that activates or increases the frequency, rate or extent of sperm capacitation. + GOC:TermGenie + GOC:hjd + PMID:22539676 + + + + + up regulation of sperm capacitation + GOC:TermGenie + + + + + up-regulation of sperm capacitation + GOC:TermGenie + + + + + upregulation of sperm capacitation + GOC:TermGenie + + + + + activation of sperm capacitation + GOC:TermGenie + + + + + activation of sperm activation + GOC:TermGenie + + + + + positive regulation of sperm activation + GOC:TermGenie + + + + + up regulation of sperm activation + GOC:TermGenie + + + + + up-regulation of sperm activation + GOC:TermGenie + + + + + upregulation of sperm activation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + A protein complex which is capable of catalytic activity. + bhm + 2013-11-13T16:18:47Z + enzyme complex + cellular_component + GO:1902494 + + catalytic complex + + + + + A protein complex which is capable of catalytic activity. + GOC:TermGenie + GOC:bhm + PMID:8077207 + + + + + enzyme complex + GOC:bhm + GOC:jl + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of organelle transport along microtubule. + dph + 2013-11-15T20:15:17Z + regulation of microtubule-based organelle localization + biological_process + GO:1902513 + regulation of organelle transport along microtubule + + + + + Any process that modulates the frequency, rate or extent of organelle transport along microtubule. + GOC:TermGenie + GOC:dph + PMID:21147087 + + + + + regulation of microtubule-based organelle localization + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of intracellular signal transduction. + bf + 2013-12-02T11:32:52Z + GO:0010627 + regulation of intracellular signaling cascade + regulation of intracellular signaling chain + regulation of intracellular protein kinase cascade + regulation of intracellular signal transduction pathway + regulation of signal transmission via intracellular cascade + biological_process + regulation of intracellular signaling pathway + regulation of signal transduction via intracellular signaling cascade + GO:1902531 + regulation of intracellular signal transduction + + + + + Any process that modulates the frequency, rate or extent of intracellular signal transduction. + GOC:TermGenie + GOC:dph + GOC:signaling + GOC:tb + + + + + regulation of intracellular signaling cascade + GOC:TermGenie + + + + + regulation of intracellular signaling chain + GOC:TermGenie + + + + + regulation of intracellular signal transduction pathway + GOC:TermGenie + + + + + regulation of signal transmission via intracellular cascade + GOC:TermGenie + + + + + regulation of intracellular signaling pathway + GOC:TermGenie + + + + + regulation of signal transduction via intracellular signaling cascade + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction. + bf + 2013-12-02T11:33:01Z + GO:0010741 + down regulation of intracellular signal transduction + down regulation of intracellular signaling chain + down-regulation of intracellular signal transduction + down-regulation of intracellular signaling chain + downregulation of intracellular signal transduction + downregulation of intracellular signaling chain + negative regulation of intracellular protein kinase cascade + negative regulation of intracellular signaling cascade + negative regulation of intracellular signaling chain + down regulation of intracellular signal transduction pathway + down regulation of intracellular signaling cascade + down regulation of signal transmission via intracellular cascade + down-regulation of intracellular signal transduction pathway + downregulation of intracellular signal transduction pathway + downregulation of intracellular signaling cascade + downregulation of signal transmission via intracellular cascade + inhibition of intracellular signal transduction + inhibition of intracellular signal transduction pathway + inhibition of intracellular signaling cascade + inhibition of intracellular signaling chain + inhibition of signal transmission via intracellular cascade + negative regulation of intracellular signal transduction pathway + negative regulation of signal transmission via intracellular cascade + biological_process + down regulation of intracellular signaling pathway + down regulation of signal transduction via intracellular signaling cascade + down-regulation of intracellular signaling cascade + down-regulation of intracellular signaling pathway + down-regulation of signal transduction via intracellular signaling cascade + down-regulation of signal transmission via intracellular cascade + downregulation of intracellular signaling pathway + downregulation of signal transduction via intracellular signaling cascade + inhibition of intracellular signaling pathway + inhibition of signal transduction via intracellular signaling cascade + negative regulation of intracellular signaling pathway + negative regulation of signal transduction via intracellular signaling cascade + GO:1902532 + negative regulation of intracellular signal transduction + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction. + GOC:TermGenie + GOC:dph + GOC:signaling + GOC:tb + + + + + down regulation of intracellular signal transduction + GOC:TermGenie + + + + + down regulation of intracellular signaling chain + GOC:TermGenie + + + + + down-regulation of intracellular signal transduction + GOC:TermGenie + + + + + down-regulation of intracellular signaling chain + GOC:TermGenie + + + + + downregulation of intracellular signal transduction + GOC:TermGenie + + + + + downregulation of intracellular signaling chain + GOC:TermGenie + + + + + negative regulation of intracellular signaling cascade + GOC:TermGenie + + + + + negative regulation of intracellular signaling chain + GOC:TermGenie + + + + + down regulation of intracellular signal transduction pathway + GOC:TermGenie + + + + + down regulation of intracellular signaling cascade + GOC:TermGenie + + + + + down regulation of signal transmission via intracellular cascade + GOC:TermGenie + + + + + down-regulation of intracellular signal transduction pathway + GOC:TermGenie + + + + + downregulation of intracellular signal transduction pathway + GOC:TermGenie + + + + + downregulation of intracellular signaling cascade + GOC:TermGenie + + + + + downregulation of signal transmission via intracellular cascade + GOC:TermGenie + + + + + inhibition of intracellular signal transduction + GOC:TermGenie + + + + + inhibition of intracellular signal transduction pathway + GOC:TermGenie + + + + + inhibition of intracellular signaling cascade + GOC:TermGenie + + + + + inhibition of intracellular signaling chain + GOC:TermGenie + + + + + inhibition of signal transmission via intracellular cascade + GOC:TermGenie + + + + + negative regulation of intracellular signal transduction pathway + GOC:TermGenie + + + + + negative regulation of signal transmission via intracellular cascade + GOC:TermGenie + + + + + down regulation of intracellular signaling pathway + GOC:TermGenie + + + + + down regulation of signal transduction via intracellular signaling cascade + GOC:TermGenie + + + + + down-regulation of intracellular signaling cascade + GOC:TermGenie + + + + + down-regulation of intracellular signaling pathway + GOC:TermGenie + + + + + down-regulation of signal transduction via intracellular signaling cascade + GOC:TermGenie + + + + + down-regulation of signal transmission via intracellular cascade + GOC:TermGenie + + + + + downregulation of intracellular signaling pathway + GOC:TermGenie + + + + + downregulation of signal transduction via intracellular signaling cascade + GOC:TermGenie + + + + + inhibition of intracellular signaling pathway + GOC:TermGenie + + + + + inhibition of signal transduction via intracellular signaling cascade + GOC:TermGenie + + + + + negative regulation of intracellular signaling pathway + GOC:TermGenie + + + + + negative regulation of signal transduction via intracellular signaling cascade + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of intracellular signal transduction. + bf + 2013-12-02T11:33:10Z + GO:0010740 + positive regulation of intracellular signaling chain + up regulation of intracellular signal transduction + up regulation of intracellular signaling chain + up-regulation of intracellular signal transduction + up-regulation of intracellular signaling chain + upregulation of intracellular signal transduction + upregulation of intracellular signaling chain + activation of intracellular signal transduction + activation of intracellular signal transduction pathway + activation of intracellular signaling cascade + activation of intracellular signaling chain + activation of signal transmission via intracellular cascade + positive regulation of intracellular protein kinase cascade + positive regulation of intracellular signal transduction pathway + positive regulation of signal transmission via intracellular cascade + up regulation of intracellular signal transduction pathway + up regulation of signal transmission via intracellular cascade + up-regulation of intracellular signal transduction pathway + up-regulation of signal transmission via intracellular cascade + upregulation of intracellular signal transduction pathway + upregulation of signal transmission via intracellular cascade + biological_process + activation of intracellular signaling pathway + activation of signal transduction via intracellular signaling cascade + positive regulation of intracellular signaling cascade + positive regulation of intracellular signaling pathway + positive regulation of signal transduction via intracellular signaling cascade + up regulation of intracellular signaling cascade + up regulation of intracellular signaling pathway + up regulation of signal transduction via intracellular signaling cascade + up-regulation of intracellular signaling cascade + up-regulation of intracellular signaling pathway + up-regulation of signal transduction via intracellular signaling cascade + upregulation of intracellular signaling cascade + upregulation of intracellular signaling pathway + upregulation of signal transduction via intracellular signaling cascade + GO:1902533 + positive regulation of intracellular signal transduction + + + + + Any process that activates or increases the frequency, rate or extent of intracellular signal transduction. + GOC:BHF + GOC:TermGenie + GOC:dph + GOC:signaling + GOC:tb + + + + + positive regulation of intracellular signaling chain + GOC:TermGenie + + + + + up regulation of intracellular signal transduction + GOC:TermGenie + + + + + up regulation of intracellular signaling chain + GOC:TermGenie + + + + + up-regulation of intracellular signal transduction + GOC:TermGenie + + + + + up-regulation of intracellular signaling chain + GOC:TermGenie + + + + + upregulation of intracellular signal transduction + GOC:TermGenie + + + + + upregulation of intracellular signaling chain + GOC:TermGenie + + + + + activation of intracellular signal transduction + GOC:TermGenie + + + + + activation of intracellular signal transduction pathway + GOC:TermGenie + + + + + activation of intracellular signaling cascade + GOC:TermGenie + + + + + activation of intracellular signaling chain + GOC:TermGenie + + + + + activation of signal transmission via intracellular cascade + GOC:TermGenie + + + + + positive regulation of intracellular signal transduction pathway + GOC:TermGenie + + + + + positive regulation of signal transmission via intracellular cascade + GOC:TermGenie + + + + + up regulation of intracellular signal transduction pathway + GOC:TermGenie + + + + + up regulation of signal transmission via intracellular cascade + GOC:TermGenie + + + + + up-regulation of intracellular signal transduction pathway + GOC:TermGenie + + + + + up-regulation of signal transmission via intracellular cascade + GOC:TermGenie + + + + + upregulation of intracellular signal transduction pathway + GOC:TermGenie + + + + + upregulation of signal transmission via intracellular cascade + GOC:TermGenie + + + + + activation of intracellular signaling pathway + GOC:TermGenie + + + + + activation of signal transduction via intracellular signaling cascade + GOC:TermGenie + + + + + positive regulation of intracellular signaling cascade + GOC:TermGenie + + + + + positive regulation of intracellular signaling pathway + GOC:TermGenie + + + + + positive regulation of signal transduction via intracellular signaling cascade + GOC:TermGenie + + + + + up regulation of intracellular signaling cascade + GOC:TermGenie + + + + + up regulation of intracellular signaling pathway + GOC:TermGenie + + + + + up regulation of signal transduction via intracellular signaling cascade + GOC:TermGenie + + + + + up-regulation of intracellular signaling cascade + GOC:TermGenie + + + + + up-regulation of intracellular signaling pathway + GOC:TermGenie + + + + + up-regulation of signal transduction via intracellular signaling cascade + GOC:TermGenie + + + + + upregulation of intracellular signaling cascade + GOC:TermGenie + + + + + upregulation of intracellular signaling pathway + GOC:TermGenie + + + + + upregulation of signal transduction via intracellular signaling cascade + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of response to water deprivation. + tb + 2013-12-19T00:31:58Z + positive regulation of response to dehydration + positive regulation of response to drought + positive regulation of response to thirst + up regulation of response to dehydration + up regulation of response to drought + up regulation of response to thirst + up regulation of response to water deprivation + up-regulation of response to dehydration + up-regulation of response to drought + up-regulation of response to thirst + up-regulation of response to water deprivation + upregulation of response to dehydration + upregulation of response to drought + upregulation of response to thirst + upregulation of response to water deprivation + activation of response to dehydration + activation of response to drought + activation of response to thirst + activation of response to water deprivation + biological_process + activation of drought tolerance + positive regulation of drought tolerance + up regulation of drought tolerance + up-regulation of drought tolerance + upregulation of drought tolerance + GO:1902584 + positive regulation of response to water deprivation + + + + + Any process that activates or increases the frequency, rate or extent of response to water deprivation. + GOC:TermGenie + GO_REF:0000058 + PMID:24198318 + + + + + positive regulation of response to dehydration + GOC:TermGenie + + + + + positive regulation of response to drought + GOC:TermGenie + + + + + positive regulation of response to thirst + GOC:TermGenie + + + + + up regulation of response to dehydration + GOC:TermGenie + + + + + up regulation of response to drought + GOC:TermGenie + + + + + up regulation of response to thirst + GOC:TermGenie + + + + + up regulation of response to water deprivation + GOC:TermGenie + + + + + up-regulation of response to dehydration + GOC:TermGenie + + + + + up-regulation of response to drought + GOC:TermGenie + + + + + up-regulation of response to thirst + GOC:TermGenie + + + + + up-regulation of response to water deprivation + GOC:TermGenie + + + + + upregulation of response to dehydration + GOC:TermGenie + + + + + upregulation of response to drought + GOC:TermGenie + + + + + upregulation of response to thirst + GOC:TermGenie + + + + + upregulation of response to water deprivation + GOC:TermGenie + + + + + activation of response to dehydration + GOC:TermGenie + + + + + activation of response to drought + GOC:TermGenie + + + + + activation of response to thirst + GOC:TermGenie + + + + + activation of response to water deprivation + GOC:TermGenie + + + + + activation of drought tolerance + GOC:TermGenie + + + + + positive regulation of drought tolerance + GOC:TermGenie + + + + + up regulation of drought tolerance + GOC:TermGenie + + + + + up-regulation of drought tolerance + GOC:TermGenie + + + + + upregulation of drought tolerance + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any neural crest cell differentiation that is involved in thymus development. + pr + 2014-01-21T10:03:20Z + biological_process + GO:1902637 + neural crest cell differentiation involved in thymus development + + + + + Any neural crest cell differentiation that is involved in thymus development. + GOC:TermGenie + GOC:nhn + GO_REF:0000060 + PMID:15741317 + PMID:18292542 + + + + + + + + + + + + + + + + + + + Any neural crest cell differentiation that is involved in parathyroid gland development. + pr + 2014-01-21T10:03:29Z + biological_process + GO:1902638 + neural crest cell differentiation involved in parathyroid gland development + + + + + Any neural crest cell differentiation that is involved in parathyroid gland development. + GOC:TermGenie + GOC:nhn + GO_REF:0000060 + PMID:15741317 + + + + + + + + + + + + + + + + + + + Binding to carbon dioxide. + bhm + 2014-02-04T10:38:41Z + CO2 binding + molecular_function + GO:1902670 + carbon dioxide binding + + + + + Binding to carbon dioxide. + GOC:TermGenie + GOC:bhm + GO_REF:0000067 + PMID:15491402 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of neuroblast proliferation. + rl + 2014-02-18T10:03:31Z + biological_process + GO:1902692 + regulation of neuroblast proliferation + + + + + Any process that modulates the frequency, rate or extent of neuroblast proliferation. + GOC:PARL + GOC:TermGenie + GOC:rl + GO_REF:0000058 + PMID:21168496 + + + + + + + + + + + + + + + + + + + A protein complex which is capable of GABA receptor activity. Upon binding of gamma-aminobutyric acid (GABA) it transmits the signal from one side of the membrane to the other to initiate a change in cell activity. Major inhibitory receptor in vertebrate brain. Also found in other vertebrate tissues, invertebrates and possibly in plants. Effective benzodiazepine receptor. + bhm + 2014-02-20T16:07:48Z + gamma-aminobutyric acid receptor complex + cellular_component + GO:1902710 + GABA receptor complex + + + + + A protein complex which is capable of GABA receptor activity. Upon binding of gamma-aminobutyric acid (GABA) it transmits the signal from one side of the membrane to the other to initiate a change in cell activity. Major inhibitory receptor in vertebrate brain. Also found in other vertebrate tissues, invertebrates and possibly in plants. Effective benzodiazepine receptor. + GOC:TermGenie + GOC:bhm + GO_REF:0000088 + PMID:18790874 + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans. + mr + 2014-02-24T16:10:43Z + down regulation of proteoglycan anabolism + down regulation of proteoglycan biosynthesis + down regulation of proteoglycan biosynthetic process + down regulation of proteoglycan formation + down regulation of proteoglycan synthesis + down-regulation of proteoglycan anabolism + down-regulation of proteoglycan biosynthesis + down-regulation of proteoglycan biosynthetic process + down-regulation of proteoglycan formation + down-regulation of proteoglycan synthesis + downregulation of proteoglycan anabolism + downregulation of proteoglycan biosynthesis + downregulation of proteoglycan biosynthetic process + downregulation of proteoglycan formation + downregulation of proteoglycan synthesis + negative regulation of proteoglycan anabolism + negative regulation of proteoglycan biosynthesis + negative regulation of proteoglycan formation + negative regulation of proteoglycan synthesis + inhibition of proteoglycan anabolism + inhibition of proteoglycan biosynthesis + inhibition of proteoglycan biosynthetic process + inhibition of proteoglycan formation + inhibition of proteoglycan synthesis + biological_process + GO:1902729 + negative regulation of proteoglycan biosynthetic process + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans. + GOC:TermGenie + GO_REF:0000058 + PMID:23212449 + + + + + down regulation of proteoglycan anabolism + GOC:TermGenie + + + + + down regulation of proteoglycan biosynthesis + GOC:TermGenie + + + + + down regulation of proteoglycan biosynthetic process + GOC:TermGenie + + + + + down regulation of proteoglycan formation + GOC:TermGenie + + + + + down regulation of proteoglycan synthesis + GOC:TermGenie + + + + + down-regulation of proteoglycan anabolism + GOC:TermGenie + + + + + down-regulation of proteoglycan biosynthesis + GOC:TermGenie + + + + + down-regulation of proteoglycan biosynthetic process + GOC:TermGenie + + + + + down-regulation of proteoglycan formation + GOC:TermGenie + + + + + down-regulation of proteoglycan synthesis + GOC:TermGenie + + + + + downregulation of proteoglycan anabolism + GOC:TermGenie + + + + + downregulation of proteoglycan biosynthesis + GOC:TermGenie + + + + + downregulation of proteoglycan biosynthetic process + GOC:TermGenie + + + + + downregulation of proteoglycan formation + GOC:TermGenie + + + + + downregulation of proteoglycan synthesis + GOC:TermGenie + + + + + negative regulation of proteoglycan anabolism + GOC:TermGenie + + + + + negative regulation of proteoglycan biosynthesis + GOC:TermGenie + + + + + negative regulation of proteoglycan formation + GOC:TermGenie + + + + + negative regulation of proteoglycan synthesis + GOC:TermGenie + + + + + inhibition of proteoglycan anabolism + GOC:TermGenie + + + + + inhibition of proteoglycan biosynthesis + GOC:TermGenie + + + + + inhibition of proteoglycan biosynthetic process + GOC:TermGenie + + + + + inhibition of proteoglycan formation + GOC:TermGenie + + + + + inhibition of proteoglycan synthesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans. + mr + 2014-02-24T16:10:52Z + positive regulation of proteoglycan anabolism + positive regulation of proteoglycan biosynthesis + positive regulation of proteoglycan formation + positive regulation of proteoglycan synthesis + up regulation of proteoglycan anabolism + up regulation of proteoglycan biosynthesis + up regulation of proteoglycan biosynthetic process + up regulation of proteoglycan formation + up regulation of proteoglycan synthesis + up-regulation of proteoglycan anabolism + up-regulation of proteoglycan biosynthesis + up-regulation of proteoglycan biosynthetic process + up-regulation of proteoglycan formation + up-regulation of proteoglycan synthesis + upregulation of proteoglycan anabolism + upregulation of proteoglycan biosynthesis + upregulation of proteoglycan biosynthetic process + upregulation of proteoglycan formation + upregulation of proteoglycan synthesis + activation of proteoglycan anabolism + activation of proteoglycan biosynthesis + activation of proteoglycan biosynthetic process + activation of proteoglycan formation + activation of proteoglycan synthesis + biological_process + GO:1902730 + positive regulation of proteoglycan biosynthetic process + + + + + Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans. + GOC:TermGenie + GO_REF:0000058 + PMID:23212449 + + + + + positive regulation of proteoglycan anabolism + GOC:TermGenie + + + + + positive regulation of proteoglycan biosynthesis + GOC:TermGenie + + + + + positive regulation of proteoglycan formation + GOC:TermGenie + + + + + positive regulation of proteoglycan synthesis + GOC:TermGenie + + + + + up regulation of proteoglycan anabolism + GOC:TermGenie + + + + + up regulation of proteoglycan biosynthesis + GOC:TermGenie + + + + + up regulation of proteoglycan biosynthetic process + GOC:TermGenie + + + + + up regulation of proteoglycan formation + GOC:TermGenie + + + + + up regulation of proteoglycan synthesis + GOC:TermGenie + + + + + up-regulation of proteoglycan anabolism + GOC:TermGenie + + + + + up-regulation of proteoglycan biosynthesis + GOC:TermGenie + + + + + up-regulation of proteoglycan biosynthetic process + GOC:TermGenie + + + + + up-regulation of proteoglycan formation + GOC:TermGenie + + + + + up-regulation of proteoglycan synthesis + GOC:TermGenie + + + + + upregulation of proteoglycan anabolism + GOC:TermGenie + + + + + upregulation of proteoglycan biosynthesis + GOC:TermGenie + + + + + upregulation of proteoglycan biosynthetic process + GOC:TermGenie + + + + + upregulation of proteoglycan formation + GOC:TermGenie + + + + + upregulation of proteoglycan synthesis + GOC:TermGenie + + + + + activation of proteoglycan anabolism + GOC:TermGenie + + + + + activation of proteoglycan biosynthesis + GOC:TermGenie + + + + + activation of proteoglycan biosynthetic process + GOC:TermGenie + + + + + activation of proteoglycan formation + GOC:TermGenie + + + + + activation of proteoglycan synthesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the rate, frequency, or extent of the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the growth of a bone. A chondrocyte is a polymorphic cell that forms cartilage. + mr + 2014-02-24T16:11:28Z + biological_process + GO:1902733 + regulation of growth plate cartilage chondrocyte differentiation + + + + + Any process that modulates the rate, frequency, or extent of the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the growth of a bone. A chondrocyte is a polymorphic cell that forms cartilage. + GOC:TermGenie + GO_REF:0000058 + PMID:23212449 + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the rate, frequency, or extent of the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage. + mr + 2014-02-26T15:36:15Z + biological_process + GO:1902738 + regulation of chondrocyte differentiation involved in endochondral bone morphogenesis + + + + + Any process that modulates the rate, frequency, or extent of the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage. + GOC:TermGenie + GO_REF:0000058 + PMID:8662546 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of lens fiber cell differentiation. + mr + 2014-03-03T23:18:50Z + regulation of lens fibre cell differentiation + biological_process + GO:1902746 + regulation of lens fiber cell differentiation + + + + + Any process that modulates the frequency, rate or extent of lens fiber cell differentiation. + GOC:TermGenie + GOC:mr + GO_REF:0000058 + PMID:17592637 + + + + + regulation of lens fibre cell differentiation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of lens fiber cell differentiation. + mr + 2014-03-03T23:19:32Z + down regulation of lens fiber cell differentiation + down regulation of lens fibre cell differentiation + down-regulation of lens fiber cell differentiation + down-regulation of lens fibre cell differentiation + downregulation of lens fiber cell differentiation + downregulation of lens fibre cell differentiation + negative regulation of lens fibre cell differentiation + inhibition of lens fiber cell differentiation + inhibition of lens fibre cell differentiation + biological_process + GO:1902747 + negative regulation of lens fiber cell differentiation + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of lens fiber cell differentiation. + GOC:TermGenie + GOC:mr + GO_REF:0000058 + PMID:17592637 + + + + + down regulation of lens fiber cell differentiation + GOC:TermGenie + + + + + down regulation of lens fibre cell differentiation + GOC:TermGenie + + + + + down-regulation of lens fiber cell differentiation + GOC:TermGenie + + + + + down-regulation of lens fibre cell differentiation + GOC:TermGenie + + + + + downregulation of lens fiber cell differentiation + GOC:TermGenie + + + + + downregulation of lens fibre cell differentiation + GOC:TermGenie + + + + + negative regulation of lens fibre cell differentiation + GOC:TermGenie + + + + + inhibition of lens fiber cell differentiation + GOC:TermGenie + + + + + inhibition of lens fibre cell differentiation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of lens fiber cell differentiation. + mr + 2014-03-03T23:20:12Z + positive regulation of lens fibre cell differentiation + up regulation of lens fiber cell differentiation + up regulation of lens fibre cell differentiation + up-regulation of lens fiber cell differentiation + up-regulation of lens fibre cell differentiation + upregulation of lens fiber cell differentiation + upregulation of lens fibre cell differentiation + activation of lens fiber cell differentiation + activation of lens fibre cell differentiation + biological_process + GO:1902748 + positive regulation of lens fiber cell differentiation + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that activates or increases the frequency, rate or extent of lens fiber cell differentiation. + GOC:TermGenie + GOC:mr + GO_REF:0000058 + PMID:17592637 + + + + + positive regulation of lens fibre cell differentiation + GOC:TermGenie + + + + + up regulation of lens fiber cell differentiation + GOC:TermGenie + + + + + up regulation of lens fibre cell differentiation + GOC:TermGenie + + + + + up-regulation of lens fiber cell differentiation + GOC:TermGenie + + + + + up-regulation of lens fibre cell differentiation + GOC:TermGenie + + + + + upregulation of lens fiber cell differentiation + GOC:TermGenie + + + + + upregulation of lens fibre cell differentiation + GOC:TermGenie + + + + + activation of lens fiber cell differentiation + GOC:TermGenie + + + + + activation of lens fibre cell differentiation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of chondrocyte development. + mr + 2014-03-07T17:45:55Z + up regulation of chondrocyte development + up-regulation of chondrocyte development + upregulation of chondrocyte development + activation of chondrocyte development + biological_process + GO:1902761 + positive regulation of chondrocyte development + + + + + Any process that activates or increases the frequency, rate or extent of chondrocyte development. + GOC:TermGenie + GOC:mr + GO_REF:0000058 + PMID:16575901 + + + + + up regulation of chondrocyte development + GOC:TermGenie + + + + + up-regulation of chondrocyte development + GOC:TermGenie + + + + + upregulation of chondrocyte development + GOC:TermGenie + + + + + activation of chondrocyte development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of skeletal muscle fiber differentiation. + mr + 2014-03-26T21:18:26Z + biological_process + GO:1902809 + regulation of skeletal muscle fiber differentiation + + + + + Any process that modulates the frequency, rate or extent of skeletal muscle fiber differentiation. + GOC:TermGenie + GOC:mr + GO_REF:0000058 + PMID:17879321 + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle fiber differentiation. + mr + 2014-03-26T21:18:32Z + down regulation of skeletal muscle fiber differentiation + down-regulation of skeletal muscle fiber differentiation + downregulation of skeletal muscle fiber differentiation + inhibition of skeletal muscle fiber differentiation + biological_process + GO:1902810 + negative regulation of skeletal muscle fiber differentiation + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle fiber differentiation. + GOC:TermGenie + GOC:mr + GO_REF:0000058 + PMID:17879321 + + + + + down regulation of skeletal muscle fiber differentiation + GOC:TermGenie + + + + + down-regulation of skeletal muscle fiber differentiation + GOC:TermGenie + + + + + downregulation of skeletal muscle fiber differentiation + GOC:TermGenie + + + + + inhibition of skeletal muscle fiber differentiation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of skeletal muscle fiber differentiation. + mr + 2014-03-26T21:18:38Z + up regulation of skeletal muscle fiber differentiation + up-regulation of skeletal muscle fiber differentiation + upregulation of skeletal muscle fiber differentiation + activation of skeletal muscle fiber differentiation + biological_process + GO:1902811 + positive regulation of skeletal muscle fiber differentiation + + + + + Any process that activates or increases the frequency, rate or extent of skeletal muscle fiber differentiation. + GOC:TermGenie + GOC:mr + GO_REF:0000058 + PMID:17879321 + + + + + up regulation of skeletal muscle fiber differentiation + GOC:TermGenie + + + + + up-regulation of skeletal muscle fiber differentiation + GOC:TermGenie + + + + + upregulation of skeletal muscle fiber differentiation + GOC:TermGenie + + + + + activation of skeletal muscle fiber differentiation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of protein localization to microtubule. + tb + 2014-03-27T22:07:12Z + regulation of protein localisation to microtubule + biological_process + GO:1902816 + regulation of protein localization to microtubule + + + + + Any process that modulates the frequency, rate or extent of protein localization to microtubule. + GOC:TermGenie + GOC:vw + GO_REF:0000058 + PMID:23087209 + + + + + regulation of protein localisation to microtubule + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to microtubule. + tb + 2014-03-27T22:07:18Z + down regulation of protein localisation to microtubule + down regulation of protein localization to microtubule + down-regulation of protein localisation to microtubule + down-regulation of protein localization to microtubule + downregulation of protein localisation to microtubule + downregulation of protein localization to microtubule + negative regulation of protein localisation to microtubule + inhibition of protein localisation to microtubule + inhibition of protein localization to microtubule + biological_process + GO:1902817 + negative regulation of protein localization to microtubule + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to microtubule. + GOC:TermGenie + GOC:vw + GO_REF:0000058 + PMID:23087209 + + + + + down regulation of protein localisation to microtubule + GOC:TermGenie + + + + + down regulation of protein localization to microtubule + GOC:TermGenie + + + + + down-regulation of protein localisation to microtubule + GOC:TermGenie + + + + + down-regulation of protein localization to microtubule + GOC:TermGenie + + + + + downregulation of protein localisation to microtubule + GOC:TermGenie + + + + + downregulation of protein localization to microtubule + GOC:TermGenie + + + + + negative regulation of protein localisation to microtubule + GOC:TermGenie + + + + + inhibition of protein localisation to microtubule + GOC:TermGenie + + + + + inhibition of protein localization to microtubule + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in dorsal spinal cord. + mr + 2014-03-31T17:42:50Z + down regulation of cell proliferation in dorsal spinal cord + down-regulation of cell proliferation in dorsal spinal cord + downregulation of cell proliferation in dorsal spinal cord + inhibition of cell proliferation in dorsal spinal cord + biological_process + GO:1902832 + negative regulation of cell proliferation in dorsal spinal cord + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in dorsal spinal cord. + GOC:TermGenie + GOC:mr + GO_REF:0000058 + PMID:21730158 + + + + + down regulation of cell proliferation in dorsal spinal cord + GOC:TermGenie + + + + + down-regulation of cell proliferation in dorsal spinal cord + GOC:TermGenie + + + + + downregulation of cell proliferation in dorsal spinal cord + GOC:TermGenie + + + + + inhibition of cell proliferation in dorsal spinal cord + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of cell proliferation in dorsal spinal cord. + mr + 2014-03-31T17:43:33Z + up regulation of cell proliferation in dorsal spinal cord + up-regulation of cell proliferation in dorsal spinal cord + upregulation of cell proliferation in dorsal spinal cord + activation of cell proliferation in dorsal spinal cord + biological_process + GO:1902833 + positive regulation of cell proliferation in dorsal spinal cord + + + + + Any process that activates or increases the frequency, rate or extent of cell proliferation in dorsal spinal cord. + GOC:TermGenie + GOC:mr + GO_REF:0000058 + PMID:21730158 + + + + + up regulation of cell proliferation in dorsal spinal cord + GOC:TermGenie + + + + + up-regulation of cell proliferation in dorsal spinal cord + GOC:TermGenie + + + + + upregulation of cell proliferation in dorsal spinal cord + GOC:TermGenie + + + + + activation of cell proliferation in dorsal spinal cord + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of nuclear migration along microtubule. + vw + 2014-04-01T13:50:23Z + regulation of nuclear movement, microtubule-mediated + regulation of nucleus migration + regulation of microtubule cytoskeleton-dependent nuclear positioning + regulation of microtubule cytoskeleton-dependent nucleus positioning + regulation of microtubule-dependent nuclear positioning + regulation of microtubule-dependent nucleus positioning + regulation of microtubule-mediated nuclear migration + regulation of nuclear migration, microtubule-mediated + regulation of transport of nucleus by microtubules + regulation of transport of nucleus, microtubule-mediated + biological_process + GO:1902838 + regulation of nuclear migration along microtubule + + + + + Any process that modulates the frequency, rate or extent of nuclear migration along microtubule. + GOC:TermGenie + GO_REF:0000058 + PMID:23087209 + + + + + regulation of nuclear movement, microtubule-mediated + GOC:TermGenie + + + + + regulation of nucleus migration + GOC:TermGenie + + + + + regulation of microtubule cytoskeleton-dependent nuclear positioning + GOC:TermGenie + + + + + regulation of microtubule cytoskeleton-dependent nucleus positioning + GOC:TermGenie + + + + + regulation of microtubule-dependent nuclear positioning + GOC:TermGenie + + + + + regulation of microtubule-dependent nucleus positioning + GOC:TermGenie + + + + + regulation of microtubule-mediated nuclear migration + GOC:TermGenie + + + + + regulation of nuclear migration, microtubule-mediated + GOC:TermGenie + + + + + regulation of transport of nucleus by microtubules + GOC:TermGenie + + + + + regulation of transport of nucleus, microtubule-mediated + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of nuclear migration along microtubule. + vw + 2014-04-01T13:50:29Z + down regulation of microtubule cytoskeleton-dependent nuclear positioning + down regulation of microtubule cytoskeleton-dependent nucleus positioning + down regulation of microtubule-dependent nuclear positioning + down regulation of microtubule-dependent nucleus positioning + down regulation of microtubule-mediated nuclear migration + down regulation of nuclear migration along microtubule + down regulation of nuclear migration, microtubule-mediated + down regulation of transport of nucleus by microtubules + down regulation of transport of nucleus, microtubule-mediated + down-regulation of microtubule cytoskeleton-dependent nuclear positioning + down-regulation of microtubule cytoskeleton-dependent nucleus positioning + down-regulation of microtubule-dependent nuclear positioning + down-regulation of microtubule-dependent nucleus positioning + down-regulation of microtubule-mediated nuclear migration + down-regulation of nuclear migration along microtubule + down-regulation of nuclear migration, microtubule-mediated + down-regulation of transport of nucleus by microtubules + down-regulation of transport of nucleus, microtubule-mediated + downregulation of microtubule cytoskeleton-dependent nuclear positioning + downregulation of microtubule cytoskeleton-dependent nucleus positioning + downregulation of microtubule-dependent nuclear positioning + downregulation of microtubule-dependent nucleus positioning + downregulation of microtubule-mediated nuclear migration + downregulation of nuclear migration along microtubule + downregulation of nuclear migration, microtubule-mediated + downregulation of transport of nucleus by microtubules + downregulation of transport of nucleus, microtubule-mediated + negative regulation of microtubule cytoskeleton-dependent nuclear positioning + negative regulation of microtubule cytoskeleton-dependent nucleus positioning + negative regulation of microtubule-dependent nuclear positioning + negative regulation of microtubule-dependent nucleus positioning + negative regulation of microtubule-mediated nuclear migration + negative regulation of nuclear migration, microtubule-mediated + negative regulation of transport of nucleus by microtubules + negative regulation of transport of nucleus, microtubule-mediated + inhibition of microtubule cytoskeleton-dependent nuclear positioning + inhibition of microtubule cytoskeleton-dependent nucleus positioning + inhibition of microtubule-dependent nuclear positioning + inhibition of microtubule-dependent nucleus positioning + inhibition of microtubule-mediated nuclear migration + inhibition of nuclear migration along microtubule + inhibition of nuclear migration, microtubule-mediated + inhibition of transport of nucleus by microtubules + inhibition of transport of nucleus, microtubule-mediated + biological_process + GO:1902839 + negative regulation of nuclear migration along microtubule + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of nuclear migration along microtubule. + GOC:TermGenie + GO_REF:0000058 + PMID:23087209 + + + + + down regulation of microtubule cytoskeleton-dependent nuclear positioning + GOC:TermGenie + + + + + down regulation of microtubule cytoskeleton-dependent nucleus positioning + GOC:TermGenie + + + + + down regulation of microtubule-dependent nuclear positioning + GOC:TermGenie + + + + + down regulation of microtubule-dependent nucleus positioning + GOC:TermGenie + + + + + down regulation of microtubule-mediated nuclear migration + GOC:TermGenie + + + + + down regulation of nuclear migration along microtubule + GOC:TermGenie + + + + + down regulation of nuclear migration, microtubule-mediated + GOC:TermGenie + + + + + down regulation of transport of nucleus by microtubules + GOC:TermGenie + + + + + down regulation of transport of nucleus, microtubule-mediated + GOC:TermGenie + + + + + down-regulation of microtubule cytoskeleton-dependent nuclear positioning + GOC:TermGenie + + + + + down-regulation of microtubule cytoskeleton-dependent nucleus positioning + GOC:TermGenie + + + + + down-regulation of microtubule-dependent nuclear positioning + GOC:TermGenie + + + + + down-regulation of microtubule-dependent nucleus positioning + GOC:TermGenie + + + + + down-regulation of microtubule-mediated nuclear migration + GOC:TermGenie + + + + + down-regulation of nuclear migration along microtubule + GOC:TermGenie + + + + + down-regulation of nuclear migration, microtubule-mediated + GOC:TermGenie + + + + + down-regulation of transport of nucleus by microtubules + GOC:TermGenie + + + + + down-regulation of transport of nucleus, microtubule-mediated + GOC:TermGenie + + + + + downregulation of microtubule cytoskeleton-dependent nuclear positioning + GOC:TermGenie + + + + + downregulation of microtubule cytoskeleton-dependent nucleus positioning + GOC:TermGenie + + + + + downregulation of microtubule-dependent nuclear positioning + GOC:TermGenie + + + + + downregulation of microtubule-dependent nucleus positioning + GOC:TermGenie + + + + + downregulation of microtubule-mediated nuclear migration + GOC:TermGenie + + + + + downregulation of nuclear migration along microtubule + GOC:TermGenie + + + + + downregulation of nuclear migration, microtubule-mediated + GOC:TermGenie + + + + + downregulation of transport of nucleus by microtubules + GOC:TermGenie + + + + + downregulation of transport of nucleus, microtubule-mediated + GOC:TermGenie + + + + + negative regulation of microtubule cytoskeleton-dependent nuclear positioning + GOC:TermGenie + + + + + negative regulation of microtubule cytoskeleton-dependent nucleus positioning + GOC:TermGenie + + + + + negative regulation of microtubule-dependent nuclear positioning + GOC:TermGenie + + + + + negative regulation of microtubule-dependent nucleus positioning + GOC:TermGenie + + + + + negative regulation of microtubule-mediated nuclear migration + GOC:TermGenie + + + + + negative regulation of nuclear migration, microtubule-mediated + GOC:TermGenie + + + + + negative regulation of transport of nucleus by microtubules + GOC:TermGenie + + + + + negative regulation of transport of nucleus, microtubule-mediated + GOC:TermGenie + + + + + inhibition of microtubule cytoskeleton-dependent nuclear positioning + GOC:TermGenie + + + + + inhibition of microtubule cytoskeleton-dependent nucleus positioning + GOC:TermGenie + + + + + inhibition of microtubule-dependent nuclear positioning + GOC:TermGenie + + + + + inhibition of microtubule-dependent nucleus positioning + GOC:TermGenie + + + + + inhibition of microtubule-mediated nuclear migration + GOC:TermGenie + + + + + inhibition of nuclear migration along microtubule + GOC:TermGenie + + + + + inhibition of nuclear migration, microtubule-mediated + GOC:TermGenie + + + + + inhibition of transport of nucleus by microtubules + GOC:TermGenie + + + + + inhibition of transport of nucleus, microtubule-mediated + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of nuclear migration along microtubule. + vw + 2014-04-01T13:50:35Z + positive regulation of microtubule cytoskeleton-dependent nuclear positioning + positive regulation of microtubule cytoskeleton-dependent nucleus positioning + positive regulation of microtubule-dependent nuclear positioning + positive regulation of microtubule-dependent nucleus positioning + positive regulation of microtubule-mediated nuclear migration + positive regulation of nuclear migration, microtubule-mediated + positive regulation of transport of nucleus by microtubules + positive regulation of transport of nucleus, microtubule-mediated + up regulation of microtubule cytoskeleton-dependent nuclear positioning + up regulation of microtubule cytoskeleton-dependent nucleus positioning + up regulation of microtubule-dependent nuclear positioning + up regulation of microtubule-dependent nucleus positioning + up regulation of microtubule-mediated nuclear migration + up regulation of nuclear migration along microtubule + up regulation of nuclear migration, microtubule-mediated + up regulation of transport of nucleus by microtubules + up regulation of transport of nucleus, microtubule-mediated + up-regulation of microtubule cytoskeleton-dependent nuclear positioning + up-regulation of microtubule cytoskeleton-dependent nucleus positioning + up-regulation of microtubule-dependent nuclear positioning + up-regulation of microtubule-dependent nucleus positioning + up-regulation of microtubule-mediated nuclear migration + up-regulation of nuclear migration along microtubule + up-regulation of nuclear migration, microtubule-mediated + up-regulation of transport of nucleus by microtubules + up-regulation of transport of nucleus, microtubule-mediated + upregulation of microtubule cytoskeleton-dependent nuclear positioning + upregulation of microtubule cytoskeleton-dependent nucleus positioning + upregulation of microtubule-dependent nuclear positioning + upregulation of microtubule-dependent nucleus positioning + upregulation of microtubule-mediated nuclear migration + upregulation of nuclear migration along microtubule + upregulation of nuclear migration, microtubule-mediated + upregulation of transport of nucleus by microtubules + upregulation of transport of nucleus, microtubule-mediated + activation of microtubule cytoskeleton-dependent nuclear positioning + activation of microtubule cytoskeleton-dependent nucleus positioning + activation of microtubule-dependent nuclear positioning + activation of microtubule-dependent nucleus positioning + activation of microtubule-mediated nuclear migration + activation of nuclear migration along microtubule + activation of nuclear migration, microtubule-mediated + activation of transport of nucleus by microtubules + activation of transport of nucleus, microtubule-mediated + biological_process + GO:1902840 + positive regulation of nuclear migration along microtubule + + + + + Any process that activates or increases the frequency, rate or extent of nuclear migration along microtubule. + GOC:TermGenie + GO_REF:0000058 + PMID:23087209 + + + + + positive regulation of microtubule cytoskeleton-dependent nuclear positioning + GOC:TermGenie + + + + + positive regulation of microtubule cytoskeleton-dependent nucleus positioning + GOC:TermGenie + + + + + positive regulation of microtubule-dependent nuclear positioning + GOC:TermGenie + + + + + positive regulation of microtubule-dependent nucleus positioning + GOC:TermGenie + + + + + positive regulation of microtubule-mediated nuclear migration + GOC:TermGenie + + + + + positive regulation of nuclear migration, microtubule-mediated + GOC:TermGenie + + + + + positive regulation of transport of nucleus by microtubules + GOC:TermGenie + + + + + positive regulation of transport of nucleus, microtubule-mediated + GOC:TermGenie + + + + + up regulation of microtubule cytoskeleton-dependent nuclear positioning + GOC:TermGenie + + + + + up regulation of microtubule cytoskeleton-dependent nucleus positioning + GOC:TermGenie + + + + + up regulation of microtubule-dependent nuclear positioning + GOC:TermGenie + + + + + up regulation of microtubule-dependent nucleus positioning + GOC:TermGenie + + + + + up regulation of microtubule-mediated nuclear migration + GOC:TermGenie + + + + + up regulation of nuclear migration along microtubule + GOC:TermGenie + + + + + up regulation of nuclear migration, microtubule-mediated + GOC:TermGenie + + + + + up regulation of transport of nucleus by microtubules + GOC:TermGenie + + + + + up regulation of transport of nucleus, microtubule-mediated + GOC:TermGenie + + + + + up-regulation of microtubule cytoskeleton-dependent nuclear positioning + GOC:TermGenie + + + + + up-regulation of microtubule cytoskeleton-dependent nucleus positioning + GOC:TermGenie + + + + + up-regulation of microtubule-dependent nuclear positioning + GOC:TermGenie + + + + + up-regulation of microtubule-dependent nucleus positioning + GOC:TermGenie + + + + + up-regulation of microtubule-mediated nuclear migration + GOC:TermGenie + + + + + up-regulation of nuclear migration along microtubule + GOC:TermGenie + + + + + up-regulation of nuclear migration, microtubule-mediated + GOC:TermGenie + + + + + up-regulation of transport of nucleus by microtubules + GOC:TermGenie + + + + + up-regulation of transport of nucleus, microtubule-mediated + GOC:TermGenie + + + + + upregulation of microtubule cytoskeleton-dependent nuclear positioning + GOC:TermGenie + + + + + upregulation of microtubule cytoskeleton-dependent nucleus positioning + GOC:TermGenie + + + + + upregulation of microtubule-dependent nuclear positioning + GOC:TermGenie + + + + + upregulation of microtubule-dependent nucleus positioning + GOC:TermGenie + + + + + upregulation of microtubule-mediated nuclear migration + GOC:TermGenie + + + + + upregulation of nuclear migration along microtubule + GOC:TermGenie + + + + + upregulation of nuclear migration, microtubule-mediated + GOC:TermGenie + + + + + upregulation of transport of nucleus by microtubules + GOC:TermGenie + + + + + upregulation of transport of nucleus, microtubule-mediated + GOC:TermGenie + + + + + activation of microtubule cytoskeleton-dependent nuclear positioning + GOC:TermGenie + + + + + activation of microtubule cytoskeleton-dependent nucleus positioning + GOC:TermGenie + + + + + activation of microtubule-dependent nuclear positioning + GOC:TermGenie + + + + + activation of microtubule-dependent nucleus positioning + GOC:TermGenie + + + + + activation of microtubule-mediated nuclear migration + GOC:TermGenie + + + + + activation of nuclear migration along microtubule + GOC:TermGenie + + + + + activation of nuclear migration, microtubule-mediated + GOC:TermGenie + + + + + activation of transport of nucleus by microtubules + GOC:TermGenie + + + + + activation of transport of nucleus, microtubule-mediated + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of non-motile cilium assembly. + kmv + 2014-04-02T15:41:57Z + biological_process + regulation of immotile primary cilium assembly + regulation of nonmotile primary cilia assembly + regulation of nonmotile primary cilium assembly + regulation of sensory cilium assembly + regulation of sensory cilium biogenesis + GO:1902855 + regulation of non-motile cilium assembly + + + + + Any process that modulates the frequency, rate or extent of non-motile cilium assembly. + GOC:TermGenie + GOC:cilia + GOC:kmv + GO_REF:0000058 + PMID:23807208 + + + + + regulation of immotile primary cilium assembly + GOC:TermGenie + + + + + regulation of nonmotile primary cilia assembly + GOC:TermGenie + + + + + regulation of sensory cilium assembly + GOC:TermGenie + + + + + regulation of sensory cilium biogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of non-motile cilium assembly. + kmv + 2014-04-02T15:42:17Z + inhibition of immotile primary cilium assembly + inhibition of nonmotile primary cilium assembly + inhibition of sensory cilium assembly + biological_process + down regulation of immotile primary cilium assembly + down regulation of nonmotile primary cilia assembly + down regulation of nonmotile primary cilium assembly + down regulation of sensory cilium assembly + down regulation of sensory cilium biogenesis + down-regulation of immotile primary cilium assembly + down-regulation of nonmotile primary cilia assembly + down-regulation of nonmotile primary cilium assembly + down-regulation of sensory cilium assembly + down-regulation of sensory cilium biogenesis + downregulation of immotile primary cilium assembly + downregulation of nonmotile primary cilia assembly + downregulation of nonmotile primary cilium assembly + downregulation of sensory cilium assembly + downregulation of sensory cilium biogenesis + inhibition of nonmotile primary cilia assembly + inhibition of sensory cilium biogenesis + negative regulation of immotile primary cilium assembly + negative regulation of nonmotile primary cilia assembly + negative regulation of nonmotile primary cilium assembly + negative regulation of sensory cilium assembly + negative regulation of sensory cilium biogenesis + GO:1902856 + negative regulation of non-motile cilium assembly + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of non-motile cilium assembly. + GOC:TermGenie + GOC:cilia + GOC:kmv + GO_REF:0000058 + PMID:23807208 + + + + + inhibition of immotile primary cilium assembly + GOC:TermGenie + + + + + inhibition of nonmotile primary cilium assembly + GOC:TermGenie + + + + + inhibition of sensory cilium assembly + GOC:TermGenie + + + + + down regulation of immotile primary cilium assembly + GOC:TermGenie + + + + + down regulation of nonmotile primary cilia assembly + GOC:TermGenie + + + + + down regulation of nonmotile primary cilium assembly + GOC:TermGenie + + + + + down regulation of sensory cilium assembly + GOC:TermGenie + + + + + down regulation of sensory cilium biogenesis + GOC:TermGenie + + + + + down-regulation of immotile primary cilium assembly + GOC:TermGenie + + + + + down-regulation of nonmotile primary cilia assembly + GOC:TermGenie + + + + + down-regulation of nonmotile primary cilium assembly + GOC:TermGenie + + + + + down-regulation of sensory cilium assembly + GOC:TermGenie + + + + + down-regulation of sensory cilium biogenesis + GOC:TermGenie + + + + + downregulation of immotile primary cilium assembly + GOC:TermGenie + + + + + downregulation of nonmotile primary cilia assembly + GOC:TermGenie + + + + + downregulation of nonmotile primary cilium assembly + GOC:TermGenie + + + + + downregulation of sensory cilium assembly + GOC:TermGenie + + + + + downregulation of sensory cilium biogenesis + GOC:TermGenie + + + + + inhibition of nonmotile primary cilia assembly + GOC:TermGenie + + + + + inhibition of sensory cilium biogenesis + GOC:TermGenie + + + + + negative regulation of immotile primary cilium assembly + GOC:TermGenie + + + + + negative regulation of nonmotile primary cilia assembly + GOC:TermGenie + + + + + negative regulation of sensory cilium assembly + GOC:TermGenie + + + + + negative regulation of sensory cilium biogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of non-motile cilium assembly. + kmv + 2014-04-02T15:42:31Z + activation of immotile primary cilium assembly + activation of nonmotile primary cilium assembly + activation of sensory cilium assembly + biological_process + activation of nonmotile primary cilia assembly + activation of sensory cilium biogenesis + positive regulation of immotile primary cilium assembly + positive regulation of nonmotile primary cilia assembly + positive regulation of nonmotile primary cilium assembly + positive regulation of sensory cilium assembly + positive regulation of sensory cilium biogenesis + up regulation of immotile primary cilium assembly + up regulation of nonmotile primary cilia assembly + up regulation of nonmotile primary cilium assembly + up regulation of sensory cilium assembly + up regulation of sensory cilium biogenesis + up-regulation of immotile primary cilium assembly + up-regulation of nonmotile primary cilia assembly + up-regulation of nonmotile primary cilium assembly + up-regulation of sensory cilium assembly + up-regulation of sensory cilium biogenesis + upregulation of immotile primary cilium assembly + upregulation of nonmotile primary cilia assembly + upregulation of nonmotile primary cilium assembly + upregulation of sensory cilium assembly + upregulation of sensory cilium biogenesis + GO:1902857 + positive regulation of non-motile cilium assembly + + + + + Any process that activates or increases the frequency, rate or extent of non-motile cilium assembly. + GOC:TermGenie + GOC:cilia + GOC:kmv + GO_REF:0000058 + PMID:23807208 + + + + + activation of immotile primary cilium assembly + GOC:TermGenie + + + + + activation of nonmotile primary cilium assembly + GOC:TermGenie + + + + + activation of sensory cilium assembly + GOC:TermGenie + + + + + activation of nonmotile primary cilia assembly + GOC:TermGenie + + + + + activation of sensory cilium biogenesis + GOC:TermGenie + + + + + positive regulation of immotile primary cilium assembly + GOC:TermGenie + + + + + positive regulation of nonmotile primary cilia assembly + GOC:TermGenie + + + + + positive regulation of sensory cilium assembly + GOC:TermGenie + + + + + positive regulation of sensory cilium biogenesis + GOC:TermGenie + + + + + up regulation of immotile primary cilium assembly + GOC:TermGenie + + + + + up regulation of nonmotile primary cilia assembly + GOC:TermGenie + + + + + up regulation of nonmotile primary cilium assembly + GOC:TermGenie + + + + + up regulation of sensory cilium assembly + GOC:TermGenie + + + + + up regulation of sensory cilium biogenesis + GOC:TermGenie + + + + + up-regulation of immotile primary cilium assembly + GOC:TermGenie + + + + + up-regulation of nonmotile primary cilia assembly + GOC:TermGenie + + + + + up-regulation of nonmotile primary cilium assembly + GOC:TermGenie + + + + + up-regulation of sensory cilium assembly + GOC:TermGenie + + + + + up-regulation of sensory cilium biogenesis + GOC:TermGenie + + + + + upregulation of immotile primary cilium assembly + GOC:TermGenie + + + + + upregulation of nonmotile primary cilia assembly + GOC:TermGenie + + + + + upregulation of nonmotile primary cilium assembly + GOC:TermGenie + + + + + upregulation of sensory cilium assembly + GOC:TermGenie + + + + + upregulation of sensory cilium biogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of embryonic camera-type eye development. + mr + 2014-04-03T15:24:00Z + regulation of embryonic eye development + biological_process + GO:1902863 + regulation of embryonic camera-type eye development + + + + + Any process that modulates the frequency, rate or extent of embryonic camera-type eye development. + GOC:TermGenie + GOC:mr + GO_REF:0000058 + PMID:16872597 + + + + + regulation of embryonic eye development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of embryonic camera-type eye development. + mr + 2014-04-03T15:24:06Z + down regulation of embryonic camera-type eye development + down regulation of embryonic eye development + down-regulation of embryonic camera-type eye development + down-regulation of embryonic eye development + downregulation of embryonic camera-type eye development + downregulation of embryonic eye development + negative regulation of embryonic eye development + inhibition of embryonic camera-type eye development + inhibition of embryonic eye development + biological_process + GO:1902864 + negative regulation of embryonic camera-type eye development + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of embryonic camera-type eye development. + GOC:TermGenie + GOC:mr + GO_REF:0000058 + PMID:16872597 + + + + + down regulation of embryonic camera-type eye development + GOC:TermGenie + + + + + down regulation of embryonic eye development + GOC:TermGenie + + + + + down-regulation of embryonic camera-type eye development + GOC:TermGenie + + + + + down-regulation of embryonic eye development + GOC:TermGenie + + + + + downregulation of embryonic camera-type eye development + GOC:TermGenie + + + + + downregulation of embryonic eye development + GOC:TermGenie + + + + + negative regulation of embryonic eye development + GOC:TermGenie + + + + + inhibition of embryonic camera-type eye development + GOC:TermGenie + + + + + inhibition of embryonic eye development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of embryonic camera-type eye development. + mr + 2014-04-03T15:24:12Z + positive regulation of embryonic eye development + up regulation of embryonic camera-type eye development + up regulation of embryonic eye development + up-regulation of embryonic camera-type eye development + up-regulation of embryonic eye development + upregulation of embryonic camera-type eye development + upregulation of embryonic eye development + activation of embryonic camera-type eye development + activation of embryonic eye development + biological_process + GO:1902865 + positive regulation of embryonic camera-type eye development + + + + + Any process that activates or increases the frequency, rate or extent of embryonic camera-type eye development. + GOC:TermGenie + GOC:mr + GO_REF:0000058 + PMID:16872597 + + + + + positive regulation of embryonic eye development + GOC:TermGenie + + + + + up regulation of embryonic camera-type eye development + GOC:TermGenie + + + + + up regulation of embryonic eye development + GOC:TermGenie + + + + + up-regulation of embryonic camera-type eye development + GOC:TermGenie + + + + + up-regulation of embryonic eye development + GOC:TermGenie + + + + + upregulation of embryonic camera-type eye development + GOC:TermGenie + + + + + upregulation of embryonic eye development + GOC:TermGenie + + + + + activation of embryonic camera-type eye development + GOC:TermGenie + + + + + activation of embryonic eye development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of retina development in camera-type eye. + mr + 2014-04-03T15:24:17Z + regulation of retina development in camera-style eye + biological_process + regulation of retinal development + GO:1902866 + regulation of retina development in camera-type eye + + + + + Any process that modulates the frequency, rate or extent of retina development in camera-type eye. + GOC:TermGenie + GOC:mr + GO_REF:0000058 + PMID:16872597 + + + + + regulation of retina development in camera-style eye + GOC:TermGenie + + + + + regulation of retinal development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of retina development in camera-type eye. + mr + 2014-04-03T15:24:23Z + down regulation of retina development in camera-style eye + down regulation of retina development in camera-type eye + down-regulation of retina development in camera-style eye + down-regulation of retina development in camera-type eye + downregulation of retina development in camera-style eye + downregulation of retina development in camera-type eye + negative regulation of retina development in camera-style eye + inhibition of retina development in camera-style eye + inhibition of retina development in camera-type eye + biological_process + down regulation of retinal development + down-regulation of retinal development + downregulation of retinal development + inhibition of retinal development + negative regulation of retinal development + GO:1902867 + negative regulation of retina development in camera-type eye + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of retina development in camera-type eye. + GOC:TermGenie + GOC:mr + GO_REF:0000058 + PMID:16872597 + + + + + down regulation of retina development in camera-style eye + GOC:TermGenie + + + + + down regulation of retina development in camera-type eye + GOC:TermGenie + + + + + down-regulation of retina development in camera-style eye + GOC:TermGenie + + + + + down-regulation of retina development in camera-type eye + GOC:TermGenie + + + + + downregulation of retina development in camera-style eye + GOC:TermGenie + + + + + downregulation of retina development in camera-type eye + GOC:TermGenie + + + + + negative regulation of retina development in camera-style eye + GOC:TermGenie + + + + + inhibition of retina development in camera-style eye + GOC:TermGenie + + + + + inhibition of retina development in camera-type eye + GOC:TermGenie + + + + + down regulation of retinal development + GOC:TermGenie + + + + + down-regulation of retinal development + GOC:TermGenie + + + + + downregulation of retinal development + GOC:TermGenie + + + + + inhibition of retinal development + GOC:TermGenie + + + + + negative regulation of retinal development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of retina development in camera-type eye. + mr + 2014-04-03T15:24:29Z + positive regulation of retina development in camera-style eye + up regulation of retina development in camera-style eye + up regulation of retina development in camera-type eye + up-regulation of retina development in camera-style