diff --git a/capo-base.json b/capo-base.json
index 050accf..fe3b073 100644
--- a/capo-base.json
+++ b/capo-base.json
@@ -131,6 +131,16 @@
           "obj": "http://www.ebi.ac.uk/efo/EFO_0030005",
           "pred": "is_a",
           "sub": "http://www.ebi.ac.uk/efo/EFO_0010961"
+        },
+        {
+          "obj": "http://www.ebi.ac.uk/efo/EFO_0030080",
+          "pred": "is_a",
+          "sub": "http://www.ebi.ac.uk/efo/EFO_0030003"
+        },
+        {
+          "obj": "http://www.ebi.ac.uk/efo/EFO_0030080",
+          "pred": "is_a",
+          "sub": "http://www.ebi.ac.uk/efo/EFO_0030004"
         }
       ],
       "id": "http://purl.obolibrary.org/obo/capo/capo-base.json",
@@ -154,10 +164,10 @@
           },
           {
             "pred": "http://www.w3.org/2002/07/owl#versionInfo",
-            "val": "2024-09-25"
+            "val": "2025-06-04"
           }
         ],
-        "version": "http://purl.obolibrary.org/obo/capo/releases/2024-09-25/capo-base.json"
+        "version": "http://purl.obolibrary.org/obo/capo/releases/2025-06-04/capo-base.json"
       },
       "nodes": [
         {
@@ -642,6 +652,44 @@
           },
           "type": "CLASS"
         },
+        {
+          "id": "http://www.ebi.ac.uk/efo/EFO_0030003",
+          "lbl": "10x 3' transcription profiling",
+          "meta": {
+            "basicPropertyValues": [
+              {
+                "pred": "http://purl.org/dc/elements/1.1/creator",
+                "val": "paola"
+              }
+            ],
+            "definition": {
+              "val": "10x 3' transcription profiling is the 10x-based single-cell technology that sequences mRNA molecules from their 3' end.",
+              "xrefs": [
+                "https://orcid.org/0000-0002-8674-0039"
+              ]
+            }
+          },
+          "type": "CLASS"
+        },
+        {
+          "id": "http://www.ebi.ac.uk/efo/EFO_0030004",
+          "lbl": "10x 5' transcription profiling",
+          "meta": {
+            "basicPropertyValues": [
+              {
+                "pred": "http://purl.org/dc/elements/1.1/creator",
+                "val": "paola"
+              }
+            ],
+            "definition": {
+              "val": "10x 5' transcription profiling is the 10x-based single-cell technology that sequences mRNA molecules from their 5' end.",
+              "xrefs": [
+                "https://orcid.org/0000-0002-8674-0039"
+              ]
+            }
+          },
+          "type": "CLASS"
+        },
         {
           "id": "http://www.ebi.ac.uk/efo/EFO_0030019",
           "lbl": "Seq-Well S3",
@@ -1579,15 +1627,11 @@
           "type": "CLASS"
         },
         {
-          "id": "http://www.ebi.ac.uk/efo/EFO_0030003",
-          "type": "CLASS"
-        },
-        {
-          "id": "http://www.ebi.ac.uk/efo/EFO_0030004",
+          "id": "http://www.ebi.ac.uk/efo/EFO_0030005",
           "type": "CLASS"
         },
         {
-          "id": "http://www.ebi.ac.uk/efo/EFO_0030005",
+          "id": "http://www.ebi.ac.uk/efo/EFO_0030080",
           "type": "CLASS"
         }
       ]
diff --git a/capo-base.obo b/capo-base.obo
index 0848c33..df64f19 100644
--- a/capo-base.obo
+++ b/capo-base.obo
@@ -1,5 +1,5 @@
 format-version: 1.2
-data-version: capo/releases/2024-09-25/capo-base.owl
+data-version: capo/releases/2025-06-04/capo-base.owl
 idspace: dce http://purl.org/dc/elements/1.1/ 
 idspace: dcterms http://purl.org/dc/terms/ 
 idspace: oboInOwl http://www.geneontology.org/formats/oboInOwl# 
@@ -8,7 +8,7 @@ property_value: dce:type IAO:8000001
 property_value: dcterms:description "An ontology that contains CAP related ontology terms gathered from different ontologies " xsd:string
 property_value: dcterms:license https://creativecommons.org/licenses/by/4.0/
 property_value: dcterms:title "CAP Ontology" xsd:string
-property_value: owl:versionInfo "2024-09-25" xsd:string
+property_value: owl:versionInfo "2025-06-04" xsd:string
 
 [Term]
 id: CAPO:0000000
@@ -87,7 +87,7 @@ synonym: "10X v2 sequencing" RELATED []
 synonym: "10x v2 sequencing" RELATED []
 synonym: "10x_v2" RELATED []
 synonym: "10XV2" RELATED []
-is_a: EFO:0030003
+is_a: EFO:0030003 ! 10x 3' transcription profiling
 property_value: IAO:0000117 "Dani Welter" xsd:string
 
