diff --git a/src/bindings/python/setup.py b/src/bindings/python/setup.py
index 63bd5cb5..c093d37f 100644
--- a/src/bindings/python/setup.py
+++ b/src/bindings/python/setup.py
@@ -310,8 +310,6 @@ def build_cmake(self, extension):
         
         if DEP_DIR:
           cmake_args.append('-DLIBSEDML_DEPENDENCY_DIR=' + DEP_DIR)
-          cmake_args.append('-DEXTRA_LIBS=' + get_lib_full_path(os.path.join(DEP_DIR, 'lib'), 'expat'))
-          cmake_args.append('-DLIBEXPAT_INCLUDE_DIR=' + join(DEP_DIR, 'include'))
           cmake_args.append('-DLIBZ_INCLUDE_DIR=' + os.path.join(DEP_DIR, 'include'))
           zlib = get_lib_full_path(os.path.join(DEP_DIR, 'lib'), 'zlib')
           if not zlib: