diff --git a/src/ontology/mp-edit.owl b/src/ontology/mp-edit.owl index e9ff471c..9a5fe713 100644 --- a/src/ontology/mp-edit.owl +++ b/src/ontology/mp-edit.owl @@ -18455,9 +18455,9 @@ SubClassOf( (increased cranium width) AnnotationAssertion(Annotation( "MGI:csmith") "having an increased side-to-side, or lateral distance of the cranium") +AnnotationAssertion( "increased skull width") +AnnotationAssertion( "wide skull") AnnotationAssertion( "MPheno.ontology") -AnnotationAssertion( "increased skull width") -AnnotationAssertion( "wide skull") AnnotationAssertion( "MP:0000441") AnnotationAssertion(rdfs:label "increased cranium width") EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )))) @@ -20339,12 +20339,12 @@ SubClassOf( "ISBN:0-683-40008-8") "greater than the expected number of a malignant neoplasm of the secreting cells of the salivary gland, occurring in a specific population in a given time period") AnnotationAssertion( "MP:0002040") -AnnotationAssertion( "Salivary Adenocarcinomas") -AnnotationAssertion( "acinar carcinoma") -AnnotationAssertion( "acinic cell adenocarcinoma") -AnnotationAssertion( "acinic cell carcinoma") AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "salivary adenocarcinoma") +AnnotationAssertion( "Salivary Adenocarcinomas") +AnnotationAssertion( "acinar carcinoma") +AnnotationAssertion( "acinic cell adenocarcinoma") +AnnotationAssertion( "acinic cell carcinoma") AnnotationAssertion( "MP:0000621") AnnotationAssertion(rdfs:label "increased salivary adenocarcinoma incidence") EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( )))) @@ -28964,12 +28964,12 @@ SubClassOf( "ISBN:0-683-40008-8") "any anomaly in the blood concentrations of the fatty acids which occur in plasma as a result of lipolysis in adipose tissue or when plasma triacyglycerols are taken into tissues") AnnotationAssertion( "abnormal FFA level") -AnnotationAssertion( "abnormal UFA level") +AnnotationAssertion( "abnormal NEFA level") +AnnotationAssertion( "abnormal UFA level") +AnnotationAssertion( "abnormal unesterified fatty acids level") AnnotationAssertion( "abnormal circulating non-esterified fatty acids level") -AnnotationAssertion( "abnormal unesterified fatty acids level") +AnnotationAssertion( "abnormal circulating free fatty acid level") AnnotationAssertion( "MPheno.ontology") -AnnotationAssertion( "abnormal NEFA level") -AnnotationAssertion( "abnormal circulating free fatty acid level") AnnotationAssertion( "MP:0001553") AnnotationAssertion(rdfs:label "abnormal circulating free fatty acids level") EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( )))) @@ -31534,11 +31534,11 @@ SubClassOf( "MGI:smb") "higher than normal incidence of malignant tumors of the mammary gland") AnnotationAssertion( "MP:0002011") -AnnotationAssertion( "mammary adenocarcinoma") -AnnotationAssertion( "mammary carcinoma") -AnnotationAssertion( "mammary gland adenocarcinoma") -AnnotationAssertion( "mammary gland carcinoma") AnnotationAssertion( "MPheno.ontology") +AnnotationAssertion( "mammary adenocarcinoma") +AnnotationAssertion( "mammary carcinoma") +AnnotationAssertion( "mammary gland adenocarcinoma") +AnnotationAssertion( "mammary gland carcinoma") AnnotationAssertion( "MP:0001883") AnnotationAssertion(rdfs:label "increased mammary adenocarcinoma incidence") EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( )))) @@ -32618,12 +32618,12 @@ SubClassOf( (increased pilomatricoma incidence) AnnotationAssertion(Annotation( "MGI:csmith") Annotation( "http://atlasgeneticsoncology.org/Tumors/PilomatricomaID5153.html") "greater than the expected number of neoplasms that arise from hair matrix cells occurring in a specific population in a given time period; pilomatricoma is an encapsulated tumor containing irregularly shaped, lobules of cells separated by fibrovascular connective tissue stroma; two distinct cell populations comprise this tumor, basaloid cells with scant cytoplasm located towards the periphery and the ghost (or shadow) cells occupying the central portion") -AnnotationAssertion( "calcifying epithelioma") -AnnotationAssertion( "calcifying epithelioma of Malherbe") -AnnotationAssertion( "epithelioma of Malherbe") -AnnotationAssertion( "pilomatrixoma") -AnnotationAssertion( "trichomatricoma") AnnotationAssertion( "MPheno.ontology") +AnnotationAssertion( "calcifying epithelioma") +AnnotationAssertion( "calcifying epithelioma of Malherbe") +AnnotationAssertion( "epithelioma of Malherbe") +AnnotationAssertion( "pilomatrixoma") +AnnotationAssertion( "trichomatricoma") AnnotationAssertion( "MP:0002013") AnnotationAssertion(rdfs:label "increased pilomatricoma incidence") EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )))) @@ -32711,9 +32711,9 @@ SubClassOf( (increased B cell derived lymphoma incidence) AnnotationAssertion(Annotation( "MESH:C04.557.386.480.150") "higher than normal incidence of heterogeneous lymphoid tumors generally expressing one or more B-cell antigens or representing malignant transformations of B-lymphocytes") -AnnotationAssertion( "B-cell derived lymphoma") AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "B cell derived lymphoma") +AnnotationAssertion( "B-cell derived lymphoma") AnnotationAssertion( "MP:0002023") AnnotationAssertion(rdfs:label "increased B cell derived lymphoma incidence") EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )))) @@ -32724,7 +32724,6 @@ SubClassOf( "MESH:C04.557.386.480.750") "higher than normal incidence of a group of heterogeneous lymphoid tumors representing malignant transformations of T-lymphocytes") AnnotationAssertion( "MP:0003832") AnnotationAssertion( "MP:0005234") -AnnotationAssertion( "T-cell derived lymphoma") AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "T cell derived lymphoma") AnnotationAssertion( "thymic lymphoma") @@ -32732,6 +32731,7 @@ AnnotationAssertion( "thymic tumour") AnnotationAssertion( "thymus tumor") AnnotationAssertion( "thymus tumour") +AnnotationAssertion( "T-cell derived lymphoma") AnnotationAssertion( "MP:0002024") AnnotationAssertion(rdfs:label "increased T cell derived lymphoma incidence") EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )))) @@ -32777,14 +32777,14 @@ SubClassOf( "ISBN:0-683-40008-8") "greater than the expected number of a highly aggressive malignant neoplasm arising from the fibrous connective tissue surrounding peripheral nerves, in a specific population in a given time period") AnnotationAssertion( "MP:0002034") -AnnotationAssertion( "MPNSTs") AnnotationAssertion( "increased fibroblastic neurosarcoma incidence") -AnnotationAssertion( "malignant peripheral nerve sheath tumors") -AnnotationAssertion( "malignant peripheral nerve sheath tumours") -AnnotationAssertion( "peripheral nerve sheath tumor") -AnnotationAssertion( "peripheral nerve sheath tumour") AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "malignant neurolemmoma") +AnnotationAssertion( "MPNSTs") +AnnotationAssertion( "malignant