 [Term]
@@ -97,7 +97,7 @@ def: "10X 5' v2 is the second version of the 10x sequencing technology that sequ
 synonym: "10X 5' v2" EXACT []
 synonym: "10X 5' v2 sequencing" RELATED []
 synonym: "10x 5' v2 sequencing" RELATED []
-is_a: EFO:0030004
+is_a: EFO:0030004 ! 10x 5' transcription profiling
 property_value: IAO:0000117 "Dani Welter" xsd:string
 
 [Term]
@@ -111,7 +111,7 @@ synonym: "10X v1" RELATED []
 synonym: "10x v1" RELATED []
 synonym: "10x v1 sequencing" RELATED []
 synonym: "10XV1" RELATED []
-is_a: EFO:0030003
+is_a: EFO:0030003 ! 10x 3' transcription profiling
 property_value: IAO:0000117 "Dani Welter" xsd:string
 
 [Term]
@@ -125,7 +125,7 @@ synonym: "10x v3" RELATED []
 synonym: "10X v3 sequencing" RELATED []
 synonym: "10x v3 sequencing" RELATED []
 synonym: "10XV3" RELATED []
-is_a: EFO:0030003
+is_a: EFO:0030003 ! 10x 3' transcription profiling
 property_value: IAO:0000117 "Dani Welter" xsd:string
 
 [Term]
@@ -151,7 +151,21 @@ synonym: "10X 5' v3" RELATED []
 synonym: "10x 5' v3" RELATED []
 synonym: "10x 5' v3 sequencing" RELATED []
 synonym: "10x v1 5' sequencing" RELATED []
-is_a: EFO:0030004
+is_a: EFO:0030004 ! 10x 5' transcription profiling
+property_value: dce:creator "paola" xsd:string
+
+[Term]
+id: EFO:0030003
+name: 10x 3' transcription profiling
+def: "10x 3' transcription profiling is the 10x-based single-cell technology that sequences mRNA molecules from their 3' end." [https://orcid.org/0000-0002-8674-0039]
+is_a: EFO:0030080
+property_value: dce:creator "paola" xsd:string
+
+[Term]
+id: EFO:0030004
+name: 10x 5' transcription profiling
+def: "10x 5' transcription profiling is the 10x-based single-cell technology that sequences mRNA molecules from their 5' end." [https://orcid.org/0000-0002-8674-0039]
+is_a: EFO:0030080
 property_value: dce:creator "paola" xsd:string
 
 [Term]
diff --git a/capo-base.owl b/capo-base.owl
index eecad2b..2ee2daa 100644
--- a/capo-base.owl
+++ b/capo-base.owl
@@ -11,12 +11,12 @@
      xmlns:dcterms="http://purl.org/dc/terms/"
      xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#">
     <owl:Ontology rdf:about="http://purl.obolibrary.org/obo/capo/capo-base.owl">
-        <owl:versionIRI rdf:resource="http://purl.obolibrary.org/obo/capo/releases/2024-09-25/capo-base.owl"/>
+        <owl:versionIRI rdf:resource="http://purl.obolibrary.org/obo/capo/releases/2025-06-04/capo-base.owl"/>
         <dce:type rdf:resource="http://purl.obolibrary.org/obo/IAO_8000001"/>
         <dcterms:description>An ontology that contains CAP related ontology terms gathered from different ontologies </dcterms:description>
         <dcterms:license rdf:resource="https://creativecommons.org/licenses/by/4.0/"/>
         <dcterms:title>CAP Ontology</dcterms:title>
-        <owl:versionInfo>2024-09-25</owl:versionInfo>
+        <owl:versionInfo>2025-06-04</owl:versionInfo>
     </owl:Ontology>
     
 
@@ -1222,13 +1222,35 @@
 
     <!-- http://www.ebi.ac.uk/efo/EFO_0030003 -->
 
-    <owl:Class rdf:about="http://www.ebi.ac.uk/efo/EFO_0030003"/>
+    <owl:Class rdf:about="http://www.ebi.ac.uk/efo/EFO_0030003">
+        <rdfs:subClassOf rdf:resource="http://www.ebi.ac.uk/efo/EFO_0030080"/>
+        <obo:IAO_0000115>10x 3&apos; transcription profiling is the 10x-based single-cell technology that sequences mRNA molecules from their 3&apos; end.</obo:IAO_0000115>
+        <dce:creator>paola</dce:creator>
+        <rdfs:label>10x 3&apos; transcription profiling</rdfs:label>
+    </owl:Class>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://www.ebi.ac.uk/efo/EFO_0030003"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
+        <owl:annotatedTarget>10x 3&apos; transcription profiling is the 10x-based single-cell technology that sequences mRNA molecules from their 3&apos; end.</owl:annotatedTarget>
+        <oboInOwl:hasDbXref>https://orcid.org/0000-0002-8674-0039</oboInOwl:hasDbXref>
+    </owl:Axiom>
     
 
 
