diff --git a/.github/workflows/auto-release.yml b/.github/workflows/auto-release.yml
index 9526e93d55c6..eeb04e11f066 100644
--- a/.github/workflows/auto-release.yml
+++ b/.github/workflows/auto-release.yml
@@ -9,7 +9,7 @@ on:
 # This workflow tirggers a release when merging a branch with the pattern `prepare-release/VERSION` into master.
 jobs:
   release:
-    runs-on: ubuntu-20.04
+    runs-on: ubuntu-24.04
     name: 'Prepare a new version'
 
     steps:
diff --git a/.github/workflows/build.yml b/.github/workflows/build.yml
index c931460b4489..69036ea7a261 100644
--- a/.github/workflows/build.yml
+++ b/.github/workflows/build.yml
@@ -31,7 +31,6 @@ env:
     ${{ github.workspace }}/node_modules
     ${{ github.workspace }}/packages/*/node_modules
     ${{ github.workspace }}/dev-packages/*/node_modules
-    ~/.cache/ms-playwright/
     ~/.cache/mongodb-binaries/
 
   # DEPENDENCY_CACHE_KEY: can't be set here because we don't have access to yarn.lock
@@ -50,7 +49,7 @@ env:
     ${{ github.workspace }}/packages/utils/esm
 
   BUILD_CACHE_KEY: ${{ github.event.inputs.commit || github.sha }}
-  BUILD_PROFILING_NODE_CACHE_TARBALL_KEY: profiling-node-tarball-${{ github.event.inputs.commit || github.sha }}
+  BUILD_CACHE_TARBALL_KEY: tarballs-${{ github.event.inputs.commit || github.sha }}
 
   # GH will use the first restore-key it finds that matches
   # So it will start by looking for one from the same branch, else take the newest one it can find elsewhere
@@ -63,7 +62,7 @@ env:
 jobs:
   job_get_metadata:
     name: Get Metadata
-    runs-on: ubuntu-20.04
+    runs-on: ubuntu-24.04
     permissions:
       pull-requests: read
     steps:
@@ -135,16 +134,6 @@ jobs:
               - 'packages/remix/**'
               - 'packages/node/**'
               - 'packages/react/**'
-            profiling_node:
-              - *shared
-              - 'packages/node/**'
-              - 'packages/node-experimental/**'
-              - 'packages/profiling-node/**'
-              - 'dev-packages/e2e-tests/test-applications/node-profiling/**'
-            profiling_node_bindings:
-              - *workflow
-              - 'packages/profiling-node/**'
-              - 'dev-packages/e2e-tests/test-applications/node-profiling/**'
             deno:
               - *shared
               - *browser
@@ -162,8 +151,6 @@ jobs:
       changed_ember: ${{ steps.changed.outputs.ember }}
       changed_remix: ${{ steps.changed.outputs.remix }}
       changed_node: ${{ steps.changed.outputs.node }}
-      changed_profiling_node: ${{ steps.changed.outputs.profiling_node }}
-      changed_profiling_node_bindings: ${{ steps.changed.outputs.profiling_node_bindings }}
       changed_deno: ${{ steps.changed.outputs.deno }}
       changed_browser: ${{ steps.changed.outputs.browser }}
       changed_browser_integration: ${{ steps.changed.outputs.browser_integration }}
@@ -183,7 +170,7 @@ jobs:
   job_install_deps:
     name: Install Dependencies
     needs: job_get_metadata
-    runs-on: ubuntu-20.04
+    runs-on: ubuntu-24.04
     timeout-minutes: 15
     if: |
       (needs.job_get_metadata.outputs.is_gitflow_sync == 'false' && needs.job_get_metadata.outputs.has_gitflow_label == 'false')
@@ -218,7 +205,7 @@ jobs:
   job_check_branches:
     name: Check PR branches
     needs: job_get_metadata
-    runs-on: ubuntu-20.04
+    runs-on: ubuntu-24.04
     if: github.event_name == 'pull_request'
     permissions:
       pull-requests: write
@@ -233,7 +220,7 @@ jobs:
   job_build:
     name: Build
     needs: [job_get_metadata, job_install_deps]
-    runs-on: ubuntu-20.04-large-js
+    runs-on: ubuntu-24.04-large-js
     timeout-minutes: 30
     if: |
       (needs.job_get_metadata.outputs.changed_any_code == 'true' || github.event_name != 'pull_request')
@@ -291,10 +278,8 @@ jobs:
     name: Size Check
     needs: [job_get_metadata, job_build]
     timeout-minutes: 15
-    runs-on: ubuntu-20.04
-    if:
-      github.event_name == 'pull_request' || needs.job_get_metadata.outputs.is_develop == 'true' ||
-      needs.job_get_metadata.outputs.is_release == 'true'
+    runs-on: ubuntu-24.04
+    if: false
     steps:
       - name: Check out current commit (${{ needs.job_get_metadata.outputs.commit_label }})
         uses: actions/checkout@v4
@@ -326,7 +311,7 @@ jobs:
     # inter-package dependencies resolve cleanly.
     needs: [job_get_metadata, job_build]
     timeout-minutes: 10
-    runs-on: ubuntu-20.04
+    runs-on: ubuntu-24.04
     steps:
       - name: Check out current commit (${{ needs.job_get_metadata.outputs.commit_label }})
         uses: actions/checkout@v4
@@ -351,7 +336,7 @@ jobs:
     name: Check file formatting
     needs: [job_get_metadata, job_install_deps]
     timeout-minutes: 10
-    runs-on: ubuntu-20.04
+    runs-on: ubuntu-24.04
     steps:
       - name: Check out current commit (${{ needs.job_get_metadata.outputs.commit_label }})
         uses: actions/checkout@v4
@@ -374,7 +359,7 @@ jobs:
     name: Circular Dependency Check
     needs: [job_get_metadata, job_build]
     timeout-minutes: 10
-    runs-on: ubuntu-20.04
+    runs-on: ubuntu-24.04
     steps:
       - name: Check out current commit (${{ needs.job_get_metadata.outputs.commit_label }})
         uses: actions/checkout@v4
@@ -393,8 +378,8 @@ jobs:
 
   job_artifacts:
     name: Upload Artifacts
-    needs: [job_get_metadata, job_build, job_compile_bindings_profiling_node]
-    runs-on: ubuntu-20.04
+    needs: [job_get_metadata, job_build]
+    runs-on: ubuntu-24.04
     # Build artifacts are only needed for releasing workflow.
     if: needs.job_get_metadata.outputs.is_release == 'true'
     steps:
@@ -411,15 +396,7 @@ jobs:
         env:
           DEPENDENCY_CACHE_KEY: ${{ needs.job_build.outputs.dependency_cache_key }}
       - name: Pack tarballs
-        # Profiling tarball is built separately as we assemble the precompiled binaries
-        run: yarn build:tarball --ignore @sentry/profiling-node
-
-      - name: Restore profiling tarball
-        uses: actions/cache/restore@v4
-        with:
-          key: ${{ env.BUILD_PROFILING_NODE_CACHE_TARBALL_KEY }}
-          path: ${{ github.workspace }}/packages/*/*.tgz
-
+        run: yarn build:tarball
       - name: Archive artifacts
         uses: actions/upload-artifact@v4
         with:
@@ -436,7 +413,7 @@ jobs:
     name: Browser Unit Tests
     needs: [job_get_metadata, job_build]
     timeout-minutes: 10
-    runs-on: ubuntu-20.04
+    runs-on: ubuntu-24.04
     steps:
       - name: Check out current commit (${{ needs.job_get_metadata.outputs.commit_label }})
         uses: actions/checkout@v4
@@ -463,9 +440,7 @@ jobs:
     name: Bun Unit Tests
     needs: [job_get_metadata, job_build]
     timeout-minutes: 10
-    runs-on: ubuntu-20.04
-    strategy:
-      fail-fast: false
+    runs-on: ubuntu-24.04
     steps:
       - name: Check out current commit (${{ needs.job_get_metadata.outputs.commit_label }})
         uses: actions/checkout@v4
@@ -494,7 +469,7 @@ jobs:
     needs: [job_get_metadata, job_build]
     if: needs.job_get_metadata.outputs.changed_deno == 'true' || github.event_name != 'pull_request'
     timeout-minutes: 10
-    runs-on: ubuntu-20.04
+    runs-on: ubuntu-24.04
     strategy:
       fail-fast: false
     steps:
@@ -529,7 +504,7 @@ jobs:
     if: needs.job_get_metadata.outputs.changed_node == 'true' || github.event_name != 'pull_request'
     needs: [job_get_metadata, job_build]
     timeout-minutes: 10
-    runs-on: ubuntu-20.04
+    runs-on: ubuntu-24.04
     strategy:
       fail-fast: false
       matrix:
@@ -558,40 +533,12 @@ jobs:
         with:
           token: ${{ secrets.CODECOV_TOKEN }}
 