peripheral nerve sheath tumors") +AnnotationAssertion( "malignant peripheral nerve sheath tumours") +AnnotationAssertion( "peripheral nerve sheath tumor") +AnnotationAssertion( "peripheral nerve sheath tumour") AnnotationAssertion( "MP:0002030") AnnotationAssertion(rdfs:label "increased neurofibrosarcoma incidence") EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( )))) @@ -32814,11 +32814,11 @@ SubClassOf( (increased malignant triton tumor incidence) AnnotationAssertion(Annotation( "ISBN:0-683-40008-8") "greater than the expected number of a malignant tumor with neurogenic and myogenic differentiation, occurring in a specific population in a given time period; usually arises in tissues of neural crest origin") -AnnotationAssertion( "MTTs") AnnotationAssertion( "increased malignant triton tumour incidence") AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "malignant triton tumors") AnnotationAssertion( "malignant triton tumours") +AnnotationAssertion( "MTTs") AnnotationAssertion( "MP:0002033") AnnotationAssertion(rdfs:label "increased malignant triton tumor incidence") SubClassOf( ) @@ -32826,8 +32826,8 @@ SubClassOf( (increased leiomyosarcoma incidence) AnnotationAssertion(Annotation( "ISBN:0-683-40008-8") "greater than the expected number of a malignant tumor derived from smooth (nonstriated) muscle, occurring in a specific population in a given time period") -AnnotationAssertion( "leiomyosarcoma") AnnotationAssertion( "MPheno.ontology") +AnnotationAssertion( "leiomyosarcoma") AnnotationAssertion( "MP:0002035") AnnotationAssertion(rdfs:label "increased leiomyosarcoma incidence") EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )))) @@ -32837,8 +32837,8 @@ SubClassOf( (increased rhabdomyosarcoma incidence) AnnotationAssertion(Annotation( "ISBN:0-683-40008-8") "greater than the expected number of a malignant tumor derived from skeletal (striated) muscle, occurring in a specific population in a given time period") -AnnotationAssertion( "rhabdomyosarcoma") AnnotationAssertion( "MPheno.ontology") +AnnotationAssertion( "rhabdomyosarcoma") AnnotationAssertion( "MP:0002036") AnnotationAssertion(rdfs:label "increased rhabdomyosarcoma incidence") EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )))) @@ -32848,8 +32848,8 @@ SubClassOf( (increased fibrohistocytoma incidence) AnnotationAssertion(Annotation( "ISBN:0-683-40008-8") "greater than the expected number of slowly growing skin nodules derived from cellular fibrous tissue occurring in a specific population in a given time period; these often surround capillaries") -AnnotationAssertion( "dermatofibroma") AnnotationAssertion( "MPheno.ontology") +AnnotationAssertion( "dermatofibroma") AnnotationAssertion( "MP:0002037") AnnotationAssertion(rdfs:label "increased fibrohistocytoma incidence") SubClassOf( ) @@ -32934,10 +32934,10 @@ SubClassOf( "ISBN:0-683-40008-8") Annotation( "MGI:csmith") "greater than the expected number of a benign tumor characterized by blood-filled spaces lined by benign endothelial cells in the liver, occurring in a specific population in a given time period") AnnotationAssertion( "increased hepatic haemangioma incidence") -AnnotationAssertion( "liver angioma") AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "hepatic haemangioma") AnnotationAssertion( "hepatic hemangioma") +AnnotationAssertion( "liver angioma") AnnotationAssertion( "MP:0002047") AnnotationAssertion(rdfs:label "increased hepatic hemangioma incidence") EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( )))) @@ -32979,8 +32979,8 @@ SubClassOf( (increased skin papilloma incidence) AnnotationAssertion(Annotation( "ISBN:0-683-40008-8") "greater than the expected number of a circumscribed, benign epithelial tumor projecting from the surrounding surface, occurring in a specific population in a given time period") -AnnotationAssertion( "skin papilloma") AnnotationAssertion( "MPheno.ontology") +AnnotationAssertion( "skin papilloma") AnnotationAssertion( "MP:0002051") AnnotationAssertion(rdfs:label "increased skin papilloma incidence") EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( )))) @@ -33370,11 +33370,11 @@ SubClassOf( "MGI:csmith") "death anytime within the perinatal period (Mus: E18.5 through postnatal day 1)") AnnotationAssertion( "MP:0001644") -AnnotationAssertion( "stillborn") AnnotationAssertion( "MGI:2173526") AnnotationAssertion( "perinatal death") AnnotationAssertion( "survival: perinatal lethality") AnnotationAssertion( "MPheno.ontology") +AnnotationAssertion( "stillborn") AnnotationAssertion( "MP:0002081") AnnotationAssertion(rdfs:label "perinatal lethality") SubClassOf( ) @@ -39981,8 +39981,8 @@ SubClassOf( (increased trichoepithelioma incidence) AnnotationAssertion(Annotation( "MGI:il") "greater than the expected number of benign hair follicle tumors that lack mature hair follicles, derived from basal cells of the hair follicles enclosing small keratin cysts, occurring in a specific population in a given time period") -AnnotationAssertion( "trichoepithelioma") AnnotationAssertion( "MPheno.ontology") +AnnotationAssertion( "trichoepithelioma") AnnotationAssertion( "MP:0002732") AnnotationAssertion(rdfs:label "increased trichoepithelioma incidence") EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )))) @@ -44713,7 +44713,7 @@ SubClassOf( (calcified skin) AnnotationAssertion(Annotation( "RGD:cur") "pathologic deposition of calcium salts in the skin") -AnnotationAssertion( "skin calcification") +AnnotationAssertion( "skin calcification") AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "MP:0003196") AnnotationAssertion(rdfs:label "calcified skin") @@ -45621,10 +45621,10 @@ SubClassOf( ObjectSomeValuesFrom( "MGI:csmith") Annotation( "NCBI:matt") "greater than the expected number of a benign tumor characterized by blood-filled spaces lined by benign endothelial cells in the intestines, occurring in a specific population in a given time period") AnnotationAssertion( "increased intestinal haemangioma incidence") -AnnotationAssertion( "intestinal angioma") AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "intestinal haemangioma") AnnotationAssertion( "intestinal hemangioma") +AnnotationAssertion( "intestinal angioma") AnnotationAssertion( "MP:0003287") AnnotationAssertion(rdfs:label "increased intestinal hemangioma incidence") EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( )))) @@ -46072,10 +46072,10 @@ AnnotationAssertion( "liver neoplasia") AnnotationAssertion( "liver neoplasm") AnnotationAssertion( "neoplastic liver") -AnnotationAssertion( "HCC") -AnnotationAssertion( "malignant hepatoma") AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "hepatocellular carcinoma") +AnnotationAssertion( "HCC") +AnnotationAssertion( "malignant hepatoma") AnnotationAssertion( "MP:0003331") AnnotationAssertion(rdfs:label "increased hepatocellular carcinoma incidence") SubClassOf( ) @@ -48539,8 +48539,8 @@ SubClassOf( (increased ovarian carcinoma