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+,Attribute,Label,Description,Required,Cond_Req,Valid Values,Conditional Requirements,Component
+HTAN Parent Biospecimen ID,HTAN Parent Biospecimen ID,HTANParentBiospecimenID,HTAN Biospecimen Identifier (eg HTANx_yyy_zzz) indicating the biospecimen(s) from which these files were derived; multiple parent biospecimen should be comma-separated,True,,,,OtherAssay
+Assay Type,Assay Type,AssayType,"The type and level of assay this metadata applies to (e.g. RPPA, Nanostring DSP, etc.)",True,,,,OtherAssay
+HTAN Data File ID,HTAN Data File ID,HTANDataFileID,Self-identifier for this data file - HTAN ID of this file HTAN ID SOP (eg HTANx_yyy_zzz),True,,,,OtherAssay
+Component,Component,Component,"Category of metadata (e.g. Diagnosis, Biospecimen, scRNA-seq Level 1, etc.); provide the same one for all items/rows.",True,,,,OtherAssay
+Filename,Filename,filename,Name of a file ,True,,,,OtherAssay
+File Format,File Format,fileFormat,"Format of a file (e.g. txt, csv, fastq, bam, etc.)",True,,"['m', 'pdf', 'Sentrix descriptor file', 'czi', 'cell am', 'avi', 'mzML', 'sra', 'json', 'html', 'gzip', 'svg', 'gtf', 'DICOM', 'idat', 'am', 'bedgraph', 'cloupe', 'hdf5', 'gff3', 'wiggle', 'mtx', 'dat', 'bpm', 'fasta', 'flagstat', 'abf', 'plink', 'svs', 'md', 'bigwig', 'dup', 'fastq', 'chp', 'doc', 'sqlite', 'tar', 'sav', 'sam', 'bed gappedPeak', 'sdf', 'tif', 'powerpoint', 'cel', 'png', 'rmd', 'gct', 'fig', '7z', 'locs', 'mpg', 'pzfx', 'mov', 'bed', 'xml', 'msf', 'bai', 'maf', 'excel', 'tsv', 'bed narrowPeak', 'jpg', 'sif', 'raw', 'zip', 'ab1', 'mex', 'bam', 'RData', 'csv', 'tagAlign', 'Python script', 'hyperlink', 'bcf', 'tiff', 'recal', 'OME-TIFF', 'bed broadPeak', 'vcf', 'tranches', 'idx', 'seg', 'R script', 'bgzip', 'hic', 'txt']",,OtherAssay
+Processing Days from Index,Processing Days from Index,ProcessingDaysfromIndex,Number of days from the research participant's index date that the biospecimen was processed,True,,,,Biospecimen
+Histology Assessment Medium,Histology Assessment Medium,HistologyAssessmentMedium,The method of assessment used to characterize histology,False,,"['Microscopy', 'unknown', 'Digital', 'Other', '']",,Biospecimen
+Fixative Type,Fixative Type,FixativeType,Text term to identify the type of fixative used to preserve a tissue specimen,True,,"['None', 'Polaxamer', 'NP40 lysis buffer', 'Formalin', 'Carbodiimide', 'Dimidoester', 'TCL lysis buffer', 'Glutaraldehyde', '95% Ethanol', 'PAXgene tissue', ""Carnoy's Fixative"", 'Saline', 'Alcohol', 'Other', 'Cryo-store', 'OCT media', 'unknown', 'Methacarn', 'RNAlater', 'Dimethylacetamide', 'Para-benzoquinone', 'Acetone']",,Biospecimen
+Percent Normal Cells,Percent Normal Cells,PercentNormalCells,Numeric value to represent the percentage of normal cell content in a malignant tumor sample or specimen.,False,,,,Biospecimen
+Storage Method,Storage Method,StorageMethod,The method by which a biomaterial was stored after preservation or before another protocol was used.,True,,"['Frozen in liquid nitrogen', 'Not Applicable', 'RNAlater at 25C', 'unknown', 'Frozen at -150C', 'Refrigerated at 4 degrees', 'Frozen at -70C', 'Cut slide', 'Fresh', 'Desiccant at 4C', 'Frozen in vapor phase', 'Paraffin block', 'Frozen at -80C', '4C in vacuum chamber', 'Refrigerated vacuum chamber', 'RNAlater at -20C', 'Ambient temperature', 'RNAlater at 4C']",,Biospecimen
+Protocol Link,Protocol Link,ProtocolLink,"Protocols.io ID or DOI link to a free/open protocol resource describing in detail the assay protocol (e.g. surface markers used in Smart-seq, dissociation duration,  lot/batch numbers for key reagents such as primers, sequencing reagent kits, etc.) or the protocol by which the sample was obtained or generated.",True,,,,Biospecimen
+Histology Assessment By,Histology Assessment By,HistologyAssessmentBy,Text term describing who (in what role) made the histological assessments of the sample,False,,"['Pathologist', 'unknown', 'Other', 'Research Scientist', '']",,Biospecimen
+Number Proliferating Cells,Number Proliferating Cells,NumberProliferatingCells,Numeric value that represents the count of proliferating cells determined during pathologic review of the sample slide(s).,False,,,,Biospecimen
+Component,Component,Component,"Category of metadata (e.g. Diagnosis, Biospecimen, scRNA-seq Level 1, etc.); provide the same one for all items/rows.",True,,,,Biospecimen
+Collection Media,Collection Media,CollectionMedia,Material Specimen is collected into post procedure,False,,"['PBS', 'PBS+Serum', 'None', 'DMEM', 'RPMI+Serum', 'RPMI', 'DMEM+Serum', '']",,Biospecimen
+Percent Lymphocyte Infiltration,Percent Lymphocyte Infiltration,PercentLymphocyteInfiltration,Numeric value to represent the percentage of infiltration by lymphocytes in a solid tissue normal sample or specimen.,False,,,,Biospecimen
+Percent Granulocyte Infiltration,Percent Granulocyte Infiltration,PercentGranulocyteInfiltration,Numeric value to represent the percentage of infiltration by granulocytes in a tumor sample or specimen.,False,,,,Biospecimen
+Percent Neutrophil Infiltration,Percent Neutrophil Infiltration,PercentNeutrophilInfiltration,Numeric value to represent the percentage of infiltration by neutrophils in a tumor sample or specimen.,False,,,,Biospecimen
+Slicing Method,Slicing Method,SlicingMethod,Imaging specific: the method by which the tissue was sliced.,False,,"['Cryosectioning', 'Not Reported', 'unknown', 'Tissue molds', 'Vibratome', 'Sectioning', 'Sliding microtome', 'Other', '']",,Biospecimen
+Method of Nucleic Acid Isolation,Method of Nucleic Acid Isolation,MethodofNucleicAcidIsolation,"Bulk RNA & DNA-seq specific: method used for nucleic acid isolation. E.g. Qiagen Allprep, Qiagen miRNAeasy. [Text - max length 100]",False,,,,Biospecimen
+Timepoint Label,Timepoint Label,TimepointLabel,"Label to identify the time point at which the clinical data or biospecimen was obtained (e.g. Baseline, End of Treatment, Overall survival, Final). NO PHI/PII INFORMATION IS ALLOWED.",True,,,,Biospecimen
+Percent Necrosis,Percent Necrosis,PercentNecrosis,Numeric value to represent the percentage of cell death in a malignant tumor sample or specimen.,False,,,,Biospecimen
+Adjacent Biospecimen IDs,Adjacent Biospecimen IDs,AdjacentBiospecimenIDs,"List of HTAN Identifiers (separated by commas) of adjacent biospecimens cut from the same sample; for example HTA3_3000_3, HTA3_3000_4, ...",False,,,,Biospecimen
+Fiducial Marker,Fiducial Marker,FiducialMarker,Imaging specific: fiducial markers for the alignment of images taken across multiple rounds of imaging.,False,,"['Not Reported', 'unknown', 'Fluorescent Beads', 'Nuclear Stain - DAPI', 'Adhesive Markers', 'Grid Slides - Hemocytometer', 'Other', '']",,Biospecimen
+Mounting Medium,Mounting Medium,MountingMedium,"The solution in which the specimen is embedded, generally under a cover glass. It may be liquid, gum or resinous, soluble in water, alcohol or other solvents and be sealed from the external atmosphere by non-soluble ringing media",False,,"['PBS', 'Aqueous water based', 'Non-Aqueous Solvent based', 'Not Reported', 'Antifade without DAPI', 'unknown', 'Toluene', 'Antifade with DAPI', 'Xylene', '']",,Biospecimen
+Percent Stromal Cells,Percent Stromal Cells,PercentStromalCells,"Numeric value to represent the percentage of reactive cells that are present in a malignant tumor sample or specimen but are not malignant such as fibroblasts, vascular structures, etc.",False,,,,Biospecimen
+Percent Monocyte Infiltration,Percent Monocyte Infiltration,PercentMonocyteInfiltration,Numeric value to represent the percentage of monocyte infiltration in a sample or specimen.,False,,,,Biospecimen
+Collection Days from Index,Collection Days from Index,CollectionDaysfromIndex,Number of days from the research participant's index date that the biospecimen was obtained.,True,,,,Biospecimen
+Site Data Source,Site Data Source,SiteDataSource,"Text to identify the data source for the specimen/sample from within the HTAN center, if applicable. Any identifier used within the center to identify data sources. No PHI/PII is allowed.",False,,,,Biospecimen
+Percent Inflam Infiltration,Percent Inflam Infiltration,PercentInflamInfiltration,"Numeric value to represent local response to cellular injury, marked by capillary dilatation, edema and leukocyte infiltration; clinically, inflammation is manifest by redness, heat, pain, swelling and loss of function, with the need to heal damaged tissue.",False,,,,Biospecimen
+Degree of Dysplasia,Degree of Dysplasia,DegreeofDysplasia,Information related to the presence of cells that look abnormal under a microscope but are not cancer. Records the degree of dysplasia for the cyst or lesion under consideration.,False,,"['Carcinoma in Situ', 'unknown', 'Normal or basal cell hyperplasia or metaplasia', 'Mild dysplasia', 'Severe dysplasia', 'Moderate dysplasia', '']",,Biospecimen
+Acquisition Method Type,Acquisition Method Type,AcquisitionMethodType,Records the method of acquisition or source for the specimen under consideration.,True,,"['Re-excision', 'Shave Biopsy', 'Fine Needle Aspirate', 'Not specified', 'Punch Biopsy', 'BAL (bronchial alveolar lavage)', 'Endoscopic biopsy', 'Sentinel Node Biopsy', 'Lymphadenectomy - Regional Nodes', 'Induced sputum', 'Surgical Resection', 'Forceps biopsy', 'Other Acquisition Method', 'Excision', 'Cytobrush', 'Autopsy', 'Fluid collection', 'Blood draw', 'Non induced sputum', 'Core needle biopsy', 'Biopsy']",,Biospecimen
+Percent Eosinophil Infiltration,Percent Eosinophil Infiltration,PercentEosinophilInfiltration,Numeric value to represent the percentage of infiltration by eosinophils in a tumor sample or specimen.,False,,,,Biospecimen
+Percent Tumor Nuclei,Percent Tumor Nuclei,PercentTumorNuclei,Numeric value to represent the percentage of tumor nuclei in a malignant neoplasm sample or specimen.,False,,,,Biospecimen
+HTAN Parent ID,HTAN Parent ID,HTANParentID,HTAN ID of parent from which the biospecimen was obtained. Parent could be another biospecimen or a research participant.,True,,,,Biospecimen
+Dysplasia Fraction,Dysplasia Fraction,DysplasiaFraction,Resulting value to represent the number of pieces of dysplasia divided by the total number of pieces. [Text: max length 5],False,,,,Biospecimen
+Percent Tumor Cells,Percent Tumor Cells,PercentTumorCells,Numeric value that represents the percentage of infiltration by tumor cells in a sample.,False,,,,Biospecimen
+Preinvasive Morphology,Preinvasive Morphology,PreinvasiveMorphology,"Histologic Morphology not included in ICD-O-3 morphology codes, for preinvasive lesions included in the HTAN",False,,"['Melanoma in situ - acral-lentiginous', 'Atypical adenomatous hyperplasia', 'Squamous metaplasia - mature', 'Atypical melanocytic proliferation', 'Normal WDA', 'Carcinoma NOS', 'Moderate dysplasia', 'Benign tumor NOS', 'Squamous metaplasia - immature', 'Invasive melanoma - desmoplastic', 'Squamous Carcinoma in situ', 'Reserve cell hyperplasia', 'Mild dysplasia', 'Melanoma in situ - lentigo maligna type', 'No diagnosis possible', 'Invasive melanoma - acral lentiginous', 'Adenocarcinoma in situ - mucinous', 'Persistent melanoma in situ', 'Invasive melanoma - nevoid', 'Hamartoma', 'Invasive melanoma - nodular type', 'Invasive melanoma - superficial spreading', 'Adenocarcinoma in situ - non mucinous', 'Invasive melanoma - lentigo maligna', 'Scar - no residual melanoma', 'Melanoma in situ - superficial spreading', 'Melanocytic hyperplasia', 'Invasive melanoma - other', 'Melanoma in situ - arising in a giant congenital nevus', 'Severe dysplasia', 'Melanoma in situ - not otherwise classified', '']",,Biospecimen
+HTAN Biospecimen ID,HTAN Biospecimen ID,HTANBiospecimenID,HTAN ID associated with a biosample based on HTAN ID SOP (eg HTANx_yyy_zzz),True,,,,Biospecimen
+Processing Location,Processing Location,ProcessingLocation,"Site with an HTAN center where specimen processing occurs, if applicable. Any identifier used within the center to identify processing location. No PHI/PII is allowed.",False,,,,Biospecimen
+Tumor Infiltrating Lymphocytes,Tumor Infiltrating Lymphocytes,TumorInfiltratingLymphocytes,Measure of Tumor-Infiltrating Lymphocytes [Number],False,,,,Biospecimen
+Biospecimen Type,Biospecimen Type,BiospecimenType,Biospecimen Type,True,,"['Tissue Biospecimen Type', 'Analyte Biospecimen Type', 'Ascites Biospecimen Type', 'Stool Biospecimen Type', 'Mouth Rinse Biospecimen Type', 'Sputum Biospecimen Type', 'Cells Biospecimen Type', 'Urine Biospecimen Type', 'Bone Marrow Biospecimen Type', 'Fluids Biospecimen Type', 'Blood Biospecimen Type']",,Biospecimen
+Lysis Buffer,Lysis Buffer,LysisBuffer,scRNA-seq specific: Type of lysis buffer used,False,,,,Biospecimen
+Acquisition Method Other Specify,Acquisition Method Other Specify,AcquisitionMethodOtherSpecify,A custom acquisition method [Text - max length 100 characters],False,True,,"Acquisition Method Type -is- ""Other Acquisition Method""",Biospecimen
+Biospecimen Dimension 2,Biospecimen Dimension 2,BiospecimenDimension2,"Second dimension of tissue fragment (number, up to one decimal place) measured in units as defined by the ""dimensions_unit"" CDE",False,True,,"Biospecimen Type -is- ""Tissue Biospecimen Type"" || Biospecimen Type -is- ""Bone Marrow Biospecimen Type""",Biospecimen
+Total Volume,Total Volume,TotalVolume,Numeric value for the total amount of sample or specimen,False,True,,"Biospecimen Type -is- ""Tissue Biospecimen Type"" || Biospecimen Type -is- ""Urine Biospecimen Type"" || Biospecimen Type -is- ""Bone Marrow Biospecimen Type""",Biospecimen
+Biospecimen Dimension 1,Biospecimen Dimension 1,BiospecimenDimension1,"First dimension of tissue fragment (number, up to one decimal place) measured in units as defined by the ""dimensions_unit"" CDE",False,True,,"Biospecimen Type -is- ""Tissue Biospecimen Type"" || Biospecimen Type -is- ""Bone Marrow Biospecimen Type""",Biospecimen
+Biospecimen Dimension 3,Biospecimen Dimension 3,BiospecimenDimension3,"Third dimension of tissue fragment (number, up to one decimal place) measured in units as defined by the ""dimensions_unit"" CDE",False,True,,"Biospecimen Type -is- ""Tissue Biospecimen Type"" || Biospecimen Type -is- ""Bone Marrow Biospecimen Type""",Biospecimen
+Site of Resection or Biopsy,Site of Resection or Biopsy,SiteofResectionorBiopsy,"The text term used to describe the anatomic site of origin, of the patient's malignant disease, as described by the World Health Organization's (WHO) International Classification of Diseases for Oncology (ICD-O).",False,True,"['Glottis', 'Fundus of stomach', 'Trigone of bladder', 'Ciliary body', 'Acoustic nerve', 'Bone marrow', 'Pylorus', 'Ascending colon', 'Body of stomach', 'Skin of trunk', 'Retroperitoneum', 'Scrotum NOS', 'Meckel diverticulum', 'Lower lobe lung', 'Anal canal', 'Vallecula', 'Pancreatic duct', 'Lower-inner quadrant of breast', 'Overlapping lesion of small intestine', 'Connective subcutaneous and other soft tissues of head face and neck', 'Jejunum', 'Lesser curvature of stomach NOS', 'Tonsillar fossa', 'Pelvic bones sacrum coccyx and associated joints', 'Maxillary sinus', 'Parietal lobe', 'External upper lip', 'Optic nerve', 'Head of pancreas', 'Overlapping lesion of digestive system', 'Parametrium', 'Eye NOS', 'Not Reported', 'Connective subcutaneous and other soft tissues NOS', 'Overlapping lesion of lip oral cavity and pharynx', 'Brain NOS', 'Overlapping lesion of respiratory system and intrathoracic organs', 'Peripheral nerves and autonomic nervous system of head face and neck', 'Overlapping lesion of endocrine glands and related structures', 'Sublingual gland', 'Anterior surface of epiglottis', 'Mediastinum NOS', 'Thorax NOS', 'unknown primary site', 'Uvula', 'Ill-defined sites within respiratory system', 'Lung NOS', 'Mucosa of upper lip', 'Overlapping lesion of biliary tract', 'Body of pancreas', 'Frontal lobe', 'Adrenal gland NOS', 'Lacrimal gland', 'Cornea NOS', 'Aortic body and other paraganglia', 'Ureteric orifice', 'Nasal cavity', 'Axillary tail of breast', 'Overlapping lesion of breast', 'Upper-outer quadrant of breast', 'Gastric antrum', 'Bone of limb NOS', 'Posterior wall of bladder', 'External lower lip', 'Labium minus', 'Myometrium', 'Anterior wall of bladder', 'Overlapping lesion of lip', 'Ethmoid sinus', 'Stomach NOS', 'Abdominal esophagus', 'Intestinal tract NOS', 'Splenic flexure of colon', 'Female genital tract NOS', 'Ventral surface of tongue NOS', 'Hard palate', 'Border of tongue', 'Overlapping lesion of larynx', 'External ear', 'Reticuloendothelial system NOS', 'Spinal cord', 'Overlapping lesion of ill-defined sites', 'Connective subcutaneous and other soft tissues of pelvis', 'Long bones of upper limb scapula and associated joints', 'Descended testis', 'Temporal lobe', 'Lateral floor of mouth', 'Cerebellum NOS', 'Gallbladder', 'Labium majus', 'Overlapping lesion of penis', 'Overlapping lesion of cervix uteri', 'Transverse colon', 'Posterior wall of oropharynx', 'Cloacogenic zone', 'Clitoris', 'Vagina NOS', 'Vulva NOS', 'Supraglottis', 'Lower limb NOS', 'Mouth NOS', 'Overlapping lesion of major salivary glands', 'Bladder NOS', 'Upper third of esophagus', 'Overlapping lesion of bladder', 'Descending colon', 'Skin of lip NOS', 'Retromolar area', 'Lower third of esophagus', 'Lip NOS', 'Connective subcutaneous and other soft tissues of trunk NOS', 'Appendix', 'Overlapping lesion of heart mediastinum and pleura', 'Overlapping lesion of tonsil', 'Pelvic lymph nodes', 'Rectosigmoid junction', 'Overlapping lesion of corpus uteri', 'Biliary tract NOS', 'Liver', 'Overlapping lesion of retroperitoneum and peritoneum', 'Superior wall of nasopharynx', 'Testis NOS', 'Overlapping lesion of eye and adnexa', 'Mucosa of lower lip', 'Abdomen NOS', 'Heart', 'Peritoneum NOS', 'Pancreas NOS', 'Upper gum', 'Lower gum', 'Specified parts of peritoneum', 'Central portion of breast', 'Cheek mucosa', 'Urethra', 'Ventricle NOS', 'Glans penis', 'Conjunctiva', 'Nasopharynx NOS', 'Overlapping lesion of tongue', 'Carotid body', 'Round ligament', 'Paraspinal', 'Urinary system NOS', 'Vestibule of mouth', 'Isthmus uteri', 'Posterior wall of nasopharynx', 'Peripheral nerves and autonomic nervous system of upper limb and shoulder', 'Spermatic cord', 'Dome of bladder', 'Meninges NOS', 'Pyriform sinus', 'Ampulla of Vater', 'Upper respiratory tract NOS', 'Overlapping lesion of lung', 'Overlapping lesion of urinary organs', 'Overlapping lesion of stomach', 'Kidney NOS', 'Tongue NOS', 'Lymph node NOS', 'Hypopharynx NOS', 'Connective subcutaneous and other soft tissues of abdomen', 'Tail of pancreas', 'Choroid', 'Overlapping lesion of peripheral nerves and autonomic nervous system', 'Fallopian tube', 'Intra-abdominal lymph nodes', 'Head face or neck NOS', 'Pineal gland', 'Mandible', 'Corpus uteri', 'Upper limb NOS', 'Ovary', 'Overlapping lesion of skin', 'Uterus NOS', 'Commissure of lip', 'Broad ligament', 'Accessory sinus NOS', 'Exocervix', 'Intrahepatic bile duct', 'Greater curvature of stomach NOS', 'Waldeyer ring', 'Short bones of upper limb and associated joints', 'Overlapping lesion of bones joints and articular cartilage of limbs', 'Autonomic nervous system NOS', 'Middle third of esophagus', 'Anterior mediastinum', 'Other specified parts of pancreas', 'Thymus', 'Skin of scalp and neck', 'Parathyroid gland', 'Dorsal surface of tongue NOS', 'Hematopoietic system NOS', 'Overlapping lesion of brain and central nervous