     <!-- http://www.ebi.ac.uk/efo/EFO_0030004 -->
 
-    <owl:Class rdf:about="http://www.ebi.ac.uk/efo/EFO_0030004"/>
+    <owl:Class rdf:about="http://www.ebi.ac.uk/efo/EFO_0030004">
+        <rdfs:subClassOf rdf:resource="http://www.ebi.ac.uk/efo/EFO_0030080"/>
+        <obo:IAO_0000115>10x 5&apos; transcription profiling is the 10x-based single-cell technology that sequences mRNA molecules from their 5&apos; end.</obo:IAO_0000115>
+        <dce:creator>paola</dce:creator>
+        <rdfs:label>10x 5&apos; transcription profiling</rdfs:label>
+    </owl:Class>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://www.ebi.ac.uk/efo/EFO_0030004"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
+        <owl:annotatedTarget>10x 5&apos; transcription profiling is the 10x-based single-cell technology that sequences mRNA molecules from their 5&apos; end.</owl:annotatedTarget>
+        <oboInOwl:hasDbXref>https://orcid.org/0000-0002-8674-0039</oboInOwl:hasDbXref>
+    </owl:Axiom>
     
 
 
@@ -1296,6 +1318,12 @@
         <oboInOwl:hasDbXref>http://orcid.org/0000-0002-1196-4871</oboInOwl:hasDbXref>
         <oboInOwl:hasDbXref>https://www.biorxiv.org/content/10.1101/434845v1</oboInOwl:hasDbXref>
     </owl:Axiom>
+    
+
+
+    <!-- http://www.ebi.ac.uk/efo/EFO_0030080 -->
+
+    <owl:Class rdf:about="http://www.ebi.ac.uk/efo/EFO_0030080"/>
 </rdf:RDF>
 
 
diff --git a/capo-full.json b/capo-full.json
index ef0130b..f385651 100644
--- a/capo-full.json
+++ b/capo-full.json
@@ -131,6 +131,16 @@
           "obj": "http://www.ebi.ac.uk/efo/EFO_0030005",
           "pred": "is_a",
           "sub": "http://www.ebi.ac.uk/efo/EFO_0010961"
+        },
+        {
+          "obj": "http://www.ebi.ac.uk/efo/EFO_0030080",
+          "pred": "is_a",
+          "sub": "http://www.ebi.ac.uk/efo/EFO_0030003"
+        },
+        {
+          "obj": "http://www.ebi.ac.uk/efo/EFO_0030080",
+          "pred": "is_a",
+          "sub": "http://www.ebi.ac.uk/efo/EFO_0030004"
         }
       ],
       "id": "http://purl.obolibrary.org/obo/capo/capo-full.json",
@@ -150,10 +160,10 @@
           },
           {
             "pred": "http://www.w3.org/2002/07/owl#versionInfo",
-            "val": "2024-09-25"
+            "val": "2025-06-04"
           }
         ],
-        "version": "http://purl.obolibrary.org/obo/capo/releases/2024-09-25/capo-full.json"
+        "version": "http://purl.obolibrary.org/obo/capo/releases/2025-06-04/capo-full.json"
       },
       "nodes": [
         {
@@ -638,6 +648,44 @@
           },
           "type": "CLASS"
         },
+        {
+          "id": "http://www.ebi.ac.uk/efo/EFO_0030003",
+          "lbl": "10x 3' transcription profiling",
+          "meta": {
+            "basicPropertyValues": [
+              {
+                "pred": "http://purl.org/dc/elements/1.1/creator",
+                "val": "paola"
+              }
+            ],
+            "definition": {
+              "val": "10x 3' transcription profiling is the 10x-based single-cell technology that sequences mRNA molecules from their 3' end.",
+              "xrefs": [
+                "https://orcid.org/0000-0002-8674-0039"
+              ]
+            }
+          },
+          "type": "CLASS"
+        },
+        {
+          "id": "http://www.ebi.ac.uk/efo/EFO_0030004",
+          "lbl": "10x 5' transcription profiling",
+          "meta": {
+            "basicPropertyValues": [
+              {
+                "pred": "http://purl.org/dc/elements/1.1/creator",
+                "val": "paola"
+              }
+            ],
+            "definition": {
+              "val": "10x 5' transcription profiling is the 10x-based single-cell technology that sequences mRNA molecules from their 5' end.",
+              "xrefs": [
+                "https://orcid.org/0000-0002-8674-0039"
+              ]
+            }
+          },
+          "type": "CLASS"
+        },
         {
           "id": "http://www.ebi.ac.uk/efo/EFO_0030019",
           "lbl": "Seq-Well S3",
@@ -1570,15 +1618,11 @@
           "type": "CLASS"
         },
         {
-          "id": "http://www.ebi.ac.uk/efo/EFO_0030003",
-          "type": "CLASS"
-        },
-        {
-          "id": "http://www.ebi.ac.uk/efo/EFO_0030004",
+          "id": "http://www.ebi.ac.uk/efo/EFO_0030005",
           "type": "CLASS"
         },
         {
-          "id": "http://www.ebi.ac.uk/efo/EFO_0030005",
+          "id": "http://www.ebi.ac.uk/efo/EFO_0030080",
           "type": "CLASS"
         }
       ]
diff --git a/capo-full.obo b/capo-full.obo
index 4186620..b151f7f 100644
--- a/capo-full.obo
+++ b/capo-full.obo
@@ -1,5 +1,5 @@
 format-version: 1.2
-data-version: capo/releases/2024-09-25/capo-full.owl
+data-version: capo/releases/2025-06-04/capo-full.owl
 idspace: dce http://purl.org/dc/elements/1.1/ 
 idspace: dcterms http://purl.org/dc/terms/ 
 idspace: oboInOwl http://www.geneontology.org/formats/oboInOwl# 
@@ -7,7 +7,7 @@ ontology: capo/capo-full
 property_value: dcterms:description "An ontology that contains CAP related ontology terms gathered from different ontologies " xsd:string
 property_value: dcterms:license https://creativecommons.org/licenses/by/4.0/
 property_value: dcterms:title "CAP Ontology" xsd:string
-property_value: owl:versionInfo "2024-09-25" xsd:string
+property_value: owl:versionInfo "2025-06-04" xsd:string
 