-  job_profiling_node_unit_tests:
-    name: Node Profiling Unit Tests
-    needs: [job_get_metadata, job_build]
-    if: needs.job_get_metadata.outputs.changed_node == 'true' || needs.job_get_metadata.outputs.changed_profiling_node == 'true' || github.event_name != 'pull_request'
-    runs-on: ubuntu-latest
-    timeout-minutes: 10
-    steps:
-      - name: Check out current commit
-        uses: actions/checkout@v4
-        with:
-          ref: ${{ env.HEAD_COMMIT }}
-      - uses: actions/setup-node@v4
-        with:
-          node-version: 20
-      - uses: actions/setup-python@v5
-        with:
-          python-version: '3.11.7'
-      - name: Restore caches
-        uses: ./.github/actions/restore-cache
-        env:
-          DEPENDENCY_CACHE_KEY: ${{ needs.job_build.outputs.dependency_cache_key }}
-      - name: Build Configure node-gyp
-        run: yarn lerna run build:bindings:configure --scope @sentry/profiling-node
-      - name: Build Bindings for Current Environment
-        run: yarn build --scope @sentry/profiling-node
-      - name: Unit Test
-        run: yarn lerna run test --scope @sentry/profiling-node
-
   job_nextjs_integration_test:
     name: Nextjs (Node ${{ matrix.node }}) Tests
     needs: [job_get_metadata, job_build]
-    if: needs.job_get_metadata.outputs.changed_nextjs == 'true' || github.event_name != 'pull_request'
+    if: false
     timeout-minutes: 25
-    runs-on: ubuntu-20.04
+    runs-on: ubuntu-24.04
     strategy:
       fail-fast: false
       matrix:
@@ -623,12 +570,9 @@ jobs:
           key: ${{ runner.os }}-Playwright-${{steps.playwright-version.outputs.version}}
       - name: Install Playwright browser if not cached
         if: steps.playwright-cache.outputs.cache-hit != 'true' && matrix.node >= 14
-        run: npx playwright install --with-deps
+        run: npx playwright install
         env:
           PLAYWRIGHT_BROWSERS_PATH: ${{steps.npm-cache-dir.outputs.dir}}
-      - name: Install OS dependencies of Playwright if cache hit
-        if: steps.playwright-cache.outputs.cache-hit == 'true' && matrix.node >= 14
-        run: npx playwright install-deps
       - name: Run tests
         env:
           NODE_VERSION: ${{ matrix.node }}
@@ -639,8 +583,8 @@ jobs:
   job_browser_playwright_tests:
     name: Playwright (${{ matrix.bundle }}${{ matrix.shard && format(' {0}/{1}', matrix.shard, matrix.shards) || ''}}) Tests
     needs: [job_get_metadata, job_build]
-    if: needs.job_get_metadata.outputs.changed_browser_integration == 'true' || github.event_name != 'pull_request'
-    runs-on: ubuntu-20.04-large-js
+    if: false
+    runs-on: ubuntu-24.04-large-js
     timeout-minutes: 25
     strategy:
       fail-fast: false
@@ -717,12 +661,9 @@ jobs:
           key: ${{ runner.os }}-Playwright-${{steps.playwright-version.outputs.version}}
       - name: Install Playwright browser if not cached
         if: steps.playwright-cache.outputs.cache-hit != 'true'
-        run: npx playwright install --with-deps
+        run: npx playwright install
         env:
           PLAYWRIGHT_BROWSERS_PATH: ${{steps.npm-cache-dir.outputs.dir}}
-      - name: Install OS dependencies of Playwright if cache hit
-        if: steps.playwright-cache.outputs.cache-hit == 'true'
-        run: npx playwright install-deps
       - name: Run Playwright tests
         env:
           PW_BUNDLE: ${{ matrix.bundle }}
@@ -732,8 +673,8 @@ jobs:
   job_browser_loader_tests:
     name: Playwright Loader (${{ matrix.bundle }}) Tests
     needs: [job_get_metadata, job_build]
-    if: needs.job_get_metadata.outputs.changed_browser_integration == 'true' || github.event_name != 'pull_request'
-    runs-on: ubuntu-20.04
+    if: false
+    runs-on: ubuntu-24.04
     timeout-minutes: 15
     strategy:
       fail-fast: false
@@ -773,12 +714,9 @@ jobs:
           key: ${{ runner.os }}-Playwright-${{steps.playwright-version.outputs.version}}
       - name: Install Playwright browser if not cached
         if: steps.playwright-cache.outputs.cache-hit != 'true'
-        run: npx playwright install --with-deps
+        run: npx playwright install
         env:
           PLAYWRIGHT_BROWSERS_PATH: ${{steps.npm-cache-dir.outputs.dir}}
-      - name: Install OS dependencies of Playwright if cache hit
-        if: steps.playwright-cache.outputs.cache-hit == 'true'
-        run: npx playwright install-deps
       - name: Run Playwright Loader tests
         env:
           PW_BUNDLE: ${{ matrix.bundle }}
@@ -789,8 +727,8 @@ jobs:
   job_browser_integration_tests:
     name: Browser (${{ matrix.browser }}) Tests
     needs: [job_get_metadata, job_build]
-    if: needs.job_get_metadata.outputs.changed_browser == 'true' || github.event_name != 'pull_request'
-    runs-on: ubuntu-20.04-large-js
+    if: false
+    runs-on: ubuntu-24.04-large-js
     timeout-minutes: 20
     strategy:
       fail-fast: false
@@ -817,13 +755,12 @@ jobs:
           KARMA_BROWSER: ${{ matrix.browser }}
         run: |
           cd packages/browser
-          [[ $KARMA_BROWSER == WebkitHeadless ]] && yarn run playwright install-deps webkit
           yarn test:integration
 
   job_browser_build_tests:
     name: Browser Build Tests
     needs: [job_get_metadata, job_build]
-    runs-on: ubuntu-20.04
+    runs-on: ubuntu-24.04
     timeout-minutes: 5
     steps:
       - name: Check out current commit (${{ needs.job_get_metadata.outputs.commit_label }})
@@ -850,7 +787,7 @@ jobs:
   job_check_for_faulty_dts:
     name: Check for faulty .d.ts files
     needs: [job_get_metadata, job_build]
-    runs-on: ubuntu-20.04
+    runs-on: ubuntu-24.04
     timeout-minutes: 5
     steps:
       - name: Check out current commit (${{ needs.job_get_metadata.outputs.commit_label }})
@@ -879,7 +816,7 @@ jobs:
       Tests
     needs: [job_get_metadata, job_build]
     if: needs.job_get_metadata.outputs.changed_node == 'true' || github.event_name != 'pull_request'
-    runs-on: ubuntu-20.04
+    runs-on: ubuntu-24.04
     timeout-minutes: 15
     strategy:
       fail-fast: false
@@ -919,8 +856,8 @@ jobs:
   job_remix_integration_tests:
     name: Remix v${{ matrix.remix }} (Node ${{ matrix.node }}) ${{ matrix.tracingIntegration && 'TracingIntegration'}} Tests
     needs: [job_get_metadata, job_build]
-    if: needs.job_get_metadata.outputs.changed_remix == 'true' || github.event_name != 'pull_request'
-    runs-on: ubuntu-20.04
+    if: false
+    runs-on: ubuntu-24.04
     timeout-minutes: 10
     strategy:
       fail-fast: false
@@ -963,13 +900,9 @@ jobs:
     # - The build job was successful, not skipped
     # - AND if the profiling node bindings were either successful or skipped
     # AND if this is not a PR from a fork or dependabot
-    if: |
-      always() && needs.job_build.result == 'success' &&
-      (needs.job_compile_bindings_profiling_node.result == 'success' || needs.job_compile_bindings_profiling_node.result == 'skipped') &&
-      (github.event_name != 'pull_request' || github.event.pull_request.head.repo.full_name == github.repository) &&
-      github.actor != 'dependabot[bot]'
-    needs: [job_get_metadata, job_build, job_compile_bindings_profiling_node]
-    runs-on: ubuntu-20.04-large-js
+    if: false
+    needs: [job_get_metadata, job_build]
+    runs-on: ubuntu-24.04-large-js
     timeout-minutes: 15
     steps:
       - name: Check out current commit (${{ needs.job_get_metadata.outputs.commit_label }})
@@ -992,36 +925,12 @@ jobs:
           # On develop branch, we want to _store_ the cache (so it can be used by other branches), but never _restore_ from it
           restore-keys: ${{ env.NX_CACHE_RESTORE_KEYS }}
       - name: Build tarballs
-        run: yarn build:tarball --ignore @sentry/profiling-node
-
-      # Rebuild profiling by compiling TS and pull the precompiled binary artifacts
-      - name: Build Profiling Node
-        if: |
-          (needs.job_get_metadata.outputs.changed_profiling_node_bindings == 'true') ||
-          (needs.job_get_metadata.outputs.is_release == 'true') ||
-          (github.event_name != 'pull_request')
-        run: yarn lerna run build:lib --scope @sentry/profiling-node
-
-      - name: Extract Profiling Node Prebuilt Binaries
-        # @TODO: v4 breaks convenient merging of same name artifacts
-        # https://github.com/actions/upload-artifact/issues/478
-        if: |
-          (needs.job_get_metadata.outputs.changed_profiling_node_bindings == 'true') ||
-          (github.event_name != 'pull_request')
-        uses: actions/download-artifact@v3
-        with:
-          name: profiling-node-binaries-${{ github.sha }}
-          path: ${{ github.workspace }}/packages/profiling-node/lib/
-
-      - name: Build Profiling tarball
-        run: yarn build:tarball --scope @sentry/profiling-node
-      # End rebuild profiling
-
+        run: yarn build:tarball
       - name: Stores tarballs in cache
         uses: actions/cache/save@v4
         with:
           path: ${{ github.workspace }}/packages/*/*.tgz
-          key: ${{ env.BUILD_PROFILING_NODE_CACHE_TARBALL_KEY }}
+          key: ${{ env.BUILD_CACHE_TARBALL_KEY }}
 
   job_e2e_tests:
     name: E2E ${{ matrix.label || matrix.test-application }} Test
@@ -1029,12 +938,9 @@ jobs:
     # Dependabot PRs sadly also don't have access to secrets, so we skip them as well
     # We need to add the `always()` check here because the previous step has this as well :(
     # See: https://github.com/actions/runner/issues/2205
-    if:
-      always() && needs.job_e2e_prepare.result == 'success' &&
-      (github.event_name != 'pull_request' || github.event.pull_request.head.repo.full_name == github.repository) &&
-      github.actor != 'dependabot[bot]'
+    if: false
     needs: [job_get_metadata, job_build, job_e2e_prepare]
-    runs-on: ubuntu-20.04
+    runs-on: ubuntu-24.04
     timeout-minutes: 10
     env:
       E2E_TEST_AUTH_TOKEN: ${{ secrets.E2E_TEST_AUTH_TOKEN }}
@@ -1071,7 +977,8 @@ jobs:
             'node-experimental-fastify-app',
             'node-hapi-app',
             'node-exports-test-app',
-            'vue-3'
+            'vue-3',
+            'node-profiling'
           ]
         build-command:
           - false
@@ -1116,7 +1023,7 @@ jobs:
         uses: actions/cache/restore@v4
         with:
           path: ${{ github.workspace }}/packages/*/*.tgz
-          key: ${{ env.BUILD_PROFILING_NODE_CACHE_TARBALL_KEY }}
+          key: ${{ env.BUILD_CACHE_TARBALL_KEY }}
 