system', 'Subglottis', 'Connective subcutaneous and other soft tissues of lower limb and hip', 'Body of penis', 'Tonsil NOS', 'Spleen', 'Posterior wall of hypopharynx', 'Soft palate NOS', 'Fundus uteri', 'Mucosa of lip NOS', 'Overlapping lesion of nasopharynx', 'External lip NOS', 'Uterine adnexa', 'Laryngeal cartilage', 'Intrathoracic lymph nodes', 'Lower-outer quadrant of breast', 'Cervix uteri', 'Sphenoid sinus', 'Lingual tonsil', 'Olfactory nerve', 'Pharynx NOS', 'Anterior floor of mouth', 'Brain stem', 'Frontal sinus', 'Rectum NOS', 'Ileum', 'Main bronchus', 'Anus NOS', 'Hypopharyngeal aspect of aryepiglottic fold', 'unknown', 'Peripheral nerves and autonomic nervous system of lower limb and hip', 'Male genital organs NOS', 'Pituitary gland', 'Overlapping lesion of connective subcutaneous and other soft tissues', 'Parotid gland', 'Cortex of adrenal gland', 'Lymph nodes of multiple regions', 'Medulla of adrenal gland', 'Renal pelvis', 'Urachus', 'Lateral wall of bladder', 'Upper-inner quadrant of breast', 'Craniopharyngeal duct', 'Overlapping lesion of male genital organs', 'Floor of mouth NOS', 'Prostate gland', 'Long bones of lower limb and associated joints', 'Palate NOS', 'Retina', 'Eyelid', 'Lymph nodes of inguinal region or leg', 'Duodenum', 'Orbit NOS', 'Tonsillar pillar', 'Skin NOS', 'Cervical esophagus', 'Skin of other and unspecified parts of face', 'Peripheral nerves and autonomic nervous system of thorax', 'Peripheral nerves and autonomic nervous system of trunk NOS', 'Overlapping lesion of other and unspecified parts of mouth', 'Postcricoid region', 'Epididymis', 'Rib sternum clavicle and associated joints', 'Lymph nodes of head face and neck', 'Major salivary gland NOS', 'Islets of Langerhans', 'Anterior 2/3 of tongue NOS', 'Branchial cleft', 'Cranial nerve NOS', 'Connective subcutaneous and other soft tissues of upper limb and shoulder', 'Nervous system NOS', 'Cardia NOS', 'Occipital lobe', 'Overlapping lesion of vulva', 'Cauda equina', 'Paraurethral gland', 'Endometrium', 'Hepatic flexure of colon', 'Posterior mediastinum', 'Overlapping lesion of rectum anus and anal canal', 'Breast NOS', 'Middle ear', 'Overlapping lesion of esophagus', 'Overlapping lesion of palate', 'Thyroid gland', 'Short bones of lower limb and associated joints', 'Other ill-defined sites', 'Overlapping lesion of floor of mouth', 'Base of tongue NOS', 'Peripheral nerves and autonomic nervous system of abdomen', 'Overlapping lesion of hypopharynx', 'Bladder neck', 'Thoracic esophagus', 'Blood', 'Lateral wall of nasopharynx', 'Undescended testis', 'Sigmoid colon', 'Upper lobe lung', 'Overlapping lesions of oropharynx', 'Oropharynx NOS', 'Peripheral nerves and autonomic nervous system of pelvis', 'Overlapping lesion of female genital organs', 'Spinal meninges', 'Ureter', 'Overlapping lesion of pancreas', 'Connective subcutaneous and other soft tissues of thorax', 'Lymph nodes of axilla or arm', 'Colon NOS', 'Nipple', 'Skin of upper limb and shoulder', 'Vertebral column', 'Other specified parts of female genital organs', 'Overlapping lesion of colon', 'Other specified parts of male genital organs', 'Penis NOS', 'Cecum', 'Small intestine NOS', 'Cerebrum', 'Esophagus NOS', 'Endocrine gland NOS', 'Endocervix', 'Submandibular gland', 'Trachea', 'Cerebral meninges', 'Placenta', 'Extrahepatic bile duct', 'Overlapping lesion of accessory sinuses', 'Pleura NOS', 'Bones of skull and face and associated joints', 'Gastrointestinal tract NOS', 'Overlapping lesion of brain', 'Skin of lower limb and hip', 'Middle lobe lung', 'Bone NOS', 'Lateral wall of oropharynx', 'Larynx NOS', 'Overlapping lesion of bones joints and articular cartilage', 'Pelvis NOS', 'Gum NOS', 'Anterior wall of nasopharynx', 'Prepuce', '']","Biospecimen Type -is- ""Tissue Biospecimen Type"" || Biospecimen Type -is- ""Urine Biospecimen Type"" || Biospecimen Type -is- ""Bone Marrow Biospecimen Type""",Biospecimen
+Specimen Laterality,Specimen Laterality,SpecimenLaterality,"For tumors in paired organs, designates the side on which the specimen was obtained.",False,True,"['Not Applicable', 'Not Reported', 'Left', 'unknown', 'Right', 'Bilateral', '']","Biospecimen Type -is- ""Tissue Biospecimen Type"" || Biospecimen Type -is- ""Urine Biospecimen Type"" || Biospecimen Type -is- ""Bone Marrow Biospecimen Type""",Biospecimen
+Section Number in Sequence,Section Number in Sequence,SectionNumberinSequence,"Numeric value (integer, including ranges) provided to a sample in a series of sections (list all adjacent sections in the Adjacent Biospecimen IDs field)",False,True,,"Biospecimen Type -is- ""Tissue Biospecimen Type"" || Biospecimen Type -is- ""Bone Marrow Biospecimen Type""",Biospecimen
+Histologic Morphology Code,Histologic Morphology Code,HistologicMorphologyCode,"Histologic Morphology Code, based on ICD-O-3. Any valid ICD-O-3 morphology code. See https://seer.cancer.gov/icd-o-3/ and https://seer.cancer.gov/icd-o-3/sitetype.icdo3.20200629.xlsx. Examples: 80510",False,True,,"Biospecimen Type -is- ""Tissue Biospecimen Type"" || Biospecimen Type -is- ""Urine Biospecimen Type"" || Biospecimen Type -is- ""Bone Marrow Biospecimen Type""",Biospecimen
+Ischemic Time,Ischemic Time,IschemicTime,"Duration of time, in seconds, between when the specimen stopped receiving oxygen and when it was preserved or processed. Integer value.",False,True,,"Biospecimen Type -is- ""Tissue Biospecimen Type"" || Biospecimen Type -is- ""Analyte Biospecimen Type"" || Biospecimen Type -is- ""Urine Biospecimen Type"" || Biospecimen Type -is- ""Bone Marrow Biospecimen Type""",Biospecimen
+Portion Weight,Portion Weight,PortionWeight,"Numeric value that represents the sample portion weight, measured in milligrams.",False,True,,"Biospecimen Type -is- ""Tissue Biospecimen Type"" || Biospecimen Type -is- ""Urine Biospecimen Type"" || Biospecimen Type -is- ""Bone Marrow Biospecimen Type""",Biospecimen
+Preservation Method,Preservation Method,PreservationMethod,Text term that represents the method used to preserve the sample.,False,True,"['Fresh dissociated', 'Fresh dissociated and single cell sorted', 'Cryopreservation in dry ice - dead tissue', 'Formalin fixed-unbuffered', 'Snap Frozen', 'Fresh', 'Cryopreservation in liquid nitrogen - live cells', 'Cryopreserved', 'Liquid Nitrogen', 'Not Reported', 'Fresh dissociated and single cell sorted into plates in NP40 buffer', 'Methacarn fixed paraffin embedded - MFPE', 'Fresh dissociated and single cell sorted into plates', 'unknown', 'Formalin fixed-buffered', 'OCT', 'Formalin fixed paraffin embedded - FFPE', 'Frozen', 'Negative 80 Deg C', 'Cryopreservation in liquid nitrogen - dead tissue', '']","Biospecimen Type -is- ""Tissue Biospecimen Type"" || Biospecimen Type -is- ""Urine Biospecimen Type"" || Biospecimen Type -is- ""Bone Marrow Biospecimen Type""",Biospecimen
+Ischemic Temperature,Ischemic Temperature,IschemicTemperature,Specify whether specimen experienced warm or cold ischemia.,False,True,"['4C wet ice', 'Warm Ischemia', 'Liquid Nitrogen', 'Cold Ischemia', 'Negative -20C', 'unknown', 'Dry Ice', 'Ambient air', '']","Biospecimen Type -is- ""Tissue Biospecimen Type"" || Biospecimen Type -is- ""Analyte Biospecimen Type"" || Biospecimen Type -is- ""Urine Biospecimen Type"" || Biospecimen Type -is- ""Bone Marrow Biospecimen Type""",Biospecimen
+Tumor Tissue Type,Tumor Tissue Type,TumorTissueType,Text that describes the kind of disease present in the tumor specimen as related to a specific timepoint (add rows to select multiple values along with timepoints),False,True,"['Metastatic', 'Post therapy', 'Post therapy neoadjuvant', 'Primary', 'Normal adjacent', 'Premalignant - in situ', 'Atypia - hyperplasia', 'Premalignant', 'Local recurrence', 'Recurrent', 'Normal distant', 'Normal', 'Not Otherwise Specified', 'Additional Primary', 'Post therapy adjuvant', '']","Biospecimen Type -is- ""Tissue Biospecimen Type"" || Biospecimen Type -is- ""Urine Biospecimen Type"" || Biospecimen Type -is- ""Bone Marrow Biospecimen Type""",Biospecimen
+Slide Charge Type,Slide Charge Type,SlideChargeType,A description of the charge on the glass slide.,False,True,"['Charged', 'Not applicable', 'Uncharged', 'Other', 'Coverslip', '']","Biospecimen Type -is- ""Analyte Biospecimen Type""",Biospecimen
+Section Thickness Value,Section Thickness Value,SectionThicknessValue,"Numeric value to describe the thickness of a slice to tissue taken from a biospecimen, measured in microns (um).",False,True,,"Biospecimen Type -is- ""Analyte Biospecimen Type""",Biospecimen
+Analyte Type,Analyte Type,AnalyteType,The kind of molecular specimen analyte: a molecular derivative (I.e. RNA / DNA / Protein Lysate) obtained from a specimen,False,True,"['PBMCs or Plasma or Serum Analyte', 'DNA Analyte', 'cfDNA Analyte', 'RNA Analyte', 'PBMCs', 'Total RNA Analyte', 'Tissue Section Analyte', 'Serum Analyte', 'cDNA Libraries Analyte', 'Plasma', 'Tissue Block Analyte', '']","Biospecimen Type -is- ""Analyte Biospecimen Type""",Biospecimen
+Fixation Duration,Fixation Duration,FixationDuration,"The length of time, from beginning to end, required to process or preserve biospecimens in fixative (measured in minutes)",False,True,,"Biospecimen Type -is- ""Analyte Biospecimen Type""",Biospecimen
+Sectioning Days from Index,Sectioning Days from Index,SectioningDaysfromIndex,Number of days from the research participant's index date that the biospecimen was sectioned after collection,False,True,,"Biospecimen Type -is- ""Analyte Biospecimen Type""",Biospecimen
+Shipping Condition Type,Shipping Condition Type,ShippingConditionType,Text descriptor of the shipping environment of a biospecimen.,False,True,"['Dry Ice', 'Liquid Nitrogen', 'Not Shipped', 'Ice Pack', 'Other Shipping Environment', 'Specimen at Room Temperature', 'Ambient Pack', 'Cold Pack', '']","Biospecimen Type -is- ""Analyte Biospecimen Type"" || Biospecimen Type -is- ""Blood Biospecimen Type""",Biospecimen
+Total Volume Unit,Total Volume Unit,TotalVolumeUnit,Unit of measurement used for the total amount of sample or specimen,False,,"['cm^2', 'mL', 'mm^3', '']",,Biospecimen
+Dimensions Unit,Dimensions Unit,DimensionsUnit,"Unit of measurement used for dimension CDEs in metric system (i.e. cm, mm, etc)",False,,"['cm', 'mm', '']",,Biospecimen
+HTAN Participant ID,HTAN Participant ID,HTANParticipantID,HTAN ID associated with a patient based on HTAN ID SOP (eg HTANx_yyy ),True,,,,Demographics
+Days to Birth,Days to Birth,DaystoBirth,Number of days between the date used for index and the date from a person's date of birth represented as a calculated negative number of days.,False,,,,Demographics
+Country of Residence,Country of Residence,CountryofResidence,Country of Residence at enrollment,False,,"['India', 'Anguilla', 'Palau', 'Dominican Republic', 'Belgium', 'Barbados', 'Estonia', 'Liberia', 'Papua New Guinea', 'Saint Vincent and the Grenadines', 'Sierra Leone', 'Montserrat', 'Netherlands', 'Kenya', 'Canada', 'Svalbard & Jan Mayen Islands', 'Cuba', 'Tajikistan', 'Federated States of Micronesia', 'Guam', 'Bhutan', 'Malawi', 'Nauru', 'New Zealand', 'Tonga', 'Zambia', 'Holy See', 'Mozambique', 'Egypt', 'Belize', 'Ireland', 'France', 'Cyprus', 'Puerto Rico', 'Spain', 'Turkmenistan', 'Saint Lucia', 'Algeria', 'Thailand', 'Eswatini', 'Marshall Islands', 'Guadeloupe', 'Mauritius', 'Malaysia', 'Greenland', 'Kyrgyzstan', 'Faroe Islands', 'Poland', 'Georgia', 'Cambodia', 'Isle of Man', 'United Arab Emirates', 'South Korea', 'Niue', 'Namibia', 'Timor-Leste', ""Cote d'Ivoire"", 'Montenegro', 'Morocco', 'Bangladesh', 'Haiti', 'Norway', 'Guatemala', 'Slovenia', 'Burkina Faso', 'Vanuatu', 'El Salvador', 'Uzbekistan', 'Virgin Islands British', 'Guinea', 'China', 'San Marino', 'Finland', 'Honduras', 'Iraq', 'Oman', 'Saudi Arabia', 'Somalia', 'Azerbaijan', 'Rwanda', 'Greece', 'Djibouti', 'Liechtenstein', 'United Kingdom', 'Mauritania', 'Nepal', 'Latvia', 'Bahamas', 'Vietnam', 'Comoros', 'Martinique', 'Kosovo', 'Portugal', 'Reunion', 'Lebanon', 'Congo', 'Aruba', 'Gambia', 'Dominica', 'Falkland Islands (Malvinas)', 'Wallis and Futuna', 'Guinea-Bissau', 'New Caledonia', 'Tuvalu', 'South Sudan', 'Seychelles', 'Benin', 'Denmark', 'Paraguay', 'Suriname', 'Uganda', 'Italy', 'Malta', 'Western Sahara', 'Slovakia', 'Central African Republic', 'Solomon Islands', 'Hong Kong', 'Israel', 'Kiribati', 'Fiji', 'Russia', 'Singapore', 'Saint Helena Ascension and Tristan da Cunha', 'Sweden', 'Romania', 'North Macedonia', 'State of Palestine', 'Bolivia', 'Northern Mariana Islands', 'Armenia', 'Serbia', 'Peru', 'Sri Lanka', 'Sudan', 'Tokelau', 'Moldova', 'Jordan', 'Croatia', 'Uruguay', 'Cameroon', 'Chile', 'Grenada', 'Antigua and Barbuda', 'United States', 'Eritrea', 'Austria', 'Jamaica', 'Samoa', 'Tunisia', 'Mexico', 'North Korea', 'Yemen', 'Curacao', 'Madagascar', 'Philippines', 'Zimbabwe', 'Turkey', 'Cayman Islands', 'Libya', 'Maldives', 'Saint Pierre and Miquelon', 'Bosnia and Herzegovina', 'Gibraltar', 'Brazil', 'Monaco', 'Bermuda', 'Cape Verde', 'Botswana', 'Iran', 'Saint Kitts and Nevis', 'Trinidad and Tobago', 'Ghana', 'Ecuador', 'Mongolia', 'Venezuela', 'Czech Republic (Czechia)', 'Niger', 'Switzerland', 'Sao Tome and Principe', 'Macau', 'Belarus', 'Japan', 'Pakistan', 'Afghanistan', 'Mayotte', 'Ethiopia', 'Panama', 'Lithuania', 'Costa Rica', 'Bahrain', 'Guernsey', 'Bulgaria', 'Indonesia', 'Chad', 'Nicaragua', 'Guyana', 'Iceland', 'Brunei', 'Luxembourg', 'Lesotho', 'Colombia', 'Jersey', 'Equatorial Guinea', 'Kazakhstan', 'French Polynesia', 'Qatar', 'Ukraine', 'Angola', 'Cook Islands', 'Albania', 'South Africa', 'Andorra', 'Australia', 'Germany', 'Virgin Islands U.S.', 'Kuwait', 'Gabon', 'Argentina', 'Hungary', 'Syria', 'Tanzania', 'Senegal', 'French Guiana', 'Laos', 'Taiwan', 'Togo', 'Burundi', 'Myanmar', 'Mali', 'Democratic Republic of the Congo', 'Nigeria', '']",,Demographics
+Gender,Gender,Gender,"Text designations that identify gender. Gender is described as the assemblage of properties that distinguish people on the basis of their societal roles. [Identification of gender is based upon self-report and may come from a form, questionnaire, interview, etc.]",True,,"['Not Reported', 'unspecified', 'male', 'female', 'unknown']",,Demographics
+Occupation Duration Years,Occupation Duration Years,OccupationDurationYears,The number of years a patient worked in a specific occupation.,False,,,,Demographics
+Premature At Birth,Premature At Birth,PrematureAtBirth,The yes/no/unknown indicator used to describe whether the patient was premature (less than 37 weeks gestation) at birth.,False,,"['Not Reported', 'Yes', 'No', 'unknown', '']",,Demographics
+Vital Status,Vital Status,VitalStatus,The survival state of the person registered on the protocol.,True,,"['Dead', 'Not Reported', 'unknown', 'Alive']",,Demographics
+Age Is Obfuscated,Age Is Obfuscated,AgeIsObfuscated,The age of the patient has been modified for compliance reasons. The actual age differs from what is reported. Other date intervals for this patient may also be modified.,False,,"['True', 'False', '']",,Demographics
+Weeks Gestation at Birth,Weeks Gestation at Birth,WeeksGestationatBirth,Numeric value used to describe the number of weeks starting from the approximate date of the biological mother's last menstrual period and ending with the birth of the patient.,False,,,,Demographics
+Ethnicity,Ethnicity,Ethnicity,"An individual's self-described social and cultural grouping, specifically whether an individual describes themselves as Hispanic or Latino. The provided values are based on the categories defined by the U.S. Office of Management and Business and used by the U.S. Census Bureau.",True,,"['Not Reported', 'not hispanic or latino', 'hispanic or latino', 'unknown', 'not allowed to collect']",,Demographics
+Component,Component,Component,"Category of metadata (e.g. Diagnosis, Biospecimen, scRNA-seq Level 1, etc.); provide the same one for all items/rows.",True,,,,Demographics
+Race,Race,Race,"An arbitrary classification of a taxonomic group that is a division of a species. It usually arises as a consequence of geographical isolation withina a species and is characterized by shared heredity, physical attributes and behavior, and in the case of humans, by common history, nationality, or geographic distribution.",True,,"['Other', 'Not Reported', 'american indian or alaska native', 'black or african american', 'asian', 'white', 'native hawaiian or other pacific islander', 'unknown', 'not allowed to collect']",,Demographics
+Year Of Birth,Year Of Birth,YearOfBirth,Numeric value to represent the calendar year in which an individual was born.,False,,,,Demographics
+Cause of Death,Cause of Death,CauseofDeath,The cause of death,False,True,"['Renal Disorder NOS', 'Not Cancer Related', 'Not Reported', 'Toxicity', 'Cardiovascular Disorder NOS', 'Infection', 'Surgical Complications', 'Not Applicable', 'Cancer Related', 'unknown', 'Spinal Muscular Atrophy', 'End-stage Renal Disease', '']","Vital Status -is- ""Dead""",Demographics
+Days to Death,Days to Death,DaystoDeath,Number of days between the date used for index and the date from a person's date of death represented as a calculated number of days.,False,True,,"Vital Status -is- ""Dead""",Demographics
+Cause of Death Source,Cause of Death Source,CauseofDeathSource,The text term used to describe the source used to determine the patient's cause of death.,False,True,"['Autopsy', 'Death Certificate', 'Not Reported', 'Social Security Death Index', 'Medical Record', 'unknown', '']","Vital Status -is- ""Dead""",Demographics
+Year of Death,Year of Death,YearofDeath,Numeric value to represent the year of the death of an individual.,False,True,,"Vital Status -is- ""Dead""",Demographics
+Component,Component,Component,"Category of metadata (e.g. Diagnosis, Biospecimen, scRNA-seq Level 1, etc.); provide the same one for all items/rows.",True,,,,Patient
+HTAN Participant ID,HTAN Participant ID,HTANParticipantID,HTAN ID associated with a patient based on HTAN ID SOP (eg HTANx_yyy ),True,,,,Patient
+Pixels BigEndian,Pixels BigEndian,PixelsBigEndian,Boolean (True/False),True,,"['False', 'True']",,ImagingLevel3
+Component,Component,Component,"Category of metadata (e.g. Diagnosis, Biospecimen, scRNA-seq Level 1, etc.); provide the same one for all items/rows.",True,,,,ImagingLevel3
+PhysicalSizeX,PhysicalSizeX,PhysicalSizeX,Physical size (X-dimension) of a pixel. Units are set by PhysicalSizeXUnit. Floating point value > 0.,True,,,,ImagingLevel3
+DimensionOrder,DimensionOrder,DimensionOrder,The order in which the individual planes of data are interleaved.,True,,"['XYZCT', 'XYTZC', 'XYCTZ', 'XYCZT', 'XYZTC', 'ZYX']",,ImagingLevel3
+Software and Version,Software and Version,SoftwareandVersion,Name of software used to generate expression values. String,True,,,,ImagingLevel3
+SizeX,SizeX,SizeX,Size of image: X dimension (in pixels). Integer >= 1,True,,,,ImagingLevel3
+SizeC,SizeC,SizeC,Number of channels. Integer >= 1,True,,,,ImagingLevel3
+SizeY,SizeY,SizeY,Size of image: Y dimension (in pixels). Integer >= 1,True,,,,ImagingLevel3
+Imaging Object Class Description,Imaging Object Class Description,ImagingObjectClassDescription,Free text description of object class [string],True,,,,ImagingLevel3
+PlaneCount,PlaneCount,PlaneCount,"Number of Z-planes (not to be confused with downsampled ""pyramid""). Integer >=1",True,,,,ImagingLevel3
+HTAN Participant ID,HTAN Participant ID,HTANParticipantID,HTAN ID associated with a patient based on HTAN ID SOP (eg HTANx_yyy ),True,,,,ImagingLevel3