 [Term]
 id: CAPO:0000000
@@ -86,7 +86,7 @@ synonym: "10X v2 sequencing" RELATED []
 synonym: "10x v2 sequencing" RELATED []
 synonym: "10x_v2" RELATED []
 synonym: "10XV2" RELATED []
-is_a: EFO:0030003
+is_a: EFO:0030003 ! 10x 3' transcription profiling
 property_value: IAO:0000117 "Dani Welter" xsd:string
 
 [Term]
@@ -96,7 +96,7 @@ def: "10X 5' v2 is the second version of the 10x sequencing technology that sequ
 synonym: "10X 5' v2" EXACT []
 synonym: "10X 5' v2 sequencing" RELATED []
 synonym: "10x 5' v2 sequencing" RELATED []
-is_a: EFO:0030004
+is_a: EFO:0030004 ! 10x 5' transcription profiling
 property_value: IAO:0000117 "Dani Welter" xsd:string
 
 [Term]
@@ -110,7 +110,7 @@ synonym: "10X v1" RELATED []
 synonym: "10x v1" RELATED []
 synonym: "10x v1 sequencing" RELATED []
 synonym: "10XV1" RELATED []
-is_a: EFO:0030003
+is_a: EFO:0030003 ! 10x 3' transcription profiling
 property_value: IAO:0000117 "Dani Welter" xsd:string
 
 [Term]
@@ -124,7 +124,7 @@ synonym: "10x v3" RELATED []
 synonym: "10X v3 sequencing" RELATED []
 synonym: "10x v3 sequencing" RELATED []
 synonym: "10XV3" RELATED []
-is_a: EFO:0030003
+is_a: EFO:0030003 ! 10x 3' transcription profiling
 property_value: IAO:0000117 "Dani Welter" xsd:string
 
 [Term]
@@ -150,7 +150,21 @@ synonym: "10X 5' v3" RELATED []
 synonym: "10x 5' v3" RELATED []
 synonym: "10x 5' v3 sequencing" RELATED []
 synonym: "10x v1 5' sequencing" RELATED []
-is_a: EFO:0030004
+is_a: EFO:0030004 ! 10x 5' transcription profiling
+property_value: dce:creator "paola" xsd:string
+
+[Term]
+id: EFO:0030003
+name: 10x 3' transcription profiling
+def: "10x 3' transcription profiling is the 10x-based single-cell technology that sequences mRNA molecules from their 3' end." [https://orcid.org/0000-0002-8674-0039]
+is_a: EFO:0030080
+property_value: dce:creator "paola" xsd:string
+
+[Term]
+id: EFO:0030004
+name: 10x 5' transcription profiling
+def: "10x 5' transcription profiling is the 10x-based single-cell technology that sequences mRNA molecules from their 5' end." [https://orcid.org/0000-0002-8674-0039]
+is_a: EFO:0030080
 property_value: dce:creator "paola" xsd:string
 
 [Term]
diff --git a/capo-full.owl b/capo-full.owl
index a66a4b7..9fd58db 100644
--- a/capo-full.owl
+++ b/capo-full.owl
@@ -11,11 +11,11 @@
      xmlns:dcterms="http://purl.org/dc/terms/"
      xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#">
     <owl:Ontology rdf:about="http://purl.obolibrary.org/obo/capo/capo-full.owl">
-        <owl:versionIRI rdf:resource="http://purl.obolibrary.org/obo/capo/releases/2024-09-25/capo-full.owl"/>
+        <owl:versionIRI rdf:resource="http://purl.obolibrary.org/obo/capo/releases/2025-06-04/capo-full.owl"/>
         <dcterms:description>An ontology that contains CAP related ontology terms gathered from different ontologies </dcterms:description>
         <dcterms:license rdf:resource="https://creativecommons.org/licenses/by/4.0/"/>
         <dcterms:title>CAP Ontology</dcterms:title>
-        <owl:versionInfo>2024-09-25</owl:versionInfo>
+        <owl:versionInfo>2025-06-04</owl:versionInfo>
     </owl:Ontology>
     