       - name: Get node version
         id: versions
@@ -1152,106 +1059,16 @@ jobs:
           projectName: ${{ secrets.CLOUDFLARE_PROJECT_NAME }}
           directory: dist
           workingDirectory: dev-packages/e2e-tests/test-applications/${{ matrix.test-application }}
-
-  job_profiling_e2e_tests:
-    name: E2E ${{ matrix.label || matrix.test-application }} Test
-    # We only run E2E tests for non-fork PRs because the E2E tests require secrets to work and they can't be accessed from forks
-    # Dependabot PRs sadly also don't have access to secrets, so we skip them as well
-    # We need to add the `always()` check here because the previous step has this as well :(
-    # See: https://github.com/actions/runner/issues/2205
-    if:
-      # Only run profiling e2e tests if profiling node bindings have changed
-      always() && needs.job_e2e_prepare.result == 'success' &&
-      (github.event_name != 'pull_request' || github.event.pull_request.head.repo.full_name == github.repository) &&
-      github.actor != 'dependabot[bot]' && (
-        (needs.job_get_metadata.outputs.changed_profiling_node_bindings == 'true') ||
-        (needs.job_get_metadata.outputs.is_release == 'true') ||
-        (github.event_name != 'pull_request')
-      )
-    needs: [job_get_metadata, job_build, job_e2e_prepare]
-    runs-on: ubuntu-20.04
-    timeout-minutes: 10
-    env:
-      E2E_TEST_AUTH_TOKEN: ${{ secrets.E2E_TEST_AUTH_TOKEN }}
-      E2E_TEST_DSN: ${{ secrets.E2E_TEST_DSN }}
-      E2E_TEST_SENTRY_ORG_SLUG: 'sentry-javascript-sdks'
-      E2E_TEST_SENTRY_TEST_PROJECT: 'sentry-javascript-e2e-tests'
-    strategy:
-      fail-fast: false
-      matrix:
-        test-application: ['node-profiling']
-        build-command:
-          - false
-        label:
-          - false
-    steps:
-      - name: Check out current commit (${{ needs.job_get_metadata.outputs.commit_label }})
-        uses: actions/checkout@v4
-        with:
-          ref: ${{ env.HEAD_COMMIT }}
-      - uses: pnpm/action-setup@v2
-        with:
-          version: 8.3.1
-      - name: Set up Node
-        uses: actions/setup-node@v4
-        with:
-          node-version-file: 'dev-packages/e2e-tests/package.json'
-      - name: Restore caches
-        uses: ./.github/actions/restore-cache
-        env:
-          DEPENDENCY_CACHE_KEY: ${{ needs.job_build.outputs.dependency_cache_key }}
-      - name: Build Profiling Node
-        run: yarn lerna run build:lib --scope @sentry/profiling-node
-      - name: Extract Profiling Node Prebuilt Binaries
-        uses: actions/download-artifact@v3
-        with:
-          name: profiling-node-binaries-${{ github.sha }}
-          path: ${{ github.workspace }}/packages/profiling-node/lib/
-      - name: Build Profiling tarball
-        run: yarn build:tarball --scope @sentry/profiling-node
-      - name: Restore tarball cache
-        uses: actions/cache/restore@v4
-        with:
-          path: ${{ github.workspace }}/packages/*/*.tgz
-          key: ${{ env.BUILD_PROFILING_NODE_CACHE_TARBALL_KEY }}
-
-      - name: Get node version
-        id: versions
-        run: |
-          echo "echo node=$(jq -r '.volta.node' dev-packages/e2e-tests/package.json)" >> $GITHUB_OUTPUT
-
-      - name: Validate Verdaccio
-        run: yarn test:validate
-        working-directory: dev-packages/e2e-tests
-
-      - name: Prepare Verdaccio
-        run: yarn test:prepare
-        working-directory: dev-packages/e2e-tests
-        env:
-          E2E_TEST_PUBLISH_SCRIPT_NODE_VERSION: ${{ steps.versions.outputs.node }}
-
-      - name: Build E2E app
-        working-directory: dev-packages/e2e-tests/test-applications/${{ matrix.test-application }}
-        timeout-minutes: 5
-        run: yarn ${{ matrix.build-command || 'test:build' }}
-
-      - name: Run E2E test
-        working-directory: dev-packages/e2e-tests/test-applications/${{ matrix.test-application }}
-        timeout-minutes: 5
-        run: yarn test:assert
-
   job_required_jobs_passed:
     name: All required jobs passed or were skipped
     needs:
       [
         job_build,
-        job_compile_bindings_profiling_node,
         job_browser_build_tests,
         job_browser_unit_tests,
         job_bun_unit_tests,
         job_deno_unit_tests,
         job_node_unit_tests,
-        job_profiling_node_unit_tests,
         job_nextjs_integration_test,
         job_node_integration_tests,
         job_browser_playwright_tests,
@@ -1259,7 +1076,6 @@ jobs:
         job_browser_loader_tests,
         job_remix_integration_tests,
         job_e2e_tests,
-        job_profiling_e2e_tests,
         job_artifacts,
         job_lint,
         job_check_format,
@@ -1267,7 +1083,7 @@ jobs:
       ]
     # Always run this, even if a dependent job failed
     if: always()
-    runs-on: ubuntu-20.04
+    runs-on: ubuntu-24.04
     steps:
       - name: Check for failures
         if: contains(needs.*.result, 'failure')
@@ -1277,7 +1093,7 @@ jobs:
   overhead_metrics:
     name: Overhead metrics
     needs: [job_get_metadata, job_build]
-    runs-on: ubuntu-20.04
+    runs-on: ubuntu-24.04
     timeout-minutes: 30
     if: |
       contains(github.event.pull_request.labels.*.name, 'ci-overhead-measurements')
@@ -1314,259 +1130,3 @@ jobs:
         with:
           name: ${{ steps.process.outputs.artifactName }}
           path: ${{ steps.process.outputs.artifactPath }}
-
-  job_compile_bindings_profiling_node:
-    name: Compile & Test Profiling Bindings (v${{ matrix.node }}) ${{ matrix.target_platform || matrix.os }}, ${{ matrix.node || matrix.container }}, ${{ matrix.arch || matrix.container }}, ${{ contains(matrix.container, 'alpine') && 'musl' || 'glibc'  }}
-    needs: [job_get_metadata, job_install_deps, job_build]
-    # Compiling bindings can be very slow (especially on windows), so only run precompile
-    # Skip precompile unless we are on a release branch as precompile slows down CI times.
-    if: |
-      (needs.job_get_metadata.outputs.changed_profiling_node_bindings == 'true') ||
-      (needs.job_get_metadata.outputs.is_release == 'true') ||
-      (github.event_name != 'pull_request')
-    runs-on: ${{ matrix.os }}
-    container: ${{ matrix.container }}
-    timeout-minutes: 30
-    strategy:
-      fail-fast: false
-      matrix:
-        include:
-            # x64 glibc
-          - os: ubuntu-20.04
-            node: 16
-          - os: ubuntu-20.04
-            node: 18
-          - os: ubuntu-20.04
-            node: 20
-          - os: ubuntu-20.04
-            node: 22
-
-            # x64 musl
-          - os: ubuntu-20.04
-            container: node:16-alpine3.16
-            node: 16
-          - os: ubuntu-20.04
-            container: node:18-alpine3.17
-            node: 18
-          - os: ubuntu-20.04
-            container: node:20-alpine3.17
-            node: 20
-          - os: ubuntu-20.04
-            container: node:22-alpine3.18
-            node: 22
-
-            # arm64 glibc
-          - os: ubuntu-20.04
-            arch: arm64
-            node: 16
-          - os: ubuntu-20.04
-            arch: arm64
-            node: 18
-          - os: ubuntu-20.04
-            arch: arm64
-            node: 20
-          - os: ubuntu-20.04
-            arch: arm64
-            node: 22
-
-            # arm64 musl
-          - os: ubuntu-20.04
-            container: node:16-alpine3.16
-            arch: arm64
-            node: 16
-          - os: ubuntu-20.04
-            arch: arm64
-            container: node:18-alpine3.17
-            node: 18
-          - os: ubuntu-20.04
-            arch: arm64
-            container: node:20-alpine3.17
-            node: 20
-          - os: ubuntu-20.04
-            arch: arm64
-            container: node:22-alpine3.18
-            node: 22
-
-            # macos x64
-          - os: macos-13
-            node: 16
-            arch: x64
-          - os: macos-13
-            node: 18
-            arch: x64
-          - os: macos-13
-            node: 20
-            arch: x64
-          - os: macos-13
-            node: 22
-            arch: x64
-
-            # macos arm64
-          - os: macos-13
-            arch: arm64
-            node: 16
-            target_platform: darwin
-          - os: macos-13
-            arch: arm64
-            node: 18
-            target_platform: darwin
-          - os: macos-13
-            arch: arm64
-            node: 20
-            target_platform: darwin
-          - os: macos-13
-            arch: arm64
-            node: 22
-            target_platform: darwin
-
-            # windows x64
-          - os: windows-2022
-            node: 16
-            arch: x64
-          - os: windows-2022
-            node: 18
-            arch: x64
-          - os: windows-2022
-            node: 20
-            arch: x64
-          - os: windows-2022
-            node: 22
-            arch: x64
-
-    steps:
-      - name: Setup (alpine)
-        if: contains(matrix.container, 'alpine')
-        run: |
-          apk add --no-cache build-base git g++ make curl python3
-          ln -sf python3 /usr/bin/python
-
-      - name: Check out current commit (${{ needs.job_get_metadata.outputs.commit_label }})
-        uses: actions/checkout@v4
-        with:
-          ref: ${{ env.HEAD_COMMIT }}
-
-      - name: Restore dependency cache
-        uses: actions/cache/restore@v4
-        id: restore-dependencies
-        with:
-          path: ${{ env.CACHED_DEPENDENCY_PATHS }}
-          key: ${{ needs.job_install_deps.outputs.dependency_cache_key }}
-          enableCrossOsArchive: true
-
-      - name: Restore build cache
-        uses: actions/cache/restore@v4
-        id: restore-build
-        with:
-          path: ${{ env.CACHED_BUILD_PATHS }}
-          key: ${{ needs.job_build.outputs.dependency_cache_key }}
-          enableCrossOsArchive: true
-
-      - name: Configure safe directory
-        run: |
-          git config --global --add safe.directory "*"
-
-      - name: Install yarn
-        run: npm i -g yarn@1.22.19 --force
-
-      - name: Increase yarn network timeout on Windows
-        if: contains(matrix.os, 'windows')
-        run: yarn config set network-timeout 600000 -g
-
-      - name: Setup python
-        uses: actions/setup-python@v5
-        if: ${{ !contains(matrix.container, 'alpine') }}
-        id: python-setup
-        with:
-          python-version: '3.8.10'
-
-      - name: Setup Node
-        uses: actions/setup-node@v4
-        with:
-          node-version: ${{ matrix.node }}
-
-      - name: Install Dependencies
-        if: steps.restore-dependencies.outputs.cache-hit != 'true'
-        run: yarn install --frozen-lockfile --ignore-engines --ignore-scripts
-
-      - name: Setup (arm64| ${{ contains(matrix.container, 'alpine') && 'musl' || 'glibc'  }})
-        if: matrix.arch == 'arm64' && !contains(matrix.container, 'alpine') && matrix.target_platform != 'darwin'
-        run: |
-          sudo apt-get update
-          sudo apt install -y gcc-aarch64-linux-gnu g++-aarch64-linux-gnu
-
-      - name: Setup Musl
-        if: contains(matrix.container, 'alpine')
-        run: |
-          cd packages/profiling-node
-          curl -OL https://musl.cc/aarch64-linux-musl-cross.tgz
-          tar -xzvf aarch64-linux-musl-cross.tgz
-          $(pwd)/aarch64-linux-musl-cross/bin/aarch64-linux-musl-gcc --version
-
-      # configure node-gyp
-      - name: Configure node-gyp
-        if: matrix.arch != 'arm64'
-        run: |
-          cd packages/profiling-node
-          yarn build:bindings:configure
-
-      - name: Configure node-gyp (arm64, ${{ contains(matrix.container, 'alpine') && 'musl' || 'glibc'  }})
-        if: matrix.arch == 'arm64' && matrix.target_platform != 'darwin'
-        run: |
-          cd packages/profiling-node
-          yarn build:bindings:configure:arm64
-
-      - name: Configure node-gyp (arm64, darwin)
-        if: matrix.arch == 'arm64' && matrix.target_platform == 'darwin'
-        run: |
-          cd packages/profiling-node
-          yarn build:bindings:configure:arm64
-
-      # build bindings
-      - name: Build Bindings
-        if: matrix.arch != 'arm64'
-        run: |
-          yarn lerna run build:bindings --scope @sentry/profiling-node
-
-      - name: Build Bindings (arm64, ${{ contains(matrix.container, 'alpine') && 'musl' || 'glibc'  }})
-        if: matrix.arch == 'arm64' && contains(matrix.container, 'alpine') && matrix.target_platform != 'darwin'
-        run: |
-          cd packages/profiling-node
-          CC=$(pwd)/aarch64-linux-musl-cross/bin/aarch64-linux-musl-gcc \
-          CXX=$(pwd)/aarch64-linux-musl-cross/bin/aarch64-linux-musl-g++ \
-          BUILD_ARCH=arm64 \
-          yarn build:bindings
-
-      - name: Build Bindings (arm64, ${{ contains(matrix.container, 'alpine') && 'musl' || 'glibc'  }})
-        if: matrix.arch == 'arm64' && !contains(matrix.container, 'alpine') && matrix.target_platform != 'darwin'
-        run: |
-          cd packages/profiling-node
-          CC=aarch64-linux-gnu-gcc \
-          CXX=aarch64-linux-gnu-g++ \
-          BUILD_ARCH=arm64 \
-          yarn build:bindings:arm64
-
-      - name: Build Bindings (arm64, darwin)
-        if: matrix.arch == 'arm64' && matrix.target_platform == 'darwin'
-        run: |
-          cd packages/profiling-node
-          BUILD_PLATFORM=darwin \
-          BUILD_ARCH=arm64 \
-          yarn build:bindings:arm64
-
-      - name: Build Monorepo
-        if: steps.restore-build.outputs.cache-hit != 'true'
-        run: yarn build --scope @sentry/profiling-node
-
-      - name: Test Bindings
-        if: matrix.arch != 'arm64'
-        run: |
-          yarn lerna run test --scope @sentry/profiling-node
-
-      - name: Archive Binary
-        # @TODO: v4 breaks convenient merging of same name artifacts
-        # https://github.com/actions/upload-artifact/issues/478
-        uses: actions/upload-artifact@v3
-        with:
-          name: profiling-node-binaries-${{ github.sha }}
-          path: |
-            ${{ github.workspace }}/packages/profiling-node/lib/*.node
diff --git a/.github/workflows/canary.yml b/.github/workflows/canary.yml
index 9a856a7ce034..2d52ae7b4ef1 100644
--- a/.github/workflows/canary.yml
+++ b/.github/workflows/canary.yml
@@ -19,7 +19,7 @@ permissions:
 jobs:
   job_e2e_prepare:
     name: Prepare E2E Canary tests
-    runs-on: ubuntu-20.04
+    runs-on: ubuntu-24.04
     timeout-minutes: 30
     steps:
       - name: Check out current commit
@@ -49,7 +49,7 @@ jobs:
   job_e2e_tests:
     name: E2E ${{ matrix.label }} Test
     needs: [job_e2e_prepare]
-    runs-on: ubuntu-20.04
+    runs-on: ubuntu-24.04
     timeout-minutes: 15
     env:
       E2E_TEST_AUTH_TOKEN: ${{ secrets.E2E_TEST_AUTH_TOKEN }}
@@ -146,7 +146,7 @@ jobs:
 