+Image ID,Image ID,ImageID,"Unique internal image identifier. eg ""Image:0"". (To be extracted from OME-XML)",True,,,,ImagingLevel3
+Imaging Data Type,Imaging Data Type,ImagingDataType,Specifies if data is a segmentation mask or image,True,,"['Mask', 'Image']",,ImagingLevel3
+SizeT,SizeT,SizeT,Number of time points. Integer >= 1,True,,,,ImagingLevel3
+Passed QC,Passed QC,PassedQC,Did all channels pass QC (if not add free text Comment),True,,"['No - Channels QC', 'Yes']",,ImagingLevel3
+Imaging Object Class,Imaging Object Class,ImagingObjectClass,Defines the structure that the mask deliniates,True,,"['nucleus', 'cytoplasm', 'Imaging Object Class Other', 'whole cell', 'plasma membrane']",,ImagingLevel3
+FOV number,FOV number,FOVnumber,Index of FOV (as it pertains to its sequence order). Integer >= 1,False,,,,ImagingLevel3
+Commit SHA,Commit SHA,CommitSHA,"Short SHA for software version [8 hexadecimal characters (for github), comma separated if multiple]",False,,,,ImagingLevel3
+Filename,Filename,filename,Name of a file ,True,,,,ImagingLevel3
+Parameter file,Parameter file,Parameterfile,Filename of a text file listing algorithm version numbers and relevant parameters needed to reproduce the analysis,True,,,,ImagingLevel3
+PhysicalSizeY,PhysicalSizeY,PhysicalSizeY,Physical size (Y-dimension) of a pixel. Units are set by PhysicalSizeYUnit. Floating point value > 0.,True,,,,ImagingLevel3
+HTAN Parent Biospecimen ID,HTAN Parent Biospecimen ID,HTANParentBiospecimenID,HTAN Biospecimen Identifier (eg HTANx_yyy_zzz) indicating the biospecimen(s) from which these files were derived; multiple parent biospecimen should be comma-separated,True,,,,ImagingLevel3
+Maximum intensity display range,Maximum intensity display range,Maximumintensitydisplayrange,Normalized upper-bound intensity value [numeric],False,,,,ImagingLevel3
+PixelType,PixelType,PixelType,"Data type for each pixel value. E.g. ""uint16""",True,,"['uint8', 'int8', 'float', 'int16', 'int32', 'bit', 'double', 'uint32', 'uint16']",,ImagingLevel3
+Frame Averaging,Frame Averaging,FrameAveraging,"Number of frames averaged together (if no averaging, set to 1). Integer >= 1",False,,,,ImagingLevel3
+SizeZ,SizeZ,SizeZ,Size of image: Z dimension (in pixels). Integer >= 1,True,,,,ImagingLevel3
+HTAN Data File ID,HTAN Data File ID,HTANDataFileID,Self-identifier for this data file - HTAN ID of this file HTAN ID SOP (eg HTANx_yyy_zzz),True,,,,ImagingLevel3
+FOVY,FOVY,FOVY,Field  of view Y dimension. Floating point value,False,,,,ImagingLevel3
+File Format,File Format,fileFormat,"Format of a file (e.g. txt, csv, fastq, bam, etc.)",True,,"['pdf', 'OME-TIFF', 'seg', 'doc', 'hyperlink', 'RData', 'idx', 'gff3', 'locs', 'bigwig', 'bai', 'gct', 'tiff', 'dat', 'maf', 'bed', 'tif', 'csv', 'DICOM', 'zip', 'czi', 'bpm', 'tagAlign', 'mzML', 'bed narrowPeak', 'hdf5', 'svs', 'png', 'tranches', 'jpg', 'sqlite', 'cell am', 'Python script', 'plink', 'avi', 'bam', 'excel', 'powerpoint', 'fig', 'dup', 'pzfx', 'svg', 'mex', 'recal', 'chp', 'mpg', 'Sentrix descriptor file', 'xml', 'sam', 'abf', 'idat', 'bed broadPeak', 'sdf', '7z', 'R script', 'sif', 'bcf', 'bgzip', 'gtf', 'json', 'md', 'bedgraph', 'cel', 'm', 'tsv', 'rmd', 'txt', 'tar', 'sra', 'fastq', 'mov', 'html', 'mtx', 'cloupe', 'ab1', 'wiggle', 'hic', 'sav', 'bed gappedPeak', 'flagstat', 'gzip', 'fasta', 'msf', 'raw', 'am', 'vcf']",,ImagingLevel3
+Minimum intensity display range,Minimum intensity display range,Minimumintensitydisplayrange,Normalized lower-bound intensity value [numeric ],False,,,,ImagingLevel3
+FOVX,FOVX,FOVX,Field of view X dimension. Floating point,False,,,,ImagingLevel3
+PhysicalSizeZ,PhysicalSizeZ,PhysicalSizeZ,Physical size (Z-dimension) of a pixel. Units are set by PhysicalSizeZUnit. Floating point value > 0.,True,,,,ImagingLevel3
+PhysicalSizeXUnit,PhysicalSizeXUnit,PhysicalSizeXUnit,The units of the physical size of a pixel. See OME enumeration of allowed values for the UnitsLength attribute -- default: microns (um),False,,"['cm', 'µm', 'Å', 'mm', 'nm', '']",,ImagingLevel3
+Object class,Object class,Objectclass,TBD,False,,,,ImagingLevel3
+PhysicalSizeYUnit,PhysicalSizeYUnit,PhysicalSizeYUnit,The units of the physical size of a pixel. See OME enumeration of allowed values for the UnitsLength attribute -- default: microns (um),False,,"['cm', 'µm', 'Å', 'mm', 'nm', '']",,ImagingLevel3
+FOVYUnit,FOVYUnit,FOVYUnit,Field of view Y dimension units. See OME enumeration of allowed values for the UnitsLength attribute -- default: microns (um),False,,"['cm', 'µm', 'Å', 'mm', 'nm', '']",,ImagingLevel3
+FOVXUnit,FOVXUnit,FOVXUnit,Field of view X dimension units. See OME enumeration of allowed values for the UnitsLength attribute -- default: microns (um),False,,"['cm', 'µm', 'Å', 'mm', 'nm', '']",,ImagingLevel3
+PhysicalSizeZUnit,PhysicalSizeZUnit,PhysicalSizeZUnit,TBD,False,,,,ImagingLevel3
+Comment,Comment,Comment,Free text field (generally for QC comment),False,True,,"Passed QC -is- ""No - Channels QC""",ImagingLevel3
+File Format,File Format,fileFormat,"Format of a file (e.g. txt, csv, fastq, bam, etc.)",True,,"['pdf', 'idx', 'dup', 'cell am', 'doc', 'maf', 'recal', 'abf', 'raw', 'fastq', 'gzip', 'txt', 'hic', 'tsv', 'seg', 'cel', 'tagAlign', 'tar', 'sra', 'bpm', 'R script', 'wiggle', 'RData', 'bcf', 'bed', 'html', 'bed narrowPeak', 'json', 'png', 'rmd', 'hdf5', 'sdf', 'md', 'fig', 'bed broadPeak', 'DICOM', 'czi', 'sam', 'flagstat', 'Python script', 'bgzip', 'am', 'ab1', 'mtx', 'mov', 'fasta', 'mzML', 'excel', 'csv', 'locs', 'vcf', 'bai', 'xml', 'gtf', 'sif', 'svs', 'idat', 'tiff', 'jpg', 'sqlite', 'm', 'gff3', 'bed gappedPeak', 'cloupe', 'tranches', 'zip', 'Sentrix descriptor file', 'bam', 'chp', 'hyperlink', 'gct', 'msf', 'powerpoint', 'plink', '7z', 'avi', 'tif', 'mex', 'dat', 'sav', 'OME-TIFF', 'bedgraph', 'mpg', 'bigwig', 'svg', 'pzfx']",,ScRNA-seqLevel3
+Cell Median Number Reads,Cell Median Number Reads,CellMedianNumberReads,Median number of reads per cell. Number,True,,,,ScRNA-seqLevel3
+Cell Total,Cell Total,CellTotal,Number of sequenced  cells. Applies to raw counts matrix only.,True,,,,ScRNA-seqLevel3
+Workflow End Datetime,Workflow End Datetime,WorkflowEndDatetime,A combination of date and time of day in the form [-]CCYY-MM-DDThh:mm:ss[Z|(+|-)hh:mm],False,,,,ScRNA-seqLevel3
+Matrix Type,Matrix Type,MatrixType,Type of data stored in matrix.,True,,"['Normalized Counts', 'Batch Corrected Counts', 'Raw Counts', 'Scaled Counts']",,ScRNA-seqLevel3
+HTAN Parent Data File ID,HTAN Parent Data File ID,HTANParentDataFileID,HTAN Data File Identifier indicating the file(s) from which these files were derived,True,,,,ScRNA-seqLevel3
+HTAN Data File ID,HTAN Data File ID,HTANDataFileID,Self-identifier for this data file - HTAN ID of this file HTAN ID SOP (eg HTANx_yyy_zzz),True,,,,ScRNA-seqLevel3
+scRNAseq Workflow Type,scRNAseq Workflow Type,ScRNAseqWorkflowType,Generic name for the workflow used to analyze a data set.,True,,"['STARsolo', 'SEQC', 'DEXSeq', 'HTSeq - FPKM', 'dropEST', 'CellRanger', 'HCA Optimus', 'Differentiation trajectory analysis', 'Cufflinks', 'Cell annotation', 'Other']",,ScRNA-seqLevel3
+Workflow Version,Workflow Version,WorkflowVersion,Major version of the workflow (e.g. Cell Ranger v3.1),True,,,,ScRNA-seqLevel3
+Data Category,Data Category,DataCategory,Specific content type of the data file.,True,,"['Other', 'Splice Junction Quantification', 'Exon Expression Quantification', 'Transcript Expression', 'Isoform Expression Quantification', 'Gene Expression', 'Gene Expression Quantification']",,ScRNA-seqLevel3
+Cell Median Number Genes,Cell Median Number Genes,CellMedianNumberGenes,Median number of genes detected per cell. Number,True,,,,ScRNA-seqLevel3
+scRNAseq Workflow Parameters Description,scRNAseq Workflow Parameters Description,ScRNAseqWorkflowParametersDescription,"Parameters used to run the workflow. scRNA-seq level 3: e.g. Normalization and log transformation, ran empty drops or doublet detection, used filter on # genes/cell, etc. scRNA-seq Level 4: dimensionality reduction with PCA and 50 components, nearest-neighbor graph with k = 20 and Leiden clustering with resolution = 1, UMAP visualization using 50 PCA components, marker genes used to annotate cell types, information about droplet matrix (all barcodes) to cell matrix (only informative barcodes representing real cells) conversion",True,,,,ScRNA-seqLevel3
+Workflow Link,Workflow Link,WorkflowLink,Link to workflow or command. DockStore.org recommended. URL,True,,,,ScRNA-seqLevel3
+Linked Matrices,Linked Matrices,LinkedMatrices,All matrices associated with every part of a SingleCellExperiment object. Comma-delimited list of filenames,False,,,,ScRNA-seqLevel3
+Workflow Start Datetime,Workflow Start Datetime,WorkflowStartDatetime,A combination of date and time of day in the form [-]CCYY-MM-DDThh:mm:ss[Z|(+|-)hh:mm],False,,,,ScRNA-seqLevel3
+Filename,Filename,filename,Name of a file ,True,,,,ScRNA-seqLevel3
+Component,Component,Component,"Category of metadata (e.g. Diagnosis, Biospecimen, scRNA-seq Level 1, etc.); provide the same one for all items/rows.",True,,,,ScRNA-seqLevel3
+Sentinel Node Positive Assessment Count,Sentinel Node Positive Assessment Count,SentinelNodePositiveAssessmentCount,The number or amount of metastatic neoplasms related to the confirmed presence of disease or specific microorganisms during examination of the first rounded mass of lymphatic tissue to which cancer is likely to spread from the primary tumor.,False,,,,ClinicalDataTier2
+Mismatch Repair System Status,Mismatch Repair System Status,MismatchRepairSystemStatus,The text that best describes the condition or state of MMR (mismatch repair system) in the patient,False,,"['Mismatch repair deficiency MMRD', 'Microsatellite stable MSS', 'Mismatch repair proficiency MMPP', 'unknown or other', 'Microsatellite instability high MSIH', '']",,ClinicalDataTier2
+COVID19 Occurrence Indicator,COVID19 Occurrence Indicator,COVID19OccurrenceIndicator,The indicator that describes whether or not a COVID-19 infectious disorder occurred.,False,,"['Not Done', 'Yes', 'No', 'unknown', 'Not Applicable', '']",,ClinicalDataTier2
+COVID19 Positive Lab Test Indicator,COVID19 Positive Lab Test Indicator,COVID19PositiveLabTestIndicator,The indicator that describes whether or not there was a COVID-19 positive test result.,False,,"['Not Done', 'Yes', 'No', 'unknown', 'Not Applicable', '']",,ClinicalDataTier2
+Education Level,Education Level,EducationLevel,Highest level of education that the patient completed (direct patient-derived information),False,,"[""Master's degree"", 'Data not available', 'Doctoral degree or professional degree', ""Bachelor's degree"", 'Grade school', 'Some college or associate degree', 'Not high school graduate', 'High school graduate (including equivalency)', 'Graduate or professional degree', 'No formal education', '']",,ClinicalDataTier2
+Second hand smoke exposure years,Second hand smoke exposure years,Secondhandsmokeexposureyears,The number of cumulative years of the patient's exposure to second-hand cigarette smoke,False,,,,ClinicalDataTier2
+Country of Birth,Country of Birth,CountryofBirth,Country where the patient was born.,False,,"['Zambia', 'Burundi', 'French Polynesia', 'Lithuania', 'Togo', 'Montenegro', 'Belize', 'Cook Islands', 'Faroe Islands', 'Czech Republic (Czechia)', 'Bahamas', 'Turkmenistan', 'Laos', 'Tonga', 'Bolivia', 'Equatorial Guinea', 'Holy See', 'Croatia', 'Myanmar', 'Kenya', 'Isle of Man', 'Anguilla', 'Gibraltar', 'Cyprus', 'Belarus', 'Jamaica', 'Honduras', 'Bahrain', 'San Marino', 'Guernsey', 'Mexico', 'Bangladesh', 'Albania', 'Chad', 'Cayman Islands', 'Malaysia', 'Oman', 'Seychelles', 'Uruguay', 'Ghana', 'Finland', 'Nigeria', 'North Korea', 'Dominica', 'Saint Helena Ascension and Tristan da Cunha', 'Saint Pierre and Miquelon', 'Serbia', 'Germany', 'Sweden', 'Yemen', 'Bosnia and Herzegovina', 'India', 'Taiwan', 'Guam', 'Trinidad and Tobago', 'Australia', 'Indonesia', 'Iceland', 'Chile', 'Cambodia', 'Senegal', 'Singapore', 'Pakistan', 'Armenia', 'Brazil', 'Thailand', 'Rwanda', 'Azerbaijan', 'Austria', 'Slovakia', 'Kyrgyzstan', 'Mali', 'Tuvalu', 'Botswana', 'Samoa', 'Guadeloupe', 'Portugal', 'Guinea-Bissau', 'Kuwait', 'Greenland', 'Svalbard & Jan Mayen Islands', 'Niger', 'Western Sahara', 'Virgin Islands British', 'Maldives', 'Bulgaria', 'North Macedonia', 'Saint Kitts and Nevis', 'Hong Kong', 'Nepal', 'Philippines', 'Switzerland', 'Tokelau', 'United States', 'Jordan', 'Bhutan', 'Jersey', 'Reunion', 'Suriname', 'French Guiana', 'Malawi', 'Kosovo', 'Macau', 'Denmark', 'Guyana', 'South Africa', 'Kiribati', 'Vietnam', ""Cote d'Ivoire"", 'Timor-Leste', 'Lebanon', 'Niue', 'Georgia', 'Puerto Rico', 'Japan', 'Saudi Arabia', 'Wallis and Futuna', 'Egypt', 'Israel', 'Malta', 'Federated States of Micronesia', 'Andorra', 'Solomon Islands', 'Norway', 'Sierra Leone', 'Ethiopia', 'Uganda', 'Vanuatu', 'Turkey', 'New Caledonia', 'Djibouti', 'Namibia', 'Cuba', 'Tanzania', 'Antigua and Barbuda', 'Poland', 'Romania', 'Saint Vincent and the Grenadines', 'Guatemala', 'Afghanistan', 'Mayotte', 'United Kingdom', 'Palau', 'Sao Tome and Principe', 'Aruba', 'Uzbekistan', 'Curacao', 'Algeria', 'Martinique', 'Northern Mariana Islands', 'Tajikistan', 'Marshall Islands', 'Falkland Islands (Malvinas)', 'Panama', 'Peru', 'Haiti', 'Ukraine', 'Bermuda', 'Burkina Faso', 'Gabon', 'France', 'unknown', 'Lesotho', 'Luxembourg', 'Iraq', 'Sudan', 'State of Palestine', 'Ireland', 'Guinea', 'Iran', 'Cameroon', 'Syria', 'Zimbabwe', 'United Arab Emirates', 'South Korea', 'Colombia', 'Qatar', 'Nauru', 'China', 'Morocco', 'Angola', 'Barbados', 'Italy', 'Monaco', 'Mauritania', 'Grenada', 'Mauritius', 'Kazakhstan', 'Eritrea', 'Moldova', 'Ecuador', 'Netherlands', 'Saint Lucia', 'Montserrat', 'Cape Verde', 'Latvia', 'Somalia', 'Brunei', 'Comoros', 'Virgin Islands U.S.', 'Central African Republic', 'Paraguay', 'Venezuela', 'Gambia', 'Spain', 'Estonia', 'Costa Rica', 'Liechtenstein', 'Hungary', 'Greece', 'Fiji', 'Liberia', 'Benin', 'Nicaragua', 'Russia', 'Mozambique', 'Congo', 'South Sudan', 'Sri Lanka', 'Democratic Republic of the Congo', 'Canada', 'Tunisia', 'Papua New Guinea', 'El Salvador', 'Belgium', 'Dominican Republic', 'Madagascar', 'New Zealand', 'Slovenia', 'Argentina', 'Mongolia', 'Eswatini', 'Libya', '']",,ClinicalDataTier2
+Known Genetic Predisposition Mutation,Known Genetic Predisposition Mutation,KnownGeneticPredispositionMutation,A yes/no/unknown indicator to identify whether there is a known genetic predisposition mutation present in the patient.,False,,"['Yes', 'No', 'unknown', '']",,ClinicalDataTier2
+Tumor Extranodal Extension Indicator,Tumor Extranodal Extension Indicator,TumorExtranodalExtensionIndicator,The indicator to determine extranodal involvement or extent of the disease.,False,,"['NO', 'Not sampled or dissected', 'Present - minimal', 'Indeterminate', 'YES', 'Not applicable', 'Absent', 'unspecified', 'Present', 'UNKNOWN', 'No source documentation', 'Present - extensive', '']",,ClinicalDataTier2
+Stop Days from Index,Stop Days from Index,StopDaysfromIndex,"Number of days from the date of birth (index date) to the end date of the event (e.g. exposure to environmental factor, treatment start, etc.). Note: if the event occurs at a single time point, e.g. a diagnosis or a lab test, the values for this column is 'Not Applicable'",False,,,,ClinicalDataTier2
+Concomitant Medication Received Type,Concomitant Medication Received Type,ConcomitantMedicationReceivedType,An enumerated list of the type of concomitant medication received by the patient.,False,,"['Anxiolytics or sedatives', 'COX-2 inhibitor', 'Lipid-lowering drugs', 'Antidepressants-weak CYP2D2 inhibitors or non-inhibitors', 'Non-prescription supplements for relief of hot flashes', 'Antidepressants-Strong CYP2D6 inhibitors', 'Opioids', 'Intravaginal estrogen preparations', 'Corticosteroid', 'Anticoagulant agents', 'Not Applicable', 'Anticonvulsant', 'Non-prescription supplements for memory', 'Tricyclic antidepressants', 'Diabetes-Insulin', 'Decadron', 'Prophylactic antiplatelet therapy', 'Antidepressants-Moderate CYP2D6 inhibitors', 'unknown', 'Other', 'Antifungal', 'Not Reported', 'Diabetes-Metformin containing agents', 'Antiplatelet agents', 'Non-steroidal anti-inflammatory agents', 'Prescription medications for relief of hot flashes', 'Growth factor', 'Aspirin', 'Prescription medications for memory', 'Bisphosphonates for treatment/prevention of bone loss', '']",,ClinicalDataTier2
+Mode of Cancer Detection,Mode of Cancer Detection,ModeofCancerDetection,"Text term used to describe the mode of cancer detection, like standard of care screening or random detection",False,,"['Data not available', 'Interval Cancer', 'Standard of Care Screening', 'Incidentaloma', 'Clinical Examination of unrelated cancer symptoms', '']",,ClinicalDataTier2
+Ecig vape use,Ecig vape use,Ecigvapeuse,"Use of non-traditional cigarette nicotine delivery device (electronic cigarette, ENDS - electronic nicotine delivery system)",False,,"['Current', 'Never', 'unknown', 'Former', '']",,ClinicalDataTier2
+COVID19 Current Status,COVID19 Current Status,COVID19CurrentStatus,The patient's current COVID-19 status of sign or symptom events or interventions,False,,"['Status unknown due to lack of disease/tumor assessment due to COVID-19 diagnosis', 'Patient had symptoms but now is fully recovered', 'Patient currently has symptoms', 'Status unknown due to other reasons', 'Patient never had any symptoms of COVID-19', 'Status unknown due to general COVID-19 related travel restrictions', '']",,ClinicalDataTier2
+Family Member Vital Status Indicator,Family Member Vital Status Indicator,FamilyMemberVitalStatusIndicator,The response indicates whether the family member of the patient with a history of cancer is alive. (Extension to GDC attributes in Family History Tier 1),False,,"['Vital Status Dead', 'Not Reported', 'Vital Status Alive', 'unknown', '']",,ClinicalDataTier2
+Hereditary Cancer Predisposition Syndrome,Hereditary Cancer Predisposition Syndrome,HereditaryCancerPredispositionSyndrome,History of presence of inherited genetic predisposition syndrome that confers heightened susceptibility to cancer in the patient.,False,,"['Rubinstein-Taybi syndrome', 'Hereditary renal oncocytoma', 'Tyrosinemia', 'Hereditary mixed polyposis syndrome', 'Hereditary melanoma', 'Serrated polyposis syndrome', 'Carney complex', 'Gorlin syndrome', 'Alpha-1 antitrypsin', 'Melanoma–astrocytoma syndrome', 'Familial gastrointestinal stromal tumor', 'Hereditary retinoblastoma', 'Familial renal cancer', 'Cowden syndrome', 'Hereditary diffuse gastric cancer', 'SDH associated renal cancer', 'Birt-Hogg-Dube syndrome', 'MUTYH-associated polyposis', 'Not Applicable', 'Tuberous sclerosis complex', 'Familial adenomatous polyposis', 'Hereditary paraganglioma–pheochromocytoma syndrome', 'Glycogen Storage Disease', 'Hereditary breast–ovarian cancer syndrome', 'Juvenile polyposis syndrome', 'von Hippel-Lindau Syndrome', 'unknown', 'Biliary disorder', 'Constitutional mismatch repair deficiency', 'Hereditary leiomyoma-renal cell carcinoma', 'Not Reported', 'Attenuated familial adenomatous polyposis', 'Cirrhosis unknown etiology', 'Turcot syndrome', 'Fanconi anemia', 'Familial prostate cancer', 'Rhabdoid tumor predisposition syndrome type I', 'Beckwith-Wiedemann', 'Li-Fraumeni syndrome', 'BAP1 mutant disease', 'Nevoid basal cell carcinoma syndrome', 'Hereditary papillary RCC', 'Familial pancreatic cancer', 'Hereditary papillary renal cell carcinoma', 'Multiple endocrine neoplasia type II', 'Peutz–Jeghers syndrome', 'Rhabdoid tumor predisposition syndrome type II', 'Multiple endocrine neoplasia type I', 'Lynch syndrome', '']",,ClinicalDataTier2