incidence) AnnotationAssertion(Annotation( "NCBI:matt") "greater than the expected number of a malignant neoplasm arising from ovarian tissue, occurring in a specific population in a given time period") -AnnotationAssertion( "ovarian carcinoma") AnnotationAssertion( "MPheno.ontology") +AnnotationAssertion( "ovarian carcinoma") AnnotationAssertion( "MP:0003579") AnnotationAssertion(rdfs:label "increased ovarian carcinoma incidence") SubClassOf( ) @@ -48769,8 +48769,8 @@ SubClassOf( (increased renal hamartoma incidence) AnnotationAssertion(Annotation( "NCBI:matt") "greater than the expected number of a benign formation of a mass of tissue of disproportionate size and distribution in the kidney, occurring in a specific population in a given time period; hamartomas are typically composed of an overgrowth of mature cells and tissues that normally occur in this tissue") -AnnotationAssertion( "renal hamartoma") AnnotationAssertion( "MPheno.ontology") +AnnotationAssertion( "renal hamartoma") AnnotationAssertion( "MP:0003602") AnnotationAssertion(rdfs:label "increased renal hamartoma incidence") EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( )))) @@ -48780,10 +48780,10 @@ SubClassOf( (increased renal hemangioblastoma incidence) AnnotationAssertion(Annotation( "NCBI:matt") "greater than the expected number of a benign cyst-like tumor of the kidney that is composed of multiple capillary and sinusoidal channels lined with endothelial cells, occurring in a specific population in a given time period") -AnnotationAssertion( "renal haemangioblastoma") -AnnotationAssertion( "renal hemangioblastoma") AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "increased renal haemangioblastoma incidence") +AnnotationAssertion( "renal haemangioblastoma") +AnnotationAssertion( "renal hemangioblastoma") AnnotationAssertion( "MP:0003603") AnnotationAssertion(rdfs:label "increased renal hemangioblastoma incidence") EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( )))) @@ -53948,10 +53948,10 @@ SubClassOf( "MGI:monikat") "cardiovascular structural anomaly in which the aorta arises from the right ventricle while the pulmonary artery arises from the left ventricle") AnnotationAssertion( "MP:0006127") +AnnotationAssertion( "transposition of great vessels") AnnotationAssertion( "TGA") AnnotationAssertion( "discordant VA connections") AnnotationAssertion( "MPheno.ontology") -AnnotationAssertion( "transposition of great vessels") AnnotationAssertion( "MP:0004110") AnnotationAssertion( ) AnnotationAssertion(rdfs:label "transposition of great arteries") @@ -54964,9 +54964,9 @@ SubClassOf( (increased squamous cell carcinoma incidence) AnnotationAssertion(Annotation( "MGI:rbabiuk") "higher than normal incidence of a carcinoma that arises from stratified squamous epithelium that occurs in sites where glandular or columnar epithelium is normally present, such as the skin, esophagus, lungs and cervix") -AnnotationAssertion( "SCC") AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "squamous cell carcinoma") +AnnotationAssertion( "SCC") AnnotationAssertion( "MP:0004207") AnnotationAssertion(rdfs:label "increased squamous cell carcinoma incidence") SubClassOf( ) @@ -57732,8 +57732,8 @@ SubClassOf( (increased testicular teratoma incidence) AnnotationAssertion(Annotation( "MGI:llw2") "greater than the expected number of a usually benign tumor found in the testis that is the result of an anomaly of germ cell development, occurring in a specific population in a given time period; teratomas typically contains a diversity of tissues often representing all organ systems such as hair, teeth, bone, thyroid, or nerve tissue") -AnnotationAssertion( "testicular teratoma") AnnotationAssertion( "MPheno.ontology") +AnnotationAssertion( "testicular teratoma") AnnotationAssertion( "MP:0004478") AnnotationAssertion(rdfs:label "increased testicular teratoma incidence") EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( )))) @@ -61909,8 +61909,8 @@ SubClassOf( (increased endometrial carcinoma incidence) AnnotationAssertion(Annotation( "RGD:cur") "greater than the expected number of a malignant neoplasm arising from the endometrial tissue, occurring in a specific population in a given time period") -AnnotationAssertion( "endometrial carcinoma") AnnotationAssertion( "MPheno.ontology") +AnnotationAssertion( "endometrial carcinoma") AnnotationAssertion( "MP:0004868") AnnotationAssertion(rdfs:label "increased endometrial carcinoma incidence") SubClassOf( ) @@ -67148,11 +67148,11 @@ SubClassOf( (small cranium) AnnotationAssertion(Annotation( "MGI:cwg") "reduced size of the cranium") +AnnotationAssertion( "decreased skull size") +AnnotationAssertion( "reduced skull size") AnnotationAssertion( "decreased cranium size") AnnotationAssertion( "reduced cranium size") AnnotationAssertion( "MPheno.ontology") -AnnotationAssertion( "decreased skull size") -AnnotationAssertion( "reduced skull size") AnnotationAssertion( "MP:0005352") AnnotationAssertion(rdfs:label "small cranium") SubClassOf( ) @@ -68401,17 +68401,17 @@ SubClassOf( (increased chronic myelocytic leukemia incidence) AnnotationAssertion(Annotation( "ISBN:0-683-40008-8") "higher than normal incidence of a heterogeneous group of myeloproliferative disorders that may evolve into acute leukemia in late stages") -AnnotationAssertion( "CML") -AnnotationAssertion( "chronic granulocytic leukaemia") -AnnotationAssertion( "chronic granulocytic leukemia") -AnnotationAssertion( "chronic myelocytic leukaemia") -AnnotationAssertion( "chronic myelocytic leukemia") -AnnotationAssertion( "chronic myelogenous leukaemia") -AnnotationAssertion( "chronic myelogenous leukemia") -AnnotationAssertion( "chronic myeloid leukaemia") -AnnotationAssertion( "chronic myeloid leukemia") AnnotationAssertion( "increased chronic myelocytic leukaemia incidence") AnnotationAssertion( "MPheno.ontology") +AnnotationAssertion( "CML") +AnnotationAssertion( "chronic granulocytic leukaemia") +AnnotationAssertion( "chronic granulocytic leukemia") +AnnotationAssertion( "chronic myelocytic leukaemia") +AnnotationAssertion( "chronic myelocytic leukemia") +AnnotationAssertion( "chronic myelogenous leukaemia") +AnnotationAssertion( "chronic myelogenous leukemia") +AnnotationAssertion( "chronic myeloid leukaemia") +AnnotationAssertion( "chronic myeloid leukemia") AnnotationAssertion( "MP:0005481") AnnotationAssertion(rdfs:label "increased chronic myelocytic leukemia incidence") SubClassOf( ) @@ -70185,10 +70185,10 @@ SubClassOf( (increased spleen neoplasm incidence) AnnotationAssertion(Annotation( "MGI:csmith") "greater than the expected number of a neoplasm of the spleen, occurring in a specific population in a given time period") -AnnotationAssertion( "neoplastic spleen") -AnnotationAssertion( "spleen neoplasia") AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "spleen neoplasm") +AnnotationAssertion( "neoplastic spleen") +AnnotationAssertion( "spleen