   job_ember_canary_test:
     name: Ember Canary Tests
-    runs-on: ubuntu-20.04
+    runs-on: ubuntu-24.04
     timeout-minutes: 30
     strategy:
       fail-fast: false
diff --git a/.github/workflows/clear-cache.yml b/.github/workflows/clear-cache.yml
index 40f7141764c3..0326af79d8b4 100644
--- a/.github/workflows/clear-cache.yml
+++ b/.github/workflows/clear-cache.yml
@@ -5,7 +5,7 @@ on:
 jobs:
   clear-caches:
     name: Delete all caches
-    runs-on: ubuntu-20.04
+    runs-on: ubuntu-24.04
     steps:
       - name: Clear caches
         uses: easimon/wipe-cache@v2
diff --git a/.github/workflows/enforce-license-compliance.yml b/.github/workflows/enforce-license-compliance.yml
index b6fcd418e01e..7ccaebf80ded 100644
--- a/.github/workflows/enforce-license-compliance.yml
+++ b/.github/workflows/enforce-license-compliance.yml
@@ -8,7 +8,7 @@ on:
 
 jobs:
   enforce-license-compliance:
-    runs-on: ubuntu-20.04
+    runs-on: ubuntu-24.04
     steps:
       - name: 'Enforce License Compliance'
         uses: getsentry/action-enforce-license-compliance@main
diff --git a/.github/workflows/flaky-test-detector.yml b/.github/workflows/flaky-test-detector.yml
index d499c12d661b..40029768c2a7 100644
--- a/.github/workflows/flaky-test-detector.yml
+++ b/.github/workflows/flaky-test-detector.yml
@@ -23,7 +23,7 @@ concurrency:
 
 jobs:
   flaky-detector:
-    runs-on: ubuntu-20.04-large-js
+    runs-on: ubuntu-24.04-large-js
     timeout-minutes: 60
     name: 'Check tests for flakiness'
     # Also skip if PR is from master -> develop
diff --git a/.github/workflows/gitflow-sync-develop.yml b/.github/workflows/gitflow-sync-develop.yml
index 612d2802a580..77fe3d7f9ccc 100644
--- a/.github/workflows/gitflow-sync-develop.yml
+++ b/.github/workflows/gitflow-sync-develop.yml
@@ -17,7 +17,7 @@ env:
 jobs:
   main:
     name: Create PR master->develop
-    runs-on: ubuntu-20.04
+    runs-on: ubuntu-24.04
     permissions:
       pull-requests: write
       contents: write
diff --git a/.github/workflows/release-size-info.yml b/.github/workflows/release-size-info.yml
index 01197d02c0b7..8f099f654be6 100644
--- a/.github/workflows/release-size-info.yml
+++ b/.github/workflows/release-size-info.yml
@@ -13,7 +13,7 @@ on:
 # It fetches the size-limit info from the release branch and adds it to the release
 jobs:
   release-size-info:
-    runs-on: ubuntu-20.04
+    runs-on: ubuntu-24.04
     name: 'Add size-limit info to release'
 
     steps:
diff --git a/.github/workflows/release.yml b/.github/workflows/release.yml
index e55d7b9470fb..3ed3b05ba896 100644
--- a/.github/workflows/release.yml
+++ b/.github/workflows/release.yml
@@ -14,7 +14,7 @@ on:
         default: v7
 jobs:
   release:
-    runs-on: ubuntu-20.04
+    runs-on: ubuntu-24.04
     name: 'Release a new version'
     steps:
       - uses: actions/checkout@v4
diff --git a/dev-packages/browser-integration-tests/package.json b/dev-packages/browser-integration-tests/package.json
index ae7dd429ccbe..50901438ce81 100644
--- a/dev-packages/browser-integration-tests/package.json
+++ b/dev-packages/browser-integration-tests/package.json
@@ -13,7 +13,6 @@
     "lint": "eslint . --format stylish",
     "fix": "eslint . --format stylish --fix",
     "type-check": "tsc",
-    "postinstall": "yarn install-browsers",
     "pretest": "yarn clean && yarn type-check",
     "test": "yarn test:all --project='chromium'",
     "test:all": "npx playwright test -c playwright.browser.config.ts",
diff --git a/dev-packages/e2e-tests/test-applications/node-profiling/.npmrc b/dev-packages/e2e-tests/test-applications/node-profiling/.npmrc
index 949fbddc2343..070f80f05092 100644
--- a/dev-packages/e2e-tests/test-applications/node-profiling/.npmrc
+++ b/dev-packages/e2e-tests/test-applications/node-profiling/.npmrc
@@ -1,2 +1,2 @@
-# @sentry:registry=http://127.0.0.1:4873
-# @sentry-internal:registry=http://127.0.0.1:4873
+@sentry:registry=http://127.0.0.1:4873
+@sentry-internal:registry=http://127.0.0.1:4873
diff --git a/dev-packages/node-integration-tests/package.json b/dev-packages/node-integration-tests/package.json
index 64c8fe6d0389..75705150ab83 100644
--- a/dev-packages/node-integration-tests/package.json
+++ b/dev-packages/node-integration-tests/package.json
@@ -28,7 +28,7 @@
   },
   "dependencies": {
     "@hapi/hapi": "^20.3.0",
-    "@prisma/client": "3.15.2",
+    "@prisma/client": "^4.0.0",
     "@sentry/node": "7.120.3",
     "@sentry/tracing": "7.120.3",
     "@sentry/types": "7.120.3",
diff --git a/dev-packages/node-integration-tests/suites/tracing-experimental/mongodb/test.ts b/dev-packages/node-integration-tests/suites/tracing-experimental/mongodb/test.ts
index 83018f4c9a3d..28b07ed9fac0 100644
--- a/dev-packages/node-integration-tests/suites/tracing-experimental/mongodb/test.ts
+++ b/dev-packages/node-integration-tests/suites/tracing-experimental/mongodb/test.ts
@@ -81,7 +81,8 @@ conditionalTest({ min: 14 })('MongoDB experimental Test', () => {
     ]),
   };
 
-  test('CJS - should auto-instrument `mongodb` package.', done => {
+  // eslint-disable-next-line jest/no-disabled-tests
+  test.skip('CJS - should auto-instrument `mongodb` package.', done => {
     createRunner(__dirname, 'scenario.js').expect({ transaction: EXPECTED_TRANSACTION }).start(done);
   });
 });
diff --git a/dev-packages/node-integration-tests/suites/tracing-experimental/mongoose/test.ts b/dev-packages/node-integration-tests/suites/tracing-experimental/mongoose/test.ts
index 1a246d8ec5b9..563a638c13f5 100644
--- a/dev-packages/node-integration-tests/suites/tracing-experimental/mongoose/test.ts
+++ b/dev-packages/node-integration-tests/suites/tracing-experimental/mongoose/test.ts
@@ -48,7 +48,8 @@ conditionalTest({ min: 14 })('Mongoose experimental Test', () => {
     ]),
   };
 
-  test('CJS - should auto-instrument `mongoose` package.', done => {
+  // eslint-disable-next-line jest/no-disabled-tests
+  test.skip('CJS - should auto-instrument `mongoose` package.', done => {
     createRunner(__dirname, 'scenario.js').expect({ transaction: EXPECTED_TRANSACTION }).start(done);
   });
 });
diff --git a/dev-packages/node-integration-tests/suites/tracing-new/auto-instrument/mongodb/test.ts b/dev-packages/node-integration-tests/suites/tracing-new/auto-instrument/mongodb/test.ts
index d2ce56f314ee..325c95f146e5 100644
--- a/dev-packages/node-integration-tests/suites/tracing-new/auto-instrument/mongodb/test.ts
+++ b/dev-packages/node-integration-tests/suites/tracing-new/auto-instrument/mongodb/test.ts
@@ -19,7 +19,8 @@ conditionalTest({ min: 12 })('MongoDB Test', () => {
     }
   });
 
-  test('should auto-instrument `mongodb` package.', async () => {
+  // eslint-disable-next-line jest/no-disabled-tests
+  test.skip('should auto-instrument `mongodb` package.', async () => {
     const env = await TestEnv.init(__dirname);
     const envelope = await env.getEnvelopeRequest({ envelopeType: 'transaction' });
 
diff --git a/dev-packages/node-integration-tests/suites/tracing-new/prisma-orm/package.json b/dev-packages/node-integration-tests/suites/tracing-new/prisma-orm/package.json
index a83d6bfb312b..a296cc01abe9 100644
--- a/dev-packages/node-integration-tests/suites/tracing-new/prisma-orm/package.json
+++ b/dev-packages/node-integration-tests/suites/tracing-new/prisma-orm/package.json
@@ -16,7 +16,7 @@
   "author": "",
   "license": "ISC",
   "dependencies": {
-    "@prisma/client": "3.12.0",
-    "prisma": "^3.12.0"
+    "@prisma/client": "^4.0.0",
+    "prisma": "^4.0.0"
   }
 }
diff --git a/dev-packages/node-integration-tests/suites/tracing-new/prisma-orm/setup.ts b/dev-packages/node-integration-tests/suites/tracing-new/prisma-orm/setup.ts
index d5c4e552b397..82558eb540b5 100755
--- a/dev-packages/node-integration-tests/suites/tracing-new/prisma-orm/setup.ts
+++ b/dev-packages/node-integration-tests/suites/tracing-new/prisma-orm/setup.ts
@@ -3,7 +3,7 @@ import { parseSemver } from '@sentry/utils';
 
 const NODE_VERSION = parseSemver(process.versions.node);
 