+Mutational Signatures,Mutational Signatures,MutationalSignatures,"Mutational signatures identified in the patient, includes signatures linked to selected exogenous carcinogens, endogenous and enzymatic modification of DNA or defective DNA repair. Note: Include only outputs of tests that were completed clinically for the participant and only include data from a diagnostic array that was completed prior to research sequencing was done. ",False,,"['Signature 13', 'Signature 17', 'Tobacco use associated mutations', 'Signature 14', 'Activation Induced Deaminases (AID) associated mutations', 'age of cancer diagnosis', 'Signature 2', 'Signature 11', 'Data not available', 'Signature 21', 'Signature 12', 'Signature 19', 'Signature 1A', 'Signature 9', 'Alkylating Agents (Temozolomide) induced mutations', 'UV light induced mutations', 'APOBEC enzymes associated mutations', 'Not Applicable', 'Signature 1B', 'Signature 5', 'Signature 7', 'methylated CpG sequences mutagenesis(deamination of 5-methyl-cytosine)', 'Signature 16', 'Signature 15', 'unknown', 'Signature 3', 'Other', 'Not Reported', 'localized substitution hypermutation (kataegis)', 'microsatellite instability (additions and deletions)', 'Signature 6', 'transcriptional strand bias', 'Signature 20', 'DNA MMR Deficiency', 'Signature 8', 'Ig gene hypermutation', 'Signature 10', 'Signature 18', 'altered activity of the error-prone polymerase POLε (POLE)', 'Signature 4', '']",,ClinicalDataTier2
+Cancer Incidence Location,Cancer Incidence Location,CancerIncidenceLocation,"The county and state in which the patient lives and to which the cancer_incidence data correlates. Record as ""County, State"" as they appear in the incidence box from which the cancer_incidence data is obtained in the https://gis.cancer.gov/canceratlas/tableview/ website",False,,,,ClinicalDataTier2
+Ecig vape times per day,Ecig vape times per day,Ecigvapetimesperday,e-cig frequency of use (times per day—one “time” consists of around 15 puffs or lasts around 10 minutes),False,,,,ClinicalDataTier2
+Rural vs Urban,Rural vs Urban,RuralvsUrban,"Density of population in the county of residence, based on census data (updated last on 4/28/20). Use patient zip code to find the county the patient lives in by going to https://www.unitedstateszipcodes.org/. Enter the zip code in the main text field and use the associated county on the right side of the result field. Go to https://www2.census.gov/programs-surveys/acs/data/covid_19/Data_Profiles_for_HHS/050-County_By_State/. Select the dp02_XX.csv file where XX = the two letter abbreviation for the appropriate state. On row 166 find the total population for the appropriate county.  If the total population is <2,500 enter a value of ""Rural Population""; if 2,500 - 50,000 enter a value of ""Urban Cluster""; or if >50,000 enter ""Urban Population""",False,,"['Urban Population (population >50000)', 'Urban Cluster (population 2500 - 50000)', 'Rural Population (population <2500)', '']",,ClinicalDataTier2
+Type of smoke exposure cumulative years,Type of smoke exposure cumulative years,Typeofsmokeexposurecumulativeyears,The number of cumulative years of the patient's specific type of smoke exposure,False,,,,ClinicalDataTier2
+Start Days from Index,Start Days from Index,StartDaysfromIndex,"Number of days from the date of birth (index date) to the date of an event (e.g. exposure to environmental factor, treatment start, etc.). If not applicable please enter 'Not Applicable'",True,,,,ClinicalDataTier2
+Sentinel Lymph Node Count,Sentinel Lymph Node Count,SentinelLymphNodeCount,Numeric count of sentinel lymph nodes.,False,,,,ClinicalDataTier2
+Other Biopsy Resection Site,Other Biopsy Resection Site,OtherBiopsyResectionSite,A description of the location on or within the human body where the surgical biopsy/resection procedure was performed (Not covered under HTAN Clinical Data Tier 1),False,,,,ClinicalDataTier2
+COVID19 Antibody Testing,COVID19 Antibody Testing,COVID19AntibodyTesting,Text term that demonstrates the test results of immunoglobulin M (IgM) and immunoglobulin G (IgG) antibodies to the SARS-CoV-2 virus in subject serum samples.,False,,"['SARS-CoV-2 IgG antibody positive', 'Not Done', 'SARS-CoV-2 IgG/IgM antibody negative', 'unknown', 'SARS-CoV-2 IgM antibody positive', 'SARS-CoV-2 IgG antibody negative', 'SARS-CoV-2 IgM antibody negative', 'Not Applicable', 'SARS-CoV-2 IgG/IgM antibody positive', '']",,ClinicalDataTier2
+Component,Component,Component,"Category of metadata (e.g. Diagnosis, Biospecimen, scRNA-seq Level 1, etc.); provide the same one for all items/rows.",True,,,,ClinicalDataTier2
+Extent of Tumor Resection,Extent of Tumor Resection,ExtentofTumorResection,"The degree to which the lesion has been cut out, or resected.",False,,"['Extensive Subtotal', 'Suboptimal', 'Optimal debulking', 'Partial debulking', 'Subtotal Resection', 'unknown', 'Segmental', 'Other', 'Not Reported', 'Open Biopsy', 'Gross Total Resection', 'Minor', 'Not Applicable', 'Suboptimal debulking', 'NTR', '']",,ClinicalDataTier2
+Ecig vape 30 day use num,Ecig vape 30 day use num,Ecigvape30dayusenum,Number of days e-cigarettes or vaping device was used in the last 30 days,False,,,,ClinicalDataTier2
+Prior Sites of Radiation,Prior Sites of Radiation,PriorSitesofRadiation,The anatomic location to which radiation treatment was administered to a patient prior to enrollment on a protocol.,False,,"['Back', 'Bowel', 'Lip', 'Venous', 'Aorta', 'Adenoid', 'Mediastinal Soft Tissue', 'Retina', 'Scapula', 'Esophagus', 'Carotid Artery', 'Lymph Node(s) Cervical', 'Abdomen total', 'Ileum', 'Thumb', 'Clitoris', 'Skin trunk local', 'Gallbladder', 'Mediastinum', 'Chest Wall', 'Lymph Node(s) Occipital', 'Jejunum', 'Neck', 'Primary Tumor Field', 'Ischium', 'Wrist', 'Bladder', 'Parametrium', 'Lymph Node(s) Mesenteric', 'Cerebellum', 'Floor of Mouth', 'Lymph Node(s) Scalene', 'Cartilage', 'Ocular Orbits', 'Rectosigmoid Junction', 'Mesothelium', 'Lymph Node(s) Regional', 'Parathyroid', 'Peritoneal Cavity', 'Lymph Node(s) Mediastinal', 'Soft Tissue', 'Broad Ligament', 'Shoulder', 'Primary tumor site', 'Rectum', 'Vas Deferens', 'Uvula', 'Not Reported', 'Cerebral Cortex', 'Frontal Cortex', 'Nasal Cavity', 'Cardia', 'Nerve(s) Cranial', 'Ascending Colon', 'Nails', 'Ankle', 'Joint', 'Cervix', 'Sternum', 'Cerebrum', 'Fibroblasts', 'Forehead', 'Femoral Artery', 'Blood', 'Calf', 'Connective Tissue', 'Bronchiole', 'Endocrine Gland', 'Eye', 'Placenta', 'Pouch', 'Sciatic Nerve', 'Muscle', 'Adrenal', 'Umbilical Cord', 'Carotid Body', 'Foreskin', 'Head Face Or Neck Nos', 'Aortic Body', 'Lymph Node(s) Mammary', 'Retro-Orbital Region', 'Ampulla of Vater', 'Nasal Soft Tissue', 'Popliteal Fossa', 'Cerebrospinal Fluid', 'Ear Pinna (External)', 'Leg', 'Lymph Node(s) Iliac-Common', 'Index Finger', 'Lymph Node(s) Inguinal', 'Lymph Node(s) Retroperitoneal', 'Amniotic Fluid', 'Testis', 'Head and Neck', 'Ovary', 'Vagina', 'Lymph Node(s) Subclavicular', 'Peritoneum', 'Maxilla', 'Esophagus Mucosa Only', 'Fibula', 'Lymph Node(s) Internal Mammary', 'Urinary Tract', 'Brain', 'Pleura', 'Lymph Node(s) Epitrochlear', 'Subcutaneous Tissue', 'Tongue', 'Brow', 'Mantle', 'Body total', 'Hard Palate', 'Ascites', 'Laryngopharynx', 'Alveolar Ridge', 'Lymph Node(s) Femoral', 'Salivary Gland', 'Oral Cavity Mucosa Only', 'Epididymis', 'Fundus of Stomach', 'Seminal Vesicle', 'Bone', 'Other', 'Islet Cells', 'Hippocampus', 'Oral Cavity', 'Bone non-spine', 'Sinus(es) Maxillary', 'Spine', 'Small Bowel', 'Colon Mucosa Only', 'Lumbar Spine', 'Ring Finger', 'Abdominal Wall', 'Blood Vessel', 'Stomach Mucosa Only', 'Lacrimal Gland', 'Bone Marrow', 'Femur', 'Skin', 'Skin total', 'Mandible', 'Tibia', 'Pancreas', 'Skull', 'Dermal', 'Skin lower extremity local', 'Lymph Node(s) Submandibular', 'Mitochondria', 'Lymph Node(s) Paraaortic', 'Spinal Column', 'Ilium', 'Pineal Gland', 'Ligament', 'Cell-Line', 'Stomach', 'Parotid Gland', 'Omentum', 'Brain Stem', 'Prostate', 'Lymph Node(s) Popliteal', 'Skin upper extremity local', 'Foot', 'Middle Finger', 'Vein', 'Leptomeninges', 'Periorbital Soft Tissue', 'Jaw', 'Pericardium', 'Regional Site', 'Spinal Cord', 'Urethra', 'Descending Colon', 'Vulva', 'Lymph Node(s) Iliac-External', 'Artery', 'Pharynx', 'Lymph Node(s) Distant', 'Thyroid', 'Hand', 'Finger', 'Anal Sphincter', 'Trunk', 'Cervical Spine', 'Lymph Node(s) Splenic', 'Frontal Lobe', 'Hip', 'Gastroesophageal Junction', 'Prostate Bed', 'Gum', 'Thorax', 'unknown', 'Central Nervous System', 'Arm', 'Appendix', 'Penis', 'Transverse Colon', 'Fluid', 'Tonsil', 'Thoracic Spine', 'Ureter', 'Skeletal Muscle', 'Temporal Cortex', 'Lymph Node(s) Axilla', 'Pituitary Gland', 'Clavicle', 'Antecubital Fossa', 'Fallopian Tube', 'Kidney', 'Epitrochlear', 'Mesentery', 'Lymph Node(s) Parotid', 'Lymph Node(s) Hilar', 'Trachea / Major Bronchi', 'Groin', 'Distant Site', 'Splenic Flexure', 'Auditory Canal', 'Tendon', 'Liver', 'Larynx', 'Esophagogastric Junction', 'Spleen', 'Ganglia', 'Capillary', 'Pylorus', 'White Blood Cells', 'Buttock', 'Knee', 'Anus', 'Paraspinal Ganglion', 'Anorectum', 'Diaphragm', 'Ear Canal', 'Scalp', 'Chest', 'Axilla', 'Buccal Mucosa', 'Chin', 'Hepatic Duct', 'Gastrointestinal Tract', 'Humerus', 'Large Bowel', 'Ascending Colon Hepatic Flexure', 'Hilar', 'Thymus', 'Oropharynx', 'Pelvis', 'Round Ligament', 'Forearm', 'Retroperitoneum', 'Tonsil (Pharyngeal)', 'Pineal', 'Scrotum', 'Small Bowel Mucosa Only', 'Acetabulum', 'Nasopharynx', 'Conjunctiva', 'Heart', 'Elbow', 'Occipital Cortex', 'Sacrum', 'Femoral Vein', 'Throat', 'Palate', 'Autonomic Nervous System', 'Patella', 'Nerve', 'Ear', 'Hepatic', 'Adipose', 'Synovium', 'Buccal Cavity', 'Gastrointestinal Intestine', 'Aqueous Fluid', 'Rib', 'Colon', 'Ileocecal Valve', 'Thigh', 'Vertebra', 'Genitourinary NOS', 'Lymph Node(s) Supraclavicular', 'Antrum', 'Hepatic Vein', 'Sinus', 'Lymph Node(s) Pelvic', 'Common Duct', 'Breast', 'Uterus', 'Lung', 'Carina', 'Bronchus', 'Cecum', 'Duodenum', 'Bile Duct', 'Epidural Space', 'Hypopharynx', 'Prostate Seminal Vesicles and Lymph Nodes', 'Small Finger', 'Sigmoid Colon', 'Lymph Node', '']",,ClinicalDataTier2
+Cancer Associated Gene Mutations,Cancer Associated Gene Mutations,CancerAssociatedGeneMutations,Type of inherited germline or other gene mutations that confers heightened susceptibility to cancer identified in patient history,False,,"['BLM mutation', 'SMARCB1 mutation', 'BMPR1A mutation', 'SDHD mutation', 'KRAS mutation', 'BAP1 mutation', 'ATRX mutation', 'H3K27M mutation', 'SDHB mutation', 'APC mutation', 'H3G34R/V mutation', 'SDHAF2 mutation', 'KIT mutation', 'MLH1 mutation', 'CHK mutation', 'TSC2 mutation', 'HOXB13 mutation', 'CDH1 mutation', 'MET mutation', 'PAX5 mutation', 'EGFR mutation', 'IKZF1 mutation', 'ALK mutation', 'FLCN mutation', 'CDKN2A mutation', 'ROS1 mutation', 'MUTYH mutation', 'NF1 mutation', 'BRCA1 mutation', 'ETV6 mutation', 'Not Applicable', 'PTEN mutation', 'VHL mutation', 'BRAF mutation', 'PRKAR1A mutation', 'ARF mutation', 'NF2 mutation', 'MSH2 mutation', 'ACVR1 mutation', 'SMARCA4 mutation', 'CDKN2A and p14ARF mutation', 'unknown', 'p14ARF mutation', 'PALB2 mutation', 'Not Reported', 'TP53 mutation', 'PMS2 mutation', 'PHOX2B mutation', 'PolE mutation', 'MAX mutation', 'PTCH mutation', 'TSC1 mutation', 'BRCA1 and 2 mutation', 'POT1 mutation', 'STK11 mutation', 'RET mutation', 'MEN1 mutation', 'ATM mutation', 'RB1 mutation', 'SDHC mutation', 'MSH6 mutation', 'FH mutation', 'PDGFRA mutation', 'PolD mutation', 'SETD2 mutation', 'SMAD4 mutation', 'BRCA2 mutation', 'GREM1 mutation', 'TMEM127 mutation', '']",,ClinicalDataTier2
+Medically Underserved Area,Medically Underserved Area,MedicallyUnderservedArea,"Areas or populations designated by HRSA as having too few primary care providers, high infant mortality, high poverty or a high elderly population:  Use patient zip code to find the county the patient lives in by going to https://www.unitedstateszipcodes.org/ - enter the zip code in the main text field and use the associated county on the right side of the result field. Go to data.hrsa.gov website and select ""Query Data"". Pick the Medically Underserved Areas/Populations (MUA/P) data source in the step 1 menu and select ""View Data"". Enter the name of the county (_______ county) in the first ""Service Area"" column, adding the state in the 5th column may help direct you to the data.  If the designation type in the third column is ""medically underserved area"" enter ""Yes"" as the value. If the county generates a ""No data available in table"" enter ""No"" as the value.  A value of ""Unknown"" indicates that sufficient data was not available to look up the value.  If value is yes, complete the Medically_underserved_score data element.",False,,"['Medically Underserved Area - Yes', 'Medically Underserved Area - Unknown', 'Medically Underserved Area - No', '']",,ClinicalDataTier2
+Timepoint Label,Timepoint Label,TimepointLabel,"Label to identify the time point at which the clinical data or biospecimen was obtained (e.g. Baseline, End of Treatment, Overall survival, Final). NO PHI/PII INFORMATION IS ALLOWED.",True,,,,ClinicalDataTier2
+HTAN Participant ID,HTAN Participant ID,HTANParticipantID,HTAN ID associated with a patient based on HTAN ID SOP (eg HTANx_yyy ),True,,,,ClinicalDataTier2
+Lab Tests for MMR Status,Lab Tests for MMR Status,LabTestsforMMRStatus,Laboratory tests used to evaluate the status of mismatch repair pathways,False,,"['BRAF\xa0sequencing', 'PCR to evaluate microsatellite instability', 'unknown', 'Other', 'Not Applicable', 'MLH1\xa0promoter methylation analysis', 'IHC staining for mismatch repair proteins', '']",,ClinicalDataTier2
+Precancerous Condition Type,Precancerous Condition Type,PrecancerousConditionType,The classification of pre-cancerous cells found in a specific collection of data being studied by the Consortium for Molecular and Cellular Characterization of Screen-Detected Lesions (MCL).,False,,"['Prostatic Intraepithelial Neoplasia', 'Invasive melanoma', 'Mild dysplasia', 'Atypical melanocytic proliferation', 'Acral-lentiginous', 'Melanocytic hyperplasia', 'Superficial spreading', 'Atypical adenomatous hyperplasia', 'Adenocarcinoma in situ - mucinous', 'Moderate dysplasia', 'Hamartoma', 'Adenocarcinoma in situ - non mucinous', 'Invasive melanoma - desmoplastic', 'Squamous metaplasia - immature', 'Invasive melanoma - acral lentiginous', 'Ductal Carcinoma In Situ', 'Invasive melanoma - lentigo maligna', 'Lentigo maligna type', 'Melanoma in situ not otherwise classified', 'Atypical Adenomatous Lung Hyperplasia', 'Severe dysplasia', 'Invasive melanoma - nodular type', 'Benign tumor NOS', 'Scar - no residual melanoma', 'Other', 'Normal WDA', 'Reserve cell hyperplasia', 'Melanoma in situ', 'Pancreatic Intraductal Papillary-Mucinous Neoplasm', 'Carcinoma NOS', 'Pancreatic Intraepithelial Neoplasia', 'Squamous metaplasia - mature', 'Invasive melanoma - superficial spreading', 'No diagnosis possible', 'Invasive melanoma - nevoid', 'Melanoma in situ arising in a giant congenital nevus', 'Persistent melanoma in situ', '']",,ClinicalDataTier2
+Immunosuppression,Immunosuppression,Immunosuppression,The indicator that describes whether or not immunosuppressive therapy was administered.,False,,"['Not Done', 'Yes', 'No', 'unknown', 'Not Applicable', '']",,ClinicalDataTier2
+Satellite Metastasis Present Indicator,Satellite Metastasis Present Indicator,SatelliteMetastasisPresentIndicator,A yes/no indicator to ask if intransit metastases or satellite lesions are present.,False,,"['Yes', 'No', 'unknown', '']",,ClinicalDataTier2
+COVID19 Cancer Treatment Followup,COVID19 Cancer Treatment Followup,COVID19CancerTreatmentFollowup,Indicator that describes if cancer treatment was modified for the patient due to COVID-19 infectious disorder,False,,"['Yes', 'No', 'Not Applicable', 'unknown', '']",,ClinicalDataTier2
+Chewing tobacco daily use count,Chewing tobacco daily use count,Chewingtobaccodailyusecount,"The quantity of daily use of tobacco, in the form of a plug, usually flavored, for chewing rather than smoking.",False,,,,ClinicalDataTier2
+COVID19 Complications Severity,COVID19 Complications Severity,COVID19ComplicationsSeverity,Text term that retrospectively indicates the worst complications during COVID-19 infectious disorder in the patient.,False,,"['Pulmonary complications', 'Cardiac complications', 'unknown', 'Systemic complications', 'Other', 'Not Applicable', '']",,ClinicalDataTier2
+Cancer Incidence,Cancer Incidence,CancerIncidence,"Incidence of specific cancer type in a defined area (a number between 0 and 100). The rate of incident cases per population of 100,000 persons of a specific type of cancer as designated in the ""primary_diagnosis"" data element in the county where the patient resides, using the most recent 2013-2017 NCI Cancer Atlas derived data.  Use patient zip code to find the county the patient lives in by going to https://www.unitedstateszipcodes.org/. Enter the zip code in the main text field and use the asociated county on the right side of the result field. On the https://gis.cancer.gov/canceratlas/tableview/ website, choose ""Incidence"" from the Topic dropdown menu, state of interest from the Area menu, ""All Races"" from the Race menu, and the cancer type (""Both Sexes"" when possible) from the Statistic menu. Find the county of interest and enter the numeric Age-Adjusted Rate per 100,000 as the value.",False,,,,ClinicalDataTier2
+Medically Underserved Score,Medically Underserved Score,MedicallyUnderservedScore,"Index of Medical Underservice (IMU) score, a number between 0 and 100, where 0 represents completely underserved and 100 represents best served or least underserved. Use patient zip code to find the county the patient lives in by going to https://www.unitedstateszipcodes.org/. Enter the zip code in the main text field and use the asociated county on the right side of the result field. Go to data.hrsa.gov website and select Query Data. Pick the Medically Underserved Areas/Populations (MUA/P) data source in the step 1 menu and select View Data. Enter the name of the county (______ county) in the first ""Service Area"" column, adding the state in the 5th column may help direct you to the data. Enter the Index of Medical Underservice Score in the fourth column to one decimal place as the value.",False,True,,"Medically Underserved Area -is- ""Medically Underserved Area - Yes""",ClinicalDataTier2
+Component,Component,Component,"Category of metadata (e.g. Diagnosis, Biospecimen, scRNA-seq Level 1, etc.); provide the same one for all items/rows.",True,,,,BulkRNA-seqLevel2
+Contamination,Contamination,Contamination,Fraction of reads coming from cross-sample contamination collected from GATK4. Number,False,,,,BulkRNA-seqLevel2
+Alignment Workflow Url,Alignment Workflow Url,AlignmentWorkflowUrl,Link to workflow used for read alignment. DockStore.org recommended. String,True,,,,BulkRNA-seqLevel2
+MSI Status,MSI Status,MSIStatus,MSIsensor determination of either microsatellite stability or instability.,False,,"['MSI-low', 'MSI-high', 'MSS', 'MSI', '']",,BulkRNA-seqLevel2
+Index File Name,Index File Name,IndexFileName,The name (or part of a name) of a file (of any type). String,True,,,,BulkRNA-seqLevel2