 
@@ -1215,13 +1215,35 @@
 
     <!-- http://www.ebi.ac.uk/efo/EFO_0030003 -->
 
-    <owl:Class rdf:about="http://www.ebi.ac.uk/efo/EFO_0030003"/>
+    <owl:Class rdf:about="http://www.ebi.ac.uk/efo/EFO_0030003">
+        <rdfs:subClassOf rdf:resource="http://www.ebi.ac.uk/efo/EFO_0030080"/>
+        <obo:IAO_0000115>10x 3&apos; transcription profiling is the 10x-based single-cell technology that sequences mRNA molecules from their 3&apos; end.</obo:IAO_0000115>
+        <dce:creator>paola</dce:creator>
+        <rdfs:label>10x 3&apos; transcription profiling</rdfs:label>
+    </owl:Class>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://www.ebi.ac.uk/efo/EFO_0030003"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
+        <owl:annotatedTarget>10x 3&apos; transcription profiling is the 10x-based single-cell technology that sequences mRNA molecules from their 3&apos; end.</owl:annotatedTarget>
+        <oboInOwl:hasDbXref>https://orcid.org/0000-0002-8674-0039</oboInOwl:hasDbXref>
+    </owl:Axiom>
     
 
 
     <!-- http://www.ebi.ac.uk/efo/EFO_0030004 -->
 
-    <owl:Class rdf:about="http://www.ebi.ac.uk/efo/EFO_0030004"/>
+    <owl:Class rdf:about="http://www.ebi.ac.uk/efo/EFO_0030004">
+        <rdfs:subClassOf rdf:resource="http://www.ebi.ac.uk/efo/EFO_0030080"/>
+        <obo:IAO_0000115>10x 5&apos; transcription profiling is the 10x-based single-cell technology that sequences mRNA molecules from their 5&apos; end.</obo:IAO_0000115>
+        <dce:creator>paola</dce:creator>
+        <rdfs:label>10x 5&apos; transcription profiling</rdfs:label>
+    </owl:Class>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://www.ebi.ac.uk/efo/EFO_0030004"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
+        <owl:annotatedTarget>10x 5&apos; transcription profiling is the 10x-based single-cell technology that sequences mRNA molecules from their 5&apos; end.</owl:annotatedTarget>
+        <oboInOwl:hasDbXref>https://orcid.org/0000-0002-8674-0039</oboInOwl:hasDbXref>
+    </owl:Axiom>
     
 
 
@@ -1289,6 +1311,12 @@
         <oboInOwl:hasDbXref>http://orcid.org/0000-0002-1196-4871</oboInOwl:hasDbXref>
         <oboInOwl:hasDbXref>https://www.biorxiv.org/content/10.1101/434845v1</oboInOwl:hasDbXref>
     </owl:Axiom>
+    
+
+
+    <!-- http://www.ebi.ac.uk/efo/EFO_0030080 -->
+
+    <owl:Class rdf:about="http://www.ebi.ac.uk/efo/EFO_0030080"/>
 </rdf:RDF>
 
 
diff --git a/capo-simple.json b/capo-simple.json
index 0ca3d7f..07b2364 100644
--- a/capo-simple.json
+++ b/capo-simple.json
@@ -18,10 +18,10 @@
           },
           {
             "pred": "http://www.w3.org/2002/07/owl#versionInfo",
-            "val": "2024-09-25"
+            "val": "2025-06-04"
           }
         ],
-        "version": "http://purl.obolibrary.org/obo/capo/releases/2024-09-25/capo-simple.json"
+        "version": "http://purl.obolibrary.org/obo/capo/releases/2025-06-04/capo-simple.json"
       },
       "nodes": [
         {
diff --git a/capo-simple.obo b/capo-simple.obo
index 47525c2..357e70d 100644
--- a/capo-simple.obo
+++ b/capo-simple.obo
@@ -1,10 +1,10 @@
 format-version: 1.2
-data-version: capo/releases/2024-09-25/capo-simple.owl
+data-version: capo/releases/2025-06-04/capo-simple.owl
 idspace: dc http://purl.org/dc/elements/1.1/ 
 idspace: oboInOwl http://www.geneontology.org/formats/oboInOwl# 
 idspace: terms http://purl.org/dc/terms/ 
 ontology: capo/capo-simple
-property_value: owl:versionInfo "2024-09-25" xsd:string
+property_value: owl:versionInfo "2025-06-04" xsd:string
 property_value: terms:description "An ontology that contains CAP related ontology terms gathered from different ontologies " xsd:string
 property_value: terms:license https://creativecommons.org/licenses/by/4.0/
 property_value: terms:title "CAP Ontology" xsd:string
diff --git a/capo-simple.owl b/capo-simple.owl
index 0d695e2..68c391e 100644
--- a/capo-simple.owl
+++ b/capo-simple.owl
@@ -11,11 +11,11 @@
      xmlns:terms="http://purl.org/dc/terms/"
      xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#">
     <owl:Ontology rdf:about="http://purl.obolibrary.org/obo/capo/capo-simple.owl">
-        <owl:versionIRI rdf:resource="http://purl.obolibrary.org/obo/capo/releases/2024-09-25/capo-simple.owl"/>
+        <owl:versionIRI rdf:resource="http://purl.obolibrary.org/obo/capo/releases/2025-06-04/capo-simple.owl"/>
         <terms:description>An ontology that contains CAP related ontology terms gathered from different ontologies </terms:description>
         <terms:license rdf:resource="https://creativecommons.org/licenses/by/4.0/"/>
         <terms:title>CAP Ontology</terms:title>
-        <owl:versionInfo>2024-09-25</owl:versionInfo>
+        <owl:versionInfo>2025-06-04</owl:versionInfo>
     </owl:Ontology>
     