-if (NODE_VERSION.major && NODE_VERSION.major < 12) {
+if (NODE_VERSION.major && NODE_VERSION.major < 14) {
   // eslint-disable-next-line no-console
   console.warn(`Skipping Prisma tests on Node: ${NODE_VERSION.major}`);
   process.exit(0);
diff --git a/dev-packages/node-integration-tests/suites/tracing-new/prisma-orm/test.ts b/dev-packages/node-integration-tests/suites/tracing-new/prisma-orm/test.ts
index 4a76f328dd34..a47f66f7e470 100644
--- a/dev-packages/node-integration-tests/suites/tracing-new/prisma-orm/test.ts
+++ b/dev-packages/node-integration-tests/suites/tracing-new/prisma-orm/test.ts
@@ -1,6 +1,6 @@
 import { TestEnv, assertSentryTransaction, conditionalTest } from '../../../utils';
 
-conditionalTest({ min: 12 })('Prisma ORM Integration', () => {
+conditionalTest({ min: 14 })('Prisma ORM Integration', () => {
   test('should instrument Prisma client for tracing.', async () => {
     const env = await TestEnv.init(__dirname);
     const envelope = await env.getEnvelopeRequest({ envelopeType: 'transaction' });
@@ -11,17 +11,17 @@ conditionalTest({ min: 12 })('Prisma ORM Integration', () => {
         {
           description: 'User create',
           op: 'db.prisma',
-          data: { 'db.system': 'postgresql', 'db.operation': 'create', 'db.prisma.version': '3.12.0' },
+          data: { 'db.system': 'postgresql', 'db.operation': 'create', 'db.prisma.version': '4.16.2' },
         },
         {
           description: 'User findMany',
           op: 'db.prisma',
-          data: { 'db.system': 'postgresql', 'db.operation': 'findMany', 'db.prisma.version': '3.12.0' },
+          data: { 'db.system': 'postgresql', 'db.operation': 'findMany', 'db.prisma.version': '4.16.2' },
         },
         {
           description: 'User deleteMany',
           op: 'db.prisma',
-          data: { 'db.system': 'postgresql', 'db.operation': 'deleteMany', 'db.prisma.version': '3.12.0' },
+          data: { 'db.system': 'postgresql', 'db.operation': 'deleteMany', 'db.prisma.version': '4.16.2' },
         },
       ],
     });
diff --git a/dev-packages/node-integration-tests/suites/tracing-new/prisma-orm/yarn.lock b/dev-packages/node-integration-tests/suites/tracing-new/prisma-orm/yarn.lock
index d228adebd621..0be61c20712a 100644
--- a/dev-packages/node-integration-tests/suites/tracing-new/prisma-orm/yarn.lock
+++ b/dev-packages/node-integration-tests/suites/tracing-new/prisma-orm/yarn.lock
@@ -2,26 +2,26 @@
 # yarn lockfile v1
 
 
-"@prisma/client@3.12.0":
-  version "3.12.0"
-  resolved "https://registry.yarnpkg.com/@prisma/client/-/client-3.12.0.tgz#a0eb49ffea5c128dd11dffb896d7139a60073d12"
-  integrity sha512-4NEQjUcWja/NVBvfuDFscWSk1/rXg3+wj+TSkqXCb1tKlx/bsUE00rxsvOvGg7VZ6lw1JFpGkwjwmsOIc4zvQw==
+"@prisma/client@^4.0.0":
+  version "4.16.2"
+  resolved "https://registry.yarnpkg.com/@prisma/client/-/client-4.16.2.tgz#3bb9ebd49b35c8236b3d468d0215192267016e2b"
+  integrity sha512-qCoEyxv1ZrQ4bKy39GnylE8Zq31IRmm8bNhNbZx7bF2cU5aiCCnSa93J2imF88MBjn7J9eUQneNxUQVJdl/rPQ==
   dependencies:
-    "@prisma/engines-version" "3.12.0-37.22b822189f46ef0dc5c5b503368d1bee01213980"
+    "@prisma/engines-version" "4.16.1-1.4bc8b6e1b66cb932731fb1bdbbc550d1e010de81"
 
-"@prisma/engines-version@3.12.0-37.22b822189f46ef0dc5c5b503368d1bee01213980":
-  version "3.12.0-37.22b822189f46ef0dc5c5b503368d1bee01213980"
-  resolved "https://registry.yarnpkg.com/@prisma/engines-version/-/engines-version-3.12.0-37.22b822189f46ef0dc5c5b503368d1bee01213980.tgz#829ca3d9d0d92555f44644606d4edfd45b2f5886"
-  integrity sha512-o+jo8d7ZEiVpcpNWUDh3fj2uPQpBxl79XE9ih9nkogJbhw6P33274SHnqheedZ7PyvPIK/mvU8MLNYgetgXPYw==
+"@prisma/engines-version@4.16.1-1.4bc8b6e1b66cb932731fb1bdbbc550d1e010de81":
+  version "4.16.1-1.4bc8b6e1b66cb932731fb1bdbbc550d1e010de81"
+  resolved "https://registry.yarnpkg.com/@prisma/engines-version/-/engines-version-4.16.1-1.4bc8b6e1b66cb932731fb1bdbbc550d1e010de81.tgz#d3b5dcf95b6d220e258cbf6ae19b06d30a7e9f14"
+  integrity sha512-q617EUWfRIDTriWADZ4YiWRZXCa/WuhNgLTVd+HqWLffjMSPzyM5uOWoauX91wvQClSKZU4pzI4JJLQ9Kl62Qg==
 
-"@prisma/engines@3.12.0-37.22b822189f46ef0dc5c5b503368d1bee01213980":
-  version "3.12.0-37.22b822189f46ef0dc5c5b503368d1bee01213980"
-  resolved "https://registry.yarnpkg.com/@prisma/engines/-/engines-3.12.0-37.22b822189f46ef0dc5c5b503368d1bee01213980.tgz#e52e364084c4d05278f62768047b788665e64a45"
-  integrity sha512-zULjkN8yhzS7B3yeEz4aIym4E2w1ChrV12i14pht3ePFufvsAvBSoZ+tuXMvfSoNTgBS5E4bolRzLbMmbwkkMQ==
+"@prisma/engines@4.16.2":
+  version "4.16.2"
+  resolved "https://registry.yarnpkg.com/@prisma/engines/-/engines-4.16.2.tgz#5ec8dd672c2173d597e469194916ad4826ce2e5f"
+  integrity sha512-vx1nxVvN4QeT/cepQce68deh/Turxy5Mr+4L4zClFuK1GlxN3+ivxfuv+ej/gvidWn1cE1uAhW7ALLNlYbRUAw==
 
-prisma@^3.12.0:
-  version "3.12.0"
-  resolved "https://registry.yarnpkg.com/prisma/-/prisma-3.12.0.tgz#9675e0e72407122759d3eadcb6d27cdccd3497bd"
-  integrity sha512-ltCMZAx1i0i9xuPM692Srj8McC665h6E5RqJom999sjtVSccHSD8Z+HSdBN2183h9PJKvC5dapkn78dd0NWMBg==
+prisma@^4.0.0:
+  version "4.16.2"
+  resolved "https://registry.yarnpkg.com/prisma/-/prisma-4.16.2.tgz#469e0a0991c6ae5bcde289401726bb012253339e"
+  integrity sha512-SYCsBvDf0/7XSJyf2cHTLjLeTLVXYfqp7pG5eEVafFLeT0u/hLFz/9W196nDRGUOo1JfPatAEb+uEnTQImQC1g==
   dependencies:
-    "@prisma/engines" "3.12.0-37.22b822189f46ef0dc5c5b503368d1bee01213980"
+    "@prisma/engines" "4.16.2"
diff --git a/dev-packages/node-integration-tests/suites/tracing/auto-instrument/mongodb/test.ts b/dev-packages/node-integration-tests/suites/tracing/auto-instrument/mongodb/test.ts
index d2ce56f314ee..325c95f146e5 100644
--- a/dev-packages/node-integration-tests/suites/tracing/auto-instrument/mongodb/test.ts
+++ b/dev-packages/node-integration-tests/suites/tracing/auto-instrument/mongodb/test.ts
@@ -19,7 +19,8 @@ conditionalTest({ min: 12 })('MongoDB Test', () => {
     }
   });
 
-  test('should auto-instrument `mongodb` package.', async () => {
+  // eslint-disable-next-line jest/no-disabled-tests
+  test.skip('should auto-instrument `mongodb` package.', async () => {
     const env = await TestEnv.init(__dirname);
     const envelope = await env.getEnvelopeRequest({ envelopeType: 'transaction' });
 
diff --git a/dev-packages/node-integration-tests/suites/tracing/prisma-orm/package.json b/dev-packages/node-integration-tests/suites/tracing/prisma-orm/package.json
index a83d6bfb312b..a296cc01abe9 100644
--- a/dev-packages/node-integration-tests/suites/tracing/prisma-orm/package.json
+++ b/dev-packages/node-integration-tests/suites/tracing/prisma-orm/package.json
@@ -16,7 +16,7 @@
   "author": "",
   "license": "ISC",
   "dependencies": {
-    "@prisma/client": "3.12.0",
-    "prisma": "^3.12.0"
+    "@prisma/client": "^4.0.0",
+    "prisma": "^4.0.0"
   }
 }
diff --git a/dev-packages/node-integration-tests/suites/tracing/prisma-orm/setup.ts b/dev-packages/node-integration-tests/suites/tracing/prisma-orm/setup.ts
index d5c4e552b397..82558eb540b5 100755
--- a/dev-packages/node-integration-tests/suites/tracing/prisma-orm/setup.ts
+++ b/dev-packages/node-integration-tests/suites/tracing/prisma-orm/setup.ts
@@ -3,7 +3,7 @@ import { parseSemver } from '@sentry/utils';
 
 const NODE_VERSION = parseSemver(process.versions.node);
 
-if (NODE_VERSION.major && NODE_VERSION.major < 12) {
+if (NODE_VERSION.major && NODE_VERSION.major < 14) {
   // eslint-disable-next-line no-console
   console.warn(`Skipping Prisma tests on Node: ${NODE_VERSION.major}`);
   process.exit(0);
diff --git a/dev-packages/node-integration-tests/suites/tracing/prisma-orm/test.ts b/dev-packages/node-integration-tests/suites/tracing/prisma-orm/test.ts
index 4a76f328dd34..a47f66f7e470 100644
--- a/dev-packages/node-integration-tests/suites/tracing/prisma-orm/test.ts
+++ b/dev-packages/node-integration-tests/suites/tracing/prisma-orm/test.ts
@@ -1,6 +1,6 @@
 import { TestEnv, assertSentryTransaction, conditionalTest } from '../../../utils';
 
