But now I am facing a problem. We want to detected the novelty of the BGCs following this method.
" The novelty of BGCs, GCFs, and GCCs was determined by querying the 30,182 representative BGCs against a pre-processed BiG-FAM71 refer- ence database, using BiG-SliCE (version 1.1.0)32 with default para- meters. This reference database contains 1,225,071 BGCs from 209,206 publicly available microbial genomes, which integrates MIBiG v2.072, RefSeq complete/draft bacteria, GenBank fungi, Genbank archaea, and other MAGs from different studies. The reference database has gen- erated 29,955 GCF reference models. The rank first GCF of each query BGC with the calculated membership value ≤900 as used in BiG-FAM, was designated as the matched GCF. "
I am using the BIG-SLICE(version 1.1.1) to perform a query model to search my BGCs against the references database (the_full_result) . But I saw of the results and the report are convert to the SQLlite3. So how can I get the target data including the distance between my query and reference BGCs. And I also try to use the BIG-SLICE(version 2.0,0) to similar work , but the reference looks did not match
But now I am facing a problem. We want to detected the novelty of the BGCs following this method.
" The novelty of BGCs, GCFs, and GCCs was determined by querying the 30,182 representative BGCs against a pre-processed BiG-FAM71 refer- ence database, using BiG-SliCE (version 1.1.0)32 with default para- meters. This reference database contains 1,225,071 BGCs from 209,206 publicly available microbial genomes, which integrates MIBiG v2.072, RefSeq complete/draft bacteria, GenBank fungi, Genbank archaea, and other MAGs from different studies. The reference database has gen- erated 29,955 GCF reference models. The rank first GCF of each query BGC with the calculated membership value ≤900 as used in BiG-FAM, was designated as the matched GCF. "
I am using the BIG-SLICE(version 1.1.1) to perform a query model to search my BGCs against the references database (the_full_result) . But I saw of the results and the report are convert to the SQLlite3. So how can I get the target data including the distance between my query and reference BGCs. And I also try to use the BIG-SLICE(version 2.0,0) to similar work , but the reference looks did not match