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Add module for variancePartition #31

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vjmarteau opened this issue Jan 26, 2022 · 2 comments
Open

Add module for variancePartition #31

vjmarteau opened this issue Jan 26, 2022 · 2 comments

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@vjmarteau
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https://bioconductor.org/packages/variancePartition
@grst
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grst commented Jan 26, 2022

How does that relate to RUVSeq/SVA (#18)?

@vjmarteau
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If you add "batch" as factor you can nicely see how much variance is accounted for by batch effects. So far I have not only used the variancePartition package to check if batch effects have been removed after normalization (as suggested in #18), but also looked at the amount of variation that is explained by biological factors.

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@grst @vjmarteau