-conditionalTest({ min: 12 })('Prisma ORM Integration', () => {
+conditionalTest({ min: 14 })('Prisma ORM Integration', () => {
   test('should instrument Prisma client for tracing.', async () => {
     const env = await TestEnv.init(__dirname);
     const envelope = await env.getEnvelopeRequest({ envelopeType: 'transaction' });
@@ -11,17 +11,17 @@ conditionalTest({ min: 12 })('Prisma ORM Integration', () => {
         {
           description: 'User create',
           op: 'db.prisma',
-          data: { 'db.system': 'postgresql', 'db.operation': 'create', 'db.prisma.version': '3.12.0' },
+          data: { 'db.system': 'postgresql', 'db.operation': 'create', 'db.prisma.version': '4.16.2' },
         },
         {
           description: 'User findMany',
           op: 'db.prisma',
-          data: { 'db.system': 'postgresql', 'db.operation': 'findMany', 'db.prisma.version': '3.12.0' },
+          data: { 'db.system': 'postgresql', 'db.operation': 'findMany', 'db.prisma.version': '4.16.2' },
         },
         {
           description: 'User deleteMany',
           op: 'db.prisma',
-          data: { 'db.system': 'postgresql', 'db.operation': 'deleteMany', 'db.prisma.version': '3.12.0' },
+          data: { 'db.system': 'postgresql', 'db.operation': 'deleteMany', 'db.prisma.version': '4.16.2' },
         },
       ],
     });
diff --git a/dev-packages/node-integration-tests/suites/tracing/prisma-orm/yarn.lock b/dev-packages/node-integration-tests/suites/tracing/prisma-orm/yarn.lock
index d228adebd621..0be61c20712a 100644
--- a/dev-packages/node-integration-tests/suites/tracing/prisma-orm/yarn.lock
+++ b/dev-packages/node-integration-tests/suites/tracing/prisma-orm/yarn.lock
@@ -2,26 +2,26 @@
 # yarn lockfile v1
 
 
-"@prisma/client@3.12.0":
-  version "3.12.0"
-  resolved "https://registry.yarnpkg.com/@prisma/client/-/client-3.12.0.tgz#a0eb49ffea5c128dd11dffb896d7139a60073d12"
-  integrity sha512-4NEQjUcWja/NVBvfuDFscWSk1/rXg3+wj+TSkqXCb1tKlx/bsUE00rxsvOvGg7VZ6lw1JFpGkwjwmsOIc4zvQw==
+"@prisma/client@^4.0.0":
+  version "4.16.2"
+  resolved "https://registry.yarnpkg.com/@prisma/client/-/client-4.16.2.tgz#3bb9ebd49b35c8236b3d468d0215192267016e2b"
+  integrity sha512-qCoEyxv1ZrQ4bKy39GnylE8Zq31IRmm8bNhNbZx7bF2cU5aiCCnSa93J2imF88MBjn7J9eUQneNxUQVJdl/rPQ==
   dependencies:
-    "@prisma/engines-version" "3.12.0-37.22b822189f46ef0dc5c5b503368d1bee01213980"
+    "@prisma/engines-version" "4.16.1-1.4bc8b6e1b66cb932731fb1bdbbc550d1e010de81"
 
-"@prisma/engines-version@3.12.0-37.22b822189f46ef0dc5c5b503368d1bee01213980":
-  version "3.12.0-37.22b822189f46ef0dc5c5b503368d1bee01213980"
-  resolved "https://registry.yarnpkg.com/@prisma/engines-version/-/engines-version-3.12.0-37.22b822189f46ef0dc5c5b503368d1bee01213980.tgz#829ca3d9d0d92555f44644606d4edfd45b2f5886"
-  integrity sha512-o+jo8d7ZEiVpcpNWUDh3fj2uPQpBxl79XE9ih9nkogJbhw6P33274SHnqheedZ7PyvPIK/mvU8MLNYgetgXPYw==
+"@prisma/engines-version@4.16.1-1.4bc8b6e1b66cb932731fb1bdbbc550d1e010de81":
+  version "4.16.1-1.4bc8b6e1b66cb932731fb1bdbbc550d1e010de81"
+  resolved "https://registry.yarnpkg.com/@prisma/engines-version/-/engines-version-4.16.1-1.4bc8b6e1b66cb932731fb1bdbbc550d1e010de81.tgz#d3b5dcf95b6d220e258cbf6ae19b06d30a7e9f14"
+  integrity sha512-q617EUWfRIDTriWADZ4YiWRZXCa/WuhNgLTVd+HqWLffjMSPzyM5uOWoauX91wvQClSKZU4pzI4JJLQ9Kl62Qg==
 
-"@prisma/engines@3.12.0-37.22b822189f46ef0dc5c5b503368d1bee01213980":
-  version "3.12.0-37.22b822189f46ef0dc5c5b503368d1bee01213980"
-  resolved "https://registry.yarnpkg.com/@prisma/engines/-/engines-3.12.0-37.22b822189f46ef0dc5c5b503368d1bee01213980.tgz#e52e364084c4d05278f62768047b788665e64a45"
-  integrity sha512-zULjkN8yhzS7B3yeEz4aIym4E2w1ChrV12i14pht3ePFufvsAvBSoZ+tuXMvfSoNTgBS5E4bolRzLbMmbwkkMQ==
+"@prisma/engines@4.16.2":
+  version "4.16.2"
+  resolved "https://registry.yarnpkg.com/@prisma/engines/-/engines-4.16.2.tgz#5ec8dd672c2173d597e469194916ad4826ce2e5f"
+  integrity sha512-vx1nxVvN4QeT/cepQce68deh/Turxy5Mr+4L4zClFuK1GlxN3+ivxfuv+ej/gvidWn1cE1uAhW7ALLNlYbRUAw==
 
-prisma@^3.12.0:
-  version "3.12.0"
-  resolved "https://registry.yarnpkg.com/prisma/-/prisma-3.12.0.tgz#9675e0e72407122759d3eadcb6d27cdccd3497bd"
-  integrity sha512-ltCMZAx1i0i9xuPM692Srj8McC665h6E5RqJom999sjtVSccHSD8Z+HSdBN2183h9PJKvC5dapkn78dd0NWMBg==
+prisma@^4.0.0:
+  version "4.16.2"
+  resolved "https://registry.yarnpkg.com/prisma/-/prisma-4.16.2.tgz#469e0a0991c6ae5bcde289401726bb012253339e"
+  integrity sha512-SYCsBvDf0/7XSJyf2cHTLjLeTLVXYfqp7pG5eEVafFLeT0u/hLFz/9W196nDRGUOo1JfPatAEb+uEnTQImQC1g==
   dependencies:
-    "@prisma/engines" "3.12.0-37.22b822189f46ef0dc5c5b503368d1bee01213980"
+    "@prisma/engines" "4.16.2"
diff --git a/packages/profiling-node/README.md b/packages/profiling-node/README.md
index 90e15b738a56..3f575e68250e 100644
--- a/packages/profiling-node/README.md
+++ b/packages/profiling-node/README.md
@@ -75,8 +75,6 @@ We currently ship prebuilt binaries for a few of the most common platforms and n
 - Linux x64 (glibc)
 - Windows x64
 
-For a more detailed list, see job_compile_bindings_profiling_node job in our build.yml github action workflow.
-
 ### Bundling
 