+Total Reads,Total Reads,TotalReads,Total number of reads per sample. Integer,False,,,,BulkRNA-seqLevel2
+Proportion Reads Duplicated,Proportion Reads Duplicated,ProportionReadsDuplicated,Proportion of duplicated reads collected from samtools. Number,False,,,,BulkRNA-seqLevel2
+MSI Score,MSI Score,MSIScore,Numeric score denoting the aligned reads file's MSI score from MSIsensor. Number,False,,,,BulkRNA-seqLevel2
+Genomic Reference,Genomic Reference,GenomicReference,Exact version of the human genome reference used in the alignment of reads (e.g. https://www.gencodegenes.org/human/),True,,,,BulkRNA-seqLevel2
+Short Reads,Short Reads,ShortReads,Number of reads that were too short. Integer,False,,,,BulkRNA-seqLevel2
+HTAN Data File ID,HTAN Data File ID,HTANDataFileID,Self-identifier for this data file - HTAN ID of this file HTAN ID SOP (eg HTANx_yyy_zzz),True,,,,BulkRNA-seqLevel2
+Alignment Workflow Type,Alignment Workflow Type,AlignmentWorkflowType,Generic name for the workflow used to analyze a data set.,True,,"['STAR 2-Pass', 'STAR 2-Pass Genome', 'BWA-mem', 'STAR 2-Pass Transcriptome', 'BWA with BQSR', 'BWA with Mark Duplicates and BQSR', 'STAR 2-Pass Chimeric', 'Other Alignment Workflow', 'BWA', 'BWA-aln']",,BulkRNA-seqLevel2
+MSI Workflow Link,MSI Workflow Link,MSIWorkflowLink,Link to method workflow (or command) used in estimating the MSI. URL,False,,,,BulkRNA-seqLevel2
+Total Unmapped reads,Total Unmapped reads,TotalUnmappedreads,Number of reads that did not map to genome. Integer,False,,,,BulkRNA-seqLevel2
+Mean Coverage,Mean Coverage,MeanCoverage,"Mean coverage for whole genome sequencing, or mean target coverage for whole exome and targeted sequencing, collected from Picard. Number",False,,,,BulkRNA-seqLevel2
+Genomic Reference URL,Genomic Reference URL,GenomicReferenceURL,Link to human genome sequence (e.g. ftp://ftp.ebi.ac.uk/pub/databases/gencode/Gencode_human/release_34/GRCh38.primary_assembly.genome.fa.gz) [URL],True,,,,BulkRNA-seqLevel2
+Contamination Error,Contamination Error,ContaminationError,Estimation error of cross-sample contamination collected from GATK4. Number,False,,,,BulkRNA-seqLevel2
+Average Insert Size,Average Insert Size,AverageInsertSize,Average insert size collected from samtools. Integer,False,,,,BulkRNA-seqLevel2
+Pairs On Diff CHR,Pairs On Diff CHR,PairsOnDiffCHR,Pairs on different chromosomes collected from samtools. Integer,False,,,,BulkRNA-seqLevel2
+File Format,File Format,fileFormat,"Format of a file (e.g. txt, csv, fastq, bam, etc.)",True,,"['png', 'powerpoint', 'ab1', 'bpm', 'doc', 'tar', 'abf', 'idat', 'mov', 'bigwig', 'bcf', 'mpg', 'hdf5', 'sra', 'mex', 'tagAlign', 'tiff', 'excel', 'dup', 'mzML', 'maf', 'csv', 'avi', 'svg', 'm', 'md', 'RData', 'hyperlink', 'raw', 'cloupe', 'txt', 'pdf', 'recal', 'sdf', 'tif', 'sqlite', 'flagstat', 'R script', 'bed gappedPeak', 'mtx', 'xml', 'bam', 'tranches', 'OME-TIFF', 'plink', 'msf', 'fig', 'locs', 'bai', 'seg', 'fasta', 'gzip', 'fastq', 'rmd', 'cell am', 'dat', 'pzfx', 'hic', 'am', 'bed narrowPeak', 'gct', 'cel', 'bed broadPeak', 'tsv', 'czi', 'bed', 'sam', 'idx', 'jpg', '7z', 'gff3', 'wiggle', 'svs', 'sav', 'Sentrix descriptor file', 'bgzip', 'sif', 'html', 'json', 'bedgraph', 'DICOM', 'chp', 'zip', 'gtf', 'vcf', 'Python script']",,BulkRNA-seqLevel2
+Average Base Quality,Average Base Quality,AverageBaseQuality,Average base quality collected from samtools. Number,False,,,,BulkRNA-seqLevel2
+Average Read Length,Average Read Length,AverageReadLength,Average read length collected from samtools. Integer,False,,,,BulkRNA-seqLevel2
+Total Uniquely Mapped,Total Uniquely Mapped,TotalUniquelyMapped,Number of reads that map to genome. Integer,False,,,,BulkRNA-seqLevel2
+Proportion Reads Mapped,Proportion Reads Mapped,ProportionReadsMapped,Proportion of mapped reads collected from samtools. Number,False,,,,BulkRNA-seqLevel2
+Proportion,Proportion,Proportion,TBD,False,,,,BulkRNA-seqLevel2
+Proportion Base Mismatch,Proportion Base Mismatch,ProportionBaseMismatch,Proportion of mismatched bases collected from samtools. Number,False,,,,BulkRNA-seqLevel2
+Targets No Coverage,Targets No Coverage,TargetsNoCoverage,TBD,False,,,,BulkRNA-seqLevel2
+Filename,Filename,filename,Name of a file ,True,,,,BulkRNA-seqLevel2
+HTAN Parent Data File ID,HTAN Parent Data File ID,HTANParentDataFileID,HTAN Data File Identifier indicating the file(s) from which these files were derived,True,,,,BulkRNA-seqLevel2
+Custom Alignment Workflow,Custom Alignment Workflow,CustomAlignmentWorkflow,Specify the name of a custom alignment workflow,False,True,,"Alignment Workflow Type -is- ""Other Alignment Workflow""",BulkRNA-seqLevel2
+Timepoint Label,Timepoint Label,TimepointLabel,"Label to identify the time point at which the clinical data or biospecimen was obtained (e.g. Baseline, End of Treatment, Overall survival, Final). NO PHI/PII INFORMATION IS ALLOWED.",True,,,,NeuroblastomaandGliomaTier3
+CNS Tumor Primary Anatomic Site,CNS Tumor Primary Anatomic Site,CNSTumorPrimaryAnatomicSite,Primary tumor location in the central nervous system that comprise the tissues of the central nervous system (brain and spinal cord)-not covered in Tiers 1 and 2,False,,"['Hippocampus', 'Paraspinal ganglion', 'Ventricles', 'Spinal cord-Lumbar', 'Suprasellar/Hypothalamic/Pituitary', 'Cerebellar/Posterior fossa', 'Brainstem-Pons', 'Spinal cord-Thoracic', 'Other locations NOS', 'Intracranial/Leptomeningeal', 'Thalamus', 'Meninges/Dura', 'Spinal cord-Cervical', 'Other lymph nodes', 'Optic pathway', 'Brain stem-Midbrain/Tectum', 'Brain stem-Medulla', 'Basal ganglia', '']",,NeuroblastomaandGliomaTier3
+Stop Days from Index,Stop Days from Index,StopDaysfromIndex,"Number of days from the date of birth (index date) to the end date of the event (e.g. exposure to environmental factor, treatment start, etc.). Note: if the event occurs at a single time point, e.g. a diagnosis or a lab test, the values for this column is 'Not Applicable'",False,,,,NeuroblastomaandGliomaTier3
+Glioma Specific Radiation Field,Glioma Specific Radiation Field,GliomaSpecificRadiationField,A description of the location on or within the CNS where radiation was administered in a partcipant with glioma,False,,"['Craniospinal', 'Focal-tumor bed', 'Not Applicable', 'unknown', '']",,NeuroblastomaandGliomaTier3
+Infra Tentorial Ependymoma Molecular Subgroup,Infra Tentorial Ependymoma Molecular Subgroup,InfraTentorialEpendymomaMolecularSubgroup,Text term to identify the molecular subgroup in a infra tentorial ependymoma,False,,"['unknown', 'Not Applicable', 'PF-EPN-B', 'PF-EPN-A', 'Myxopapillary ependymoma', '']",,NeuroblastomaandGliomaTier3
+Supra Tentorial Ependymoma Molecular Subgroup,Supra Tentorial Ependymoma Molecular Subgroup,SupraTentorialEpendymomaMolecularSubgroup,Text term to identify the molecular subgroup in a supra tentorial ependymoma,False,,"['ST-EPN-YAP1', 'ST-EPN-RELA', 'Not Applicable', 'unknown', '']",,NeuroblastomaandGliomaTier3
+Glioma Specific Metastasis Sites,Glioma Specific Metastasis Sites,GliomaSpecificMetastasisSites,Evidence of active brain metastasis including leptomeningeal involvement,False,,"['Brain', 'CSF', 'Not Applicable', 'Leptomeningeal', 'Spine', 'Bone marrow', 'Other', '']",,NeuroblastomaandGliomaTier3
+Neuroblastoma MYCN Gene Amplification Status,Neuroblastoma MYCN Gene Amplification Status,NeuroblastomaMYCNGeneAmplificationStatus,Neuroblastoma MYCN amplification or over-expression status,False,,"['unknown', 'Amplified', 'Not done', 'Not amplified', '']",,NeuroblastomaandGliomaTier3
+Component,Component,Component,"Category of metadata (e.g. Diagnosis, Biospecimen, scRNA-seq Level 1, etc.); provide the same one for all items/rows.",True,,,,NeuroblastomaandGliomaTier3
+HTAN Participant ID,HTAN Participant ID,HTANParticipantID,HTAN ID associated with a patient based on HTAN ID SOP (eg HTANx_yyy ),True,,,,NeuroblastomaandGliomaTier3
+Start Days from Index,Start Days from Index,StartDaysfromIndex,"Number of days from the date of birth (index date) to the date of an event (e.g. exposure to environmental factor, treatment start, etc.). If not applicable please enter 'Not Applicable'",True,,,,NeuroblastomaandGliomaTier3
+Library Layout,Library Layout,LibraryLayout,Sequencing read type,True,,"['Paired End', 'Single Read']",,BulkRNA-seqLevel1
+DV200,DV200,DV200,Represents the percentage of RNA fragments that are >200 nucleotides in size. Number,False,,,,BulkRNA-seqLevel1
+Kmer Content,Kmer Content,KmerContent,State classification given by FASTQC for the metric. Metric specific details about the states are available on their website.,False,,"['WARN', 'unknown', 'Not Reported', 'PASS', 'FAIL', '']",,BulkRNA-seqLevel1
+Read Indicator,Read Indicator,ReadIndicator,Indicate if this is Read 1 (R1) or Read 2 (R2),True,,"['R1&R2', 'R1', 'R2']",,BulkRNA-seqLevel1
+Fragment Maximum Length,Fragment Maximum Length,FragmentMaximumLength,"Maximum length of the sequenced fragments (e.g., as predicted by Agilent Bioanalyzer). Integer",False,,,,BulkRNA-seqLevel1
+Sequence Length Distribution,Sequence Length Distribution,SequenceLengthDistribution,State classification given by FASTQC for the metric. Metric specific details about the states are available on their website.,False,,"['WARN', 'unknown', 'Not Reported', 'PASS', 'FAIL', '']",,BulkRNA-seqLevel1
+Library Strand,Library Strand,LibraryStrand,Library stranded-ness.,False,,"['Not Applicable', 'Unstranded', 'Second Stranded', 'First Stranded', '']",,BulkRNA-seqLevel1
+Adapter Content,Adapter Content,AdapterContent,State classification given by FASTQC for the metric. Metric specific details about the states are available on their website.,False,,"['WARN', 'unknown', 'Not Reported', 'PASS', 'FAIL', '']",,BulkRNA-seqLevel1
+QC Workflow Type,QC Workflow Type,QCWorkflowType,Generic name for the workflow used to analyze a data set. String,False,,,,BulkRNA-seqLevel1
+Flow,Flow,Flow,TBD,False,,,,BulkRNA-seqLevel1
+Library Preparation Kit Version,Library Preparation Kit Version,LibraryPreparationKitVersion,Version of Library Preparation Kit. String,True,,,,BulkRNA-seqLevel1
+RIN,RIN,RIN,A numerical assessment of the integrity of RNA based on the entire electrophoretic trace of the RNA sample including the presence or absence of degradation products. Number,False,,,,BulkRNA-seqLevel1
+Per Sequence GC Content,Per Sequence GC Content,PerSequenceGCContent,State classification given by FASTQC for the metric. Metric specific details about the states are available on their website.,False,,"['WARN', 'unknown', 'Not Reported', 'PASS', 'FAIL', '']",,BulkRNA-seqLevel1
+Library Selection Method,Library Selection Method,LibrarySelectionMethod,How RNA molecules are isolated.,True,,"['Hybrid Selection', 'Poly-T Enrichment', 'rRNA Depletion', 'PCR', 'Other', 'miRNA Size Fractionation', 'Random', 'Affinity Enrichment']",,BulkRNA-seqLevel1
+Per Tile Sequence Quality,Per Tile Sequence Quality,PerTileSequenceQuality,State classification given by FASTQC for the metric. Metric specific details about the states are available on their website.,False,,"['WARN', 'unknown', 'Not Reported', 'PASS', 'FAIL', '']",,BulkRNA-seqLevel1
+Adapter Sequence,Adapter Sequence,AdapterSequence,Base sequence of the sequencing adapter. String,False,,,,BulkRNA-seqLevel1
+Lane Number,Lane Number,LaneNumber,"The basic machine unit for sequencing. For Illumina machines, this reflects the physical lane number. Wrong or missing information may affect analysis results. Integer",False,,,,BulkRNA-seqLevel1
+Total Reads,Total Reads,TotalReads,Total number of reads per sample. Integer,False,,,,BulkRNA-seqLevel1
+QC Workflow Link,QC Workflow Link,QCWorkflowLink,Link to workflow used. String,False,,,,BulkRNA-seqLevel1
+Fragment Minimum Length,Fragment Minimum Length,FragmentMinimumLength,"Minimum length of the sequenced fragments (e.g., as predicted by Agilent Bioanalyzer). Integer",False,,,,BulkRNA-seqLevel1
+Spike In,Spike In,SpikeIn,A set of known synthetic RNA molecules with known sequence that are added to the cell lysis mix,True,,"['PhiX', 'No Spike In', 'ERCC', 'Other Spike In']",,BulkRNA-seqLevel1
+Component,Component,Component,"Category of metadata (e.g. Diagnosis, Biospecimen, scRNA-seq Level 1, etc.); provide the same one for all items/rows.",True,,,,BulkRNA-seqLevel1
+Library Preparation Days from Index,Library Preparation Days from Index,LibraryPreparationDaysfromIndex,Number of days between sample for assay was received in lab and the libraries were prepared for sequencing [number],False,,,,BulkRNA-seqLevel1
+Size Selection Range,Size Selection Range,SizeSelectionRange,Range of size selection. String,False,,,,BulkRNA-seqLevel1
+File Format,File Format,fileFormat,"Format of a file (e.g. txt, csv, fastq, bam, etc.)",True,,"['gtf', 'tif', 'xml', 'cloupe', 'mov', 'bed narrowPeak', 'sam', 'msf', 'Sentrix descriptor file', 'mex', 'tagAlign', 'fastq', 'sav', 'svs', 'bedgraph', 'ab1', 'tiff', 'avi', 'json', 'bigwig', 'bed', 'sif', 'plink', 'wiggle', 'doc', 'gct', 'pzfx', 'fig', 'OME-TIFF', 'recal', 'chp', 'tsv', 'seg', 'hic', 'am', 'hyperlink', 'maf', 'pdf', 'bai', 'mpg', 'zip', 'bpm', 'html', 'jpg', 'mtx', 'cel', 'hdf5', 'dat', 'gzip', 'abf', 'flagstat', 'bed broadPeak', 'RData', 'locs', 'vcf', 'md', 'sdf', 'sqlite', 'gff3', 'cell am', 'csv', 'bgzip', 'svg', 'raw', 'rmd', 'excel', 'bed gappedPeak', 'mzML', 'dup', 'czi', 'tranches', 'DICOM', 'idx', 'idat', 'R script', 'm', 'Python script', '7z', 'powerpoint', 'bam', 'png', 'tar', 'sra', 'bcf', 'fasta', 'txt']",,BulkRNA-seqLevel1
+Basic Statistics,Basic Statistics,BasicStatistics,State classification given by FASTQC for the metric. Metric specific details about the states are available on their website.,False,,"['WARN', 'unknown', 'Not Reported', 'PASS', 'FAIL', '']",,BulkRNA-seqLevel1
+Sequencing Batch ID,Sequencing Batch ID,SequencingBatchID,Links samples to a specific local sequencer run. Can be string or 'null',True,,,,BulkRNA-seqLevel1
+Nucleic Acid Source,Nucleic Acid Source,NucleicAcidSource,The source of the input nucleic molecule,True,,"['Single Nucleus', 'Bulk Nuclei', 'Single Cell', 'Bulk Whole Cell']",,BulkRNA-seqLevel1
+HTAN Data File ID,HTAN Data File ID,HTANDataFileID,Self-identifier for this data file - HTAN ID of this file HTAN ID SOP (eg HTANx_yyy_zzz),True,,,,BulkRNA-seqLevel1
+Base Caller Name,Base Caller Name,BaseCallerName,Name of the base caller. String,False,,,,BulkRNA-seqLevel1
+Library Preparation Kit Name,Library Preparation Kit Name,LibraryPreparationKitName,Name of Library Preparation Kit. String,True,,,,BulkRNA-seqLevel1
+Cell Barcode,Cell Barcode,CellBarcode,TBD,False,,,,BulkRNA-seqLevel1
+Fragment Mean Length,Fragment Mean Length,FragmentMeanLength,"Mean length of the sequenced fragments (e.g., as predicted by Agilent Bioanalyzer). Number",False,,,,BulkRNA-seqLevel1
+To Trim Adapter Sequence,To Trim Adapter Sequence,ToTrimAdapterSequence,Does the user suggest adapter trimming?,False,,"['Yes - Trim Adapter Sequence', 'No', '']",,BulkRNA-seqLevel1
+HTAN Parent Biospecimen ID,HTAN Parent Biospecimen ID,HTANParentBiospecimenID,HTAN Biospecimen Identifier (eg HTANx_yyy_zzz) indicating the biospecimen(s) from which these files were derived; multiple parent biospecimen should be comma-separated,True,,,,BulkRNA-seqLevel1
+Read Length,Read Length,ReadLength,"The length of the sequencing reads. Can be integer, null",True,,,,BulkRNA-seqLevel1
+Encoding,Encoding,Encoding,Version of ASCII encoding of quality values found in the file. String,False,,,,BulkRNA-seqLevel1
+Sequencing Platform,Sequencing Platform,SequencingPlatform,A platform is an object aggregate that is the set of instruments and software needed to perform a process [OBI_0000050]. Specific model of the sequencing instrument.,True,,"['Illumina HiSeq X Ten', 'Illumina HiSeq X Five', 'AB SOLiD 3', 'Illumina MiSeq', 'Illumina Genome Analyzer II', 'Illumina HiSeq 2500', 'Illumina Next Seq 550', 'Other', 'Illumina Next Seq 2500', 'Complete Genomics', 'PacBio RS', 'Illumina NovaSeq 6000', 'NovaSeqS4', 'Ion Torrent PGM', 'unknown', 'NovaSeq 6000', 'Not Reported', 'Ion Torrent Proton', 'Illumina Genome Analyzer IIx', 'Illumina Next Seq 500', 'Ion Torrent S5', 'Illumina HiSeq 4000', 'Illumina HiSeq 2000', '454 GS FLX Titanium', 'AB SOLiD 4 AB SOLiD 2', 'Illumina NextSeq']",,BulkRNA-seqLevel1
+Fragment Standard Deviation Length,Fragment Standard Deviation Length,FragmentStandardDeviationLength,"Standard deviation of the sequenced fragments length (e.g., as predicted by Agilent Bioanalyzer). Number",False,,,,BulkRNA-seqLevel1
+Sequence Duplication Levels,Sequence Duplication Levels,SequenceDuplicationLevels,State classification given by FASTQC for the metric. Metric specific details about the states are available on their website.,False,,"['WARN', 'unknown', 'Not Reported', 'PASS', 'FAIL', '']",,BulkRNA-seqLevel1
+Per Base N Content,Per Base N Content,PerBaseNContent,State classification given by FASTQC for the metric. Metric specific details about the states are available on their website.,False,,"['WARN', 'unknown', 'Not Reported', 'PASS', 'FAIL', '']",,BulkRNA-seqLevel1
+Per Sequence Quality Score,Per Sequence Quality Score,PerSequenceQualityScore,State classification given by FASTQC for the metric. Metric specific details about the states are available on their website.,False,,"['WARN', 'unknown', 'Not Reported', 'PASS', 'FAIL', '']",,BulkRNA-seqLevel1
+Overrepresented Sequences,Overrepresented Sequences,OverrepresentedSequences,State classification given by FASTQC for the metric. Metric specific details about the states are available on their website.,False,,"['WARN', 'unknown', 'Not Reported', 'PASS', 'FAIL', '']",,BulkRNA-seqLevel1
+Percent GC Content,Percent GC Content,PercentGCContent,The overall %GC of all bases in all sequences. Integer,False,,,,BulkRNA-seqLevel1
+QC Workflow Version,QC Workflow Version,QCWorkflowVersion,Major version for a workflow. String,False,,,,BulkRNA-seqLevel1
+Multiplex Barcode,Multiplex Barcode,MultiplexBarcode,The barcode/index sequence used. Wrong or missing information may affect analysis results. String,False,,,,BulkRNA-seqLevel1
+Filename,Filename,filename,Name of a file ,True,,,,BulkRNA-seqLevel1
+Library Preparation Kit Vendor,Library Preparation Kit Vendor,LibraryPreparationKitVendor,Vendor of Library Preparation Kit. String,True,,,,BulkRNA-seqLevel1
+Transcript Integrity Number,Transcript Integrity Number,TranscriptIntegrityNumber,"Used to describe the quality of the starting material, esp. in regards to FFPE samples. Number",False,,,,BulkRNA-seqLevel1
+Adapter Name,Adapter Name,AdapterName,Name of the sequencing adapter. String,False,,,,BulkRNA-seqLevel1
+Per Base Sequence Quality,Per Base Sequence Quality,PerBaseSequenceQuality,State classification given by FASTQC for the metric. Metric specific details about the states are available on their website.,False,,"['WARN', 'unknown', 'Not Reported', 'PASS', 'FAIL', '']",,BulkRNA-seqLevel1
+Per Base Sequence Content,Per Base Sequence Content,PerBaseSequenceContent,State classification given by FASTQC for the metric. Metric specific details about the states are available on their website.,False,,"['WARN', 'unknown', 'Not Reported', 'PASS', 'FAIL', '']",,BulkRNA-seqLevel1
+Target Depth,Target Depth,TargetDepth,The targeted read depth prior to sequencing. Integer,False,,,,BulkRNA-seqLevel1
+Base Caller Version,Base Caller Version,BaseCallerVersion,Version of the base caller. String,False,,,,BulkRNA-seqLevel1