eye + up-regulation of retina development in camera-type eye + upregulation of retina development in camera-style eye + upregulation of retina development in camera-type eye + activation of retina development in camera-style eye + activation of retina development in camera-type eye + biological_process + activation of retinal development + positive regulation of retinal development + up regulation of retinal development + up-regulation of retinal development + upregulation of retinal development + GO:1902868 + positive regulation of retina development in camera-type eye + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that activates or increases the frequency, rate or extent of retina development in camera-type eye. + GOC:TermGenie + GOC:mr + GO_REF:0000058 + PMID:16872597 + + + + + positive regulation of retina development in camera-style eye + GOC:TermGenie + + + + + up regulation of retina development in camera-style eye + GOC:TermGenie + + + + + up regulation of retina development in camera-type eye + GOC:TermGenie + + + + + up-regulation of retina development in camera-style eye + GOC:TermGenie + + + + + up-regulation of retina development in camera-type eye + GOC:TermGenie + + + + + upregulation of retina development in camera-style eye + GOC:TermGenie + + + + + upregulation of retina development in camera-type eye + GOC:TermGenie + + + + + activation of retina development in camera-style eye + GOC:TermGenie + + + + + activation of retina development in camera-type eye + GOC:TermGenie + + + + + activation of retinal development + GOC:TermGenie + + + + + positive regulation of retinal development + GOC:TermGenie + + + + + up regulation of retinal development + GOC:TermGenie + + + + + up-regulation of retinal development + GOC:TermGenie + + + + + upregulation of retinal development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of amacrine cell differentiation. + mr + 2014-04-03T15:24:35Z + regulation of amacrine neuron differentiation + biological_process + GO:1902869 + regulation of amacrine cell differentiation + + + + + Any process that modulates the frequency, rate or extent of amacrine cell differentiation. + GOC:TermGenie + GOC:mr + GO_REF:0000058 + PMID:16872597 + + + + + regulation of amacrine neuron differentiation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of amacrine cell differentiation. + mr + 2014-04-03T15:24:40Z + down regulation of amacrine cell differentiation + down regulation of amacrine neuron differentiation + down-regulation of amacrine cell differentiation + down-regulation of amacrine neuron differentiation + downregulation of amacrine cell differentiation + downregulation of amacrine neuron differentiation + negative regulation of amacrine neuron differentiation + inhibition of amacrine cell differentiation + inhibition of amacrine neuron differentiation + biological_process + GO:1902870 + negative regulation of amacrine cell differentiation + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of amacrine cell differentiation. + GOC:TermGenie + GOC:mr + GO_REF:0000058 + PMID:16872597 + + + + + down regulation of amacrine cell differentiation + GOC:TermGenie + + + + + down regulation of amacrine neuron differentiation + GOC:TermGenie + + + + + down-regulation of amacrine cell differentiation + GOC:TermGenie + + + + + down-regulation of amacrine neuron differentiation + GOC:TermGenie + + + + + downregulation of amacrine cell differentiation + GOC:TermGenie + + + + + downregulation of amacrine neuron differentiation + GOC:TermGenie + + + + + negative regulation of amacrine neuron differentiation + GOC:TermGenie + + + + + inhibition of amacrine cell differentiation + GOC:TermGenie + + + + + inhibition of amacrine neuron differentiation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of amacrine cell differentiation. + mr + 2014-04-03T15:24:46Z + positive regulation of amacrine neuron differentiation + up regulation of amacrine cell differentiation + up regulation of amacrine neuron differentiation + up-regulation of amacrine cell differentiation + up-regulation of amacrine neuron differentiation + upregulation of amacrine cell differentiation + upregulation of amacrine neuron differentiation + activation of amacrine cell differentiation + activation of amacrine neuron differentiation + biological_process + GO:1902871 + positive regulation of amacrine cell differentiation + + + + + Any process that activates or increases the frequency, rate or extent of amacrine cell differentiation. + GOC:TermGenie + GOC:mr + GO_REF:0000058 + PMID:16872597 + + + + + positive regulation of amacrine neuron differentiation + GOC:TermGenie + + + + + up regulation of amacrine cell differentiation + GOC:TermGenie + + + + + up regulation of amacrine neuron differentiation + GOC:TermGenie + + + + + up-regulation of amacrine cell differentiation + GOC:TermGenie + + + + + up-regulation of amacrine neuron differentiation + GOC:TermGenie + + + + + upregulation of amacrine cell differentiation + GOC:TermGenie + + + + + upregulation of amacrine neuron differentiation + GOC:TermGenie + + + + + activation of amacrine cell differentiation + GOC:TermGenie + + + + + activation of amacrine neuron differentiation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of embryonic pattern specification. + mr + 2014-04-03T15:25:15Z + regulation of embryonic pattern biosynthesis + regulation of embryonic pattern formation + biological_process + regulation of ventral/lateral system + GO:1902875 + regulation of embryonic pattern specification + + + + + Any process that modulates the frequency, rate or extent of embryonic pattern specification. + GOC:TermGenie + GOC:mr + GO_REF:0000058 + PMID:16872597 + + + + + regulation of embryonic pattern biosynthesis + GOC:TermGenie + + + + + regulation of embryonic pattern formation + GOC:TermGenie + + + + + regulation of ventral/lateral system + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of embryonic pattern specification. + mr + 2014-04-03T15:25:20Z + down regulation of embryonic pattern specification + down-regulation of embryonic pattern specification + downregulation of embryonic pattern specification + inhibition of embryonic pattern specification + biological_process + down regulation of ventral/lateral system + down-regulation of ventral/lateral system + downregulation of ventral/lateral system + inhibition of ventral/lateral system + negative regulation of ventral/lateral system + GO:1902876 + negative regulation of embryonic pattern specification + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of embryonic pattern specification. + GOC:TermGenie + GOC:mr + GO_REF:0000058 + PMID:16872597 + + + + + down regulation of embryonic pattern specification + GOC:TermGenie + + + + + down-regulation of embryonic pattern specification + GOC:TermGenie + + + + + downregulation of embryonic pattern specification + GOC:TermGenie + + + + + inhibition of embryonic pattern specification + GOC:TermGenie + + + + + down regulation of ventral/lateral system + GOC:TermGenie + + + + + down-regulation of ventral/lateral system + GOC:TermGenie + + + + + downregulation of ventral/lateral system + GOC:TermGenie + + + + + inhibition of ventral/lateral system + GOC:TermGenie + + + + + negative regulation of ventral/lateral system + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of embryonic pattern specification. + mr + 2014-04-03T15:25:26Z + up regulation of embryonic pattern specification + up-regulation of embryonic pattern specification + upregulation of embryonic pattern specification + activation of embryonic pattern specification + biological_process + activation of ventral/lateral system + positive regulation of ventral/lateral system + up regulation of ventral/lateral system + up-regulation of ventral/lateral system + upregulation of ventral/lateral system + GO:1902877 + positive regulation of embryonic pattern specification + + + + + Any process that activates or increases the frequency, rate or extent of embryonic pattern specification. + GOC:TermGenie + GOC:mr + GO_REF:0000058 + PMID:16872597 + + + + + up regulation of embryonic pattern specification + GOC:TermGenie + + + + + up-regulation of embryonic pattern specification + GOC:TermGenie + + + + + upregulation of embryonic pattern specification + GOC:TermGenie + + + + + activation of embryonic pattern specification + GOC:TermGenie + + + + + activation of ventral/lateral system + GOC:TermGenie + + + + + positive regulation of ventral/lateral system + GOC:TermGenie + + + + + up regulation of ventral/lateral system + GOC:TermGenie + + + + + up-regulation of ventral/lateral system + GOC:TermGenie + + + + + upregulation of ventral/lateral system + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of supramolecular fiber organization. + rl + 2014-04-15T16:46:36Z + biological_process + regulation of fibril organisation + GO:1902903 + HSPA8, human, P11142 in PMID:23921388 inferred from direct assay to negatively regulate fibrillation of alpha-Syn in vitro + regulation of supramolecular fiber organization + + + + + Any process that modulates the frequency, rate or extent of supramolecular fiber organization. + GOC:PARL + GOC:TermGenie + GOC:rl + GO_REF:0000058 + PMID:23921388 + + + + + regulation of fibril organisation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of fibril organization. + rl + 2014-04-15T16:46:42Z + inhibition of fibril organisation + inhibition of fibril organization + biological_process + down regulation of fibril organisation + down regulation of fibril organization + down-regulation of fibril organisation + down-regulation of fibril organization + downregulation of fibril organisation + downregulation of fibril organization + negative regulation of fibril organisation + GO:1902904 + HSPA8, human, P11142 in PMID:23921388 inferred from direct assay to negatively regulate fibrillation of alpha-Syn in vitro + negative regulation of supramolecular fiber organization + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of fibril organization. + GOC:PARL + GOC:TermGenie + GOC:rl + GO_REF:0000058 + PMID:23921388 + + + + + inhibition of fibril organisation + GOC:TermGenie + + + + + inhibition of fibril organization + GOC:TermGenie + + + + + down regulation of fibril organisation + GOC:TermGenie + + + + + down regulation of fibril organization + GOC:TermGenie + + + + + down-regulation of fibril organisation + GOC:TermGenie + + + + + down-regulation of fibril organization + GOC:TermGenie + + + + + downregulation of fibril organisation + GOC:TermGenie + + + + + downregulation of fibril organization + GOC:TermGenie + + + + + negative regulation of fibril organisation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of supramolecular fiber organization. + rl + 2014-04-15T16:46:48Z + activation of fibril organisation + activation of fibril organization + biological_process + positive regulation of fibril organisation + up regulation of fibril organisation + up regulation of fibril organization + up-regulation of fibril organisation + up-regulation of fibril organization + upregulation of fibril organisation + upregulation of fibril organization + GO:1902905 + HSPA8, human, P11142 in PMID:23921388 inferred from direct assay to negatively regulate fibrillation of alpha-Syn in vitro + positive regulation of supramolecular fiber organization + + + + + Any process that activates or increases the frequency, rate or extent of supramolecular fiber organization. + GOC:PARL + GOC:TermGenie + GOC:rl + GO_REF:0000058 + PMID:23921388 + + + + + activation of fibril organisation + GOC:TermGenie + + + + + activation of fibril organization + GOC:TermGenie + + + + + positive regulation of fibril organisation + GOC:TermGenie + + + + + up regulation of fibril organisation + GOC:TermGenie + + + + + up regulation of fibril organization + GOC:TermGenie + + + + + up-regulation of fibril organisation + GOC:TermGenie + + + + + up-regulation of fibril organization + GOC:TermGenie + + + + + upregulation of fibril organisation + GOC:TermGenie + + + + + upregulation of fibril organization + GOC:TermGenie + + + + + + + + + + + + + + + + + + + A protein complex which is capable of protein kinase activity. + bhm + 2014-04-17T13:52:40Z + cellular_component + GO:1902911 + An example of this is PKM2 in human (P14618) in PMID:24606918 (inferred from direct assay). + protein kinase complex + + + + + A protein complex which is capable of protein kinase activity. + GOC:TermGenie + GOC:bhm + GO_REF:0000088 + PMID:24606918 + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of bone development. + mr + 2014-05-13T22:41:53Z + biological_process + GO:1903010 + regulation of bone development + + + + + Any process that modulates the frequency, rate or extent of bone development. + GOC:TermGenie + GOC:mr + GO_REF:0000058 + PMID:22510437 + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of bone development. + mr + 2014-05-13T22:42:00Z + down regulation of bone development + down-regulation of bone development + downregulation of bone development + inhibition of bone development + biological_process + GO:1903011 + negative regulation of bone development + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of bone development. + GOC:TermGenie + GOC:mr + GO_REF:0000058 + PMID:22510437 + + + + + down regulation of bone development + GOC:TermGenie + + + + + down-regulation of bone development + GOC:TermGenie + + + + + downregulation of bone development + GOC:TermGenie + + + + + inhibition of bone development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of bone development. + mr + 2014-05-13T22:42:06Z + up regulation of bone development + up-regulation of bone development + upregulation of bone development + activation of bone development + biological_process + GO:1903012 + positive regulation of bone development + + + + + Any process that activates or increases the frequency, rate or extent of bone development. + GOC:TermGenie + GOC:mr + GO_REF:0000058 + PMID:22510437 + + + + + up regulation of bone development + GOC:TermGenie + + + + + up-regulation of bone development + GOC:TermGenie + + + + + upregulation of bone development + GOC:TermGenie + + + + + activation of bone development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of glycoprotein metabolic process. + rl + 2014-05-14T18:44:19Z + regulation of glycoprotein metabolism + biological_process + GO:1903018 + human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) and thus the metabolism of glycoproteins, demonstrated in Figure 4A PMID:23544079, (IDA), the negative regulation term would be applied to this protein + regulation of glycoprotein metabolic process + + + + + Any process that modulates the frequency, rate or extent of glycoprotein metabolic process. + GOC:BHF + GOC:TermGenie + GOC:rl + GO_REF:0000058 + PMID:23544079 + + + + + regulation of glycoprotein metabolism + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of glycoprotein metabolic process. + rl + 2014-05-14T18:44:25Z + down regulation of glycoprotein metabolic process + down regulation of glycoprotein metabolism + down-regulation of glycoprotein metabolic process + down-regulation of glycoprotein metabolism + downregulation of glycoprotein metabolic process + downregulation of glycoprotein metabolism + negative regulation of glycoprotein metabolism + inhibition of glycoprotein metabolic process + inhibition of glycoprotein metabolism + biological_process + GO:1903019 + human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) and thus the metabolism of glycoproteins, demonstrated in Figure 4A PMID:23544079, (IDA), the negative regulation term would be applied to this protein + negative regulation of glycoprotein metabolic process + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of glycoprotein metabolic process. + GOC:BHF + GOC:TermGenie + GOC:rl + GO_REF:0000058 + PMID:23544079 + + + + + down regulation of glycoprotein metabolic process + GOC:TermGenie + + + + + down regulation of glycoprotein metabolism + GOC:TermGenie + + + + + down-regulation of glycoprotein metabolic process + GOC:TermGenie + + + + + down-regulation of glycoprotein metabolism + GOC:TermGenie + + + + + downregulation of glycoprotein metabolic process + GOC:TermGenie + + + + + downregulation of glycoprotein metabolism + GOC:TermGenie + + + + + negative regulation of glycoprotein metabolism + GOC:TermGenie + + + + + inhibition of glycoprotein metabolic process + GOC:TermGenie + + + + + inhibition of glycoprotein metabolism + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of glycoprotein metabolic process. + rl + 2014-05-14T18:44:31Z + positive regulation of glycoprotein metabolism + up regulation of glycoprotein metabolic process + up regulation of glycoprotein metabolism + up-regulation of glycoprotein metabolic process + up-regulation of glycoprotein metabolism + upregulation of glycoprotein metabolic process + upregulation of glycoprotein metabolism + activation of glycoprotein metabolic process + activation of glycoprotein metabolism + biological_process + GO:1903020 + human serum amyloid P component (SAP) P02743 inhibits viral neuraminidase, NA (exo-alpha-sialidase activity) and thus the metabolism of glycoproteins, demonstrated in Figure 4A PMID:23544079, (IDA), the negative regulation term would be applied to this protein + positive regulation of glycoprotein metabolic process + + + + + Any process that activates or increases the frequency, rate or extent of glycoprotein metabolic process. + GOC:BHF + GOC:TermGenie + GOC:rl + GO_REF:0000058 + PMID:23544079 + + + + + positive regulation of glycoprotein metabolism + GOC:TermGenie + + + + + up regulation of glycoprotein metabolic process + GOC:TermGenie + + + + + up regulation of glycoprotein metabolism + GOC:TermGenie + + + + + up-regulation of glycoprotein metabolic process + GOC:TermGenie + + + + + up-regulation of glycoprotein metabolism + GOC:TermGenie + + + + + upregulation of glycoprotein metabolic process + GOC:TermGenie + + + + + upregulation of glycoprotein metabolism + GOC:TermGenie + + + + + activation of glycoprotein metabolic process + GOC:TermGenie + + + + + activation of glycoprotein metabolism + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of response to wounding. + kmv + 2014-05-18T01:28:46Z + regulation of physiological response to wounding + biological_process + GO:1903034 + regulation of response to wounding + + + + + Any process that modulates the frequency, rate or extent of response to wounding. + GOC:TermGenie + GOC:kmv + GO_REF:0000058 + pmid:19164535 + + + + + regulation of physiological response to wounding + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of response to wounding. + kmv + 2014-05-18T01:28:52Z + down regulation of physiological response to wounding + down regulation of response to wounding + down-regulation of physiological response to wounding + down-regulation of response to wounding + downregulation of physiological response to wounding + downregulation of response to wounding + negative regulation of physiological response to wounding + inhibition of physiological response to wounding + inhibition of response to wounding + biological_process + GO:1903035 + negative regulation of response to wounding + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of response to wounding. + GOC:TermGenie + GOC:kmv + GO_REF:0000058 + pmid:19164535 + + + + + down regulation of physiological response to wounding + GOC:TermGenie + + + + + down regulation of response to wounding + GOC:TermGenie + + + + + down-regulation of physiological response to wounding + GOC:TermGenie + + + + + down-regulation of response to wounding + GOC:TermGenie + + + + + downregulation of physiological response to wounding + GOC:TermGenie + + + + + downregulation of response to wounding + GOC:TermGenie + + + + + negative regulation of physiological response to wounding + GOC:TermGenie + + + + + inhibition of physiological response to wounding + GOC:TermGenie + + + + + inhibition of response to wounding + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of response to wounding. + kmv + 2014-05-18T01:28:58Z + positive regulation of physiological response to wounding + up regulation of physiological response to wounding + up regulation of response to wounding + up-regulation of physiological response to wounding + up-regulation of response to wounding + upregulation of physiological response to wounding + upregulation of response to wounding + activation of physiological response to wounding + activation of response to wounding + biological_process + GO:1903036 + positive regulation of response to wounding + + + + + Any process that activates or increases the frequency, rate or extent of response to wounding. + GOC:TermGenie + GOC:kmv + GO_REF:0000058 + pmid:19164535 + + + + + positive regulation of physiological response to wounding + GOC:TermGenie + + + + + up regulation of physiological response to wounding + GOC:TermGenie + + + + + up regulation of response to wounding + GOC:TermGenie + + + + + up-regulation of physiological response to wounding + GOC:TermGenie + + + + + up-regulation of response to wounding + GOC:TermGenie + + + + + upregulation of physiological response to wounding + GOC:TermGenie + + + + + upregulation of response to wounding + GOC:TermGenie + + + + + activation of physiological response to wounding + GOC:TermGenie + + + + + activation of response to wounding + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of leukocyte cell-cell adhesion. + rl + 2014-05-19T15:29:58Z + regulation of leukocyte adhesion + regulation of leukocyte cell adhesion + biological_process + GO:1903037 + Exogenous expression of ASS1 or NOS3 in HUVECs enhances NO production and inhibits monocyte adhesion + regulation of leukocyte cell-cell adhesion + + + + + Any process that modulates the frequency, rate or extent of leukocyte cell-cell adhesion. + GOC:BHF + GOC:TermGenie + GOC:rl + GO_REF:0000058 + PMID:21106532 + + + + + regulation of leukocyte adhesion + GOC:TermGenie + + + + + regulation of leukocyte cell adhesion + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte cell-cell adhesion. + rl + 2014-05-19T15:30:05Z + down regulation of leukocyte adhesion + down regulation of leukocyte cell adhesion + down regulation of leukocyte cell-cell adhesion + down-regulation of leukocyte adhesion + down-regulation of leukocyte cell adhesion + down-regulation of leukocyte cell-cell adhesion + downregulation of leukocyte adhesion + downregulation of leukocyte cell adhesion + downregulation of leukocyte cell-cell adhesion + negative regulation of leukocyte adhesion + negative regulation of leukocyte cell adhesion + inhibition of leukocyte adhesion + inhibition of leukocyte cell adhesion + inhibition of leukocyte cell-cell adhesion + biological_process + GO:1903038 + Exogenous expression of ASS1 or NOS3 in HUVECs enhances NO production and inhibits monocyte adhesion + negative regulation of leukocyte cell-cell adhesion + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte cell-cell adhesion. + GOC:BHF + GOC:TermGenie + GOC:rl + GO_REF:0000058 + PMID:21106532 + + + + + down regulation of leukocyte adhesion + GOC:TermGenie + + + + + down regulation of leukocyte cell adhesion + GOC:TermGenie + + + + + down regulation of leukocyte cell-cell adhesion + GOC:TermGenie + + + + + down-regulation of leukocyte adhesion + GOC:TermGenie + + + + + down-regulation of leukocyte cell adhesion + GOC:TermGenie + + + + + down-regulation of leukocyte cell-cell adhesion + GOC:TermGenie + + + + + downregulation of leukocyte adhesion + GOC:TermGenie + + + + + downregulation of leukocyte cell adhesion + GOC:TermGenie + + + + + downregulation of leukocyte cell-cell adhesion + GOC:TermGenie + + + + + negative regulation of leukocyte adhesion + GOC:TermGenie + + + + + negative regulation of leukocyte cell adhesion + GOC:TermGenie + + + + + inhibition of leukocyte adhesion + GOC:TermGenie + + + + + inhibition of leukocyte cell adhesion + GOC:TermGenie + + + + + inhibition of leukocyte cell-cell adhesion + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of leukocyte cell-cell adhesion. + rl + 2014-05-19T15:30:15Z + positive regulation of leukocyte adhesion + positive regulation of leukocyte cell adhesion + up regulation of leukocyte adhesion + up regulation of leukocyte cell adhesion + up regulation of leukocyte cell-cell adhesion + up-regulation of leukocyte adhesion + up-regulation of leukocyte cell adhesion + up-regulation of leukocyte cell-cell adhesion + upregulation of leukocyte adhesion + upregulation of leukocyte cell adhesion + upregulation of leukocyte cell-cell adhesion + activation of leukocyte adhesion + activation of leukocyte cell adhesion + activation of leukocyte cell-cell adhesion + biological_process + GO:1903039 + Exogenous expression of ASS1 or NOS3 in HUVECs enhances NO production and inhibits monocyte adhesion + positive regulation of leukocyte cell-cell adhesion + + + + + Any process that activates or increases the frequency, rate or extent of leukocyte cell-cell adhesion. + GOC:BHF + GOC:TermGenie + GOC:rl + GO_REF:0000058 + PMID:21106532 + + + + + positive regulation of leukocyte adhesion + GOC:TermGenie + + + + + positive regulation of leukocyte cell adhesion + GOC:TermGenie + + + + + up regulation of leukocyte adhesion + GOC:TermGenie + + + + + up regulation of leukocyte cell adhesion + GOC:TermGenie + + + + + up regulation of leukocyte cell-cell adhesion + GOC:TermGenie + + + + + up-regulation of leukocyte adhesion + GOC:TermGenie + + + + + up-regulation of leukocyte cell adhesion + GOC:TermGenie + + + + + up-regulation of leukocyte cell-cell adhesion + GOC:TermGenie + + + + + upregulation of leukocyte adhesion + GOC:TermGenie + + + + + upregulation of leukocyte cell adhesion + GOC:TermGenie + + + + + upregulation of leukocyte cell-cell adhesion + GOC:TermGenie + + + + + activation of leukocyte adhesion + GOC:TermGenie + + + + + activation of leukocyte cell adhesion + GOC:TermGenie + + + + + activation of leukocyte cell-cell adhesion + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of chondrocyte hypertrophy. + mr + 2014-05-20T21:23:13Z + biological_process + GO:1903041 + regulation of chondrocyte hypertrophy + + + + + Any process that modulates the frequency, rate or extent of chondrocyte hypertrophy. + GOC:TermGenie + GOC:mr + GO_REF:0000058 + PMID:23928032 + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of chondrocyte hypertrophy. + mr + 2014-05-20T21:23:19Z + down regulation of chondrocyte hypertrophy + down-regulation of chondrocyte hypertrophy + downregulation of chondrocyte hypertrophy + inhibition of chondrocyte hypertrophy + biological_process + GO:1903042 + negative regulation of chondrocyte hypertrophy + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of chondrocyte hypertrophy. + GOC:TermGenie + GOC:mr + GO_REF:0000058 + PMID:23928032 + + + + + down regulation of chondrocyte hypertrophy + GOC:TermGenie + + + + + down-regulation of chondrocyte hypertrophy + GOC:TermGenie + + + + + downregulation of chondrocyte hypertrophy + GOC:TermGenie + + + + + inhibition of chondrocyte hypertrophy + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of chondrocyte hypertrophy. + mr + 2014-05-20T21:23:25Z + up regulation of chondrocyte hypertrophy + up-regulation of chondrocyte hypertrophy + upregulation of chondrocyte hypertrophy + activation of chondrocyte hypertrophy + biological_process + GO:1903043 + positive regulation of chondrocyte hypertrophy + + + + + Any process that activates or increases the frequency, rate or extent of chondrocyte hypertrophy. + GOC:TermGenie + GOC:mr + GO_REF:0000058 + PMID:23928032 + + + + + up regulation of chondrocyte hypertrophy + GOC:TermGenie + + + + + up-regulation of chondrocyte hypertrophy + GOC:TermGenie + + + + + upregulation of chondrocyte hypertrophy + GOC:TermGenie + + + + + activation of chondrocyte hypertrophy + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any neural crest cell migration that is involved in sympathetic nervous system development. + rl + 2014-05-22T07:06:02Z + biological_process + GO:1903045 + Sema3a (O08665, mouse) is involved in neural crest cell migration involved in sympathetic nervous system development + neural crest cell migration involved in sympathetic nervous system development + + + + + Any neural crest cell migration that is involved in sympathetic nervous system development. + GOC:BHF + GOC:TermGenie + GOC:rl + GO_REF:0000060 + PMID:19325129 + + + + + + + + + + + + + + + + + + + + + + + + + + + A process that is part of the meiotic cell cycle. + jl + 2014-05-22T14:22:28Z + biological_process + GO:1903046 + + + meiotic cell cycle process + + + + + A process that is part of the meiotic cell cycle. + GOC:TermGenie + GOC:mtg_cell_cycle + GO_REF:0000060 + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of extracellular matrix organization. + rl + 2014-05-23T17:15:41Z + regulation of extracellular matrix organisation + biological_process + regulation of extracellular matrix organization and biogenesis + GO:1903053 + regulation of extracellular matrix organization + + + + + Any process that modulates the frequency, rate or extent of extracellular matrix organization. + GOC:BHF + GOC:TermGenie + GOC:rl + GO_REF:0000058 + PMID:22357537 + + + + + regulation of extracellular matrix organisation + GOC:TermGenie + + + + + regulation of extracellular matrix organization and biogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix organization. + rl + 2014-05-23T17:15:47Z + down regulation of extracellular matrix organisation + down regulation of extracellular matrix organization + down-regulation of extracellular matrix organisation + down-regulation of extracellular matrix organization + downregulation of extracellular matrix organisation + downregulation of extracellular matrix organization + negative regulation of extracellular matrix organisation + inhibition of extracellular matrix organisation + inhibition of extracellular matrix organization + biological_process + down regulation of extracellular matrix organization and biogenesis + down-regulation of extracellular matrix organization and biogenesis + downregulation of extracellular matrix organization and biogenesis + inhibition of extracellular matrix organization and biogenesis + negative regulation of extracellular matrix organization and biogenesis + GO:1903054 + negative regulation of extracellular matrix organization + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix organization. + GOC:BHF + GOC:TermGenie + GOC:rl + GO_REF:0000058 + PMID:22357537 + + + + + down regulation of extracellular matrix organisation + GOC:TermGenie + + + + + down regulation of extracellular matrix organization + GOC:TermGenie + + + + + down-regulation of extracellular matrix organisation + GOC:TermGenie + + + + + down-regulation of extracellular matrix organization + GOC:TermGenie + + + + + downregulation of extracellular matrix organisation + GOC:TermGenie + + + + + downregulation of extracellular matrix organization + GOC:TermGenie + + + + + negative regulation of extracellular matrix organisation + GOC:TermGenie + + + + + inhibition of extracellular matrix organisation + GOC:TermGenie + + + + + inhibition of extracellular matrix organization + GOC:TermGenie + + + + + down regulation of extracellular matrix organization and biogenesis + GOC:TermGenie + + + + + down-regulation of extracellular matrix organization and biogenesis + GOC:TermGenie + + + + + downregulation of extracellular matrix organization and biogenesis + GOC:TermGenie + + + + + inhibition of extracellular matrix organization and biogenesis + GOC:TermGenie + + + + + negative regulation of extracellular matrix organization and biogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of extracellular matrix organization. + rl + 2014-05-23T17:15:53Z + positive regulation of extracellular matrix organisation + up regulation of extracellular matrix organisation + up regulation of extracellular matrix organization + up-regulation of extracellular matrix organisation + up-regulation of extracellular matrix organization + upregulation of extracellular matrix organisation + upregulation of extracellular matrix organization + activation of extracellular matrix organisation + activation of extracellular matrix organization + biological_process + activation of extracellular matrix organization and biogenesis + positive regulation of extracellular matrix organization and biogenesis + up regulation of extracellular matrix organization and biogenesis + up-regulation of extracellular matrix organization and biogenesis + upregulation of extracellular matrix organization and biogenesis + GO:1903055 + positive regulation of extracellular matrix organization + + + + + Any process that activates or increases the frequency, rate or extent of extracellular matrix organization. + GOC:BHF + GOC:TermGenie + GOC:rl + GO_REF:0000058 + PMID:22357537 + + + + + positive regulation of extracellular matrix organisation + GOC:TermGenie + + + + + up regulation of extracellular matrix organisation + GOC:TermGenie + + + + + up regulation of extracellular matrix organization + GOC:TermGenie + + + + + up-regulation of extracellular matrix organisation + GOC:TermGenie + + + + + up-regulation of extracellular matrix organization + GOC:TermGenie + + + + + upregulation of extracellular matrix organisation + GOC:TermGenie + + + + + upregulation of extracellular matrix organization + GOC:TermGenie + + + + + activation of extracellular matrix organisation + GOC:TermGenie + + + + + activation of extracellular matrix organization + GOC:TermGenie + + + + + activation of extracellular matrix organization and biogenesis + GOC:TermGenie + + + + + positive regulation of extracellular matrix organization and biogenesis + GOC:TermGenie + + + + + up regulation of extracellular matrix organization and biogenesis + GOC:TermGenie + + + + + up-regulation of extracellular matrix organization and biogenesis + GOC:TermGenie + + + + + upregulation of extracellular matrix organization and biogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of protein localization to plasma membrane. + tb + 2009-07-10T10:32:44Z + GO:0090003 + GO:1905963 + regulation of protein localization in plasma membrane + biological_process + regulation of establishment of protein localisation in plasma membrane + regulation of establishment of protein localization in plasma membrane + regulation of establishment of protein localization to plasma membrane + regulation of protein localisation in plasma membrane + regulation of protein targeting to plasma membrane + regulation of protein-plasma membrane targeting + GO:1903076 + regulation of protein localization to plasma membrane + + + + + Any process that modulates the frequency, rate or extent of protein localization to plasma membrane. + GOC:BHF + GOC:TermGenie + GOC:rl + GO_REF:0000058 + PMID:11602640 + + + + + regulation of protein localization in plasma membrane + GOC:TermGenie + + + + + regulation of establishment of protein localisation in plasma membrane + GOC:mah + + + + + regulation of protein localisation in plasma membrane + GOC:TermGenie + + + + + regulation of protein-plasma membrane targeting + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to plasma membrane. + tb + 2014-05-29T17:10:16Z + GO:0090005 + GO:1905964 + down regulation of protein localisation in plasma membrane + down regulation of protein localization in plasma membrane + down regulation of protein localization to plasma membrane + down-regulation of protein localisation in plasma membrane + down-regulation of protein localization in plasma membrane + down-regulation of protein localization to plasma membrane + downregulation of protein localisation in plasma membrane + downregulation of protein localization in plasma membrane + downregulation of protein localization to plasma membrane + negative regulation of protein localization in plasma membrane + inhibition of protein localisation in plasma membrane + inhibition of protein localization in plasma membrane + inhibition of protein localization to plasma membrane + inhibition of protein targeting to plasma membrane + inhibition of protein-plasma membrane targeting + biological_process + down regulation of protein targeting to plasma membrane + down regulation of protein-plasma membrane targeting + down-regulation of protein targeting to plasma membrane + down-regulation of protein-plasma membrane targeting + downregulation of protein targeting to plasma membrane + downregulation of protein-plasma membrane targeting + negative regulation of establishment of protein localisation in plasma membrane + negative regulation of establishment of protein localization in plasma membrane + negative regulation of establishment of protein localization to plasma membrane + negative regulation of protein localisation in plasma membrane + negative regulation of protein targeting to plasma membrane + negative regulation of protein-plasma membrane targeting + GO:1903077 + negative regulation of protein localization to plasma membrane + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to plasma membrane. + GOC:BHF + GOC:TermGenie + GOC:rl + GO_REF:0000058 + PMID:11602640 + + + + + down regulation of protein localisation in plasma membrane + GOC:TermGenie + + + + + down regulation of protein localization in plasma membrane + GOC:TermGenie + + + + + down regulation of protein localization to plasma membrane + GOC:TermGenie + + + + + down-regulation of protein localisation in plasma membrane + GOC:TermGenie + + + + + down-regulation of protein localization in plasma membrane + GOC:TermGenie + + + + + down-regulation of protein localization to plasma membrane + GOC:TermGenie + + + + + downregulation of protein localisation in plasma membrane + GOC:TermGenie + + + + + downregulation of protein localization in plasma membrane + GOC:TermGenie + + + + + downregulation of protein localization to plasma membrane + GOC:TermGenie + + + + + negative regulation of protein localization in plasma membrane + GOC:TermGenie + + + + + inhibition of protein localisation in plasma membrane + GOC:TermGenie + + + + + inhibition of protein localization in plasma membrane + GOC:TermGenie + + + + + inhibition of protein localization to plasma membrane + GOC:TermGenie + + + + + inhibition of protein targeting to plasma membrane + GOC:TermGenie + + + + + inhibition of protein-plasma membrane targeting + GOC:TermGenie + + + + + down regulation of protein targeting to plasma membrane + GOC:TermGenie + + + + + down regulation of protein-plasma membrane targeting + GOC:TermGenie + + + + + down-regulation of protein targeting to plasma membrane + GOC:TermGenie + + + + + down-regulation of protein-plasma membrane targeting + GOC:TermGenie + + + + + downregulation of protein targeting to plasma membrane + GOC:TermGenie + + + + + downregulation of protein-plasma membrane targeting + GOC:TermGenie + + + + + negative regulation of establishment of protein localisation in plasma membrane + GOC:mah + + + + + negative regulation of protein localisation in plasma membrane + GOC:TermGenie + + + + + negative regulation of protein-plasma membrane targeting + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of protein localization to plasma membrane. + tb + 2009-07-10T10:34:17Z + GO:0090004 + GO:1905965 + positive regulation of protein localisation in plasma membrane + positive regulation of protein localization in plasma membrane + up regulation of protein localisation in plasma membrane + up regulation of protein localization in plasma membrane + up regulation of protein localization to plasma membrane + up-regulation of protein localisation in plasma membrane + up-regulation of protein localization in plasma membrane + up-regulation of protein localization to plasma membrane + upregulation of protein localisation in plasma membrane + upregulation of protein localization in plasma membrane + upregulation of protein localization to plasma membrane + activation of protein localisation in plasma membrane + activation of protein localization in plasma membrane + activation of protein localization to plasma membrane + activation of protein targeting to plasma membrane + activation of protein-plasma membrane targeting + biological_process + positive regulation of establishment of protein localisation in plasma membrane + positive regulation of establishment of protein localization to plasma membrane + positive regulation of protein targeting to plasma membrane + positive regulation of protein-plasma membrane targeting + up regulation of protein targeting to plasma membrane + up regulation of protein-plasma membrane targeting + up-regulation of protein targeting to plasma membrane + up-regulation of protein-plasma membrane targeting + upregulation of protein targeting to plasma membrane + upregulation of protein-plasma membrane targeting + GO:1903078 + positive regulation of protein localization to plasma membrane + + + + + Any process that activates or increases the frequency, rate or extent of protein localization to plasma membrane. + GOC:BHF + GOC:TermGenie + GOC:rl + GO_REF:0000058 + PMID:11602640 + + + + + positive regulation of protein localisation in plasma membrane + GOC:TermGenie + + + + + positive regulation of protein localization in plasma membrane + GOC:TermGenie + + + + + up regulation of protein localisation in plasma membrane + GOC:TermGenie + + + + + up regulation of protein localization in plasma membrane + GOC:TermGenie + + + + + up regulation of protein localization to plasma membrane + GOC:TermGenie + + + + + up-regulation of protein localisation in plasma membrane + GOC:TermGenie + + + + + up-regulation of protein localization in plasma membrane + GOC:TermGenie + + + + + up-regulation of protein localization to plasma membrane + GOC:TermGenie + + + + + upregulation of protein localisation in plasma membrane + GOC:TermGenie + + + + + upregulation of protein localization in plasma membrane + GOC:TermGenie + + + + + upregulation of protein localization to plasma membrane + GOC:TermGenie + + + + + activation of protein localisation in plasma membrane + GOC:TermGenie + + + + + activation of protein localization in plasma membrane + GOC:TermGenie + + + + + activation of protein localization to plasma membrane + GOC:TermGenie + + + + + activation of protein targeting to plasma membrane + GOC:TermGenie + + + + + activation of protein-plasma membrane targeting + GOC:TermGenie + + + + + positive regulation of establishment of protein localisation in plasma membrane + GOC:mah + + + + + positive regulation of protein-plasma membrane targeting + GOC:TermGenie + + + + + up regulation of protein targeting to plasma membrane + GOC:TermGenie + + + + + up regulation of protein-plasma membrane targeting + GOC:TermGenie + + + + + up-regulation of protein targeting to plasma membrane + GOC:TermGenie + + + + + up-regulation of protein-plasma membrane targeting + GOC:TermGenie + + + + + upregulation of protein targeting to plasma membrane + GOC:TermGenie + + + + + upregulation of protein-plasma membrane targeting + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of actin filament-based movement. + al + 2014-06-12T16:55:57Z + biological_process + GO:1903115 + regulation of actin filament-based movement + + + + + Any process that modulates the frequency, rate or extent of actin filament-based movement. + GOC:TermGenie + GO_REF:0000058 + PMID:24798735 + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of actin filament-based movement. + al + 2014-06-12T16:56:04Z + up regulation of actin filament-based movement + up-regulation of actin filament-based movement + upregulation of actin filament-based movement + activation of actin filament-based movement + biological_process + GO:1903116 + positive regulation of actin filament-based movement + + + + + Any process that activates or increases the frequency, rate or extent of actin filament-based movement. + GOC:TermGenie + GO_REF:0000058 + PMID:24798735 + + + + + up regulation of actin filament-based movement + GOC:TermGenie + + + + + up-regulation of actin filament-based movement + GOC:TermGenie + + + + + upregulation of actin filament-based movement + GOC:TermGenie + + + + + activation of actin filament-based movement + GOC:TermGenie + + + + + + + + + + + + + + + + + + + A process in which a protein is transported to, or maintained in, the location of an actin cytoskeleton. + mah + 2014-06-16T11:27:09Z + protein localisation in actin cytoskeleton + protein localisation to actin cytoskeleton + protein localization in actin cytoskeleton + biological_process + GO:1903119 + protein localization to actin cytoskeleton + + + + + A process in which a protein is transported to, or maintained in, the location of an actin cytoskeleton. + GOC:TermGenie + GO_REF:0000087 + PMID:24798735 + + + + + protein localisation in actin cytoskeleton + GOC:TermGenie + + + + + protein localisation to actin cytoskeleton + GOC:TermGenie + + + + + protein localization in actin cytoskeleton + GOC:TermGenie + + + + + + + + + + + + + + + + + + + A process in which a protein is transported to, or maintained in, the location of an actin filament bundle. + mah + 2014-06-16T11:27:16Z + protein localisation in actin filament bundle + protein localisation to actin filament bundle + protein localization in actin filament bundle + biological_process + protein localization to actin cable + GO:1903120 + protein localization to actin filament bundle + + + + + A process in which a protein is transported to, or maintained in, the location of an actin filament bundle. + GOC:TermGenie + GO_REF:0000087 + PMID:24798735 + + + + + protein localisation in actin filament bundle + GOC:TermGenie + + + + + protein localisation to actin filament bundle + GOC:TermGenie + + + + + protein localization in actin filament bundle + GOC:TermGenie + + + + + protein localization to actin cable + GOC:mah + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires the specialized features of a mononuclear cell. + cls + 2014-06-25T15:47:09Z + biological_process + GO:1903131 + mononuclear cell differentiation + + + + + The process in which a relatively unspecialized cell acquires the specialized features of a mononuclear cell. + CL:0000842 + GOC:TermGenie + GO_REF:0000086 + PMID:24759906 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of tube lumen cavitation. + dph + 2014-06-25T20:18:58Z + biological_process + GO:1903132 + regulation of tube lumen cavitation + + + + + Any process that modulates the frequency, rate or extent of tube lumen cavitation. + GOC:TermGenie + GOC:dph + GO_REF:0000058 + PMID:22898778 + + + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of tube lumen cavitation. + dph + 2014-06-25T20:19:04Z + inhibition of tube lumen cavitation + biological_process + GO:1903133 + negative regulation of tube lumen cavitation + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of tube lumen cavitation. + GOC:TermGenie + GOC:dph + GO_REF:0000058 + PMID:22898778 + + + + + inhibition of tube lumen cavitation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process involved in the maintenance of an internal steady state of carbon dioxide within an organism or cell. + mr + 2014-07-11T20:58:24Z + biological_process + GO:1903171 + carbon dioxide homeostasis + + + + + Any process involved in the maintenance of an internal steady state of carbon dioxide within an organism or cell. + GOC:TermGenie + GOC:mr + GO_REF:0000072 + PMID:16571594 + + + + + + + + + + + + + + + + + + + Any biological process involved in the maintenance of an internal steady state of carbon dioxide at the level of the cell. + mr + 2014-07-11T20:58:30Z + biological_process + GO:1903172 + cellular carbon dioxide homeostasis + + + + + Any biological process involved in the maintenance of an internal steady state of carbon dioxide at the level of the cell. + GOC:TermGenie + GOC:mr + GO_REF:0000072 + PMID:16571594 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of dopamine biosynthetic process. + bf + 2014-07-14T12:17:41Z + regulation of dopamine anabolism + regulation of dopamine biosynthesis + regulation of dopamine formation + regulation of dopamine synthesis + biological_process + GO:1903179 + regulation of dopamine biosynthetic process + + + + + Any process that modulates the frequency, rate or extent of dopamine biosynthetic process. + GOC:PARL + GOC:TermGenie + GOC:bf + GO_REF:0000058 + + + + + regulation of dopamine anabolism + GOC:TermGenie + + + + + regulation of dopamine biosynthesis + GOC:TermGenie + + + + + regulation of dopamine formation + GOC:TermGenie + + + + + regulation of dopamine synthesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of dopamine biosynthetic process. + bf + 2014-07-14T12:17:47Z + down regulation of dopamine anabolism + down regulation of dopamine biosynthesis + down regulation of dopamine biosynthetic process + down regulation of dopamine formation + down regulation of dopamine synthesis + down-regulation of dopamine anabolism + down-regulation of dopamine biosynthesis + down-regulation of dopamine biosynthetic process + down-regulation of dopamine formation + down-regulation of dopamine synthesis + downregulation of dopamine anabolism + downregulation of dopamine biosynthesis + downregulation of dopamine biosynthetic process + downregulation of dopamine formation + downregulation of dopamine synthesis + negative regulation of dopamine anabolism + negative regulation of dopamine biosynthesis + negative regulation of dopamine formation + negative regulation of dopamine synthesis + inhibition of dopamine anabolism + inhibition of dopamine biosynthesis + inhibition of dopamine biosynthetic process + inhibition of dopamine formation + inhibition of dopamine synthesis + biological_process + GO:1903180 + negative regulation of dopamine biosynthetic process + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of dopamine biosynthetic process. + GOC:PARL + GOC:TermGenie + GOC:bf + GO_REF:0000058 + + + + + down regulation of dopamine anabolism + GOC:TermGenie + + + + + down regulation of dopamine biosynthesis + GOC:TermGenie + + + + + down regulation of dopamine biosynthetic process + GOC:TermGenie + + + + + down regulation of dopamine formation + GOC:TermGenie + + + + + down regulation of dopamine synthesis + GOC:TermGenie + + + + + down-regulation of dopamine anabolism + GOC:TermGenie + + + + + down-regulation of dopamine biosynthesis + GOC:TermGenie + + + + + down-regulation of dopamine biosynthetic process + GOC:TermGenie + + + + + down-regulation of dopamine formation + GOC:TermGenie + + + + + down-regulation of dopamine synthesis + GOC:TermGenie + + + + + downregulation of dopamine anabolism + GOC:TermGenie + + + + + downregulation of dopamine biosynthesis + GOC:TermGenie + + + + + downregulation of dopamine biosynthetic process + GOC:TermGenie + + + + + downregulation of dopamine formation + GOC:TermGenie + + + + + downregulation of dopamine synthesis + GOC:TermGenie + + + + + negative regulation of dopamine anabolism + GOC:TermGenie + + + + + negative regulation of dopamine biosynthesis + GOC:TermGenie + + + + + negative regulation of dopamine formation + GOC:TermGenie + + + + + negative regulation of dopamine synthesis + GOC:TermGenie + + + + + inhibition of dopamine anabolism + GOC:TermGenie + + + + + inhibition of dopamine biosynthesis + GOC:TermGenie + + + + + inhibition of dopamine biosynthetic process + GOC:TermGenie + + + + + inhibition of dopamine formation + GOC:TermGenie + + + + + inhibition of dopamine synthesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of dopamine biosynthetic process. + bf + 2014-07-14T12:17:53Z + positive regulation of dopamine anabolism + positive regulation of dopamine biosynthesis + positive regulation of dopamine formation + positive regulation of dopamine synthesis + up regulation of dopamine anabolism + up regulation of dopamine biosynthesis + up regulation of dopamine biosynthetic process + up regulation of dopamine formation + up regulation of dopamine synthesis + up-regulation of dopamine anabolism + up-regulation of dopamine biosynthesis + up-regulation of dopamine biosynthetic process + up-regulation of dopamine formation + up-regulation of dopamine synthesis + upregulation of dopamine anabolism + upregulation of dopamine biosynthesis + upregulation of dopamine biosynthetic process + upregulation of dopamine formation + upregulation of dopamine synthesis + activation of dopamine anabolism + activation of dopamine biosynthesis + activation of dopamine biosynthetic process + activation of dopamine formation + activation of dopamine synthesis + biological_process + GO:1903181 + positive regulation of dopamine biosynthetic process + + + + + Any process that activates or increases the frequency, rate or extent of dopamine biosynthetic process. + GOC:PARL + GOC:TermGenie + GOC:bf + GO_REF:0000058 + PMID:19703902 + + + + + positive regulation of dopamine anabolism + GOC:TermGenie + + + + + positive regulation of dopamine biosynthesis + GOC:TermGenie + + + + + positive regulation of dopamine formation + GOC:TermGenie + + + + + positive regulation of dopamine synthesis + GOC:TermGenie + + + + + up regulation of dopamine anabolism + GOC:TermGenie + + + + + up regulation of dopamine biosynthesis + GOC:TermGenie + + + + + up regulation of dopamine biosynthetic process + GOC:TermGenie + + + + + up regulation of dopamine formation + GOC:TermGenie + + + + + up regulation of dopamine synthesis + GOC:TermGenie + + + + + up-regulation of dopamine anabolism + GOC:TermGenie + + + + + up-regulation of dopamine biosynthesis + GOC:TermGenie + + + + + up-regulation of dopamine biosynthetic process + GOC:TermGenie + + + + + up-regulation of dopamine formation + GOC:TermGenie + + + + + up-regulation of dopamine synthesis + GOC:TermGenie + + + + + upregulation of dopamine anabolism + GOC:TermGenie + + + + + upregulation of dopamine biosynthesis + GOC:TermGenie + + + + + upregulation of dopamine biosynthetic process + GOC:TermGenie + + + + + upregulation of dopamine formation + GOC:TermGenie + + + + + upregulation of dopamine synthesis + GOC:TermGenie + + + + + activation of dopamine anabolism + GOC:TermGenie + + + + + activation of dopamine biosynthesis + GOC:TermGenie + + + + + activation of dopamine biosynthetic process + GOC:TermGenie + + + + + activation of dopamine formation + GOC:TermGenie + + + + + activation of dopamine synthesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of endodermal cell differentiation. + als + 2014-07-29T13:22:35Z + regulation of endoderm cell differentiation + biological_process + GO:1903224 + regulation of endodermal cell differentiation + + + + + Any process that modulates the frequency, rate or extent of endodermal cell differentiation. + GOC:TermGenie + GOC:als + GO_REF:0000058 + PMID:23154389 + + + + + regulation of endoderm cell differentiation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of endodermal cell differentiation. + als + 2014-07-29T13:22:41Z + down regulation of endoderm cell differentiation + down regulation of endodermal cell differentiation + down-regulation of endoderm cell differentiation + down-regulation of endodermal cell differentiation + downregulation of endoderm cell differentiation + downregulation of endodermal cell differentiation + negative regulation of endoderm cell differentiation + inhibition of endoderm cell differentiation + inhibition of endodermal cell differentiation + biological_process + GO:1903225 + negative regulation of endodermal cell differentiation + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of endodermal cell differentiation. + GOC:TermGenie + GOC:als + GO_REF:0000058 + PMID:23154389 + + + + + down regulation of endoderm cell differentiation + GOC:TermGenie + + + + + down regulation of endodermal cell differentiation + GOC:TermGenie + + + + + down-regulation of endoderm cell differentiation + GOC:TermGenie + + + + + down-regulation of endodermal cell differentiation + GOC:TermGenie + + + + + downregulation of endoderm cell differentiation + GOC:TermGenie + + + + + downregulation of endodermal cell differentiation + GOC:TermGenie + + + + + negative regulation of endoderm cell differentiation + GOC:TermGenie + + + + + inhibition of endoderm cell differentiation + GOC:TermGenie + + + + + inhibition of endodermal cell differentiation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of endodermal cell differentiation. + als + 2014-07-29T13:22:47Z + positive regulation of endoderm cell differentiation + up regulation of endoderm cell differentiation + up regulation of endodermal cell differentiation + up-regulation of endoderm cell differentiation + up-regulation of endodermal cell differentiation + upregulation of endoderm cell differentiation + upregulation of endodermal cell differentiation + activation of endoderm cell differentiation + activation of endodermal cell differentiation + biological_process + GO:1903226 + positive regulation of endodermal cell differentiation + + + + + Any process that activates or increases the frequency, rate or extent of endodermal cell differentiation. + GOC:TermGenie + GOC:als + GO_REF:0000058 + PMID:23154389 + + + + + positive regulation of endoderm cell differentiation + GOC:TermGenie + + + + + up regulation of endoderm cell differentiation + GOC:TermGenie + + + + + up regulation of endodermal cell differentiation + GOC:TermGenie + + + + + up-regulation of endoderm cell differentiation + GOC:TermGenie + + + + + up-regulation of endodermal cell differentiation + GOC:TermGenie + + + + + upregulation of endoderm cell differentiation + GOC:TermGenie + + + + + upregulation of endodermal cell differentiation + GOC:TermGenie + + + + + activation of endoderm cell differentiation + GOC:TermGenie + + + + + activation of endodermal cell differentiation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + A process in which a protein is transported to, or maintained in, a location within a Golgi membrane. + mah + 2014-08-12T14:22:31Z + protein localisation in Golgi membrane + protein localisation to Golgi membrane + protein localization in Golgi membrane + biological_process + GO:1903292 + protein localization to Golgi membrane + + + + + A process in which a protein is transported to, or maintained in, a location within a Golgi membrane. + GOC:TermGenie + GO_REF:0000087 + PMID:11378902 + + + + + protein localisation in Golgi membrane + GOC:TermGenie + + + + + protein localisation to Golgi membrane + GOC:TermGenie + + + + + protein localization in Golgi membrane + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of regulated secretory pathway. + pad + 2014-08-18T10:04:53Z + biological_process + GO:1903305 + An example of this is protein domain-specific expression of Synaptotagmin 1 in rat (P21707) in PMID:12526776 inferred from mutant phenotype. + regulation of regulated secretory pathway + + + + + Any process that modulates the frequency, rate or extent of regulated secretory pathway. + GOC:PARL + GOC:TermGenie + GOC:pad + GO_REF:0000058 + PMID:12526776 + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of regulated secretory pathway. + pad + 2014-08-18T10:05:02Z + down regulation of regulated secretory pathway + down-regulation of regulated secretory pathway + downregulation of regulated secretory pathway + inhibition of regulated secretory pathway + biological_process + GO:1903306 + An example of this is protein domain-specific expression of Synaptotagmin 1 in rat (P21707) in PMID:12526776 inferred from mutant phenotype. + negative regulation of regulated secretory pathway + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of regulated secretory pathway. + GOC:PARL + GOC:TermGenie + GOC:pad + GO_REF:0000058 + PMID:12526776 + + + + + down regulation of regulated secretory pathway + GOC:TermGenie + + + + + down-regulation of regulated secretory pathway + GOC:TermGenie + + + + + downregulation of regulated secretory pathway + GOC:TermGenie + + + + + inhibition of regulated secretory pathway + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of regulated secretory pathway. + pad + 2014-08-18T10:05:10Z + up regulation of regulated secretory pathway + up-regulation of regulated secretory pathway + upregulation of regulated secretory pathway + activation of regulated secretory pathway + biological_process + GO:1903307 + An example of this is protein domain-specific expression of Synaptotagmin 1 in rat (P21707) in PMID:12526776 inferred from mutant phenotype. + positive regulation of regulated secretory pathway + + + + + Any process that activates or increases the frequency, rate or extent of regulated secretory pathway. + GOC:PARL + GOC:TermGenie + GOC:pad + GO_REF:0000058 + PMID:12526776 + + + + + up regulation of regulated secretory pathway + GOC:TermGenie + + + + + up-regulation of regulated secretory pathway + GOC:TermGenie + + + + + upregulation of regulated secretory pathway + GOC:TermGenie + + + + + activation of regulated secretory pathway + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of vacuolar transport. + vw + 2014-08-18T13:16:04Z + biological_process + GO:1903335 + regulation of vacuolar transport + + + + + Any process that modulates the frequency, rate or extent of vacuolar transport. + GOC:TermGenie + GOC:vw + GO_REF:0000058 + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of vacuolar transport. + vw + 2014-08-18T13:16:11Z + down regulation of vacuolar transport + down-regulation of vacuolar transport + downregulation of vacuolar transport + inhibition of vacuolar transport + biological_process + GO:1903336 + negative regulation of vacuolar transport + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of vacuolar transport. + GOC:TermGenie + GOC:vw + GO_REF:0000058 + + + + + down regulation of vacuolar transport + GOC:TermGenie + + + + + down-regulation of vacuolar transport + GOC:TermGenie + + + + + downregulation of vacuolar transport + GOC:TermGenie + + + + + inhibition of vacuolar transport + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of vacuolar transport. + vw + 2014-08-18T13:16:19Z + up regulation of vacuolar transport + up-regulation of vacuolar transport + upregulation of vacuolar transport + activation of vacuolar transport + biological_process + GO:1903337 + positive regulation of vacuolar transport + + + + + Any process that activates or increases the frequency, rate or extent of vacuolar transport. + GOC:TermGenie + GOC:vw + GO_REF:0000058 + + + + + up regulation of vacuolar transport + GOC:TermGenie + + + + + up-regulation of vacuolar transport + GOC:TermGenie + + + + + upregulation of vacuolar transport + GOC:TermGenie + + + + + activation of vacuolar transport + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of tight junction assembly. + pr + 2014-08-19T11:02:14Z + down regulation of tight junction assembly + down regulation of tight junction formation + down-regulation of tight junction assembly + down-regulation of tight junction formation + downregulation of tight junction assembly + downregulation of tight junction formation + negative regulation of tight junction formation + inhibition of tight junction assembly + inhibition of tight junction formation + biological_process + GO:1903347 + negative regulation of bicellular tight junction assembly + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of tight junction assembly. + GOC:TermGenie + GOC:jz + GO_REF:0000058 + PMID:25050009 + + + + + down regulation of tight junction assembly + GOC:TermGenie + + + + + down regulation of tight junction formation + GOC:TermGenie + + + + + down-regulation of tight junction assembly + GOC:TermGenie + + + + + down-regulation of tight junction formation + GOC:TermGenie + + + + + downregulation of tight junction assembly + GOC:TermGenie + + + + + downregulation of tight junction formation + GOC:TermGenie + + + + + negative regulation of tight junction formation + GOC:TermGenie + + + + + inhibition of tight junction assembly + GOC:TermGenie + + + + + inhibition of tight junction formation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of tight junction assembly. + pr + 2014-08-19T11:05:06Z + positive regulation of tight junction formation + up regulation of tight junction assembly + up regulation of tight junction formation + up-regulation of tight junction assembly + up-regulation of tight junction formation + upregulation of tight junction assembly + upregulation of tight junction formation + activation of tight junction assembly + activation of tight junction formation + biological_process + GO:1903348 + positive regulation of bicellular tight junction assembly + + + + + Any process that activates or increases the frequency, rate or extent of tight junction assembly. + GOC:TermGenie + GOC:jz + GO_REF:0000058 + PMID:25050009 + + + + + positive regulation of tight junction formation + GOC:TermGenie + + + + + up regulation of tight junction assembly + GOC:TermGenie + + + + + up regulation of tight junction formation + GOC:TermGenie + + + + + up-regulation of tight junction assembly + GOC:TermGenie + + + + + up-regulation of tight junction formation + GOC:TermGenie + + + + + upregulation of tight junction assembly + GOC:TermGenie + + + + + upregulation of tight junction formation + GOC:TermGenie + + + + + activation of tight junction assembly + GOC:TermGenie + + + + + activation of tight junction formation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dopamine stimulus. + mr + 2014-08-19T19:33:26Z + biological_process + GO:1903350 + response to dopamine + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dopamine