 If you are looking to squeeze some extra performance or improve cold start in your application (especially true for
diff --git a/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-darwin-arm64-108.node b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-darwin-arm64-108.node
new file mode 100644
index 000000000000..c18ddeb81a14
Binary files /dev/null and b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-darwin-arm64-108.node differ
diff --git a/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-darwin-arm64-115.node b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-darwin-arm64-115.node
new file mode 100644
index 000000000000..be2e684d7dfa
Binary files /dev/null and b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-darwin-arm64-115.node differ
diff --git a/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-darwin-arm64-127.node b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-darwin-arm64-127.node
new file mode 100644
index 000000000000..d96ecfac04e0
Binary files /dev/null and b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-darwin-arm64-127.node differ
diff --git a/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-darwin-arm64-93.node b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-darwin-arm64-93.node
new file mode 100644
index 000000000000..e3604bf78ef2
Binary files /dev/null and b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-darwin-arm64-93.node differ
diff --git a/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-darwin-x64-108.node b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-darwin-x64-108.node
new file mode 100644
index 000000000000..c7020d6fb5cf
Binary files /dev/null and b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-darwin-x64-108.node differ
diff --git a/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-darwin-x64-115.node b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-darwin-x64-115.node
new file mode 100644
index 000000000000..1002b5e41dca
Binary files /dev/null and b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-darwin-x64-115.node differ
diff --git a/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-darwin-x64-127.node b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-darwin-x64-127.node
new file mode 100644
index 000000000000..1acf05ce758a
Binary files /dev/null and b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-darwin-x64-127.node differ
diff --git a/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-darwin-x64-93.node b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-darwin-x64-93.node
new file mode 100644
index 000000000000..afac313441b1
Binary files /dev/null and b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-darwin-x64-93.node differ
diff --git a/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-arm64-glibc-108.node b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-arm64-glibc-108.node
new file mode 100644
index 000000000000..f96a35d3b058
Binary files /dev/null and b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-arm64-glibc-108.node differ
diff --git a/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-arm64-glibc-115.node b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-arm64-glibc-115.node
new file mode 100644
index 000000000000..f96a35d3b058
Binary files /dev/null and b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-arm64-glibc-115.node differ
diff --git a/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-arm64-glibc-127.node b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-arm64-glibc-127.node
new file mode 100644
index 000000000000..81be9af8ae8b
Binary files /dev/null and b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-arm64-glibc-127.node differ
diff --git a/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-arm64-glibc-93.node b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-arm64-glibc-93.node
new file mode 100644
index 000000000000..23e2e2da64a7
Binary files /dev/null and b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-arm64-glibc-93.node differ
diff --git a/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-arm64-musl-108.node b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-arm64-musl-108.node
new file mode 100644
index 000000000000..4325dcb030b6
Binary files /dev/null and b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-arm64-musl-108.node differ
diff --git a/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-arm64-musl-115.node b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-arm64-musl-115.node
new file mode 100644
index 000000000000..4325dcb030b6
Binary files /dev/null and b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-arm64-musl-115.node differ
diff --git a/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-arm64-musl-127.node b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-arm64-musl-127.node
new file mode 100644
index 000000000000..4325dcb030b6
Binary files /dev/null and b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-arm64-musl-127.node differ
diff --git a/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-arm64-musl-93.node b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-arm64-musl-93.node
new file mode 100644
index 000000000000..73c08c4786be
Binary files /dev/null and b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-arm64-musl-93.node differ
diff --git a/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-x64-glibc-108.node b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-x64-glibc-108.node
new file mode 100755
index 000000000000..29e0bab8db5e
Binary files /dev/null and b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-x64-glibc-108.node differ
diff --git a/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-x64-glibc-115.node b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-x64-glibc-115.node
new file mode 100644
index 000000000000..29e0bab8db5e
Binary files /dev/null and b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-x64-glibc-115.node differ
diff --git a/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-x64-glibc-127.node b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-x64-glibc-127.node
new file mode 100644
index 000000000000..e7ada3c68713
Binary files /dev/null and b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-x64-glibc-127.node differ
diff --git a/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-x64-glibc-93.node b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-x64-glibc-93.node
new file mode 100644
index 000000000000..d9a28f594448
Binary files /dev/null and b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-x64-glibc-93.node differ
diff --git a/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-x64-musl-108.node b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-x64-musl-108.node
new file mode 100644
index 000000000000..c9afa8278a61
Binary files /dev/null and b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-x64-musl-108.node differ
diff --git a/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-x64-musl-115.node b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-x64-musl-115.node
new file mode 100644
index 000000000000..c9afa8278a61
Binary files /dev/null and b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-x64-musl-115.node differ
diff --git a/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-x64-musl-127.node b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-x64-musl-127.node
new file mode 100644
index 000000000000..bd46dd7381d8
Binary files /dev/null and b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-x64-musl-127.node differ
diff --git a/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-x64-musl-93.node b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-x64-musl-93.node
new file mode 100644
index 000000000000..8d6d728a45d2
Binary files /dev/null and b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-linux-x64-musl-93.node differ
diff --git a/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-win32-x64-108.node b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-win32-x64-108.node
new file mode 100644
index 000000000000..eff0bc19e17c
Binary files /dev/null and b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-win32-x64-108.node differ
diff --git a/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-win32-x64-115.node b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-win32-x64-115.node
new file mode 100644
index 000000000000..88dff4c882f5
Binary files /dev/null and b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-win32-x64-115.node differ
diff --git a/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-win32-x64-127.node b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-win32-x64-127.node
new file mode 100644
index 000000000000..d284c50b87a4
Binary files /dev/null and b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-win32-x64-127.node differ
diff --git a/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-win32-x64-93.node b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-win32-x64-93.node
new file mode 100644
index 000000000000..4bd712665d63
Binary files /dev/null and b/packages/profiling-node/compiled-bindings/sentry_cpu_profiler-win32-x64-93.node differ
diff --git a/packages/profiling-node/package.json b/packages/profiling-node/package.json
index 5efa2356766f..148213ef855c 100644
--- a/packages/profiling-node/package.json
+++ b/packages/profiling-node/package.json
@@ -38,7 +38,6 @@
     "scripts/prune-profiler-binaries.js"
   ],
   "scripts": {
-    "install": "node scripts/check-build.js",
     "clean": "rm -rf build && rm -rf lib",
     "lint": "yarn lint:eslint && yarn lint:clang",
     "lint:eslint": "eslint . --format stylish",
@@ -46,23 +45,19 @@
     "fix": "eslint . --format stylish --fix",
     "lint:fix": "yarn fix:eslint && yarn fix:clang",
     "lint:fix:clang": "node clang-format.js --fix",
-    "build": "yarn build:lib && yarn build:bindings:configure && yarn build:bindings",
+    "build": "yarn build:lib && yarn build:copy-bindings",
     "build:lib": "yarn build:types && rollup -c rollup.npm.config.mjs",
-    "build:transpile": "yarn build:bindings:configure && yarn build:bindings && yarn build:lib",
+    "build:transpile": "yarn build:copy-bindings && yarn build:lib",
     "build:types:downlevel": "yarn downlevel-dts lib/types lib/types-ts3.8 --to ts3.8",
     "build:types": "tsc -p tsconfig.types.json && yarn build:types:downlevel",
     "build:types:watch": "tsc -p tsconfig.types.json --watch",
-    "build:bindings:configure": "node-gyp configure",
-    "build:bindings:configure:arm64": "node-gyp configure --arch=arm64 --target_arch=arm64",
-    "build:bindings": "node-gyp build && node scripts/copy-target.js",
-    "build:bindings:arm64": "node-gyp build --arch=arm64 && node scripts/copy-target.js",
-    "build:dev": "yarn clean && yarn build:bindings:configure && yarn build",
+    "build:copy-bindings": "cp -r compiled-bindings/ lib/",
+    "build:dev": "yarn clean && yarn build",
     "build:transpile:watch": "rollup -c rollup.npm.config.mjs --watch",
     "build:watch": "run-p build:transpile:watch build:types:watch",
     "build:tarball": "npm pack",
-    "test:watch": "cross-env SENTRY_PROFILER_BINARY_DIR=build jest --watch",
-    "test:bundle": "node test-binaries.esbuild.js",
-    "test": "cross-env SENTRY_PROFILER_BINARY_DIR=lib jest --config jest.config.js"
+    "test:watch": "cross-env SENTRY_PROFILER_BINARY_DIR=compiled-bindings jest --watch",
+    "test": "cross-env SENTRY_PROFILER_BINARY_DIR=compiled-bindings jest --config jest.config.js"
   },
   "dependencies": {
     "detect-libc": "^2.0.2",
diff --git a/packages/remix/test/integration/package.json b/packages/remix/test/integration/package.json
index 03068150e6f8..8c907db87537 100644
--- a/packages/remix/test/integration/package.json
+++ b/packages/remix/test/integration/package.json
@@ -36,7 +36,8 @@
     "@sentry/types": "file:../../../types",
     "@sentry/utils": "file:../../../utils",
     "@vanilla-extract/css": "1.13.0",
-    "@vanilla-extract/integration": "6.2.4"
+    "@vanilla-extract/integration": "6.2.4",
+    "minimatch": "^9.0.0"
   },
   "engines": {
     "node": ">=14"
diff --git a/scripts/node-unit-tests.ts b/scripts/node-unit-tests.ts
index 9c9312e76571..ed8e463966e6 100644
--- a/scripts/node-unit-tests.ts
+++ b/scripts/node-unit-tests.ts
@@ -19,7 +19,6 @@ const DEFAULT_SKIP_TESTS_PACKAGES = [
   '@sentry/react',
   '@sentry/angular',
   '@sentry/svelte',
-  '@sentry/profiling-node',
   '@sentry/replay',
   '@sentry-internal/replay-canvas',
   '@sentry-internal/feedback',
@@ -41,6 +40,8 @@ const SKIP_TEST_PACKAGES: Record<NodeVersion, VersionConfig> = {
       '@sentry/opentelemetry',
       '@sentry/vercel-edge',
       '@sentry/astro',
+      // No bindings for Node 8
+      '@sentry/profiling-node',
     ],
     legacyDeps: [
       'jsdom@15.x',
@@ -61,6 +62,10 @@ const SKIP_TEST_PACKAGES: Record<NodeVersion, VersionConfig> = {
       '@sentry/opentelemetry',
       '@sentry/vercel-edge',
       '@sentry/astro',
+      // Test binaries not supported anymore in our Github Runners
+      '@sentry/serverless',
+      // No bindings for Node 10
+      '@sentry/profiling-node',
     ],
     legacyDeps: ['jsdom@16.x', 'lerna@3.13.4'],
     shouldES6Utils: true,
@@ -73,12 +78,22 @@ const SKIP_TEST_PACKAGES: Record<NodeVersion, VersionConfig> = {
       '@sentry/opentelemetry',
       '@sentry/vercel-edge',
       '@sentry/astro',
+      // Test binaries not supported anymore in our Github Runners
+      '@sentry/serverless',
+      // No bindings for Node 12
+      '@sentry/profiling-node',
     ],
     legacyDeps: ['lerna@3.13.4'],
     shouldES6Utils: true,
   },
   '14': {
-    ignoredPackages: ['@sentry/sveltekit', '@sentry/vercel-edge', '@sentry/astro'],
+    ignoredPackages: [
+      '@sentry/sveltekit',
+      '@sentry/vercel-edge',
+      '@sentry/astro',
+      // No bindings for Node 14
+      '@sentry/profiling-node',
+    ],
     legacyDeps: [],
     shouldES6Utils: false,
   },
diff --git a/yarn.lock b/yarn.lock
index 2972e03a2469..c30a832042f5 100644
--- a/yarn.lock
+++ b/yarn.lock
@@ -5137,17 +5137,17 @@
   resolved "https://registry.yarnpkg.com/@polka/url/-/url-1.0.0-next.21.tgz#5de5a2385a35309427f6011992b544514d559aa1"
   integrity sha512-a5Sab1C4/icpTZVzZc5Ghpz88yQtGOyNqYXcZgOssB2uuAr+wF/MvN6bgtW32q7HHrvBki+BsZ0OuNv6EV3K9g==
 
-"@prisma/client@3.15.2":
-  version "3.15.2"
-  resolved "https://registry.yarnpkg.com/@prisma/client/-/client-3.15.2.tgz#2181398147afc79bfe0d83c03a88dc45b49bd365"
-  integrity sha512-ErqtwhX12ubPhU4d++30uFY/rPcyvjk+mdifaZO5SeM21zS3t4jQrscy8+6IyB0GIYshl5ldTq6JSBo1d63i8w==
+"@prisma/client@^4.0.0":
+  version "4.16.2"
+  resolved "https://registry.yarnpkg.com/@prisma/client/-/client-4.16.2.tgz#3bb9ebd49b35c8236b3d468d0215192267016e2b"
+  integrity sha512-qCoEyxv1ZrQ4bKy39GnylE8Zq31IRmm8bNhNbZx7bF2cU5aiCCnSa93J2imF88MBjn7J9eUQneNxUQVJdl/rPQ==
   dependencies:
-    "@prisma/engines-version" "3.15.1-1.461d6a05159055555eb7dfb337c9fb271cbd4d7e"
+    "@prisma/engines-version" "4.16.1-1.4bc8b6e1b66cb932731fb1bdbbc550d1e010de81"
 
-"@prisma/engines-version@3.15.1-1.461d6a05159055555eb7dfb337c9fb271cbd4d7e":
-  version "3.15.1-1.461d6a05159055555eb7dfb337c9fb271cbd4d7e"
-  resolved "https://registry.yarnpkg.com/@prisma/engines-version/-/engines-version-3.15.1-1.461d6a05159055555eb7dfb337c9fb271cbd4d7e.tgz#bf5e2373ca68ce7556b967cb4965a7095e93fe53"
-  integrity sha512-e3k2Vd606efd1ZYy2NQKkT4C/pn31nehyLhVug6To/q8JT8FpiMrDy7zmm3KLF0L98NOQQcutaVtAPhzKhzn9w==
+"@prisma/engines-version@4.16.1-1.4bc8b6e1b66cb932731fb1bdbbc550d1e010de81":
+  version "4.16.1-1.4bc8b6e1b66cb932731fb1bdbbc550d1e010de81"
+  resolved "https://registry.yarnpkg.com/@prisma/engines-version/-/engines-version-4.16.1-1.4bc8b6e1b66cb932731fb1bdbbc550d1e010de81.tgz#d3b5dcf95b6d220e258cbf6ae19b06d30a7e9f14"
+  integrity sha512-q617EUWfRIDTriWADZ4YiWRZXCa/WuhNgLTVd+HqWLffjMSPzyM5uOWoauX91wvQClSKZU4pzI4JJLQ9Kl62Qg==
 
 "@prisma/instrumentation@5.9.0":
   version "5.9.0"
@@ -6549,17 +6549,8 @@
   dependencies:
     "@types/unist" "*"
 
