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CellCenterModel

This is a program for a cell-centered model that represents the three-dimensional morphogenesis of a monolayer.

videos

In-plane deformation

with cell rearrangement without cell rearrangement

out-of-plane deformation

uniaxial cell division random cell division

apical constriction

circular pattern circumferential pattern

how to make and run

Parameter files (parameters.hpp) for the three patterns are included in each directory.

When executing, place one of them in the same hierarchy as the makefile. Then execute the following code.

make
./a.out

Any published work which utilizes this code shall include the following reference:

Tomohiro Mimura and Yasuhiro Inoue "Cell-center-based model for simulating three-dimensional monolayer tissue deformation", Journal of Theoretical Biology (2023)

@article{MIMURA2023111560,
    title = {Cell-center-based model for simulating three-dimensional monolayer tissue deformation},
    journal = {Journal of Theoretical Biology},
    volume = {571},
    pages = {111560},
    year = {2023},
    issn = {0022-5193},
    author = {Tomohiro Mimura and Yasuhiro Inoue}
}