neoplasia") AnnotationAssertion( "MP:0005649") AnnotationAssertion(rdfs:label "increased spleen neoplasm incidence") EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( )))) @@ -72196,11 +72196,11 @@ SubClassOf( "MGI:smb") Annotation( "NCBI:matt") "greater than the expected number of abnormal rapidly proliferating cells in the eyelid, usually in the form of a distinct mass, occurring in a specific population in a given time period") AnnotationAssertion( "increased eyelid tumour incidence") -AnnotationAssertion( "tumor of the eyelid") -AnnotationAssertion( "tumour of the eyelid") AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "eyelid tumor") AnnotationAssertion( "eyelid tumour") +AnnotationAssertion( "tumor of the eyelid") +AnnotationAssertion( "tumour of the eyelid") AnnotationAssertion( "MP:0006169") AnnotationAssertion(rdfs:label "increased eyelid tumor incidence") EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( )))) @@ -72295,10 +72295,10 @@ AnnotationAssertion(Annotation( "increased retina haemangioma incidence") AnnotationAssertion( "increased retinal haemangioma incidence") AnnotationAssertion( "increased retinal hemangioma incidence") -AnnotationAssertion( "retinal angioma") AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "retinal haemangioma") AnnotationAssertion( "retinal hemangioma") +AnnotationAssertion( "retinal angioma") AnnotationAssertion( "MP:0006182") AnnotationAssertion(rdfs:label "increased retina hemangioma incidence") EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( )))) @@ -73257,10 +73257,10 @@ SubClassOf( (increased medulloblastoma incidence) AnnotationAssertion(Annotation( "MGI:rbabiuk") Annotation( "MGI:smb") "greater than the expected number of a solid, cancerous tumor originating in the cerebellum of the brain and of primitive neuroectodermal origin, occurring in a specific population in a given time period") -AnnotationAssertion( "primitive neuroendocrine tumor") -AnnotationAssertion( "primitive neuroendocrine tumour") AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "medulloblastoma") +AnnotationAssertion( "primitive neuroendocrine tumor") +AnnotationAssertion( "primitive neuroendocrine tumour") AnnotationAssertion( "MP:0006283") AnnotationAssertion(rdfs:label "increased medulloblastoma incidence") EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )))) @@ -74574,8 +74574,8 @@ SubClassOf( (increased mammary adenoacanthoma incidence) AnnotationAssertion(Annotation( "ISBN:0-8036-0655-9") Annotation( "MGI:rbabiuk") Annotation( "MGI:smb") "higher than normal incidence of malignant tumors in which some cells have undergone squamous metaplasia in the mammary gland") -AnnotationAssertion( "mammary adenoacanthoma") AnnotationAssertion( "MPheno.ontology") +AnnotationAssertion( "mammary adenoacanthoma") AnnotationAssertion( "MP:0006422") AnnotationAssertion(rdfs:label "increased mammary adenoacanthoma incidence") SubClassOf( ) @@ -74695,9 +74695,9 @@ AnnotationAssertion(Annotation( "increased ovarian tumor incidence") AnnotationAssertion( "increased ovarian tumour incidence") AnnotationAssertion( "increased ovary tumour incidence") -AnnotationAssertion( "ovarian tumor") -AnnotationAssertion( "ovarian tumour") AnnotationAssertion( "MPheno.ontology") +AnnotationAssertion( "ovarian tumor") +AnnotationAssertion( "ovarian tumour") AnnotationAssertion( "MP:0008000") AnnotationAssertion(rdfs:label "increased ovary tumor incidence") EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( )))) @@ -74793,9 +74793,9 @@ SubClassOf( (increased gastric adenocarcinoma incidence) AnnotationAssertion(Annotation( "MGI:llw2") "higher than normal incidence of a malignant neoplasm of epithelial cells in the stomach") -AnnotationAssertion( "stomach adenocarcinoma") AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "gastric adenocarcinoma") +AnnotationAssertion( "stomach adenocarcinoma") AnnotationAssertion( "MP:0008010") AnnotationAssertion(rdfs:label "increased gastric adenocarcinoma incidence") EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( )))) @@ -83977,8 +83977,8 @@ SubClassOf( (increased lung carcinoma incidence) AnnotationAssertion(Annotation( "ISBN:0-683-40008-8") Annotation( "MGI:csmith") "greater than the expected number of a malignant neoplasm of the lung, arising from epithelial cells, usually glandular or squamous, occurring in a specific population in a given time period") -AnnotationAssertion( "lung carcinoma") AnnotationAssertion( "MPheno.ontology") +AnnotationAssertion( "lung carcinoma") AnnotationAssertion( "MP:0008714") AnnotationAssertion(rdfs:label "increased lung carcinoma incidence") EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( )))) @@ -83998,8 +83998,8 @@ SubClassOf( ObjectSomeValuesFrom( (increased lung non-small cell carcinoma incidence) AnnotationAssertion(Annotation( "MESH:C04.557.470.200.300") "greater than the expected number of a heterogeneous aggregate of at least three distinct histological types of lung cancer, occurring in a specific population in a given time period") -AnnotationAssertion( "lung non-small cell carcinoma") AnnotationAssertion( "MPheno.ontology") +AnnotationAssertion( "lung non-small cell carcinoma") AnnotationAssertion( "MP:0008716") AnnotationAssertion(rdfs:label "increased lung non-small cell carcinoma incidence") SubClassOf( ) @@ -84008,9 +84008,9 @@ SubClassOf( ObjectSomeValuesFrom( (increased lung squamous cell carcinoma incidence) AnnotationAssertion(Annotation( "MGI:csmith") "greater than the expected number of a lung carcinoma derived from stratified squamous epithelium, occurring in a specific population in a given time period") -AnnotationAssertion( "lung SCC") AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "lung squamous cell carcinoma") +AnnotationAssertion( "lung SCC") AnnotationAssertion( "MP:0008717") AnnotationAssertion(rdfs:label "increased lung squamous cell carcinoma incidence") SubClassOf( ) @@ -84716,12 +84716,11 @@ SubClassOf( (increased pancreatic acinar cell carcinoma incidence) AnnotationAssertion(Annotation( "MGI:csmith") "greater than the expected number of an adenocarcinoma arising from cells of the pancreas that secrete digestive enzymes, occurring in a specific population in a given time period") -AnnotationAssertion( "pancreatic tumor") AnnotationAssertion( "increased pancreatic acinar cell adenocarcinoma incidence") -AnnotationAssertion( "pancreatic ACC") -AnnotationAssertion( "pancreatic acinar carcinoma") AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "acinar carcinoma") +AnnotationAssertion( "pancreatic ACC") +AnnotationAssertion( "pancreatic acinar carcinoma") AnnotationAssertion( "MP:0008780") AnnotationAssertion(rdfs:label "increased pancreatic acinar cell carcinoma incidence") SubClassOf( ) @@ -87626,8 +87625,8 @@ SubClassOf( (increased pancreas adenoma incidence) AnnotationAssertion(Annotation( "MGI:csmith") "greater than the expected number of a benign epithelial