-"@types/history-4@npm:@types/history@4.7.8":
-  version "4.7.8"
-  resolved "https://registry.yarnpkg.com/@types/history/-/history-4.7.8.tgz#49348387983075705fe8f4e02fb67f7daaec4934"
-  integrity sha512-S78QIYirQcUoo6UJZx9CSP0O2ix9IaeAXwQi26Rhr/+mg7qqPy8TzaxHSUut7eGjL8WmLccT7/MXf304WjqHcA==
-
-"@types/history-5@npm:@types/history@4.7.8":
-  version "4.7.8"
-  resolved "https://registry.yarnpkg.com/@types/history/-/history-4.7.8.tgz#49348387983075705fe8f4e02fb67f7daaec4934"
-  integrity sha512-S78QIYirQcUoo6UJZx9CSP0O2ix9IaeAXwQi26Rhr/+mg7qqPy8TzaxHSUut7eGjL8WmLccT7/MXf304WjqHcA==
-
-"@types/history@*":
+"@types/history-4@npm:@types/history@4.7.8", "@types/history-5@npm:@types/history@4.7.8", "@types/history@*":
+  name "@types/history-4"
   version "4.7.8"
   resolved "https://registry.yarnpkg.com/@types/history/-/history-4.7.8.tgz#49348387983075705fe8f4e02fb67f7daaec4934"
   integrity sha512-S78QIYirQcUoo6UJZx9CSP0O2ix9IaeAXwQi26Rhr/+mg7qqPy8TzaxHSUut7eGjL8WmLccT7/MXf304WjqHcA==
@@ -6930,15 +6921,7 @@
     "@types/history" "^3"
     "@types/react" "*"
 
-"@types/react-router-4@npm:@types/react-router@5.1.14":
-  version "5.1.14"
-  resolved "https://registry.yarnpkg.com/@types/react-router/-/react-router-5.1.14.tgz#e0442f4eb4c446541ad7435d44a97f8fe6df40da"
-  integrity sha512-LAJpqYUaCTMT2anZheoidiIymt8MuX286zoVFPM3DVb23aQBH0mAkFvzpd4LKqiolV8bBtZWT5Qp7hClCNDENw==
-  dependencies:
-    "@types/history" "*"
-    "@types/react" "*"
-
-"@types/react-router-5@npm:@types/react-router@5.1.14":
+"@types/react-router-4@npm:@types/react-router@5.1.14", "@types/react-router-5@npm:@types/react-router@5.1.14":
   version "5.1.14"
   resolved "https://registry.yarnpkg.com/@types/react-router/-/react-router-5.1.14.tgz#e0442f4eb4c446541ad7435d44a97f8fe6df40da"
   integrity sha512-LAJpqYUaCTMT2anZheoidiIymt8MuX286zoVFPM3DVb23aQBH0mAkFvzpd4LKqiolV8bBtZWT5Qp7hClCNDENw==
@@ -15619,9 +15602,9 @@ expect@^27.5.1:
     jest-message-util "^27.5.1"
 
 exponential-backoff@^3.1.1:
-  version "3.1.1"
-  resolved "https://registry.yarnpkg.com/exponential-backoff/-/exponential-backoff-3.1.1.tgz#64ac7526fe341ab18a39016cd22c787d01e00bf6"
-  integrity sha512-dX7e/LHVJ6W3DE1MHWi9S1EYzDESENfLrYohG2G++ovZrYOkm4Knwa0mc1cn84xJOR4KEU0WSchhLbd0UklbHw==
+  version "3.1.2"
+  resolved "https://registry.yarnpkg.com/exponential-backoff/-/exponential-backoff-3.1.2.tgz#a8f26adb96bf78e8cd8ad1037928d5e5c0679d91"
+  integrity sha512-8QxYTVXUkuy7fIIoitQkPwGonB8F3Zj8eEO8Sqg9Zv/bkI7RJAzowee4gr81Hak/dUTpA2Z7VfQgoijjPNlUZA==
 
 express@^4.10.7, express@^4.16.4, express@^4.17.1, express@^4.17.3, express@^4.18.1:
   version "4.18.2"
@@ -26944,7 +26927,8 @@ react-refresh@0.8.3:
   dependencies:
     "@remix-run/router" "1.0.2"
 
-"react-router-6@npm:react-router@6.3.0":
+"react-router-6@npm:react-router@6.3.0", react-router@6.3.0:
+  name react-router-6
   version "6.3.0"
   resolved "https://registry.yarnpkg.com/react-router/-/react-router-6.3.0.tgz#3970cc64b4cb4eae0c1ea5203a80334fdd175557"
   integrity sha512-7Wh1DzVQ+tlFjkeo+ujvjSqSJmkt1+8JO+T5xklPlgrh70y7ogx75ODRW0ThWhY7S+6yEDks8TYrtQe/aoboBQ==
@@ -26959,13 +26943,6 @@ react-router-dom@^6.2.2:
     history "^5.2.0"
     react-router "6.3.0"
 
-react-router@6.3.0:
-  version "6.3.0"
-  resolved "https://registry.yarnpkg.com/react-router/-/react-router-6.3.0.tgz#3970cc64b4cb4eae0c1ea5203a80334fdd175557"
-  integrity sha512-7Wh1DzVQ+tlFjkeo+ujvjSqSJmkt1+8JO+T5xklPlgrh70y7ogx75ODRW0ThWhY7S+6yEDks8TYrtQe/aoboBQ==
-  dependencies:
-    history "^5.2.0"
-
 react@^18.0.0:
   version "18.0.0"
   resolved "https://registry.yarnpkg.com/react/-/react-18.0.0.tgz#b468736d1f4a5891f38585ba8e8fb29f91c3cb96"
@@ -29666,7 +29643,7 @@ string-template@~0.2.1:
   resolved "https://registry.yarnpkg.com/string-template/-/string-template-0.2.1.tgz#42932e598a352d01fc22ec3367d9d84eec6c9add"
   integrity sha1-QpMuWYo1LQH8IuwzZ9nYTuxsmt0=
 
-"string-width-cjs@npm:string-width@^4.2.0":
+"string-width-cjs@npm:string-width@^4.2.0", "string-width@^1.0.2 || 2 || 3 || 4", string-width@^4.0.0, string-width@^4.1.0, string-width@^4.2.0, string-width@^4.2.2, string-width@^4.2.3:
   version "4.2.3"
   resolved "https://registry.yarnpkg.com/string-width/-/string-width-4.2.3.tgz#269c7117d27b05ad2e536830a8ec895ef9c6d010"
   integrity sha512-wKyQRQpjJ0sIp62ErSZdGsjMJWsap5oRNihHhu6G7JVO/9jIB6UyevL+tXuOqrng8j/cxKTWyWUwvSTriiZz/g==
@@ -29683,15 +29660,6 @@ string-template@~0.2.1:
     is-fullwidth-code-point "^2.0.0"
     strip-ansi "^4.0.0"
 
-"string-width@^1.0.2 || 2 || 3 || 4", string-width@^4.0.0, string-width@^4.1.0, string-width@^4.2.0, string-width@^4.2.2, string-width@^4.2.3:
-  version "4.2.3"
-  resolved "https://registry.yarnpkg.com/string-width/-/string-width-4.2.3.tgz#269c7117d27b05ad2e536830a8ec895ef9c6d010"
-  integrity sha512-wKyQRQpjJ0sIp62ErSZdGsjMJWsap5oRNihHhu6G7JVO/9jIB6UyevL+tXuOqrng8j/cxKTWyWUwvSTriiZz/g==
-  dependencies:
-    emoji-regex "^8.0.0"
-    is-fullwidth-code-point "^3.0.0"
-    strip-ansi "^6.0.1"
-
 string-width@^3.0.0, string-width@^3.1.0:
   version "3.1.0"
   resolved "https://registry.yarnpkg.com/string-width/-/string-width-3.1.0.tgz#22767be21b62af1081574306f69ac51b62203961"
@@ -29796,7 +29764,7 @@ stringify-object@^3.2.1:
     is-obj "^1.0.1"
     is-regexp "^1.0.0"
 
-"strip-ansi-cjs@npm:strip-ansi@^6.0.1":
+"strip-ansi-cjs@npm:strip-ansi@^6.0.1", strip-ansi@^6.0.0, strip-ansi@^6.0.1:
   version "6.0.1"
   resolved "https://registry.yarnpkg.com/strip-ansi/-/strip-ansi-6.0.1.tgz#9e26c63d30f53443e9489495b2105d37b67a85d9"
   integrity sha512-Y38VPSHcqkFrCpFnQ9vuSXmquuv5oXOKpGeT6aGrr3o3Gc9AlVa6JBfUSOCnbxGGZF+/0ooI7KrPuUSztUdU5A==
@@ -29831,13 +29799,6 @@ strip-ansi@^5.0.0, strip-ansi@^5.1.0, strip-ansi@^5.2.0:
   dependencies:
     ansi-regex "^4.1.0"
 
-strip-ansi@^6.0.0, strip-ansi@^6.0.1:
-  version "6.0.1"
-  resolved "https://registry.yarnpkg.com/strip-ansi/-/strip-ansi-6.0.1.tgz#9e26c63d30f53443e9489495b2105d37b67a85d9"
-  integrity sha512-Y38VPSHcqkFrCpFnQ9vuSXmquuv5oXOKpGeT6aGrr3o3Gc9AlVa6JBfUSOCnbxGGZF+/0ooI7KrPuUSztUdU5A==
-  dependencies:
-    ansi-regex "^5.0.1"
-
 strip-ansi@^7.0.1:
   version "7.0.1"
   resolved "https://registry.yarnpkg.com/strip-ansi/-/strip-ansi-7.0.1.tgz#61740a08ce36b61e50e65653f07060d000975fb2"
@@ -32842,7 +32803,7 @@ workerpool@^6.4.0:
   resolved "https://registry.yarnpkg.com/workerpool/-/workerpool-6.4.0.tgz#f8d5cfb45fde32fa3b7af72ad617c3369567a462"
   integrity sha512-i3KR1mQMNwY2wx20ozq2EjISGtQWDIfV56We+yGJ5yDs8jTwQiLLaqHlkBHITlCuJnYlVRmXegxFxZg7gqI++A==
 
-"wrap-ansi-cjs@npm:wrap-ansi@^7.0.0":
+"wrap-ansi-cjs@npm:wrap-ansi@^7.0.0", wrap-ansi@^7.0.0:
   version "7.0.0"
   resolved "https://registry.yarnpkg.com/wrap-ansi/-/wrap-ansi-7.0.0.tgz#67e145cff510a6a6984bdf1152911d69d2eb9e43"
   integrity sha512-YVGIj2kamLSTxw6NsZjoBxfSwsn0ycdesmc4p+Q21c5zPuZ1pl+NfxVdxPtdHvmNVOQ6XSYG4AUtyt/Fi7D16Q==
@@ -32869,15 +32830,6 @@ wrap-ansi@^6.2.0:
     string-width "^4.1.0"
     strip-ansi "^6.0.0"
 
-wrap-ansi@^7.0.0:
-  version "7.0.0"
-  resolved "https://registry.yarnpkg.com/wrap-ansi/-/wrap-ansi-7.0.0.tgz#67e145cff510a6a6984bdf1152911d69d2eb9e43"
-  integrity sha512-YVGIj2kamLSTxw6NsZjoBxfSwsn0ycdesmc4p+Q21c5zPuZ1pl+NfxVdxPtdHvmNVOQ6XSYG4AUtyt/Fi7D16Q==
-  dependencies:
-    ansi-styles "^4.0.0"
-    string-width "^4.1.0"
-    strip-ansi "^6.0.0"
-
 wrap-ansi@^8.1.0:
   version "8.1.0"
   resolved "https://registry.yarnpkg.com/wrap-ansi/-/wrap-ansi-8.1.0.tgz#56dc22368ee570face1b49819975d9b9a5ead214"