stimulus. + GOC:TermGenie + GOC:mr + GO_REF:0000071 + PMID:11118945 + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dopamine stimulus. + mr + 2014-08-19T19:33:35Z + biological_process + GO:1903351 + cellular response to dopamine + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dopamine stimulus. + GOC:TermGenie + GOC:mr + GO_REF:0000071 + PMID:11118945 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of nucleus organization. + hjd + 2014-08-20T19:36:16Z + regulation of nuclear organisation + regulation of nuclear organization + biological_process + regulation of nuclear morphology + regulation of nuclear organization and biogenesis + regulation of nucleus organization and biogenesis + GO:1903353 + regulation of nucleus organization + + + + + Any process that modulates the frequency, rate or extent of nucleus organization. + GOC:TermGenie + GO_REF:0000058 + PMID:16943282 + + + + + regulation of nuclear organisation + GOC:TermGenie + + + + + regulation of nuclear organization + GOC:TermGenie + + + + + regulation of nuclear morphology + GOC:TermGenie + + + + + regulation of nuclear organization and biogenesis + GOC:TermGenie + + + + + regulation of nucleus organization and biogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of Golgi organization. + als + 2014-08-21T10:22:22Z + regulation of Golgi organisation + biological_process + regulation of Golgi organization and biogenesis + GO:1903358 + regulation of Golgi organization + + + + + Any process that modulates the frequency, rate or extent of Golgi organization. + GOC:TermGenie + GOC:als + GO_REF:0000058 + PMID:17562788 + + + + + regulation of Golgi organisation + GOC:TermGenie + + + + + regulation of Golgi organization and biogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of an acoustico-facial VII-VIII ganglion complex over time, from its formation to the mature structure. + bf + 2014-08-26T12:40:36Z + acoustico-facial VII-VIII ganglion complex development + acousticofacial ganglion development + facio-acoustic VII-VIII ganglion complex development + facio-acoustic ganglion complex VII-VIII development + facio-acoustic ganglion development + biological_process + GO:1903375 + facioacoustic ganglion development + + + + + The process whose specific outcome is the progression of an acoustico-facial VII-VIII ganglion complex over time, from its formation to the mature structure. + GOC:PARL + GOC:TermGenie + GOC:bf + GOC:mat + GO_REF:0000094 + PMID:18356247 + + + + + acoustico-facial VII-VIII ganglion complex development + UBERON:0012175 + + + + + acousticofacial ganglion development + GOC:TermGenie + + + + + facio-acoustic VII-VIII ganglion complex development + GOC:TermGenie + + + + + facio-acoustic ganglion complex VII-VIII development + GOC:TermGenie + + + + + facio-acoustic ganglion development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus. + rl + 2014-09-03T12:45:43Z + biological_process + GO:1903412 + response to bile acid + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus. + GOC:BHF + GOC:TermGenie + GOC:rl + GO_REF:0000071 + PMID:21757002 + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus. + rl + 2014-09-03T12:45:51Z + biological_process + GO:1903413 + cellular response to bile acid + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus. + GOC:BHF + GOC:TermGenie + GOC:rl + GO_REF:0000071 + PMID:21757002 + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of cell maturation. + jl + 2014-09-15T13:31:23Z + biological_process + regulation of functional differentiation + GO:1903429 + regulation of cell maturation + + + + + Any process that modulates the frequency, rate or extent of cell maturation. + GOC:TermGenie + GO_REF:0000058 + PMID:17459944 + + + + + regulation of functional differentiation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cell maturation. + jl + 2014-09-15T13:31:32Z + down regulation of cell maturation + down-regulation of cell maturation + downregulation of cell maturation + inhibition of cell maturation + biological_process + down regulation of functional differentiation + down-regulation of functional differentiation + downregulation of functional differentiation + inhibition of functional differentiation + negative regulation of functional differentiation + GO:1903430 + negative regulation of cell maturation + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cell maturation. + GOC:TermGenie + GO_REF:0000058 + PMID:17459944 + + + + + down regulation of cell maturation + GOC:TermGenie + + + + + down-regulation of cell maturation + GOC:TermGenie + + + + + downregulation of cell maturation + GOC:TermGenie + + + + + inhibition of cell maturation + GOC:TermGenie + + + + + down regulation of functional differentiation + GOC:TermGenie + + + + + down-regulation of functional differentiation + GOC:TermGenie + + + + + downregulation of functional differentiation + GOC:TermGenie + + + + + inhibition of functional differentiation + GOC:TermGenie + + + + + negative regulation of functional differentiation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of cell maturation. + jl + 2014-09-15T13:31:41Z + up regulation of cell maturation + up-regulation of cell maturation + upregulation of cell maturation + activation of cell maturation + biological_process + activation of functional differentiation + positive regulation of functional differentiation + up regulation of functional differentiation + up-regulation of functional differentiation + upregulation of functional differentiation + GO:1903431 + positive regulation of cell maturation + + + + + Any process that activates or increases the frequency, rate or extent of cell maturation. + GOC:TermGenie + GO_REF:0000058 + PMID:17459944 + + + + + up regulation of cell maturation + GOC:TermGenie + + + + + up-regulation of cell maturation + GOC:TermGenie + + + + + upregulation of cell maturation + GOC:TermGenie + + + + + activation of cell maturation + GOC:TermGenie + + + + + activation of functional differentiation + GOC:TermGenie + + + + + positive regulation of functional differentiation + GOC:TermGenie + + + + + up regulation of functional differentiation + GOC:TermGenie + + + + + up-regulation of functional differentiation + GOC:TermGenie + + + + + upregulation of functional differentiation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + + A protein complex which is capable of calcitonin family receptor activity. Calcitonin family receptors may form dimers, trimers or tetramers; adrenomedullin and amylin receptors have only been observed as dimers so far. + pr + 2014-09-16T13:25:11Z + cellular_component + GO:1903439 + calcitonin family receptor complex + + + + + A protein complex which is capable of calcitonin family receptor activity. Calcitonin family receptors may form dimers, trimers or tetramers; adrenomedullin and amylin receptors have only been observed as dimers so far. + GOC:TermGenie + GOC:bhm + GO_REF:0000088 + PMID:10871296 + PMID:12037140 + PMID:18687416 + + + + + + + + + + + + + + + + + + + A process in which a protein is transported to, or maintained in, a location within a ciliary membrane. + pr + 2014-09-16T15:15:39Z + protein localisation in ciliary membrane + protein localisation to ciliary membrane + protein localization in ciliary membrane + biological_process + GO:1903441 + protein localization to ciliary membrane + + + + + A process in which a protein is transported to, or maintained in, a location within a ciliary membrane. + GOC:TermGenie + GOC:cilia + GOC:krc + GO_REF:0000087 + PMID:22139371 + + + + + protein localisation in ciliary membrane + GOC:TermGenie + + + + + protein localisation to ciliary membrane + GOC:TermGenie + + + + + protein localization in ciliary membrane + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of brown fat cell differentiation. + hjd + 2014-09-17T19:15:00Z + down regulation of brown adipocyte cell differentiation + down regulation of brown adipocyte differentiation + down regulation of brown fat cell differentiation + down-regulation of brown adipocyte cell differentiation + down-regulation of brown adipocyte differentiation + down-regulation of brown fat cell differentiation + downregulation of brown adipocyte cell differentiation + downregulation of brown adipocyte differentiation + downregulation of brown fat cell differentiation + negative regulation of brown adipocyte cell differentiation + negative regulation of brown adipocyte differentiation + inhibition of brown adipocyte cell differentiation + inhibition of brown adipocyte differentiation + inhibition of brown fat cell differentiation + biological_process + GO:1903444 + negative regulation of brown fat cell differentiation + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of brown fat cell differentiation. + GOC:TermGenie + GO_REF:0000058 + PMID:23977283 + + + + + down regulation of brown adipocyte cell differentiation + GOC:TermGenie + + + + + down regulation of brown adipocyte differentiation + GOC:TermGenie + + + + + down regulation of brown fat cell differentiation + GOC:TermGenie + + + + + down-regulation of brown adipocyte cell differentiation + GOC:TermGenie + + + + + down-regulation of brown adipocyte differentiation + GOC:TermGenie + + + + + down-regulation of brown fat cell differentiation + GOC:TermGenie + + + + + downregulation of brown adipocyte cell differentiation + GOC:TermGenie + + + + + downregulation of brown adipocyte differentiation + GOC:TermGenie + + + + + downregulation of brown fat cell differentiation + GOC:TermGenie + + + + + negative regulation of brown adipocyte cell differentiation + GOC:TermGenie + + + + + negative regulation of brown adipocyte differentiation + GOC:TermGenie + + + + + inhibition of brown adipocyte cell differentiation + GOC:TermGenie + + + + + inhibition of brown adipocyte differentiation + GOC:TermGenie + + + + + inhibition of brown fat cell differentiation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of lactation. + mr + 2014-09-24T14:44:13Z + biological_process + GO:1903487 + regulation of lactation + + + + + Any process that modulates the frequency, rate or extent of lactation. + GOC:TermGenie + GOC:mr + GO_REF:0000058 + PMID:19563620 + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of lactation. + mr + 2014-09-24T14:44:22Z + down regulation of lactation + down-regulation of lactation + downregulation of lactation + inhibition of lactation + biological_process + GO:1903488 + negative regulation of lactation + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of lactation. + GOC:TermGenie + GOC:mr + GO_REF:0000058 + PMID:19563620 + + + + + down regulation of lactation + GOC:TermGenie + + + + + down-regulation of lactation + GOC:TermGenie + + + + + downregulation of lactation + GOC:TermGenie + + + + + inhibition of lactation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of lactation. + mr + 2014-09-24T14:44:30Z + up regulation of lactation + up-regulation of lactation + upregulation of lactation + activation of lactation + biological_process + GO:1903489 + positive regulation of lactation + + + + + Any process that activates or increases the frequency, rate or extent of lactation. + GOC:TermGenie + GOC:mr + GO_REF:0000058 + PMID:19563620 + + + + + up regulation of lactation + GOC:TermGenie + + + + + up-regulation of lactation + GOC:TermGenie + + + + + upregulation of lactation + GOC:TermGenie + + + + + activation of lactation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + The chemical reactions and pathways involving mucopolysaccharide. + dph + 2014-10-01T21:55:47Z + mucopolysaccharide metabolism + biological_process + GO:1903510 + mucopolysaccharide metabolic process + + + + + The chemical reactions and pathways involving mucopolysaccharide. + GOC:TermGenie + GOC:dph + GO_REF:0000068 + PMID:4236091 + + + + + mucopolysaccharide metabolism + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of blood circulation. + mr + 2014-10-06T18:38:56Z + biological_process + regulation of hemolymph circulation + GO:1903522 + regulation of blood circulation + + + + + Any process that modulates the frequency, rate or extent of blood circulation. + GOC:TermGenie + GOC:mr + GO_REF:0000058 + PMID:10659969 + + + + + regulation of hemolymph circulation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of blood circulation. + mr + 2014-10-06T18:39:05Z + down regulation of blood circulation + down-regulation of blood circulation + downregulation of blood circulation + inhibition of blood circulation + biological_process + down regulation of hemolymph circulation + down-regulation of hemolymph circulation + downregulation of hemolymph circulation + inhibition of hemolymph circulation + negative regulation of hemolymph circulation + GO:1903523 + negative regulation of blood circulation + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of blood circulation. + GOC:TermGenie + GOC:mr + GO_REF:0000058 + PMID:10659969 + + + + + down regulation of blood circulation + GOC:TermGenie + + + + + down-regulation of blood circulation + GOC:TermGenie + + + + + downregulation of blood circulation + GOC:TermGenie + + + + + inhibition of blood circulation + GOC:TermGenie + + + + + down regulation of hemolymph circulation + GOC:TermGenie + + + + + down-regulation of hemolymph circulation + GOC:TermGenie + + + + + downregulation of hemolymph circulation + GOC:TermGenie + + + + + inhibition of hemolymph circulation + GOC:TermGenie + + + + + negative regulation of hemolymph circulation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of blood circulation. + mr + 2014-10-06T18:39:13Z + up regulation of blood circulation + up-regulation of blood circulation + upregulation of blood circulation + activation of blood circulation + biological_process + activation of hemolymph circulation + positive regulation of hemolymph circulation + up regulation of hemolymph circulation + up-regulation of hemolymph circulation + upregulation of hemolymph circulation + GO:1903524 + positive regulation of blood circulation + + + + + Any process that activates or increases the frequency, rate or extent of blood circulation. + GOC:TermGenie + GOC:mr + GO_REF:0000058 + PMID:10659969 + + + + + up regulation of blood circulation + GOC:TermGenie + + + + + up-regulation of blood circulation + GOC:TermGenie + + + + + upregulation of blood circulation + GOC:TermGenie + + + + + activation of blood circulation + GOC:TermGenie + + + + + activation of hemolymph circulation + GOC:TermGenie + + + + + positive regulation of hemolymph circulation + GOC:TermGenie + + + + + up regulation of hemolymph circulation + GOC:TermGenie + + + + + up-regulation of hemolymph circulation + GOC:TermGenie + + + + + upregulation of hemolymph circulation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of secretion by cell. + pm + 2014-10-08T13:24:59Z + regulation of cellular secretion + biological_process + GO:1903530 + regulation of secretion by cell + + + + + Any process that modulates the frequency, rate or extent of secretion by cell. + GOC:TermGenie + GOC:pm + GO_REF:0000058 + PMID:12130530 + + + + + regulation of cellular secretion + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of secretion by cell. + pm + 2014-10-08T13:25:08Z + down regulation of cellular secretion + down regulation of secretion by cell + down-regulation of cellular secretion + down-regulation of secretion by cell + downregulation of cellular secretion + downregulation of secretion by cell + negative regulation of cellular secretion + inhibition of cellular secretion + inhibition of secretion by cell + biological_process + GO:1903531 + negative regulation of secretion by cell + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of secretion by cell. + GOC:TermGenie + GOC:pm + GO_REF:0000058 + PMID:12130530 + + + + + down regulation of cellular secretion + GOC:TermGenie + + + + + down regulation of secretion by cell + GOC:TermGenie + + + + + down-regulation of cellular secretion + GOC:TermGenie + + + + + down-regulation of secretion by cell + GOC:TermGenie + + + + + downregulation of cellular secretion + GOC:TermGenie + + + + + downregulation of secretion by cell + GOC:TermGenie + + + + + negative regulation of cellular secretion + GOC:TermGenie + + + + + inhibition of cellular secretion + GOC:TermGenie + + + + + inhibition of secretion by cell + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of secretion by cell. + pm + 2014-10-08T13:25:17Z + positive regulation of cellular secretion + up regulation of cellular secretion + up regulation of secretion by cell + up-regulation of cellular secretion + up-regulation of secretion by cell + upregulation of cellular secretion + upregulation of secretion by cell + activation of cellular secretion + activation of secretion by cell + biological_process + GO:1903532 + positive regulation of secretion by cell + + + + + Any process that activates or increases the frequency, rate or extent of secretion by cell. + GOC:TermGenie + GOC:pm + GO_REF:0000058 + PMID:12130530 + + + + + positive regulation of cellular secretion + GOC:TermGenie + + + + + up regulation of cellular secretion + GOC:TermGenie + + + + + up regulation of secretion by cell + GOC:TermGenie + + + + + up-regulation of cellular secretion + GOC:TermGenie + + + + + up-regulation of secretion by cell + GOC:TermGenie + + + + + upregulation of cellular secretion + GOC:TermGenie + + + + + upregulation of secretion by cell + GOC:TermGenie + + + + + activation of cellular secretion + GOC:TermGenie + + + + + activation of secretion by cell + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any meiotic cell cycle process that is involved in oocyte maturation. + pr + 2014-10-09T10:46:14Z + meiosis involved in oocyte maturation + biological_process + GO:1903537 + meiotic cell cycle process involved in oocyte maturation + + + + + Any meiotic cell cycle process that is involved in oocyte maturation. + GOC:TermGenie + GOC:jz + GO_REF:0000060 + PMID:25212395 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation. + pr + 2014-10-09T10:52:38Z + regulation of meiosis involved in oocyte maturation + biological_process + GO:1903538 + regulation of meiotic cell cycle process involved in oocyte maturation + + + + + Any process that modulates the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation. + GOC:TermGenie + GOC:jz + GO_REF:0000058 + PMID:25212395 + + + + + regulation of meiosis involved in oocyte maturation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + A process in which a protein is transported to, or maintained in, a location within a photoreceptor outer segment. + krc + 2014-10-17T21:14:11Z + protein localisation in photoreceptor outer segment + protein localisation to photoreceptor outer segment + protein localization in photoreceptor outer segment + biological_process + GO:1903546 + protein localization to photoreceptor outer segment + + + + + A process in which a protein is transported to, or maintained in, a location within a photoreceptor outer segment. + GOC:TermGenie + GO_REF:0000087 + PMID:11481257 + PMID:21867699 + + + + + protein localisation in photoreceptor outer segment + GOC:TermGenie + + + + + protein localisation to photoreceptor outer segment + GOC:TermGenie + + + + + protein localization in photoreceptor outer segment + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + Any vesicle that is part of the extracellular region. + jl + 2014-10-22T14:26:11Z + cellular_component + microparticle + GO:1903561 + extracellular vesicle + + + + + Any vesicle that is part of the extracellular region. + GOC:TermGenie + GOC:pm + GO_REF:0000064 + PMID:24769233 + + + + + microparticle + GOC:vesicles + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of protein localization to cilium. + krc + 2014-10-24T20:58:11Z + biological_process + GO:1903564 + regulation of protein localization to cilium + + + + + Any process that modulates the frequency, rate or extent of protein localization to cilium. + GOC:TermGenie + GOC:cilia + GOC:krc + GO_REF:0000058 + PMID:22072986 + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cilium. + krc + 2014-10-24T20:58:20Z + down regulation of protein localization to cilium + down-regulation of protein localization to cilium + downregulation of protein localization to cilium + inhibition of protein localization to cilium + biological_process + GO:1903565 + negative regulation of protein localization to cilium + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cilium. + GOC:TermGenie + GOC:cilia + GOC:krc + GO_REF:0000058 + PMID:22072986 + + + + + down regulation of protein localization to cilium + GOC:TermGenie + + + + + down-regulation of protein localization to cilium + GOC:TermGenie + + + + + downregulation of protein localization to cilium + GOC:TermGenie + + + + + inhibition of protein localization to cilium + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of protein localization to cilium. + krc + 2014-10-24T20:58:28Z + up regulation of protein localization to cilium + up-regulation of protein localization to cilium + upregulation of protein localization to cilium + activation of protein localization to cilium + biological_process + GO:1903566 + positive regulation of protein localization to cilium + + + + + Any process that activates or increases the frequency, rate or extent of protein localization to cilium. + GOC:TermGenie + GOC:cilia + GOC:krc + GO_REF:0000058 + PMID:22072986 + + + + + up regulation of protein localization to cilium + GOC:TermGenie + + + + + up-regulation of protein localization to cilium + GOC:TermGenie + + + + + upregulation of protein localization to cilium + GOC:TermGenie + + + + + activation of protein localization to cilium + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of protein localization to ciliary membrane. + krc + 2014-10-24T21:32:51Z + regulation of protein localisation in ciliary membrane + regulation of protein localisation to ciliary membrane + regulation of protein localization in ciliary membrane + biological_process + GO:1903567 + regulation of protein localization to ciliary membrane + + + + + Any process that modulates the frequency, rate or extent of protein localization to ciliary membrane. + GOC:TermGenie + GOC:cilia + GOC:krc + GO_REF:0000058 + PMID:22072986 + + + + + regulation of protein localisation in ciliary membrane + GOC:TermGenie + + + + + regulation of protein localisation to ciliary membrane + GOC:TermGenie + + + + + regulation of protein localization in ciliary membrane + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to ciliary membrane. + krc + 2014-10-24T21:32:59Z + down regulation of protein localisation in ciliary membrane + down regulation of protein localisation to ciliary membrane + down regulation of protein localization in ciliary membrane + down regulation of protein localization to ciliary membrane + down-regulation of protein localisation in ciliary membrane + down-regulation of protein localisation to ciliary membrane + down-regulation of protein localization in ciliary membrane + down-regulation of protein localization to ciliary membrane + downregulation of protein localisation in ciliary membrane + downregulation of protein localisation to ciliary membrane + downregulation of protein localization in ciliary membrane + downregulation of protein localization to ciliary membrane + negative regulation of protein localisation in ciliary membrane + negative regulation of protein localisation to ciliary membrane + negative regulation of protein localization in ciliary membrane + inhibition of protein localisation in ciliary membrane + inhibition of protein localisation to ciliary membrane + inhibition of protein localization in ciliary membrane + inhibition of protein localization to ciliary membrane + biological_process + GO:1903568 + negative regulation of protein localization to ciliary membrane + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to ciliary membrane. + GOC:TermGenie + GOC:cilia + GOC:krc + GO_REF:0000058 + PMID:22072986 + + + + + down regulation of protein localisation in ciliary membrane + GOC:TermGenie + + + + + down regulation of protein localisation to ciliary membrane + GOC:TermGenie + + + + + down regulation of protein localization in ciliary membrane + GOC:TermGenie + + + + + down regulation of protein localization to ciliary membrane + GOC:TermGenie + + + + + down-regulation of protein localisation in ciliary membrane + GOC:TermGenie + + + + + down-regulation of protein localisation to ciliary membrane + GOC:TermGenie + + + + + down-regulation of protein localization in ciliary membrane + GOC:TermGenie + + + + + down-regulation of protein localization to ciliary membrane + GOC:TermGenie + + + + + downregulation of protein localisation in ciliary membrane + GOC:TermGenie + + + + + downregulation of protein localisation to ciliary membrane + GOC:TermGenie + + + + + downregulation of protein localization in ciliary membrane + GOC:TermGenie + + + + + downregulation of protein localization to ciliary membrane + GOC:TermGenie + + + + + negative regulation of protein localisation in ciliary membrane + GOC:TermGenie + + + + + negative regulation of protein localisation to ciliary membrane + GOC:TermGenie + + + + + negative regulation of protein localization in ciliary membrane + GOC:TermGenie + + + + + inhibition of protein localisation in ciliary membrane + GOC:TermGenie + + + + + inhibition of protein localisation to ciliary membrane + GOC:TermGenie + + + + + inhibition of protein localization in ciliary membrane + GOC:TermGenie + + + + + inhibition of protein localization to ciliary membrane + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of protein localization to ciliary membrane. + krc + 2014-10-24T21:33:08Z + positive regulation of protein localisation in ciliary membrane + positive regulation of protein localisation to ciliary membrane + positive regulation of protein localization in ciliary membrane + up regulation of protein localisation in ciliary membrane + up regulation of protein localisation to ciliary membrane + up regulation of protein localization in ciliary membrane + up regulation of protein localization to ciliary membrane + up-regulation of protein localisation in ciliary membrane + up-regulation of protein localisation to ciliary membrane + up-regulation of protein localization in ciliary membrane + up-regulation of protein localization to ciliary membrane + upregulation of protein localisation in ciliary membrane + upregulation of protein localisation to ciliary membrane + upregulation of protein localization in ciliary membrane + upregulation of protein localization to ciliary membrane + activation of protein localisation in ciliary membrane + activation of protein localisation to ciliary membrane + activation of protein localization in ciliary membrane + activation of protein localization to ciliary membrane + biological_process + GO:1903569 + positive regulation of protein localization to ciliary membrane + + + + + Any process that activates or increases the frequency, rate or extent of protein localization to ciliary membrane. + GOC:TermGenie + GOC:cilia + GOC:krc + GO_REF:0000058 + PMID:22072986 + + + + + positive regulation of protein localisation in ciliary membrane + GOC:TermGenie + + + + + positive regulation of protein localisation to ciliary membrane + GOC:TermGenie + + + + + positive regulation of protein localization in ciliary membrane + GOC:TermGenie + + + + + up regulation of protein localisation in ciliary membrane + GOC:TermGenie + + + + + up regulation of protein localisation to ciliary membrane + GOC:TermGenie + + + + + up regulation of protein localization in ciliary membrane + GOC:TermGenie + + + + + up regulation of protein localization to ciliary membrane + GOC:TermGenie + + + + + up-regulation of protein localisation in ciliary membrane + GOC:TermGenie + + + + + up-regulation of protein localisation to ciliary membrane + GOC:TermGenie + + + + + up-regulation of protein localization in ciliary membrane + GOC:TermGenie + + + + + up-regulation of protein localization to ciliary membrane + GOC:TermGenie + + + + + upregulation of protein localisation in ciliary membrane + GOC:TermGenie + + + + + upregulation of protein localisation to ciliary membrane + GOC:TermGenie + + + + + upregulation of protein localization in ciliary membrane + GOC:TermGenie + + + + + upregulation of protein localization to ciliary membrane + GOC:TermGenie + + + + + activation of protein localisation in ciliary membrane + GOC:TermGenie + + + + + activation of protein localisation to ciliary membrane + GOC:TermGenie + + + + + activation of protein localization in ciliary membrane + GOC:TermGenie + + + + + activation of protein localization to ciliary membrane + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of microvillus assembly. + als + 2014-12-03T11:45:08Z + down regulation of microvillus assembly + down-regulation of microvillus assembly + downregulation of microvillus assembly + inhibition of microvillus assembly + biological_process + down regulation of microvillus biogenesis + down-regulation of microvillus biogenesis + downregulation of microvillus biogenesis + inhibition of microvillus biogenesis + negative regulation of microvillus biogenesis + GO:1903697 + negative regulation of microvillus assembly + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of microvillus assembly. + GOC:TermGenie + GOC:als + GO_REF:0000058 + PMID:22797597 + + + + + down regulation of microvillus assembly + GOC:TermGenie + + + + + down-regulation of microvillus assembly + GOC:TermGenie + + + + + downregulation of microvillus assembly + GOC:TermGenie + + + + + inhibition of microvillus assembly + GOC:TermGenie + + + + + down regulation of microvillus biogenesis + GOC:TermGenie + + + + + down-regulation of microvillus biogenesis + GOC:TermGenie + + + + + downregulation of microvillus biogenesis + GOC:TermGenie + + + + + inhibition of microvillus biogenesis + GOC:TermGenie + + + + + negative regulation of microvillus biogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of microvillus assembly. + als + 2014-12-03T11:45:17Z + up regulation of microvillus assembly + up-regulation of microvillus assembly + upregulation of microvillus assembly + activation of microvillus assembly + biological_process + activation of microvillus biogenesis + positive regulation of microvillus biogenesis + up regulation of microvillus biogenesis + up-regulation of microvillus biogenesis + upregulation of microvillus biogenesis + GO:1903698 + positive regulation of microvillus assembly + + + + + Any process that activates or increases the frequency, rate or extent of microvillus assembly. + GOC:TermGenie + GOC:als + GO_REF:0000058 + PMID:22797597 + + + + + up regulation of microvillus assembly + GOC:TermGenie + + + + + up-regulation of microvillus assembly + GOC:TermGenie + + + + + upregulation of microvillus assembly + GOC:TermGenie + + + + + activation of microvillus assembly + GOC:TermGenie + + + + + activation of microvillus biogenesis + GOC:TermGenie + + + + + positive regulation of microvillus biogenesis + GOC:TermGenie + + + + + up regulation of microvillus biogenesis + GOC:TermGenie + + + + + up-regulation of microvillus biogenesis + GOC:TermGenie + + + + + upregulation of microvillus biogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a tarsal gland over time, from its formation to the mature structure. + cls + 2014-12-03T11:47:07Z + Meibomian gland development + gland of Meibom development + glandula tarsales development + biological_process + tarsoconjunctival gland development + GO:1903699 + tarsal gland development + + + + + The process whose specific outcome is the progression of a tarsal gland over time, from its formation to the mature structure. + GOC:TermGenie + GO_REF:0000094 + PMID:20664693 + + + + + Meibomian gland development + GOC:TermGenie + + + + + gland of Meibom development + GOC:TermGenie + + + + + glandula tarsales development + GOC:TermGenie + + + + + tarsoconjunctival gland development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a caecum over time, from its formation to the mature structure. + cls + 2014-12-03T12:05:00Z + cecum development + intestinum crassum caecum development + caeca development + ceca development + biological_process + blind intestine development + blindgut development + intestinum caecum development + intestinum crassum cecum development + GO:1903700 + caecum development + + + + + The process whose specific outcome is the progression of a caecum over time, from its formation to the mature structure. + GOC:TermGenie + GO_REF:0000094 + ISBN:0-683-40008-8 + + + + + cecum development + GOC:TermGenie + + + + + intestinum crassum caecum development + GOC:TermGenie + + + + + caeca development + GOC:TermGenie + + + + + ceca development + GOC:TermGenie + + + + + blind intestine development + GOC:TermGenie + + + + + blindgut development + GOC:TermGenie + + + + + intestinum caecum development + GOC:TermGenie + + + + + intestinum crassum cecum development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a substantia propria of cornea over time, from its formation to the mature structure. + cls + 2014-12-03T13:12:09Z + corneal stroma development + stroma of cornea development + biological_process + substantia propria development + GO:1903701 + substantia propria of cornea development + + + + + The process whose specific outcome is the progression of a substantia propria of cornea over time, from its formation to the mature structure. + GOC:TermGenie + GO_REF:0000094 + PMID:12556382 + + + + + corneal stroma development + GOC:TermGenie + + + + + stroma of cornea development + GOC:TermGenie + + + + + substantia propria development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of an esophagus over time, from its formation to the mature structure. + cls + 2014-12-03T14:41:30Z + esophageal development + gullet development + oesophagus development + biological_process + GO:1903702 + esophagus development + + + + + The process whose specific outcome is the progression of an esophagus over time, from its formation to the mature structure. + GOC:TermGenie + GO_REF:0000094 + ISBN:0-683-40008-8 + + + + + esophageal development + MGI:csmith + + + + + gullet development + GOC:TermGenie + + + + + oesophagus development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of hemopoiesis. + pad + 2014-12-04T15:34:13Z + regulation of blood cell biosynthesis + regulation of blood cell formation + regulation of haemopoiesis + regulation of hematopoiesis + biological_process + GO:1903706 + An example of this is Atg7 in mouse (UniProt symbol, Q9D906) in PMID:20080761, inferred from mutant phenotype. + regulation of hemopoiesis + + + + + Any process that modulates the frequency, rate or extent of hemopoiesis. + GOC:PARL + GOC:TermGenie + GOC:pad + GO_REF:0000058 + PMID:20080761 + + + + + regulation of blood cell biosynthesis + GOC:TermGenie + + + + + regulation of blood cell formation + GOC:TermGenie + + + + + regulation of haemopoiesis + GOC:TermGenie + + + + + regulation of hematopoiesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of hemopoiesis. + pad + 2014-12-04T15:34:21Z + down regulation of blood cell biosynthesis + down regulation of blood cell formation + down regulation of haemopoiesis + down regulation of hematopoiesis + down regulation of hemopoiesis + down-regulation of blood cell biosynthesis + down-regulation of blood cell formation + down-regulation of haemopoiesis + down-regulation of hematopoiesis + down-regulation of hemopoiesis + downregulation of blood cell biosynthesis + downregulation of blood cell formation + downregulation of haemopoiesis + downregulation of hematopoiesis + downregulation of hemopoiesis + negative regulation of blood cell biosynthesis + negative regulation of blood cell formation + negative regulation of haemopoiesis + negative regulation of hematopoiesis + inhibition of blood cell biosynthesis + inhibition of blood cell formation + inhibition of haemopoiesis + inhibition of hematopoiesis + inhibition of hemopoiesis + biological_process + GO:1903707 + An example of this is Atg7 in mouse (UniProt symbol, Q9D906) in PMID:20080761, inferred from mutant phenotype. + negative regulation of hemopoiesis + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of hemopoiesis. + GOC:PARL + GOC:TermGenie + GOC:pad + GO_REF:0000058 + PMID:20080761 + + + + + down regulation of blood cell biosynthesis + GOC:TermGenie + + + + + down regulation of blood cell formation + GOC:TermGenie + + + + + down regulation of haemopoiesis + GOC:TermGenie + + + + + down regulation of hematopoiesis + GOC:TermGenie + + + + + down regulation of hemopoiesis + GOC:TermGenie + + + + + down-regulation of blood cell biosynthesis + GOC:TermGenie + + + + + down-regulation of blood cell formation + GOC:TermGenie + + + + + down-regulation of haemopoiesis + GOC:TermGenie + + + + + down-regulation of hematopoiesis + GOC:TermGenie + + + + + down-regulation of hemopoiesis + GOC:TermGenie + + + + + downregulation of blood cell biosynthesis + GOC:TermGenie + + + + + downregulation of blood cell formation + GOC:TermGenie + + + + + downregulation of haemopoiesis + GOC:TermGenie + + + + + downregulation of hematopoiesis + GOC:TermGenie + + + + + downregulation of hemopoiesis + GOC:TermGenie + + + + + negative regulation of blood cell biosynthesis + GOC:TermGenie + + + + + negative regulation of blood cell formation + GOC:TermGenie + + + + + negative regulation of haemopoiesis + GOC:TermGenie + + + + + negative regulation of hematopoiesis + GOC:TermGenie + + + + + inhibition of blood cell biosynthesis + GOC:TermGenie + + + + + inhibition of blood cell formation + GOC:TermGenie + + + + + inhibition of haemopoiesis + GOC:TermGenie + + + + + inhibition of hematopoiesis + GOC:TermGenie + + + + + inhibition of hemopoiesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of hemopoiesis. + pad + 2014-12-04T15:34:30Z + positive regulation of blood cell biosynthesis + positive regulation of blood cell formation + positive regulation of haemopoiesis + positive regulation of hematopoiesis + up regulation of blood cell biosynthesis + up regulation of blood cell formation + up regulation of haemopoiesis + up regulation of hematopoiesis + up regulation of hemopoiesis + up-regulation of blood cell biosynthesis + up-regulation of blood cell formation + up-regulation of haemopoiesis + up-regulation of hematopoiesis + up-regulation of hemopoiesis + upregulation of blood cell biosynthesis + upregulation of blood cell formation + upregulation of haemopoiesis + upregulation of hematopoiesis + upregulation of hemopoiesis + activation of blood cell biosynthesis + activation of blood cell formation + activation of haemopoiesis + activation of hematopoiesis + activation of hemopoiesis + biological_process + GO:1903708 + An example of this is Atg7 in mouse (UniProt symbol, Q9D906) in PMID:20080761, inferred from mutant phenotype. + positive regulation of hemopoiesis + + + + + Any process that activates or increases the frequency, rate or extent of hemopoiesis. + GOC:PARL + GOC:TermGenie + GOC:pad + GO_REF:0000058 + PMID:20080761 + + + + + positive regulation of blood cell biosynthesis + GOC:TermGenie + + + + + positive regulation of blood cell formation + GOC:TermGenie + + + + + positive regulation of haemopoiesis + GOC:TermGenie + + + + + positive regulation of hematopoiesis + GOC:TermGenie + + + + + up regulation of blood cell biosynthesis + GOC:TermGenie + + + + + up regulation of blood cell formation + GOC:TermGenie + + + + + up regulation of haemopoiesis + GOC:TermGenie + + + + + up regulation of hematopoiesis + GOC:TermGenie + + + + + up regulation of hemopoiesis + GOC:TermGenie + + + + + up-regulation of blood cell biosynthesis + GOC:TermGenie + + + + + up-regulation of blood cell formation + GOC:TermGenie + + + + + up-regulation of haemopoiesis + GOC:TermGenie + + + + + up-regulation of hematopoiesis + GOC:TermGenie + + + + + up-regulation of hemopoiesis + GOC:TermGenie + + + + + upregulation of blood cell biosynthesis + GOC:TermGenie + + + + + upregulation of blood cell formation + GOC:TermGenie + + + + + upregulation of haemopoiesis + GOC:TermGenie + + + + + upregulation of hematopoiesis + GOC:TermGenie + + + + + upregulation of hemopoiesis + GOC:TermGenie + + + + + activation of blood cell biosynthesis + GOC:TermGenie + + + + + activation of blood cell formation + GOC:TermGenie + + + + + activation of haemopoiesis + GOC:TermGenie + + + + + activation of hematopoiesis + GOC:TermGenie + + + + + activation of hemopoiesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of an uterine gland over time, from its formation to the mature structure. + cls + 2014-12-04T18:57:21Z + endometrial gland development + endometrium gland development + uterine glands development + uterine glands set development + biological_process + glandulae uterinae development + glandular part of endometrium development + set of uterine glands development + GO:1903709 + uterine gland development + + + + + The process whose specific outcome is the progression of an uterine gland over time, from its formation to the mature structure. + GOC:TermGenie + GO_REF:0000094 + PMID:23619340 + + + + + endometrial gland development + GOC:TermGenie + + + + + endometrium gland development + GOC:TermGenie + + + + + uterine glands development + GOC:TermGenie + + + + + uterine glands set development + GOC:TermGenie + + + + + glandulae uterinae development + GOC:TermGenie + + + + + glandular part of endometrium development + GOC:TermGenie + + + + + set of uterine glands development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + The process in which a relatively unspecialized cell acquires the specialized features of a luteal cell. Large luteal cells develop from granulosa cells. Small luteal cells develop from theca cells. + cjm + 2014-12-10T01:36:43Z + lutein cell differentiation + biological_process + GO:1903728 + luteal cell differentiation + + + + + The process in which a relatively unspecialized cell acquires the specialized features of a luteal cell. Large luteal cells develop from granulosa cells. Small luteal cells develop from theca cells. + GOC:TermGenie + GO_REF:0000086 + MP:0001133 + + + + + lutein cell differentiation + CL:0000175 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of plasma membrane organization. + al + 2014-12-10T18:59:44Z + regulation of plasma membrane organisation + biological_process + regulation of plasma membrane organization and biogenesis + GO:1903729 + regulation of plasma membrane organization + + + + + Any process that modulates the frequency, rate or extent of plasma membrane organization. + GOC:TermGenie + GO_REF:0000058 + PMID:24514900 + + + + + regulation of plasma membrane organisation + GOC:TermGenie + + + + + regulation of plasma membrane organization and biogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + A protein complex which is capable of taste receptor activity. + rl + 2014-12-22T16:53:45Z + cellular_component + GO:1903768 + taste receptor complex + + + + + A protein complex which is capable of taste receptor activity. + GOC:BHF + GOC:TermGenie + GOC:rl + GO_REF:0000088 + PMID:16720576 + + + + + + + + + + + + + + + + + + + A process in which a protein is transported to, or maintained in, a location within a vacuolar membrane. + mah + 2015-01-07T13:15:54Z + protein localisation in vacuolar membrane + protein localisation to vacuolar membrane + protein localization in vacuolar membrane + biological_process + GO:1903778 + protein localization to vacuolar membrane + + + + + A process in which a protein is transported to, or maintained in, a location within a vacuolar membrane. + GOC:TermGenie + GO_REF:0000087 + PMID:25378562 + + + + + protein localisation in vacuolar membrane + GOC:TermGenie + + + + + protein localisation to vacuolar membrane + GOC:TermGenie + + + + + protein localization in vacuolar membrane + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of a protein localization. + https://github.com/geneontology/go-ontology/issues/22021 + jl + 2015-01-20T14:32:24Z + down regulation of cellular protein localisation + down regulation of cellular protein localization + down-regulation of cellular protein localisation + down-regulation of cellular protein localization + downregulation of cellular protein localisation + downregulation of cellular protein localization + negative regulation of cellular protein localisation + negative regulation of cellular protein localization + inhibition of cellular protein localisation + inhibition of cellular protein localization + biological_process + GO:1903828 + negative regulation of protein localization + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of a protein localization. + GOC:TermGenie + GOC:vw + GO_REF:0000058 + + + + + down regulation of cellular protein localisation + GOC:TermGenie + + + + + down regulation of cellular protein localization + GOC:TermGenie + + + + + down-regulation of cellular protein localisation + GOC:TermGenie + + + + + down-regulation of cellular protein localization + GOC:TermGenie + + + + + downregulation of cellular protein localisation + GOC:TermGenie + + + + + downregulation of cellular protein localization + GOC:TermGenie + + + + + negative regulation of cellular protein localisation + GOC:TermGenie + + + + + inhibition of cellular protein localisation + GOC:TermGenie + + + + + inhibition of cellular protein localization + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of a protein localization. + https://github.com/geneontology/go-ontology/issues/22021 + jl + 2015-01-20T14:32:33Z + positive regulation of cellular protein localisation + positive regulation of cellular protein localization + up regulation of cellular protein localisation + up regulation of cellular protein localization + up-regulation of cellular protein localisation + up-regulation of cellular protein localization + upregulation of cellular protein localisation + upregulation of cellular protein localization + biological_process + GO:1903829 + positive regulation of protein localization + + + + + Any process that activates or increases the frequency, rate or extent of a protein localization. + GOC:TermGenie + GOC:vw + GO_REF:0000058 + + + + + positive regulation of cellular protein localisation + GOC:TermGenie + + + + + up regulation of cellular protein localisation + GOC:TermGenie + + + + + up regulation of cellular protein localization + GOC:TermGenie + + + + + up-regulation of cellular protein localisation + GOC:TermGenie + + + + + up-regulation of cellular protein localization + GOC:TermGenie + + + + + upregulation of cellular protein localisation + GOC:TermGenie + + + + + upregulation of cellular protein localization + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any signal transduction that is involved in cellular response to ammonium ion. + al + 2015-01-21T17:52:09Z + signaling cascade involved in cellular response to ammonium ion + signalling cascade involved in cellular response to ammonium ion + biological_process + signaling pathway involved in cellular response to ammonium ion + signalling pathway involved in cellular response to ammonium ion + GO:1903831 + signal transduction involved in cellular response to ammonium ion + + + + + Any signal transduction that is involved in cellular response to ammonium ion. + GOC:TermGenie + GO_REF:0000060 + PMID:16297994 + + + + + signaling cascade involved in cellular response to ammonium ion + GOC:TermGenie + + + + + signalling cascade involved in cellular response to ammonium ion + GOC:TermGenie + + + + + signaling pathway involved in cellular response to ammonium ion + GOC:TermGenie + + + + + signalling pathway involved in cellular response to ammonium ion + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of aorta morphogenesis. + rph + 2015-01-23T14:00:51Z + biological_process + GO:1903847 + regulation of aorta morphogenesis + + + + + Any process that modulates the frequency, rate or extent of aorta morphogenesis. + GOC:BHF + GOC:BHF_miRNA + GOC:TermGenie + GOC:rph + GO_REF:0000058 + PMID:22269326 + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of aorta morphogenesis. + rph + 2015-01-23T14:01:01Z + down regulation of aorta morphogenesis + down-regulation of aorta morphogenesis + downregulation of aorta morphogenesis + inhibition of aorta morphogenesis + biological_process + GO:1903848 + negative regulation of aorta morphogenesis + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of aorta morphogenesis. + GOC:BHF + GOC:BHF_miRNA + GOC:TermGenie + GOC:rph + GO_REF:0000058 + PMID:22269326 + + + + + down regulation of aorta morphogenesis + GOC:TermGenie + + + + + down-regulation of aorta morphogenesis + GOC:TermGenie + + + + + downregulation of aorta morphogenesis + GOC:TermGenie + + + + + inhibition of aorta morphogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of aorta morphogenesis. + rph + 2015-01-23T14:01:09Z + up regulation of aorta morphogenesis + up-regulation of aorta morphogenesis + upregulation of aorta morphogenesis + activation of aorta morphogenesis + biological_process + GO:1903849 + positive regulation of aorta morphogenesis + + + + + Any process that activates or increases the frequency, rate or extent of aorta morphogenesis. + GOC:BHF + GOC:BHF_miRNA + GOC:TermGenie + GOC:rph + GO_REF:0000058 + PMID:22269326 + + + + + up regulation of aorta morphogenesis + GOC:TermGenie + + + + + up-regulation of aorta morphogenesis + GOC:TermGenie + + + + + upregulation of aorta morphogenesis + GOC:TermGenie + + + + + activation of aorta morphogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of an extraembryonic membrane over time, from its formation to the mature structure. + cjm + 2015-02-05T00:42:16Z + biological_process + GO:1903867 + extraembryonic membrane development + + + + + The process whose specific outcome is the progression of an extraembryonic membrane over time, from its formation to the mature structure. + GOC:TermGenie + GO_REF:0000094 + ISBN:0073040584 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of establishment of T cell polarity. + als + 2015-02-09T10:50:21Z + regulation of T cell polarization + regulation of T lymphocyte polarization + regulation of T-cell polarization + regulation of establishment of T lymphocyte polarity + regulation of establishment of T-cell polarity + regulation of establishment of T-lymphocyte polarity + biological_process + GO:1903903 + regulation of establishment of T cell polarity + + + + + Any process that modulates the frequency, rate or extent of establishment of T cell polarity. + GOC:TermGenie + GOC:als + GO_REF:0000058 + PMID:23575248 + + + + + regulation of T cell polarization + GOC:TermGenie + + + + + regulation of T lymphocyte polarization + GOC:TermGenie + + + + + regulation of T-cell polarization + GOC:TermGenie + + + + + regulation of establishment of T lymphocyte polarity + GOC:TermGenie + + + + + regulation of establishment of T-cell polarity + GOC:TermGenie + + + + + regulation of establishment of T-lymphocyte polarity + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of establishment of T cell polarity. + als + 2015-02-09T10:50:30Z + down regulation of T cell polarization + down regulation of T lymphocyte polarization + down regulation of T-cell polarization + down regulation of establishment of T cell polarity + down regulation of establishment of T lymphocyte polarity + down regulation of establishment of T-cell polarity + down regulation of establishment of T-lymphocyte polarity + down-regulation of T cell polarization + down-regulation of T lymphocyte polarization + down-regulation of T-cell polarization + down-regulation of establishment of T cell polarity + down-regulation of establishment of T lymphocyte polarity + down-regulation of establishment of T-cell polarity + down-regulation of establishment of T-lymphocyte polarity + downregulation of T cell polarization + downregulation of T lymphocyte polarization + downregulation of T-cell polarization + downregulation of establishment of T cell polarity + downregulation of establishment of T lymphocyte polarity + downregulation of establishment of T-cell polarity + downregulation of establishment of T-lymphocyte polarity + negative regulation of T cell polarization + negative regulation of T lymphocyte polarization + negative regulation of T-cell polarization + negative regulation of establishment of T lymphocyte polarity + negative regulation of establishment of T-cell polarity + negative regulation of establishment of T-lymphocyte polarity + inhibition of T cell polarization + inhibition of T lymphocyte polarization + inhibition of T-cell polarization + inhibition of establishment of T cell polarity + inhibition of establishment of T lymphocyte polarity + inhibition of establishment of T-cell polarity + inhibition of establishment of T-lymphocyte polarity + biological_process + GO:1903904 + negative regulation of establishment of T cell polarity + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of establishment of T cell polarity. + GOC:TermGenie + GOC:als + GO_REF:0000058 + PMID:23575248 + + + + + down regulation of T cell polarization + GOC:TermGenie + + + + + down regulation of T lymphocyte polarization + GOC:TermGenie + + + + + down regulation of T-cell polarization + GOC:TermGenie + + + + + down regulation of establishment of T cell polarity + GOC:TermGenie + + + + + down regulation of establishment of T lymphocyte polarity + GOC:TermGenie + + + + + down regulation of establishment of T-cell polarity + GOC:TermGenie + + + + + down regulation of establishment of T-lymphocyte polarity + GOC:TermGenie + + + + + down-regulation of T cell polarization + GOC:TermGenie + + + + + down-regulation of T lymphocyte polarization + GOC:TermGenie + + + + + down-regulation of T-cell polarization + GOC:TermGenie + + + + + down-regulation of establishment of T cell polarity + GOC:TermGenie + + + + + down-regulation of establishment of T lymphocyte polarity + GOC:TermGenie + + + + + down-regulation of establishment of T-cell polarity + GOC:TermGenie + + + + + down-regulation of establishment of T-lymphocyte polarity + GOC:TermGenie + + + + + downregulation of T cell polarization + GOC:TermGenie + + + + + downregulation of T lymphocyte polarization + GOC:TermGenie + + + + + downregulation of T-cell polarization + GOC:TermGenie + + + + + downregulation of establishment of T cell polarity + GOC:TermGenie + + + + + downregulation of establishment of T lymphocyte polarity + GOC:TermGenie + + + + + downregulation of establishment of T-cell polarity + GOC:TermGenie + + + + + downregulation of establishment of T-lymphocyte polarity + GOC:TermGenie + + + + + negative regulation of T cell polarization + GOC:TermGenie + + + + + negative regulation of T lymphocyte polarization + GOC:TermGenie + + + + + negative regulation of T-cell polarization + GOC:TermGenie + + + + + negative regulation of establishment of T lymphocyte polarity + GOC:TermGenie + + + + + negative regulation of establishment of T-cell polarity + GOC:TermGenie + + + + + negative regulation of establishment of T-lymphocyte polarity + GOC:TermGenie + + + + + inhibition of T cell polarization + GOC:TermGenie + + + + + inhibition of T lymphocyte polarization + GOC:TermGenie + + + + + inhibition of T-cell polarization + GOC:TermGenie + + + + + inhibition of establishment of T cell polarity + GOC:TermGenie + + + + + inhibition of establishment of T lymphocyte polarity + GOC:TermGenie + + + + + inhibition of establishment of T-cell polarity + GOC:TermGenie + + + + + inhibition of establishment of T-lymphocyte polarity + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of establishment of T cell polarity. + als + 2015-02-09T10:50:40Z + positive regulation of T cell polarization + positive regulation of T lymphocyte polarization + positive regulation of T-cell polarization + positive regulation of establishment of T lymphocyte polarity + positive regulation of establishment of T-cell polarity + positive regulation of establishment of T-lymphocyte polarity + up regulation of T cell polarization + up regulation of T lymphocyte polarization + up regulation of T-cell polarization + up regulation of establishment of T cell polarity + up regulation of establishment of T lymphocyte polarity + up regulation of establishment of T-cell polarity + up regulation of establishment of T-lymphocyte polarity + up-regulation of T cell polarization + up-regulation of T lymphocyte polarization + up-regulation of T-cell polarization + up-regulation of establishment of T cell polarity + up-regulation of establishment of T lymphocyte polarity + up-regulation of establishment of T-cell polarity + up-regulation of establishment of T-lymphocyte polarity + upregulation of T cell polarization + upregulation of T lymphocyte polarization + upregulation of T-cell polarization + upregulation of establishment of T cell polarity + upregulation of establishment of T lymphocyte polarity + upregulation of establishment of T-cell polarity + upregulation of establishment of T-lymphocyte polarity + activation of T cell polarization + activation of T lymphocyte polarization + activation of T-cell polarization + activation of establishment of T cell polarity + activation of establishment of T lymphocyte polarity + activation of establishment of T-cell polarity + activation of establishment of T-lymphocyte polarity + biological_process + GO:1903905 + positive regulation of establishment of T cell polarity + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that activates or increases the frequency, rate or extent of establishment of T cell polarity. + GOC:TermGenie + GOC:als + GO_REF:0000058 + PMID:23575248 + + + + + positive regulation of T cell polarization + GOC:TermGenie + + + + + positive regulation of T lymphocyte polarization + GOC:TermGenie + + + + + positive regulation of T-cell polarization + GOC:TermGenie + + + + + positive regulation of establishment of T lymphocyte polarity + GOC:TermGenie + + + + + positive regulation of establishment of T-cell polarity + GOC:TermGenie + + + + + positive regulation of establishment of T-lymphocyte polarity + GOC:TermGenie + + + + + up regulation of T cell polarization + GOC:TermGenie + + + + + up regulation of T lymphocyte polarization + GOC:TermGenie + + + + + up regulation of T-cell polarization + GOC:TermGenie + + + + + up regulation of establishment of T cell polarity + GOC:TermGenie + + + + + up regulation of establishment of T lymphocyte polarity + GOC:TermGenie + + + + + up regulation of establishment of T-cell polarity + GOC:TermGenie + + + + + up regulation of establishment of T-lymphocyte polarity + GOC:TermGenie + + + + + up-regulation of T cell polarization + GOC:TermGenie + + + + + up-regulation of T lymphocyte polarization + GOC:TermGenie + + + + + up-regulation of T-cell polarization + GOC:TermGenie + + + + + up-regulation of establishment of T cell polarity + GOC:TermGenie + + + + + up-regulation of establishment of T lymphocyte polarity + GOC:TermGenie + + + + + up-regulation of establishment of T-cell polarity + GOC:TermGenie + + + + + up-regulation of establishment of T-lymphocyte polarity + GOC:TermGenie + + + + + upregulation of T cell polarization + GOC:TermGenie + + + + + upregulation of T lymphocyte polarization + GOC:TermGenie + + + + + upregulation of T-cell polarization + GOC:TermGenie + + + + + upregulation of establishment of T cell polarity + GOC:TermGenie + + + + + upregulation of establishment of T lymphocyte polarity + GOC:TermGenie + + + + + upregulation of establishment of T-cell polarity + GOC:TermGenie + + + + + upregulation of establishment of T-lymphocyte polarity + GOC:TermGenie + + + + + activation of T cell polarization + GOC:TermGenie + + + + + activation of T lymphocyte polarization + GOC:TermGenie + + + + + activation of T-cell polarization + GOC:TermGenie + + + + + activation of establishment of T cell polarity + GOC:TermGenie + + + + + activation of establishment of T lymphocyte polarity + GOC:TermGenie + + + + + activation of establishment of T-cell polarity + GOC:TermGenie + + + + + activation of establishment of T-lymphocyte polarity + GOC:TermGenie + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a primary palate over time, from its formation to the mature structure. + cls + 2015-02-11T22:42:38Z + primary palate process development + biological_process + palatum primarium development + primitive palate development + processus palatinus medianus development + GO:1903929 + primary palate development + + + + + The process whose specific outcome is the progression of a primary palate over time, from its formation to the mature structure. + GOC:TermGenie + GOC:mgi_curators + GO_REF:0000094 + PMID:24644145 + PMID:25504820 + + + + + primary palate process development + GOC:TermGenie + + + + + palatum primarium development + GOC:TermGenie + + + + + primitive palate development + GOC:TermGenie + + + + + processus palatinus medianus development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of respiratory gaseous exchange. + sl + 2015-02-17T20:26:24Z + down regulation of respiratory gaseous exchange + down-regulation of respiratory gaseous exchange + downregulation of respiratory gaseous exchange + inhibition of respiratory gaseous exchange + biological_process + GO:1903941 + negative regulation of respiratory gaseous exchange + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of respiratory gaseous exchange. + GOC:TermGenie + GO_REF:0000058 + PMID:22819705 + + + + + down regulation of respiratory gaseous exchange + GOC:TermGenie + + + + + down-regulation of respiratory gaseous exchange + GOC:TermGenie + + + + + downregulation of respiratory gaseous exchange + GOC:TermGenie + + + + + inhibition of respiratory gaseous exchange + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of respiratory gaseous exchange. + sl + 2015-02-17T20:26:35Z + up regulation of respiratory gaseous exchange + up-regulation of respiratory gaseous exchange + upregulation of respiratory gaseous exchange + activation of respiratory gaseous exchange + biological_process + GO:1903942 + positive regulation of respiratory gaseous exchange + + + + + Any process that activates or increases the frequency, rate or extent of respiratory gaseous exchange. + GOC:TermGenie + GO_REF:0000058 + PMID:22819705 + + + + + up regulation of respiratory gaseous exchange + GOC:TermGenie + + + + + up-regulation of respiratory gaseous exchange + GOC:TermGenie + + + + + upregulation of respiratory gaseous exchange + GOC:TermGenie + + + + + activation of respiratory gaseous exchange + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of glial cell migration. + nc + 2015-03-02T15:13:31Z + regulation of glia cell migration + biological_process + GO:1903975 + regulation of glial cell migration + + + + + Any process that modulates the frequency, rate or extent of glial cell migration. + GOC:BHF + GOC:TermGenie + GOC:nc + GO_REF:0000058 + PMID:19100238 + + + + + regulation of glia cell migration + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of glial cell migration. + nc + 2015-03-02T15:13:38Z + down regulation of glia cell migration + down regulation of glial cell migration + down-regulation of glia cell migration + down-regulation of glial cell migration + downregulation of glia cell migration + downregulation of glial cell migration + negative regulation of glia cell migration + inhibition of glia cell migration + inhibition of glial cell migration + biological_process + GO:1903976 + negative regulation of glial cell migration + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of glial cell migration. + GOC:BHF + GOC:TermGenie + GOC:nc + GO_REF:0000058 + PMID:19100238 + + + + + down regulation of glia cell migration + GOC:TermGenie + + + + + down regulation of glial cell migration + GOC:TermGenie + + + + + down-regulation of glia cell migration + GOC:TermGenie + + + + + down-regulation of glial cell migration + GOC:TermGenie + + + + + downregulation of glia cell migration + GOC:TermGenie + + + + + downregulation of glial cell migration + GOC:TermGenie + + + + + negative regulation of glia cell migration + GOC:TermGenie + + + + + inhibition of glia cell migration + GOC:TermGenie + + + + + inhibition of glial cell migration + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of glial cell migration. + nc + 2015-03-02T15:13:43Z + positive regulation of glia cell migration + up regulation of glia cell migration + up regulation of glial cell migration + up-regulation of glia cell migration + up-regulation of glial cell migration + upregulation of glia cell migration + upregulation of glial cell migration + activation of glia cell migration + activation of glial cell migration + biological_process + GO:1903977 + positive regulation of glial cell migration + + + + + Any process that activates or increases the frequency, rate or extent of glial cell migration. + GOC:BHF + GOC:TermGenie + GOC:nc + GO_REF:0000058 + PMID:19100238 + + + + + positive regulation of glia cell migration + GOC:TermGenie + + + + + up regulation of glia cell migration + GOC:TermGenie + + + + + up regulation of glial cell migration + GOC:TermGenie + + + + + up-regulation of glia cell migration + GOC:TermGenie + + + + + up-regulation of glial cell migration + GOC:TermGenie + + + + + upregulation of glia cell migration + GOC:TermGenie + + + + + upregulation of glial cell migration + GOC:TermGenie + + + + + activation of glia cell migration + GOC:TermGenie + + + + + activation of glial cell migration + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus. + sl + 2015-03-06T19:33:54Z + biological_process + GO:1904014 + response to serotonin + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus. + GOC:TermGenie + GO_REF:0000071 + PMID:1505525 + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus. + sl + 2015-03-06T19:34:00Z + biological_process + GO:1904015 + cellular response to serotonin + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus. + GOC:TermGenie + GO_REF:0000071 + PMID:1505525 + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of vasculature development. + sl + 2015-03-06T22:17:04Z + up regulation of vasculature development + up-regulation of vasculature development + upregulation of vasculature development + activation of vasculature development + biological_process + activation of vascular system development + positive regulation of vascular system development + up regulation of vascular system development + up-regulation of vascular system development + upregulation of vascular system development + GO:1904018 + positive regulation of vasculature development + + + + + Any process that activates or increases the frequency, rate or extent of vasculature development. + GOC:TermGenie + GO_REF:0000058 + PMID:21472453 + + + + + up regulation of vasculature development + GOC:TermGenie + + + + + up-regulation of vasculature development + GOC:TermGenie + + + + + upregulation of vasculature development + GOC:TermGenie + + + + + activation of vasculature development + GOC:TermGenie + + + + + activation of vascular system development + GOC:TermGenie + + + + + positive regulation of vascular system development + GOC:TermGenie + + + + + up regulation of vascular system development + GOC:TermGenie + + + + + up-regulation of vascular system development + GOC:TermGenie + + + + + upregulation of vascular system development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of collagen fibril organization. + ae + 2015-03-12T12:36:52Z + regulation of collagen fibril organisation + regulation of fibrillar collagen organization + biological_process + regulation of collagen fibrillogenesis + GO:1904026 + regulation of collagen fibril organization + + + + + Any process that modulates the frequency, rate or extent of collagen fibril organization. + GOC:TermGenie + GO_REF:0000058 + PMID:25451920 + + + + + regulation of collagen fibril organisation + GOC:TermGenie + + + + + regulation of fibrillar collagen organization + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of collagen fibril organization. + ae + 2015-03-12T12:36:59Z + down regulation of collagen fibril organisation + down regulation of collagen fibril organization + down regulation of fibrillar collagen organization + down-regulation of collagen fibril organisation + down-regulation of collagen fibril organization + down-regulation of fibrillar collagen organization + downregulation of collagen fibril organisation + downregulation of collagen fibril organization + downregulation of fibrillar collagen organization + negative regulation of collagen fibril organisation + negative regulation of fibrillar collagen organization + inhibition of collagen fibril organisation + inhibition of collagen fibril organization + inhibition of fibrillar collagen organization + biological_process + GO:1904027 + negative regulation of collagen fibril organization + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of collagen fibril organization. + GOC:TermGenie + GO_REF:0000058 + PMID:25451920 + + + + + down regulation of collagen fibril organisation + GOC:TermGenie + + + + + down regulation of collagen fibril organization + GOC:TermGenie + + + + + down regulation of fibrillar collagen organization + GOC:TermGenie + + + + + down-regulation of collagen fibril organisation + GOC:TermGenie + + + + + down-regulation of collagen fibril organization + GOC:TermGenie + + + + + down-regulation of fibrillar collagen organization + GOC:TermGenie + + + + + downregulation of collagen fibril organisation + GOC:TermGenie + + + + + downregulation of collagen fibril organization + GOC:TermGenie + + + + + downregulation of fibrillar collagen organization + GOC:TermGenie + + + + + negative regulation of collagen fibril organisation + GOC:TermGenie + + + + + negative regulation of fibrillar collagen organization + GOC:TermGenie + + + + + inhibition of collagen fibril organisation + GOC:TermGenie + + + + + inhibition of collagen fibril organization + GOC:TermGenie + + + + + inhibition of fibrillar collagen organization + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of collagen fibril organization. + ae + 2015-03-12T12:37:06Z + positive regulation of collagen fibril organisation + positive regulation of fibrillar collagen organization + up regulation of collagen fibril organisation + up regulation of collagen fibril organization + up regulation of fibrillar collagen organization + up-regulation of collagen fibril organisation + up-regulation of collagen fibril organization + up-regulation of fibrillar collagen organization + upregulation of collagen fibril organisation + upregulation of collagen fibril organization + upregulation of fibrillar collagen organization + activation of collagen fibril organisation + activation of collagen fibril organization + activation of fibrillar collagen organization + biological_process + GO:1904028 + positive regulation of collagen fibril organization + + + + + Any process that activates or increases the frequency, rate or extent of collagen fibril organization. + GOC:TermGenie + GO_REF:0000058 + PMID:25451920 + + + + + positive regulation of collagen fibril organisation + GOC:TermGenie + + + + + positive regulation of fibrillar collagen organization + GOC:TermGenie + + + + + up regulation of collagen fibril organisation + GOC:TermGenie + + + + + up regulation of collagen fibril organization + GOC:TermGenie + + + + + up regulation of fibrillar collagen organization + GOC:TermGenie + + + + + up-regulation of collagen fibril organisation + GOC:TermGenie + + + + + up-regulation of collagen fibril organization + GOC:TermGenie + + + + + up-regulation of fibrillar collagen organization + GOC:TermGenie + + + + + upregulation of collagen fibril organisation + GOC:TermGenie + + + + + upregulation of collagen fibril organization + GOC:TermGenie + + + + + upregulation of fibrillar collagen organization + GOC:TermGenie + + + + + activation of collagen fibril organisation + GOC:TermGenie + + + + + activation of collagen fibril organization + GOC:TermGenie + + + + + activation of fibrillar collagen organization + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldosterone stimulus. + sl + 2015-03-16T23:07:53Z + biological_process + GO:1904044 + response to aldosterone + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldosterone stimulus. + GOC:TermGenie + GO_REF:0000071 + PMID:17644563 + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldosterone stimulus. + sl + 2015-03-16T23:07:59Z + biological_process + GO:1904045 + cellular response to aldosterone + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldosterone stimulus. + GOC:TermGenie + GO_REF:0000071 + PMID:17644563 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of cholangiocyte proliferation. + sl + 2015-03-18T17:56:14Z + regulation of hepatoblast proliferation + biological_process + GO:1904054 + regulation of cholangiocyte proliferation + + + + + Any process that modulates the frequency, rate or extent of cholangiocyte proliferation. + GOC:TermGenie + GO_REF:0000058 + PMID:24434010 + + + + + regulation of hepatoblast proliferation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cholangiocyte proliferation. + sl + 2015-03-18T17:56:20Z + down regulation of cholangiocyte proliferation + down regulation of hepatoblast proliferation + down-regulation of cholangiocyte proliferation + down-regulation of hepatoblast proliferation + downregulation of cholangiocyte proliferation + downregulation of hepatoblast proliferation + negative regulation of hepatoblast proliferation + inhibition of cholangiocyte proliferation + inhibition of hepatoblast proliferation + biological_process + GO:1904055 + negative regulation of cholangiocyte proliferation + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cholangiocyte proliferation. + GOC:TermGenie + GO_REF:0000058 + PMID:24434010 + + + + + down regulation of cholangiocyte proliferation + GOC:TermGenie + + + + + down regulation of hepatoblast proliferation + GOC:TermGenie + + + + + down-regulation of cholangiocyte proliferation + GOC:TermGenie + + + + + down-regulation of hepatoblast proliferation + GOC:TermGenie + + + + + downregulation of cholangiocyte proliferation + GOC:TermGenie + + + + + downregulation of hepatoblast proliferation + GOC:TermGenie + + + + + negative regulation of hepatoblast proliferation + GOC:TermGenie + + + + + inhibition of cholangiocyte proliferation + GOC:TermGenie + + + + + inhibition of hepatoblast proliferation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of cholangiocyte proliferation. + sl + 2015-03-18T17:56:26Z + positive regulation of hepatoblast proliferation + up regulation of cholangiocyte proliferation + up regulation of hepatoblast proliferation + up-regulation of cholangiocyte proliferation + up-regulation of hepatoblast proliferation + upregulation of cholangiocyte proliferation + upregulation of hepatoblast proliferation + activation of cholangiocyte proliferation + activation of hepatoblast proliferation + biological_process + GO:1904056 + positive regulation of cholangiocyte proliferation + + + + + Any process that activates or increases the frequency, rate or extent of cholangiocyte proliferation. + GOC:TermGenie + GO_REF:0000058 + PMID:24434010 + + + + + positive regulation of hepatoblast proliferation + GOC:TermGenie + + + + + up regulation of cholangiocyte proliferation + GOC:TermGenie + + + + + up regulation of hepatoblast proliferation + GOC:TermGenie + + + + + up-regulation of cholangiocyte proliferation + GOC:TermGenie + + + + + up-regulation of hepatoblast proliferation + GOC:TermGenie + + + + + upregulation of cholangiocyte proliferation + GOC:TermGenie + + + + + upregulation of hepatoblast proliferation + GOC:TermGenie + + + + + activation of cholangiocyte proliferation + GOC:TermGenie + + + + + activation of hepatoblast proliferation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of pain. + sl + 2015-03-18T20:33:57Z + down regulation of nociception + down regulation of sensory perception of pain + down-regulation of nociception + down-regulation of sensory perception of pain + downregulation of nociception + downregulation of sensory perception of pain + negative regulation of nociception + down regulation of perception of physiological pain + down-regulation of perception of physiological pain + downregulation of perception of physiological pain + inhibition of nociception + inhibition of perception of physiological pain + inhibition of sensory perception of pain + negative regulation of perception of physiological pain + biological_process + GO:1904057 + negative regulation of sensory perception of pain + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of pain. + GOC:TermGenie + GO_REF:0000058 + PMID:17167094 + + + + + down regulation of nociception + GOC:TermGenie + + + + + down regulation of sensory perception of pain + GOC:TermGenie + + + + + down-regulation of nociception + GOC:TermGenie + + + + + down-regulation of sensory perception of pain + GOC:TermGenie + + + + + downregulation of nociception + GOC:TermGenie + + + + + downregulation of sensory perception of pain + GOC:TermGenie + + + + + negative regulation of nociception + GOC:TermGenie + + + + + down regulation of perception of physiological pain + GOC:TermGenie + + + + + down-regulation of perception of physiological pain + GOC:TermGenie + + + + + downregulation of perception of physiological pain + GOC:TermGenie + + + + + inhibition of nociception + GOC:TermGenie + + + + + inhibition of perception of physiological pain + GOC:TermGenie + + + + + inhibition of sensory perception of pain + GOC:TermGenie + + + + + negative regulation of perception of physiological pain + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of sensory perception of pain. + sl + 2015-03-18T20:34:03Z + positive regulation of nociception + up regulation of nociception + up regulation of sensory perception of pain + up-regulation of nociception + up-regulation of sensory perception of pain + upregulation of nociception + upregulation of sensory perception of pain + activation of nociception + activation of perception of physiological pain + activation of sensory perception of pain + positive regulation of perception of physiological pain + up regulation of perception of physiological pain + up-regulation of perception of physiological pain + upregulation of perception of physiological pain + biological_process + GO:1904058 + positive regulation of sensory perception of pain + + + + + Any process that activates or increases the frequency, rate or extent of sensory perception of pain. + GOC:TermGenie + GO_REF:0000058 + PMID:17167094 + + + + + positive regulation of nociception + GOC:TermGenie + + + + + up regulation of nociception + GOC:TermGenie + + + + + up regulation of sensory perception of pain + GOC:TermGenie + + + + + up-regulation of nociception + GOC:TermGenie + + + + + up-regulation of sensory perception of pain + GOC:TermGenie + + + + + upregulation of nociception + GOC:TermGenie + + + + + upregulation of sensory perception of pain + GOC:TermGenie + + + + + activation of nociception + GOC:TermGenie + + + + + activation of perception of physiological pain + GOC:TermGenie + + + + + activation of sensory perception of pain + GOC:TermGenie + + + + + positive regulation of perception of physiological pain + GOC:TermGenie + + + + + up regulation of perception of physiological pain + GOC:TermGenie + + + + + up-regulation of perception of physiological pain + GOC:TermGenie + + + + + upregulation of perception of physiological pain + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of trophectodermal cell proliferation. + tb + 2015-03-20T16:55:56Z + regulation of trophectoderm cell proliferation + biological_process + GO:1904073 + regulation of trophectodermal cell proliferation + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate or extent of trophectodermal cell proliferation. + GOC:TermGenie + GO_REF:0000058 + PMID:24508636 + + + + + regulation of trophectoderm cell proliferation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of trophectodermal cell proliferation. + tb + 2015-03-20T16:56:02Z + down regulation of trophectoderm cell proliferation + down regulation of trophectodermal cell proliferation + down-regulation of trophectoderm cell proliferation + down-regulation of trophectodermal cell proliferation + downregulation of trophectoderm cell proliferation + downregulation of trophectodermal cell proliferation + negative regulation of trophectoderm cell proliferation + inhibition of trophectoderm cell proliferation + inhibition of trophectodermal cell proliferation + biological_process + GO:1904074 + negative regulation of trophectodermal cell proliferation + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of trophectodermal cell proliferation. + GOC:TermGenie + GO_REF:0000058 + PMID:24508636 + + + + + down regulation of trophectoderm cell proliferation + GOC:TermGenie + + + + + down regulation of trophectodermal cell proliferation + GOC:TermGenie + + + + + down-regulation of trophectoderm cell proliferation + GOC:TermGenie + + + + + down-regulation of trophectodermal cell proliferation + GOC:TermGenie + + + + + downregulation of trophectoderm cell proliferation + GOC:TermGenie + + + + + downregulation of trophectodermal cell proliferation + GOC:TermGenie + + + + + negative regulation of trophectoderm cell proliferation + GOC:TermGenie + + + + + inhibition of trophectoderm cell proliferation + GOC:TermGenie + + + + + inhibition of trophectodermal cell proliferation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of trophectodermal cell proliferation. + tb + 2015-03-20T16:56:08Z + positive regulation of trophectoderm cell proliferation + up regulation of trophectoderm cell proliferation + up regulation of trophectodermal cell proliferation + up-regulation of trophectoderm cell proliferation + up-regulation of trophectodermal cell proliferation + upregulation of trophectoderm cell proliferation + upregulation of trophectodermal cell proliferation + activation of trophectoderm cell proliferation + activation of trophectodermal cell proliferation + biological_process + GO:1904075 + positive regulation of trophectodermal cell proliferation + + + + + Any process that activates or increases the frequency, rate or extent of trophectodermal cell proliferation. + GOC:TermGenie + GO_REF:0000058 + PMID:24508636 + + + + + positive regulation of trophectoderm cell proliferation + GOC:TermGenie + + + + + up regulation of trophectoderm cell proliferation + GOC:TermGenie + + + + + up regulation of trophectodermal cell proliferation + GOC:TermGenie + + + + + up-regulation of trophectoderm cell proliferation + GOC:TermGenie + + + + + up-regulation of trophectodermal cell proliferation + GOC:TermGenie + + + + + upregulation of trophectoderm cell proliferation + GOC:TermGenie + + + + + upregulation of trophectodermal cell proliferation + GOC:TermGenie + + + + + activation of trophectoderm cell proliferation + GOC:TermGenie + + + + + activation of trophectodermal cell proliferation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + A process in which a protein is transported to, or maintained in, a location within a microvillus. + kmv + 2015-04-01T18:14:41Z + protein localisation in microvillus + protein localisation to microvillus + protein localization in microvillus + biological_process + GO:1904106 + protein localization to microvillus + + + + + A process in which a protein is transported to, or maintained in, a location within a microvillus. + GOC:TermGenie + GOC:kmv + GO_REF:0000087 + PMID:25335890 + + + + + protein localisation in microvillus + GOC:TermGenie + + + + + protein localisation to microvillus + GOC:TermGenie + + + + + protein localization in microvillus + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any cytoplasm that is part of a axon. + sl + 2015-04-06T18:13:14Z + axoplasm + cellular_component + GO:1904115 + axon cytoplasm + + + + + Any cytoplasm that is part of a axon. + GOC:TermGenie + GO_REF:0000064 + PMID:18667152 + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vasopressin stimulus. + sl + 2015-04-06T19:39:42Z + biological_process + GO:1904116 + response to vasopressin + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vasopressin stimulus. + GOC:TermGenie + GO_REF:0000071 + PMID:22811487 + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vasopressin stimulus. + sl + 2015-04-06T19:39:48Z + biological_process + GO:1904117 + cellular response to vasopressin + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vasopressin stimulus. + GOC:TermGenie + GO_REF:0000071 + PMID:22811487 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of otic vesicle morphogenesis. + pga + 2015-04-07T14:00:56Z + biological_process + GO:1904118 + regulation of otic vesicle morphogenesis + + + + + Any process that modulates the frequency, rate or extent of otic vesicle morphogenesis. + GOC:TermGenie + GO_REF:0000058 + PMID:25677106 + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of otic vesicle morphogenesis. + pga + 2015-04-07T14:01:02Z + down regulation of otic vesicle morphogenesis + down-regulation of otic vesicle morphogenesis + downregulation of otic vesicle morphogenesis + inhibition of otic vesicle morphogenesis + biological_process + GO:1904119 + negative regulation of otic vesicle morphogenesis + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of otic vesicle morphogenesis. + GOC:TermGenie + GO_REF:0000058 + PMID:25677106 + + + + + down regulation of otic vesicle morphogenesis + GOC:TermGenie + + + + + down-regulation of otic vesicle morphogenesis + GOC:TermGenie + + + + + downregulation of otic vesicle morphogenesis + GOC:TermGenie + + + + + inhibition of otic vesicle morphogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of otic vesicle morphogenesis. + pga + 2015-04-07T14:01:08Z + up regulation of otic vesicle morphogenesis + up-regulation of otic vesicle morphogenesis + upregulation of otic vesicle morphogenesis + activation of otic vesicle morphogenesis + biological_process + GO:1904120 + positive regulation of otic vesicle morphogenesis + + + + + Any process that activates or increases the frequency, rate or extent of otic vesicle morphogenesis. + GOC:TermGenie + GO_REF:0000058 + PMID:25677106 + + + + + up regulation of otic vesicle morphogenesis + GOC:TermGenie + + + + + up-regulation of otic vesicle morphogenesis + GOC:TermGenie + + + + + upregulation of otic vesicle morphogenesis + GOC:TermGenie + + + + + activation of otic vesicle morphogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation. + tb + 2015-04-14T15:59:22Z + down regulation of meiotic cell cycle process involved in oocyte maturation + down-regulation of meiotic cell cycle process involved in oocyte maturation + downregulation of meiotic cell cycle process involved in oocyte maturation + inhibition of meiotic cell cycle process involved in oocyte maturation + biological_process + GO:1904145 + negative regulation of meiotic cell cycle process involved in oocyte maturation + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation. + GOC:TermGenie + GO_REF:0000058 + PMID:22674394 + + + + + down regulation of meiotic cell cycle process involved in oocyte maturation + GOC:TermGenie + + + + + down-regulation of meiotic cell cycle process involved in oocyte maturation + GOC:TermGenie + + + + + downregulation of meiotic cell cycle process involved in oocyte maturation + GOC:TermGenie + + + + + inhibition of meiotic cell cycle process involved in oocyte maturation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation. + tb + 2015-04-14T15:59:28Z + up regulation of meiotic cell cycle process involved in oocyte maturation + up-regulation of meiotic cell cycle process involved in oocyte maturation + upregulation of meiotic cell cycle process involved in oocyte maturation + activation of meiotic cell cycle process involved in oocyte maturation + biological_process + GO:1904146 + positive regulation of meiotic cell cycle process involved in oocyte maturation + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that activates or increases the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation. + GOC:TermGenie + GO_REF:0000058 + PMID:22674394 + + + + + up regulation of meiotic cell cycle process involved in oocyte maturation + GOC:TermGenie + + + + + up-regulation of meiotic cell cycle process involved in oocyte maturation + GOC:TermGenie + + + + + upregulation of meiotic cell cycle process involved in oocyte maturation + GOC:TermGenie + + + + + activation of meiotic cell cycle process involved in oocyte maturation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of adipose tissue development. + sl + 2015-04-29T20:01:01Z + biological_process + regulation of adipogenesis + GO:1904177 + regulation of adipose tissue development + + + + + Any process that modulates the frequency, rate or extent of adipose tissue development. + GOC:TermGenie + GO_REF:0000058 + PMID:23081848 + + + + + regulation of adipogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of adipose tissue development. + sl + 2015-04-29T20:01:07Z + down regulation of adipose tissue development + down-regulation of adipose tissue development + downregulation of adipose tissue development + inhibition of adipose tissue development + biological_process + down regulation of adipogenesis + down-regulation of adipogenesis + downregulation of adipogenesis + inhibition of adipogenesis + negative regulation of adipogenesis + GO:1904178 + negative regulation of adipose tissue development + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of adipose tissue development. + GOC:TermGenie + GO_REF:0000058 + PMID:23081848 + + + + + down regulation of adipose tissue development + GOC:TermGenie + + + + + down-regulation of adipose tissue development + GOC:TermGenie + + + + + downregulation of adipose tissue development + GOC:TermGenie + + + + + inhibition of adipose tissue development + GOC:TermGenie + + + + + down regulation of adipogenesis + GOC:TermGenie + + + + + down-regulation of adipogenesis + GOC:TermGenie + + + + + downregulation of adipogenesis + GOC:TermGenie + + + + + inhibition of adipogenesis + GOC:TermGenie + + + + + negative regulation of adipogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of adipose tissue development. + sl + 2015-04-29T20:01:13Z + up regulation of adipose tissue development + up-regulation of adipose tissue development + upregulation of adipose tissue development + activation of adipose tissue development + biological_process + activation of adipogenesis + positive regulation of adipogenesis + up regulation of adipogenesis + up-regulation of adipogenesis + upregulation of adipogenesis + GO:1904179 + positive regulation of adipose tissue development + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that activates or increases the frequency, rate or extent of adipose tissue development. + GOC:TermGenie + GO_REF:0000058 + PMID:23081848 + + + + + up regulation of adipose tissue development + GOC:TermGenie + + + + + up-regulation of adipose tissue development + GOC:TermGenie + + + + + upregulation of adipose tissue development + GOC:TermGenie + + + + + activation of adipose tissue development + GOC:TermGenie + + + + + activation of adipogenesis + GOC:TermGenie + + + + + positive regulation of adipogenesis + GOC:TermGenie + + + + + up regulation of adipogenesis + GOC:TermGenie + + + + + up-regulation of adipogenesis + GOC:TermGenie + + + + + upregulation of adipogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of granulosa cell proliferation. + sl + 2015-05-07T17:02:25Z + biological_process + GO:1904195 + regulation of granulosa cell proliferation + + + + + Any process that modulates the frequency, rate or extent of granulosa cell proliferation. + GOC:TermGenie + GO_REF:0000058 + PMID:22383759 + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of granulosa cell proliferation. + sl + 2015-05-07T17:02:34Z + down regulation of granulosa cell proliferation + down-regulation of granulosa cell proliferation + downregulation of granulosa cell proliferation + inhibition of granulosa cell proliferation + biological_process + GO:1904196 + negative regulation of granulosa cell proliferation + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of granulosa cell proliferation. + GOC:TermGenie + GO_REF:0000058 + PMID:22383759 + + + + + down regulation of granulosa cell proliferation + GOC:TermGenie + + + + + down-regulation of granulosa cell proliferation + GOC:TermGenie + + + + + downregulation of granulosa cell proliferation + GOC:TermGenie + + + + + inhibition of granulosa cell proliferation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of granulosa cell proliferation. + sl + 2015-05-07T17:02:40Z + up regulation of granulosa cell proliferation + up-regulation of granulosa cell proliferation + upregulation of granulosa cell proliferation + activation of granulosa cell proliferation + biological_process + GO:1904197 + positive regulation of granulosa cell proliferation + + + + + Any process that activates or increases the frequency, rate or extent of granulosa cell proliferation. + GOC:TermGenie + GO_REF:0000058 + PMID:22383759 + + + + + up regulation of granulosa cell proliferation + GOC:TermGenie + + + + + up-regulation of granulosa cell proliferation + GOC:TermGenie + + + + + upregulation of granulosa cell proliferation + GOC:TermGenie + + + + + activation of granulosa cell proliferation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of skeletal muscle hypertrophy. + sl + 2015-05-08T17:38:13Z + biological_process + GO:1904204 + regulation of skeletal muscle hypertrophy + + + + + Any process that modulates the frequency, rate or extent of skeletal muscle hypertrophy. + GOC:TermGenie + GO_REF:0000058 + PMID:23470307 + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle hypertrophy. + sl + 2015-05-08T17:38:19Z + down regulation of skeletal muscle hypertrophy + down-regulation of skeletal muscle hypertrophy + downregulation of skeletal muscle hypertrophy + inhibition of skeletal muscle hypertrophy + biological_process + GO:1904205 + negative regulation of skeletal muscle hypertrophy + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle hypertrophy. + GOC:TermGenie + GO_REF:0000058 + PMID:23470307 + + + + + down regulation of skeletal muscle hypertrophy + GOC:TermGenie + + + + + down-regulation of skeletal muscle hypertrophy + GOC:TermGenie + + + + + downregulation of skeletal muscle hypertrophy + GOC:TermGenie + + + + + inhibition of skeletal muscle hypertrophy + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of skeletal muscle hypertrophy. + sl + 2015-05-08T17:38:25Z + up regulation of skeletal muscle hypertrophy + up-regulation of skeletal muscle hypertrophy + upregulation of skeletal muscle hypertrophy + activation of skeletal muscle hypertrophy + biological_process + GO:1904206 + positive regulation of skeletal muscle hypertrophy + + + + + Any process that activates or increases the frequency, rate or extent of skeletal muscle hypertrophy. + GOC:TermGenie + GO_REF:0000058 + PMID:23470307 + + + + + up regulation of skeletal muscle hypertrophy + GOC:TermGenie + + + + + up-regulation of skeletal muscle hypertrophy + GOC:TermGenie + + + + + upregulation of skeletal muscle hypertrophy + GOC:TermGenie + + + + + activation of skeletal muscle hypertrophy + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of bile acid metabolic process. + bf + 2015-05-20T11:04:28Z + regulation of bile acid metabolism + biological_process + GO:1904251 + regulation of bile acid metabolic process + + + + + Any process that modulates the frequency, rate or extent of bile acid metabolic process. + GOC:TermGenie + GOC:bf + GO_REF:0000058 + + + + + regulation of bile acid metabolism + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of bile acid metabolic process. + bf + 2015-05-20T11:04:35Z + down regulation of bile acid metabolic process + down regulation of bile acid metabolism + down-regulation of bile acid metabolic process + down-regulation of bile acid metabolism + downregulation of bile acid metabolic process + downregulation of bile acid metabolism + negative regulation of bile acid metabolism + inhibition of bile acid metabolic process + inhibition of bile acid metabolism + biological_process + GO:1904252 + negative regulation of bile acid metabolic process + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of bile acid metabolic process. + GOC:TermGenie + GOC:bf + GO_REF:0000058 + + + + + down regulation of bile acid metabolic process + GOC:TermGenie + + + + + down regulation of bile acid metabolism + GOC:TermGenie + + + + + down-regulation of bile acid metabolic process + GOC:TermGenie + + + + + down-regulation of bile acid metabolism + GOC:TermGenie + + + + + downregulation of bile acid metabolic process + GOC:TermGenie + + + + + downregulation of bile acid metabolism + GOC:TermGenie + + + + + negative regulation of bile acid metabolism + GOC:TermGenie + + + + + inhibition of bile acid metabolic process + GOC:TermGenie + + + + + inhibition of bile acid metabolism + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of bile acid metabolic process. + bf + 2015-05-20T11:04:40Z + positive regulation of bile acid metabolism + up regulation of bile acid metabolic process + up regulation of bile acid metabolism + up-regulation of bile acid metabolic process + up-regulation of bile acid metabolism + upregulation of bile acid metabolic process + upregulation of bile acid metabolism + activation of bile acid metabolic process + activation of bile acid metabolism + biological_process + GO:1904253 + positive regulation of bile acid metabolic process + + + + + Any process that activates or increases the frequency, rate or extent of bile acid metabolic process. + GOC:TermGenie + GOC:bf + GO_REF:0000058 + + + + + positive regulation of bile acid metabolism + GOC:TermGenie + + + + + up regulation of bile acid metabolic process + GOC:TermGenie + + + + + up regulation of bile acid metabolism + GOC:TermGenie + + + + + up-regulation of bile acid metabolic process + GOC:TermGenie + + + + + up-regulation of bile acid metabolism + GOC:TermGenie + + + + + upregulation of bile acid metabolic process + GOC:TermGenie + + + + + upregulation of bile acid metabolism + GOC:TermGenie + + + + + activation of bile acid metabolic process + GOC:TermGenie + + + + + activation of bile acid metabolism + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + The cell cortex of the leading edge of a cell. + kmv + 2015-05-28T19:16:03Z + cell cortex of cell leading edge + cell cortex of front of cell + cell cortex of leading edge of cell + cellular_component + cell periphery of cell leading edge + cell periphery of front of cell + cell periphery of leading edge of cell + peripheral cytoplasm of cell leading edge + peripheral cytoplasm of front of cell + peripheral cytoplasm of leading edge of cell + GO:1904269 + cell leading edge cell cortex + + + + + The cell cortex of the leading edge of a cell. + GOC:TermGenie + GOC:kmv + GO_REF:0000064 + PMID:25843030 + + + + + cell cortex of cell leading edge + GOC:TermGenie + + + + + cell cortex of front of cell + GOC:TermGenie + + + + + cell cortex of leading edge of cell + GOC:TermGenie + + + + + cell periphery of cell leading edge + GOC:TermGenie + + + + + cell periphery of front of cell + GOC:TermGenie + + + + + cell periphery of leading edge of cell + GOC:TermGenie + + + + + peripheral cytoplasm of cell leading edge + GOC:TermGenie + + + + + peripheral cytoplasm of front of cell + GOC:TermGenie + + + + + peripheral cytoplasm of leading edge of cell + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of gastro-intestinal system smooth muscle contraction. + sl + 2015-06-09T23:18:42Z + biological_process + GO:1904304 + regulation of gastro-intestinal system smooth muscle contraction + + + + + Any process that modulates the frequency, rate or extent of gastro-intestinal system smooth muscle contraction. + GOC:TermGenie + GO_REF:0000058 + PMID:10821044 + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of gastro-intestinal system smooth muscle contraction. + sl + 2015-06-09T23:18:48Z + down regulation of gastro-intestinal system smooth muscle contraction + down-regulation of gastro-intestinal system smooth muscle contraction + downregulation of gastro-intestinal system smooth muscle contraction + inhibition of gastro-intestinal system smooth muscle contraction + biological_process + GO:1904305 + negative regulation of gastro-intestinal system smooth muscle contraction + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of gastro-intestinal system smooth muscle contraction. + GOC:TermGenie + GO_REF:0000058 + PMID:10821044 + + + + + down regulation of gastro-intestinal system smooth muscle contraction + GOC:TermGenie + + + + + down-regulation of gastro-intestinal system smooth muscle contraction + GOC:TermGenie + + + + + downregulation of gastro-intestinal system smooth muscle contraction + GOC:TermGenie + + + + + inhibition of gastro-intestinal system smooth muscle contraction + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of gastro-intestinal system smooth muscle contraction. + sl + 2015-06-09T23:18:54Z + up regulation of gastro-intestinal system smooth muscle contraction + up-regulation of gastro-intestinal system smooth muscle contraction + upregulation of gastro-intestinal system smooth muscle contraction + activation of gastro-intestinal system smooth muscle contraction + biological_process + GO:1904306 + positive regulation of gastro-intestinal system smooth muscle contraction + + + + + Any process that activates or increases the frequency, rate or extent of gastro-intestinal system smooth muscle contraction. + GOC:TermGenie + GO_REF:0000058 + PMID:10821044 + + + + + up regulation of gastro-intestinal system smooth muscle contraction + GOC:TermGenie + + + + + up-regulation of gastro-intestinal system smooth muscle contraction + GOC:TermGenie + + + + + upregulation of gastro-intestinal system smooth muscle contraction + GOC:TermGenie + + + + + activation of gastro-intestinal system smooth muscle contraction + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of smooth muscle contraction involved in micturition. + sl + 2015-06-10T18:46:11Z + biological_process + regulation of smooth muscle contraction involved in urination + regulation of urinary bladder smooth muscle contraction involved in micturition + GO:1904318 + regulation of smooth muscle contraction involved in micturition + + + + + Any process that modulates the frequency, rate or extent of smooth muscle contraction involved in micturition. + GOC:TermGenie + GO_REF:0000058 + PMID:18562635 + + + + + regulation of smooth muscle contraction involved in urination + GOC:TermGenie + + + + + regulation of urinary bladder smooth muscle contraction involved in micturition + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle contraction involved in micturition. + sl + 2015-06-10T18:46:17Z + down regulation of smooth muscle contraction involved in micturition + down-regulation of smooth muscle contraction involved in micturition + downregulation of smooth muscle contraction involved in micturition + inhibition of smooth muscle contraction involved in micturition + biological_process + down regulation of smooth muscle contraction involved in urination + down regulation of urinary bladder smooth muscle contraction involved in micturition + down-regulation of smooth muscle contraction involved in urination + down-regulation of urinary bladder smooth muscle contraction involved in micturition + downregulation of smooth muscle contraction involved in urination + downregulation of urinary bladder smooth muscle contraction involved in micturition + inhibition of smooth muscle contraction involved in urination + inhibition of urinary bladder smooth muscle contraction involved in micturition + negative regulation of smooth muscle contraction involved in urination + negative regulation of urinary bladder smooth muscle contraction involved in micturition + GO:1904319 + negative regulation of smooth muscle contraction involved in micturition + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle contraction involved in micturition. + GOC:TermGenie + GO_REF:0000058 + PMID:18562635 + + + + + down regulation of smooth muscle contraction involved in micturition + GOC:TermGenie + + + + + down-regulation of smooth muscle contraction involved in micturition + GOC:TermGenie + + + + + downregulation of smooth muscle contraction involved in micturition + GOC:TermGenie + + + + + inhibition of smooth muscle contraction involved in micturition + GOC:TermGenie + + + + + down regulation of smooth muscle contraction involved in urination + GOC:TermGenie + + + + + down regulation of urinary bladder smooth muscle contraction involved in micturition + GOC:TermGenie + + + + + down-regulation of smooth muscle contraction involved in urination + GOC:TermGenie + + + + + down-regulation of urinary bladder smooth muscle contraction involved in micturition + GOC:TermGenie + + + + + downregulation of smooth muscle contraction involved in urination + GOC:TermGenie + + + + + downregulation of urinary bladder smooth muscle contraction involved in micturition + GOC:TermGenie + + + + + inhibition of smooth muscle contraction involved in urination + GOC:TermGenie + + + + + inhibition of urinary bladder smooth muscle contraction involved in micturition + GOC:TermGenie + + + + + negative regulation of smooth muscle contraction involved in urination + GOC:TermGenie + + + + + negative regulation of urinary bladder smooth muscle contraction involved in micturition + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of smooth muscle contraction involved in micturition. + sl + 2015-06-10T18:46:23Z + up regulation of smooth muscle contraction involved in micturition + up-regulation of smooth muscle contraction involved in micturition + upregulation of smooth muscle contraction involved in micturition + activation of smooth muscle contraction involved in micturition + biological_process + activation of smooth muscle contraction involved in urination + activation of urinary bladder smooth muscle contraction involved in micturition + positive regulation of smooth muscle contraction involved in urination + positive regulation of urinary bladder smooth muscle contraction involved in micturition + up regulation of smooth muscle contraction involved in urination + up regulation of urinary bladder smooth muscle contraction involved in micturition + up-regulation of smooth muscle contraction involved in urination + up-regulation of urinary bladder smooth muscle contraction involved in micturition + upregulation of smooth muscle contraction involved in urination + upregulation of urinary bladder smooth muscle contraction involved in micturition + GO:1904320 + positive regulation of smooth muscle contraction involved in micturition + + + + + Any process that activates or increases the frequency, rate or extent of smooth muscle contraction involved in micturition. + GOC:TermGenie + GO_REF:0000058 + PMID:18562635 + + + + + up regulation of smooth muscle contraction involved in micturition + GOC:TermGenie + + + + + up-regulation of smooth muscle contraction involved in micturition + GOC:TermGenie + + + + + upregulation of smooth muscle contraction involved in micturition + GOC:TermGenie + + + + + activation of smooth muscle contraction involved in micturition + GOC:TermGenie + + + + + activation of smooth muscle contraction involved in urination + GOC:TermGenie + + + + + activation of urinary bladder smooth muscle contraction involved in micturition + GOC:TermGenie + + + + + positive regulation of smooth muscle contraction involved in urination + GOC:TermGenie + + + + + positive regulation of urinary bladder smooth muscle contraction involved in micturition + GOC:TermGenie + + + + + up regulation of smooth muscle contraction involved in urination + GOC:TermGenie + + + + + up regulation of urinary bladder smooth muscle contraction involved in micturition + GOC:TermGenie + + + + + up-regulation of smooth muscle contraction involved in urination + GOC:TermGenie + + + + + up-regulation of urinary bladder smooth muscle contraction involved in micturition + GOC:TermGenie + + + + + upregulation of smooth muscle contraction involved in urination + GOC:TermGenie + + + + + upregulation of urinary bladder smooth muscle contraction involved in micturition + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of dopaminergic neuron differentiation. + sl + 2015-06-11T18:06:19Z + biological_process + GO:1904338 + regulation of dopaminergic neuron differentiation + + + + + Any process that modulates the frequency, rate or extent of dopaminergic neuron differentiation. + GOC:TermGenie + GO_REF:0000058 + PMID:15522889 + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of dopaminergic neuron differentiation. + sl + 2015-06-11T18:06:25Z + down regulation of dopaminergic neuron differentiation + down-regulation of dopaminergic neuron differentiation + downregulation of dopaminergic neuron differentiation + inhibition of dopaminergic neuron differentiation + biological_process + GO:1904339 + negative regulation of dopaminergic neuron differentiation + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of dopaminergic neuron differentiation. + GOC:TermGenie + GO_REF:0000058 + PMID:15522889 + + + + + down regulation of dopaminergic neuron differentiation + GOC:TermGenie + + + + + down-regulation of dopaminergic neuron differentiation + GOC:TermGenie + + + + + downregulation of dopaminergic neuron differentiation + GOC:TermGenie + + + + + inhibition of dopaminergic neuron differentiation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of dopaminergic neuron differentiation. + sl + 2015-06-11T18:06:32Z + up regulation of dopaminergic neuron differentiation + up-regulation of dopaminergic neuron differentiation + upregulation of dopaminergic neuron differentiation + activation of dopaminergic neuron differentiation + biological_process + GO:1904340 + positive regulation of dopaminergic neuron differentiation + + + + + Any process that activates or increases the frequency, rate or extent of dopaminergic neuron differentiation. + GOC:TermGenie + GO_REF:0000058 + PMID:15522889 + + + + + up regulation of dopaminergic neuron differentiation + GOC:TermGenie + + + + + up-regulation of dopaminergic neuron differentiation + GOC:TermGenie + + + + + upregulation of dopaminergic neuron differentiation + GOC:TermGenie + + + + + activation of dopaminergic neuron differentiation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of colon smooth muscle contraction. + sl + 2015-06-11T21:16:58Z + biological_process + GO:1904341 + regulation of colon smooth muscle contraction + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate or extent of colon smooth muscle contraction. + GOC:TermGenie + GO_REF:0000058 + PMID:24170253 + + + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of colon smooth muscle contraction. + sl + 2015-06-11T21:17:05Z + down regulation of colon smooth muscle contraction + down-regulation of colon smooth muscle contraction + downregulation of colon smooth muscle contraction + inhibition of colon smooth muscle contraction + biological_process + GO:1904342 + negative regulation of colon smooth muscle contraction + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of colon smooth muscle contraction. + GOC:TermGenie + GO_REF:0000058 + PMID:24170253 + + + + + down regulation of colon smooth muscle contraction + GOC:TermGenie + + + + + down-regulation of colon smooth muscle contraction + GOC:TermGenie + + + + + downregulation of colon smooth muscle contraction + GOC:TermGenie + + + + + inhibition of colon smooth muscle contraction + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of colon smooth muscle contraction. + sl + 2015-06-11T21:17:11Z + up regulation of colon smooth muscle contraction + up-regulation of colon smooth muscle contraction + upregulation of colon smooth muscle contraction + activation of colon smooth muscle contraction + biological_process + GO:1904343 + positive regulation of colon smooth muscle contraction + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that activates or increases the frequency, rate or extent of colon smooth muscle contraction. + GOC:TermGenie + GO_REF:0000058 + PMID:24170253 + + + + + up regulation of colon smooth muscle contraction + GOC:TermGenie + + + + + up-regulation of colon smooth muscle contraction + GOC:TermGenie + + + + + upregulation of colon smooth muscle contraction + GOC:TermGenie + + + + + activation of colon smooth muscle contraction + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of gastric mucosal blood circulation. + sl + 2015-06-11T21:20:31Z + regulation of stomach mucosal blood circulation + biological_process + GO:1904344 + regulation of gastric mucosal blood circulation + + + + + Any process that modulates the frequency, rate or extent of gastric mucosal blood circulation. + GOC:TermGenie + GO_REF:0000058 + PMID:10807413 + + + + + regulation of stomach mucosal blood circulation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of gastric mucosal blood circulation. + sl + 2015-06-11T21:20:44Z + down regulation of gastric mucosal blood circulation + down regulation of stomach mucosal blood circulation + down-regulation of gastric mucosal blood circulation + down-regulation of stomach mucosal blood circulation + downregulation of gastric mucosal blood circulation + downregulation of stomach mucosal blood circulation + negative regulation of stomach mucosal blood circulation + inhibition of gastric mucosal blood circulation + inhibition of stomach mucosal blood circulation + biological_process + GO:1904345 + negative regulation of gastric mucosal blood circulation + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of gastric mucosal blood circulation. + GOC:TermGenie + GO_REF:0000058 + PMID:10807413 + + + + + down regulation of gastric mucosal blood circulation + GOC:TermGenie + + + + + down regulation of stomach mucosal blood circulation + GOC:TermGenie + + + + + down-regulation of gastric mucosal blood circulation + GOC:TermGenie + + + + + down-regulation of stomach mucosal blood circulation + GOC:TermGenie + + + + + downregulation of gastric mucosal blood circulation + GOC:TermGenie + + + + + downregulation of stomach mucosal blood circulation + GOC:TermGenie + + + + + negative regulation of stomach mucosal blood circulation + GOC:TermGenie + + + + + inhibition of gastric mucosal blood circulation + GOC:TermGenie + + + + + inhibition of stomach mucosal blood circulation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of gastric mucosal blood circulation. + sl + 2015-06-11T21:20:50Z + positive regulation of stomach mucosal blood circulation + up regulation of gastric mucosal blood circulation + up regulation of stomach mucosal blood circulation + up-regulation of gastric mucosal blood circulation + up-regulation of stomach mucosal blood circulation + upregulation of gastric mucosal blood circulation + upregulation of stomach mucosal blood circulation + activation of gastric mucosal blood circulation + activation of stomach mucosal blood circulation + biological_process + GO:1904346 + positive regulation of gastric mucosal blood circulation + + + + + Any process that activates or increases the frequency, rate or extent of gastric mucosal blood circulation. + GOC:TermGenie + GO_REF:0000058 + PMID:10807413 + + + + + positive regulation of stomach mucosal blood circulation + GOC:TermGenie + + + + + up regulation of gastric mucosal blood circulation + GOC:TermGenie + + + + + up regulation of stomach mucosal blood circulation + GOC:TermGenie + + + + + up-regulation of gastric mucosal blood circulation + GOC:TermGenie + + + + + up-regulation of stomach mucosal blood circulation + GOC:TermGenie + + + + + upregulation of gastric mucosal blood circulation + GOC:TermGenie + + + + + upregulation of stomach mucosal blood circulation + GOC:TermGenie + + + + + activation of gastric mucosal blood circulation + GOC:TermGenie + + + + + activation of stomach mucosal blood circulation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of small intestine smooth muscle contraction. + sl + 2015-06-11T21:37:34Z + biological_process + GO:1904347 + regulation of small intestine smooth muscle contraction + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate or extent of small intestine smooth muscle contraction. + GOC:TermGenie + GO_REF:0000058 + PMID:11991626 + + + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of small intestine smooth muscle contraction. + sl + 2015-06-11T21:37:40Z + down regulation of small intestine smooth muscle contraction + down-regulation of small intestine smooth muscle contraction + downregulation of small intestine smooth muscle contraction + inhibition of small intestine smooth muscle contraction + biological_process + GO:1904348 + negative regulation of small intestine smooth muscle contraction + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of small intestine smooth muscle contraction. + GOC:TermGenie + GO_REF:0000058 + PMID:11991626 + + + + + down regulation of small intestine smooth muscle contraction + GOC:TermGenie + + + + + down-regulation of small intestine smooth muscle contraction + GOC:TermGenie + + + + + downregulation of small intestine smooth muscle contraction + GOC:TermGenie + + + + + inhibition of small intestine smooth muscle contraction + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of small intestine smooth muscle contraction. + sl + 2015-06-11T21:37:46Z + up regulation of small intestine smooth muscle contraction + up-regulation of small intestine smooth muscle contraction + upregulation of small intestine smooth muscle contraction + activation of small intestine smooth muscle contraction + biological_process + GO:1904349 + positive regulation of small intestine smooth muscle contraction + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that activates or increases the frequency, rate or extent of small intestine smooth muscle contraction. + GOC:TermGenie + GO_REF:0000058 + PMID:11991626 + + + + + up regulation of small intestine smooth muscle contraction + GOC:TermGenie + + + + + up-regulation of small intestine smooth muscle contraction + GOC:TermGenie + + + + + upregulation of small intestine smooth muscle contraction + GOC:TermGenie + + + + + activation of small intestine smooth muscle contraction + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of protein catabolic process in the vacuole. + rl + 2015-06-12T09:10:36Z + biological_process + regulation of vacuolar protein breakdown + regulation of vacuolar protein catabolic process + regulation of vacuolar protein catabolism + regulation of vacuolar protein degradation + GO:1904350 + regulation of protein catabolic process in the vacuole + + + + + Any process that modulates the frequency, rate or extent of protein catabolic process in the vacuole. + GOC:BHF + GOC:TermGenie + GOC:rl + GO_REF:0000058 + PMID:25635054 + + + + + regulation of vacuolar protein breakdown + GOC:TermGenie + + + + + regulation of vacuolar protein catabolic process + GOC:TermGenie + + + + + regulation of vacuolar protein catabolism + GOC:TermGenie + + + + + regulation of vacuolar protein degradation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process in the vacuole. + rl + 2015-06-12T09:10:42Z + down regulation of protein catabolic process in the vacuole + down-regulation of protein catabolic process in the vacuole + downregulation of protein catabolic process in the vacuole + inhibition of protein catabolic process in the vacuole + biological_process + down regulation of vacuolar protein breakdown + down regulation of vacuolar protein catabolic process + down regulation of vacuolar protein catabolism + down regulation of vacuolar protein degradation + down-regulation of vacuolar protein breakdown + down-regulation of vacuolar protein catabolic process + down-regulation of vacuolar protein catabolism + down-regulation of vacuolar protein degradation + downregulation of vacuolar protein breakdown + downregulation of vacuolar protein catabolic process + downregulation of vacuolar protein catabolism + downregulation of vacuolar protein degradation + inhibition of vacuolar protein breakdown + inhibition of vacuolar protein catabolic process + inhibition of vacuolar protein catabolism + inhibition of vacuolar protein degradation + negative regulation of vacuolar protein breakdown + negative regulation of vacuolar protein catabolic process + negative regulation of vacuolar protein catabolism + negative regulation of vacuolar protein degradation + GO:1904351 + negative regulation of protein catabolic process in the vacuole + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process in the vacuole. + GOC:BHF + GOC:TermGenie + GOC:rl + GO_REF:0000058 + PMID:25635054 + + + + + down regulation of protein catabolic process in the vacuole + GOC:TermGenie + + + + + down-regulation of protein catabolic process in the vacuole + GOC:TermGenie + + + + + downregulation of protein catabolic process in the vacuole + GOC:TermGenie + + + + + inhibition of protein catabolic process in the vacuole + GOC:TermGenie + + + + + down regulation of vacuolar protein breakdown + GOC:TermGenie + + + + + down regulation of vacuolar protein catabolic process + GOC:TermGenie + + + + + down regulation of vacuolar protein catabolism + GOC:TermGenie + + + + + down regulation of vacuolar protein degradation + GOC:TermGenie + + + + + down-regulation of vacuolar protein breakdown + GOC:TermGenie + + + + + down-regulation of vacuolar protein catabolic process + GOC:TermGenie + + + + + down-regulation of vacuolar protein catabolism + GOC:TermGenie + + + + + down-regulation of vacuolar protein degradation + GOC:TermGenie + + + + + downregulation of vacuolar protein breakdown + GOC:TermGenie + + + + + downregulation of vacuolar protein catabolic process + GOC:TermGenie + + + + + downregulation of vacuolar protein catabolism + GOC:TermGenie + + + + + downregulation of vacuolar protein degradation + GOC:TermGenie + + + + + inhibition of vacuolar protein breakdown + GOC:TermGenie + + + + + inhibition of vacuolar protein catabolic process + GOC:TermGenie + + + + + inhibition of vacuolar protein catabolism + GOC:TermGenie + + + + + inhibition of vacuolar protein degradation + GOC:TermGenie + + + + + negative regulation of vacuolar protein breakdown + GOC:TermGenie + + + + + negative regulation of vacuolar protein catabolic process + GOC:TermGenie + + + + + negative regulation of vacuolar protein catabolism + GOC:TermGenie + + + + + negative regulation of vacuolar protein degradation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of protein catabolic process in the vacuole. + rl + 2015-06-12T09:10:49Z + up regulation of protein catabolic process in the vacuole + up-regulation of protein catabolic process in the vacuole + upregulation of protein catabolic process in the vacuole + activation of protein catabolic process in the vacuole + biological_process + activation of vacuolar protein breakdown + activation of vacuolar protein catabolic process + activation of vacuolar protein catabolism + activation of vacuolar protein degradation + positive regulation of vacuolar protein breakdown + positive regulation of vacuolar protein catabolic process + positive regulation of vacuolar protein catabolism + positive regulation of vacuolar protein degradation + up regulation of vacuolar protein breakdown + up regulation of vacuolar protein catabolic process + up regulation of vacuolar protein catabolism + up regulation of vacuolar protein degradation + up-regulation of vacuolar protein breakdown + up-regulation of vacuolar protein catabolic process + up-regulation of vacuolar protein catabolism + up-regulation of vacuolar protein degradation + upregulation of vacuolar protein breakdown + upregulation of vacuolar protein catabolic process + upregulation of vacuolar protein catabolism + upregulation of vacuolar protein degradation + GO:1904352 + positive regulation of protein catabolic process in the vacuole + + + + + Any process that activates or increases the frequency, rate or extent of protein catabolic process in the vacuole. + GOC:BHF + GOC:TermGenie + GOC:rl + GO_REF:0000058 + PMID:25635054 + + + + + up regulation of protein catabolic process in the vacuole + GOC:TermGenie + + + + + up-regulation of protein catabolic process in the vacuole + GOC:TermGenie + + + + + upregulation of protein catabolic process in the vacuole + GOC:TermGenie + + + + + activation of protein catabolic process in the vacuole + GOC:TermGenie + + + + + activation of vacuolar protein breakdown + GOC:TermGenie + + + + + activation of vacuolar protein catabolic process + GOC:TermGenie + + + + + activation of vacuolar protein catabolism + GOC:TermGenie + + + + + activation of vacuolar protein degradation + GOC:TermGenie + + + + + positive regulation of vacuolar protein breakdown + GOC:TermGenie + + + + + positive regulation of vacuolar protein catabolic process + GOC:TermGenie + + + + + positive regulation of vacuolar protein catabolism + GOC:TermGenie + + + + + positive regulation of vacuolar protein degradation + GOC:TermGenie + + + + + up regulation of vacuolar protein breakdown + GOC:TermGenie + + + + + up regulation of vacuolar protein catabolic process + GOC:TermGenie + + + + + up regulation of vacuolar protein catabolism + GOC:TermGenie + + + + + up regulation of vacuolar protein degradation + GOC:TermGenie + + + + + up-regulation of vacuolar protein breakdown + GOC:TermGenie + + + + + up-regulation of vacuolar protein catabolic process + GOC:TermGenie + + + + + up-regulation of vacuolar protein catabolism + GOC:TermGenie + + + + + up-regulation of vacuolar protein degradation + GOC:TermGenie + + + + + upregulation of vacuolar protein breakdown + GOC:TermGenie + + + + + upregulation of vacuolar protein catabolic process + GOC:TermGenie + + + + + upregulation of vacuolar protein catabolism + GOC:TermGenie + + + + + upregulation of vacuolar protein degradation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of calcitonin secretion. + sl + 2015-06-15T17:54:52Z + biological_process + GO:1904362 + regulation of calcitonin secretion + + + + + Any process that modulates the frequency, rate or extent of calcitonin secretion. + GOC:TermGenie + GO_REF:0000058 + PMID:11278900 + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of calcitonin secretion. + sl + 2015-06-15T17:54:58Z + down regulation of calcitonin secretion + down-regulation of calcitonin secretion + downregulation of calcitonin secretion + inhibition of calcitonin secretion + biological_process + GO:1904363 + negative regulation of calcitonin secretion + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of calcitonin secretion. + GOC:TermGenie + GO_REF:0000058 + PMID:11278900 + + + + + down regulation of calcitonin secretion + GOC:TermGenie + + + + + down-regulation of calcitonin secretion + GOC:TermGenie + + + + + downregulation of calcitonin secretion + GOC:TermGenie + + + + + inhibition of calcitonin secretion + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of calcitonin secretion. + sl + 2015-06-15T17:55:05Z + up regulation of calcitonin secretion + up-regulation of calcitonin secretion + upregulation of calcitonin secretion + activation of calcitonin secretion + biological_process + GO:1904364 + positive regulation of calcitonin secretion + + + + + Any process that activates or increases the frequency, rate or extent of calcitonin secretion. + GOC:TermGenie + GO_REF:0000058 + PMID:11278900 + + + + + up regulation of calcitonin secretion + GOC:TermGenie + + + + + up-regulation of calcitonin secretion + GOC:TermGenie + + + + + upregulation of calcitonin secretion + GOC:TermGenie + + + + + activation of calcitonin secretion + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of protein localization to cell periphery. + sl + 2015-06-22T22:09:25Z + biological_process + GO:1904375 + regulation of protein localization to cell periphery + + + + + Any process that modulates the frequency, rate or extent of protein localization to cell periphery. + GOC:TermGenie + GO_REF:0000058 + PMID:18216290 + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell periphery. + sl + 2015-06-22T22:09:32Z + down regulation of protein localization to cell periphery + down-regulation of protein localization to cell periphery + downregulation of protein localization to cell periphery + inhibition of protein localization to cell periphery + biological_process + GO:1904376 + negative regulation of protein localization to cell periphery + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell periphery. + GOC:TermGenie + GO_REF:0000058 + PMID:18216290 + + + + + down regulation of protein localization to cell periphery + GOC:TermGenie + + + + + down-regulation of protein localization to cell periphery + GOC:TermGenie + + + + + downregulation of protein localization to cell periphery + GOC:TermGenie + + + + + inhibition of protein localization to cell periphery + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of protein localization to cell periphery. + sl + 2015-06-22T22:09:37Z + up regulation of protein localization to cell periphery + up-regulation of protein localization to cell periphery + upregulation of protein localization to cell periphery + activation of protein localization to cell periphery + biological_process + GO:1904377 + positive regulation of protein localization to cell periphery + + + + + Any process that activates or increases the frequency, rate or extent of protein localization to cell periphery. + GOC:TermGenie + GO_REF:0000058 + PMID:18216290 + + + + + up regulation of protein localization to cell periphery + GOC:TermGenie + + + + + up-regulation of protein localization to cell periphery + GOC:TermGenie + + + + + upregulation of protein localization to cell periphery + GOC:TermGenie + + + + + activation of protein localization to cell periphery + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Binding to melatonin. + mr + 2015-06-25T19:19:53Z + molecular_function + GO:1904408 + melatonin binding + + + + + Binding to melatonin. + GOC:TermGenie + GOC:mr + GO_REF:0000067 + PMID:10379923 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of cardiac ventricle development. + sl + 2015-06-25T19:52:15Z + biological_process + GO:1904412 + regulation of cardiac ventricle development + + + + + Any process that modulates the frequency, rate or extent of cardiac ventricle development. + GOC:TermGenie + GO_REF:0000058 + PMID:19590510 + + + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle development. + sl + 2015-06-25T19:52:21Z + down regulation of cardiac ventricle development + down-regulation of cardiac ventricle development + downregulation of cardiac ventricle development + inhibition of cardiac ventricle development + biological_process + GO:1904413 + negative regulation of cardiac ventricle development + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle development. + GOC:TermGenie + GO_REF:0000058 + PMID:19590510 + + + + + down regulation of cardiac ventricle development + GOC:TermGenie + + + + + down-regulation of cardiac ventricle development + GOC:TermGenie + + + + + downregulation of cardiac ventricle development + GOC:TermGenie + + + + + inhibition of cardiac ventricle development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of cardiac ventricle development. + sl + 2015-06-25T19:52:27Z + up regulation of cardiac ventricle development + up-regulation of cardiac ventricle development + upregulation of cardiac ventricle development + activation of cardiac ventricle development + biological_process + GO:1904414 + positive regulation of cardiac ventricle development + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that activates or increases the frequency, rate or extent of cardiac ventricle development. + GOC:TermGenie + GO_REF:0000058 + PMID:19590510 + + + + + up regulation of cardiac ventricle development + GOC:TermGenie + + + + + up-regulation of cardiac ventricle development + GOC:TermGenie + + + + + upregulation of cardiac ventricle development + GOC:TermGenie + + + + + activation of cardiac ventricle development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a cloacal gland over time, from its formation to the mature structure. + mr + 2015-07-15T22:14:39Z + biological_process + GO:1904484 + cloacal gland development + + + + + The process whose specific outcome is the progression of a cloacal gland over time, from its formation to the mature structure. + GOC:TermGenie + GOC:mr + GO_REF:0000094 + PMID:18805421 + + + + + + + + + + + + + + + + + + + A process in which a protein is transported to, or maintained in, a location within a ciliary transition zone. + kmv + 2015-07-17T20:43:21Z + protein localisation in ciliary transition zone + protein localisation to ciliary transition zone + protein localization in ciliary transition zone + biological_process + GO:1904491 + protein localization to ciliary transition zone + + + + + A process in which a protein is transported to, or maintained in, a location within a ciliary transition zone. + GOC:TermGenie + GOC:kmv + GO_REF:0000087 + PMID:21422230 + + + + + protein localisation in ciliary transition zone + GOC:TermGenie + + + + + protein localisation to ciliary transition zone + GOC:TermGenie + + + + + protein localization in ciliary transition zone + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of microtubule binding. + als + 2015-07-30T10:32:13Z + biological_process + regulation of microtubule severing activity + regulation of microtubule/chromatin interaction + GO:1904526 + regulation of microtubule binding + + + + + Any process that modulates the frequency, rate or extent of microtubule binding. + GOC:TermGenie + GOC:als + GO_REF:0000059 + PMID:24520051 + + + + + regulation of microtubule severing activity + GOC:TermGenie + + + + + regulation of microtubule/chromatin interaction + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of microtubule binding. + als + 2015-07-30T10:32:29Z + down regulation of microtubule binding + down-regulation of microtubule binding + downregulation of microtubule binding + inhibition of microtubule binding + biological_process + down regulation of microtubule severing activity + down regulation of microtubule/chromatin interaction + down-regulation of microtubule severing activity + down-regulation of microtubule/chromatin interaction + downregulation of microtubule severing activity + downregulation of microtubule/chromatin interaction + inhibition of microtubule severing activity + inhibition of microtubule/chromatin interaction + negative regulation of microtubule severing activity + negative regulation of microtubule/chromatin interaction + GO:1904527 + negative regulation of microtubule binding + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of microtubule binding. + GOC:TermGenie + GOC:als + GO_REF:0000059 + PMID:24520051 + + + + + down regulation of microtubule binding + GOC:TermGenie + + + + + down-regulation of microtubule binding + GOC:TermGenie + + + + + downregulation of microtubule binding + GOC:TermGenie + + + + + inhibition of microtubule binding + GOC:TermGenie + + + + + down regulation of microtubule severing activity + GOC:TermGenie + + + + + down regulation of microtubule/chromatin interaction + GOC:TermGenie + + + + + down-regulation of microtubule severing activity + GOC:TermGenie + + + + + down-regulation of microtubule/chromatin interaction + GOC:TermGenie + + + + + downregulation of microtubule severing activity + GOC:TermGenie + + + + + downregulation of microtubule/chromatin interaction + GOC:TermGenie + + + + + inhibition of microtubule severing activity + GOC:TermGenie + + + + + inhibition of microtubule/chromatin interaction + GOC:TermGenie + + + + + negative regulation of microtubule severing activity + GOC:TermGenie + + + + + negative regulation of microtubule/chromatin interaction + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of microtubule binding. + als + 2015-07-30T10:32:36Z + up regulation of microtubule binding + up-regulation of microtubule binding + upregulation of microtubule binding + activation of microtubule binding + biological_process + activation of microtubule severing activity + activation of microtubule/chromatin interaction + positive regulation of microtubule severing activity + positive regulation of microtubule/chromatin interaction + up regulation of microtubule severing activity + up regulation of microtubule/chromatin interaction + up-regulation of microtubule severing activity + up-regulation of microtubule/chromatin interaction + upregulation of microtubule severing activity + upregulation of microtubule/chromatin interaction + GO:1904528 + positive regulation of microtubule binding + + + + + Any process that activates or increases the frequency, rate or extent of microtubule binding. + GOC:TermGenie + GOC:als + GO_REF:0000059 + PMID:24520051 + + + + + up regulation of microtubule binding + GOC:TermGenie + + + + + up-regulation of microtubule binding + GOC:TermGenie + + + + + upregulation of microtubule binding + GOC:TermGenie + + + + + activation of microtubule binding + GOC:TermGenie + + + + + activation of microtubule severing activity + GOC:TermGenie + + + + + activation of microtubule/chromatin interaction + GOC:TermGenie + + + + + positive regulation of microtubule severing activity + GOC:TermGenie + + + + + positive regulation of microtubule/chromatin interaction + GOC:TermGenie + + + + + up regulation of microtubule severing activity + GOC:TermGenie + + + + + up regulation of microtubule/chromatin interaction + GOC:TermGenie + + + + + up-regulation of microtubule severing activity + GOC:TermGenie + + + + + up-regulation of microtubule/chromatin interaction + GOC:TermGenie + + + + + upregulation of microtubule severing activity + GOC:TermGenie + + + + + upregulation of microtubule/chromatin interaction + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus. + sl + 2015-08-20T16:46:24Z + response to glycoproteins + biological_process + GO:1904587 + response to glycoprotein + + + + + Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus. + GOC:TermGenie + GO_REF:0000071 + PMID:14597422 + + + + + + + + + + + + + + + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus. + sl + 2015-08-20T16:46:30Z + cellular response to glycoproteins + biological_process + GO:1904588 + cellular response to glycoprotein + + + + + Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus. + GOC:TermGenie + GO_REF:0000071 + PMID:14597422 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of lung alveolus development. + sl + 2015-09-03T22:44:44Z + regulation of alveolarization + regulation of alveologenesis + biological_process + GO:1904653 + regulation of lung alveolus development + + + + + Any process that modulates the frequency, rate or extent of lung alveolus development. + GOC:TermGenie + GO_REF:0000058 + PMID:23962064 + + + + + regulation of alveolarization + GOC:TermGenie + + + + + regulation of alveologenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of lung alveolus development. + sl + 2015-09-03T22:44:50Z + down regulation of alveolarization + down regulation of alveologenesis + down regulation of lung alveolus development + down-regulation of alveolarization + down-regulation of alveologenesis + down-regulation of lung alveolus development + downregulation of alveolarization + downregulation of alveologenesis + downregulation of lung alveolus development + negative regulation of alveolarization + negative regulation of alveologenesis + inhibition of alveolarization + inhibition of alveologenesis + inhibition of lung alveolus development + biological_process + GO:1904654 + negative regulation of lung alveolus development + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of lung alveolus development. + GOC:TermGenie + GO_REF:0000058 + PMID:23962064 + + + + + down regulation of alveolarization + GOC:TermGenie + + + + + down regulation of alveologenesis + GOC:TermGenie + + + + + down regulation of lung alveolus development + GOC:TermGenie + + + + + down-regulation of alveolarization + GOC:TermGenie + + + + + down-regulation of alveologenesis + GOC:TermGenie + + + + + down-regulation of lung alveolus development + GOC:TermGenie + + + + + downregulation of alveolarization + GOC:TermGenie + + + + + downregulation of alveologenesis + GOC:TermGenie + + + + + downregulation of lung alveolus development + GOC:TermGenie + + + + + negative regulation of alveolarization + GOC:TermGenie + + + + + negative regulation of alveologenesis + GOC:TermGenie + + + + + inhibition of alveolarization + GOC:TermGenie + + + + + inhibition of alveologenesis + GOC:TermGenie + + + + + inhibition of lung alveolus development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of lung alveolus development. + sl + 2015-09-03T22:44:56Z + positive regulation of alveolarization + positive regulation of alveologenesis + up regulation of alveolarization + up regulation of alveologenesis + up regulation of lung alveolus development + up-regulation of alveolarization + up-regulation of alveologenesis + up-regulation of lung alveolus development + upregulation of alveolarization + upregulation of alveologenesis + upregulation of lung alveolus development + activation of alveolarization + activation of alveologenesis + activation of lung alveolus development + biological_process + GO:1904655 + positive regulation of lung alveolus development + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that activates or increases the frequency, rate or extent of lung alveolus development. + GOC:TermGenie + GO_REF:0000058 + PMID:23962064 + + + + + positive regulation of alveolarization + GOC:TermGenie + + + + + positive regulation of alveologenesis + GOC:TermGenie + + + + + up regulation of alveolarization + GOC:TermGenie + + + + + up regulation of alveologenesis + GOC:TermGenie + + + + + up regulation of lung alveolus development + GOC:TermGenie + + + + + up-regulation of alveolarization + GOC:TermGenie + + + + + up-regulation of alveologenesis + GOC:TermGenie + + + + + up-regulation of lung alveolus development + GOC:TermGenie + + + + + upregulation of alveolarization + GOC:TermGenie + + + + + upregulation of alveologenesis + GOC:TermGenie + + + + + upregulation of lung alveolus development + GOC:TermGenie + + + + + activation of alveolarization + GOC:TermGenie + + + + + activation of alveologenesis + GOC:TermGenie + + + + + activation of lung alveolus development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The developmental process by which a midbrain is generated and organized. + bf + 2015-09-29T09:15:28Z + MB morphogenesis + biological_process + mesencephalon morphogenesis + GO:1904693 + midbrain morphogenesis + + + + + The developmental process by which a midbrain is generated and organized. + GOC:PARL + GOC:TermGenie + GOC:bf + GO_REF:0000083 + PMID:21347250 + + + + + MB morphogenesis + GOC:TermGenie + + + + + mesencephalon morphogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + The developmental process by which an intramembranous bone is generated and organized. + dos + 2015-10-28T11:46:04Z + biological_process + intramembranous bones morphogenesis + membrane bone morphogenesis + GO:1904770 + intramembranous bone morphogenesis + + + + + The developmental process by which an intramembranous bone is generated and organized. + GOC:TermGenie + GO_REF:0000083 + PMID:26399686 + + + + + intramembranous bones morphogenesis + GOC:TermGenie + + + + + membrane bone morphogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of protein localization to cell cortex. + es + 2015-10-29T16:55:01Z + regulation of protein localisation to cell cortex + biological_process + GO:1904776 + An example is cye-1 in C. elegans, UniProt ID O01501 in PMID:17115027. + regulation of protein localization to cell cortex + + + + + Any process that modulates the frequency, rate or extent of protein localization to cell cortex. + GOC:TermGenie + GO_REF:0000058 + PMID:17115027 + + + + + regulation of protein localisation to cell cortex + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell cortex. + es + 2015-10-29T16:55:08Z + down regulation of protein localisation to cell cortex + down regulation of protein localization to cell cortex + down-regulation of protein localisation to cell cortex + down-regulation of protein localization to cell cortex + downregulation of protein localisation to cell cortex + downregulation of protein localization to cell cortex + negative regulation of protein localisation to cell cortex + inhibition of protein localisation to cell cortex + inhibition of protein localization to cell cortex + biological_process + GO:1904777 + An example is cye-1 in C. elegans, UniProt ID O01501 in PMID:17115027. + negative regulation of protein localization to cell cortex + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell cortex. + GOC:TermGenie + GO_REF:0000058 + PMID:17115027 + + + + + down regulation of protein localisation to cell cortex + GOC:TermGenie + + + + + down regulation of protein localization to cell cortex + GOC:TermGenie + + + + + down-regulation of protein localisation to cell cortex + GOC:TermGenie + + + + + down-regulation of protein localization to cell cortex + GOC:TermGenie + + + + + downregulation of protein localisation to cell cortex + GOC:TermGenie + + + + + downregulation of protein localization to cell cortex + GOC:TermGenie + + + + + negative regulation of protein localisation to cell cortex + GOC:TermGenie + + + + + inhibition of protein localisation to cell cortex + GOC:TermGenie + + + + + inhibition of protein localization to cell cortex + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of protein localization to cell cortex. + es + 2015-10-29T16:55:15Z + positive regulation of protein localisation to cell cortex + up regulation of protein localisation to cell cortex + up regulation of protein localization to cell cortex + up-regulation of protein localisation to cell cortex + up-regulation of protein localization to cell cortex + upregulation of protein localisation to cell cortex + upregulation of protein localization to cell cortex + activation of protein localisation to cell cortex + activation of protein localization to cell cortex + biological_process + GO:1904778 + An example is cye-1 in C. elegans, UniProt ID O01501 in PMID:17115027. + positive regulation of protein localization to cell cortex + + + + + Any process that activates or increases the frequency, rate or extent of protein localization to cell cortex. + GOC:TermGenie + GO_REF:0000058 + PMID:17115027 + + + + + positive regulation of protein localisation to cell cortex + GOC:TermGenie + + + + + up regulation of protein localisation to cell cortex + GOC:TermGenie + + + + + up regulation of protein localization to cell cortex + GOC:TermGenie + + + + + up-regulation of protein localisation to cell cortex + GOC:TermGenie + + + + + up-regulation of protein localization to cell cortex + GOC:TermGenie + + + + + upregulation of protein localisation to cell cortex + GOC:TermGenie + + + + + upregulation of protein localization to cell cortex + GOC:TermGenie + + + + + activation of protein localisation to cell cortex + GOC:TermGenie + + + + + activation of protein localization to cell cortex + GOC:TermGenie + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a serous membrane over time, from its formation to the mature structure. + dph + 2015-11-17T19:00:01Z + tunica serosa development + wall of serous sac development + biological_process + serosa development + GO:1904817 + serous membrane development + + + + + The process whose specific outcome is the progression of a serous membrane over time, from its formation to the mature structure. + GOC:TermGenie + GOC:dph + GO_REF:0000094 + PMID:15840053 + + + + + tunica serosa development + GOC:TermGenie + + + + + wall of serous sac development + GOC:TermGenie + + + + + serosa development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a visceral peritoneum over time, from its formation to the mature structure. + dph + 2015-11-17T19:00:17Z + biological_process + GO:1904818 + visceral peritoneum development + + + + + The process whose specific outcome is the progression of a visceral peritoneum over time, from its formation to the mature structure. + GOC:TermGenie + GOC:dph + GO_REF:0000094 + PMID:15840053 + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a parietal peritoneum over time, from its formation to the mature structure. + dph + 2015-11-17T19:00:24Z + peritoneal cavity lining development + biological_process + GO:1904819 + parietal peritoneum development + + + + + The process whose specific outcome is the progression of a parietal peritoneum over time, from its formation to the mature structure. + GOC:TermGenie + GOC:dph + GO_REF:0000094 + PMID:15840053 + + + + + peritoneal cavity lining development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a peritoneum over time, from its formation to the mature structure. + dph + 2015-11-18T17:23:51Z + biological_process + peritonaeum development + GO:1904820 + peritoneum development + + + + + The process whose specific outcome is the progression of a peritoneum over time, from its formation to the mature structure. + GOC:TermGenie + GOC:dph + GO_REF:0000094 + PMID:15840053 + + + + + peritonaeum development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + The developmental process by which a dorsal root ganglion is generated and organized. + bf + 2015-12-01T16:41:17Z + ganglion of dorsal root morphogenesis + ganglion spinalis morphogenesis + spinal ganglion morphogenesis + spinal ganglion part of peripheral nervous system morphogenesis + biological_process + DRG morphogenesis + dorsal root ganglia morphogenesis + ganglion sensorium nervi spinalis morphogenesis + ganglion spinale morphogenesis + posterior root ganglion morphogenesis + GO:1904835 + dorsal root ganglion morphogenesis + + + + + The developmental process by which a dorsal root ganglion is generated and organized. + GOC:PARL + GOC:TermGenie + GOC:bf + GO_REF:0000083 + PMID:18936100 + + + + + ganglion of dorsal root morphogenesis + GOC:TermGenie + + + + + ganglion spinalis morphogenesis + GOC:TermGenie + + + + + spinal ganglion morphogenesis + GOC:TermGenie + + + + + spinal ganglion part of peripheral nervous system morphogenesis + GOC:TermGenie + + + + + DRG morphogenesis + GOC:TermGenie + + + + + dorsal root ganglia morphogenesis + GOC:TermGenie + + + + + ganglion sensorium nervi spinalis morphogenesis + GOC:TermGenie + + + + + ganglion spinale morphogenesis + GOC:TermGenie + + + + + posterior root ganglion morphogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + The developmental process by which an acoustico-facial VII-VIII ganglion complex is generated and organized. + bf + 2015-12-01T17:02:06Z + acoustico-facial VII-VIII ganglion complex morphogenesis + acousticofacial ganglion morphogenesis + facio-acoustic ganglion complex VII-VIII morphogenesis + facio-acoustic ganglion morphogenesis + biological_process + facio-acoustic VII-VIII ganglion complex morphogenesis + facio-acoustic ganglion complex morphogenesis + GO:1904836 + facioacoustic ganglion morphogenesis + + + + + The developmental process by which an acoustico-facial VII-VIII ganglion complex is generated and organized. + GOC:PARL + GOC:TermGenie + GOC:bf + GOC:mat + GO_REF:0000083 + PMID:18356247 + + + + + acoustico-facial VII-VIII ganglion complex morphogenesis + UBERON:0012175 + + + + + acousticofacial ganglion morphogenesis + GOC:TermGenie + + + + + facio-acoustic ganglion complex VII-VIII morphogenesis + GOC:TermGenie + + + + + facio-acoustic ganglion morphogenesis + GOC:TermGenie + + + + + facio-acoustic VII-VIII ganglion complex morphogenesis + GOC:TermGenie + + + + + facio-acoustic ganglion complex morphogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a ventral tegmental area (VTA) over time, from its formation to the mature structure. + bf + 2015-12-17T14:44:18Z + VTA development + a10a development + ventral tegmental area of tsai development + ventral tegmental nucleus (tsai) development + ventral tegmental nucleus of tsai development + ventral tegmentum development + biological_process + area tegmentalis ventralis (Tsai) development + area tegmentalis ventralis development + tegmentum ventrale development + ventral brain stem development + ventral tegmental area (Tsai) development + ventral tegmental nucleus (Rioch) development + ventromedial mesencephalic tegmentum development + GO:1904866 + ventral tegmental area development + + + + + The process whose specific outcome is the progression of a ventral tegmental area (VTA) over time, from its formation to the mature structure. + GOC:PARL + GOC:TermGenie + GOC:bf + GO_REF:0000094 + PMID:26548362 + + + + + VTA development + GOC:TermGenie + + + + + a10a development + GOC:TermGenie + + + + + ventral tegmental area of tsai development + GOC:TermGenie + + + + + ventral tegmental nucleus (tsai) development + GOC:TermGenie + + + + + ventral tegmental nucleus of tsai development + GOC:TermGenie + + + + + ventral tegmentum development + Wikipedia:Ventral_tegmental_area + + + + + area tegmentalis ventralis (Tsai) development + GOC:TermGenie + + + + + area tegmentalis ventralis development + GOC:TermGenie + + + + + tegmentum ventrale development + GOC:TermGenie + + + + + ventral brain stem development + GOC:TermGenie + + + + + ventral tegmental area (Tsai) development + GOC:TermGenie + + + + + ventral tegmental nucleus (Rioch) development + GOC:TermGenie + + + + + ventromedial mesencephalic tegmentum development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a cranial skeletal system over time, from its formation to the mature structure. The cranial skeletal system is the skeletal subdivision of the head, and includes the skull (cranium plus mandible), pharyngeal and/or hyoid apparatus. + bf + 2016-01-07T13:45:06Z + cranial skeleton development + craniofacial development + osteocranium development + biological_process + cranium development + GO:1904888 + cranial skeletal system development + + + + + The process whose specific outcome is the progression of a cranial skeletal system over time, from its formation to the mature structure. The cranial skeletal system is the skeletal subdivision of the head, and includes the skull (cranium plus mandible), pharyngeal and/or hyoid apparatus. + GOC:PARL + GOC:TermGenie + GOC:bf + GO_REF:0000094 + PMID:11262227 + + + + + cranial skeleton development + GOC:TermGenie + + + + + craniofacial development + PMID:11262227 + + + + + osteocranium development + GOC:TermGenie + + + + + cranium development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of cell proliferation in midbrain. + bf + 2016-02-01T13:16:11Z + regulation of cell proliferation in mesencephalon + biological_process + regulation of mesencepahalic cell proliferation + GO:1904933 + regulation of cell proliferation in midbrain + + + + + Any process that modulates the frequency, rate or extent of cell proliferation in midbrain. + GOC:PARL + GOC:TermGenie + GOC:bf + GO_REF:0000058 + PMID:18953410 + PMID:24431302 + + + + + regulation of cell proliferation in mesencephalon + GOC:TermGenie + + + + + regulation of mesencepahalic cell proliferation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in midbrain. + bf + 2016-02-01T13:16:19Z + down regulation of cell proliferation in mesencephalon + down regulation of cell proliferation in midbrain + down-regulation of cell proliferation in mesencephalon + down-regulation of cell proliferation in midbrain + downregulation of cell proliferation in mesencephalon + downregulation of cell proliferation in midbrain + negative regulation of cell proliferation in mesencephalon + inhibition of cell proliferation in mesencephalon + inhibition of cell proliferation in midbrain + biological_process + down regulation of mesencepahalic cell proliferation + down-regulation of mesencepahalic cell proliferation + downregulation of mesencepahalic cell proliferation + inhibition of mesencepahalic cell proliferation + negative regulation of mesencepahalic cell proliferation + GO:1904934 + negative regulation of cell proliferation in midbrain + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in midbrain. + GOC:PARL + GOC:TermGenie + GOC:bf + GO_REF:0000058 + PMID:18953410 + PMID:24431302 + + + + + down regulation of cell proliferation in mesencephalon + GOC:TermGenie + + + + + down regulation of cell proliferation in midbrain + GOC:TermGenie + + + + + down-regulation of cell proliferation in mesencephalon + GOC:TermGenie + + + + + down-regulation of cell proliferation in midbrain + GOC:TermGenie + + + + + downregulation of cell proliferation in mesencephalon + GOC:TermGenie + + + + + downregulation of cell proliferation in midbrain + GOC:TermGenie + + + + + negative regulation of cell proliferation in mesencephalon + GOC:TermGenie + + + + + inhibition of cell proliferation in mesencephalon + GOC:TermGenie + + + + + inhibition of cell proliferation in midbrain + GOC:TermGenie + + + + + down regulation of mesencepahalic cell proliferation + GOC:TermGenie + + + + + down-regulation of mesencepahalic cell proliferation + GOC:TermGenie + + + + + downregulation of mesencepahalic cell proliferation + GOC:TermGenie + + + + + inhibition of mesencepahalic cell proliferation + GOC:TermGenie + + + + + negative regulation of mesencepahalic cell proliferation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of cell proliferation in midbrain. + bf + 2016-02-01T13:16:27Z + positive regulation of cell proliferation in mesencephalon + up regulation of cell proliferation in mesencephalon + up regulation of cell proliferation in midbrain + up-regulation of cell proliferation in mesencephalon + up-regulation of cell proliferation in midbrain + upregulation of cell proliferation in mesencephalon + upregulation of cell proliferation in midbrain + activation of cell proliferation in mesencephalon + activation of cell proliferation in midbrain + biological_process + activation of mesencepahalic cell proliferation + positive regulation of mesencepahalic cell proliferation + up regulation of mesencepahalic cell proliferation + up-regulation of mesencepahalic cell proliferation + upregulation of mesencepahalic cell proliferation + GO:1904935 + positive regulation of cell proliferation in midbrain + + + + + Any process that activates or increases the frequency, rate or extent of cell proliferation in midbrain. + GOC:PARL + GOC:TermGenie + GOC:bf + GO_REF:0000058 + PMID:24431302 + + + + + positive regulation of cell proliferation in mesencephalon + GOC:TermGenie + + + + + up regulation of cell proliferation in mesencephalon + GOC:TermGenie + + + + + up regulation of cell proliferation in midbrain + GOC:TermGenie + + + + + up-regulation of cell proliferation in mesencephalon + GOC:TermGenie + + + + + up-regulation of cell proliferation in midbrain + GOC:TermGenie + + + + + upregulation of cell proliferation in mesencephalon + GOC:TermGenie + + + + + upregulation of cell proliferation in midbrain + GOC:TermGenie + + + + + activation of cell proliferation in mesencephalon + GOC:TermGenie + + + + + activation of cell proliferation in midbrain + GOC:TermGenie + + + + + activation of mesencepahalic cell proliferation + GOC:TermGenie + + + + + positive regulation of mesencepahalic cell proliferation + GOC:TermGenie + + + + + up regulation of mesencepahalic cell proliferation + GOC:TermGenie + + + + + up-regulation of mesencepahalic cell proliferation + GOC:TermGenie + + + + + upregulation of mesencepahalic cell proliferation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + The orderly movement of an interneuron from one site to another. + ah + 2016-02-01T14:04:32Z + inter neuron migration + inter-neuron migration + biological_process + GO:1904936 + interneuron migration + + + + + The orderly movement of an interneuron from one site to another. + GOC:TermGenie + GOC:ah + GO_REF:0000091 + PMID:18622031 + + + + + inter neuron migration + GOC:ah + + + + + inter-neuron migration + GOC:ah + + + + + + + + + + + + + + + + + + + The orderly movement of a sensory neuron from one site to another. + ah + 2016-02-01T14:15:50Z + biological_process + GO:1904937 + sensory neuron migration + + + + + The orderly movement of a sensory neuron from one site to another. + GOC:TermGenie + GOC:ah + GO_REF:0000091 + PMID:18622031 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of cardiac ventricle formation. + bc + 2016-02-02T16:37:16Z + biological_process + GO:1904942 + regulation of cardiac ventricle formation + + + + + Any process that modulates the frequency, rate or extent of cardiac ventricle formation. + GOC:BHF + GOC:BHF_miRNA + GOC:TermGenie + GOC:bc + GO_REF:0000058 + PMID:23575307 + + + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle formation. + bc + 2016-02-02T16:37:24Z + down regulation of cardiac ventricle formation + down-regulation of cardiac ventricle formation + downregulation of cardiac ventricle formation + inhibition of cardiac ventricle formation + biological_process + GO:1904943 + negative regulation of cardiac ventricle formation + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle formation. + GOC:BHF + GOC:BHF_miRNA + GOC:TermGenie + GOC:bc + GO_REF:0000058 + PMID:23575307 + + + + + down regulation of cardiac ventricle formation + GOC:TermGenie + + + + + down-regulation of cardiac ventricle formation + GOC:TermGenie + + + + + downregulation of cardiac ventricle formation + GOC:TermGenie + + + + + inhibition of cardiac ventricle formation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of cardiac ventricle formation. + bc + 2016-02-02T16:37:31Z + up regulation of cardiac ventricle formation + up-regulation of cardiac ventricle formation + upregulation of cardiac ventricle formation + activation of cardiac ventricle formation + biological_process + GO:1904944 + positive regulation of cardiac ventricle formation + + + + + Any process that activates or increases the frequency, rate or extent of cardiac ventricle formation. + GOC:BHF + GOC:BHF_miRNA + GOC:TermGenie + GOC:bc + GO_REF:0000058 + PMID:23575307 + + + + + up regulation of cardiac ventricle formation + GOC:TermGenie + + + + + up-regulation of cardiac ventricle formation + GOC:TermGenie + + + + + upregulation of cardiac ventricle formation + GOC:TermGenie + + + + + activation of cardiac ventricle formation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization. + mec + 2016-02-05T09:59:24Z + down regulation of establishment of protein localisation + down regulation of establishment of protein localization + down regulation of protein positioning + down regulation of protein recruitment + down-regulation of establishment of protein localisation + down-regulation of establishment of protein localization + down-regulation of protein positioning + down-regulation of protein recruitment + downregulation of establishment of protein localisation + downregulation of establishment of protein localization + downregulation of protein positioning + downregulation of protein recruitment + negative regulation of establishment of protein localisation + negative regulation of protein positioning + negative regulation of protein recruitment + inhibition of establishment of protein localisation + inhibition of establishment of protein localization + inhibition of protein positioning + inhibition of protein recruitment + biological_process + GO:1904950 + negative regulation of establishment of protein localization + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization. + GOC:TermGenie + GO_REF:0000058 + PMID:22761445 + + + + + down regulation of establishment of protein localisation + GOC:TermGenie + + + + + down regulation of establishment of protein localization + GOC:TermGenie + + + + + down regulation of protein positioning + GOC:TermGenie + + + + + down regulation of protein recruitment + GOC:TermGenie + + + + + down-regulation of establishment of protein localisation + GOC:TermGenie + + + + + down-regulation of establishment of protein localization + GOC:TermGenie + + + + + down-regulation of protein positioning + GOC:TermGenie + + + + + down-regulation of protein recruitment + GOC:TermGenie + + + + + downregulation of establishment of protein localisation + GOC:TermGenie + + + + + downregulation of establishment of protein localization + GOC:TermGenie + + + + + downregulation of protein positioning + GOC:TermGenie + + + + + downregulation of protein recruitment + GOC:TermGenie + + + + + negative regulation of establishment of protein localisation + GOC:TermGenie + + + + + negative regulation of protein positioning + GOC:TermGenie + + + + + negative regulation of protein recruitment + GOC:TermGenie + + + + + inhibition of establishment of protein localisation + GOC:TermGenie + + + + + inhibition of establishment of protein localization + GOC:TermGenie + + + + + inhibition of protein positioning + GOC:TermGenie + + + + + inhibition of protein recruitment + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of establishment of protein localization. + mec + 2016-02-05T09:59:32Z + positive regulation of establishment of protein localisation + positive regulation of protein positioning + positive regulation of protein recruitment + up regulation of establishment of protein localisation + up regulation of establishment of protein localization + up regulation of protein positioning + up regulation of protein recruitment + up-regulation of establishment of protein localisation + up-regulation of establishment of protein localization + up-regulation of protein positioning + up-regulation of protein recruitment + upregulation of establishment of protein localisation + upregulation of establishment of protein localization + upregulation of protein positioning + upregulation of protein recruitment + activation of establishment of protein localisation + activation of establishment of protein localization + activation of protein positioning + activation of protein recruitment + biological_process + GO:1904951 + positive regulation of establishment of protein localization + + + + + Any process that activates or increases the frequency, rate or extent of establishment of protein localization. + GOC:TermGenie + GO_REF:0000058 + PMID:22761445 + + + + + positive regulation of establishment of protein localisation + GOC:TermGenie + + + + + positive regulation of protein positioning + GOC:TermGenie + + + + + positive regulation of protein recruitment + GOC:TermGenie + + + + + up regulation of establishment of protein localisation + GOC:TermGenie + + + + + up regulation of establishment of protein localization + GOC:TermGenie + + + + + up regulation of protein positioning + GOC:TermGenie + + + + + up regulation of protein recruitment + GOC:TermGenie + + + + + up-regulation of establishment of protein localisation + GOC:TermGenie + + + + + up-regulation of establishment of protein localization + GOC:TermGenie + + + + + up-regulation of protein positioning + GOC:TermGenie + + + + + up-regulation of protein recruitment + GOC:TermGenie + + + + + upregulation of establishment of protein localisation + GOC:TermGenie + + + + + upregulation of establishment of protein localization + GOC:TermGenie + + + + + upregulation of protein positioning + GOC:TermGenie + + + + + upregulation of protein recruitment + GOC:TermGenie + + + + + activation of establishment of protein localisation + GOC:TermGenie + + + + + activation of establishment of protein localization + GOC:TermGenie + + + + + activation of protein positioning + GOC:TermGenie + + + + + activation of protein recruitment + GOC:TermGenie + + + + + + + + + + + + + + + + + + + The orderly movement of a slow muscle cell from one site to another. + ymb + 2016-02-16T21:20:11Z + slow-twitch muscle cell migration + biological_process + GO:1904969 + The directional migration of a slow muscle cell from one site to another within the embryo. + slow muscle cell migration + + + + + The orderly movement of a slow muscle cell from one site to another. + GOC:TermGenie + GOC:ymb + GO_REF:0000091 + PMID:14667409 + PMID:15572133 + PMID:25534553 + + + + + slow-twitch muscle cell migration + PMID:14667409 + + + + + + + + + + + + + + + + + + + + + + + + + The orderly movement of a lymphatic endothelial cell from one site to another in the wall of a lymphatic vessel. + dgh + 2016-02-18T20:49:43Z + biological_process + GO:1904977 + lymphatic endothelial cell migration + + + + + The orderly movement of a lymphatic endothelial cell from one site to another in the wall of a lymphatic vessel. + GOC:TermGenie + GO_REF:0000091 + PMID:25745057 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of endothelial cell activation. + bc + 2016-02-29T16:16:09Z + biological_process + GO:1904987 + regulation of endothelial cell activation + + + + + Any process that modulates the frequency, rate or extent of endothelial cell activation. + GOC:BHF + GOC:BHF_miRNA + GOC:TermGenie + GOC:bc + GO_REF:0000058 + PMID:24255059 + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell activation. + bc + 2016-02-29T16:16:18Z + down regulation of endothelial cell activation + down-regulation of endothelial cell activation + downregulation of endothelial cell activation + inhibition of endothelial cell activation + biological_process + GO:1904988 + negative regulation of endothelial cell activation + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell activation. + GOC:BHF + GOC:BHF_miRNA + GOC:TermGenie + GOC:bc + GO_REF:0000058 + PMID:24255059 + + + + + down regulation of endothelial cell activation + GOC:TermGenie + + + + + down-regulation of endothelial cell activation + GOC:TermGenie + + + + + downregulation of endothelial cell activation + GOC:TermGenie + + + + + inhibition of endothelial cell activation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of endothelial cell activation. + bc + 2016-02-29T16:16:25Z + up regulation of endothelial cell activation + up-regulation of endothelial cell activation + upregulation of endothelial cell activation + activation of endothelial cell activation + biological_process + GO:1904989 + positive regulation of endothelial cell activation + + + + + Any process that activates or increases the frequency, rate or extent of endothelial cell activation. + GOC:BHF + GOC:BHF_miRNA + GOC:TermGenie + GOC:bc + GO_REF:0000058 + PMID:24255059 + + + + + up regulation of endothelial cell activation + GOC:TermGenie + + + + + up-regulation of endothelial cell activation + GOC:TermGenie + + + + + upregulation of endothelial cell activation + GOC:TermGenie + + + + + activation of endothelial cell activation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of an otic placode over time, from its formation to the mature structure. + bf + 2016-03-10T09:30:20Z + placoda otica development + biological_process + auditory placode development + ear placode development + ear/otic placode development + octaval VIII placode development + octaval placode development + GO:1905040 + otic placode development + + + + + The process whose specific outcome is the progression of an otic placode over time, from its formation to the mature structure. + GOC:PARL + GOC:TermGenie + GOC:bf + GOC:mat + GO_REF:0000094 + PMID:18356247 + + + + + placoda otica development + GOC:TermGenie + + + + + auditory placode development + GOC:TermGenie + + + + + ear placode development + GOC:TermGenie + + + + + ear/otic placode development + GOC:TermGenie + + + + + octaval VIII placode development + GOC:TermGenie + + + + + octaval placode development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of an allantois over time, from its formation to the mature structure. + cls + 2016-03-21T15:18:21Z + biological_process + allantoic bud development + GO:1905069 + allantois development + + + + + The process whose specific outcome is the progression of an allantois over time, from its formation to the mature structure. + GOC:TermGenie + GO_REF:0000094 + PMID:17440924 + PMID:21470579 + + + + + allantoic bud development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of cardiac jelly over time, from its formation to the mature structure. The cardiac jelly is an acellular gelatinous matrix secreted by the myocardium and plays a central role in the septation of the heart. + rl + 2016-03-23T13:17:59Z + heart cardiac jelly development + biological_process + GO:1905072 + cardiac jelly development + + + + + The process whose specific outcome is the progression of cardiac jelly over time, from its formation to the mature structure. The cardiac jelly is an acellular gelatinous matrix secreted by the myocardium and plays a central role in the septation of the heart. + GOC:BHF + GOC:TermGenie + GOC:rl + GO_REF:0000094 + PMID:10645959 + PMID:16314491 + PMID:19703439 + + + + + heart cardiac jelly development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any cell surface receptor signaling pathway that is involved in cell-cell signaling. + dos + 2016-04-06T16:59:57Z + cell surface receptor linked signal transduction involved in cell-cell signaling + cell surface receptor linked signal transduction involved in cell-cell signalling + cell surface receptor linked signaling pathway involved in cell-cell signaling + cell surface receptor linked signaling pathway involved in cell-cell signalling + cell surface receptor linked signalling pathway involved in cell-cell signaling + cell surface receptor linked signalling pathway involved in cell-cell signalling + cell surface receptor signaling pathway involved in cell-cell signalling + biological_process + GO:1905114 + cell surface receptor signaling pathway involved in cell-cell signaling + + + + + Any cell surface receptor signaling pathway that is involved in cell-cell signaling. + GOC:TermGenie + GO_REF:0000060 + ISBN:0-7167-3051-0 + + + + + cell surface receptor linked signal transduction involved in cell-cell signaling + GOC:TermGenie + + + + + cell surface receptor linked signal transduction involved in cell-cell signalling + GOC:TermGenie + + + + + cell surface receptor linked signaling pathway involved in cell-cell signaling + GOC:TermGenie + + + + + cell surface receptor linked signaling pathway involved in cell-cell signalling + GOC:TermGenie + + + + + cell surface receptor linked signalling pathway involved in cell-cell signaling + GOC:TermGenie + + + + + cell surface receptor linked signalling pathway involved in cell-cell signalling + GOC:TermGenie + + + + + cell surface receptor signaling pathway involved in cell-cell signalling + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of axo-dendritic protein transport. + sl + 2016-04-11T20:38:31Z + regulation of axonal protein transport + biological_process + GO:1905126 + regulation of axo-dendritic protein transport + + + + + Any process that modulates the frequency, rate or extent of axo-dendritic protein transport. + GOC:TermGenie + GO_REF:0000058 + PMID:20694152 + + + + + regulation of axonal protein transport + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of axo-dendritic protein transport. + sl + 2016-04-11T20:38:40Z + down regulation of axo-dendritic protein transport + down-regulation of axo-dendritic protein transport + downregulation of axo-dendritic protein transport + down regulation of axonal protein transport + down-regulation of axonal protein transport + downregulation of axonal protein transport + inhibition of axo-dendritic protein transport + inhibition of axonal protein transport + negative regulation of axonal protein transport + biological_process + GO:1905127 + negative regulation of axo-dendritic protein transport + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of axo-dendritic protein transport. + GOC:TermGenie + GO_REF:0000058 + PMID:20694152 + + + + + down regulation of axo-dendritic protein transport + GOC:TermGenie + + + + + down-regulation of axo-dendritic protein transport + GOC:TermGenie + + + + + downregulation of axo-dendritic protein transport + GOC:TermGenie + + + + + down regulation of axonal protein transport + GOC:TermGenie + + + + + down-regulation of axonal protein transport + GOC:TermGenie + + + + + downregulation of axonal protein transport + GOC:TermGenie + + + + + inhibition of axo-dendritic protein transport + GOC:TermGenie + + + + + inhibition of axonal protein transport + GOC:TermGenie + + + + + negative regulation of axonal protein transport + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of axo-dendritic protein transport. + sl + 2016-04-11T20:38:48Z + up regulation of axo-dendritic protein transport + up-regulation of axo-dendritic protein transport + upregulation of axo-dendritic protein transport + activation of axo-dendritic protein transport + activation of axonal protein transport + positive regulation of axonal protein transport + up regulation of axonal protein transport + up-regulation of axonal protein transport + upregulation of axonal protein transport + biological_process + GO:1905128 + positive regulation of axo-dendritic protein transport + + + + + Any process that activates or increases the frequency, rate or extent of axo-dendritic protein transport. + GOC:TermGenie + GO_REF:0000058 + PMID:20694152 + + + + + up regulation of axo-dendritic protein transport + GOC:TermGenie + + + + + up-regulation of axo-dendritic protein transport + GOC:TermGenie + + + + + upregulation of axo-dendritic protein transport + GOC:TermGenie + + + + + activation of axo-dendritic protein transport + GOC:TermGenie + + + + + activation of axonal protein transport + GOC:TermGenie + + + + + positive regulation of axonal protein transport + GOC:TermGenie + + + + + up regulation of axonal protein transport + GOC:TermGenie + + + + + up-regulation of axonal protein transport + GOC:TermGenie + + + + + upregulation of axonal protein transport + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + The process that gives rise to the apical ectodermal ridge. This process pertains to the initial formation of a structure from unspecified parts. + dph + 2016-04-13T11:46:40Z + apical epidermal ridge formation + biological_process + AER formation + crista ectodermalis apicalis formation + GO:1905139 + apical ectodermal ridge formation + + + + + The process that gives rise to the apical ectodermal ridge. This process pertains to the initial formation of a structure from unspecified parts. + GOC:TermGenie + GO_REF:0000081 + PMID:18359901 + PMID:9323126 + PMID:9596583 + + + + + apical epidermal ridge formation + GOC:TermGenie + + + + + AER formation + GOC:TermGenie + + + + + crista ectodermalis apicalis formation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of apical ectodermal ridge formation. + dph + 2016-04-13T12:16:40Z + regulation of apical epidermal ridge formation + biological_process + regulation of AER formation + regulation of crista ectodermalis apicalis formation + GO:1905140 + regulation of apical ectodermal ridge formation + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate or extent of apical ectodermal ridge formation. + GOC:TermGenie + GO_REF:0000058 + PMID:18359901 + + + + + regulation of apical epidermal ridge formation + GOC:TermGenie + + + + + regulation of AER formation + GOC:TermGenie + + + + + regulation of crista ectodermalis apicalis formation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of apical ectodermal ridge formation. + dph + 2016-04-13T12:16:48Z + down regulation of apical ectodermal ridge formation + down regulation of apical epidermal ridge formation + down-regulation of apical ectodermal ridge formation + down-regulation of apical epidermal ridge formation + downregulation of apical ectodermal ridge formation + downregulation of apical epidermal ridge formation + negative regulation of apical epidermal ridge formation + inhibition of apical ectodermal ridge formation + inhibition of apical epidermal ridge formation + biological_process + down regulation of AER formation + down regulation of crista ectodermalis apicalis formation + down-regulation of AER formation + down-regulation of crista ectodermalis apicalis formation + downregulation of AER formation + downregulation of crista ectodermalis apicalis formation + inhibition of AER formation + inhibition of crista ectodermalis apicalis formation + negative regulation of AER formation + negative regulation of crista ectodermalis apicalis formation + GO:1905141 + negative regulation of apical ectodermal ridge formation + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of apical ectodermal ridge formation. + GOC:TermGenie + GO_REF:0000058 + PMID:18359901 + + + + + down regulation of apical ectodermal ridge formation + GOC:TermGenie + + + + + down regulation of apical epidermal ridge formation + GOC:TermGenie + + + + + down-regulation of apical ectodermal ridge formation + GOC:TermGenie + + + + + down-regulation of apical epidermal ridge formation + GOC:TermGenie + + + + + downregulation of apical ectodermal ridge formation + GOC:TermGenie + + + + + downregulation of apical epidermal ridge formation + GOC:TermGenie + + + + + negative regulation of apical epidermal ridge formation + GOC:TermGenie + + + + + inhibition of apical ectodermal ridge formation + GOC:TermGenie + + + + + inhibition of apical epidermal ridge formation + GOC:TermGenie + + + + + down regulation of AER formation + GOC:TermGenie + + + + + down regulation of crista ectodermalis apicalis formation + GOC:TermGenie + + + + + down-regulation of AER formation + GOC:TermGenie + + + + + down-regulation of crista ectodermalis apicalis formation + GOC:TermGenie + + + + + downregulation of AER formation + GOC:TermGenie + + + + + downregulation of crista ectodermalis apicalis formation + GOC:TermGenie + + + + + inhibition of AER formation + GOC:TermGenie + + + + + inhibition of crista ectodermalis apicalis formation + GOC:TermGenie + + + + + negative regulation of AER formation + GOC:TermGenie + + + + + negative regulation of crista ectodermalis apicalis formation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of apical ectodermal ridge formation. + dph + 2016-04-13T12:16:57Z + positive regulation of apical epidermal ridge formation + up regulation of apical ectodermal ridge formation + up regulation of apical epidermal ridge formation + up-regulation of apical ectodermal ridge formation + up-regulation of apical epidermal ridge formation + upregulation of apical ectodermal ridge formation + upregulation of apical epidermal ridge formation + biological_process + activation of AER formation + positive regulation of AER formation + positive regulation of crista ectodermalis apicalis formation + up regulation of AER formation + up regulation of crista ectodermalis apicalis formation + up-regulation of AER formation + up-regulation of crista ectodermalis apicalis formation + upregulation of AER formation + upregulation of crista ectodermalis apicalis formation + GO:1905142 + positive regulation of apical ectodermal ridge formation + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that activates or increases the frequency, rate or extent of apical ectodermal ridge formation. + GOC:TermGenie + GO_REF:0000058 + PMID:18359901 + + + + + positive regulation of apical epidermal ridge formation + GOC:TermGenie + + + + + up regulation of apical ectodermal ridge formation + GOC:TermGenie + + + + + up regulation of apical epidermal ridge formation + GOC:TermGenie + + + + + up-regulation of apical ectodermal ridge formation + GOC:TermGenie + + + + + up-regulation of apical epidermal ridge formation + GOC:TermGenie + + + + + upregulation of apical ectodermal ridge formation + GOC:TermGenie + + + + + upregulation of apical epidermal ridge formation + GOC:TermGenie + + + + + activation of AER formation + GOC:TermGenie + + + + + positive regulation of AER formation + GOC:TermGenie + + + + + positive regulation of crista ectodermalis apicalis formation + GOC:TermGenie + + + + + up regulation of AER formation + GOC:TermGenie + + + + + up regulation of crista ectodermalis apicalis formation + GOC:TermGenie + + + + + up-regulation of AER formation + GOC:TermGenie + + + + + up-regulation of crista ectodermalis apicalis formation + GOC:TermGenie + + + + + upregulation of AER formation + GOC:TermGenie + + + + + upregulation of crista ectodermalis apicalis formation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of smooth muscle hypertrophy. + bc + 2016-04-15T12:47:07Z + biological_process + GO:1905147 + regulation of smooth muscle hypertrophy + + + + + Any process that modulates the frequency, rate or extent of smooth muscle hypertrophy. + GOC:BHF + GOC:BHF_miRNA + GOC:TermGenie + GOC:bc + GO_REF:0000058 + PMID:22161164 + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle hypertrophy. + bc + 2016-04-15T12:47:16Z + down regulation of smooth muscle hypertrophy + down-regulation of smooth muscle hypertrophy + downregulation of smooth muscle hypertrophy + inhibition of smooth muscle hypertrophy + biological_process + GO:1905148 + negative regulation of smooth muscle hypertrophy + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle hypertrophy. + GOC:BHF + GOC:BHF_miRNA + GOC:TermGenie + GOC:bc + GO_REF:0000058 + PMID:22161164 + + + + + down regulation of smooth muscle hypertrophy + GOC:TermGenie + + + + + down-regulation of smooth muscle hypertrophy + GOC:TermGenie + + + + + downregulation of smooth muscle hypertrophy + GOC:TermGenie + + + + + inhibition of smooth muscle hypertrophy + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of smooth muscle hypertrophy. + bc + 2016-04-15T12:47:24Z + up regulation of smooth muscle hypertrophy + up-regulation of smooth muscle hypertrophy + upregulation of smooth muscle hypertrophy + activation of smooth muscle hypertrophy + biological_process + GO:1905149 + positive regulation of smooth muscle hypertrophy + + + + + Any process that activates or increases the frequency, rate or extent of smooth muscle hypertrophy. + GOC:BHF + GOC:BHF_miRNA + GOC:TermGenie + GOC:bc + GO_REF:0000058 + PMID:22161164 + + + + + up regulation of smooth muscle hypertrophy + GOC:TermGenie + + + + + up-regulation of smooth muscle hypertrophy + GOC:TermGenie + + + + + upregulation of smooth muscle hypertrophy + GOC:TermGenie + + + + + activation of smooth muscle hypertrophy + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of cardiocyte differentiation. + bc + 2016-06-02T07:20:01Z + regulation of cardiac cell differentiation + regulation of heart cell differentiation + biological_process + GO:1905207 + regulation of cardiocyte differentiation + + + + + Any process that modulates the frequency, rate or extent of cardiocyte differentiation. + GOC:BHF + GOC:BHF_miRNA + GOC:TermGenie + GOC:bc + GO_REF:0000058 + PMID:23069713 + + + + + regulation of cardiac cell differentiation + GOC:TermGenie + + + + + regulation of heart cell differentiation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cardiocyte differentiation. + bc + 2016-06-02T07:20:09Z + down regulation of cardiac cell differentiation + down regulation of cardiocyte differentiation + down regulation of heart cell differentiation + down-regulation of cardiac cell differentiation + down-regulation of cardiocyte differentiation + down-regulation of heart cell differentiation + downregulation of cardiac cell differentiation + downregulation of cardiocyte differentiation + downregulation of heart cell differentiation + negative regulation of cardiac cell differentiation + negative regulation of heart cell differentiation + inhibition of cardiac cell differentiation + inhibition of cardiocyte differentiation + inhibition of heart cell differentiation + biological_process + GO:1905208 + negative regulation of cardiocyte differentiation + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cardiocyte differentiation. + GOC:BHF + GOC:BHF_miRNA + GOC:TermGenie + GOC:bc + GO_REF:0000058 + PMID:23069713 + + + + + down regulation of cardiac cell differentiation + GOC:TermGenie + + + + + down regulation of cardiocyte differentiation + GOC:TermGenie + + + + + down regulation of heart cell differentiation + GOC:TermGenie + + + + + down-regulation of cardiac cell differentiation + GOC:TermGenie + + + + + down-regulation of cardiocyte differentiation + GOC:TermGenie + + + + + down-regulation of heart cell differentiation + GOC:TermGenie + + + + + downregulation of cardiac cell differentiation + GOC:TermGenie + + + + + downregulation of cardiocyte differentiation + GOC:TermGenie + + + + + downregulation of heart cell differentiation + GOC:TermGenie + + + + + negative regulation of cardiac cell differentiation + GOC:TermGenie + + + + + negative regulation of heart cell differentiation + GOC:TermGenie + + + + + inhibition of cardiac cell differentiation + GOC:TermGenie + + + + + inhibition of cardiocyte differentiation + GOC:TermGenie + + + + + inhibition of heart cell differentiation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of cardiocyte differentiation. + bc + 2016-06-02T07:20:16Z + positive regulation of cardiac cell differentiation + positive regulation of heart cell differentiation + up regulation of cardiac cell differentiation + up regulation of cardiocyte differentiation + up regulation of heart cell differentiation + up-regulation of cardiac cell differentiation + up-regulation of cardiocyte differentiation + up-regulation of heart cell differentiation + upregulation of cardiac cell differentiation + upregulation of cardiocyte differentiation + upregulation of heart cell differentiation + activation of cardiac cell differentiation + activation of cardiocyte differentiation + activation of heart cell differentiation + biological_process + GO:1905209 + positive regulation of cardiocyte differentiation + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that activates or increases the frequency, rate or extent of cardiocyte differentiation. + GOC:BHF + GOC:BHF_miRNA + GOC:TermGenie + GOC:bc + GO_REF:0000058 + PMID:23069713 + + + + + positive regulation of cardiac cell differentiation + GOC:TermGenie + + + + + positive regulation of heart cell differentiation + GOC:TermGenie + + + + + up regulation of cardiac cell differentiation + GOC:TermGenie + + + + + up regulation of cardiocyte differentiation + GOC:TermGenie + + + + + up regulation of heart cell differentiation + GOC:TermGenie + + + + + up-regulation of cardiac cell differentiation + GOC:TermGenie + + + + + up-regulation of cardiocyte differentiation + GOC:TermGenie + + + + + up-regulation of heart cell differentiation + GOC:TermGenie + + + + + upregulation of cardiac cell differentiation + GOC:TermGenie + + + + + upregulation of cardiocyte differentiation + GOC:TermGenie + + + + + upregulation of heart cell differentiation + GOC:TermGenie + + + + + activation of cardiac cell differentiation + GOC:TermGenie + + + + + activation of cardiocyte differentiation + GOC:TermGenie + + + + + activation of heart cell differentiation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of platelet formation. + sl + 2016-06-06T22:15:46Z + regulation of platelet extrusion + biological_process + GO:1905219 + regulation of platelet formation + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate or extent of platelet formation. + GOC:TermGenie + GO_REF:0000058 + PMID:10606160 + + + + + regulation of platelet extrusion + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of platelet formation. + sl + 2016-06-06T22:15:54Z + down regulation of platelet extrusion + down regulation of platelet formation + down-regulation of platelet extrusion + down-regulation of platelet formation + downregulation of platelet extrusion + downregulation of platelet formation + negative regulation of platelet extrusion + inhibition of platelet extrusion + inhibition of platelet formation + biological_process + GO:1905220 + negative regulation of platelet formation + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of platelet formation. + GOC:TermGenie + GO_REF:0000058 + PMID:10606160 + + + + + down regulation of platelet extrusion + GOC:TermGenie + + + + + down regulation of platelet formation + GOC:TermGenie + + + + + down-regulation of platelet extrusion + GOC:TermGenie + + + + + down-regulation of platelet formation + GOC:TermGenie + + + + + downregulation of platelet extrusion + GOC:TermGenie + + + + + downregulation of platelet formation + GOC:TermGenie + + + + + negative regulation of platelet extrusion + GOC:TermGenie + + + + + inhibition of platelet extrusion + GOC:TermGenie + + + + + inhibition of platelet formation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of platelet formation. + sl + 2016-06-06T22:16:02Z + positive regulation of platelet extrusion + up regulation of platelet extrusion + up regulation of platelet formation + up-regulation of platelet extrusion + up-regulation of platelet formation + upregulation of platelet extrusion + upregulation of platelet formation + activation of platelet extrusion + activation of platelet formation + biological_process + GO:1905221 + positive regulation of platelet formation + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that activates or increases the frequency, rate or extent of platelet formation. + GOC:TermGenie + GO_REF:0000058 + PMID:10606160 + + + + + positive regulation of platelet extrusion + GOC:TermGenie + + + + + up regulation of platelet extrusion + GOC:TermGenie + + + + + up regulation of platelet formation + GOC:TermGenie + + + + + up-regulation of platelet extrusion + GOC:TermGenie + + + + + up-regulation of platelet formation + GOC:TermGenie + + + + + upregulation of platelet extrusion + GOC:TermGenie + + + + + upregulation of platelet formation + GOC:TermGenie + + + + + activation of platelet extrusion + GOC:TermGenie + + + + + activation of platelet formation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + The developmental process by which an atrioventricular canal is generated and organized. + rl + 2016-06-07T09:09:51Z + AV canal morphogenesis + AVC morphogenesis + atrial canal morphogenesis + atrio-ventricular canal morphogenesis + biological_process + canalis atrioventricularis morphogenesis + ependymal canal morphogenesis + GO:1905222 + atrioventricular canal morphogenesis + + + + + The developmental process by which an atrioventricular canal is generated and organized. + GOC:BHF + GOC:TermGenie + GOC:rl + GO_REF:0000083 + PMID:19703439 + + + + + AV canal morphogenesis + GOC:TermGenie + + + + + AVC morphogenesis + GOC:TermGenie + + + + + atrial canal morphogenesis + GOC:TermGenie + + + + + atrio-ventricular canal morphogenesis + GOC:TermGenie + + + + + canalis atrioventricularis morphogenesis + GOC:TermGenie + + + + + ependymal canal morphogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + The developmental process by which an epicardium is generated and organized. + rl + 2016-06-07T10:02:32Z + heart epicardium morphogenesis + visceral serous pericardium of heart morphogenesis + visceral serous pericardium proper morphogenesis + biological_process + pericardium visceral mesothelium morphogenesis + GO:1905223 + epicardium morphogenesis + + + + + The developmental process by which an epicardium is generated and organized. + GOC:BHF + GOC:TermGenie + GOC:rl + GO_REF:0000083 + PMID:18718461 + + + + + heart epicardium morphogenesis + GOC:TermGenie + + + + + visceral serous pericardium of heart morphogenesis + GOC:TermGenie + + + + + visceral serous pericardium proper morphogenesis + GOC:TermGenie + + + + + pericardium visceral mesothelium morphogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of epithelial tube formation. + bhm + 2016-06-20T09:35:41Z + biological_process + GO:1905276 + An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay). + regulation of epithelial tube formation + + + + + Any process that modulates the frequency, rate or extent of epithelial tube formation. + GOC:TermGenie + GOC:bhm + GO_REF:0000058 + PMID:25745997 + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of epithelial tube formation. + bhm + 2016-06-20T09:35:49Z + down regulation of epithelial tube formation + down-regulation of epithelial tube formation + downregulation of epithelial tube formation + inhibition of epithelial tube formation + biological_process + GO:1905277 + An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay). + negative regulation of epithelial tube formation + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of epithelial tube formation. + GOC:TermGenie + GOC:bhm + GO_REF:0000058 + PMID:25745997 + + + + + down regulation of epithelial tube formation + GOC:TermGenie + + + + + down-regulation of epithelial tube formation + GOC:TermGenie + + + + + downregulation of epithelial tube formation + GOC:TermGenie + + + + + inhibition of epithelial tube formation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of epithelial tube formation. + bhm + 2016-06-20T09:35:57Z + up regulation of epithelial tube formation + up-regulation of epithelial tube formation + upregulation of epithelial tube formation + activation of epithelial tube formation + biological_process + GO:1905278 + An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay). + positive regulation of epithelial tube formation + + + + + Any process that activates or increases the frequency, rate or extent of epithelial tube formation. + GOC:TermGenie + GOC:bhm + GO_REF:0000058 + PMID:25745997 + + + + + up regulation of epithelial tube formation + GOC:TermGenie + + + + + up-regulation of epithelial tube formation + GOC:TermGenie + + + + + upregulation of epithelial tube formation + GOC:TermGenie + + + + + activation of epithelial tube formation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + The developmental process by which a fibrous ring of heart is generated and organized. + rl + 2016-06-21T09:46:54Z + anulus fibrosus of heart morphogenesis + biological_process + Lower's ring morphogenesis + annulus fibrosus cordis morphogenesis + anulus fibrosus cordis morphogenesis + aortic annulus morphogenesis + atrioventricular ring morphogenesis + coronary tendon morphogenesis + GO:1905285 + fibrous ring of heart morphogenesis + + + + + The developmental process by which a fibrous ring of heart is generated and organized. + GOC:BHF + GOC:TermGenie + GOC:rl + GO_REF:0000083 + PMID:16037571 + + + + + anulus fibrosus of heart morphogenesis + GOC:TermGenie + + + + + Lower's ring morphogenesis + GOC:TermGenie + + + + + annulus fibrosus cordis morphogenesis + GOC:TermGenie + + + + + anulus fibrosus cordis morphogenesis + GOC:TermGenie + + + + + aortic annulus morphogenesis + GOC:TermGenie + + + + + atrioventricular ring morphogenesis + GOC:TermGenie + + + + + coronary tendon morphogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of neural crest cell differentiation. + rl + 2016-06-28T15:02:01Z + biological_process + GO:1905292 + regulation of neural crest cell differentiation + + + + + Any process that modulates the frequency, rate or extent of neural crest cell differentiation. + GOC:BHF + GOC:TermGenie + GOC:rl + GO_REF:0000058 + PMID:15073157 + + + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of neural crest cell differentiation. + rl + 2016-06-28T15:02:09Z + down regulation of neural crest cell differentiation + down-regulation of neural crest cell differentiation + downregulation of neural crest cell differentiation + inhibition of neural crest cell differentiation + biological_process + GO:1905293 + negative regulation of neural crest cell differentiation + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of neural crest cell differentiation. + GOC:BHF + GOC:TermGenie + GOC:rl + GO_REF:0000058 + PMID:15073157 + + + + + down regulation of neural crest cell differentiation + GOC:TermGenie + + + + + down-regulation of neural crest cell differentiation + GOC:TermGenie + + + + + downregulation of neural crest cell differentiation + GOC:TermGenie + + + + + inhibition of neural crest cell differentiation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of neural crest cell differentiation. + rl + 2016-06-28T15:02:16Z + up regulation of neural crest cell differentiation + up-regulation of neural crest cell differentiation + upregulation of neural crest cell differentiation + activation of neural crest cell differentiation + biological_process + GO:1905294 + positive regulation of neural crest cell differentiation + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that activates or increases the frequency, rate or extent of neural crest cell differentiation. + GOC:BHF + GOC:TermGenie + GOC:rl + GO_REF:0000058 + PMID:15073157 + + + + + up regulation of neural crest cell differentiation + GOC:TermGenie + + + + + up-regulation of neural crest cell differentiation + GOC:TermGenie + + + + + upregulation of neural crest cell differentiation + GOC:TermGenie + + + + + activation of neural crest cell differentiation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of cardiac myofibril assembly. + rl + 2016-07-06T10:01:49Z + regulation of cardiac myofibril development + regulation of cardiac myofibril morphogenesis + biological_process + regulation of heart myofibril assembly + GO:1905304 + regulation of cardiac myofibril assembly + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate or extent of cardiac myofibril assembly. + GOC:BHF + GOC:TermGenie + GOC:rl + GO_REF:0000058 + PMID:16151019 + + + + + regulation of cardiac myofibril development + GOC:TermGenie + + + + + regulation of cardiac myofibril morphogenesis + GOC:TermGenie + + + + + regulation of heart myofibril assembly + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cardiac myofibril assembly. + rl + 2016-07-06T10:01:58Z + down regulation of cardiac myofibril assembly + down regulation of cardiac myofibril development + down regulation of cardiac myofibril morphogenesis + down-regulation of cardiac myofibril assembly + down-regulation of cardiac myofibril development + down-regulation of cardiac myofibril morphogenesis + downregulation of cardiac myofibril assembly + downregulation of cardiac myofibril development + downregulation of cardiac myofibril morphogenesis + negative regulation of cardiac myofibril development + negative regulation of cardiac myofibril morphogenesis + inhibition of cardiac myofibril assembly + inhibition of cardiac myofibril development + inhibition of cardiac myofibril morphogenesis + biological_process + down regulation of heart myofibril assembly + down-regulation of heart myofibril assembly + downregulation of heart myofibril assembly + inhibition of heart myofibril assembly + negative regulation of heart myofibril assembly + GO:1905305 + negative regulation of cardiac myofibril assembly + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cardiac myofibril assembly. + GOC:BHF + GOC:TermGenie + GOC:rl + GO_REF:0000058 + PMID:16151019 + + + + + down regulation of cardiac myofibril assembly + GOC:TermGenie + + + + + down regulation of cardiac myofibril development + GOC:TermGenie + + + + + down regulation of cardiac myofibril morphogenesis + GOC:TermGenie + + + + + down-regulation of cardiac myofibril assembly + GOC:TermGenie + + + + + down-regulation of cardiac myofibril development + GOC:TermGenie + + + + + down-regulation of cardiac myofibril morphogenesis + GOC:TermGenie + + + + + downregulation of cardiac myofibril assembly + GOC:TermGenie + + + + + downregulation of cardiac myofibril development + GOC:TermGenie + + + + + downregulation of cardiac myofibril morphogenesis + GOC:TermGenie + + + + + negative regulation of cardiac myofibril development + GOC:TermGenie + + + + + negative regulation of cardiac myofibril morphogenesis + GOC:TermGenie + + + + + inhibition of cardiac myofibril assembly + GOC:TermGenie + + + + + inhibition of cardiac myofibril development + GOC:TermGenie + + + + + inhibition of cardiac myofibril morphogenesis + GOC:TermGenie + + + + + down regulation of heart myofibril assembly + GOC:TermGenie + + + + + down-regulation of heart myofibril assembly + GOC:TermGenie + + + + + downregulation of heart myofibril assembly + GOC:TermGenie + + + + + inhibition of heart myofibril assembly + GOC:TermGenie + + + + + negative regulation of heart myofibril assembly + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of cardiac myofibril assembly. + rl + 2016-07-06T10:02:07Z + positive regulation of cardiac myofibril development + positive regulation of cardiac myofibril morphogenesis + up regulation of cardiac myofibril assembly + up regulation of cardiac myofibril development + up regulation of cardiac myofibril morphogenesis + up-regulation of cardiac myofibril assembly + up-regulation of cardiac myofibril development + up-regulation of cardiac myofibril morphogenesis + upregulation of cardiac myofibril assembly + upregulation of cardiac myofibril development + upregulation of cardiac myofibril morphogenesis + activation of cardiac myofibril assembly + activation of cardiac myofibril development + activation of cardiac myofibril morphogenesis + biological_process + activation of heart myofibril assembly + positive regulation of heart myofibril assembly + up regulation of heart myofibril assembly + up-regulation of heart myofibril assembly + upregulation of heart myofibril assembly + GO:1905306 + positive regulation of cardiac myofibril assembly + + + + + Any process that activates or increases the frequency, rate or extent of cardiac myofibril assembly. + GOC:BHF + GOC:TermGenie + GOC:rl + GO_REF:0000058 + PMID:16151019 + + + + + positive regulation of cardiac myofibril development + GOC:TermGenie + + + + + positive regulation of cardiac myofibril morphogenesis + GOC:TermGenie + + + + + up regulation of cardiac myofibril assembly + GOC:TermGenie + + + + + up regulation of cardiac myofibril development + GOC:TermGenie + + + + + up regulation of cardiac myofibril morphogenesis + GOC:TermGenie + + + + + up-regulation of cardiac myofibril assembly + GOC:TermGenie + + + + + up-regulation of cardiac myofibril development + GOC:TermGenie + + + + + up-regulation of cardiac myofibril morphogenesis + GOC:TermGenie + + + + + upregulation of cardiac myofibril assembly + GOC:TermGenie + + + + + upregulation of cardiac myofibril development + GOC:TermGenie + + + + + upregulation of cardiac myofibril morphogenesis + GOC:TermGenie + + + + + activation of cardiac myofibril assembly + GOC:TermGenie + + + + + activation of cardiac myofibril development + GOC:TermGenie + + + + + activation of cardiac myofibril morphogenesis + GOC:TermGenie + + + + + activation of heart myofibril assembly + GOC:TermGenie + + + + + positive regulation of heart myofibril assembly + GOC:TermGenie + + + + + up regulation of heart myofibril assembly + GOC:TermGenie + + + + + up-regulation of heart myofibril assembly + GOC:TermGenie + + + + + upregulation of heart myofibril assembly + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis. + rl + 2016-07-11T17:34:26Z + biological_process + GO:1905310 + regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis + + + + + Any process that modulates the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis. + GOC:BHF + GOC:TermGenie + GOC:rl + GO_REF:0000058 + PMID:17628518 + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis. + rl + 2016-07-11T17:34:35Z + down regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis + down-regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis + downregulation of cardiac neural crest cell migration involved in outflow tract morphogenesis + inhibition of cardiac neural crest cell migration involved in outflow tract morphogenesis + biological_process + GO:1905311 + negative regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis. + GOC:BHF + GOC:TermGenie + GOC:rl + GO_REF:0000058 + PMID:17628518 + + + + + down regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis + GOC:TermGenie + + + + + down-regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis + GOC:TermGenie + + + + + downregulation of cardiac neural crest cell migration involved in outflow tract morphogenesis + GOC:TermGenie + + + + + inhibition of cardiac neural crest cell migration involved in outflow tract morphogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis. + rl + 2016-07-11T17:34:43Z + up regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis + up-regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis + upregulation of cardiac neural crest cell migration involved in outflow tract morphogenesis + activation of cardiac neural crest cell migration involved in outflow tract morphogenesis + biological_process + GO:1905312 + positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis + + + + + Any process that activates or increases the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis. + GOC:BHF + GOC:TermGenie + GOC:rl + GO_REF:0000058 + PMID:17628518 + + + + + up regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis + GOC:TermGenie + + + + + up-regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis + GOC:TermGenie + + + + + upregulation of cardiac neural crest cell migration involved in outflow tract morphogenesis + GOC:TermGenie + + + + + activation of cardiac neural crest cell migration involved in outflow tract morphogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a semi-lunar valve over time, from its formation to the mature structure. + rl + 2016-07-11T17:50:44Z + semilunar valve development + semilunar valves development + biological_process + GO:1905314 + semi-lunar valve development + + + + + The process whose specific outcome is the progression of a semi-lunar valve over time, from its formation to the mature structure. + GOC:BHF + GOC:TermGenie + GOC:rl + GO_REF:0000094 + PMID:19409885 + + + + + semilunar valve development + GOC:TermGenie + + + + + semilunar valves development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any cell proliferation that is involved in endocardial cushion morphogenesis. + rl + 2016-07-12T13:56:36Z + biological_process + GO:1905315 + cell proliferation involved in endocardial cushion morphogenesis + + + + + Any cell proliferation that is involved in endocardial cushion morphogenesis. + GOC:BHF + GOC:TermGenie + GOC:rl + GO_REF:0000060 + PMID:20652948 + + + + + + + + + + + + + + + + + + + The developmental process by which a superior endocardial cushion is generated and organized. + rl + 2016-07-12T14:08:35Z + dorsal endocardial cushion morphogenesis + biological_process + GO:1905316 + superior endocardial cushion morphogenesis + + + + + The developmental process by which a superior endocardial cushion is generated and organized. + GOC:BHF + GOC:TermGenie + GOC:rl + GO_REF:0000083 + PMID:17050629 + + + + + dorsal endocardial cushion morphogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + The developmental process by which an inferior endocardial cushion is generated and organized. + rl + 2016-07-12T14:14:56Z + ventral endocardial cushion morphogenesis + biological_process + GO:1905317 + inferior endocardial cushion morphogenesis + + + + + The developmental process by which an inferior endocardial cushion is generated and organized. + GOC:BHF + GOC:TermGenie + GOC:rl + GO_REF:0000083 + PMID:17050629 + + + + + ventral endocardial cushion morphogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + The process that gives rise to the tracheoesophageal septum. This process pertains to the initial formation of a structure from unspecified parts. + tb + 2016-07-21T18:18:57Z + esophagotracheal septum formation + biological_process + tracheoesophageal ridges formation + GO:1905327 + tracheoesophageal septum formation + + + + + The process that gives rise to the tracheoesophageal septum. This process pertains to the initial formation of a structure from unspecified parts. + GOC:TermGenie + GO_REF:0000081 + PMID:9731532 + + + + + esophagotracheal septum formation + GOC:TermGenie + + + + + tracheoesophageal ridges formation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of morphogenesis of an epithelium. + bhm + 2016-07-22T07:13:49Z + regulation of epithelium morphogenesis + biological_process + GO:1905330 + An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay). + regulation of morphogenesis of an epithelium + + + + + Any process that modulates the frequency, rate or extent of morphogenesis of an epithelium. + GOC:TermGenie + GOC:bhm + GO_REF:0000058 + PMID:25745997 + + + + + regulation of epithelium morphogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of morphogenesis of an epithelium. + bhm + 2016-07-22T07:13:57Z + down regulation of epithelium morphogenesis + down regulation of morphogenesis of an epithelium + down-regulation of epithelium morphogenesis + down-regulation of morphogenesis of an epithelium + downregulation of epithelium morphogenesis + downregulation of morphogenesis of an epithelium + negative regulation of epithelium morphogenesis + inhibition of epithelium morphogenesis + inhibition of morphogenesis of an epithelium + biological_process + GO:1905331 + An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay). + negative regulation of morphogenesis of an epithelium + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of morphogenesis of an epithelium. + GOC:TermGenie + GOC:bhm + GO_REF:0000058 + PMID:25745997 + + + + + down regulation of epithelium morphogenesis + GOC:TermGenie + + + + + down regulation of morphogenesis of an epithelium + GOC:TermGenie + + + + + down-regulation of epithelium morphogenesis + GOC:TermGenie + + + + + down-regulation of morphogenesis of an epithelium + GOC:TermGenie + + + + + downregulation of epithelium morphogenesis + GOC:TermGenie + + + + + downregulation of morphogenesis of an epithelium + GOC:TermGenie + + + + + negative regulation of epithelium morphogenesis + GOC:TermGenie + + + + + inhibition of epithelium morphogenesis + GOC:TermGenie + + + + + inhibition of morphogenesis of an epithelium + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of morphogenesis of an epithelium. + bhm + 2016-07-22T07:14:05Z + positive regulation of epithelium morphogenesis + up regulation of epithelium morphogenesis + up regulation of morphogenesis of an epithelium + up-regulation of epithelium morphogenesis + up-regulation of morphogenesis of an epithelium + upregulation of epithelium morphogenesis + upregulation of morphogenesis of an epithelium + activation of epithelium morphogenesis + activation of morphogenesis of an epithelium + biological_process + GO:1905332 + An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay). + positive regulation of morphogenesis of an epithelium + + + + + Any process that activates or increases the frequency, rate or extent of morphogenesis of an epithelium. + GOC:TermGenie + GOC:bhm + GO_REF:0000058 + PMID:25745997 + + + + + positive regulation of epithelium morphogenesis + GOC:TermGenie + + + + + up regulation of epithelium morphogenesis + GOC:TermGenie + + + + + up regulation of morphogenesis of an epithelium + GOC:TermGenie + + + + + up-regulation of epithelium morphogenesis + GOC:TermGenie + + + + + up-regulation of morphogenesis of an epithelium + GOC:TermGenie + + + + + upregulation of epithelium morphogenesis + GOC:TermGenie + + + + + upregulation of morphogenesis of an epithelium + GOC:TermGenie + + + + + activation of epithelium morphogenesis + GOC:TermGenie + + + + + activation of morphogenesis of an epithelium + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + The aggregation, arrangement and bonding together of a set of components to form a ciliary transition zone. + pr + 2016-08-04T14:49:43Z + cilial transition zone assembly + cilial transition zone formation + ciliary transition zone formation + cilium transition zone assembly + cilium transition zone formation + biological_process + GO:1905349 + ciliary transition zone assembly + + + + + The aggregation, arrangement and bonding together of a set of components to form a ciliary transition zone. + GOC:TermGenie + GOC:cilia + GO_REF:0000079 + PMID:21725307 + PMID:23644468 + PMID:24448408 + PMID:26595381 + PMID:26982032 + + + + + cilial transition zone assembly + GOC:TermGenie + + + + + cilial transition zone formation + GOC:TermGenie + + + + + ciliary transition zone formation + GOC:TermGenie + + + + + cilium transition zone assembly + GOC:TermGenie + + + + + cilium transition zone formation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any intracellular signal transduction that is involved in positive regulation of cell growth. + dph + 2016-09-07T18:15:01Z + intracellular signal transduction involved in up regulation of cell growth + intracellular signal transduction involved in up-regulation of cell growth + intracellular signal transduction involved in upregulation of cell growth + intracellular signaling chain involved in positive regulation of cell growth + intracellular signaling chain involved in up regulation of cell growth + intracellular signaling chain involved in up-regulation of cell growth + intracellular signaling chain involved in upregulation of cell growth + intracellular protein kinase cascade involved in activation of cell growth + intracellular protein kinase cascade involved in positive regulation of cell growth + intracellular protein kinase cascade involved in stimulation of cell growth + intracellular protein kinase cascade involved in up regulation of cell growth + intracellular protein kinase cascade involved in up-regulation of cell growth + intracellular protein kinase cascade involved in upregulation of cell growth + intracellular signal transduction involved in activation of cell growth + intracellular signal transduction involved in stimulation of cell growth + intracellular signal transduction pathway involved in activation of cell growth + intracellular signal transduction pathway involved in positive regulation of cell growth + intracellular signal transduction pathway involved in stimulation of cell growth + intracellular signal transduction pathway involved in up regulation of cell growth + intracellular signal transduction pathway involved in up-regulation of cell growth + intracellular signal transduction pathway involved in upregulation of cell growth + intracellular signaling chain involved in activation of cell growth + intracellular signaling chain involved in stimulation of cell growth + protein kinase cascade involved in activation of cell growth + protein kinase cascade involved in positive regulation of cell growth + protein kinase cascade involved in stimulation of cell growth + protein kinase cascade involved in up regulation of cell growth + protein kinase cascade involved in up-regulation of cell growth + protein kinase cascade involved in upregulation of cell growth + signal transmission via intracellular cascade involved in activation of cell growth + signal transmission via intracellular cascade involved in positive regulation of cell growth + signal transmission via intracellular cascade involved in stimulation of cell growth + signal transmission via intracellular cascade involved in up regulation of cell growth + signal transmission via intracellular cascade involved in up-regulation of cell growth + signal transmission via intracellular cascade involved in upregulation of cell growth + biological_process + intracellular signaling cascade involved in activation of cell growth + intracellular signaling cascade involved in positive regulation of cell growth + intracellular signaling cascade involved in stimulation of cell growth + intracellular signaling cascade involved in up regulation of cell growth + intracellular signaling cascade involved in up-regulation of cell growth + intracellular signaling cascade involved in upregulation of cell growth + intracellular signaling pathway involved in activation of cell growth + intracellular signaling pathway involved in positive regulation of cell growth + intracellular signaling pathway involved in stimulation of cell growth + intracellular signaling pathway involved in up regulation of cell growth + intracellular signaling pathway involved in up-regulation of cell growth + intracellular signaling pathway involved in upregulation of cell growth + signal transduction via intracellular signaling cascade involved in activation of cell growth + signal transduction via intracellular signaling cascade involved in positive regulation of cell growth + signal transduction via intracellular signaling cascade involved in stimulation of cell growth + signal transduction via intracellular signaling cascade involved in up regulation of cell growth + signal transduction via intracellular signaling cascade involved in up-regulation of cell growth + signal transduction via intracellular signaling cascade involved in upregulation of cell growth + GO:1905427 + intracellular signal transduction involved in positive regulation of cell growth + + + + + Any intracellular signal transduction that is involved in positive regulation of cell growth. + GOC:TermGenie + GOC:al + GOC:vw + GO_REF:0000060 + PMID:15917811 + + + + + intracellular signal transduction involved in up regulation of cell growth + GOC:TermGenie + + + + + intracellular signal transduction involved in up-regulation of cell growth + GOC:TermGenie + + + + + intracellular signal transduction involved in upregulation of cell growth + GOC:TermGenie + + + + + intracellular signaling chain involved in positive regulation of cell growth + GOC:TermGenie + + + + + intracellular signaling chain involved in up regulation of cell growth + GOC:TermGenie + + + + + intracellular signaling chain involved in up-regulation of cell growth + GOC:TermGenie + + + + + intracellular signaling chain involved in upregulation of cell growth + GOC:TermGenie + + + + + intracellular protein kinase cascade involved in activation of cell growth + GOC:TermGenie + + + + + intracellular protein kinase cascade involved in positive regulation of cell growth + GOC:TermGenie + + + + + intracellular protein kinase cascade involved in stimulation of cell growth + GOC:TermGenie + + + + + intracellular protein kinase cascade involved in up regulation of cell growth + GOC:TermGenie + + + + + intracellular protein kinase cascade involved in up-regulation of cell growth + GOC:TermGenie + + + + + intracellular protein kinase cascade involved in upregulation of cell growth + GOC:TermGenie + + + + + intracellular signal transduction involved in activation of cell growth + GOC:TermGenie + + + + + intracellular signal transduction involved in stimulation of cell growth + GOC:TermGenie + + + + + intracellular signal transduction pathway involved in activation of cell growth + GOC:TermGenie + + + + + intracellular signal transduction pathway involved in positive regulation of cell growth + GOC:TermGenie + + + + + intracellular signal transduction pathway involved in stimulation of cell growth + GOC:TermGenie + + + + + intracellular signal transduction pathway involved in up regulation of cell growth + GOC:TermGenie + + + + + intracellular signal transduction pathway involved in up-regulation of cell growth + GOC:TermGenie + + + + + intracellular signal transduction pathway involved in upregulation of cell growth + GOC:TermGenie + + + + + intracellular signaling chain involved in activation of cell growth + GOC:TermGenie + + + + + intracellular signaling chain involved in stimulation of cell growth + GOC:TermGenie + + + + + protein kinase cascade involved in activation of cell growth + GOC:TermGenie + + + + + protein kinase cascade involved in positive regulation of cell growth + GOC:TermGenie + + + + + protein kinase cascade involved in stimulation of cell growth + GOC:TermGenie + + + + + protein kinase cascade involved in up regulation of cell growth + GOC:TermGenie + + + + + protein kinase cascade involved in up-regulation of cell growth + GOC:TermGenie + + + + + protein kinase cascade involved in upregulation of cell growth + GOC:TermGenie + + + + + signal transmission via intracellular cascade involved in activation of cell growth + GOC:TermGenie + + + + + signal transmission via intracellular cascade involved in positive regulation of cell growth + GOC:TermGenie + + + + + signal transmission via intracellular cascade involved in stimulation of cell growth + GOC:TermGenie + + + + + signal transmission via intracellular cascade involved in up regulation of cell growth + GOC:TermGenie + + + + + signal transmission via intracellular cascade involved in up-regulation of cell growth + GOC:TermGenie + + + + + signal transmission via intracellular cascade involved in upregulation of cell growth + GOC:TermGenie + + + + + intracellular signaling cascade involved in activation of cell growth + GOC:TermGenie + + + + + intracellular signaling cascade involved in positive regulation of cell growth + GOC:TermGenie + + + + + intracellular signaling cascade involved in stimulation of cell growth + GOC:TermGenie + + + + + intracellular signaling cascade involved in up regulation of cell growth + GOC:TermGenie + + + + + intracellular signaling cascade involved in up-regulation of cell growth + GOC:TermGenie + + + + + intracellular signaling cascade involved in upregulation of cell growth + GOC:TermGenie + + + + + intracellular signaling pathway involved in activation of cell growth + GOC:TermGenie + + + + + intracellular signaling pathway involved in positive regulation of cell growth + GOC:TermGenie + + + + + intracellular signaling pathway involved in stimulation of cell growth + GOC:TermGenie + + + + + intracellular signaling pathway involved in up regulation of cell growth + GOC:TermGenie + + + + + intracellular signaling pathway involved in up-regulation of cell growth + GOC:TermGenie + + + + + intracellular signaling pathway involved in upregulation of cell growth + GOC:TermGenie + + + + + signal transduction via intracellular signaling cascade involved in activation of cell growth + GOC:TermGenie + + + + + signal transduction via intracellular signaling cascade involved in positive regulation of cell growth + GOC:TermGenie + + + + + signal transduction via intracellular signaling cascade involved in stimulation of cell growth + GOC:TermGenie + + + + + signal transduction via intracellular signaling cascade involved in up regulation of cell growth + GOC:TermGenie + + + + + signal transduction via intracellular signaling cascade involved in up-regulation of cell growth + GOC:TermGenie + + + + + signal transduction via intracellular signaling cascade involved in upregulation of cell growth + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of protein localization to membrane. + bc + 2016-09-21T16:20:03Z + regulation of protein localisation in membrane + regulation of protein localization in membrane + biological_process + GO:1905475 + regulation of protein localization to membrane + + + + + Any process that modulates the frequency, rate or extent of protein localization to membrane. + GOC:PARL + GOC:TermGenie + GOC:bc + GO_REF:0000058 + PMID:26911690 + + + + + regulation of protein localisation in membrane + GOC:TermGenie + + + + + regulation of protein localization in membrane + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to membrane. + bc + 2016-09-21T16:20:10Z + down regulation of protein localisation in membrane + down regulation of protein localization in membrane + down regulation of protein localization to membrane + down-regulation of protein localisation in membrane + down-regulation of protein localization in membrane + down-regulation of protein localization to membrane + downregulation of protein localisation in membrane + downregulation of protein localization in membrane + downregulation of protein localization to membrane + negative regulation of protein localisation in membrane + negative regulation of protein localization in membrane + inhibition of protein localisation in membrane + inhibition of protein localization in membrane + inhibition of protein localization to membrane + biological_process + GO:1905476 + negative regulation of protein localization to membrane + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to membrane. + GOC:PARL + GOC:TermGenie + GOC:bc + GO_REF:0000058 + PMID:26911690 + + + + + down regulation of protein localisation in membrane + GOC:TermGenie + + + + + down regulation of protein localization in membrane + GOC:TermGenie + + + + + down regulation of protein localization to membrane + GOC:TermGenie + + + + + down-regulation of protein localisation in membrane + GOC:TermGenie + + + + + down-regulation of protein localization in membrane + GOC:TermGenie + + + + + down-regulation of protein localization to membrane + GOC:TermGenie + + + + + downregulation of protein localisation in membrane + GOC:TermGenie + + + + + downregulation of protein localization in membrane + GOC:TermGenie + + + + + downregulation of protein localization to membrane + GOC:TermGenie + + + + + negative regulation of protein localisation in membrane + GOC:TermGenie + + + + + negative regulation of protein localization in membrane + GOC:TermGenie + + + + + inhibition of protein localisation in membrane + GOC:TermGenie + + + + + inhibition of protein localization in membrane + GOC:TermGenie + + + + + inhibition of protein localization to membrane + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of protein localization to membrane. + bc + 2016-09-21T16:20:18Z + positive regulation of protein localisation in membrane + positive regulation of protein localization in membrane + up regulation of protein localisation in membrane + up regulation of protein localization in membrane + up regulation of protein localization to membrane + up-regulation of protein localisation in membrane + up-regulation of protein localization in membrane + up-regulation of protein localization to membrane + upregulation of protein localisation in membrane + upregulation of protein localization in membrane + upregulation of protein localization to membrane + activation of protein localisation in membrane + activation of protein localization in membrane + activation of protein localization to membrane + biological_process + GO:1905477 + positive regulation of protein localization to membrane + + + + + Any process that activates or increases the frequency, rate or extent of protein localization to membrane. + GOC:PARL + GOC:TermGenie + GOC:bc + GO_REF:0000058 + PMID:26911690 + + + + + positive regulation of protein localisation in membrane + GOC:TermGenie + + + + + positive regulation of protein localization in membrane + GOC:TermGenie + + + + + up regulation of protein localisation in membrane + GOC:TermGenie + + + + + up regulation of protein localization in membrane + GOC:TermGenie + + + + + up regulation of protein localization to membrane + GOC:TermGenie + + + + + up-regulation of protein localisation in membrane + GOC:TermGenie + + + + + up-regulation of protein localization in membrane + GOC:TermGenie + + + + + up-regulation of protein localization to membrane + GOC:TermGenie + + + + + upregulation of protein localisation in membrane + GOC:TermGenie + + + + + upregulation of protein localization in membrane + GOC:TermGenie + + + + + upregulation of protein localization to membrane + GOC:TermGenie + + + + + activation of protein localisation in membrane + GOC:TermGenie + + + + + activation of protein localization in membrane + GOC:TermGenie + + + + + activation of protein localization to membrane + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of motor neuron migration. + hbye + 2016-09-23T12:49:54Z + biological_process + GO:1905483 + regulation of motor neuron migration + + + + + Any process that modulates the frequency, rate or extent of motor neuron migration. + GOC:TermGenie + GO_REF:0000058 + PMID:16516839 + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron migration. + hbye + 2016-09-23T12:50:11Z + down regulation of motor neuron migration + down-regulation of motor neuron migration + downregulation of motor neuron migration + inhibition of motor neuron migration + biological_process + GO:1905484 + negative regulation of motor neuron migration + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron migration. + GOC:TermGenie + GO_REF:0000058 + PMID:16516839 + + + + + down regulation of motor neuron migration + GOC:TermGenie + + + + + down-regulation of motor neuron migration + GOC:TermGenie + + + + + downregulation of motor neuron migration + GOC:TermGenie + + + + + inhibition of motor neuron migration + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of motor neuron migration. + hbye + 2016-09-23T12:50:19Z + up regulation of motor neuron migration + up-regulation of motor neuron migration + upregulation of motor neuron migration + activation of motor neuron migration + biological_process + GO:1905485 + positive regulation of motor neuron migration + + + + + Any process that activates or increases the frequency, rate or extent of motor neuron migration. + GOC:TermGenie + GO_REF:0000058 + PMID:16516839 + + + + + up regulation of motor neuron migration + GOC:TermGenie + + + + + up-regulation of motor neuron migration + GOC:TermGenie + + + + + upregulation of motor neuron migration + GOC:TermGenie + + + + + activation of motor neuron migration + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of branching morphogenesis of a nerve. + hbye + 2016-09-23T14:11:52Z + up regulation of branching morphogenesis of a nerve + up-regulation of branching morphogenesis of a nerve + upregulation of branching morphogenesis of a nerve + activation of branching morphogenesis of a nerve + biological_process + GO:1905492 + positive regulation of branching morphogenesis of a nerve + + + + + Any process that activates or increases the frequency, rate or extent of branching morphogenesis of a nerve. + GOC:TermGenie + GO_REF:0000058 + PMID:16516839 + + + + + up regulation of branching morphogenesis of a nerve + GOC:TermGenie + + + + + up-regulation of branching morphogenesis of a nerve + GOC:TermGenie + + + + + upregulation of branching morphogenesis of a nerve + GOC:TermGenie + + + + + activation of branching morphogenesis of a nerve + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of motile cilium assembly. + krc + 2016-09-27T18:27:47Z + biological_process + regulation of motile primary cilia assembly + regulation of motile primary cilia formation + regulation of motile primary cilium assembly + regulation of motile primary cilium formation + regulation of nodal cilium assembly + regulation of nodal cilium formation + GO:1905503 + regulation of motile cilium assembly + + + + + Any process that modulates the frequency, rate or extent of motile cilium assembly. + GOC:TermGenie + GOC:cilia + GOC:krc + GO_REF:0000058 + PMID:25294941 + + + + + regulation of motile primary cilia assembly + GOC:TermGenie + + + + + regulation of motile primary cilia formation + GOC:TermGenie + + + + + regulation of motile primary cilium formation + GOC:TermGenie + + + + + regulation of nodal cilium assembly + GOC:TermGenie + + + + + regulation of nodal cilium formation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of motile cilium assembly. + krc + 2016-09-27T18:27:55Z + inhibition of motile primary cilia assembly + inhibition of motile primary cilia formation + inhibition of motile primary cilium assembly + inhibition of motile primary cilium formation + biological_process + down regulation of motile primary cilia assembly + down regulation of motile primary cilia formation + down regulation of motile primary cilium assembly + down regulation of motile primary cilium formation + down regulation of nodal cilium assembly + down regulation of nodal cilium formation + down-regulation of motile primary cilia assembly + down-regulation of motile primary cilia formation + down-regulation of motile primary cilium assembly + down-regulation of motile primary cilium formation + down-regulation of nodal cilium assembly + down-regulation of nodal cilium formation + downregulation of motile primary cilia assembly + downregulation of motile primary cilia formation + downregulation of motile primary cilium assembly + downregulation of motile primary cilium formation + downregulation of nodal cilium assembly + downregulation of nodal cilium formation + inhibition of nodal cilium assembly + inhibition of nodal cilium formation + negative regulation of motile primary cilia assembly + negative regulation of motile primary cilia formation + negative regulation of motile primary cilium assembly + negative regulation of motile primary cilium formation + negative regulation of nodal cilium assembly + negative regulation of nodal cilium formation + GO:1905504 + negative regulation of motile cilium assembly + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of motile cilium assembly. + GOC:TermGenie + GOC:cilia + GOC:krc + GO_REF:0000058 + PMID:25294941 + + + + + inhibition of motile primary cilia assembly + GOC:TermGenie + + + + + inhibition of motile primary cilia formation + GOC:TermGenie + + + + + inhibition of motile primary cilium assembly + GOC:TermGenie + + + + + inhibition of motile primary cilium formation + GOC:TermGenie + + + + + down regulation of motile primary cilia assembly + GOC:TermGenie + + + + + down regulation of motile primary cilia formation + GOC:TermGenie + + + + + down regulation of motile primary cilium assembly + GOC:TermGenie + + + + + down regulation of motile primary cilium formation + GOC:TermGenie + + + + + down regulation of nodal cilium assembly + GOC:TermGenie + + + + + down regulation of nodal cilium formation + GOC:TermGenie + + + + + down-regulation of motile primary cilia assembly + GOC:TermGenie + + + + + down-regulation of motile primary cilia formation + GOC:TermGenie + + + + + down-regulation of motile primary cilium assembly + GOC:TermGenie + + + + + down-regulation of motile primary cilium formation + GOC:TermGenie + + + + + down-regulation of nodal cilium assembly + GOC:TermGenie + + + + + down-regulation of nodal cilium formation + GOC:TermGenie + + + + + downregulation of motile primary cilia assembly + GOC:TermGenie + + + + + downregulation of motile primary cilia formation + GOC:TermGenie + + + + + downregulation of motile primary cilium assembly + GOC:TermGenie + + + + + downregulation of motile primary cilium formation + GOC:TermGenie + + + + + downregulation of nodal cilium assembly + GOC:TermGenie + + + + + downregulation of nodal cilium formation + GOC:TermGenie + + + + + inhibition of nodal cilium assembly + GOC:TermGenie + + + + + inhibition of nodal cilium formation + GOC:TermGenie + + + + + negative regulation of motile primary cilia assembly + GOC:TermGenie + + + + + negative regulation of motile primary cilia formation + GOC:TermGenie + + + + + negative regulation of motile primary cilium formation + GOC:TermGenie + + + + + negative regulation of nodal cilium assembly + GOC:TermGenie + + + + + negative regulation of nodal cilium formation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of motile cilium assembly. + krc + 2016-09-27T18:28:03Z + activation of motile primary cilia assembly + activation of motile primary cilia formation + activation of motile primary cilium assembly + activation of motile primary cilium formation + biological_process + activation of nodal cilium assembly + activation of nodal cilium formation + positive regulation of motile primary cilia assembly + positive regulation of motile primary cilia formation + positive regulation of motile primary cilium assembly + positive regulation of motile primary cilium formation + positive regulation of nodal cilium assembly + positive regulation of nodal cilium formation + up regulation of motile primary cilia assembly + up regulation of motile primary cilia formation + up regulation of motile primary cilium assembly + up regulation of motile primary cilium formation + up regulation of nodal cilium assembly + up regulation of nodal cilium formation + up-regulation of motile primary cilia assembly + up-regulation of motile primary cilia formation + up-regulation of motile primary cilium assembly + up-regulation of motile primary cilium formation + up-regulation of nodal cilium assembly + up-regulation of nodal cilium formation + upregulation of motile primary cilia assembly + upregulation of motile primary cilia formation + upregulation of motile primary cilium assembly + upregulation of motile primary cilium formation + upregulation of nodal cilium assembly + upregulation of nodal cilium formation + GO:1905505 + positive regulation of motile cilium assembly + + + + + Any process that activates or increases the frequency, rate or extent of motile cilium assembly. + GOC:TermGenie + GOC:cilia + GOC:krc + GO_REF:0000058 + PMID:25294941 + + + + + activation of motile primary cilia assembly + GOC:TermGenie + + + + + activation of motile primary cilia formation + GOC:TermGenie + + + + + activation of motile primary cilium assembly + GOC:TermGenie + + + + + activation of motile primary cilium formation + GOC:TermGenie + + + + + activation of nodal cilium assembly + GOC:TermGenie + + + + + activation of nodal cilium formation + GOC:TermGenie + + + + + positive regulation of motile primary cilia assembly + GOC:TermGenie + + + + + positive regulation of motile primary cilia formation + GOC:TermGenie + + + + + positive regulation of motile primary cilium formation + GOC:TermGenie + + + + + positive regulation of nodal cilium assembly + GOC:TermGenie + + + + + positive regulation of nodal cilium formation + GOC:TermGenie + + + + + up regulation of motile primary cilia assembly + GOC:TermGenie + + + + + up regulation of motile primary cilia formation + GOC:TermGenie + + + + + up regulation of motile primary cilium assembly + GOC:TermGenie + + + + + up regulation of motile primary cilium formation + GOC:TermGenie + + + + + up regulation of nodal cilium assembly + GOC:TermGenie + + + + + up regulation of nodal cilium formation + GOC:TermGenie + + + + + up-regulation of motile primary cilia assembly + GOC:TermGenie + + + + + up-regulation of motile primary cilia formation + GOC:TermGenie + + + + + up-regulation of motile primary cilium assembly + GOC:TermGenie + + + + + up-regulation of motile primary cilium formation + GOC:TermGenie + + + + + up-regulation of nodal cilium assembly + GOC:TermGenie + + + + + up-regulation of nodal cilium formation + GOC:TermGenie + + + + + upregulation of motile primary cilia assembly + GOC:TermGenie + + + + + upregulation of motile primary cilia formation + GOC:TermGenie + + + + + upregulation of motile primary cilium assembly + GOC:TermGenie + + + + + upregulation of motile primary cilium formation + GOC:TermGenie + + + + + upregulation of nodal cilium assembly + GOC:TermGenie + + + + + upregulation of nodal cilium formation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + The aggregation, arrangement and bonding together of a set of components to form a non-motile cilium. + pr + 2016-09-30T11:55:15Z + GO:0035058 + non-motile cilium formation + nonmotile cilium assembly + nonmotile cilium formation + biological_process + immotile primary cilium assembly + nonmotile primary cilia assembly + nonmotile primary cilium assembly + sensory cilium assembly + sensory cilium biogenesis + GO:1905515 + non-motile cilium assembly + + + + + The aggregation, arrangement and bonding together of a set of components to form a non-motile cilium. + GOC:TermGenie + GOC:cilia + GOC:kmv + GO_REF:0000079 + PMID:14521833 + PMID:14521834 + + + + + non-motile cilium formation + GOC:TermGenie + + + + + nonmotile cilium assembly + GOC:TermGenie + + + + + nonmotile cilium formation + GOC:TermGenie + + + + + immotile primary cilium assembly + GOC:bf + + + + + nonmotile primary cilia assembly + GOC:bf + + + + + sensory cilium assembly + GOC:kmv + + + + + sensory cilium biogenesis + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of fertilization. + pr + 2016-09-30T14:32:32Z + positive regulation of syngamy + up regulation of fertilization + up regulation of syngamy + up-regulation of fertilization + up-regulation of syngamy + upregulation of fertilization + upregulation of syngamy + activation of fertilization + activation of syngamy + biological_process + GO:1905516 + positive regulation of fertilization + + + + + Any process that activates or increases the frequency, rate or extent of fertilization. + GOC:TermGenie + GOC:hbye + GO_REF:0000058 + PMID:27564576 + + + + + positive regulation of syngamy + GOC:TermGenie + + + + + up regulation of fertilization + GOC:TermGenie + + + + + up regulation of syngamy + GOC:TermGenie + + + + + up-regulation of fertilization + GOC:TermGenie + + + + + up-regulation of syngamy + GOC:TermGenie + + + + + upregulation of fertilization + GOC:TermGenie + + + + + upregulation of syngamy + GOC:TermGenie + + + + + activation of fertilization + GOC:TermGenie + + + + + activation of syngamy + GOC:TermGenie + + + + + + + + + + + + + + + + + + + The orderly movement of a macrophage from one site to another. + sl + 2016-09-30T22:17:45Z + biological_process + GO:1905517 + macrophage migration + + + + + The orderly movement of a macrophage from one site to another. + GOC:TermGenie + GO_REF:0000091 + PMID:25749876 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of macrophage migration. + sl + 2016-10-03T15:29:06Z + biological_process + GO:1905521 + regulation of macrophage migration + + + + + Any process that modulates the frequency, rate or extent of macrophage migration. + GOC:TermGenie + GO_REF:0000058 + PMID:25749876 + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of macrophage migration. + sl + 2016-10-03T15:29:14Z + down regulation of macrophage migration + down-regulation of macrophage migration + downregulation of macrophage migration + inhibition of macrophage migration + biological_process + GO:1905522 + negative regulation of macrophage migration + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of macrophage migration. + GOC:TermGenie + GO_REF:0000058 + PMID:25749876 + + + + + down regulation of macrophage migration + GOC:TermGenie + + + + + down-regulation of macrophage migration + GOC:TermGenie + + + + + downregulation of macrophage migration + GOC:TermGenie + + + + + inhibition of macrophage migration + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of macrophage migration. + sl + 2016-10-03T15:29:21Z + up regulation of macrophage migration + up-regulation of macrophage migration + upregulation of macrophage migration + activation of macrophage migration + biological_process + GO:1905523 + positive regulation of macrophage migration + + + + + Any process that activates or increases the frequency, rate or extent of macrophage migration. + GOC:TermGenie + GO_REF:0000058 + PMID:25749876 + + + + + up regulation of macrophage migration + GOC:TermGenie + + + + + up-regulation of macrophage migration + GOC:TermGenie + + + + + upregulation of macrophage migration + GOC:TermGenie + + + + + activation of macrophage migration + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of blood vessel branching. + nc + 2016-10-12T14:19:33Z + regulation of branching involved in blood vessel morphogenesis + biological_process + GO:1905553 + regulation of blood vessel branching + + + + + Any process that modulates the frequency, rate or extent of blood vessel branching. + GOC:BHF + GOC:BHF_telomere + GOC:TermGenie + GOC:nc + GO_REF:0000058 + PMID:23201774 + + + + + regulation of branching involved in blood vessel morphogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of blood vessel branching. + nc + 2016-10-12T14:19:41Z + down regulation of branching involved in blood vessel morphogenesis + down regulation of patterning of blood vessels + down-regulation of branching involved in blood vessel morphogenesis + down-regulation of patterning of blood vessels + downregulation of branching involved in blood vessel morphogenesis + downregulation of patterning of blood vessels + negative regulation of branching involved in blood vessel morphogenesis + inhibition of branching involved in blood vessel morphogenesis + inhibition of patterning of blood vessels + biological_process + GO:1905554 + negative regulation of vessel branching + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of blood vessel branching. + GOC:BHF + GOC:BHF_telomere + GOC:TermGenie + GOC:nc + GO_REF:0000058 + PMID:23201774 + + + + + down regulation of branching involved in blood vessel morphogenesis + GOC:TermGenie + + + + + down regulation of patterning of blood vessels + GOC:TermGenie + + + + + down-regulation of branching involved in blood vessel morphogenesis + GOC:TermGenie + + + + + down-regulation of patterning of blood vessels + GOC:TermGenie + + + + + downregulation of branching involved in blood vessel morphogenesis + GOC:TermGenie + + + + + downregulation of patterning of blood vessels + GOC:TermGenie + + + + + negative regulation of branching involved in blood vessel morphogenesis + GOC:TermGenie + + + + + inhibition of branching involved in blood vessel morphogenesis + GOC:TermGenie + + + + + inhibition of patterning of blood vessels + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of blood vessel branching. + nc + 2016-10-12T14:19:49Z + positive regulation of branching involved in blood vessel morphogenesis + up regulation of branching involved in blood vessel morphogenesis + up regulation of patterning of blood vessels + up-regulation of branching involved in blood vessel morphogenesis + up-regulation of patterning of blood vessels + upregulation of branching involved in blood vessel morphogenesis + upregulation of patterning of blood vessels + activation of branching involved in blood vessel morphogenesis + activation of patterning of blood vessels + biological_process + GO:1905555 + positive regulation of blood vessel branching + + + + + Any process that activates or increases the frequency, rate or extent of blood vessel branching. + GOC:BHF + GOC:BHF_telomere + GOC:TermGenie + GOC:nc + GO_REF:0000058 + PMID:23201774 + + + + + positive regulation of branching involved in blood vessel morphogenesis + GOC:TermGenie + + + + + up regulation of branching involved in blood vessel morphogenesis + GOC:TermGenie + + + + + up regulation of patterning of blood vessels + GOC:TermGenie + + + + + up-regulation of branching involved in blood vessel morphogenesis + GOC:TermGenie + + + + + up-regulation of patterning of blood vessels + GOC:TermGenie + + + + + upregulation of branching involved in blood vessel morphogenesis + GOC:TermGenie + + + + + upregulation of patterning of blood vessels + GOC:TermGenie + + + + + activation of branching involved in blood vessel morphogenesis + GOC:TermGenie + + + + + activation of patterning of blood vessels + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of vascular endothelial cell proliferation. + nc + 2016-10-17T09:24:17Z + biological_process + GO:1905562 + regulation of vascular endothelial cell proliferation + + + + + Any process that modulates the frequency, rate or extent of vascular endothelial cell proliferation. + GOC:BHF + GOC:BHF_telomere + GOC:TermGenie + GOC:nc + GO_REF:0000058 + PMID:23201774 + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial cell proliferation. + nc + 2016-10-17T09:24:26Z + down regulation of vascular endothelial cell proliferation + down-regulation of vascular endothelial cell proliferation + downregulation of vascular endothelial cell proliferation + inhibition of vascular endothelial cell proliferation + biological_process + GO:1905563 + negative regulation of vascular endothelial cell proliferation + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial cell proliferation. + GOC:BHF + GOC:BHF_telomere + GOC:TermGenie + GOC:nc + GO_REF:0000058 + PMID:23201774 + + + + + down regulation of vascular endothelial cell proliferation + GOC:TermGenie + + + + + down-regulation of vascular endothelial cell proliferation + GOC:TermGenie + + + + + downregulation of vascular endothelial cell proliferation + GOC:TermGenie + + + + + inhibition of vascular endothelial cell proliferation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of vascular endothelial cell proliferation. + nc + 2016-10-17T09:24:35Z + up regulation of vascular endothelial cell proliferation + up-regulation of vascular endothelial cell proliferation + upregulation of vascular endothelial cell proliferation + activation of vascular endothelial cell proliferation + biological_process + GO:1905564 + positive regulation of vascular endothelial cell proliferation + + + + + Any process that activates or increases the frequency, rate or extent of vascular endothelial cell proliferation. + GOC:BHF + GOC:BHF_telomere + GOC:TermGenie + GOC:nc + GO_REF:0000058 + PMID:23201774 + + + + + up regulation of vascular endothelial cell proliferation + GOC:TermGenie + + + + + up-regulation of vascular endothelial cell proliferation + GOC:TermGenie + + + + + upregulation of vascular endothelial cell proliferation + GOC:TermGenie + + + + + activation of vascular endothelial cell proliferation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of serotonin biosynthetic process. + pad + 2016-10-31T14:26:20Z + regulation of serotonin anabolism + regulation of serotonin biosynthesis + regulation of serotonin formation + regulation of serotonin synthesis + biological_process + GO:1905627 + regulation of serotonin biosynthetic process + + + + + Any process that modulates the frequency, rate or extent of serotonin biosynthetic process. + GOC:PARL + GOC:TermGenie + GOC:pad + GO_REF:0000058 + PMID:25642596 + + + + + regulation of serotonin anabolism + GOC:TermGenie + + + + + regulation of serotonin biosynthesis + GOC:TermGenie + + + + + regulation of serotonin formation + GOC:TermGenie + + + + + regulation of serotonin synthesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of serotonin biosynthetic process. + pad + 2016-10-31T14:26:28Z + down regulation of serotonin anabolism + down regulation of serotonin biosynthesis + down regulation of serotonin biosynthetic process + down regulation of serotonin formation + down regulation of serotonin synthesis + down-regulation of serotonin anabolism + down-regulation of serotonin biosynthesis + down-regulation of serotonin biosynthetic process + down-regulation of serotonin formation + down-regulation of serotonin synthesis + downregulation of serotonin anabolism + downregulation of serotonin biosynthesis + downregulation of serotonin biosynthetic process + downregulation of serotonin formation + downregulation of serotonin synthesis + negative regulation of serotonin anabolism + negative regulation of serotonin biosynthesis + negative regulation of serotonin formation + negative regulation of serotonin synthesis + inhibition of serotonin anabolism + inhibition of serotonin biosynthesis + inhibition of serotonin biosynthetic process + inhibition of serotonin formation + inhibition of serotonin synthesis + biological_process + GO:1905628 + negative regulation of serotonin biosynthetic process + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of serotonin biosynthetic process. + GOC:PARL + GOC:TermGenie + GOC:pad + GO_REF:0000058 + PMID:25642596 + + + + + down regulation of serotonin anabolism + GOC:TermGenie + + + + + down regulation of serotonin biosynthesis + GOC:TermGenie + + + + + down regulation of serotonin biosynthetic process + GOC:TermGenie + + + + + down regulation of serotonin formation + GOC:TermGenie + + + + + down regulation of serotonin synthesis + GOC:TermGenie + + + + + down-regulation of serotonin anabolism + GOC:TermGenie + + + + + down-regulation of serotonin biosynthesis + GOC:TermGenie + + + + + down-regulation of serotonin biosynthetic process + GOC:TermGenie + + + + + down-regulation of serotonin formation + GOC:TermGenie + + + + + down-regulation of serotonin synthesis + GOC:TermGenie + + + + + downregulation of serotonin anabolism + GOC:TermGenie + + + + + downregulation of serotonin biosynthesis + GOC:TermGenie + + + + + downregulation of serotonin biosynthetic process + GOC:TermGenie + + + + + downregulation of serotonin formation + GOC:TermGenie + + + + + downregulation of serotonin synthesis + GOC:TermGenie + + + + + negative regulation of serotonin anabolism + GOC:TermGenie + + + + + negative regulation of serotonin biosynthesis + GOC:TermGenie + + + + + negative regulation of serotonin formation + GOC:TermGenie + + + + + negative regulation of serotonin synthesis + GOC:TermGenie + + + + + inhibition of serotonin anabolism + GOC:TermGenie + + + + + inhibition of serotonin biosynthesis + GOC:TermGenie + + + + + inhibition of serotonin biosynthetic process + GOC:TermGenie + + + + + inhibition of serotonin formation + GOC:TermGenie + + + + + inhibition of serotonin synthesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of serotonin biosynthetic process. + pad + 2016-10-31T14:26:36Z + positive regulation of serotonin anabolism + positive regulation of serotonin biosynthesis + positive regulation of serotonin formation + positive regulation of serotonin synthesis + up regulation of serotonin anabolism + up regulation of serotonin biosynthesis + up regulation of serotonin biosynthetic process + up regulation of serotonin formation + up regulation of serotonin synthesis + up-regulation of serotonin anabolism + up-regulation of serotonin biosynthesis + up-regulation of serotonin biosynthetic process + up-regulation of serotonin formation + up-regulation of serotonin synthesis + upregulation of serotonin anabolism + upregulation of serotonin biosynthesis + upregulation of serotonin biosynthetic process + upregulation of serotonin formation + upregulation of serotonin synthesis + activation of serotonin anabolism + activation of serotonin biosynthesis + activation of serotonin biosynthetic process + activation of serotonin formation + activation of serotonin synthesis + biological_process + GO:1905629 + positive regulation of serotonin biosynthetic process + + + + + Any process that activates or increases the frequency, rate or extent of serotonin biosynthetic process. + GOC:PARL + GOC:TermGenie + GOC:pad + GO_REF:0000058 + PMID:25642596 + + + + + positive regulation of serotonin anabolism + GOC:TermGenie + + + + + positive regulation of serotonin biosynthesis + GOC:TermGenie + + + + + positive regulation of serotonin formation + GOC:TermGenie + + + + + positive regulation of serotonin synthesis + GOC:TermGenie + + + + + up regulation of serotonin anabolism + GOC:TermGenie + + + + + up regulation of serotonin biosynthesis + GOC:TermGenie + + + + + up regulation of serotonin biosynthetic process + GOC:TermGenie + + + + + up regulation of serotonin formation + GOC:TermGenie + + + + + up regulation of serotonin synthesis + GOC:TermGenie + + + + + up-regulation of serotonin anabolism + GOC:TermGenie + + + + + up-regulation of serotonin biosynthesis + GOC:TermGenie + + + + + up-regulation of serotonin biosynthetic process + GOC:TermGenie + + + + + up-regulation of serotonin formation + GOC:TermGenie + + + + + up-regulation of serotonin synthesis + GOC:TermGenie + + + + + upregulation of serotonin anabolism + GOC:TermGenie + + + + + upregulation of serotonin biosynthesis + GOC:TermGenie + + + + + upregulation of serotonin biosynthetic process + GOC:TermGenie + + + + + upregulation of serotonin formation + GOC:TermGenie + + + + + upregulation of serotonin synthesis + GOC:TermGenie + + + + + activation of serotonin anabolism + GOC:TermGenie + + + + + activation of serotonin biosynthesis + GOC:TermGenie + + + + + activation of serotonin biosynthetic process + GOC:TermGenie + + + + + activation of serotonin formation + GOC:TermGenie + + + + + activation of serotonin synthesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of artery morphogenesis. + rph + 2016-11-09T12:19:37Z + regulation of arterial morphogenesis + regulation of arteriogenesis + biological_process + GO:1905651 + regulation of artery morphogenesis + + + + + Any process that modulates the frequency, rate or extent of artery morphogenesis. + GOC:BHF + GOC:BHF_miRNA + GOC:TermGenie + GOC:rph + GO_REF:0000058 + PMID:27389411 + + + + + regulation of arterial morphogenesis + GOC:TermGenie + + + + + regulation of arteriogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of artery morphogenesis. + rph + 2016-11-09T12:19:53Z + down regulation of arterial morphogenesis + down regulation of arteriogenesis + down regulation of artery morphogenesis + down-regulation of arterial morphogenesis + down-regulation of arteriogenesis + down-regulation of artery morphogenesis + downregulation of arterial morphogenesis + downregulation of arteriogenesis + downregulation of artery morphogenesis + negative regulation of arterial morphogenesis + negative regulation of arteriogenesis + inhibition of arterial morphogenesis + inhibition of arteriogenesis + inhibition of artery morphogenesis + biological_process + GO:1905652 + negative regulation of artery morphogenesis + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of artery morphogenesis. + GOC:BHF + GOC:BHF_miRNA + GOC:TermGenie + GOC:rph + GO_REF:0000058 + PMID:27389411 + + + + + down regulation of arterial morphogenesis + GOC:TermGenie + + + + + down regulation of arteriogenesis + GOC:TermGenie + + + + + down regulation of artery morphogenesis + GOC:TermGenie + + + + + down-regulation of arterial morphogenesis + GOC:TermGenie + + + + + down-regulation of arteriogenesis + GOC:TermGenie + + + + + down-regulation of artery morphogenesis + GOC:TermGenie + + + + + downregulation of arterial morphogenesis + GOC:TermGenie + + + + + downregulation of arteriogenesis + GOC:TermGenie + + + + + downregulation of artery morphogenesis + GOC:TermGenie + + + + + negative regulation of arterial morphogenesis + GOC:TermGenie + + + + + negative regulation of arteriogenesis + GOC:TermGenie + + + + + inhibition of arterial morphogenesis + GOC:TermGenie + + + + + inhibition of arteriogenesis + GOC:TermGenie + + + + + inhibition of artery morphogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of artery morphogenesis. + rph + 2016-11-09T12:20:01Z + positive regulation of arterial morphogenesis + positive regulation of arteriogenesis + up regulation of arterial morphogenesis + up regulation of arteriogenesis + up regulation of artery morphogenesis + up-regulation of arterial morphogenesis + up-regulation of arteriogenesis + up-regulation of artery