neoplasm with a glandular organization arising in the pancreas, occurring in a specific population in a given time period") -AnnotationAssertion( "pancreatic adenoma") AnnotationAssertion( "MPheno.ontology") +AnnotationAssertion( "pancreatic adenoma") AnnotationAssertion( "MP:0009043") AnnotationAssertion(rdfs:label "increased pancreas adenoma incidence") SubClassOf( ) @@ -87636,8 +87635,8 @@ SubClassOf( (increased adrenal gland adenoma incidence) AnnotationAssertion(Annotation( "MGI:csmith") "greater than the expected number of a benign epithelial neoplasm with a glandular organization arising in the adrenal gland, occurring in a specific population in a given time period") -AnnotationAssertion( "adrenal adenoma") AnnotationAssertion( "MPheno.ontology") +AnnotationAssertion( "adrenal adenoma") AnnotationAssertion( "MP:0009044") AnnotationAssertion(rdfs:label "increased adrenal gland adenoma incidence") SubClassOf( ) @@ -88993,10 +88992,10 @@ SubClassOf( ObjectSomeValuesFrom( (increased pancreatic ductal adenocarcinoma incidence) AnnotationAssertion(Annotation( "MESH:C04.557.470.200.025.232.750") "greater than the expected number of an adenocarcinoma that arises from the pancreatic ducts, occurring in a specific population in a given time period") -AnnotationAssertion( "PDAC") -AnnotationAssertion( "pancreatic duct cell carcinoma") AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "pancreatic ductal adenocarcinoma") +AnnotationAssertion( "PDAC") +AnnotationAssertion( "pancreatic duct cell carcinoma") AnnotationAssertion( "MP:0009151") AnnotationAssertion(rdfs:label "increased pancreatic ductal adenocarcinoma incidence") SubClassOf( ) @@ -89005,9 +89004,9 @@ SubClassOf( (increased pancreatic intraepithelial neoplasia incidence) AnnotationAssertion(Annotation( "PMID:11342768") "greater than the expected number of noninvasive pancreatic duct lesions that affect smaller caliber ducts and do not involve the main pancreatic duct, occurring in a specific population in a given time period") -AnnotationAssertion( "PanIN") AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "pancreatic intraepithelial neoplasia") +AnnotationAssertion( "PanIN") AnnotationAssertion( "MP:0009152") AnnotationAssertion(rdfs:label "increased pancreatic intraepithelial neoplasia incidence") SubClassOf( ) @@ -89016,13 +89015,13 @@ SubClassOf( "MGI:csmith") "greater than the expected number of neoplams in the pancreas occurring in a specific population in a given time period") AnnotationAssertion( "increased pancreas tumour incidence") -AnnotationAssertion( "pancreas cancer") -AnnotationAssertion( "pancreas neoplasms") -AnnotationAssertion( "pancreatic cancer") -AnnotationAssertion( "pancreatic neoplasms") -AnnotationAssertion( "pancreatic tumor") -AnnotationAssertion( "pancreatic tumour") AnnotationAssertion( "MPheno.ontology") +AnnotationAssertion( "pancreas cancer") +AnnotationAssertion( "pancreas neoplasms") +AnnotationAssertion( "pancreatic cancer") +AnnotationAssertion( "pancreatic neoplasms") +AnnotationAssertion( "pancreatic tumor") +AnnotationAssertion( "pancreatic tumour") AnnotationAssertion( "MP:0009153") AnnotationAssertion(rdfs:label "increased pancreas tumor incidence") EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( )))) @@ -89826,11 +89825,11 @@ SubClassOf( (increased prostate intraepithelial neoplasia incidence) AnnotationAssertion(Annotation( "MGI:csmith") "higher than normal incidence of a non-invasive neoplastic proliferation of the epithelial cells that line the acini and the ducts of the prostate gland") -AnnotationAssertion( "PIN") -AnnotationAssertion( "prostatic intraepithelial neoplasia") AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "prostate intra-epithelial neoplasia") AnnotationAssertion( "prostate intraepithelial neoplasia") +AnnotationAssertion( "PIN") +AnnotationAssertion( "prostatic intraepithelial neoplasia") AnnotationAssertion( "MP:0009219") AnnotationAssertion(rdfs:label "increased prostate intraepithelial neoplasia incidence") SubClassOf( ) @@ -89838,9 +89837,9 @@ SubClassOf( (increased prostate gland adenocarcinoma incidence) AnnotationAssertion(Annotation( "MGI:csmith") "higher than normal incidence of a malignant neoplasm arising from prostate tissue") -AnnotationAssertion( "prostate adenocarcinoma") AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "prostate gland adenocarcinoma") +AnnotationAssertion( "prostate adenocarcinoma") AnnotationAssertion( "MP:0009220") AnnotationAssertion(rdfs:label "increased prostate gland adenocarcinoma incidence") SubClassOf( ) @@ -89868,12 +89867,12 @@ SubClassOf( ObjectSomeValuesFrom( "MGI:anna") "greater than the expected number of abnormal rapidly proliferating cells in the uterus, usually in the form of a distinct mass, occurring in a specific population in a given time period") AnnotationAssertion( "increased uterus tumour incidence") -AnnotationAssertion( "uterine mass") -AnnotationAssertion( "uterine tumor") -AnnotationAssertion( "uterine tumour") -AnnotationAssertion( "uterus tumor") -AnnotationAssertion( "uterus tumour") AnnotationAssertion( "MPheno.ontology") +AnnotationAssertion( "uterine mass") +AnnotationAssertion( "uterine tumor") +AnnotationAssertion( "uterine tumour") +AnnotationAssertion( "uterus tumor") +AnnotationAssertion( "uterus tumour") AnnotationAssertion( "MP:0009222") AnnotationAssertion(rdfs:label "increased uterus tumor incidence") EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( )))) @@ -90855,9 +90854,9 @@ SubClassOf( (increased small intestine adenocarcinoma incidence) AnnotationAssertion(Annotation( "MGI:anna") "higher than normal incidence of a malignant neoplasm of epithelial cells in the small intestine") -AnnotationAssertion( "small intestinal adenocarcinoma") AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "small intestine adenocarcinoma") +AnnotationAssertion( "small intestinal adenocarcinoma") AnnotationAssertion( "MP:0009309") AnnotationAssertion(rdfs:label "increased small intestine adenocarcinoma incidence") SubClassOf( ) @@ -90866,9 +90865,9 @@ SubClassOf( ObjectSomeValuesFrom( (increased large intestine adenocarcinoma incidence) AnnotationAssertion(Annotation( "MGI:anna") "higher than normal incidence of a malignant neoplasm of epithelial cells in the large intestine") -AnnotationAssertion( "large intestinal adenocarcinoma") AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "large intestine adenocarcinoma") +AnnotationAssertion( "large intestinal adenocarcinoma") AnnotationAssertion( "MP:0009310") AnnotationAssertion(rdfs:label "increased large intestine adenocarcinoma incidence") SubClassOf( ) @@ -90877,9 +90876,9 @@ SubClassOf( ObjectSomeValuesFrom( (increased duodenum adenocarcinoma incidence) AnnotationAssertion(Annotation( "MGI:anna") "higher than normal incidence of a malignant neoplasm of epithelial cells in the duodenum") -AnnotationAssertion( "duodenal