+Spike In Mix 1,Spike In Mix 1,SpikeInMix1,TBD,False,True,,"Spike In -is- ""ERCC""",BulkRNA-seqLevel1
+Both Spike in Mixes,Both Spike in Mixes,BothSpikeinMixes,TBD,False,True,,"Spike In -is- ""ERCC""",BulkRNA-seqLevel1
+Spike In Concentration,Spike In Concentration,SpikeInConcentration,The final concentration or dilution (for commercial sets) of the spike in mix [PMID:21816910],False,True,,"Spike In -is- ""ERCC""",BulkRNA-seqLevel1
+Spike In Mix 2,Spike In Mix 2,SpikeInMix2,TBD,False,True,,"Spike In -is- ""ERCC""",BulkRNA-seqLevel1
+Excitation Bandwidth,Excitation Bandwidth,ExcitationBandwidth,Nominal width of excitation spectrum (nm),False,,,,ImagingLevel2Channels
+Channel Name,Channel Name,ChannelName,This must match the corresponding field in the OME-XML / TIFF header. (eg “Blue” or “CD45” or “E-cadherin”),True,,,,ImagingLevel2Channels
+Lot,Lot,Lot,Lot number from vendor,False,,,,ImagingLevel2Channels
+Dilution,Dilution,Dilution,Dilution (eg 1:1000),False,,,,ImagingLevel2Channels
+Emission Bandwidth,Emission Bandwidth,EmissionBandwidth,Nominal width of emission spectrum (nm),False,,,,ImagingLevel2Channels
+Channel Passed QC,Channel Passed QC,ChannelPassedQC,Identify stains that did not pass QC but are included in the dataset.,True,,"['Yes', 'No']",,ImagingLevel2Channels
+Cycle Number,Cycle Number,CycleNumber,The cycle # in which the co-listed reagent(s) was(were) used. Integer >= 1 (up to number of cycles),False,,,,ImagingLevel2Channels
+Concentration,Concentration,Concentration,Concentration (eg 10ug/mL),False,,,,ImagingLevel2Channels
+Emission Wavelength,Emission Wavelength,EmissionWavelength,Center/peak of the emission spectrum (nm),False,,,,ImagingLevel2Channels
+Antibody Name,Antibody Name,AntibodyName,"Antibody Name (free text (eg “Keratin”, “CD163”, “DNA”))",False,,,,ImagingLevel2Channels
+Oligo Barcode Lower Strand,Oligo Barcode Lower Strand,OligoBarcodeLowerStrand,Oligo Barcode - Lower Strand,False,,,,ImagingLevel2Channels
+Channel ID,Channel ID,ChannelID,"This must match the corresponding field in the OME-XML / TIFF header. (eg ""Channel:0:1"")",True,,,,ImagingLevel2Channels
+Fluorophore,Fluorophore,Fluorophore,Fluorescent dye label (eg Alexa Fluor 488),False,,,,ImagingLevel2Channels
+Catalog Number,Catalog Number,CatalogNumber,Catalog Number,False,,,,ImagingLevel2Channels
+Vendor,Vendor,Vendor,Vendor,False,,,,ImagingLevel2Channels
+RRID identifier,RRID identifier,RRIDidentifier,Research Resource Identifier (eg “RRID: AB_394606”),False,,,,ImagingLevel2Channels
+Excitation Wavelength,Excitation Wavelength,ExcitationWavelength,Center/peak of the excitation spectrum (nm),False,,,,ImagingLevel2Channels
+Clone,Clone,Clone,Clone,False,,,,ImagingLevel2Channels
+Metal Isotope Mass,Metal Isotope Mass,MetalIsotopeMass,Element mass number,False,,,,ImagingLevel2Channels
+Target Name,Target Name,TargetName,Short descriptive name (abbreviation) for this target (antigen),False,,,,ImagingLevel2Channels
+Oligo Barcode Upper Strand,Oligo Barcode Upper Strand,OligoBarcodeUpperStrand,Oligo Barcode - Upper Strand,False,,,,ImagingLevel2Channels
+Sub Cycle Number,Sub Cycle Number,SubCycleNumber,Sub cycle number,False,,,,ImagingLevel2Channels
+Metal Isotope Element,Metal Isotope Element,MetalIsotopeElement,Element abbreviation. eg “La” or “Nd”,False,,,,ImagingLevel2Channels
+Prostate Carcinoma Histologic Type,Prostate Carcinoma Histologic Type,ProstateCarcinomaHistologicType,The diagnostic subclassification of an invasive prostate carcinoma.,False,,"['Other', 'Prostatic small cell carcinoma', 'Prostatic adenosquamous carcinoma', 'Prostatic adenocarcinoma (conventional NOS)', 'Undifferentiated carcinoma NOS', 'Acinar prostate adenocarcinoma-signet-ring variant', 'Acinar prostate mucinous adenocarcinoma', 'Acinar prostate adenocarcinoma-sarcomatoid variant', 'Acinar prostate mucinous (colloid) adenocarcinoma', 'Prostatic duct adenocarcinoma', '']",,ProstateCancerTier3
+Location Extent Extraprostatic Extension,Location Extent Extraprostatic Extension,LocationExtentExtraprostaticExtension,Location and extent of extraprostatic extension,False,,"['Left Mid', 'Not Reported', 'unknown', 'Right Anterior', 'Left Posterolateral', 'Right Posterolateral', 'Left Base', 'Right Non-focal (established)', 'Left Lateral', 'Left Anterior', 'Right Focal', 'Left Non-focal (established)', 'Right Lateral', 'Right Base', 'Left Focal', 'Right Posterior', 'Right Apex', 'Right Mid', 'Left Apex', 'Left Posterior', '']",,ProstateCancerTier3
+Prostate Cancer Local Extent,Prostate Cancer Local Extent,ProstateCancerLocalExtent,The response used to categorize the local extent of disease for prostate cancer.,False,,"['Extraprostatic extension', 'unknown', 'Not Reported', 'Organ Confined', '']",,ProstateCancerTier3
+Start Days from Index,Start Days from Index,StartDaysfromIndex,"Number of days from the date of birth (index date) to the date of an event (e.g. exposure to environmental factor, treatment start, etc.). If not applicable please enter 'Not Applicable'",True,,,,ProstateCancerTier3
+Timepoint Label,Timepoint Label,TimepointLabel,"Label to identify the time point at which the clinical data or biospecimen was obtained (e.g. Baseline, End of Treatment, Overall survival, Final). NO PHI/PII INFORMATION IS ALLOWED.",True,,,,ProstateCancerTier3
+HTAN Participant ID,HTAN Participant ID,HTANParticipantID,HTAN ID associated with a patient based on HTAN ID SOP (eg HTANx_yyy ),True,,,,ProstateCancerTier3
+Stop Days from Index,Stop Days from Index,StopDaysfromIndex,"Number of days from the date of birth (index date) to the end date of the event (e.g. exposure to environmental factor, treatment start, etc.). Note: if the event occurs at a single time point, e.g. a diagnosis or a lab test, the values for this column is 'Not Applicable'",False,,,,ProstateCancerTier3
+Seminal Vesicle Invasion,Seminal Vesicle Invasion,SeminalVesicleInvasion,An anatomic position identifying a side of the body where local spread of malignant neoplasm is found to infiltrate tissue in the saclike glandular diverticulum on the ductus deferens in a male.,False,,"['Both sides', 'Not Reported', 'None', 'unknown', 'Right', 'Left', '']",,ProstateCancerTier3
+Prostate Cancer Cytologic Morphologic Subtypes,Prostate Cancer Cytologic Morphologic Subtypes,ProstateCancerCytologicMorphologicSubtypes,Text term that describes various morphological and cytological subtypes in protate tumors.,False,,"['Other', 'prostatic atypical adenomatous hyperplasia (adenosis or AAH)', 'High grade prostatic intraepithelial neoplasia (HGPIN)/ (PIN II & PIN III)', 'Low grade prostatic intraepithelial neoplasia (PIN)/(PIN I)', 'Not Reported', 'prostatic basal cell hyperplasia', 'unknown', 'prostatic clear cell cribiform hyperplasia', '']",,ProstateCancerTier3
+Additonal Findings Uninvolved Prostate,Additonal Findings Uninvolved Prostate,AdditonalFindingsUninvolvedProstate,"Additional findings, uninvolved prostate",False,,"['Other', 'High-grade prostatic intraepithelial neoplasia (PIN)', 'Prostatic Intraductal adenocarcinoma', 'Not Reported', 'unknown', 'Benign prostatic hyperplasia (BPH)', 'Inflammation', '']",,ProstateCancerTier3
+Component,Component,Component,"Category of metadata (e.g. Diagnosis, Biospecimen, scRNA-seq Level 1, etc.); provide the same one for all items/rows.",True,,,,ProstateCancerTier3
+Location Nature Positive Margins,Location Nature Positive Margins,LocationNaturePositiveMargins,Location and nature of positive margins,False,,"['Left Mid', 'Not Reported', 'unknown', 'Right Anterior', 'Left Positive in an area of extraprostatic extension (EPE)', 'Left Posterolateral', 'Vas deferens', 'Apical margin (block DUM)', 'Left Positive in an area of intraprostatic incision (II)', 'Right Posterolateral', 'Left Base', 'Right Positive in an area of extraprostatic extension (EPE)', 'Left Lateral', 'Left Anterior', 'Right Focal', 'Right Lateral', 'Right Base', 'Left Focal', 'Left Extensive', 'Right Posterior', 'Left Positive where it is difficult to distinguish EPE vs II', 'Right Apex', 'Right Positive where it is difficult to distinguish EPE vs II', 'Bladder neck (block PUM)', 'Right Positive in an area of intraprostatic incision (II)', 'Right Mid', 'Right Extensive', 'Left Apex', 'Left Posterior', '']",,ProstateCancerTier3
+Ovarian Cancer Histologic Subtype,Ovarian Cancer Histologic Subtype,OvarianCancerHistologicSubtype,Text term to describe the histological subtype of ovarian cancer in the participant,False,,"['Data not available', 'Sex-cord stromal', 'High-grade endometrioid', 'Clear cell', 'Other', 'Germ cell', 'Low-grade endometrioid', 'Low-grade serous', 'High-grade serous', 'Mucinous', 'unknown', '']",,OvarianCancerTier3
+Start Days from Index,Start Days from Index,StartDaysfromIndex,"Number of days from the date of birth (index date) to the date of an event (e.g. exposure to environmental factor, treatment start, etc.). If not applicable please enter 'Not Applicable'",True,,,,OvarianCancerTier3
+HTAN Participant ID,HTAN Participant ID,HTANParticipantID,HTAN ID associated with a patient based on HTAN ID SOP (eg HTANx_yyy ),True,,,,OvarianCancerTier3
+Stop Days from Index,Stop Days from Index,StopDaysfromIndex,"Number of days from the date of birth (index date) to the end date of the event (e.g. exposure to environmental factor, treatment start, etc.). Note: if the event occurs at a single time point, e.g. a diagnosis or a lab test, the values for this column is 'Not Applicable'",False,,,,OvarianCancerTier3
+Ovarian Cancer Surgical Outcome,Ovarian Cancer Surgical Outcome,OvarianCancerSurgicalOutcome,Text term that describes the kind of surgical treatment administered.,False,,"['Optimal cytoreduction', 'Sub-optimal cytoreduction', 'Data not available', 'R0 resection', 'Other', 'unknown', '']",,OvarianCancerTier3
+Ovarian Cancer Platinum Status,Ovarian Cancer Platinum Status,OvarianCancerPlatinumStatus,Text term to indicate the status of treatment with platinum in participant with ovarian cancer,False,,"['Platinum-sensitive', 'Platinum-resistant', 'Data not available', 'Platinum-refractory', 'unknown', '']",,OvarianCancerTier3
+Timepoint Label,Timepoint Label,TimepointLabel,"Label to identify the time point at which the clinical data or biospecimen was obtained (e.g. Baseline, End of Treatment, Overall survival, Final). NO PHI/PII INFORMATION IS ALLOWED.",True,,,,OvarianCancerTier3
+Component,Component,Component,"Category of metadata (e.g. Diagnosis, Biospecimen, scRNA-seq Level 1, etc.); provide the same one for all items/rows.",True,,,,OvarianCancerTier3
+Component,Component,Component,"Category of metadata (e.g. Diagnosis, Biospecimen, scRNA-seq Level 1, etc.); provide the same one for all items/rows.",True,,,,BulkWESLevel3
+Genomic Reference,Genomic Reference,GenomicReference,Exact version of the human genome reference used in the alignment of reads (e.g. https://www.gencodegenes.org/human/),True,,,,BulkWESLevel3
+Genomic Reference URL,Genomic Reference URL,GenomicReferenceURL,Link to human genome sequence (e.g. ftp://ftp.ebi.ac.uk/pub/databases/gencode/Gencode_human/release_34/GRCh38.primary_assembly.genome.fa.gz) [URL],True,,,,BulkWESLevel3
+Somatic Variants Workflow URL,Somatic Variants Workflow URL,SomaticVariantsWorkflowURL,Generic name for the workflow used to analyze a data set.,True,,,,BulkWESLevel3
+Structural Variant Workflow Type,Structural Variant Workflow Type,StructuralVariantWorkflowType,Generic name for the workflow used to analyze a data set.,True,,"['CNVkit', 'Other Structural Variant Workflow Type', 'CNV', 'BRASS', 'GATK4']",,BulkWESLevel3
+Structural Variant Workflow URL,Structural Variant Workflow URL,StructuralVariantWorkflowURL,Link to workflow document. DockStore.org recommended. URL,True,,,,BulkWESLevel3
+HTAN Parent Data File ID,HTAN Parent Data File ID,HTANParentDataFileID,HTAN Data File Identifier indicating the file(s) from which these files were derived,True,,,,BulkWESLevel3
+Somatic Variants Sample Type,Somatic Variants Sample Type,SomaticVariantsSampleType,Is the sample case or control in somatic variant analysis,True,,"['Control Sample', 'Case Sample']",,BulkWESLevel3
+Somatic Variants Workflow Type,Somatic Variants Workflow Type,SomaticVariantsWorkflowType,Generic name for the workflow used to analyze a data set.,True,,"['MuSE', 'CaVEMan', 'MuTect2', 'Pindel', 'VarScan2', 'Other Somatic Variants Workflow Type', 'SomaticSniper', 'GATK4']",,BulkWESLevel3
+Germline Variants Workflow URL,Germline Variants Workflow URL,GermlineVariantsWorkflowURL,"Link to workflow document, e.g. Github, DockStore.org recommended",True,,,,BulkWESLevel3
+Germline Variants Workflow Type,Germline Variants Workflow Type,GermlineVariantsWorkflowType,Generic name for the workflow used to analyze a data set,True,,"['GATK4', 'Other Germline Variants Workflow Type']",,BulkWESLevel3
+File Format,File Format,fileFormat,"Format of a file (e.g. txt, csv, fastq, bam, etc.)",True,,"['sdf', 'tsv', 'bigwig', 'svg', 'idx', 'svs', 'fig', 'sam', 'json', 'avi', 'sav', 'md', 'dat', 'raw', 'msf', 'am', 'tiff', 'czi', 'hic', 'RData', 'bed narrowPeak', 'pzfx', 'cell am', 'doc', 'chp', 'sra', 'tranches', 'mpg', 'locs', 'wiggle', 'mtx', 'mex', 'fasta', 'tif', 'bam', 'bai', 'OME-TIFF', 'bed gappedPeak', 'gzip', 'bpm', 'm', 'fastq', 'gtf', 'flagstat', 'gct', 'mov', 'bed broadPeak', 'bedgraph', 'csv', 'seg', 'bgzip', 'vcf', 'Python script', 'maf', '7z', 'plink', 'xml', 'hyperlink', 'sif', 'ab1', 'html', 'idat', 'rmd', 'excel', 'mzML', 'dup', 'zip', 'png', 'pdf', 'txt', 'bcf', 'DICOM', 'cloupe', 'jpg', 'powerpoint', 'bed', 'R script', 'recal', 'tagAlign', 'tar', 'sqlite', 'cel', 'Sentrix descriptor file', 'gff3', 'hdf5', 'abf']",,BulkWESLevel3
+Filename,Filename,filename,Name of a file ,True,,,,BulkWESLevel3
+HTAN Data File ID,HTAN Data File ID,HTANDataFileID,Self-identifier for this data file - HTAN ID of this file HTAN ID SOP (eg HTANx_yyy_zzz),True,,,,BulkWESLevel3
+Custom Structural Variant Workflow Type,Custom Structural Variant Workflow Type,CustomStructuralVariantWorkflowType,Specify the name of a custom workflow name,False,True,,"Structural Variant Workflow Type -is- ""Other Structural Variant Workflow Type""",BulkWESLevel3
+Custom Somatic Variants Workflow Type,Custom Somatic Variants Workflow Type,CustomSomaticVariantsWorkflowType,Specify the name of a custom workflow name,False,True,,"Somatic Variants Workflow Type -is- ""Other Somatic Variants Workflow Type""",BulkWESLevel3
+Custom Germline Variants Workflow Type,Custom Germline Variants Workflow Type,CustomGermlineVariantsWorkflowType,Specify the name of a custom alignment workflow,False,True,,"Germline Variants Workflow Type -is- ""Other Germline Variants Workflow Type""",BulkWESLevel3
+scATACseq Read2,scATACseq Read2,ScATACseqRead2,Read 2 content description,True,,"['Sample Index and DNA Insert', 'Sample Index', 'DNA Insert', 'Cell Barcode and DNA Insert', 'Cell Barcode']",,ScATAC-seqLevel1
+Total Number of Passing Nuclei,Total Number of Passing Nuclei,TotalNumberofPassingNuclei,Number of nuclei sequenced,True,,,,ScATAC-seqLevel1
+Component,Component,Component,"Category of metadata (e.g. Diagnosis, Biospecimen, scRNA-seq Level 1, etc.); provide the same one for all items/rows.",True,,,,ScATAC-seqLevel1
+Median Fraction of Reads in Annotated cis DNA Elements,Median Fraction of Reads in Annotated cis DNA Elements,MedianFractionofReadsinAnnotatedcisDNAElements,Median fraction of reads in annotated cis-DNA elements (FRIADE),True,,,,ScATAC-seqLevel1
+Sequencing Platform,Sequencing Platform,SequencingPlatform,A platform is an object aggregate that is the set of instruments and software needed to perform a process [OBI_0000050]. Specific model of the sequencing instrument.,True,,"['NovaSeqS4', 'AB SOLiD 3', 'Illumina Next Seq 550', 'NovaSeq 6000', 'Illumina MiSeq', 'Complete Genomics', 'unknown', 'Illumina Genome Analyzer II', 'Ion Torrent Proton', 'PacBio RS', 'Illumina Next Seq 500', 'Illumina NextSeq', 'Illumina NovaSeq 6000', 'Other', 'Illumina HiSeq 2500', 'Ion Torrent PGM', 'Illumina HiSeq 4000', 'Not Reported', 'Illumina Genome Analyzer IIx', 'AB SOLiD 4 AB SOLiD 2', 'Illumina HiSeq X Ten', 'Illumina Next Seq 2500', 'Illumina HiSeq 2000', 'Illumina HiSeq X Five', 'Ion Torrent S5', '454 GS FLX Titanium']",,ScATAC-seqLevel1
+Median Fraction of Reads in Peaks,Median Fraction of Reads in Peaks,MedianFractionofReadsinPeaks,Median fraction of reads in peaks (FRIP),True,,,,ScATAC-seqLevel1
+Median Percentage of Mitochondrial Reads per Nucleus,Median Percentage of Mitochondrial Reads per Nucleus,MedianPercentageofMitochondrialReadsperNucleus,Contamination from mitochondrial sequences,True,,,,ScATAC-seqLevel1
+scATACseq Read3,scATACseq Read3,ScATACseqRead3,Read 3 content description,False,,"['Sample Index and DNA Insert', 'Sample Index', 'DNA Insert', 'Cell Barcode and DNA Insert', 'Cell Barcode', '']",,ScATAC-seqLevel1
+HTAN Parent Biospecimen ID,HTAN Parent Biospecimen ID,HTANParentBiospecimenID,HTAN Biospecimen Identifier (eg HTANx_yyy_zzz) indicating the biospecimen(s) from which these files were derived; multiple parent biospecimen should be comma-separated,True,,,,ScATAC-seqLevel1
+Transposition Reaction,Transposition Reaction,TranspositionReaction,"Name of the transposase, transposon sequences",True,,"['EZ-Tn5', 'Tn5-059', 'Nextera Tn5', 'In-House', 'Tn5']",,ScATAC-seqLevel1
+Nucleus Identifier,Nucleus Identifier,NucleusIdentifier,Unique nuclei barcode; added at transposition step. Determines which nucleus the reads originated from,True,,['Nuclei Barcode'],,ScATAC-seqLevel1
+File Format,File Format,fileFormat,"Format of a file (e.g. txt, csv, fastq, bam, etc.)",True,,"['vcf', 'dup', 'zip', 'locs', 'hdf5', 'powerpoint', 'svs', 'hic', 'sam', 'Python script', 'ab1', 'cell am', 'wiggle', 'idx', 'maf', 'bed gappedPeak', 'bedgraph', 'gzip', 'gff3', 'pdf', 'mtx', 'OME-TIFF', 'bgzip', 'tsv', 'gct', 'am', 'sif', 'html', 'tranches', 'csv', 'dat', 'md', 'RData', 'json', 'mpg', 'tif', 'seg', 'cel', 'excel', 'mov', 'svg', 'm', 'pzfx', 'fasta', 'xml', 'mex', 'bigwig', 'tagAlign', 'tar', 'plink', 'bed', 'cloupe', 'bai', 'sra', 'mzML', 'rmd', 'msf', 'txt', 'R script', 'czi', 'abf', 'gtf', 'Sentrix descriptor file', '7z', 'raw', 'idat', 'bed narrowPeak', 'fastq', 'bam', 'tiff', 'sdf', 'DICOM', 'avi', 'hyperlink', 'bcf', 'fig', 'bpm', 'sav', 'sqlite', 'chp', 'flagstat', 'bed broadPeak', 'doc', 'jpg', 'png', 'recal']",,ScATAC-seqLevel1
+HTAN Data File ID,HTAN Data File ID,HTANDataFileID,Self-identifier for this data file - HTAN ID of this file HTAN ID SOP (eg HTANx_yyy_zzz),True,,,,ScATAC-seqLevel1
+Dissociation Method,Dissociation Method,DissociationMethod,The tissue dissociation method used for scRNASeq or scATAC-seq assays,True,,"['Not Applicable', 'gentleMACS', 'Enzymatic Digestion', 'Dounce']",,ScATAC-seqLevel1
+Single Cell Isolation Method,Single Cell Isolation Method,SingleCellIsolationMethod,"The method by which cells are isolated into individual reaction containers at a single cell resolution (e.g. wells, micro-droplets)",True,,"['Microfluidics Chip', '10x', 'Plates', 'Droplets', 'FACS', 'Nuclei Isolation']",,ScATAC-seqLevel1
+Median Passing Read Percentage,Median Passing Read Percentage,MedianPassingReadPercentage,Non-PCR duplicate nuclear genomic sequence reads not aligning to unanchored contigs out of total reads assigned to the nucleus barcode,True,,,,ScATAC-seqLevel1