 
diff --git a/capo.json b/capo.json
index da930b9..dfa6f0a 100644
--- a/capo.json
+++ b/capo.json
@@ -131,6 +131,16 @@
           "obj": "http://www.ebi.ac.uk/efo/EFO_0030005",
           "pred": "is_a",
           "sub": "http://www.ebi.ac.uk/efo/EFO_0010961"
+        },
+        {
+          "obj": "http://www.ebi.ac.uk/efo/EFO_0030080",
+          "pred": "is_a",
+          "sub": "http://www.ebi.ac.uk/efo/EFO_0030003"
+        },
+        {
+          "obj": "http://www.ebi.ac.uk/efo/EFO_0030080",
+          "pred": "is_a",
+          "sub": "http://www.ebi.ac.uk/efo/EFO_0030004"
         }
       ],
       "id": "http://purl.obolibrary.org/obo/capo.json",
@@ -150,10 +160,10 @@
           },
           {
             "pred": "http://www.w3.org/2002/07/owl#versionInfo",
-            "val": "2024-09-25"
+            "val": "2025-06-04"
           }
         ],
-        "version": "http://purl.obolibrary.org/obo/capo/releases/2024-09-25/capo.json"
+        "version": "http://purl.obolibrary.org/obo/capo/releases/2025-06-04/capo.json"
       },
       "nodes": [
         {
@@ -638,6 +648,44 @@
           },
           "type": "CLASS"
         },
+        {
+          "id": "http://www.ebi.ac.uk/efo/EFO_0030003",
+          "lbl": "10x 3' transcription profiling",
+          "meta": {
+            "basicPropertyValues": [
+              {
+                "pred": "http://purl.org/dc/elements/1.1/creator",
+                "val": "paola"
+              }
+            ],
+            "definition": {
+              "val": "10x 3' transcription profiling is the 10x-based single-cell technology that sequences mRNA molecules from their 3' end.",
+              "xrefs": [
+                "https://orcid.org/0000-0002-8674-0039"
+              ]
+            }
+          },
+          "type": "CLASS"
+        },
+        {
+          "id": "http://www.ebi.ac.uk/efo/EFO_0030004",
+          "lbl": "10x 5' transcription profiling",
+          "meta": {
+            "basicPropertyValues": [
+              {
+                "pred": "http://purl.org/dc/elements/1.1/creator",
+                "val": "paola"
+              }
+            ],
+            "definition": {
+              "val": "10x 5' transcription profiling is the 10x-based single-cell technology that sequences mRNA molecules from their 5' end.",
+              "xrefs": [
+                "https://orcid.org/0000-0002-8674-0039"
+              ]
+            }
+          },
+          "type": "CLASS"
+        },
         {
           "id": "http://www.ebi.ac.uk/efo/EFO_0030019",
           "lbl": "Seq-Well S3",
@@ -1570,15 +1618,11 @@
           "type": "CLASS"
         },
         {
-          "id": "http://www.ebi.ac.uk/efo/EFO_0030003",
-          "type": "CLASS"
-        },
-        {
-          "id": "http://www.ebi.ac.uk/efo/EFO_0030004",
+          "id": "http://www.ebi.ac.uk/efo/EFO_0030005",
           "type": "CLASS"
         },
         {
-          "id": "http://www.ebi.ac.uk/efo/EFO_0030005",
+          "id": "http://www.ebi.ac.uk/efo/EFO_0030080",
           "type": "CLASS"
         }
       ]
diff --git a/capo.obo b/capo.obo
index da668ec..42c85ff 100644
--- a/capo.obo
+++ b/capo.obo
@@ -1,5 +1,5 @@
 format-version: 1.2
-data-version: releases/2024-09-25
+data-version: releases/2025-06-04
 idspace: dce http://purl.org/dc/elements/1.1/ 
 idspace: dcterms http://purl.org/dc/terms/ 
 idspace: oboInOwl http://www.geneontology.org/formats/oboInOwl# 
@@ -7,7 +7,7 @@ ontology: capo
 property_value: dcterms:description "An ontology that contains CAP related ontology terms gathered from different ontologies " xsd:string
 property_value: dcterms:license https://creativecommons.org/licenses/by/4.0/
 property_value: dcterms:title "CAP Ontology" xsd:string
-property_value: owl:versionInfo "2024-09-25" xsd:string
+property_value: owl:versionInfo "2025-06-04" xsd:string
 