adenocarcinoma") AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "duodenum adenocarcinoma") +AnnotationAssertion( "duodenal adenocarcinoma") AnnotationAssertion( "MP:0009311") AnnotationAssertion(rdfs:label "increased duodenum adenocarcinoma incidence") SubClassOf( ) @@ -90908,9 +90907,9 @@ SubClassOf( ObjectSomeValuesFrom( (increased colon adenocarcinoma incidence) AnnotationAssertion(Annotation( "MGI:anna") "higher than normal incidence of a malignant neoplasm of epithelial cells in the colon") -AnnotationAssertion( "colonic adenocarcinoma") AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "colon adenocarcinoma") +AnnotationAssertion( "colonic adenocarcinoma") AnnotationAssertion( "MP:0009314") AnnotationAssertion(rdfs:label "increased colon adenocarcinoma incidence") SubClassOf( ) @@ -90919,9 +90918,9 @@ SubClassOf( ObjectSomeValuesFrom( (increased rectum adenocarcinoma incidence) AnnotationAssertion(Annotation( "MGI:anna") "higher than normal incidence of a malignant neoplasm of epithelial cells in the rectum") -AnnotationAssertion( "rectal adenocarcinoma") AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "rectum adenocarcinoma") +AnnotationAssertion( "rectal adenocarcinoma") AnnotationAssertion( "MP:0009315") AnnotationAssertion(rdfs:label "increased rectum adenocarcinoma incidence") SubClassOf( ) @@ -90930,9 +90929,9 @@ SubClassOf( ObjectSomeValuesFrom( (increased anal adenocarcinoma incidence) AnnotationAssertion(Annotation( "MGI:anna") "higher than normal incidence of a malignant neoplasm of epithelial cells in the anal canal") -AnnotationAssertion( "anal canal adenocarcinoma") AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "anal adenocarcinoma") +AnnotationAssertion( "anal canal adenocarcinoma") AnnotationAssertion( "MP:0009316") AnnotationAssertion(rdfs:label "increased anal adenocarcinoma incidence") SubClassOf( ) @@ -90941,10 +90940,10 @@ SubClassOf( ObjectSomeValuesFrom( (increased follicular lymphoma incidence) AnnotationAssertion(Annotation( "ISBN:0-683-40008-8") "higher than normal incidence of malignant lymphoma arising from lymphoid follicular B cells which may be small or large") -AnnotationAssertion( "giant follicular lymphoblastoma") -AnnotationAssertion( "nodular lymphoma") AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "follicular lymphoma") +AnnotationAssertion( "giant follicular lymphoblastoma") +AnnotationAssertion( "nodular lymphoma") AnnotationAssertion( "MP:0009317") AnnotationAssertion(rdfs:label "increased follicular lymphoma incidence") SubClassOf( ) @@ -90961,9 +90960,9 @@ SubClassOf( (increased small lymphocytic lymphoma incidence) AnnotationAssertion(Annotation( "ISBN:0-683-40008-8") "higher than normal incidence of lymphocytic leukemia where the lymphocytes are not increased in the peripheral blood, but lymph nodes are enlarged and other lymphoid tissue or bone marrow is infiltrated by small lymphocytes") -AnnotationAssertion( "well-differentiated lymphocytic lymphoma") AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "small lymphocytic lymphoma") +AnnotationAssertion( "well-differentiated lymphocytic lymphoma") AnnotationAssertion( "MP:0009319") AnnotationAssertion(rdfs:label "increased small lymphocytic lymphoma incidence") SubClassOf( ) @@ -90971,9 +90970,9 @@ SubClassOf( (increased lymphoblastic lymphoma incidence) AnnotationAssertion(Annotation( "ISBN:0-683-40008-8") "higher than normal incidence of diffuse lymphoma with supradiaphragmatic distribution and T lymphocytes having convoluted nuclei") -AnnotationAssertion( "lymphoblastoma") AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "lymphoblastic lymphoma") +AnnotationAssertion( "lymphoblastoma") AnnotationAssertion( "MP:0009320") AnnotationAssertion(rdfs:label "increased lymphoblastic lymphoma incidence") SubClassOf( ) @@ -92237,24 +92236,24 @@ SubClassOf( (increased myeloid sarcoma incidence) AnnotationAssertion(Annotation( "ISBN:0-683-40008-8") "higher than normal incidence of a malignant tumor of immature myeloid cells, often associated with or preceeding granulocytic leukemia") -AnnotationAssertion( "EMMT") -AnnotationAssertion( "extramedullary myeloid tumors") -AnnotationAssertion( "extramedullary myeloid tumours") -AnnotationAssertion( "granulocytic sarcoma") AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "myeloid sarcoma") +AnnotationAssertion( "EMMT") +AnnotationAssertion( "extramedullary myeloid tumors") +AnnotationAssertion( "extramedullary myeloid tumours") +AnnotationAssertion( "granulocytic sarcoma") AnnotationAssertion( "MP:0009439") AnnotationAssertion(rdfs:label "increased myeloid sarcoma incidence") -SubClassOf( ) SubClassOf( ) +SubClassOf( ) # Class: (increased myeloma incidence) AnnotationAssertion(Annotation( "DOID:0070004") Annotation( "ISBN:0-683-40008-8") "higher than normal incidence of a bone marrow cancer in which abnormal plasma cells multiply uncontrollably in the bone marrow and occasionally in other parts of the body") -AnnotationAssertion( "plasma cell tumor") -AnnotationAssertion( "plasma cell tumour") AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "myeloma") +AnnotationAssertion( "plasma cell tumor") +AnnotationAssertion( "plasma cell tumour") AnnotationAssertion( "MP:0009440") AnnotationAssertion(rdfs:label "increased myeloma incidence") SubClassOf( ) @@ -92271,9 +92270,9 @@ SubClassOf( (increased ovarian teratoma incidence) AnnotationAssertion(Annotation( "MGI:llw2") "greater than the expected number of a usually benign tumor found in the ovary, occurring in a specific population in a given time period; ovarian teratomas are typically the result of an anomaly of oogenesis and typically contains a diversity of tissues often representing all organ systems e.g. hair, teeth, bone, thyroid, nerve tissue") -AnnotationAssertion( "ovarian dermoid cyst") AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "ovarian teratoma") +AnnotationAssertion( "ovarian dermoid cyst") AnnotationAssertion( "MP:0009442") AnnotationAssertion(rdfs:label "increased ovarian teratoma incidence") SubClassOf( ) @@ -92554,8 +92553,8 @@ SubClassOf( (increased skin hamartoma incidence) AnnotationAssertion(Annotation( "MGI:llw2") "greater than the expected number of a benign formation of a mass of tissue of disproportionate size and distribution in the skin, but composed of an overgrowth of mature cells and tissues that normally occur in this tissue, occurring in a specific population in a given time period") -AnnotationAssertion( "skin hamartoma") AnnotationAssertion( "MPheno.ontology") +AnnotationAssertion( "skin hamartoma") AnnotationAssertion( "MP:0009469") AnnotationAssertion(rdfs:label "increased skin hamartoma incidence") EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( )))) @@ -92973,9 +92972,9 @@ SubClassOf( (increased mammary gland ductal carcinoma incidence) AnnotationAssertion(Annotation( "MGI:csmith") "higher than normal incidence of malignant tumors of the ducts of the mammary gland") -AnnotationAssertion( "ductal