+Library Construction Method,Library Construction Method,LibraryConstructionMethod,Process which results in the creation of a library from fragments of DNA using cloning vectors or oligonucleotides with the role of adaptors [OBI_0000711],True,,"['10xV2', 'Drop-seq', '10xV1.0', 'TruDrop', '10xV1.1', '10xV3', '10xV3.1', 'Smart-SeqV4', 'sci-ATAC-seq', 'CEL-seq2', 'inDropsV2', 'inDropsV3', 'Smart-seq2']",,ScATAC-seqLevel1
+Nucleic Acid Source,Nucleic Acid Source,NucleicAcidSource,The source of the input nucleic molecule,True,,"['Bulk Whole Cell', 'Single Nucleus', 'Bulk Nuclei', 'Single Cell']",,ScATAC-seqLevel1
+Filename,Filename,filename,Name of a file ,True,,,,ScATAC-seqLevel1
+Nuclei Barcode Length,Nuclei Barcode Length,NucleiBarcodeLength,Nuclei Barcode Length,True,,,,ScATAC-seqLevel1
+scATACseq Library Layout,scATACseq Library Layout,ScATACseqLibraryLayout,Sequencing read type,True,,['scATACseq Paired End'],,ScATAC-seqLevel1
+Threshold for Minimum Passing Reads,Threshold for Minimum Passing Reads,ThresholdforMinimumPassingReads,Threshold for calling cells,True,,,,ScATAC-seqLevel1
+Nuclei Barcode Read,Nuclei Barcode Read,NucleiBarcodeRead,Nuclei Barcode Read,True,,,,ScATAC-seqLevel1
+Total Reads,Total Reads,TotalReads,Total number of reads per sample. Integer,False,,,,ScATAC-seqLevel1
+scATACseq Read1,scATACseq Read1,ScATACseqRead1,Read 1 content description,True,,"['Sample Index and DNA Insert', 'Sample Index', 'DNA Insert', 'Cell Barcode and DNA Insert', 'Cell Barcode']",,ScATAC-seqLevel1
+Technical Replicate Group,Technical Replicate Group,TechnicalReplicateGroup,A common term for all files belonging to the same cell or library. Provide a numbering of each library prep batch (can differ from encapsulation and sequencing batch),False,,,,ScATAC-seqLevel1
+Protocol Link,Protocol Link,ProtocolLink,"Protocols.io ID or DOI link to a free/open protocol resource describing in detail the assay protocol (e.g. surface markers used in Smart-seq, dissociation duration,  lot/batch numbers for key reagents such as primers, sequencing reagent kits, etc.) or the protocol by which the sample was obtained or generated.",True,,,,ScATAC-seqLevel1
+Single Nucleus Buffer,Single Nucleus Buffer,SingleNucleusBuffer,Nuclei isolation buffer,True,,"['10x', 'Omni', 'NIB']",,ScATAC-seqLevel1
+Peaks Calling Software,Peaks Calling Software,PeaksCallingSoftware,Generic name of peaks calling tool,False,,,,ScATAC-seqLevel1
+Well Index,Well Index,WellIndex,Indicate if protein expression (EPCAM/CD45) positive/negative data  is available for each cell in CEL-seq2 assays,False,True,"['Yes', 'No', '']","Library Construction Method -is- ""CEL-seq2""",ScATAC-seqLevel1
+Empty Well Barcode,Empty Well Barcode,EmptyWellBarcode,Unique cell barcode assigned to empty cells used as controls in CEL-seq2 assays.,False,True,,"Library Construction Method -is- ""CEL-seq2""",ScATAC-seqLevel1
+HTAN Participant ID,HTAN Participant ID,HTANParticipantID,HTAN ID associated with a patient based on HTAN ID SOP (eg HTANx_yyy ),True,,,,AcuteLymphoblasticLeukemiaTier3
+CNS Leukemia Status,CNS Leukemia Status,CNSLeukemiaStatus,The status of central nervous system leukemia at the time of diagnosis.,False,,"['CNS 3b', 'CNS 1', 'CNS 2c', 'CNS 2a', 'Not evaluated', 'CNS 3', 'CNS 3c', 'CNS 2b', 'unknown', 'CNS 3a', 'CNS 2', '']",,AcuteLymphoblasticLeukemiaTier3
+Stop Days from Index,Stop Days from Index,StopDaysfromIndex,"Number of days from the date of birth (index date) to the end date of the event (e.g. exposure to environmental factor, treatment start, etc.). Note: if the event occurs at a single time point, e.g. a diagnosis or a lab test, the values for this column is 'Not Applicable'",False,,,,AcuteLymphoblasticLeukemiaTier3
+MRD ALL Diagnostic Sensitivity,MRD ALL Diagnostic Sensitivity,MRDALLDiagnosticSensitivity,The assay sensitivity results of a diagnostic assessment of Minimal Residual Disease in patients diagnosed with Acute Lymphoblastic Leukemia.,False,,"['unknown', 'Suboptimal', 'Optimal', 'Indeterminate', '']",,AcuteLymphoblasticLeukemiaTier3
+Start Days from Index,Start Days from Index,StartDaysfromIndex,"Number of days from the date of birth (index date) to the date of an event (e.g. exposure to environmental factor, treatment start, etc.). If not applicable please enter 'Not Applicable'",True,,,,AcuteLymphoblasticLeukemiaTier3
+Specimen Blast Count Percentage Value,Specimen Blast Count Percentage Value,SpecimenBlastCountPercentageValue,"The value, in percent(%) of the medical procedure that involves testing a sample of blood for blast cells, immature (undifferentiated) cells during diagnosis",False,,,,AcuteLymphoblasticLeukemiaTier3
+Component,Component,Component,"Category of metadata (e.g. Diagnosis, Biospecimen, scRNA-seq Level 1, etc.); provide the same one for all items/rows.",True,,,,AcuteLymphoblasticLeukemiaTier3
+Timepoint Label,Timepoint Label,TimepointLabel,"Label to identify the time point at which the clinical data or biospecimen was obtained (e.g. Baseline, End of Treatment, Overall survival, Final). NO PHI/PII INFORMATION IS ALLOWED.",True,,,,AcuteLymphoblasticLeukemiaTier3
+NCI ALL Risk Group,NCI ALL Risk Group,NCIALLRiskGroup,The NCI risk group assigned to a patient at initial diagnosis with Acute Lymphoblastic Leukemia.,False,,"['unknown', 'NCI High Risk', 'NCI Standard Risk', '']",,AcuteLymphoblasticLeukemiaTier3
+INPC Grade,INPC Grade,INPCGrade,"Text term used to describe the classification of neuroblastic differentiation within neuroblastoma tumors, as defined by the International Neuroblastoma Pathology Classification (INPC).",False,,"['Differentiating', 'Not Reported', 'unknown', 'Poorly Differentiated', 'Undifferentiated', '']",,Diagnosis
+Medulloblastoma Molecular Classification,Medulloblastoma Molecular Classification,MedulloblastomaMolecularClassification,The text term used to describe the classification of medulloblastoma tumors based on molecular features.,False,,"['Non-WNT/non-SHH Activated', 'Not Reported', 'Not Determined', 'unknown', 'SHH-Activated', 'WNT-Activated', '']",,Diagnosis
+Percent Tumor Invasion,Percent Tumor Invasion,PercentTumorInvasion,The percentage of tumor cells spread locally in a malignant neoplasm through infiltration or destruction of adjacent tissue.,False,,,,Diagnosis
+Micropapillary Features,Micropapillary Features,MicropapillaryFeatures,The yes/no/unknown indicator used to describe whether micropapillary features were determined to be present.,False,,"['Present', 'Absent', 'Not Reported', 'unknown', '']",,Diagnosis
+Last Known Disease Status,Last Known Disease Status,LastKnownDiseaseStatus,Text term that describes the last known state or condition of an individual's neoplasm.,True,,"['Not Reported', 'unknown tumor status', 'Loco-regional recurrence/progression', 'With tumor', 'Not Allowed To Collect', 'Distant met recurrence/progression', 'Tumor free', 'Not Applicable', 'Biochemical evidence of disease without structural correlate']",,Diagnosis
+Lymphatic Invasion Present,Lymphatic Invasion Present,LymphaticInvasionPresent,"A yes/no indicator to ask if small or thin-walled vessel invasion is present, indicating lymphatic involvement",False,,"['No', 'Yes', 'Not Reported', 'unknown', '']",,Diagnosis
+HTAN Participant ID,HTAN Participant ID,HTANParticipantID,HTAN ID associated with a patient based on HTAN ID SOP (eg HTANx_yyy ),True,,,,Diagnosis
+Greatest Tumor Dimension,Greatest Tumor Dimension,GreatestTumorDimension,Numeric value that represents the measurement of the widest portion of the tumor in centimeters.,False,,,,Diagnosis
+Cog Rhabdomyosarcoma Risk Group,Cog Rhabdomyosarcoma Risk Group,CogRhabdomyosarcomaRiskGroup,"Text term used to describe the classification of rhabdomyosarcoma, as defined by the Children's Oncology Group (COG).",False,,"['Low Risk', 'Not Reported', 'High Risk', 'unknown', 'Intermediate Risk', '']",,Diagnosis
+Lymph Nodes Positive,Lymph Nodes Positive,LymphNodesPositive,The number of lymph nodes involved with disease as determined by pathologic examination.,False,,,,Diagnosis
+Best Overall Response,Best Overall Response,BestOverallResponse,The best improvement achieved throughout the entire course of protocol treatment.,False,,"['PB-Palliative Benefit', 'RD-Responsive Disease', 'PSR-Pseudoresponse', 'RPD-Radiographic Progressive Disease', 'TE-Too Early', 'VGPR-Very Good Partial Response', 'CPD-Clinical Progression', 'MR-Minimal/Marginal Response', 'CRU-Complete Response Unconfirmed', 'RP-Response', 'NPB-No Palliative Benefit', 'Non-CR/Non-PD-Non-CR/Non-PD', 'PR-Partial Response', 'sCR-Stringent Complete Response', 'DU-Disease Unchanged', 'AJ-Adjuvant Therapy', 'SPD-Surgical Progression', 'CR-Complete Response', 'PD-Progressive Disease', 'IMR-Immunoresponse', 'PPD-Pseudoprogression', 'IPD-Immunoprogression', 'NR-No Response', 'PA-Palliative Therapy', 'SD-Stable Disease', 'MX-Mixed Response', '']",,Diagnosis
+Supratentorial Localization,Supratentorial Localization,SupratentorialLocalization,Text term to specify the location of the supratentorial tumor.,False,,"['Not Reported', 'Cerebral Cortex', 'unknown', 'Spinal Cord', 'White Matter', 'Deep Gray', '']",,Diagnosis
+Secondary Gleason Grade,Secondary Gleason Grade,SecondaryGleasonGrade,"The text term used to describe the secondary Gleason score, which describes the pattern of cells making up the second largest area of the tumor. The primary and secondary Gleason pattern grades are combined to determine the patient's Gleason grade group, which is used to determine the aggresiveness of prostate cancer. Note that this grade describes the entire prostatectomy specimen and is not specific to the sample used for sequencing.",False,,"['Pattern 5', 'Pattern 4', 'Pattern 1', 'Pattern 2', 'Pattern 3', '']",,Diagnosis
+Gleason Grade Tertiary,Gleason Grade Tertiary,GleasonGradeTertiary,The text term used to describe the tertiary pattern as described by the Gleason Grading System.,False,,"['Pattern 5', 'Pattern 4', '']",,Diagnosis
+INRG Stage,INRG Stage,INRGStage,"The text term used to describe the staging classification of neuroblastic tumors, as defined by the International Neuroblastoma Risk Group (INRG).",False,,"['Not Reported', 'L2', 'unknown', 'm', 'Ms', 'L1', '']",,Diagnosis
+Tumor Grade,Tumor Grade,TumorGrade,"Numeric value to express the degree of abnormality of cancer cells, a measure of differentiation and aggressiveness.",True,,"['G1', 'Not Reported', 'G2', 'unknown', 'G3', 'High Grade', 'GX', 'Low Grade', 'Not Applicable', 'Intermediate Grade', 'G4', 'GB']",,Diagnosis
+INSS Stage,INSS Stage,INSSStage,"Text term used to describe the staging classification of neuroblastic tumors, as defined by the International Neuroblastoma Staging System (INSS).",False,,"['Not Reported', 'Stage 2A', 'unknown', 'Stage 4S', 'Stage 2B', 'Stage 1', 'Stage 4', 'Stage 3', '']",,Diagnosis
+Prior Malignancy,Prior Malignancy,PriorMalignancy,The yes/no/unknown indicator used to describe the patient's history of prior cancer diagnosis.,False,,"['Not Reported', 'unknown', 'Not Allowed To Collect', 'No', 'Yes', '']",,Diagnosis
+Days to Last Follow up,Days to Last Follow up,DaystoLastFollowup,"Time interval from the date of last follow up to the date of initial pathologic diagnosis, represented as a calculated number of days.",True,,,,Diagnosis
+Pregnant at Diagnosis,Pregnant at Diagnosis,PregnantatDiagnosis,The text term used to indicate whether the patient was pregnant at the time they were diagnosed.,False,,"['No', 'Yes', 'Not Reported', 'unknown', '']",,Diagnosis
+Tumor Confined to Organ of Origin,Tumor Confined to Organ of Origin,TumorConfinedtoOrganofOrigin,The yes/no/unknown indicator used to describe whether the tumor is confined to the organ where it originated and did not spread to a proximal or distant location within the body.,False,,"['No', 'Yes', 'Not Reported', 'unknown', '']",,Diagnosis
+AJCC Clinical M,AJCC Clinical M,AJCCClinicalM,"Extent of the distant metastasis for the cancer based on evidence obtained from clinical
+ assessment parameters determined prior to treatment.",False,,"['Not Reported', 'MX', 'unknown', 'M1c', 'M1a', 'M1b', 'M1', 'M0', 'cM0 (i+)', '']",,Diagnosis
+AJCC Clinical Stage,AJCC Clinical Stage,AJCCClinicalStage,"Stage group determined from clinical information on the tumor (T), regional node (N) and
+ metastases (M) and by grouping cases with similar prognosis for cancer.",False,,"['Stage IIB', 'Not Reported', 'Stage IB2', 'Stage IB1', 'Stage II', 'Stage IIA1', 'Stage IA2', 'Stage IA', 'Stage I', 'Stage IVB', 'Stage IIC', 'Stage IC', 'Stage 0a', 'unknown', 'Stage IA1', 'Stage IIIB', 'Stage X', 'Stage III', 'Stage IIA', 'Stage 0', 'Stage IVA', 'Stage Tis', 'Stage IIC1', 'Stage IIIC', 'Stage 0is', 'Stage IVC', 'Stage IIIC1', 'Stage IB', 'Stage IIA2', 'Stage IIIC2', 'Stage IIIA', 'Stage IS', 'Stage IV', '']",,Diagnosis
+WHO NTE Grade,WHO NTE Grade,WHONTEGrade,WHO NTE Grade,False,,"['G1', 'Not Reported', 'G2', 'unknown', 'G3', 'GX', '']",,Diagnosis
+Margin Distance,Margin Distance,MarginDistance,Numeric value (in centimeters) that represents the distance between the tumor and the surgical margin.,False,,,,Diagnosis
+Progression or Recurrence,Progression or Recurrence,ProgressionorRecurrence,Yes/No/unknown indicator to identify whether a patient has had a new tumor event after initial treatment.,True,,"['No', 'unknown', 'Not Reported', 'Yes - Progression or Recurrence']",,Diagnosis
+Tumor Largest Dimension Diameter,Tumor Largest Dimension Diameter,TumorLargestDimensionDiameter,"Numeric value used to describe the maximum diameter or dimension of the primary tumor, measured in centimeters.",False,,,,Diagnosis
+INPC Histologic Group,INPC Histologic Group,INPCHistologicGroup,"The text term used to describe the classification of neuroblastomas distinguishing between favorable and unfavorable histologic groups. The histologic score, defined by the International Neuroblastoma Pathology Classification (INPC), is based on age, mitosis-karyorrhexis index (MKI), stromal content and degree of tumor cell differentiation.",False,,"['Favorable', 'unknown', 'Not Reported', 'Unfavorable', '']",,Diagnosis
+Ovarian Surface Involvement,Ovarian Surface Involvement,OvarianSurfaceInvolvement,The text term that describes whether the surface tissue (outer boundary) of the ovary shows evidence of involvement or presence of cancer.,False,,"['Not Reported', 'unknown', 'Absent', 'Present', 'Indeterminate', '']",,Diagnosis
+Peritoneal Fluid Cytological Status,Peritoneal Fluid Cytological Status,PeritonealFluidCytologicalStatus,The text term used to describe the malignant status of the peritoneal fluid determined by cytologic testing.,False,,"['Atypical', 'Malignant', 'Not Reported', 'unknown', 'Unsatisfactory', 'Non-Malignant', '']",,Diagnosis
+AJCC Staging System Edition,AJCC Staging System Edition,AJCCStagingSystemEdition,"The text term used to describe the version or edition of the American Joint Committee on Cancer
+ Staging Handbooks, a publication by the group formed for the purpose of developing a system of
+ staging for cancer that is acceptable to the American medical profession and is compatible with
+ other accepted classifications.",False,,"['Not Reported', '2nd', '4th', '3rd', '8th', 'unknown', '7th', '5th', '1st', '6th', '']",,Diagnosis
+Mitotic Count,Mitotic Count,MitoticCount,"The number of mitoses identified under the microscope in tumors. The method of counting varies, according to the specific tumor examined. Usually, the mitotic count is determined based on the number of mitoses per high power field (40X) or 10 high power fields.",False,,,,Diagnosis
+Cog Neuroblastoma Risk Group,Cog Neuroblastoma Risk Group,CogNeuroblastomaRiskGroup,Text term that represents the categorization of patients on the basis of prognostic factors per a system developed by Children's Oncology Group (COG). Risk level is used to assign treatment intensity.,False,,"['Low Risk', 'Not Reported', 'High Risk', 'unknown', 'Intermediate Risk', '']",,Diagnosis
+Gleason Patterns Percent,Gleason Patterns Percent,GleasonPatternsPercent,"Numeric value that represents the percentage of Patterns 4 and 5, which is used when the Gleason score is greater than 7 to predict prognosis.",False,,,,Diagnosis
+Classification of Tumor,Classification of Tumor,ClassificationofTumor,Text that describes the kind of disease present in the tumor specimen as related to a specific timepoint.,False,,"['Not Reported', 'unknown', 'Primary', 'Other', 'Not Allowed To Collect', 'Recurrence', 'Metastasis', '']",,Diagnosis
+Lymph Node Involved Site,Lymph Node Involved Site,LymphNodeInvolvedSite,The text term used to describe the anatomic site of lymph node involvement.,False,,"['Not Reported', 'None', 'Cervical', 'Hilar', 'Femoral', 'Paraaortic', 'Occipital', 'unknown', 'Popliteal', 'Parotid', 'Iliac-external', 'Splenic', 'Mediastinal', 'Supraclavicular', 'Retroperitoneal', 'Inguinal', 'Epitrochlear', 'Mesenteric', 'NOS', 'Submandibular', 'Iliac', 'Iliac-common', 'Axillary', '']",,Diagnosis
+Age at Diagnosis,Age at Diagnosis,AgeatDiagnosis,Age at the time of diagnosis expressed in number of days since birth.,True,,,,Diagnosis
+Method of Diagnosis,Method of Diagnosis,MethodofDiagnosis,Text term used to describe the method used to confirm the patients malignant diagnosis.,False,,"['Excisional Biopsy', 'Not Reported', 'Pathologic Review', 'Diagnostic Imaging', 'Enucleation', 'Debulking', 'Ultrasound Guided Biopsy', 'Biopsy', 'Imaging', 'Laparoscopy', 'Cytology', 'Laparotomy', 'unknown', 'Incisional Biopsy', 'Pap Smear', 'Cystoscopy', 'Surgical Resection', 'Fine Needle Aspiration', 'Blood Draw', 'Autopsy', 'Physical Exam', 'Dilation and Curettage Procedure', 'Thoracentesis', 'Core Biopsy', 'Bone Marrow Aspirate', 'Other', '']",,Diagnosis
+Days to Last Known Disease Status,Days to Last Known Disease Status,DaystoLastKnownDiseaseStatus,"Time interval from the date of last follow up to the date of initial pathologic diagnosis, represented as a calculated number of days.",True,,,,Diagnosis
+AJCC Pathologic M,AJCC Pathologic M,AJCCPathologicM,"Code to represent the defined absence or presence of distant spread or metastases (M) to
+ locations via vascular channels or lymphatics beyond the regional lymph nodes, using
+ criteria established by the American Joint Committee on Cancer (AJCC).",False,,"['Not Reported', 'MX', 'unknown', 'M1c', 'M1a', 'M1b', 'M1', 'M0', 'cM0 (i+)', '']",,Diagnosis
+Vascular Invasion Type,Vascular Invasion Type,VascularInvasionType,Text term that represents the type of vascular tumor invasion.,False,,"['Not Reported', 'unknown', 'Micro', 'Macro', 'No Vascular Invasion', 'Extramural', 'Intramural', '']",,Diagnosis
+Breslow Thickness,Breslow Thickness,BreslowThickness,"The number that describes the distance, in millimeters, between the upper layer of the epidermis and the deepest point of tumor penetration.",False,,,,Diagnosis
+Lymph Nodes Tested,Lymph Nodes Tested,LymphNodesTested,The number of lymph nodes tested to determine whether lymph nodes were involved with disease as determined by a pathologic examination.,False,,,,Diagnosis
