diff --git a/.kokoro/build.sh b/.kokoro/build.sh
index b625604b..2a2874e5 100755
--- a/.kokoro/build.sh
+++ b/.kokoro/build.sh
@@ -41,7 +41,7 @@ python3 -m pip install --upgrade --quiet nox
 python3 -m nox --version
 
 # If this is a continuous build, send the test log to the FlakyBot.
-# See https://github.com/googleapis/repo-automation-bots/tree/master/packages/flakybot.
+# See https://github.com/googleapis/repo-automation-bots/tree/main/packages/flakybot.
 if [[ $KOKORO_BUILD_ARTIFACTS_SUBDIR = *"continuous"* ]]; then
   cleanup() {
     chmod +x $KOKORO_GFILE_DIR/linux_amd64/flakybot
diff --git a/.kokoro/test-samples-impl.sh b/.kokoro/test-samples-impl.sh
index 311a8d54..8a324c9c 100755
--- a/.kokoro/test-samples-impl.sh
+++ b/.kokoro/test-samples-impl.sh
@@ -80,7 +80,7 @@ for file in samples/**/requirements.txt; do
     EXIT=$?
 
     # If this is a periodic build, send the test log to the FlakyBot.
-    # See https://github.com/googleapis/repo-automation-bots/tree/master/packages/flakybot.
+    # See https://github.com/googleapis/repo-automation-bots/tree/main/packages/flakybot.
     if [[ $KOKORO_BUILD_ARTIFACTS_SUBDIR = *"periodic"* ]]; then
       chmod +x $KOKORO_GFILE_DIR/linux_amd64/flakybot
       $KOKORO_GFILE_DIR/linux_amd64/flakybot
diff --git a/CONTRIBUTING.rst b/CONTRIBUTING.rst
index b6278e10..2083c729 100644
--- a/CONTRIBUTING.rst
+++ b/CONTRIBUTING.rst
@@ -50,9 +50,9 @@ You'll have to create a development environment using a Git checkout:
    # Configure remotes such that you can pull changes from the googleapis/python-bigquery-sqlalchemy
    # repository into your local repository.
    $ git remote add upstream git@github.com:googleapis/python-bigquery-sqlalchemy.git
-   # fetch and merge changes from upstream into master
+   # fetch and merge changes from upstream into main
    $ git fetch upstream
-   $ git merge upstream/master
+   $ git merge upstream/main
 
 Now your local repo is set up such that you will push changes to your GitHub
 repo, from which you can submit a pull request.
@@ -110,12 +110,12 @@ Coding Style
   variables::
 
    export GOOGLE_CLOUD_TESTING_REMOTE="upstream"
-   export GOOGLE_CLOUD_TESTING_BRANCH="master"
+   export GOOGLE_CLOUD_TESTING_BRANCH="main"
 
   By doing this, you are specifying the location of the most up-to-date
   version of ``python-bigquery-sqlalchemy``. The the suggested remote name ``upstream``
   should point to the official ``googleapis`` checkout and the
-  the branch should be the main branch on that remote (``master``).
+  the branch should be the main branch on that remote (``main``).
 
 - This repository contains configuration for the
   `pre-commit <https://pre-commit.com/>`__ tool, which automates checking
@@ -209,7 +209,7 @@ The `description on PyPI`_ for the project comes directly from the
 ``README``. Due to the reStructuredText (``rst``) parser used by
 PyPI, relative links which will work on GitHub (e.g. ``CONTRIBUTING.rst``
 instead of
-``https://github.com/googleapis/python-bigquery-sqlalchemy/blob/master/CONTRIBUTING.rst``)
+``https://github.com/googleapis/python-bigquery-sqlalchemy/blob/main/CONTRIBUTING.rst``)
 may cause problems creating links or rendering the description.
 
 .. _description on PyPI: https://pypi.org/project/sqlalchemy-bigquery
@@ -234,7 +234,7 @@ We support:
 
 Supported versions can be found in our ``noxfile.py`` `config`_.
 
