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Whilst trying to run GAMBIT on other (non default) LD reference panels for other populations I noticed that the software kept defaulting to "G1K_EUR_3V5/chr$.vcf.gz". This was because I was trying to pass in the --ldref parameter rather than --ldfile. This incorrect usage is also referenced here: https://xqwen.github.io/ptwas/ - the "Quick Start" use case I was following.
The Issue
Whilst trying to run
GAMBIT
on other (non default) LD reference panels for other populations I noticed that the software kept defaulting to "G1K_EUR_3V5/chr$.vcf.gz". This was because I was trying to pass in the--ldref
parameter rather than--ldfile
. This incorrect usage is also referenced here: https://xqwen.github.io/ptwas/ - the "Quick Start" use case I was following.Lines of interest
GAMBIT/src/Main.cpp
Line 18 in 1644b80
https://github.com/corbinq/GAMBIT/blob/master/src/Main.cpp#L98
https://github.com/corbinq/GAMBIT/blob/master/src/Main.cpp#L191
TLDR;
Should be
--ldfile
rather than--ldref
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