morphogenesis + upregulation of arterial morphogenesis + upregulation of arteriogenesis + upregulation of artery morphogenesis + activation of arterial morphogenesis + activation of arteriogenesis + activation of artery morphogenesis + biological_process + GO:1905653 + positive regulation of artery morphogenesis + + + + + Any process that activates or increases the frequency, rate or extent of artery morphogenesis. + GOC:BHF + GOC:BHF_miRNA + GOC:TermGenie + GOC:rph + GO_REF:0000058 + PMID:27389411 + + + + + positive regulation of arterial morphogenesis + GOC:TermGenie + + + + + positive regulation of arteriogenesis + GOC:TermGenie + + + + + up regulation of arterial morphogenesis + GOC:TermGenie + + + + + up regulation of arteriogenesis + GOC:TermGenie + + + + + up regulation of artery morphogenesis + GOC:TermGenie + + + + + up-regulation of arterial morphogenesis + GOC:TermGenie + + + + + up-regulation of arteriogenesis + GOC:TermGenie + + + + + up-regulation of artery morphogenesis + GOC:TermGenie + + + + + upregulation of arterial morphogenesis + GOC:TermGenie + + + + + upregulation of arteriogenesis + GOC:TermGenie + + + + + upregulation of artery morphogenesis + GOC:TermGenie + + + + + activation of arterial morphogenesis + GOC:TermGenie + + + + + activation of arteriogenesis + GOC:TermGenie + + + + + activation of artery morphogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any microtubule bundle that is part of a cytoplasm. + mah + 2016-11-24T16:52:02Z + microtubule bundle of cytoplasm + microtubule fascicle of cytoplasm + cellular_component + GO:1905720 + cytoplasmic microtubule bundle + + + + + Any microtubule bundle that is part of a cytoplasm. + GOC:TermGenie + GO_REF:0000064 + PMID:11007487 + PMID:26124291 + + + + + microtubule bundle of cytoplasm + GOC:TermGenie + + + + + microtubule fascicle of cytoplasm + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of saliva secretion. + pga + 2016-12-09T10:24:00Z + down regulation of saliva secretion + down regulation of salivation + down-regulation of saliva secretion + down-regulation of salivation + downregulation of saliva secretion + downregulation of salivation + negative regulation of salivation + inhibition of saliva secretion + inhibition of salivation + biological_process + GO:1905747 + negative regulation of saliva secretion + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of saliva secretion. + GOC:TermGenie + GO_REF:0000058 + PMID:23419067 + + + + + down regulation of saliva secretion + GOC:TermGenie + + + + + down regulation of salivation + GOC:TermGenie + + + + + down-regulation of saliva secretion + GOC:TermGenie + + + + + down-regulation of salivation + GOC:TermGenie + + + + + downregulation of saliva secretion + GOC:TermGenie + + + + + downregulation of salivation + GOC:TermGenie + + + + + negative regulation of salivation + GOC:TermGenie + + + + + inhibition of saliva secretion + GOC:TermGenie + + + + + inhibition of salivation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + The developmental process by which a hard palate is generated and organized. + pga + 2016-12-09T12:22:24Z + palatum durum morphogenesis + biological_process + GO:1905748 + hard palate morphogenesis + + + + + The developmental process by which a hard palate is generated and organized. + GOC:TermGenie + GO_REF:0000083 + PMID:23419067 + + + + + palatum durum morphogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + A process in which a protein is transported to, or maintained in, a location within a cytoplasmic microtubule. + mah + 2016-12-12T15:31:07Z + protein localisation to cytoplasmic microtubule + biological_process + GO:1905755 + protein localization to cytoplasmic microtubule + + + + + A process in which a protein is transported to, or maintained in, a location within a cytoplasmic microtubule. + GOC:TermGenie + GO_REF:0000087 + PMID:15177031 + + + + + protein localisation to cytoplasmic microtubule + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of mesodermal cell differentiation. + rph + 2016-12-21T12:44:13Z + regulation of mesoderm cell differentiation + biological_process + GO:1905770 + regulation of mesodermal cell differentiation + + + + + Any process that modulates the frequency, rate or extent of mesodermal cell differentiation. + GOC:BHF + GOC:BHF_miRNA + GOC:TermGenie + GOC:rph + GO_REF:0000058 + PMID:23765923 + + + + + regulation of mesoderm cell differentiation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of mesodermal cell differentiation. + rph + 2016-12-21T12:44:23Z + down regulation of mesoderm cell differentiation + down regulation of mesodermal cell differentiation + down-regulation of mesoderm cell differentiation + down-regulation of mesodermal cell differentiation + downregulation of mesoderm cell differentiation + downregulation of mesodermal cell differentiation + negative regulation of mesoderm cell differentiation + inhibition of mesoderm cell differentiation + inhibition of mesodermal cell differentiation + biological_process + GO:1905771 + negative regulation of mesodermal cell differentiation + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of mesodermal cell differentiation. + GOC:BHF + GOC:BHF_miRNA + GOC:TermGenie + GOC:rph + GO_REF:0000058 + PMID:23765923 + + + + + down regulation of mesoderm cell differentiation + GOC:TermGenie + + + + + down regulation of mesodermal cell differentiation + GOC:TermGenie + + + + + down-regulation of mesoderm cell differentiation + GOC:TermGenie + + + + + down-regulation of mesodermal cell differentiation + GOC:TermGenie + + + + + downregulation of mesoderm cell differentiation + GOC:TermGenie + + + + + downregulation of mesodermal cell differentiation + GOC:TermGenie + + + + + negative regulation of mesoderm cell differentiation + GOC:TermGenie + + + + + inhibition of mesoderm cell differentiation + GOC:TermGenie + + + + + inhibition of mesodermal cell differentiation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of mesodermal cell differentiation. + rph + 2016-12-21T12:44:32Z + positive regulation of mesoderm cell differentiation + up regulation of mesoderm cell differentiation + up regulation of mesodermal cell differentiation + up-regulation of mesoderm cell differentiation + up-regulation of mesodermal cell differentiation + upregulation of mesoderm cell differentiation + upregulation of mesodermal cell differentiation + activation of mesoderm cell differentiation + activation of mesodermal cell differentiation + biological_process + GO:1905772 + positive regulation of mesodermal cell differentiation + + + + + Any process that activates or increases the frequency, rate or extent of mesodermal cell differentiation. + GOC:BHF + GOC:BHF_miRNA + GOC:TermGenie + GOC:rph + GO_REF:0000058 + PMID:23765923 + + + + + positive regulation of mesoderm cell differentiation + GOC:TermGenie + + + + + up regulation of mesoderm cell differentiation + GOC:TermGenie + + + + + up regulation of mesodermal cell differentiation + GOC:TermGenie + + + + + up-regulation of mesoderm cell differentiation + GOC:TermGenie + + + + + up-regulation of mesodermal cell differentiation + GOC:TermGenie + + + + + upregulation of mesoderm cell differentiation + GOC:TermGenie + + + + + upregulation of mesodermal cell differentiation + GOC:TermGenie + + + + + activation of mesoderm cell differentiation + GOC:TermGenie + + + + + activation of mesodermal cell differentiation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch. + hbye + 2017-01-09T15:11:04Z + regulation of perception of touch, detection of mechanical stimulus + regulation of perception of touch, sensory detection of mechanical stimulus + regulation of perception of touch, sensory transduction of mechanical stimulus + regulation of sensory detection of mechanical stimulus during perception of touch + regulation of sensory transduction of mechanical stimulus during perception of touch + regulation of tactition, sensory detection of mechanical stimulus + biological_process + GO:1905787 + regulation of detection of mechanical stimulus involved in sensory perception of touch + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch. + GOC:TermGenie + GO_REF:0000058 + PMID:8692859 + + + + + regulation of perception of touch, detection of mechanical stimulus + GOC:TermGenie + + + + + regulation of perception of touch, sensory detection of mechanical stimulus + GOC:TermGenie + + + + + regulation of perception of touch, sensory transduction of mechanical stimulus + GOC:TermGenie + + + + + regulation of sensory detection of mechanical stimulus during perception of touch + GOC:TermGenie + + + + + regulation of sensory transduction of mechanical stimulus during perception of touch + GOC:TermGenie + + + + + regulation of tactition, sensory detection of mechanical stimulus + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch. + hbye + 2017-01-09T15:11:14Z + down regulation of detection of mechanical stimulus involved in sensory perception of touch + down regulation of perception of touch, detection of mechanical stimulus + down regulation of perception of touch, sensory detection of mechanical stimulus + down regulation of perception of touch, sensory transduction of mechanical stimulus + down regulation of sensory detection of mechanical stimulus during perception of touch + down regulation of sensory transduction of mechanical stimulus during perception of touch + down regulation of tactition, sensory detection of mechanical stimulus + down-regulation of detection of mechanical stimulus involved in sensory perception of touch + down-regulation of perception of touch, detection of mechanical stimulus + down-regulation of perception of touch, sensory detection of mechanical stimulus + down-regulation of perception of touch, sensory transduction of mechanical stimulus + down-regulation of sensory detection of mechanical stimulus during perception of touch + down-regulation of sensory transduction of mechanical stimulus during perception of touch + down-regulation of tactition, sensory detection of mechanical stimulus + downregulation of detection of mechanical stimulus involved in sensory perception of touch + downregulation of perception of touch, detection of mechanical stimulus + downregulation of perception of touch, sensory detection of mechanical stimulus + downregulation of perception of touch, sensory transduction of mechanical stimulus + downregulation of sensory detection of mechanical stimulus during perception of touch + downregulation of sensory transduction of mechanical stimulus during perception of touch + downregulation of tactition, sensory detection of mechanical stimulus + negative regulation of perception of touch, detection of mechanical stimulus + negative regulation of perception of touch, sensory detection of mechanical stimulus + negative regulation of perception of touch, sensory transduction of mechanical stimulus + negative regulation of sensory detection of mechanical stimulus during perception of touch + negative regulation of sensory transduction of mechanical stimulus during perception of touch + negative regulation of tactition, sensory detection of mechanical stimulus + inhibition of detection of mechanical stimulus involved in sensory perception of touch + inhibition of perception of touch, detection of mechanical stimulus + inhibition of perception of touch, sensory detection of mechanical stimulus + inhibition of perception of touch, sensory transduction of mechanical stimulus + inhibition of sensory detection of mechanical stimulus during perception of touch + inhibition of sensory transduction of mechanical stimulus during perception of touch + inhibition of tactition, sensory detection of mechanical stimulus + biological_process + GO:1905788 + negative regulation of detection of mechanical stimulus involved in sensory perception of touch + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch. + GOC:TermGenie + GO_REF:0000058 + PMID:8692859 + + + + + down regulation of detection of mechanical stimulus involved in sensory perception of touch + GOC:TermGenie + + + + + down regulation of perception of touch, detection of mechanical stimulus + GOC:TermGenie + + + + + down regulation of perception of touch, sensory detection of mechanical stimulus + GOC:TermGenie + + + + + down regulation of perception of touch, sensory transduction of mechanical stimulus + GOC:TermGenie + + + + + down regulation of sensory detection of mechanical stimulus during perception of touch + GOC:TermGenie + + + + + down regulation of sensory transduction of mechanical stimulus during perception of touch + GOC:TermGenie + + + + + down regulation of tactition, sensory detection of mechanical stimulus + GOC:TermGenie + + + + + down-regulation of detection of mechanical stimulus involved in sensory perception of touch + GOC:TermGenie + + + + + down-regulation of perception of touch, detection of mechanical stimulus + GOC:TermGenie + + + + + down-regulation of perception of touch, sensory detection of mechanical stimulus + GOC:TermGenie + + + + + down-regulation of perception of touch, sensory transduction of mechanical stimulus + GOC:TermGenie + + + + + down-regulation of sensory detection of mechanical stimulus during perception of touch + GOC:TermGenie + + + + + down-regulation of sensory transduction of mechanical stimulus during perception of touch + GOC:TermGenie + + + + + down-regulation of tactition, sensory detection of mechanical stimulus + GOC:TermGenie + + + + + downregulation of detection of mechanical stimulus involved in sensory perception of touch + GOC:TermGenie + + + + + downregulation of perception of touch, detection of mechanical stimulus + GOC:TermGenie + + + + + downregulation of perception of touch, sensory detection of mechanical stimulus + GOC:TermGenie + + + + + downregulation of perception of touch, sensory transduction of mechanical stimulus + GOC:TermGenie + + + + + downregulation of sensory detection of mechanical stimulus during perception of touch + GOC:TermGenie + + + + + downregulation of sensory transduction of mechanical stimulus during perception of touch + GOC:TermGenie + + + + + downregulation of tactition, sensory detection of mechanical stimulus + GOC:TermGenie + + + + + negative regulation of perception of touch, detection of mechanical stimulus + GOC:TermGenie + + + + + negative regulation of perception of touch, sensory detection of mechanical stimulus + GOC:TermGenie + + + + + negative regulation of perception of touch, sensory transduction of mechanical stimulus + GOC:TermGenie + + + + + negative regulation of sensory detection of mechanical stimulus during perception of touch + GOC:TermGenie + + + + + negative regulation of sensory transduction of mechanical stimulus during perception of touch + GOC:TermGenie + + + + + negative regulation of tactition, sensory detection of mechanical stimulus + GOC:TermGenie + + + + + inhibition of detection of mechanical stimulus involved in sensory perception of touch + GOC:TermGenie + + + + + inhibition of perception of touch, detection of mechanical stimulus + GOC:TermGenie + + + + + inhibition of perception of touch, sensory detection of mechanical stimulus + GOC:TermGenie + + + + + inhibition of perception of touch, sensory transduction of mechanical stimulus + GOC:TermGenie + + + + + inhibition of sensory detection of mechanical stimulus during perception of touch + GOC:TermGenie + + + + + inhibition of sensory transduction of mechanical stimulus during perception of touch + GOC:TermGenie + + + + + inhibition of tactition, sensory detection of mechanical stimulus + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch. + hbye + 2017-01-09T15:11:23Z + positive regulation of perception of touch, detection of mechanical stimulus + positive regulation of perception of touch, sensory detection of mechanical stimulus + positive regulation of perception of touch, sensory transduction of mechanical stimulus + positive regulation of sensory detection of mechanical stimulus during perception of touch + positive regulation of sensory transduction of mechanical stimulus during perception of touch + positive regulation of tactition, sensory detection of mechanical stimulus + up regulation of detection of mechanical stimulus involved in sensory perception of touch + up regulation of perception of touch, detection of mechanical stimulus + up regulation of perception of touch, sensory detection of mechanical stimulus + up regulation of perception of touch, sensory transduction of mechanical stimulus + up regulation of sensory detection of mechanical stimulus during perception of touch + up regulation of sensory transduction of mechanical stimulus during perception of touch + up regulation of tactition, sensory detection of mechanical stimulus + up-regulation of detection of mechanical stimulus involved in sensory perception of touch + up-regulation of perception of touch, detection of mechanical stimulus + up-regulation of perception of touch, sensory detection of mechanical stimulus + up-regulation of perception of touch, sensory transduction of mechanical stimulus + up-regulation of sensory detection of mechanical stimulus during perception of touch + up-regulation of sensory transduction of mechanical stimulus during perception of touch + up-regulation of tactition, sensory detection of mechanical stimulus + upregulation of detection of mechanical stimulus involved in sensory perception of touch + upregulation of perception of touch, detection of mechanical stimulus + upregulation of perception of touch, sensory detection of mechanical stimulus + upregulation of perception of touch, sensory transduction of mechanical stimulus + upregulation of sensory detection of mechanical stimulus during perception of touch + upregulation of sensory transduction of mechanical stimulus during perception of touch + upregulation of tactition, sensory detection of mechanical stimulus + activation of detection of mechanical stimulus involved in sensory perception of touch + activation of perception of touch, detection of mechanical stimulus + activation of perception of touch, sensory detection of mechanical stimulus + activation of perception of touch, sensory transduction of mechanical stimulus + activation of sensory detection of mechanical stimulus during perception of touch + activation of sensory transduction of mechanical stimulus during perception of touch + activation of tactition, sensory detection of mechanical stimulus + biological_process + GO:1905789 + positive regulation of detection of mechanical stimulus involved in sensory perception of touch + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that activates or increases the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch. + GOC:TermGenie + GO_REF:0000058 + PMID:8692859 + + + + + positive regulation of perception of touch, detection of mechanical stimulus + GOC:TermGenie + + + + + positive regulation of perception of touch, sensory detection of mechanical stimulus + GOC:TermGenie + + + + + positive regulation of perception of touch, sensory transduction of mechanical stimulus + GOC:TermGenie + + + + + positive regulation of sensory detection of mechanical stimulus during perception of touch + GOC:TermGenie + + + + + positive regulation of sensory transduction of mechanical stimulus during perception of touch + GOC:TermGenie + + + + + positive regulation of tactition, sensory detection of mechanical stimulus + GOC:TermGenie + + + + + up regulation of detection of mechanical stimulus involved in sensory perception of touch + GOC:TermGenie + + + + + up regulation of perception of touch, detection of mechanical stimulus + GOC:TermGenie + + + + + up regulation of perception of touch, sensory detection of mechanical stimulus + GOC:TermGenie + + + + + up regulation of perception of touch, sensory transduction of mechanical stimulus + GOC:TermGenie + + + + + up regulation of sensory detection of mechanical stimulus during perception of touch + GOC:TermGenie + + + + + up regulation of sensory transduction of mechanical stimulus during perception of touch + GOC:TermGenie + + + + + up regulation of tactition, sensory detection of mechanical stimulus + GOC:TermGenie + + + + + up-regulation of detection of mechanical stimulus involved in sensory perception of touch + GOC:TermGenie + + + + + up-regulation of perception of touch, detection of mechanical stimulus + GOC:TermGenie + + + + + up-regulation of perception of touch, sensory detection of mechanical stimulus + GOC:TermGenie + + + + + up-regulation of perception of touch, sensory transduction of mechanical stimulus + GOC:TermGenie + + + + + up-regulation of sensory detection of mechanical stimulus during perception of touch + GOC:TermGenie + + + + + up-regulation of sensory transduction of mechanical stimulus during perception of touch + GOC:TermGenie + + + + + up-regulation of tactition, sensory detection of mechanical stimulus + GOC:TermGenie + + + + + upregulation of detection of mechanical stimulus involved in sensory perception of touch + GOC:TermGenie + + + + + upregulation of perception of touch, detection of mechanical stimulus + GOC:TermGenie + + + + + upregulation of perception of touch, sensory detection of mechanical stimulus + GOC:TermGenie + + + + + upregulation of perception of touch, sensory transduction of mechanical stimulus + GOC:TermGenie + + + + + upregulation of sensory detection of mechanical stimulus during perception of touch + GOC:TermGenie + + + + + upregulation of sensory transduction of mechanical stimulus during perception of touch + GOC:TermGenie + + + + + upregulation of tactition, sensory detection of mechanical stimulus + GOC:TermGenie + + + + + activation of detection of mechanical stimulus involved in sensory perception of touch + GOC:TermGenie + + + + + activation of perception of touch, detection of mechanical stimulus + GOC:TermGenie + + + + + activation of perception of touch, sensory detection of mechanical stimulus + GOC:TermGenie + + + + + activation of perception of touch, sensory transduction of mechanical stimulus + GOC:TermGenie + + + + + activation of sensory detection of mechanical stimulus during perception of touch + GOC:TermGenie + + + + + activation of sensory transduction of mechanical stimulus during perception of touch + GOC:TermGenie + + + + + activation of tactition, sensory detection of mechanical stimulus + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of microtubule nucleation. + hbye + 2017-01-17T12:00:56Z + down regulation of microtubule nucleation + down-regulation of microtubule nucleation + downregulation of microtubule nucleation + inhibition of microtubule nucleation + biological_process + GO:1905833 + negative regulation of microtubule nucleation + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of microtubule nucleation. + GOC:TermGenie + GO_REF:0000058 + PMID:27689799 + + + + + down regulation of microtubule nucleation + GOC:TermGenie + + + + + down-regulation of microtubule nucleation + GOC:TermGenie + + + + + downregulation of microtubule nucleation + GOC:TermGenie + + + + + inhibition of microtubule nucleation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of an epididymis over time, from its formation to the mature structure. + sl + 2017-01-27T00:00:33Z + epididymus development + biological_process + GO:1905867 + epididymis development + + + + + The process whose specific outcome is the progression of an epididymis over time, from its formation to the mature structure. + GOC:TermGenie + GO_REF:0000094 + PMID:12388089 + + + + + epididymus development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of protein localization to cell leading edge. + sl + 2017-01-27T19:34:55Z + regulation of protein localisation in cell leading edge + regulation of protein localisation to cell leading edge + regulation of protein localization in cell leading edge + biological_process + GO:1905871 + regulation of protein localization to cell leading edge + + + + + Any process that modulates the frequency, rate or extent of protein localization to cell leading edge. + GOC:TermGenie + GO_REF:0000058 + PMID:26324884 + + + + + regulation of protein localisation in cell leading edge + GOC:TermGenie + + + + + regulation of protein localisation to cell leading edge + GOC:TermGenie + + + + + regulation of protein localization in cell leading edge + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell leading edge. + sl + 2017-01-27T19:35:04Z + down regulation of protein localisation in cell leading edge + down regulation of protein localisation to cell leading edge + down regulation of protein localization in cell leading edge + down regulation of protein localization to cell leading edge + down-regulation of protein localisation in cell leading edge + down-regulation of protein localisation to cell leading edge + down-regulation of protein localization in cell leading edge + down-regulation of protein localization to cell leading edge + downregulation of protein localisation in cell leading edge + downregulation of protein localisation to cell leading edge + downregulation of protein localization in cell leading edge + downregulation of protein localization to cell leading edge + negative regulation of protein localisation in cell leading edge + negative regulation of protein localisation to cell leading edge + negative regulation of protein localization in cell leading edge + inhibition of protein localisation in cell leading edge + inhibition of protein localisation to cell leading edge + inhibition of protein localization in cell leading edge + inhibition of protein localization to cell leading edge + biological_process + GO:1905872 + negative regulation of protein localization to cell leading edge + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell leading edge. + GOC:TermGenie + GO_REF:0000058 + PMID:26324884 + + + + + down regulation of protein localisation in cell leading edge + GOC:TermGenie + + + + + down regulation of protein localisation to cell leading edge + GOC:TermGenie + + + + + down regulation of protein localization in cell leading edge + GOC:TermGenie + + + + + down regulation of protein localization to cell leading edge + GOC:TermGenie + + + + + down-regulation of protein localisation in cell leading edge + GOC:TermGenie + + + + + down-regulation of protein localisation to cell leading edge + GOC:TermGenie + + + + + down-regulation of protein localization in cell leading edge + GOC:TermGenie + + + + + down-regulation of protein localization to cell leading edge + GOC:TermGenie + + + + + downregulation of protein localisation in cell leading edge + GOC:TermGenie + + + + + downregulation of protein localisation to cell leading edge + GOC:TermGenie + + + + + downregulation of protein localization in cell leading edge + GOC:TermGenie + + + + + downregulation of protein localization to cell leading edge + GOC:TermGenie + + + + + negative regulation of protein localisation in cell leading edge + GOC:TermGenie + + + + + negative regulation of protein localisation to cell leading edge + GOC:TermGenie + + + + + negative regulation of protein localization in cell leading edge + GOC:TermGenie + + + + + inhibition of protein localisation in cell leading edge + GOC:TermGenie + + + + + inhibition of protein localisation to cell leading edge + GOC:TermGenie + + + + + inhibition of protein localization in cell leading edge + GOC:TermGenie + + + + + inhibition of protein localization to cell leading edge + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of protein localization to cell leading edge. + sl + 2017-01-27T19:35:13Z + positive regulation of protein localisation in cell leading edge + positive regulation of protein localisation to cell leading edge + positive regulation of protein localization in cell leading edge + up regulation of protein localisation in cell leading edge + up regulation of protein localisation to cell leading edge + up regulation of protein localization in cell leading edge + up regulation of protein localization to cell leading edge + up-regulation of protein localisation in cell leading edge + up-regulation of protein localisation to cell leading edge + up-regulation of protein localization in cell leading edge + up-regulation of protein localization to cell leading edge + upregulation of protein localisation in cell leading edge + upregulation of protein localisation to cell leading edge + upregulation of protein localization in cell leading edge + upregulation of protein localization to cell leading edge + activation of protein localisation in cell leading edge + activation of protein localisation to cell leading edge + activation of protein localization in cell leading edge + activation of protein localization to cell leading edge + biological_process + GO:1905873 + positive regulation of protein localization to cell leading edge + + + + + Any process that activates or increases the frequency, rate or extent of protein localization to cell leading edge. + GOC:TermGenie + GO_REF:0000058 + PMID:26324884 + + + + + positive regulation of protein localisation in cell leading edge + GOC:TermGenie + + + + + positive regulation of protein localisation to cell leading edge + GOC:TermGenie + + + + + positive regulation of protein localization in cell leading edge + GOC:TermGenie + + + + + up regulation of protein localisation in cell leading edge + GOC:TermGenie + + + + + up regulation of protein localisation to cell leading edge + GOC:TermGenie + + + + + up regulation of protein localization in cell leading edge + GOC:TermGenie + + + + + up regulation of protein localization to cell leading edge + GOC:TermGenie + + + + + up-regulation of protein localisation in cell leading edge + GOC:TermGenie + + + + + up-regulation of protein localisation to cell leading edge + GOC:TermGenie + + + + + up-regulation of protein localization in cell leading edge + GOC:TermGenie + + + + + up-regulation of protein localization to cell leading edge + GOC:TermGenie + + + + + upregulation of protein localisation in cell leading edge + GOC:TermGenie + + + + + upregulation of protein localisation to cell leading edge + GOC:TermGenie + + + + + upregulation of protein localization in cell leading edge + GOC:TermGenie + + + + + upregulation of protein localization to cell leading edge + GOC:TermGenie + + + + + activation of protein localisation in cell leading edge + GOC:TermGenie + + + + + activation of protein localisation to cell leading edge + GOC:TermGenie + + + + + activation of protein localization in cell leading edge + GOC:TermGenie + + + + + activation of protein localization to cell leading edge + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of oogenesis. + hbye + 2017-01-31T09:31:05Z + regulation of ovum development + biological_process + GO:1905879 + regulation of oogenesis + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate or extent of oogenesis. + GOC:TermGenie + GO_REF:0000058 + PMID:26434723 + + + + + regulation of ovum development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of oogenesis. + hbye + 2017-01-31T09:31:15Z + down regulation of oogenesis + down regulation of ovum development + down-regulation of oogenesis + down-regulation of ovum development + downregulation of oogenesis + downregulation of ovum development + negative regulation of ovum development + inhibition of oogenesis + inhibition of ovum development + biological_process + GO:1905880 + negative regulation of oogenesis + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of oogenesis. + GOC:TermGenie + GO_REF:0000058 + PMID:26434723 + + + + + down regulation of oogenesis + GOC:TermGenie + + + + + down regulation of ovum development + GOC:TermGenie + + + + + down-regulation of oogenesis + GOC:TermGenie + + + + + down-regulation of ovum development + GOC:TermGenie + + + + + downregulation of oogenesis + GOC:TermGenie + + + + + downregulation of ovum development + GOC:TermGenie + + + + + negative regulation of ovum development + GOC:TermGenie + + + + + inhibition of oogenesis + GOC:TermGenie + + + + + inhibition of ovum development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of oogenesis. + hbye + 2017-01-31T09:31:23Z + positive regulation of ovum development + up regulation of oogenesis + up regulation of ovum development + up-regulation of oogenesis + up-regulation of ovum development + upregulation of oogenesis + upregulation of ovum development + activation of oogenesis + activation of ovum development + biological_process + GO:1905881 + positive regulation of oogenesis + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that activates or increases the frequency, rate or extent of oogenesis. + GOC:TermGenie + GO_REF:0000058 + PMID:26434723 + + + + + positive regulation of ovum development + GOC:TermGenie + + + + + up regulation of oogenesis + GOC:TermGenie + + + + + up regulation of ovum development + GOC:TermGenie + + + + + up-regulation of oogenesis + GOC:TermGenie + + + + + up-regulation of ovum development + GOC:TermGenie + + + + + upregulation of oogenesis + GOC:TermGenie + + + + + upregulation of ovum development + GOC:TermGenie + + + + + activation of oogenesis + GOC:TermGenie + + + + + activation of ovum development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of smooth muscle tissue development. + bhm + 2017-02-01T14:31:16Z + biological_process + GO:1905899 + regulation of smooth muscle tissue development + + + + + Any process that modulates the frequency, rate or extent of smooth muscle tissue development. + GOC:TermGenie + GOC:bhm + GO_REF:0000058 + PMID:14709716 + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle tissue development. + bhm + 2017-02-01T14:31:24Z + down regulation of smooth muscle tissue development + down-regulation of smooth muscle tissue development + downregulation of smooth muscle tissue development + inhibition of smooth muscle tissue development + biological_process + GO:1905900 + negative regulation of smooth muscle tissue development + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle tissue development. + GOC:TermGenie + GOC:bhm + GO_REF:0000058 + PMID:14709716 + + + + + down regulation of smooth muscle tissue development + GOC:TermGenie + + + + + down-regulation of smooth muscle tissue development + GOC:TermGenie + + + + + downregulation of smooth muscle tissue development + GOC:TermGenie + + + + + inhibition of smooth muscle tissue development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of smooth muscle tissue development. + bhm + 2017-02-01T14:31:33Z + up regulation of smooth muscle tissue development + up-regulation of smooth muscle tissue development + upregulation of smooth muscle tissue development + activation of smooth muscle tissue development + biological_process + GO:1905901 + positive regulation of smooth muscle tissue development + + + + + Any process that activates or increases the frequency, rate or extent of smooth muscle tissue development. + GOC:TermGenie + GOC:bhm + GO_REF:0000058 + PMID:14709716 + + + + + up regulation of smooth muscle tissue development + GOC:TermGenie + + + + + up-regulation of smooth muscle tissue development + GOC:TermGenie + + + + + upregulation of smooth muscle tissue development + GOC:TermGenie + + + + + activation of smooth muscle tissue development + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of mesoderm formation. + rph + 2017-02-03T12:28:20Z + biological_process + GO:1905902 + regulation of mesoderm formation + + + + + Any process that modulates the frequency, rate or extent of mesoderm formation. + GOC:BHF + GOC:BHF_miRNA + GOC:TermGenie + GOC:rph + GO_REF:0000058 + PMID:23939491 + + + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm formation. + rph + 2017-02-03T12:28:29Z + down regulation of mesoderm formation + down-regulation of mesoderm formation + downregulation of mesoderm formation + inhibition of mesoderm formation + biological_process + GO:1905903 + negative regulation of mesoderm formation + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm formation. + GOC:BHF + GOC:BHF_miRNA + GOC:TermGenie + GOC:rph + GO_REF:0000058 + PMID:23939491 + + + + + down regulation of mesoderm formation + GOC:TermGenie + + + + + down-regulation of mesoderm formation + GOC:TermGenie + + + + + downregulation of mesoderm formation + GOC:TermGenie + + + + + inhibition of mesoderm formation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of mesoderm formation. + rph + 2017-02-03T12:28:38Z + up regulation of mesoderm formation + up-regulation of mesoderm formation + upregulation of mesoderm formation + activation of mesoderm formation + biological_process + GO:1905904 + positive regulation of mesoderm formation + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that activates or increases the frequency, rate or extent of mesoderm formation. + GOC:BHF + GOC:BHF_miRNA + GOC:TermGenie + GOC:rph + GO_REF:0000058 + PMID:23939491 + + + + + up regulation of mesoderm formation + GOC:TermGenie + + + + + up-regulation of mesoderm formation + GOC:TermGenie + + + + + upregulation of mesoderm formation + GOC:TermGenie + + + + + activation of mesoderm formation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + The developmental process by which a pharyngeal gland is generated and organized. + rz + 2017-02-03T14:39:10Z + pharynx gland morphogenesis + biological_process + glandulae pharyngeae morphogenesis + GO:1905905 + pharyngeal gland morphogenesis + + + + + The developmental process by which a pharyngeal gland is generated and organized. + GOC:TermGenie + GO_REF:0000083 + PMID:21868609 + + + + + pharynx gland morphogenesis + GOC:TermGenie + + + + + glandulae pharyngeae morphogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of germ cell proliferation. + hbye + 2017-02-09T14:51:31Z + biological_process + GO:1905936 + regulation of germ cell proliferation + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate or extent of germ cell proliferation. + GOC:TermGenie + GO_REF:0000058 + PMID:15342467 + + + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of germ cell proliferation. + hbye + 2017-02-09T14:51:41Z + down regulation of germ cell proliferation + down-regulation of germ cell proliferation + downregulation of germ cell proliferation + inhibition of germ cell proliferation + biological_process + GO:1905937 + negative regulation of germ cell proliferation + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of germ cell proliferation. + GOC:TermGenie + GO_REF:0000058 + PMID:15342467 + + + + + down regulation of germ cell proliferation + GOC:TermGenie + + + + + down-regulation of germ cell proliferation + GOC:TermGenie + + + + + downregulation of germ cell proliferation + GOC:TermGenie + + + + + inhibition of germ cell proliferation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of germ cell proliferation. + hbye + 2017-02-09T14:51:51Z + up regulation of germ cell proliferation + up-regulation of germ cell proliferation + upregulation of germ cell proliferation + activation of germ cell proliferation + biological_process + GO:1905938 + positive regulation of germ cell proliferation + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that activates or increases the frequency, rate or extent of germ cell proliferation. + GOC:TermGenie + GO_REF:0000058 + PMID:15342467 + + + + + up regulation of germ cell proliferation + GOC:TermGenie + + + + + up-regulation of germ cell proliferation + GOC:TermGenie + + + + + upregulation of germ cell proliferation + GOC:TermGenie + + + + + activation of germ cell proliferation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of gonad development. + hbye + 2017-02-09T17:01:50Z + regulation of gonadogenesis + biological_process + GO:1905939 + regulation of gonad development + + + + + Any process that modulates the frequency, rate or extent of gonad development. + GOC:TermGenie + GO_REF:0000058 + PMID:15342467 + + + + + regulation of gonadogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of gonad development. + hbye + 2017-02-09T17:01:59Z + down regulation of gonad development + down regulation of gonadogenesis + down-regulation of gonad development + down-regulation of gonadogenesis + downregulation of gonad development + downregulation of gonadogenesis + negative regulation of gonadogenesis + inhibition of gonad development + inhibition of gonadogenesis + biological_process + GO:1905940 + negative regulation of gonad development + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of gonad development. + GOC:TermGenie + GO_REF:0000058 + PMID:15342467 + + + + + down regulation of gonad development + GOC:TermGenie + + + + + down regulation of gonadogenesis + GOC:TermGenie + + + + + down-regulation of gonad development + GOC:TermGenie + + + + + down-regulation of gonadogenesis + GOC:TermGenie + + + + + downregulation of gonad development + GOC:TermGenie + + + + + downregulation of gonadogenesis + GOC:TermGenie + + + + + negative regulation of gonadogenesis + GOC:TermGenie + + + + + inhibition of gonad development + GOC:TermGenie + + + + + inhibition of gonadogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of gonad development. + hbye + 2017-02-09T17:02:08Z + positive regulation of gonadogenesis + up regulation of gonad development + up regulation of gonadogenesis + up-regulation of gonad development + up-regulation of gonadogenesis + upregulation of gonad development + upregulation of gonadogenesis + activation of gonad development + activation of gonadogenesis + biological_process + GO:1905941 + positive regulation of gonad development + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that activates or increases the frequency, rate or extent of gonad development. + GOC:TermGenie + GO_REF:0000058 + PMID:15342467 + + + + + positive regulation of gonadogenesis + GOC:TermGenie + + + + + up regulation of gonad development + GOC:TermGenie + + + + + up regulation of gonadogenesis + GOC:TermGenie + + + + + up-regulation of gonad development + GOC:TermGenie + + + + + up-regulation of gonadogenesis + GOC:TermGenie + + + + + upregulation of gonad development + GOC:TermGenie + + + + + upregulation of gonadogenesis + GOC:TermGenie + + + + + activation of gonad development + GOC:TermGenie + + + + + activation of gonadogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of response to calcium ion. + bc + 2017-02-13T10:56:34Z + regulation of response to Ca2+ ion + biological_process + GO:1905945 + regulation of response to calcium ion + + + + + Any process that modulates the frequency, rate or extent of response to calcium ion. + GOC:TermGenie + GOC:aruk + GOC:bc + GO_REF:0000058 + PMID:11404397 + + + + + regulation of response to Ca2+ ion + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of response to calcium ion. + bc + 2017-02-13T10:56:41Z + down regulation of response to Ca2+ ion + down regulation of response to calcium ion + down-regulation of response to Ca2+ ion + down-regulation of response to calcium ion + downregulation of response to Ca2+ ion + downregulation of response to calcium ion + negative regulation of response to Ca2+ ion + inhibition of response to Ca2+ ion + inhibition of response to calcium ion + biological_process + GO:1905946 + negative regulation of response to calcium ion + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of response to calcium ion. + GOC:TermGenie + GOC:aruk + GOC:bc + GO_REF:0000058 + PMID:11404397 + + + + + down regulation of response to Ca2+ ion + GOC:TermGenie + + + + + down regulation of response to calcium ion + GOC:TermGenie + + + + + down-regulation of response to Ca2+ ion + GOC:TermGenie + + + + + down-regulation of response to calcium ion + GOC:TermGenie + + + + + downregulation of response to Ca2+ ion + GOC:TermGenie + + + + + downregulation of response to calcium ion + GOC:TermGenie + + + + + negative regulation of response to Ca2+ ion + GOC:TermGenie + + + + + inhibition of response to Ca2+ ion + GOC:TermGenie + + + + + inhibition of response to calcium ion + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of response to calcium ion. + bc + 2017-02-13T10:56:49Z + positive regulation of response to Ca2+ ion + up regulation of response to Ca2+ ion + up regulation of response to calcium ion + up-regulation of response to Ca2+ ion + up-regulation of response to calcium ion + upregulation of response to Ca2+ ion + upregulation of response to calcium ion + activation of response to Ca2+ ion + activation of response to calcium ion + biological_process + GO:1905947 + positive regulation of response to calcium ion + + + + + Any process that activates or increases the frequency, rate or extent of response to calcium ion. + GOC:TermGenie + GOC:aruk + GOC:bc + GO_REF:0000058 + PMID:11404397 + + + + + positive regulation of response to Ca2+ ion + GOC:TermGenie + + + + + up regulation of response to Ca2+ ion + GOC:TermGenie + + + + + up regulation of response to calcium ion + GOC:TermGenie + + + + + up-regulation of response to Ca2+ ion + GOC:TermGenie + + + + + up-regulation of response to calcium ion + GOC:TermGenie + + + + + upregulation of response to Ca2+ ion + GOC:TermGenie + + + + + upregulation of response to calcium ion + GOC:TermGenie + + + + + activation of response to Ca2+ ion + GOC:TermGenie + + + + + activation of response to calcium ion + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of lipid localization. + rz + 2017-02-21T12:12:22Z + regulation of lipid localisation + biological_process + GO:1905952 + regulation of lipid localization + + + + + Any process that modulates the frequency, rate or extent of lipid localization. + GOC:TermGenie + GO_REF:0000058 + PMID:17564681 + + + + + regulation of lipid localisation + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of lipid localization. + rz + 2017-02-21T12:12:41Z + down regulation of lipid localisation + down regulation of lipid localization + down-regulation of lipid localisation + down-regulation of lipid localization + downregulation of lipid localisation + downregulation of lipid localization + negative regulation of lipid localisation + inhibition of lipid localisation + inhibition of lipid localization + biological_process + GO:1905953 + negative regulation of lipid localization + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of lipid localization. + GOC:TermGenie + GO_REF:0000058 + PMID:17564681 + + + + + down regulation of lipid localisation + GOC:TermGenie + + + + + down regulation of lipid localization + GOC:TermGenie + + + + + down-regulation of lipid localisation + GOC:TermGenie + + + + + down-regulation of lipid localization + GOC:TermGenie + + + + + downregulation of lipid localisation + GOC:TermGenie + + + + + downregulation of lipid localization + GOC:TermGenie + + + + + negative regulation of lipid localisation + GOC:TermGenie + + + + + inhibition of lipid localisation + GOC:TermGenie + + + + + inhibition of lipid localization + GOC:TermGenie + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of lipid localization. + rz + 2017-02-21T12:12:49Z + positive regulation of lipid localisation + up regulation of lipid localisation + up regulation of lipid localization + up-regulation of lipid localisation + up-regulation of lipid localization + upregulation of lipid localisation + upregulation of lipid localization + activation of lipid localisation + activation of lipid localization + biological_process + GO:1905954 + positive regulation of lipid localization + + + + + Any process that activates or increases the frequency, rate or extent of lipid localization. + GOC:TermGenie + GO_REF:0000058 + PMID:17564681 + + + + + positive regulation of lipid localisation + GOC:TermGenie + + + + + up regulation of lipid localisation + GOC:TermGenie + + + + + up regulation of lipid localization + GOC:TermGenie + + + + + up-regulation of lipid localisation + GOC:TermGenie + + + + + up-regulation of lipid localization + GOC:TermGenie + + + + + upregulation of lipid localisation + GOC:TermGenie + + + + + upregulation of lipid localization + GOC:TermGenie + + + + + activation of lipid localisation + GOC:TermGenie + + + + + activation of lipid localization + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of endothelial tube morphogenesis. + rph + 2017-02-21T15:17:31Z + down regulation of endothelial tube morphogenesis + down-regulation of endothelial tube morphogenesis + downregulation of endothelial tube morphogenesis + inhibition of endothelial tube morphogenesis + biological_process + GO:1905955 + negative regulation of endothelial tube morphogenesis + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of endothelial tube morphogenesis. + GOC:BHF + GOC:BHF_miRNA + GOC:TermGenie + GOC:rph + GO_REF:0000058 + PMID:25961718 + + + + + down regulation of endothelial tube morphogenesis + GOC:TermGenie + + + + + down-regulation of endothelial tube morphogenesis + GOC:TermGenie + + + + + downregulation of endothelial tube morphogenesis + GOC:TermGenie + + + + + inhibition of endothelial tube morphogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of endothelial tube morphogenesis. + rph + 2017-02-21T15:17:39Z + up regulation of endothelial tube morphogenesis + up-regulation of endothelial tube morphogenesis + upregulation of endothelial tube morphogenesis + activation of endothelial tube morphogenesis + biological_process + GO:1905956 + positive regulation of endothelial tube morphogenesis + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that activates or increases the frequency, rate or extent of endothelial tube morphogenesis. + GOC:BHF + GOC:BHF_miRNA + GOC:TermGenie + GOC:rph + GO_REF:0000058 + PMID:25961718 + + + + + up regulation of endothelial tube morphogenesis + GOC:TermGenie + + + + + up-regulation of endothelial tube morphogenesis + GOC:TermGenie + + + + + upregulation of endothelial tube morphogenesis + GOC:TermGenie + + + + + activation of endothelial tube morphogenesis + GOC:TermGenie + + + + + + + + + + + + + + + + + + + A protein complex capable of catalyzing the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). + bhm + 2013-11-12T13:20:12Z + cellular_component + GO:1990234 + transferase complex + + + + + A protein complex capable of catalyzing the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). + GOC:bhm + PMID:16540464 + + + + + + + + + + + + + + + + + + + + + Binding to a steroid hormone. + pr + 2013-11-15T09:26:18Z + molecular_function + GO:1990239 + steroid hormone binding + + + + + Binding to a steroid hormone. + GOC:ln + + + + + + + + + + + + + + + + + + + + Binding to a keratin filament, an intermediate filament composed of acidic and basic keratins (types I and II), typically expressed in epithelial cells. + tb + 2013-12-13T22:05:25Z + molecular_function + GO:1990254 + keratin filament binding + + + + + Binding to a keratin filament, an intermediate filament composed of acidic and basic keratins (types I and II), typically expressed in epithelial cells. + GOC:krc + PMID:6170061 + + + + + + + + + + + + + + + + + + + + The reproductive developmental process whose specific outcome is the progression of the baculum over time, from its formation to the mature structure. + sl + 2014-05-01T23:59:13Z + os penis development + penile bone development + penis bone development + biological_process + GO:1990375 + baculum development + + + + + The reproductive developmental process whose specific outcome is the progression of the baculum over time, from its formation to the mature structure. + GOC:sl + PMID:21471296 + + + + + os penis development + GOC:sl + + + + + penile bone development + GOC:sl + + + + + penis bone development + GOC:sl + + + + + + + + + + + + + + + + + + + + The multiplication or reproduction of cholangiocytes, resulting in the expansion of the cholangiocyte population. A cholangiocyte is an epithelial cell that is part of the bile duct. Cholangiocytes contribute to bile secretion via net release of bicarbonate and water. + 2015-03-16T23:23:50Z + hepatoblast proliferation + biological_process + GO:1990705 + cholangiocyte proliferation + + + + + The multiplication or reproduction of cholangiocytes, resulting in the expansion of the cholangiocyte population. A cholangiocyte is an epithelial cell that is part of the bile duct. Cholangiocytes contribute to bile secretion via net release of bicarbonate and water. + PMID:24434010 + + + + + + + + + + + + + + + + + + + + The multiplication or reproduction of granulosa cells, resulting in the expansion of the granulosa cells population. A granulosa cell is a supporting cell for the developing female gamete in the ovary of mammals. They develop from the coelomic epithelial cells of the gonadal ridge. + sl + 2015-05-06T18:56:04Z + biological_process + GO:1990739 + granulosa cell proliferation + + + + + The multiplication or reproduction of granulosa cells, resulting in the expansion of the granulosa cells population. A granulosa cell is a supporting cell for the developing female gamete in the ovary of mammals. They develop from the coelomic epithelial cells of the gonadal ridge. + PMID:22383759 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry of the large intestine, exclusive of the rectum. The colon is that part of the large intestine that connects the small intestine to the rectum. + sl + 2015-06-10T18:29:21Z + biological_process + GO:1990765 + colon smooth muscle contraction + + + + + A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry of the large intestine, exclusive of the rectum. The colon is that part of the large intestine that connects the small intestine to the rectum. + PMID:24170253 + + + + + + + + + + + + + + + + + + + + The flow of blood through the gastric mucosa of an animal, enabling the transport of nutrients and the removal of waste products. + sl + 2015-06-10T20:11:09Z + stomach mucosal blood circulation + biological_process + GO:1990768 + gastric mucosal blood circulation + + + + + The flow of blood through the gastric mucosa of an animal, enabling the transport of nutrients and the removal of waste products. + PMID:10807413 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry in the intestine between the stomach and the large intestine. + sl + 2015-06-11T18:02:33Z + biological_process + GO:1990770 + small intestine smooth muscle contraction + + + + + A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry in the intestine between the stomach and the large intestine. + PMID:11991626 + + + + + + + + + + + + + + + + + + + + A process in which a protein is transported to, or maintained in, the cell periphery. + 2015-06-18T22:37:39Z + biological_process + GO:1990778 + protein localization to cell periphery + + + + + A process in which a protein is transported to, or maintained in, the cell periphery. + PMID:18216290 + + + + + + + + + + + + + + + + + + + + The process whose specific outcome is the progression of a dorsal root ganglion over time, from its formation to the mature structure. + sl + 2015-07-02T22:09:54Z + DRG development + biological_process + GO:1990791 + dorsal root ganglion development + + + + + The process whose specific outcome is the progression of a dorsal root ganglion over time, from its formation to the mature structure. + PMID:18583150 + + + + + + + + + The regulated production of heat in response to short term environmental changes, such as stress, diet or reduced temperature. + sl + 2015-08-31T18:19:49Z + biological_process + GO:1990845 + adaptive thermogenesis + + + + + The regulated production of heat in response to short term environmental changes, such as stress, diet or reduced temperature. + PMID:17260010 + PMID:20363363 + + + + + + + + + + + + + + + + + + + Any process in which the vacuole is transported to, and/or maintained in, a specific location within the cell. + https://github.com/geneontology/go-ontology/issues/22182 + mcc + 2015-09-10T08:16:02Z + maintenance of vacuolar localization + maintenance of vacuole localization + maintenance of vacuole location + maintenance of vacuolar location + biological_process + GO:1990849 + vacuolar localization + + + + + Any process in which the vacuole is transported to, and/or maintained in, a specific location within the cell. + PMID:26283797 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + The cytoplasm of an ovum. + + sl + 2015-12-10T21:40:16Z + cellular_component + GO:1990917 + ooplasm + + + + + The cytoplasm of an ovum. + PMID:19022436 + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of metanephric S-shaped body morphogenesis. + jl + 2010-07-30T02:14:33Z + biological_process + GO:2000004 + regulation of metanephric S-shaped body morphogenesis + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate or extent of metanephric S-shaped body morphogenesis. + GOC:mtg_kidney_jan10 + GOC:obol + GOC:yaf + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of metanephric S-shaped body morphogenesis. + jl + 2010-07-30T02:14:37Z + biological_process + GO:2000005 + negative regulation of metanephric S-shaped body morphogenesis + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of metanephric S-shaped body morphogenesis. + GOC:mtg_kidney_jan10 + GOC:obol + GOC:yaf + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of metanephric comma-shaped body morphogenesis. + jl + 2010-07-30T02:17:12Z + biological_process + GO:2000006 + regulation of metanephric comma-shaped body morphogenesis + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate or extent of metanephric comma-shaped body morphogenesis. + GOC:mtg_kidney_jan10 + GOC:obol + GOC:yaf + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of metanephric comma-shaped body morphogenesis. + jl + 2010-07-30T02:17:17Z + biological_process + GO:2000007 + negative regulation of metanephric comma-shaped body morphogenesis + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of metanephric comma-shaped body morphogenesis. + GOC:mtg_kidney_jan10 + GOC:obol + GOC:yaf + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of male gonad development. + jl + 2010-07-15T03:29:05Z + regulation of testicular development + regulation of testis development + biological_process + GO:2000018 + regulation of male gonad development + + + + + Any process that modulates the frequency, rate or extent of male gonad development. + GOC:obol + GOC:yaf + + + + + regulation of testicular development + GOC:obol + + + + + regulation of testis development + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of male gonad development. + jl + 2010-07-15T03:29:10Z + negative regulation of testicular development + negative regulation of testis development + biological_process + GO:2000019 + negative regulation of male gonad development + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of male gonad development. + GOC:obol + GOC:yaf + + + + + negative regulation of testicular development + GOC:obol + + + + + negative regulation of testis development + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of male gonad development. + jl + 2010-07-15T03:29:13Z + positive regulation of testicular development + positive regulation of testis development + biological_process + GO:2000020 + positive regulation of male gonad development + + + + + Any process that activates or increases the frequency, rate or extent of male gonad development. + GOC:obol + + + + + positive regulation of testicular development + GOC:obol + + + + + positive regulation of testis development + GOC:obol + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of multicellular organismal development. + tb + 2010-08-05T11:25:59Z + biological_process + GO:2000026 + regulation of multicellular organismal development + + + + + Any process that modulates the frequency, rate or extent of multicellular organismal development. + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of animal organ morphogenesis. + tb + 2010-08-05T11:26:27Z + biological_process + regulation of histogenesis and organogenesis + GO:2000027 + regulation of animal organ morphogenesis + + + + + Any process that modulates the frequency, rate or extent of animal organ morphogenesis. + GOC:obol + + + + + regulation of histogenesis and organogenesis + GOC:obol + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of stem cell division. + tb + 2010-08-05T11:34:53Z + regulation of stem cell renewal + biological_process + GO:2000035 + regulation of stem cell division + + + + + Any process that modulates the frequency, rate or extent of stem cell division. + GOC:obol + + + + + regulation of stem cell renewal + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of defense response to insect. + tb + 2010-08-23T09:30:00Z + regulation of physiological defense response to insect + biological_process + GO:2000068 + regulation of defense response to insect + + + + + Any process that modulates the frequency, rate or extent of defense response to insect. + GOC:obol + + + + + regulation of physiological defense response to insect + GOC:obol + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of response to water deprivation. + tb + 2010-08-23T11:32:32Z + regulation of response to dehydration + regulation of response to drought + regulation of response to thirst + biological_process + regulation of drought tolerance + GO:2000070 + regulation of response to water deprivation + + + + + Any process that modulates the frequency, rate or extent of response to water deprivation. + GOC:obol + + + + + regulation of response to dehydration + GOC:obol + + + + + regulation of response to drought + GOC:obol + + + + + regulation of response to thirst + GOC:obol + + + + + regulation of drought tolerance + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis. + dph + 2010-09-03T06:06:41Z + biological_process + regulation of mesonephric mesenchyme to epithelial transition + GO:2000084 + regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis + + + + + Any process that modulates the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis. + GOC:mtg_kidney_jan10 + + + + + regulation of mesonephric mesenchyme to epithelial transition + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis. + dph + 2010-09-03T06:08:21Z + biological_process + negative regulation of mesonephric mesenchyme to epithelial transition + GO:2000085 + negative regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis. + GOC:mtg_kidney_jan10 + + + + + negative regulation of mesonephric mesenchyme to epithelial transition + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis. + dph + 2010-09-03T06:08:24Z + biological_process + positive regulation of mesonephric mesenchyme to epithelial transition + GO:2000086 + positive regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis + + + + + Any process that activates or increases the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis. + GOC:mtg_kidney_jan10 + + + + + positive regulation of mesonephric mesenchyme to epithelial transition + GOC:obol + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of mesonephric glomerulus development. + dph + 2010-09-03T06:09:19Z + biological_process + GO:2000087 + regulation of mesonephric glomerulus development + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate or extent of mesonephric glomerulus development. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of mesonephric glomerulus development. + dph + 2010-09-03T06:09:22Z + biological_process + GO:2000088 + negative regulation of mesonephric glomerulus development + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of mesonephric glomerulus development. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of mesonephric glomerulus development. + dph + 2010-09-03T06:09:24Z + biological_process + GO:2000089 + positive regulation of mesonephric glomerulus development + + + + + Any process that activates or increases the frequency, rate or extent of mesonephric glomerulus development. + GOC:mtg_kidney_jan10 + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of cellular macromolecule biosynthetic process. + tb + 2010-09-15T08:55:45Z + regulation of cellular biopolymer biosynthetic process + regulation of cellular macromolecule anabolism + regulation of cellular macromolecule biosynthesis + regulation of cellular macromolecule formation + regulation of cellular macromolecule synthesis + biological_process + GO:2000112 + regulation of cellular macromolecule biosynthetic process + + + + + Any process that modulates the frequency, rate or extent of cellular macromolecule biosynthetic process. + GOC:obol + + + + + regulation of cellular biopolymer biosynthetic process + GOC:obol + + + + + regulation of cellular macromolecule anabolism + GOC:obol + + + + + regulation of cellular macromolecule biosynthesis + GOC:obol + + + + + regulation of cellular macromolecule formation + GOC:obol + + + + + regulation of cellular macromolecule synthesis + GOC:obol + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of cellular macromolecule biosynthetic process. + tb + 2010-09-15T08:55:48Z + negative regulation of cellular biopolymer biosynthetic process + negative regulation of cellular macromolecule anabolism + negative regulation of cellular macromolecule biosynthesis + negative regulation of cellular macromolecule formation + negative regulation of cellular macromolecule synthesis + biological_process + GO:2000113 + negative regulation of cellular macromolecule biosynthetic process + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of cellular macromolecule biosynthetic process. + GOC:obol + + + + + negative regulation of cellular biopolymer biosynthetic process + GOC:obol + + + + + negative regulation of cellular macromolecule anabolism + GOC:obol + + + + + negative regulation of cellular macromolecule biosynthesis + GOC:obol + + + + + negative regulation of cellular macromolecule formation + GOC:obol + + + + + negative regulation of cellular macromolecule synthesis + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of establishment of cell polarity. + dph + 2010-09-16T01:22:36Z + regulation of cell polarization + biological_process + regulation of bud site selection/establishment of cell polarity + GO:2000114 + regulation of establishment of cell polarity + + + + + Any process that modulates the frequency, rate or extent of establishment of cell polarity. + GOC:dph + + + + + regulation of cell polarization + GOC:obol + + + + + regulation of bud site selection/establishment of cell polarity + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of cell proliferation involved in heart morphogenesis. + dph + 2010-09-29T12:43:53Z + biological_process + GO:2000136 + regulation of cell proliferation involved in heart morphogenesis + + + + + Any process that modulates the frequency, rate or extent of cell proliferation involved in heart morphogenesis. + GOC:dph + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of cell proliferation involved in heart morphogenesis. + dph + 2010-09-29T12:43:55Z + biological_process + GO:2000137 + negative regulation of cell proliferation involved in heart morphogenesis + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of cell proliferation involved in heart morphogenesis. + GOC:dph + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of cell proliferation involved in heart morphogenesis. + dph + 2010-09-29T12:43:57Z + biological_process + GO:2000138 + positive regulation of cell proliferation involved in heart morphogenesis + + + + + Any process that activates or increases the frequency, rate or extent of cell proliferation involved in heart morphogenesis. + GOC:dph + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of cell motility. + mah + 2010-10-01T09:41:21Z + regulation of cell locomotion + regulation of movement of a cell + biological_process + regulation of cell movement + GO:2000145 + regulation of cell motility + + + + + Any process that modulates the frequency, rate or extent of cell motility. + GOC:mah + + + + + regulation of cell locomotion + GOC:obol + + + + + regulation of movement of a cell + GOC:obol + + + + + regulation of cell movement + GOC:obol + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of cell motility. + mah + 2010-10-01T09:41:26Z + negative regulation of cell locomotion + negative regulation of movement of a cell + biological_process + negative regulation of cell movement + GO:2000146 + negative regulation of cell motility + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of cell motility. + GOC:mah + + + + + negative regulation of cell locomotion + GOC:obol + + + + + negative regulation of movement of a cell + GOC:obol + + + + + negative regulation of cell movement + GOC:obol + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of cell motility. + mah + 2010-10-01T09:41:30Z + positive regulation of cell locomotion + positive regulation of movement of a cell + biological_process + positive regulation of cell movement + GO:2000147 + positive regulation of cell motility + + + + + Any process that activates or increases the frequency, rate or extent of cell motility. + GOC:mah + + + + + positive regulation of cell locomotion + GOC:obol + + + + + positive regulation of movement of a cell + GOC:obol + + + + + positive regulation of cell movement + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of cilium-dependent cell motility. + mah + 2010-10-04T12:41:05Z + biological_process + positive regulation of ciliary cell motility + GO:2000155 + positive regulation of cilium-dependent cell motility + + + + + Any process that activates or increases the frequency, rate or extent of cilium-dependent cell motility. + GOC:cilia + GOC:jl + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite development. + rl + 2010-10-07T10:53:15Z + biological_process + GO:2000171 + negative regulation of dendrite development + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite development. + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of branching morphogenesis of a nerve. + rl + 2010-10-07T12:07:54Z + biological_process + GO:2000172 + regulation of branching morphogenesis of a nerve + + + + + Any process that modulates the frequency, rate or extent of branching morphogenesis of a nerve. + GOC:BHF + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of branching morphogenesis of a nerve. + rl + 2010-10-07T12:07:56Z + biological_process + GO:2000173 + negative regulation of branching morphogenesis of a nerve + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of branching morphogenesis of a nerve. + GOC:BHF + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of neural precursor cell proliferation. + dph + 2010-10-13T12:40:41Z + biological_process + GO:2000177 + regulation of neural precursor cell proliferation + + + + + Any process that modulates the frequency, rate or extent of neural precursor cell proliferation. + GOC:dph + GOC:yaf + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of neural precursor cell proliferation. + dph + 2010-10-13T12:40:43Z + biological_process + GO:2000178 + negative regulation of neural precursor cell proliferation + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of neural precursor cell proliferation. + GOC:dph + GOC:yaf + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of neural precursor cell proliferation. + dph + 2010-10-13T12:40:45Z + biological_process + GO:2000179 + positive regulation of neural precursor cell proliferation + + + + + Any process that activates or increases the frequency, rate or extent of neural precursor cell proliferation. + GOC:dph + GOC:yaf + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis. + dph + 2010-10-13T12:46:31Z + biological_process + GO:2000181 + negative regulation of blood vessel morphogenesis + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis. + GOC:dph + GOC:yaf + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of progesterone biosynthetic process. + dph + 2010-10-14T07:36:06Z + regulation of progesterone anabolism + regulation of progesterone biosynthesis + regulation of progesterone formation + regulation of progesterone synthesis + biological_process + GO:2000182 + regulation of progesterone biosynthetic process + + + + + Any process that modulates the frequency, rate or extent of progesterone biosynthetic process. + GOC:dph + + + + + regulation of progesterone anabolism + GOC:obol + + + + + regulation of progesterone biosynthesis + GOC:obol + + + + + regulation of progesterone formation + GOC:obol + + + + + regulation of progesterone synthesis + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of progesterone biosynthetic process. + dph + 2010-10-14T07:36:10Z + negative regulation of progesterone anabolism + negative regulation of progesterone biosynthesis + negative regulation of progesterone formation + negative regulation of progesterone synthesis + biological_process + GO:2000183 + negative regulation of progesterone biosynthetic process + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of progesterone biosynthetic process. + GOC:dph + + + + + negative regulation of progesterone anabolism + GOC:obol + + + + + negative regulation of progesterone biosynthesis + GOC:obol + + + + + negative regulation of progesterone formation + GOC:obol + + + + + negative regulation of progesterone synthesis + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of progesterone biosynthetic process. + dph + 2010-10-14T07:36:14Z + positive regulation of progesterone anabolism + positive regulation of progesterone biosynthesis + positive regulation of progesterone formation + positive regulation of progesterone synthesis + biological_process + GO:2000184 + positive regulation of progesterone biosynthetic process + + + + + Any process that activates or increases the frequency, rate or extent of progesterone biosynthetic process. + GOC:dph + + + + + positive regulation of progesterone anabolism + GOC:obol + + + + + positive regulation of progesterone biosynthesis + GOC:obol + + + + + positive regulation of progesterone formation + GOC:obol + + + + + positive regulation of progesterone synthesis + GOC:obol + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of female gonad development. + yaf + 2010-10-19T10:45:34Z + regulation of ovarian development + regulation of ovary development + biological_process + GO:2000194 + regulation of female gonad development + + + + + Any process that modulates the frequency, rate or extent of female gonad development. + GOC:obol + + + + + regulation of ovarian development + GOC:obol + + + + + regulation of ovary development + GOC:obol + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of female gonad development. + yaf + 2010-10-19T10:45:38Z + negative regulation of ovarian development + negative regulation of ovary development + biological_process + GO:2000195 + negative regulation of female gonad development + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of female gonad development. + GOC:obol + + + + + negative regulation of ovarian development + GOC:obol + + + + + negative regulation of ovary development + GOC:obol + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of female gonad development. + yaf + 2010-10-19T10:45:41Z + positive regulation of ovarian development + positive regulation of ovary development + biological_process + GO:2000196 + positive regulation of female gonad development + + + + + Any process that activates or increases the frequency, rate or extent of female gonad development. + GOC:obol + + + + + positive regulation of ovarian development + GOC:obol + + + + + positive regulation of ovary development + GOC:obol + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of glutamate metabolic process. + mah + 2010-11-03T02:43:51Z + regulation of glutamate metabolism + regulation of glutamic acid metabolic process + regulation of glutamic acid metabolism + biological_process + GO:2000211 + regulation of glutamate metabolic process + + + + + Any process that modulates the frequency, rate or extent of glutamate metabolic process. + GOC:sl + + + + + regulation of glutamate metabolism + GOC:obol + + + + + regulation of glutamic acid metabolic process + GOC:obol + + + + + regulation of glutamic acid metabolism + GOC:obol + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of glutamate metabolic process. + mah + 2010-11-03T02:43:55Z + negative regulation of glutamate metabolism + negative regulation of glutamic acid metabolic process + negative regulation of glutamic acid metabolism + biological_process + GO:2000212 + negative regulation of glutamate metabolic process + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of glutamate metabolic process. + GOC:sl + + + + + negative regulation of glutamate metabolism + GOC:obol + + + + + negative regulation of glutamic acid metabolic process + GOC:obol + + + + + negative regulation of glutamic acid metabolism + GOC:obol + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of glutamate metabolic process. + mah + 2010-11-03T02:43:59Z + positive regulation of glutamate metabolism + positive regulation of glutamic acid metabolic process + positive regulation of glutamic acid metabolism + biological_process + GO:2000213 + positive regulation of glutamate metabolic process + + + + + Any process that activates or increases the frequency, rate or extent of glutamate metabolic process. + GOC:sl + + + + + positive regulation of glutamate metabolism + GOC:obol + + + + + positive regulation of glutamic acid metabolic process + GOC:obol + + + + + positive regulation of glutamic acid metabolism + GOC:obol + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of reproductive process. + mah + 2010-11-10T02:44:02Z + biological_process + GO:2000241 + regulation of reproductive process + + + + + Any process that modulates the frequency, rate or extent of reproductive process. + GOC:mah + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of reproductive process. + mah + 2010-11-10T02:44:05Z + biological_process + GO:2000242 + negative regulation of reproductive process + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of reproductive process. + GOC:mah + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of reproductive process. + mah + 2010-11-10T02:44:08Z + biological_process + GO:2000243 + positive regulation of reproductive process + + + + + Any process that activates or increases the frequency, rate or extent of reproductive process. + GOC:mah + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or maintenance of neuroblast polarity. + vw + 2010-11-11T11:40:34Z + negative regulation of establishment and/or maintenance of neuroblast cell polarity + biological_process + GO:2000248 + negative regulation of establishment or maintenance of neuroblast polarity + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or maintenance of neuroblast polarity. + GOC:obol + + + + + negative regulation of establishment and/or maintenance of neuroblast cell polarity + GOC:obol + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of feeding behavior. + yaf + 2010-11-18T11:24:14Z + negative regulation of behavioral response to food + negative regulation of behavioural response to food + negative regulation of feeding behaviour + biological_process + negative regulation of drinking + negative regulation of eating + GO:2000252 + negative regulation of feeding behavior + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of feeding behavior. + GOC:obol + + + + + negative regulation of behavioral response to food + GOC:obol + + + + + negative regulation of behavioural response to food + GOC:obol + + + + + negative regulation of feeding behaviour + GOC:obol + + + + + negative regulation of drinking + GOC:obol + + + + + negative regulation of eating + GOC:obol + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of feeding behavior. + yaf + 2010-11-18T11:24:18Z + positive regulation of behavioral response to food + positive regulation of behavioural response to food + positive regulation of feeding behaviour + biological_process + positive regulation of drinking + positive regulation of eating + GO:2000253 + positive regulation of feeding behavior + + + + + Any process that activates or increases the frequency, rate or extent of feeding behavior. + GOC:obol + + + + + positive regulation of behavioral response to food + GOC:obol + + + + + positive regulation of behavioural response to food + GOC:obol + + + + + positive regulation of feeding behaviour + GOC:obol + + + + + positive regulation of drinking + GOC:obol + + + + + positive regulation of eating + GOC:obol + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of a signaling receptor activity. + bf + 2010-12-02T09:28:47Z + negative regulation of receptor activity + negative regulation of signalling receptor activity + biological_process + GO:2000272 + negative regulation of signaling receptor activity + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of a signaling receptor activity. + GOC:obol + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of signaling receptor activity. + bf + 2010-12-02T09:28:50Z + positive regulation of signalling receptor activity + biological_process + GO:2000273 + positive regulation of signaling receptor activity + + + + + Any process that activates or increases the frequency, rate or extent of signaling receptor activity. + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of cellular amino acid biosynthetic process. + vw + 2010-12-10T11:54:19Z + regulation of amino acid biosynthetic process + regulation of cellular amino acid anabolism + regulation of cellular amino acid biosynthesis + regulation of cellular amino acid formation + regulation of cellular amino acid synthesis + biological_process + GO:2000282 + regulation of cellular amino acid biosynthetic process + + + + + Any process that modulates the frequency, rate or extent of cellular amino acid biosynthetic process. + GOC:obol + + + + + regulation of amino acid biosynthetic process + GOC:obol + + + + + regulation of cellular amino acid anabolism + GOC:obol + + + + + regulation of cellular amino acid biosynthesis + GOC:obol + + + + + regulation of cellular amino acid formation + GOC:obol + + + + + regulation of cellular amino acid synthesis + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cellular amino acid biosynthetic process. + vw + 2010-12-10T11:54:23Z + negative regulation of amino acid biosynthetic process + negative regulation of cellular amino acid anabolism + negative regulation of cellular amino acid biosynthesis + negative regulation of cellular amino acid formation + negative regulation of cellular amino acid synthesis + biological_process + GO:2000283 + negative regulation of cellular amino acid biosynthetic process + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cellular amino acid biosynthetic process. + GOC:obol + + + + + negative regulation of amino acid biosynthetic process + GOC:obol + + + + + negative regulation of cellular amino acid anabolism + GOC:obol + + + + + negative regulation of cellular amino acid biosynthesis + GOC:obol + + + + + negative regulation of cellular amino acid formation + GOC:obol + + + + + negative regulation of cellular amino acid synthesis + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of cellular amino acid biosynthetic process. + vw + 2010-12-10T11:54:27Z + positive regulation of amino acid biosynthetic process + positive regulation of cellular amino acid anabolism + positive regulation of cellular amino acid biosynthesis + positive regulation of cellular amino acid formation + positive regulation of cellular amino acid synthesis + biological_process + GO:2000284 + positive regulation of cellular amino acid biosynthetic process + + + + + Any process that activates or increases the frequency, rate or extent of cellular amino acid biosynthetic process. + GOC:obol + + + + + positive regulation of amino acid biosynthetic process + GOC:obol + + + + + positive regulation of cellular amino acid anabolism + GOC:obol + + + + + positive regulation of cellular amino acid biosynthesis + GOC:obol + + + + + positive regulation of cellular amino acid formation + GOC:obol + + + + + positive regulation of cellular amino acid synthesis + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of myotome development. + rl + 2010-12-16T05:17:15Z + biological_process + GO:2000287 + positive regulation of myotome development + + + + + Any process that activates or increases the frequency, rate or extent of myotome development. + GOC:BHF + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of myotome development. + mah + 2010-12-20T10:22:05Z + biological_process + GO:2000290 + regulation of myotome development + + + + + Any process that modulates the frequency, rate or extent of myotome development. + GOC:mah + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of defecation. + bf + 2010-12-21T09:23:08Z + biological_process + GO:2000292 + regulation of defecation + + + + + Any process that modulates the frequency, rate or extent of defecation. + GOC:obol + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of defecation. + bf + 2010-12-21T09:23:13Z + biological_process + GO:2000293 + negative regulation of defecation + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of defecation. + GOC:obol + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of defecation. + bf + 2010-12-21T09:23:16Z + biological_process + GO:2000294 + positive regulation of defecation + + + + + Any process that activates or increases the frequency, rate or extent of defecation. + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of glucocorticoid receptor signaling pathway. + vk + 2011-01-18T04:38:10Z + regulation of glucocorticoid receptor signalling pathway + biological_process + GO:2000322 + regulation of glucocorticoid receptor signaling pathway + + + + + Any process that modulates the frequency, rate or extent of glucocorticoid receptor signaling pathway. + GOC:BHF + + + + + regulation of glucocorticoid receptor signalling pathway + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid receptor signaling pathway. + vk + 2011-01-18T04:38:43Z + negative regulation of glucocorticoid receptor signalling pathway + biological_process + GO:2000323 + negative regulation of glucocorticoid receptor signaling pathway + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid receptor signaling pathway. + GOC:BHF + + + + + negative regulation of glucocorticoid receptor signalling pathway + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of glucocorticoid receptor signaling pathway. + vk + 2011-01-18T04:39:05Z + positive regulation of glucocorticoid receptor signalling pathway + biological_process + GO:2000324 + positive regulation of glucocorticoid receptor signaling pathway + + + + + Any process that activates or increases the frequency, rate or extent of glucocorticoid receptor signaling pathway. + GOC:BHF + + + + + positive regulation of glucocorticoid receptor signalling pathway + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of ovarian follicle development. + yaf + 2011-02-03T02:01:28Z + biological_process + regulation of follicular phase + GO:2000354 + regulation of ovarian follicle development + + + + + Any process that modulates the frequency, rate or extent of ovarian follicle development. + GOC:obol + + + + + regulation of follicular phase + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of ovarian follicle development. + yaf + 2011-02-03T02:01:32Z + biological_process + negative regulation of follicular phase + GO:2000355 + negative regulation of ovarian follicle development + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of ovarian follicle development. + GOC:obol + + + + + negative regulation of follicular phase + GOC:obol + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of mesoderm development. + vk + 2011-02-15T03:09:46Z + biological_process + GO:2000380 + regulation of mesoderm development + + + + + Any process that modulates the frequency, rate or extent of mesoderm development. + GOC:BHF + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm development. + vk + 2011-02-15T03:10:02Z + biological_process + GO:2000381 + negative regulation of mesoderm development + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm development. + GOC:BHF + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of mesoderm development. + vk + 2011-02-15T03:10:12Z + biological_process + GO:2000382 + positive regulation of mesoderm development + + + + + Any process that activates or increases the frequency, rate or extent of mesoderm development. + GOC:BHF + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of ectoderm development. + vk + 2011-02-15T03:17:10Z + biological_process + GO:2000383 + regulation of ectoderm development + + + + + Any process that modulates the frequency, rate or extent of ectoderm development. + GOC:BHF + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of ectoderm development. + vk + 2011-02-15T03:17:27Z + biological_process + GO:2000384 + negative regulation of ectoderm development + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of ectoderm development. + GOC:BHF + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of ectoderm development. + vk + 2011-02-15T03:17:39Z + biological_process + GO:2000385 + positive regulation of ectoderm development + + + + + Any process that activates or increases the frequency, rate or extent of ectoderm development. + GOC:BHF + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of ovarian follicle development. + yaf + 2011-02-16T02:21:21Z + biological_process + positive regulation of follicular phase + GO:2000386 + positive regulation of ovarian follicle development + + + + + Any process that activates or increases the frequency, rate or extent of ovarian follicle development. + GOC:obol + + + + + positive regulation of follicular phase + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of antral ovarian follicle growth. + yaf + 2011-02-16T04:53:43Z + biological_process + GO:2000387 + regulation of antral ovarian follicle growth + + + + + Any process that modulates the frequency, rate or extent of antral ovarian follicle growth. + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of antral ovarian follicle growth. + yaf + 2011-02-16T04:54:01Z + biological_process + GO:2000388 + positive regulation of antral ovarian follicle growth + + + + + Any process that activates or increases the frequency, rate or extent of antral ovarian follicle growth. + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of lymphocyte migration. + mah + 2011-02-23T10:45:19Z + biological_process + GO:2000401 + regulation of lymphocyte migration + + + + + Any process that modulates the frequency, rate or extent of lymphocyte migration. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte migration. + mah + 2011-02-23T10:45:47Z + biological_process + GO:2000402 + negative regulation of lymphocyte migration + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte migration. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of lymphocyte migration. + mah + 2011-02-23T10:46:06Z + biological_process + GO:2000403 + positive regulation of lymphocyte migration + + + + + Any process that activates or increases the frequency, rate or extent of lymphocyte migration. + GOC:mah + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of T cell migration. + mah + 2011-02-23T10:48:24Z + regulation of T lymphocyte migration + regulation of T-cell migration + regulation of T-lymphocyte migration + biological_process + GO:2000404 + regulation of T cell migration + + + + + Any process that modulates the frequency, rate or extent of T cell migration. + GOC:mah + + + + + regulation of T lymphocyte migration + GOC:obol + + + + + regulation of T-cell migration + GOC:obol + + + + + regulation of T-lymphocyte migration + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of T cell migration. + mah + 2011-02-23T10:48:52Z + negative regulation of T lymphocyte migration + negative regulation of T-cell migration + negative regulation of T-lymphocyte migration + biological_process + GO:2000405 + negative regulation of T cell migration + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of T cell migration. + GOC:mah + + + + + negative regulation of T lymphocyte migration + GOC:obol + + + + + negative regulation of T-cell migration + GOC:obol + + + + + negative regulation of T-lymphocyte migration + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of T cell migration. + mah + 2011-02-23T10:49:12Z + positive regulation of T lymphocyte migration + positive regulation of T-cell migration + positive regulation of T-lymphocyte migration + biological_process + GO:2000406 + positive regulation of T cell migration + + + + + Any process that activates or increases the frequency, rate or extent of T cell migration. + GOC:mah + + + + + positive regulation of T lymphocyte migration + GOC:obol + + + + + positive regulation of T-cell migration + GOC:obol + + + + + positive regulation of T-lymphocyte migration + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of thymocyte migration. + mah + 2011-02-23T01:33:32Z + regulation of thymic lymphocyte migration + biological_process + regulation of immature T cell migration + regulation of immature T lymphocyte migration + regulation of immature T-cell migration + regulation of immature T-lymphocyte migration + GO:2000410 + regulation of thymocyte migration + + + + + Any process that modulates the frequency, rate or extent of thymocyte migration. + GOC:mah + + + + + regulation of thymic lymphocyte migration + GOC:obol + + + + + regulation of immature T cell migration + GOC:obol + + + + + regulation of immature T lymphocyte migration + GOC:obol + + + + + regulation of immature T-cell migration + GOC:obol + + + + + regulation of immature T-lymphocyte migration + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of thymocyte migration. + mah + 2011-02-23T01:34:01Z + negative regulation of thymic lymphocyte migration + biological_process + negative regulation of immature T cell migration + negative regulation of immature T lymphocyte migration + negative regulation of immature T-cell migration + negative regulation of immature T-lymphocyte migration + GO:2000411 + negative regulation of thymocyte migration + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of thymocyte migration. + GOC:mah + + + + + negative regulation of thymic lymphocyte migration + GOC:obol + + + + + negative regulation of immature T cell migration + GOC:obol + + + + + negative regulation of immature T lymphocyte migration + GOC:obol + + + + + negative regulation of immature T-cell migration + GOC:obol + + + + + negative regulation of immature T-lymphocyte migration + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of thymocyte migration. + mah + 2011-02-23T01:34:23Z + positive regulation of thymic lymphocyte migration + biological_process + positive regulation of immature T cell migration + positive regulation of immature T lymphocyte migration + positive regulation of immature T-cell migration + positive regulation of immature T-lymphocyte migration + GO:2000412 + positive regulation of thymocyte migration + + + + + Any process that activates or increases the frequency, rate or extent of thymocyte migration. + GOC:mah + + + + + positive regulation of thymic lymphocyte migration + GOC:obol + + + + + positive regulation of immature T cell migration + GOC:obol + + + + + positive regulation of immature T lymphocyte migration + GOC:obol + + + + + positive regulation of immature T-cell migration + GOC:obol + + + + + positive regulation of immature T-lymphocyte migration + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis. + bf + 2011-03-18T02:18:34Z + biological_process + GO:2000495 + regulation of cell proliferation involved in compound eye morphogenesis + + + + + Any process that modulates the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis. + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis. + bf + 2011-03-18T02:19:22Z + biological_process + GO:2000496 + negative regulation of cell proliferation involved in compound eye morphogenesis + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis. + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis. + bf + 2011-03-18T02:19:54Z + biological_process + GO:2000497 + positive regulation of cell proliferation involved in compound eye morphogenesis + + + + + Any process that activates or increases the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis. + GOC:obol + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of gastrulation. + yaf + 2011-04-01T04:10:08Z + biological_process + GO:2000542 + negative regulation of gastrulation + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of gastrulation. + GOC:obol + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of gastrulation. + yaf + 2011-04-01T04:10:15Z + biological_process + GO:2000543 + positive regulation of gastrulation + + + + + Any process that activates or increases the frequency, rate or extent of gastrulation. + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of dendritic cell dendrite assembly. + ebc + 2011-04-03T07:21:55Z + biological_process + regulation of dendritic extension + GO:2000547 + regulation of dendritic cell dendrite assembly + + + + + Any process that modulates the frequency, rate or extent of dendritic cell dendrite assembly. + GOC:obol + + + + + regulation of dendritic extension + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell dendrite assembly. + ebc + 2011-04-03T07:22:01Z + biological_process + negative regulation of dendritic extension + GO:2000548 + negative regulation of dendritic cell dendrite assembly + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell dendrite assembly. + GOC:obol + + + + + negative regulation of dendritic extension + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of dendritic cell dendrite assembly. + ebc + 2011-04-03T07:22:06Z + biological_process + positive regulation of dendritic extension + GO:2000549 + positive regulation of dendritic cell dendrite assembly + + + + + Any process that activates or increases the frequency, rate or extent of dendritic cell dendrite assembly. + GOC:obol + + + + + positive regulation of dendritic extension + GOC:obol + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of optic nerve formation. + yaf + 2011-04-11T03:41:30Z + biological_process + regulation of CN II biosynthesis + regulation of CN II formation + GO:2000595 + regulation of optic nerve formation + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that modulates the frequency, rate or extent of optic nerve formation. + GOC:obol + + + + + regulation of CN II biosynthesis + GOC:obol + + + + + regulation of CN II formation + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of optic nerve formation. + yaf + 2011-04-11T03:41:35Z + biological_process + negative regulation of CN II biosynthesis + negative regulation of CN II formation + GO:2000596 + negative regulation of optic nerve formation + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of optic nerve formation. + GOC:obol + + + + + negative regulation of CN II biosynthesis + GOC:obol + + + + + negative regulation of CN II formation + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of optic nerve formation. + yaf + 2011-04-11T03:41:39Z + biological_process + positive regulation of CN II biosynthesis + positive regulation of CN II formation + GO:2000597 + positive regulation of optic nerve formation + + + + + Any process that activates or increases the frequency, rate or extent of optic nerve formation. + GOC:obol + + + + + positive regulation of CN II biosynthesis + GOC:obol + + + + + positive regulation of CN II formation + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of cell proliferation involved in mesonephros development. + yaf + 2011-04-18T08:42:19Z + biological_process + GO:2000606 + regulation of cell proliferation involved in mesonephros development + + + + + Any process that modulates the frequency, rate or extent of cell proliferation involved in mesonephros development. + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in mesonephros development. + yaf + 2011-04-18T08:42:23Z + biological_process + GO:2000607 + negative regulation of cell proliferation involved in mesonephros development + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in mesonephros development. + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of cell proliferation involved in mesonephros development. + yaf + 2011-04-18T08:42:25Z + biological_process + GO:2000608 + positive regulation of cell proliferation involved in mesonephros development + + + + + Any process that activates or increases the frequency, rate or extent of cell proliferation involved in mesonephros development. + GOC:obol + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of thyroid hormone generation. + yaf + 2011-04-18T10:12:14Z + biological_process + GO:2000609 + regulation of thyroid hormone generation + + + + + Any process that modulates the frequency, rate or extent of thyroid hormone generation. + GOC:obol + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of thyroid hormone generation. + yaf + 2011-04-18T10:12:19Z + biological_process + GO:2000610 + negative regulation of thyroid hormone generation + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of thyroid hormone generation. + GOC:obol + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of thyroid hormone generation. + yaf + 2011-04-18T10:12:22Z + biological_process + GO:2000611 + positive regulation of thyroid hormone generation + + + + + Any process that activates or increases the frequency, rate or extent of thyroid hormone generation. + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of stem cell proliferation. + dph + 2011-04-27T01:04:22Z + biological_process + GO:2000647 + negative regulation of stem cell proliferation + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of stem cell proliferation. + GOC:dph + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of stem cell proliferation. + dph + 2011-04-27T01:04:25Z + biological_process + GO:2000648 + positive regulation of stem cell proliferation + + + + + Any process that activates or increases the frequency, rate or extent of stem cell proliferation. + GOC:dph + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of epithelial cell differentiation involved in kidney development. + bf + 2011-05-16T04:23:52Z + biological_process + GO:2000696 + regulation of epithelial cell differentiation involved in kidney development + + + + + Any process that modulates the frequency, rate or extent of epithelial cell differentiation involved in kidney development. + GOC:mtg_kidney_jan10 + GOC:yaf + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell differentiation involved in kidney development. + bf + 2011-05-16T04:23:55Z + biological_process + GO:2000697 + negative regulation of epithelial cell differentiation involved in kidney development + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell differentiation involved in kidney development. + GOC:mtg_kidney_jan10 + GOC:yaf + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation involved in kidney development. + bf + 2011-05-16T04:23:57Z + biological_process + GO:2000698 + positive regulation of epithelial cell differentiation involved in kidney development + + + + + Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation involved in kidney development. + GOC:mtg_kidney_jan10 + GOC:yaf + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of cardiac muscle cell differentiation. + vk + 2011-06-08T10:51:06Z + regulation of cardiomyocyte differentiation + biological_process + regulation of heart muscle cell differentiation + GO:2000725 + regulation of cardiac muscle cell differentiation + + + + + Any process that modulates the frequency, rate or extent of cardiac muscle cell differentiation. + GOC:BHF + + + + + regulation of cardiomyocyte differentiation + GOC:obol + + + + + regulation of heart muscle cell differentiation + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell differentiation. + vk + 2011-06-08T10:51:11Z + negative regulation of cardiomyocyte differentiation + biological_process + negative regulation of heart muscle cell differentiation + GO:2000726 + negative regulation of cardiac muscle cell differentiation + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell differentiation. + GOC:BHF + + + + + negative regulation of cardiomyocyte differentiation + GOC:obol + + + + + negative regulation of heart muscle cell differentiation + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of cardiac muscle cell differentiation. + vk + 2011-06-08T10:51:15Z + positive regulation of cardiomyocyte differentiation + biological_process + positive regulation of heart muscle cell differentiation + GO:2000727 + positive regulation of cardiac muscle cell differentiation + + + + + Any process that activates or increases the frequency, rate or extent of cardiac muscle cell differentiation. + GOC:BHF + + + + + positive regulation of cardiomyocyte differentiation + GOC:obol + + + + + positive regulation of heart muscle cell differentiation + GOC:obol + + + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of mesenchymal cell proliferation involved in ureter development. + yaf + 2011-06-10T02:27:19Z + biological_process + positive regulation of ureter mesenchymal cell proliferation + positive regulation of ureteral mesenchymal cell proliferation + GO:2000729 + positive regulation of mesenchymal cell proliferation involved in ureter development + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that activates or increases the frequency, rate or extent of mesenchymal cell proliferation involved in ureter development. + GOC:obol + + + + + positive regulation of ureter mesenchymal cell proliferation + GOC:obol + + + + + positive regulation of ureteral mesenchymal cell proliferation + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of stem cell differentiation. + yaf + 2011-06-14T02:05:16Z + biological_process + GO:2000736 + regulation of stem cell differentiation + + + + + Any process that modulates the frequency, rate or extent of stem cell differentiation. + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation. + yaf + 2011-06-14T02:05:20Z + biological_process + GO:2000737 + negative regulation of stem cell differentiation + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation. + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of stem cell differentiation. + yaf + 2011-06-14T02:05:23Z + biological_process + GO:2000738 + positive regulation of stem cell differentiation + + + + + Any process that activates or increases the frequency, rate or extent of stem cell differentiation. + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation involved in lung development. + pr + 2011-06-24T01:53:50Z + biological_process + GO:2000790 + regulation of mesenchymal cell proliferation involved in lung development + + + + + Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation involved in lung development. + PMID:21513708 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell proliferation involved in lung development. + pr + 2011-06-24T01:53:53Z + biological_process + GO:2000791 + negative regulation of mesenchymal cell proliferation involved in lung development + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell proliferation involved in lung development. + PMID:21513708 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of mesenchymal cell proliferation involved in lung development. + pr + 2011-06-24T01:53:56Z + biological_process + GO:2000792 + positive regulation of mesenchymal cell proliferation involved in lung development + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + + + + + + + https://github.com/geneontology/go-ontology/issues/13926 + + + + + Any process that activates or increases the frequency, rate or extent of mesenchymal cell proliferation involved in lung development. + PMID:21513708 + + + + + + + + + + + + + + + + + + + Any cell proliferation that is involved in heart valve development. + bf + 2011-06-24T03:12:15Z + cell proliferation of cardiac valve development + cell proliferation of heart valve development + biological_process + GO:2000793 + cell proliferation involved in heart valve development + + + + + Any cell proliferation that is involved in heart valve development. + GOC:BHF + + + + + cell proliferation of cardiac valve development + GOC:obol + + + + + cell proliferation of heart valve development + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis. + pr + 2011-06-25T07:22:38Z + biological_process + GO:2000794 + regulation of epithelial cell proliferation involved in lung morphogenesis + + + + + Any process that modulates the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis. + PMID:21513708 + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis. + pr + 2011-06-25T07:22:42Z + biological_process + GO:2000795 + negative regulation of epithelial cell proliferation involved in lung morphogenesis + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis. + PMID:21513708 + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of tight junction assembly. + vk + 2011-07-06T01:08:28Z + regulation of tight junction formation + biological_process + GO:2000810 + regulation of bicellular tight junction assembly + + + + + Any process that modulates the frequency, rate or extent of tight junction assembly. + GOC:BHF + + + + + regulation of tight junction formation + GOC:obol + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of grooming behavior. + rl + 2011-07-14T04:48:12Z + regulation of grooming behaviour + biological_process + GO:2000821 + regulation of grooming behavior + + + + + Any process that modulates the frequency, rate or extent of grooming behavior. + GOC:BHF + + + + + regulation of grooming behaviour + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of heart morphogenesis. + vk + 2011-07-19T10:08:58Z + biological_process + regulation of cardiac morphogenesis + GO:2000826 + regulation of heart morphogenesis + + + + + Any process that modulates the frequency, rate or extent of heart morphogenesis. + GOC:BHF + + + + + regulation of cardiac morphogenesis + GOC:obol + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of parathyroid hormone secretion. + bf + 2011-07-26T08:37:53Z + regulation of PTH secretion + regulation of parathormone secretion + regulation of parathyrin secretion + biological_process + GO:2000828 + regulation of parathyroid hormone secretion + + + + + Any process that modulates the frequency, rate or extent of parathyroid hormone secretion. + GOC:obol + + + + + regulation of PTH secretion + GOC:obol + + + + + regulation of parathormone secretion + GOC:obol + + + + + regulation of parathyrin secretion + GOC:obol + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of parathyroid hormone secretion. + bf + 2011-07-26T08:37:57Z + negative regulation of PTH secretion + negative regulation of parathormone secretion + negative regulation of parathyrin secretion + biological_process + GO:2000829 + negative regulation of parathyroid hormone secretion + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of parathyroid hormone secretion. + GOC:obol + + + + + negative regulation of PTH secretion + GOC:obol + + + + + negative regulation of parathormone secretion + GOC:obol + + + + + negative regulation of parathyrin secretion + GOC:obol + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of parathyroid hormone secretion. + bf + 2011-07-26T08:38:00Z + positive regulation of PTH secretion + positive regulation of parathormone secretion + positive regulation of parathyrin secretion + biological_process + GO:2000830 + positive regulation of parathyroid hormone secretion + + + + + Any process that activates or increases the frequency, rate or extent of parathyroid hormone secretion. + GOC:obol + + + + + positive regulation of PTH secretion + GOC:obol + + + + + positive regulation of parathormone secretion + GOC:obol + + + + + positive regulation of parathyrin secretion + GOC:obol + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of steroid hormone secretion. + bf + 2011-07-26T08:38:46Z + biological_process + GO:2000831 + regulation of steroid hormone secretion + + + + + Any process that modulates the frequency, rate or extent of steroid hormone secretion. + GOC:sl + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of steroid hormone secretion. + bf + 2011-07-26T08:38:50Z + biological_process + GO:2000832 + negative regulation of steroid hormone secretion + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of steroid hormone secretion. + GOC:sl + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of steroid hormone secretion. + bf + 2011-07-26T08:38:51Z + biological_process + GO:2000833 + positive regulation of steroid hormone secretion + + + + + Any process that activates or increases the frequency, rate or extent of steroid hormone secretion. + GOC:sl + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of corticosteroid hormone secretion. + bf + 2011-07-26T08:43:38Z + biological_process + regulation of corticosteroid secretion + GO:2000846 + regulation of corticosteroid hormone secretion + + + + + Any process that modulates the frequency, rate or extent of corticosteroid hormone secretion. + GOC:sl + + + + + regulation of corticosteroid secretion + GOC:obol + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of corticosteroid hormone secretion. + bf + 2011-07-26T08:43:42Z + biological_process + negative regulation of corticosteroid secretion + GO:2000847 + negative regulation of corticosteroid hormone secretion + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of corticosteroid hormone secretion. + GOC:sl + + + + + negative regulation of corticosteroid secretion + GOC:obol + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of corticosteroid hormone secretion. + bf + 2011-07-26T08:43:45Z + biological_process + positive regulation of corticosteroid secretion + GO:2000848 + positive regulation of corticosteroid hormone secretion + + + + + Any process that activates or increases the frequency, rate or extent of corticosteroid hormone secretion. + GOC:sl + + + + + positive regulation of corticosteroid secretion + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of glucocorticoid secretion. + bf + 2011-07-26T08:44:43Z + biological_process + GO:2000849 + regulation of glucocorticoid secretion + + + + + Any process that modulates the frequency, rate or extent of glucocorticoid secretion. + GOC:sl + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid secretion. + bf + 2011-07-26T08:44:48Z + biological_process + GO:2000850 + negative regulation of glucocorticoid secretion + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid secretion. + GOC:sl + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of glucocorticoid secretion. + bf + 2011-07-26T08:44:51Z + biological_process + GO:2000851 + positive regulation of glucocorticoid secretion + + + + + Any process that activates or increases the frequency, rate or extent of glucocorticoid secretion. + GOC:sl + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of mineralocorticoid secretion. + bf + 2011-07-26T08:46:38Z + biological_process + GO:2000855 + regulation of mineralocorticoid secretion + + + + + Any process that modulates the frequency, rate or extent of mineralocorticoid secretion. + GOC:sl + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of mineralocorticoid secretion. + bf + 2011-07-26T08:46:42Z + biological_process + GO:2000856 + negative regulation of mineralocorticoid secretion + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of mineralocorticoid secretion. + GOC:sl + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of mineralocorticoid secretion. + bf + 2011-07-26T08:46:45Z + biological_process + GO:2000857 + positive regulation of mineralocorticoid secretion + + + + + Any process that activates or increases the frequency, rate or extent of mineralocorticoid secretion. + GOC:sl + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of aldosterone secretion. + bf + 2011-07-26T08:47:27Z + biological_process + GO:2000858 + regulation of aldosterone secretion + + + + + Any process that modulates the frequency, rate or extent of aldosterone secretion. + GOC:sl + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of aldosterone secretion. + bf + 2011-07-26T08:47:31Z + biological_process + GO:2000859 + negative regulation of aldosterone secretion + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of aldosterone secretion. + GOC:sl + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of aldosterone secretion. + bf + 2011-07-26T08:47:34Z + biological_process + GO:2000860 + positive regulation of aldosterone secretion + + + + + Any process that activates or increases the frequency, rate or extent of aldosterone secretion. + GOC:sl + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of progesterone secretion. + bf + 2011-07-26T08:51:14Z + biological_process + GO:2000870 + regulation of progesterone secretion + + + + + Any process that modulates the frequency, rate or extent of progesterone secretion. + GOC:sl + + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of progesterone secretion. + bf + 2011-07-26T08:51:19Z + biological_process + GO:2000871 + negative regulation of progesterone secretion + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of progesterone secretion. + GOC:sl + + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of progesterone secretion. + bf + 2011-07-26T08:51:22Z + biological_process + GO:2000872 + positive regulation of progesterone secretion + + + + + Any process that activates or increases the frequency, rate or extent of progesterone secretion. + GOC:sl + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of forebrain neuron differentiation. + yaf + 2011-08-03T12:09:12Z + biological_process + GO:2000977 + regulation of forebrain neuron differentiation + + + + + Any process that modulates the frequency, rate or extent of forebrain neuron differentiation. + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of forebrain neuron differentiation. + yaf + 2011-08-03T12:09:16Z + biological_process + GO:2000978 + negative regulation of forebrain neuron differentiation + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of forebrain neuron differentiation. + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of forebrain neuron differentiation. + yaf + 2011-08-03T12:09:19Z + biological_process + GO:2000979 + positive regulation of forebrain neuron differentiation + + + + + Any process that activates or increases the frequency, rate or extent of forebrain neuron differentiation. + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of inner ear receptor cell differentiation. + yaf + 2011-08-03T02:38:43Z + regulation of inner ear hair cell differentiation + biological_process + GO:2000980 + regulation of inner ear receptor cell differentiation + + + + + Any process that modulates the frequency, rate or extent of inner ear receptor cell differentiation. + GOC:obol + + + + + regulation of inner ear hair cell differentiation + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of inner ear receptor cell differentiation. + yaf + 2011-08-03T02:38:47Z + negative regulation of inner ear hair cell differentiation + biological_process + GO:2000981 + negative regulation of inner ear receptor cell differentiation + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of inner ear receptor cell differentiation. + GOC:obol + + + + + negative regulation of inner ear hair cell differentiation + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of inner ear receptor cell differentiation. + yaf + 2011-08-03T02:38:51Z + positive regulation of inner ear hair cell differentiation + biological_process + GO:2000982 + positive regulation of inner ear receptor cell differentiation + + + + + Any process that activates or increases the frequency, rate or extent of inner ear receptor cell differentiation. + GOC:obol + + + + + positive regulation of inner ear hair cell differentiation + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of cellulose catabolic process. + tt + 2011-08-08T03:21:20Z + regulation of cellulose breakdown + regulation of cellulose catabolism + regulation of cellulose degradation + biological_process + GO:2000997 + regulation of cellulose catabolic process + + + + + Any process that modulates the frequency, rate or extent of cellulose catabolic process. + GOC:mengo_curators + + + + + regulation of cellulose breakdown + GOC:obol + + + + + regulation of cellulose catabolism + GOC:obol + + + + + regulation of cellulose degradation + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cellulose catabolic process. + tt + 2011-08-08T03:21:26Z + negative regulation of cellulose breakdown + negative regulation of cellulose catabolism + negative regulation of cellulose degradation + biological_process + GO:2000998 + negative regulation of cellulose catabolic process + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cellulose catabolic process. + GOC:mengo_curators + + + + + negative regulation of cellulose breakdown + GOC:obol + + + + + negative regulation of cellulose catabolism + GOC:obol + + + + + negative regulation of cellulose degradation + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of cellulose catabolic process. + tt + 2011-08-08T03:21:30Z + positive regulation of cellulose breakdown + positive regulation of cellulose catabolism + positive regulation of cellulose degradation + biological_process + GO:2000999 + positive regulation of cellulose catabolic process + + + + + Any process that activates or increases the frequency, rate or extent of cellulose catabolic process. + GOC:mengo_curators + + + + + positive regulation of cellulose breakdown + GOC:obol + + + + + positive regulation of cellulose catabolism + GOC:obol + + + + + positive regulation of cellulose degradation + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of cellulose biosynthetic process. + tt + 2011-08-08T08:42:17Z + regulation of cellulose anabolism + regulation of cellulose biosynthesis + regulation of cellulose formation + regulation of cellulose synthesis + biological_process + GO:2001006 + regulation of cellulose biosynthetic process + + + + + Any process that modulates the frequency, rate or extent of cellulose biosynthetic process. + GOC:mengo_curators + + + + + regulation of cellulose anabolism + GOC:obol + + + + + regulation of cellulose biosynthesis + GOC:obol + + + + + regulation of cellulose formation + GOC:obol + + + + + regulation of cellulose synthesis + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cellulose biosynthetic process. + tt + 2011-08-08T08:42:24Z + negative regulation of cellulose anabolism + negative regulation of cellulose biosynthesis + negative regulation of cellulose formation + negative regulation of cellulose synthesis + biological_process + GO:2001007 + negative regulation of cellulose biosynthetic process + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of cellulose biosynthetic process. + GOC:mengo_curators + + + + + negative regulation of cellulose anabolism + GOC:obol + + + + + negative regulation of cellulose biosynthesis + GOC:obol + + + + + negative regulation of cellulose formation + GOC:obol + + + + + negative regulation of cellulose synthesis + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of cellulose biosynthetic process. + tt + 2011-08-08T08:42:29Z + positive regulation of cellulose anabolism + positive regulation of cellulose biosynthesis + positive regulation of cellulose formation + positive regulation of cellulose synthesis + biological_process + GO:2001008 + positive regulation of cellulose biosynthetic process + + + + + Any process that activates or increases the frequency, rate or extent of cellulose biosynthetic process. + GOC:mengo_curators + + + + + positive regulation of cellulose anabolism + GOC:obol + + + + + positive regulation of cellulose biosynthesis + GOC:obol + + + + + positive regulation of cellulose formation + GOC:obol + + + + + positive regulation of cellulose synthesis + GOC:obol + + + + + + + + + + + + + + + + + + + The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the renal system as it progresses from its formation to the mature state. + yaf + 2011-08-09T04:05:14Z + biological_process + mesenchymal cell differentiation involved in urinary system development + mesenchymal cell differentiation involved in urinary tract development + GO:2001012 + mesenchymal cell differentiation involved in renal system development + + + + + The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the renal system as it progresses from its formation to the mature state. + GOC:mtg_kidney_jan10 + GOC:obol + GOC:yaf + + + + + mesenchymal cell differentiation involved in urinary system development + GOC:obol + + + + + mesenchymal cell differentiation involved in urinary tract development + GOC:obol + + + + + + + + + + + + + + + + + + + Any epithelial cell proliferation that is involved in renal tubule morphogenesis. + yaf + 2011-08-12T11:37:29Z + biological_process + GO:2001013 + epithelial cell proliferation involved in renal tubule morphogenesis + + + + + Any epithelial cell proliferation that is involved in renal tubule morphogenesis. + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of skeletal muscle cell differentiation. + yaf + 2011-08-11T08:54:37Z + biological_process + GO:2001014 + regulation of skeletal muscle cell differentiation + + + + + Any process that modulates the frequency, rate or extent of skeletal muscle cell differentiation. + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle cell differentiation. + yaf + 2011-08-11T08:54:41Z + biological_process + GO:2001015 + negative regulation of skeletal muscle cell differentiation + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle cell differentiation. + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of skeletal muscle cell differentiation. + yaf + 2011-08-11T08:54:44Z + biological_process + GO:2001016 + positive regulation of skeletal muscle cell differentiation + + + + + Any process that activates or increases the frequency, rate or extent of skeletal muscle cell differentiation. + GOC:obol + + + + + + + + + + + + + + + + + + + Binding to glycogen. + jl + 2011-09-14T12:01:06Z + molecular_function + animal starch binding + liver starch binding + GO:2001069 + glycogen binding + + + + + Binding to glycogen. + GOC:mengo_curators + + + + + animal starch binding + GOC:obol + + + + + liver starch binding + GOC:obol + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of renal water transport. + yaf + 2011-10-24T11:37:51Z + biological_process + GO:2001151 + regulation of renal water transport + + + + + Any process that modulates the frequency, rate or extent of renal water transport. + GOC:obol + + + + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of renal water transport. + yaf + 2011-10-24T11:37:57Z + biological_process + GO:2001152 + negative regulation of renal water transport + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of renal water transport. + GOC:obol + + + + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of renal water transport. + yaf + 2011-10-24T11:38:01Z + biological_process + GO:2001153 + positive regulation of renal water transport + + + + + Any process that activates or increases the frequency, rate or extent of renal water transport. + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of dendritic cell differentiation. + yaf + 2011-11-04T02:01:27Z + biological_process + GO:2001198 + regulation of dendritic cell differentiation + + + + + Any process that modulates the frequency, rate or extent of dendritic cell differentiation. + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell differentiation. + yaf + 2011-11-04T02:01:33Z + biological_process + GO:2001199 + negative regulation of dendritic cell differentiation + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell differentiation. + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of dendritic cell differentiation. + yaf + 2011-11-04T02:01:36Z + biological_process + GO:2001200 + positive regulation of dendritic cell differentiation + + + + + Any process that activates or increases the frequency, rate or extent of dendritic cell differentiation. + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of vasculogenesis. + yaf + 2011-11-15T01:22:31Z + regulation of vascular morphogenesis + biological_process + GO:2001212 + regulation of vasculogenesis + + + + + Any process that modulates the frequency, rate or extent of vasculogenesis. + GOC:obol + + + + + regulation of vascular morphogenesis + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of vasculogenesis. + yaf + 2011-11-15T01:22:36Z + negative regulation of vascular morphogenesis + biological_process + GO:2001213 + negative regulation of vasculogenesis + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of vasculogenesis. + GOC:obol + + + + + negative regulation of vascular morphogenesis + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of vasculogenesis. + yaf + 2011-11-15T01:22:39Z + positive regulation of vascular morphogenesis + biological_process + GO:2001214 + positive regulation of vasculogenesis + + + + + Any process that activates or increases the frequency, rate or extent of vasculogenesis. + GOC:obol + + + + + positive regulation of vascular morphogenesis + GOC:obol + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + Any process that modulates the frequency, rate or extent of neuron migration. + kmv + 2011-11-17T10:01:38Z + regulation of neuron chemotaxis + regulation of neuronal migration + biological_process + regulation of neuron guidance + GO:2001222 + regulation of neuron migration + + + + + Any process that modulates the frequency, rate or extent of neuron migration. + GOC:obol + + + + + regulation of neuron chemotaxis + GOC:obol + + + + + regulation of neuronal migration + GOC:obol + + + + + regulation of neuron guidance + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of neuron migration. + kmv + 2011-11-17T10:01:45Z + negative regulation of neuron chemotaxis + negative regulation of neuronal migration + biological_process + negative regulation of neuron guidance + GO:2001223 + negative regulation of neuron migration + + + + + Any process that stops, prevents or reduces the frequency, rate or extent of neuron migration. + GOC:obol + + + + + negative regulation of neuron chemotaxis + GOC:obol + + + + + negative regulation of neuronal migration + GOC:obol + + + + + negative regulation of neuron guidance + GOC:obol + + + + + + + + + + + + + + + + + + + Any process that activates or increases the frequency, rate or extent of neuron migration. + kmv + 2011-11-17T10:01:49Z + positive regulation of neuron chemotaxis + positive regulation of neuronal migration + biological_process + positive regulation of neuron guidance + GO:2001224 + positive regulation of neuron migration + + + + + Any process that activates or increases the frequency, rate or extent of neuron migration. + GOC:obol + + + + + positive regulation of neuron chemotaxis + GOC:obol + + + + + positive regulation of neuronal migration + GOC:obol + + + + + positive regulation of neuron guidance + GOC:obol + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + 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