 [Term]
 id: CAPO:0000000
@@ -86,7 +86,7 @@ synonym: "10X v2 sequencing" RELATED []
 synonym: "10x v2 sequencing" RELATED []
 synonym: "10x_v2" RELATED []
 synonym: "10XV2" RELATED []
-is_a: EFO:0030003
+is_a: EFO:0030003 ! 10x 3' transcription profiling
 property_value: IAO:0000117 "Dani Welter" xsd:string
 
 [Term]
@@ -96,7 +96,7 @@ def: "10X 5' v2 is the second version of the 10x sequencing technology that sequ
 synonym: "10X 5' v2" EXACT []
 synonym: "10X 5' v2 sequencing" RELATED []
 synonym: "10x 5' v2 sequencing" RELATED []
-is_a: EFO:0030004
+is_a: EFO:0030004 ! 10x 5' transcription profiling
 property_value: IAO:0000117 "Dani Welter" xsd:string
 
 [Term]
@@ -110,7 +110,7 @@ synonym: "10X v1" RELATED []
 synonym: "10x v1" RELATED []
 synonym: "10x v1 sequencing" RELATED []
 synonym: "10XV1" RELATED []
-is_a: EFO:0030003
+is_a: EFO:0030003 ! 10x 3' transcription profiling
 property_value: IAO:0000117 "Dani Welter" xsd:string
 
 [Term]
@@ -124,7 +124,7 @@ synonym: "10x v3" RELATED []
 synonym: "10X v3 sequencing" RELATED []
 synonym: "10x v3 sequencing" RELATED []
 synonym: "10XV3" RELATED []
-is_a: EFO:0030003
+is_a: EFO:0030003 ! 10x 3' transcription profiling
 property_value: IAO:0000117 "Dani Welter" xsd:string
 
 [Term]
@@ -150,7 +150,21 @@ synonym: "10X 5' v3" RELATED []
 synonym: "10x 5' v3" RELATED []
 synonym: "10x 5' v3 sequencing" RELATED []
 synonym: "10x v1 5' sequencing" RELATED []
-is_a: EFO:0030004
+is_a: EFO:0030004 ! 10x 5' transcription profiling
+property_value: dce:creator "paola" xsd:string
+
+[Term]
+id: EFO:0030003
+name: 10x 3' transcription profiling
+def: "10x 3' transcription profiling is the 10x-based single-cell technology that sequences mRNA molecules from their 3' end." [https://orcid.org/0000-0002-8674-0039]
+is_a: EFO:0030080
+property_value: dce:creator "paola" xsd:string
+
+[Term]
+id: EFO:0030004
+name: 10x 5' transcription profiling
+def: "10x 5' transcription profiling is the 10x-based single-cell technology that sequences mRNA molecules from their 5' end." [https://orcid.org/0000-0002-8674-0039]
+is_a: EFO:0030080
 property_value: dce:creator "paola" xsd:string
 
 [Term]
diff --git a/capo.owl b/capo.owl
index 168fca0..d74586b 100644
--- a/capo.owl
+++ b/capo.owl
@@ -11,11 +11,11 @@
      xmlns:dcterms="http://purl.org/dc/terms/"
      xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#">
     <owl:Ontology rdf:about="http://purl.obolibrary.org/obo/capo.owl">
-        <owl:versionIRI rdf:resource="http://purl.obolibrary.org/obo/capo/releases/2024-09-25/capo.owl"/>
+        <owl:versionIRI rdf:resource="http://purl.obolibrary.org/obo/capo/releases/2025-06-04/capo.owl"/>
         <dcterms:description>An ontology that contains CAP related ontology terms gathered from different ontologies </dcterms:description>
         <dcterms:license rdf:resource="https://creativecommons.org/licenses/by/4.0/"/>
         <dcterms:title>CAP Ontology</dcterms:title>
-        <owl:versionInfo>2024-09-25</owl:versionInfo>
+        <owl:versionInfo>2025-06-04</owl:versionInfo>
     </owl:Ontology>
     
 
@@ -1215,13 +1215,35 @@
 
     <!-- http://www.ebi.ac.uk/efo/EFO_0030003 -->
 
-    <owl:Class rdf:about="http://www.ebi.ac.uk/efo/EFO_0030003"/>
+    <owl:Class rdf:about="http://www.ebi.ac.uk/efo/EFO_0030003">
+        <rdfs:subClassOf rdf:resource="http://www.ebi.ac.uk/efo/EFO_0030080"/>
+        <obo:IAO_0000115>10x 3&apos; transcription profiling is the 10x-based single-cell technology that sequences mRNA molecules from their 3&apos; end.</obo:IAO_0000115>
+        <dce:creator>paola</dce:creator>
+        <rdfs:label>10x 3&apos; transcription profiling</rdfs:label>
+    </owl:Class>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://www.ebi.ac.uk/efo/EFO_0030003"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
+        <owl:annotatedTarget>10x 3&apos; transcription profiling is the 10x-based single-cell technology that sequences mRNA molecules from their 3&apos; end.</owl:annotatedTarget>
+        <oboInOwl:hasDbXref>https://orcid.org/0000-0002-8674-0039</oboInOwl:hasDbXref>
+    </owl:Axiom>
     