-.. _config: https://github.com/googleapis/python-bigquery-sqlalchemy/blob/master/noxfile.py
+.. _config: https://github.com/googleapis/python-bigquery-sqlalchemy/blob/main/noxfile.py
 
 
 We also explicitly decided to support Python 3 beginning with version 3.6.
diff --git a/docs/conf.py b/docs/conf.py
index 6e45e97c..620d2a06 100644
--- a/docs/conf.py
+++ b/docs/conf.py
@@ -76,8 +76,8 @@
 # The encoding of source files.
 # source_encoding = 'utf-8-sig'
 
-# The master toctree document.
-master_doc = "index"
+# The root toctree document.
+root_doc = "index"
 
 # General information about the project.
 project = "sqlalchemy-bigquery"
@@ -280,7 +280,7 @@
 #  author, documentclass [howto, manual, or own class]).
 latex_documents = [
     (
-        master_doc,
+        root_doc,
         "sqlalchemy-bigquery.tex",
         "sqlalchemy-bigquery Documentation",
         author,
@@ -314,13 +314,7 @@
 # One entry per manual page. List of tuples
 # (source start file, name, description, authors, manual section).
 man_pages = [
-    (
-        master_doc,
-        "sqlalchemy-bigquery",
-        "sqlalchemy-bigquery Documentation",
-        [author],
-        1,
-    )
+    (root_doc, "sqlalchemy-bigquery", "sqlalchemy-bigquery Documentation", [author], 1,)
 ]
 
 # If true, show URL addresses after external links.
@@ -334,7 +328,7 @@
 #  dir menu entry, description, category)
 texinfo_documents = [
     (
-        master_doc,
+        root_doc,
         "sqlalchemy-bigquery",
         "sqlalchemy-bigquery Documentation",
         author,
diff --git a/owlbot.py b/owlbot.py
index b6cfe7ff..f8633351 100644
--- a/owlbot.py
+++ b/owlbot.py
@@ -172,7 +172,6 @@ def compliance(session):
 
 
 # Add DB config for SQLAlchemy dialect test suite.
-# https://github.com/sqlalchemy/sqlalchemy/blob/master/README.dialects.rst
 # https://github.com/googleapis/python-bigquery-sqlalchemy/issues/89
 s.replace(
     ["setup.cfg"],
@@ -195,6 +194,51 @@ def compliance(session):
 
 python.py_samples(skip_readmes=True)
 
+# ----------------------------------------------------------------------------
+# Remove the replacements below once https://github.com/googleapis/synthtool/pull/1188 is merged
+
+# Update googleapis/repo-automation-bots repo to main in .kokoro/*.sh files
+s.replace(".kokoro/*.sh", "repo-automation-bots/tree/master", "repo-automation-bots/tree/main")
+
+# Customize CONTRIBUTING.rst to replace master with main
+s.replace(
+    "CONTRIBUTING.rst",
+    "fetch and merge changes from upstream into master",
+    "fetch and merge changes from upstream into main",
+)
+
+s.replace(
+    "CONTRIBUTING.rst",
+    "git merge upstream/master",
+    "git merge upstream/main",
+)
+
+s.replace(
+    "CONTRIBUTING.rst",
+    """export GOOGLE_CLOUD_TESTING_BRANCH=\"master\"""",
+    """export GOOGLE_CLOUD_TESTING_BRANCH=\"main\"""",
+)
+
+s.replace(
+    "CONTRIBUTING.rst",
+    "remote \(``master``\)",
+    "remote (``main``)",
+)
+
+s.replace(
+    "CONTRIBUTING.rst",
+    "blob/master/CONTRIBUTING.rst",
+    "blob/main/CONTRIBUTING.rst",
+)
+
+s.replace(
+    "CONTRIBUTING.rst",
+    "blob/master/noxfile.py",
+    "blob/main/noxfile.py",
+)
+
+s.replace("docs/conf.py", "master", "root")
+
 # ----------------------------------------------------------------------------
 # Final cleanup
 # ----------------------------------------------------------------------------
diff --git a/release-procedure.md b/release-procedure.md
index ba5291dd..c3d68f31 100644
--- a/release-procedure.md
+++ b/release-procedure.md
@@ -1,10 +1,10 @@
 # sqlalchemy-bigquery release procedure
 
-*   Checkout master branch
+*   Checkout main branch
 
-        git fetch upstream master
-        git checkout master
-        git rebase -i upstream/master
+        git fetch upstream main
+        git checkout main
+        git rebase -i upstream/main
 
 *   Update version number in `setup.py`
 
@@ -13,7 +13,7 @@
 *   Commit and push
 
         git commit -m "Release x.x.x"
-        git push upstream master
+        git push upstream main
 
 *   Build the package