carcinoma in situ") -AnnotationAssertion( "mammary gland ductal carcinoma") AnnotationAssertion( "MPheno.ontology") +AnnotationAssertion( "ductal carcinoma in situ") +AnnotationAssertion( "mammary gland ductal carcinoma") AnnotationAssertion( "MP:0009508") AnnotationAssertion(rdfs:label "increased mammary gland ductal carcinoma incidence") SubClassOf( ) @@ -93034,11 +93033,11 @@ SubClassOf( (increased gastrointestinal stromal tumor incidence) AnnotationAssertion(Annotation( "MGI:anna") Annotation( "OMIM:606764") Annotation( "http://en.wikipedia.org/wiki/Gastrointestinal_stromal_tumor") "higher than normal incidence of non-epithelial, mesenchymal tumors of the gastrointestinal tract, thought to originate from the interstitial cells of Cajal, the pacemaker cells that regulate peristalsis in the digestive tract; approximately 70% of GISTs develop in the stomach, 20% in the small intestine, and less than 10% in the esophagus, colon, and rectum; GISTs are tumors of connective tissue, i.e. sarcomas, account for 1-3% of all gastrointestinal malignancies in human, and are typically more cellular than other gastrointestinal sarcomas") -AnnotationAssertion( "GISTs") AnnotationAssertion( "increased gastrointestinal stromal tumour incidence") AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "gastrointestinal stromal tumor") AnnotationAssertion( "gastrointestinal stromal tumour") +AnnotationAssertion( "GISTs") AnnotationAssertion( "MP:0009515") AnnotationAssertion(rdfs:label "increased gastrointestinal stromal tumor incidence") SubClassOf( ) @@ -93448,8 +93447,8 @@ SubClassOf( (increased urinary bladder carcinoma incidence) AnnotationAssertion(Annotation( "MGI:anna") "greater than the expected number of a malignant neoplasm of the urinary bladder, arising from epithelial cells, occurring in a specific population in a given time period") -AnnotationAssertion( "urinary bladder carcinoma") AnnotationAssertion( "MPheno.ontology") +AnnotationAssertion( "urinary bladder carcinoma") AnnotationAssertion( "MP:0009550") AnnotationAssertion(rdfs:label "increased urinary bladder carcinoma incidence") SubClassOf( ) @@ -93458,8 +93457,8 @@ SubClassOf( (increased urinary bladder transitional cell carcinoma incidence) AnnotationAssertion(Annotation( "MGI:anna") "greater than the expected number of a malignant neoplasm of the transitional epithelial layer of the urinary bladder, occurring in a specific population in a given time period") -AnnotationAssertion( "urinary bladder transitional cell carcinoma") AnnotationAssertion( "MPheno.ontology") +AnnotationAssertion( "urinary bladder transitional cell carcinoma") AnnotationAssertion( "MP:0009551") AnnotationAssertion(rdfs:label "increased urinary bladder transitional cell carcinoma incidence") SubClassOf( ) @@ -93868,9 +93867,9 @@ SubClassOf( (increased liver adenocarcinoma incidence) AnnotationAssertion(Annotation( "MGI:anna") "greater than the expected number of a malignant neoplasm of epithelial cells in the liver, occurring in a specific population in a given time period") -AnnotationAssertion( "hepatic adenocarcinoma") AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "liver adenocarcinoma") +AnnotationAssertion( "hepatic adenocarcinoma") AnnotationAssertion( "MP:0009591") AnnotationAssertion(rdfs:label "increased liver adenocarcinoma incidence") SubClassOf( ) @@ -93880,11 +93879,11 @@ SubClassOf( "MGI:anna") "greater than the expected number of rare testicular tumors of the male gonadal interstitium, occurring in a specific population in a given time period; Leydig cell tumors are frequently hormonally active, leading to feminizing or virilizing syndromes; Leydig cell tumors comprise 1-3% of all testicular neoplasms, can be pure or mixed with other sex cord-stromal or germ cell tumors, and are usually benign, although malignant variants also occur") AnnotationAssertion( "increased Leydig cell tumour incidence") -AnnotationAssertion( "interstitial cell tumor of testis") -AnnotationAssertion( "interstitial cell tumour of testis") AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "Leydig cell tumor") AnnotationAssertion( "Leydig cell tumour") +AnnotationAssertion( "interstitial cell tumor of testis") +AnnotationAssertion( "interstitial cell tumour of testis") AnnotationAssertion( "MP:0009592") AnnotationAssertion(rdfs:label "increased Leydig cell tumor incidence") SubClassOf( ) @@ -95017,8 +95016,8 @@ SubClassOf( (increased skin squamous cell carcinoma incidence) AnnotationAssertion(Annotation( "MGI:csmith") "greater than the expected number of a skin carcinoma derived from stratified squamous epithelium, occurring in a specific population in a given time period") -AnnotationAssertion( "skin squamous cell carcinoma") AnnotationAssertion( "MPheno.ontology") +AnnotationAssertion( "skin squamous cell carcinoma") AnnotationAssertion( "MP:0009704") AnnotationAssertion(rdfs:label "increased skin squamous cell carcinoma incidence") SubClassOf( ) @@ -99332,10 +99331,10 @@ AnnotationAssertion(Annotation( ) AnnotationAssertion( "csmith") AnnotationAssertion( "2010-03-03T03:22:41Z") -AnnotationAssertion( "hepatic blastoma") -AnnotationAssertion( "liver blastoma") AnnotationAssertion( "MPheno.ontology") AnnotationAssertion( "hepatoblastoma") +AnnotationAssertion( "hepatic blastoma") +AnnotationAssertion( "liver blastoma") AnnotationAssertion( "MP:0010054") AnnotationAssertion(rdfs:label "increased hepatoblastoma incidence") EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )))) @@ -99713,8 +99712,8 @@ AnnotationAssertion(Annotation( ) AnnotationAssertion( "csmith") AnnotationAssertion( "2010-03-19T02:34:32Z") -AnnotationAssertion( "osteochondroma") AnnotationAssertion( "MPheno.ontology") +AnnotationAssertion( "osteochondroma") AnnotationAssertion( "MP:0010079") AnnotationAssertion(rdfs:label "increased osteochondroma incidence") SubClassOf( ) @@ -102573,8 +102572,8 @@ AnnotationAssertion( "2010-08-03T12:39:51Z") AnnotationAssertion( "MP:0005509") AnnotationAssertion( "increased tongue tumour incidence") -AnnotationAssertion( "tongue neoplasm") AnnotationAssertion( "MPheno.ontology") +AnnotationAssertion( "tongue neoplasm") AnnotationAssertion( "MP:0010272") AnnotationAssertion(rdfs:label "increased tongue tumor incidence") EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( )))) @@ -103484,9 +103483,9 @@ AnnotationAssertion(Annotation( ) AnnotationAssertion( "csmith") AnnotationAssertion( "2010-08-16T01:30:51Z") -AnnotationAssertion( "aggressive fibromatosis") -AnnotationAssertion( "musculo-aponeurotic fibromatosis") AnnotationAssertion( "MPheno.ontology") +AnnotationAssertion( "aggressive fibromatosis") +AnnotationAssertion( "musculo-aponeurotic fibromatosis") AnnotationAssertion( "MP:0010338") AnnotationAssertion(rdfs:label "increased desmoid tumor incidence") EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )))) @@ -103740,9 +103739,9 @@ AnnotationAssertion( "2010-08-17T12:47:29Z") AnnotationAssertion( "MP:0003831") AnnotationAssertion( "increased prostate gland tumour incidence") -AnnotationAssertion( "prostate tumor") -AnnotationAssertion( "prostate tumour") AnnotationAssertion( "MPheno.ontology") +AnnotationAssertion( "prostate tumor") +AnnotationAssertion( "prostate tumour") AnnotationAssertion( "MP:0010357") AnnotationAssertion(rdfs:label "increased prostate gland tumor incidence") EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( )))) @@ -132915,9 +132914,9 @@ AnnotationAssertion( "2013-12-04T15:36:28Z") AnnotationAssertion( "MP:0002022") AnnotationAssertion( "increased lymphsarcoma incidence") -AnnotationAssertion( "lymphoid tumor") -AnnotationAssertion( "lymphoid tumour") AnnotationAssertion( "MPheno.ontology") +AnnotationAssertion( "lymphoid tumor") +AnnotationAssertion( "lymphoid tumour") AnnotationAssertion( "MP:0012431") AnnotationAssertion(rdfs:label "increased lymphoma incidence") EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ) ObjectSomeValuesFrom( )))) @@ -142297,9 +142296,9 @@ AnnotationAssertion(Annotation( "increased pineal body tumor incidence") AnnotationAssertion( "increased pineal body tumour incidence") AnnotationAssertion( "increased pineal gland tumour incidence") -AnnotationAssertion( "pineal tumor") -AnnotationAssertion( "pineal tumour") -AnnotationAssertion( "pinealoma") +AnnotationAssertion( "pineal tumor") +AnnotationAssertion( "pineal tumour") +AnnotationAssertion( "pinealoma") AnnotationAssertion( "MP:0013365") AnnotationAssertion(rdfs:label "increased pineal gland tumor incidence") EquivalentClasses( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ObjectIntersectionOf( ObjectSomeValuesFrom( ))) ObjectSomeValuesFrom( )))) @@ -142483,7 +142482,7 @@ SubClassOf( (increased sebaceous gland adenoma incidence) AnnotationAssertion(Annotation( "MGI:anna") "greater than the expected number of a benign epithelial neoplasm with a glandular organization arising in any sebaceous gland, occurring in a specific population in a given time period") -AnnotationAssertion( "sebaceous adenoma") +AnnotationAssertion( "sebaceous adenoma") AnnotationAssertion( "MP:0013383") AnnotationAssertion(rdfs:label "increased sebaceous gland adenoma incidence") SubClassOf( ) @@ -143938,7 +143937,7 @@ SubClassOf( (increased salivary gland adenoma incidence) AnnotationAssertion(Annotation( "MGI:anna") "greater than the expected number of a benign epithelial neoplasm with a glandular organization arising in any salivary gland, occurring in a specific population in a given time period") -AnnotationAssertion( "salivary adenoma") +AnnotationAssertion( "salivary adenoma") AnnotationAssertion( "MP:0013537") AnnotationAssertion(rdfs:label "increased salivary gland adenoma incidence") SubClassOf( ) @@ -143948,7 +143947,7 @@ SubClassOf( ObjectSomeValuesFrom( (increased Harderian gland adenoma incidence) AnnotationAssertion(Annotation( "MGI:anna") "greater than the expected number of a benign epithelial neoplasm with a glandular organization arising in the Harderian gland, occurring in a specific population in a given time period") -AnnotationAssertion( "Harderian gland adenoma") +AnnotationAssertion( "Harderian gland adenoma") AnnotationAssertion( "MP:0013538") AnnotationAssertion(rdfs:label "increased Harderian gland adenoma incidence") SubClassOf( ) @@ -143957,7 +143956,7 @@ SubClassOf( (increased ovary adenoma incidence) AnnotationAssertion(Annotation( "MGI:anna") "greater than the expected number of a benign epithelial neoplasm with a glandular organization arising in the ovary, occurring in a specific population in a given time period") -AnnotationAssertion( "ovarian adenoma") +AnnotationAssertion( "ovarian adenoma") AnnotationAssertion( "MP:0013539") AnnotationAssertion(rdfs:label "increased ovary adenoma incidence") SubClassOf( ) @@ -149549,7 +149548,7 @@ SubClassOf( (increased thymoma incidence) AnnotationAssertion(Annotation( "http://medical-dictionary.thefreedictionary.com/thymoma") Annotation( "http://www.cancer.gov/cancertopics/pdq/treatment/thymoma/patient/page1#_139") "greater than the expected number of a malignant neoplasm originating from the epithelial cells of the thymus, occurring in a specific population in a given time period; thymoma is an uncommon tumor linked with myasthenia gravis and other autoimmune diseases") -AnnotationAssertion( "thymoma") +AnnotationAssertion( "thymoma") AnnotationAssertion( "MP:0014127") AnnotationAssertion(rdfs:label "increased thymoma incidence") SubClassOf( ) @@ -149557,8 +149556,8 @@ SubClassOf( (increased Harderian gland adenocarcinoma incidence) AnnotationAssertion(Annotation( "ISBN:0080467717") "greater than the expected number of a malignant neoplasm of acinar epithelial cells in the Harderian gland, occurring in a specific population in a given time period; these usually are larger than adenomas and may cause facial selling and/or exophthalmos; they are highly cellular and disorganized compared to adenomas, with piling up of pleomorphic cells; areas of medullary or solid growth patterns are common; there may necrosis or hemorrhage, invasion beyond the orbit, and distant metastasis to the lungs, local lymph nodes, thymus or liver") -AnnotationAssertion( "Harderian adenocarcinoma") -AnnotationAssertion( "Harderian gland adenocarcinoma") +AnnotationAssertion( "Harderian adenocarcinoma") +AnnotationAssertion( "Harderian gland adenocarcinoma") AnnotationAssertion( "MP:0014128") AnnotationAssertion(rdfs:label "increased Harderian gland adenocarcinoma incidence") SubClassOf( ) @@ -165762,7 +165761,7 @@ SubClassOf( ObjectSomeValuesFrom( "HP:0000290") "any structural anomaly of the part of the face above the eyes; in human anatomy, the forehead is the fore part of the head, an area of the head bounded by three features, two of the skull and one of the scalp; the top of the forehead is marked by the hairline, the edge of the area where hair on the scalp grows while the bottom of the forehead is marked by the supraorbital ridge, the bone feature of the skull above the eyes; the two sides of the forehead are marked by the temporal ridge, a bone feature that links the supraorbital ridge to the coronal suture line and beyond") AnnotationAssertion( ) AnnotationAssertion( "2017-07-24T15:36:30Z"^^xsd:dateTime) -AnnotationAssertion( "abnormality of the frontal region of the face") +AnnotationAssertion( "abnormality of the frontal region of the face") AnnotationAssertion( "deformity of the forehead") AnnotationAssertion( "forehead anomaly") AnnotationAssertion( "malformation of the forehead") @@ -182938,8 +182937,8 @@ AnnotationAssertion(Annotation( ) AnnotationAssertion( "2021-09-27T09:16:42Z"^^xsd:dateTime) AnnotationAssertion( "fainting spell") +AnnotationAssertion( "fainting") AnnotationAssertion( "MPheno.ontology") -AnnotationAssertion( "fainting") AnnotationAssertion( "MP:0031302") AnnotationAssertion(rdfs:label "syncope") SubClassOf( )