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Blacklisted regions in applyFilter function without providing a bed file #128

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alexvasilikop opened this issue Jul 8, 2024 · 0 comments

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@alexvasilikop
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alexvasilikop commented Jul 8, 2024

Hello,

I was wondering which regions QDNAseq is using by default in applyFilters is used with the option blacklist = TRUE. We are using it like the following without providing any BED files for the blacklisted regions. Are there some regions blacklisted by default ? ( I noticed some are missing after applying the filters).

readCounts <- binReadCounts(bins, bamfiles = InputFile)
readCounts <- estimateCorrection(readCounts)
readCounts <- applyFilters(readCounts, residual = TRUE, blacklist = TRUE, chromosomes = NA)    # includes both X & Y
copyNumbers <- correctBins(readCounts)
copyNumbersNormalized <- normalizeBins(copyNumbers)
copyNumbersSmooth <- smoothOutlierBins(copyNumbersNormalized)

Thanks

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