 
 
     <!-- http://www.ebi.ac.uk/efo/EFO_0030004 -->
 
-    <owl:Class rdf:about="http://www.ebi.ac.uk/efo/EFO_0030004"/>
+    <owl:Class rdf:about="http://www.ebi.ac.uk/efo/EFO_0030004">
+        <rdfs:subClassOf rdf:resource="http://www.ebi.ac.uk/efo/EFO_0030080"/>
+        <obo:IAO_0000115>10x 5&apos; transcription profiling is the 10x-based single-cell technology that sequences mRNA molecules from their 5&apos; end.</obo:IAO_0000115>
+        <dce:creator>paola</dce:creator>
+        <rdfs:label>10x 5&apos; transcription profiling</rdfs:label>
+    </owl:Class>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://www.ebi.ac.uk/efo/EFO_0030004"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
+        <owl:annotatedTarget>10x 5&apos; transcription profiling is the 10x-based single-cell technology that sequences mRNA molecules from their 5&apos; end.</owl:annotatedTarget>
+        <oboInOwl:hasDbXref>https://orcid.org/0000-0002-8674-0039</oboInOwl:hasDbXref>
+    </owl:Axiom>
     
 
 
@@ -1289,6 +1311,12 @@
         <oboInOwl:hasDbXref>http://orcid.org/0000-0002-1196-4871</oboInOwl:hasDbXref>
         <oboInOwl:hasDbXref>https://www.biorxiv.org/content/10.1101/434845v1</oboInOwl:hasDbXref>
     </owl:Axiom>
+    
+
+
+    <!-- http://www.ebi.ac.uk/efo/EFO_0030080 -->
+
+    <owl:Class rdf:about="http://www.ebi.ac.uk/efo/EFO_0030080"/>
 </rdf:RDF>
 
 
diff --git a/src/ontology/components/efo_cap.owl b/src/ontology/components/efo_cap.owl
index b0030a3..b0ea7ff 100644
--- a/src/ontology/components/efo_cap.owl
+++ b/src/ontology/components/efo_cap.owl
@@ -527,13 +527,35 @@
 
     <!-- http://www.ebi.ac.uk/efo/EFO_0030003 -->
 
-    <owl:Class rdf:about="http://www.ebi.ac.uk/efo/EFO_0030003"/>
-    
+    <owl:Class rdf:about="http://www.ebi.ac.uk/efo/EFO_0030003">
+        <rdfs:subClassOf rdf:resource="http://www.ebi.ac.uk/efo/EFO_0030080"/>
+        <obo:IAO_0000115>10x 3&apos; transcription profiling is the 10x-based single-cell technology that sequences mRNA molecules from their 3&apos; end.</obo:IAO_0000115>
+        <dc:creator>paola</dc:creator>
+        <rdfs:label>10x 3&apos; transcription profiling</rdfs:label>
+    </owl:Class>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://www.ebi.ac.uk/efo/EFO_0030003"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
+        <owl:annotatedTarget>10x 3&apos; transcription profiling is the 10x-based single-cell technology that sequences mRNA molecules from their 3&apos; end.</owl:annotatedTarget>
+        <oboInOwl:hasDbXref>https://orcid.org/0000-0002-8674-0039</oboInOwl:hasDbXref>
+    </owl:Axiom>
+
 
 
     <!-- http://www.ebi.ac.uk/efo/EFO_0030004 -->
 
-    <owl:Class rdf:about="http://www.ebi.ac.uk/efo/EFO_0030004"/>
+    <owl:Class rdf:about="http://www.ebi.ac.uk/efo/EFO_0030004">
+        <rdfs:subClassOf rdf:resource="http://www.ebi.ac.uk/efo/EFO_0030080"/>
+        <obo:IAO_0000115>10x 5&apos; transcription profiling is the 10x-based single-cell technology that sequences mRNA molecules from their 5&apos; end.</obo:IAO_0000115>
+        <dc:creator>paola</dc:creator>
+        <rdfs:label>10x 5&apos; transcription profiling</rdfs:label>
+    </owl:Class>
+    <owl:Axiom>
+        <owl:annotatedSource rdf:resource="http://www.ebi.ac.uk/efo/EFO_0030004"/>
+        <owl:annotatedProperty rdf:resource="http://purl.obolibrary.org/obo/IAO_0000115"/>
+        <owl:annotatedTarget>10x 5&apos; transcription profiling is the 10x-based single-cell technology that sequences mRNA molecules from their 5&apos; end.</owl:annotatedTarget>
+        <oboInOwl:hasDbXref>https://orcid.org/0000-0002-8674-0039</oboInOwl:hasDbXref>
+    </owl:Axiom>