+Tissue or Organ of Origin,Tissue or Organ of Origin,TissueorOrganofOrigin,"The text term used to describe the anatomic site of origin, of the patient's malignant disease, as described by the World Health Organization's (WHO) International Classification of Diseases for Oncology (ICD-O).",True,,"['Lymph nodes of multiple regions', 'Overlapping lesion of lung', 'Peripheral nerves and autonomic nervous system of abdomen', 'Placenta', 'Thymus', 'Kidney NOS', 'Lesser curvature of stomach NOS', 'Ascending colon', 'Vertebral column', 'Axillary tail of breast', 'Cortex of adrenal gland', 'Brain NOS', 'Cheek mucosa', 'Overlapping lesion of floor of mouth', 'Overlapping lesion of accessory sinuses', 'Intra-abdominal lymph nodes', 'Connective subcutaneous and other soft tissues of pelvis', 'External upper lip', 'Esophagus NOS', 'Vestibule of mouth', 'Waldeyer ring', 'Lymph nodes of head face and neck', 'Adrenal gland NOS', 'Short bones of upper limb and associated joints', 'Meninges NOS', 'Short bones of lower limb and associated joints', 'Other ill-defined sites', 'Upper lobe lung', 'Ventricle NOS', 'Head of pancreas', 'Orbit NOS', 'Pituitary gland', 'Frontal sinus', 'Dorsal surface of tongue NOS', 'Spleen', 'Skin of upper limb and shoulder', 'Supraglottis', 'Anal canal', 'Nipple', 'Ureteric orifice', 'Overlapping lesion of endocrine glands and related structures', 'Upper-inner quadrant of breast', 'Overlapping lesion of tonsil', 'Cardia NOS', 'Ciliary body', 'Bone marrow', 'Extrahepatic bile duct', 'Ethmoid sinus', 'Oropharynx NOS', 'Base of tongue NOS', 'Lacrimal gland', 'Pharynx NOS', 'Submandibular gland', 'Parotid gland', 'Gastrointestinal tract NOS', 'Lymph nodes of inguinal region or leg', 'Broad ligament', 'Medulla of adrenal gland', 'Body of stomach', 'Paraurethral gland', 'Scrotum NOS', 'Hypopharynx NOS', 'Intrathoracic lymph nodes', 'Pylorus', 'Isthmus uteri', 'Upper limb NOS', 'Sigmoid colon', 'Major salivary gland NOS', 'Mucosa of lip NOS', 'Main bronchus', 'Uterus NOS', 'Lower-inner quadrant of breast', 'Other specified parts of pancreas', 'Fundus of stomach', 'Ventral surface of tongue NOS', 'Overlapping lesion of vulva', 'Vallecula', 'Anterior wall of nasopharynx', 'Posterior wall of oropharynx', 'Sublingual gland', 'Fundus uteri', 'Anterior wall of bladder', 'Spinal cord', 'Cerebrum', 'Superior wall of nasopharynx', 'Descended testis', 'Rectum NOS', 'Peripheral nerves and autonomic nervous system of trunk NOS', 'External lower lip', 'Mucosa of lower lip', 'unknown', 'Connective subcutaneous and other soft tissues of lower limb and hip', 'Border of tongue', 'Cervix uteri', 'Connective subcutaneous and other soft tissues NOS', 'Tonsil NOS', 'Temporal lobe', 'Trachea', 'Lower gum', 'Head face or neck NOS', 'Glottis', 'Overlapping lesion of palate', 'Middle lobe lung', 'Other specified parts of female genital organs', 'Not Reported', 'Thyroid gland', 'Vulva NOS', 'Lymph nodes of axilla or arm', 'Overlapping lesion of small intestine', 'Ill-defined sites within respiratory system', 'Connective subcutaneous and other soft tissues of trunk NOS', 'Overlapping lesion of urinary organs', 'Thorax NOS', 'Ampulla of Vater', 'Lymph node NOS', 'Corpus uteri', 'Biliary tract NOS', 'Acoustic nerve', 'Reticuloendothelial system NOS', 'Soft palate NOS', 'Conjunctiva', 'Cervical esophagus', 'Myometrium', 'Ovary', 'Overlapping lesion of cervix uteri', 'Epididymis', 'Exocervix', 'Overlapping lesion of respiratory system and intrathoracic organs', 'Cloacogenic zone', 'Overlapping lesion of esophagus', 'Dome of bladder', 'Spermatic cord', 'Thoracic esophagus', 'Vagina NOS', 'Blood', 'Female genital tract NOS', 'Other specified parts of male genital organs', 'Overlapping lesion of hypopharynx', 'Overlapping lesion of nasopharynx', 'Long bones of upper limb scapula and associated joints', 'Cranial nerve NOS', 'Glans penis', 'Occipital lobe', 'Bladder NOS', 'Aortic body and other paraganglia', 'Appendix', 'Subglottis', 'Stomach NOS', 'Mandible', 'Testis NOS', 'Overlapping lesion of bladder', 'Urachus', 'Bladder neck', 'Overlapping lesion of major salivary glands', 'Skin of lip NOS', 'Lateral floor of mouth', 'Overlapping lesion of lip', 'Hard palate', 'Retroperitoneum', 'Central portion of breast', 'Overlapping lesion of digestive system', 'Overlapping lesion of penis', 'Spinal meninges', 'Connective subcutaneous and other soft tissues of head face and neck', 'Overlapping lesion of lip oral cavity and pharynx', 'Body of pancreas', 'Pleura NOS', 'Pancreatic duct', 'Overlapping lesion of corpus uteri', 'Eyelid', 'Splenic flexure of colon', 'Mediastinum NOS', 'Labium majus', 'Body of penis', 'Transverse colon', 'Overlapping lesion of pancreas', 'Rib sternum clavicle and associated joints', 'Trigone of bladder', 'External ear', 'Laryngeal cartilage', 'Mouth NOS', 'Abdomen NOS', 'Nasopharynx NOS', 'Craniopharyngeal duct', 'Peripheral nerves and autonomic nervous system of thorax', 'Tongue NOS', 'Hypopharyngeal aspect of aryepiglottic fold', 'Parietal lobe', 'Bone of limb NOS', 'Peritoneum NOS', 'Abdominal esophagus', 'Palate NOS', 'Round ligament', 'Prepuce', 'Islets of Langerhans', 'Gastric antrum', 'Peripheral nerves and autonomic nervous system of pelvis', 'Overlapping lesion of tongue', 'Skin of trunk', 'Fallopian tube', 'Cecum', 'Pancreas NOS', 'Middle ear', 'Overlapping lesion of heart mediastinum and pleura', 'Pelvic lymph nodes', 'Connective subcutaneous and other soft tissues of thorax', 'Lip NOS', 'Bone NOS', 'Cerebellum NOS', 'Connective subcutaneous and other soft tissues of upper limb and shoulder', 'Lower third of esophagus', 'Hepatic flexure of colon', 'Autonomic nervous system NOS', 'Tonsillar pillar', 'Anterior surface of epiglottis', 'Lateral wall of bladder', 'Jejunum', 'Retina', 'unknown primary site', 'Paraspinal', 'Skin of lower limb and hip', 'Lingual tonsil', 'Breast NOS', 'Skin of scalp and neck', 'Overlapping lesion of retroperitoneum and peritoneum', 'Overlapping lesion of eye and adnexa', 'Parametrium', 'Upper respiratory tract NOS', 'Bones of skull and face and associated joints', 'Labium minus', 'Prostate gland', 'Connective subcutaneous and other soft tissues of abdomen', 'Overlapping lesion of other and unspecified parts of mouth', 'External lip NOS', 'Peripheral nerves and autonomic nervous system of lower limb and hip', 'Retromolar area', 'Middle third of esophagus', 'Ureter', 'Frontal lobe', 'Cerebral meninges', 'Liver', 'Colon NOS', 'Descending colon', 'Overlapping lesion of female genital organs', 'Lateral wall of oropharynx', 'Overlapping lesion of ill-defined sites', 'Choroid', 'Lower-outer quadrant of breast', 'Upper third of esophagus', 'Anus NOS', 'Pelvic bones sacrum coccyx and associated joints', 'Overlapping lesion of brain and central nervous system', 'Anterior floor of mouth', 'Nervous system NOS', 'Eye NOS', 'Overlapping lesion of breast', 'Intestinal tract NOS', 'Carotid body', 'Heart', 'Gum NOS', 'Larynx NOS', 'Uterine adnexa', 'Upper gum', 'Duodenum', 'Accessory sinus NOS', 'Anterior 2/3 of tongue NOS', 'Rectosigmoid junction', 'Anterior mediastinum', 'Peripheral nerves and autonomic nervous system of head face and neck', 'Penis NOS', 'Endometrium', 'Commissure of lip', 'Overlapping lesion of larynx', 'Lower limb NOS', 'Overlapping lesion of colon', 'Nasal cavity', 'Overlapping lesion of brain', 'Overlapping lesion of biliary tract', 'Pineal gland', 'Gallbladder', 'Overlapping lesion of male genital organs', 'Uvula', 'Posterior mediastinum', 'Specified parts of peritoneum', 'Overlapping lesion of skin', 'Mucosa of upper lip', 'Undescended testis', 'Overlapping lesions of oropharynx', 'Clitoris', 'Urinary system NOS', 'Overlapping lesion of bones joints and articular cartilage of limbs', 'Brain stem', 'Posterior wall of nasopharynx', 'Hematopoietic system NOS', 'Endocervix', 'Small intestine NOS', 'Pelvis NOS', 'Overlapping lesion of connective subcutaneous and other soft tissues', 'Renal pelvis', 'Meckel diverticulum', 'Peripheral nerves and autonomic nervous system of upper limb and shoulder', 'Lateral wall of nasopharynx', 'Branchial cleft', 'Pyriform sinus', 'Postcricoid region', 'Ileum', 'Sphenoid sinus', 'Posterior wall of bladder', 'Overlapping lesion of bones joints and articular cartilage', 'Greater curvature of stomach NOS', 'Parathyroid gland', 'Skin of other and unspecified parts of face', 'Floor of mouth NOS', 'Optic nerve', 'Upper-outer quadrant of breast', 'Posterior wall of hypopharynx', 'Endocrine gland NOS', 'Long bones of lower limb and associated joints', 'Maxillary sinus', 'Male genital organs NOS', 'Skin NOS', 'Overlapping lesion of peripheral nerves and autonomic nervous system', 'Tonsillar fossa', 'Overlapping lesion of stomach', 'Lower lobe lung', 'Intrahepatic bile duct', 'Cornea NOS', 'Olfactory nerve', 'Lung NOS', 'Urethra', 'Cauda equina', 'Tail of pancreas', 'Overlapping lesion of rectum anus and anal canal']",,Diagnosis
+Year of Diagnosis,Year of Diagnosis,YearofDiagnosis,Numeric value to represent the year of an individual's initial pathologic diagnosis of cancer.,False,,,,Diagnosis
+AJCC Clinical T,AJCC Clinical T,AJCCClinicalT,"Extent of the primary cancer based on evidence obtained from clinical assessment parameters
+ determined prior to treatment.",False,,"['Not Reported', 'T4c', 'T4e', 'T3', 'T2a2', 'T1a', 'T2', 'T2a1', 'Tis (LCIS)', 'T1a2', 'unknown', 'T2b', 'T3a', 'T1b1', 'T1a1', 'T2d', 'T3d', 'T1', 'T2a', 'T3c', 'T4a', 'T3b', 'T4b', 'TX', 'T4d', 'T1b', 'T2c', 'T4', 'T1c', ""Tis (Paget's)"", 'Ta', 'T1mi', 'Tis', 'T0', 'T1b2', 'Tis (DCIS)', '']",,Diagnosis
+AJCC Clinical N,AJCC Clinical N,AJCCClinicalN,"Extent of the regional lymph node involvement for the cancer based on evidence obtained from
+ clinical assessment parameters determined prior to treatment.",False,,"['N0 (i-)', 'Not Reported', 'N1b', 'N1bIV', 'N1a', 'unknown', 'N3', 'N1bII', 'N3b', 'N1bI', 'N1bIII', 'N2a', 'N3a', 'N2c', 'N0 (mol-)', 'N2', 'N0 (mol+)', 'N1', 'N0', 'N1mi', 'N4', 'N1c', 'N0 (i+)', 'N3c', 'NX', 'N2b', '']",,Diagnosis
+IRS Stage,IRS Stage,IRSStage,"The text term used to describe the classification of rhabdomyosarcoma tumors, as defined by the Intergroup Rhabdomyosarcoma Study (IRS).",False,,"['Not Reported', '4', 'unknown', '3', '1', '2', '']",,Diagnosis
+ISS Stage,ISS Stage,ISSStage,The multiple myeloma disease stage at diagnosis.,False,,"['Not Reported', 'I', 'II', 'unknown', 'III', '']",,Diagnosis
+Tumor Focality,Tumor Focality,TumorFocality,The text term used to describe whether the patient's disease originated in a single location or multiple locations.,False,,"['unknown', 'Not Reported', 'Multifocal', 'Unifocal', '']",,Diagnosis
+Site of Resection or Biopsy,Site of Resection or Biopsy,SiteofResectionorBiopsy,"The text term used to describe the anatomic site of origin, of the patient's malignant disease, as described by the World Health Organization's (WHO) International Classification of Diseases for Oncology (ICD-O).",True,,"['Lymph nodes of multiple regions', 'Overlapping lesion of lung', 'Peripheral nerves and autonomic nervous system of abdomen', 'Placenta', 'Thymus', 'Kidney NOS', 'Lesser curvature of stomach NOS', 'Ascending colon', 'Vertebral column', 'Axillary tail of breast', 'Cortex of adrenal gland', 'Brain NOS', 'Cheek mucosa', 'Overlapping lesion of floor of mouth', 'Overlapping lesion of accessory sinuses', 'Intra-abdominal lymph nodes', 'Connective subcutaneous and other soft tissues of pelvis', 'External upper lip', 'Esophagus NOS', 'Vestibule of mouth', 'Waldeyer ring', 'Lymph nodes of head face and neck', 'Adrenal gland NOS', 'Short bones of upper limb and associated joints', 'Meninges NOS', 'Short bones of lower limb and associated joints', 'Other ill-defined sites', 'Upper lobe lung', 'Ventricle NOS', 'Head of pancreas', 'Orbit NOS', 'Pituitary gland', 'Frontal sinus', 'Dorsal surface of tongue NOS', 'Spleen', 'Skin of upper limb and shoulder', 'Supraglottis', 'Anal canal', 'Nipple', 'Ureteric orifice', 'Overlapping lesion of endocrine glands and related structures', 'Upper-inner quadrant of breast', 'Overlapping lesion of tonsil', 'Cardia NOS', 'Ciliary body', 'Bone marrow', 'Extrahepatic bile duct', 'Ethmoid sinus', 'Oropharynx NOS', 'Base of tongue NOS', 'Lacrimal gland', 'Pharynx NOS', 'Submandibular gland', 'Parotid gland', 'Gastrointestinal tract NOS', 'Lymph nodes of inguinal region or leg', 'Broad ligament', 'Medulla of adrenal gland', 'Body of stomach', 'Paraurethral gland', 'Scrotum NOS', 'Hypopharynx NOS', 'Intrathoracic lymph nodes', 'Pylorus', 'Isthmus uteri', 'Upper limb NOS', 'Sigmoid colon', 'Major salivary gland NOS', 'Mucosa of lip NOS', 'Main bronchus', 'Uterus NOS', 'Lower-inner quadrant of breast', 'Other specified parts of pancreas', 'Fundus of stomach', 'Ventral surface of tongue NOS', 'Overlapping lesion of vulva', 'Vallecula', 'Anterior wall of nasopharynx', 'Posterior wall of oropharynx', 'Sublingual gland', 'Fundus uteri', 'Anterior wall of bladder', 'Spinal cord', 'Cerebrum', 'Superior wall of nasopharynx', 'Descended testis', 'Rectum NOS', 'Peripheral nerves and autonomic nervous system of trunk NOS', 'External lower lip', 'Mucosa of lower lip', 'unknown', 'Connective subcutaneous and other soft tissues of lower limb and hip', 'Border of tongue', 'Cervix uteri', 'Connective subcutaneous and other soft tissues NOS', 'Tonsil NOS', 'Temporal lobe', 'Trachea', 'Lower gum', 'Head face or neck NOS', 'Glottis', 'Overlapping lesion of palate', 'Middle lobe lung', 'Other specified parts of female genital organs', 'Not Reported', 'Thyroid gland', 'Vulva NOS', 'Lymph nodes of axilla or arm', 'Overlapping lesion of small intestine', 'Ill-defined sites within respiratory system', 'Connective subcutaneous and other soft tissues of trunk NOS', 'Overlapping lesion of urinary organs', 'Thorax NOS', 'Ampulla of Vater', 'Lymph node NOS', 'Corpus uteri', 'Biliary tract NOS', 'Acoustic nerve', 'Reticuloendothelial system NOS', 'Soft palate NOS', 'Conjunctiva', 'Cervical esophagus', 'Myometrium', 'Ovary', 'Overlapping lesion of cervix uteri', 'Epididymis', 'Exocervix', 'Overlapping lesion of respiratory system and intrathoracic organs', 'Cloacogenic zone', 'Overlapping lesion of esophagus', 'Dome of bladder', 'Spermatic cord', 'Thoracic esophagus', 'Vagina NOS', 'Blood', 'Female genital tract NOS', 'Other specified parts of male genital organs', 'Overlapping lesion of hypopharynx', 'Overlapping lesion of nasopharynx', 'Long bones of upper limb scapula and associated joints', 'Cranial nerve NOS', 'Glans penis', 'Occipital lobe', 'Bladder NOS', 'Aortic body and other paraganglia', 'Appendix', 'Subglottis', 'Stomach NOS', 'Mandible', 'Testis NOS', 'Overlapping lesion of bladder', 'Urachus', 'Bladder neck', 'Overlapping lesion of major salivary glands', 'Skin of lip NOS', 'Lateral floor of mouth', 'Overlapping lesion of lip', 'Hard palate', 'Retroperitoneum', 'Central portion of breast', 'Overlapping lesion of digestive system', 'Overlapping lesion of penis', 'Spinal meninges', 'Connective subcutaneous and other soft tissues of head face and neck', 'Overlapping lesion of lip oral cavity and pharynx', 'Body of pancreas', 'Pleura NOS', 'Pancreatic duct', 'Overlapping lesion of corpus uteri', 'Eyelid', 'Splenic flexure of colon', 'Mediastinum NOS', 'Labium majus', 'Body of penis', 'Transverse colon', 'Overlapping lesion of pancreas', 'Rib sternum clavicle and associated joints', 'Trigone of bladder', 'External ear', 'Laryngeal cartilage', 'Mouth NOS', 'Abdomen NOS', 'Nasopharynx NOS', 'Craniopharyngeal duct', 'Peripheral nerves and autonomic nervous system of thorax', 'Tongue NOS', 'Hypopharyngeal aspect of aryepiglottic fold', 'Parietal lobe', 'Bone of limb NOS', 'Peritoneum NOS', 'Abdominal esophagus', 'Palate NOS', 'Round ligament', 'Prepuce', 'Islets of Langerhans', 'Gastric antrum', 'Peripheral nerves and autonomic nervous system of pelvis', 'Overlapping lesion of tongue', 'Skin of trunk', 'Fallopian tube', 'Cecum', 'Pancreas NOS', 'Middle ear', 'Overlapping lesion of heart mediastinum and pleura', 'Pelvic lymph nodes', 'Connective subcutaneous and other soft tissues of thorax', 'Lip NOS', 'Bone NOS', 'Cerebellum NOS', 'Connective subcutaneous and other soft tissues of upper limb and shoulder', 'Lower third of esophagus', 'Hepatic flexure of colon', 'Autonomic nervous system NOS', 'Tonsillar pillar', 'Anterior surface of epiglottis', 'Lateral wall of bladder', 'Jejunum', 'Retina', 'unknown primary site', 'Paraspinal', 'Skin of lower limb and hip', 'Lingual tonsil', 'Breast NOS', 'Skin of scalp and neck', 'Overlapping lesion of retroperitoneum and peritoneum', 'Overlapping lesion of eye and adnexa', 'Parametrium', 'Upper respiratory tract NOS', 'Bones of skull and face and associated joints', 'Labium minus', 'Prostate gland', 'Connective subcutaneous and other soft tissues of abdomen', 'Overlapping lesion of other and unspecified parts of mouth', 'External lip NOS', 'Peripheral nerves and autonomic nervous system of lower limb and hip', 'Retromolar area', 'Middle third of esophagus', 'Ureter', 'Frontal lobe', 'Cerebral meninges', 'Liver', 'Colon NOS', 'Descending colon', 'Overlapping lesion of female genital organs', 'Lateral wall of oropharynx', 'Overlapping lesion of ill-defined sites', 'Choroid', 'Lower-outer quadrant of breast', 'Upper third of esophagus', 'Anus NOS', 'Pelvic bones sacrum coccyx and associated joints', 'Overlapping lesion of brain and central nervous system', 'Anterior floor of mouth', 'Nervous system NOS', 'Eye NOS', 'Overlapping lesion of breast', 'Intestinal tract NOS', 'Carotid body', 'Heart', 'Gum NOS', 'Larynx NOS', 'Uterine adnexa', 'Upper gum', 'Duodenum', 'Accessory sinus NOS', 'Anterior 2/3 of tongue NOS', 'Rectosigmoid junction', 'Anterior mediastinum', 'Peripheral nerves and autonomic nervous system of head face and neck', 'Penis NOS', 'Endometrium', 'Commissure of lip', 'Overlapping lesion of larynx', 'Lower limb NOS', 'Overlapping lesion of colon', 'Nasal cavity', 'Overlapping lesion of brain', 'Overlapping lesion of biliary tract', 'Pineal gland', 'Gallbladder', 'Overlapping lesion of male genital organs', 'Uvula', 'Posterior mediastinum', 'Specified parts of peritoneum', 'Overlapping lesion of skin', 'Mucosa of upper lip', 'Undescended testis', 'Overlapping lesions of oropharynx', 'Clitoris', 'Urinary system NOS', 'Overlapping lesion of bones joints and articular cartilage of limbs', 'Brain stem', 'Posterior wall of nasopharynx', 'Hematopoietic system NOS', 'Endocervix', 'Small intestine NOS', 'Pelvis NOS', 'Overlapping lesion of connective subcutaneous and other soft tissues', 'Renal pelvis', 'Meckel diverticulum', 'Peripheral nerves and autonomic nervous system of upper limb and shoulder', 'Lateral wall of nasopharynx', 'Branchial cleft', 'Pyriform sinus', 'Postcricoid region', 'Ileum', 'Sphenoid sinus', 'Posterior wall of bladder', 'Overlapping lesion of bones joints and articular cartilage', 'Greater curvature of stomach NOS', 'Parathyroid gland', 'Skin of other and unspecified parts of face', 'Floor of mouth NOS', 'Optic nerve', 'Upper-outer quadrant of breast', 'Posterior wall of hypopharynx', 'Endocrine gland NOS', 'Long bones of lower limb and associated joints', 'Maxillary sinus', 'Male genital organs NOS', 'Skin NOS', 'Overlapping lesion of peripheral nerves and autonomic nervous system', 'Tonsillar fossa', 'Overlapping lesion of stomach', 'Lower lobe lung', 'Intrahepatic bile duct', 'Cornea NOS', 'Olfactory nerve', 'Lung NOS', 'Urethra', 'Cauda equina', 'Tail of pancreas', 'Overlapping lesion of rectum anus and anal canal']",,Diagnosis
+Metastasis at Diagnosis Site,Metastasis at Diagnosis Site,MetastasisatDiagnosisSite,Text term to identify an anatomic site in which metastatic disease involvement is found.,False,,"['Not Reported', 'Central Nervous System', 'Spinal Cord', 'Bone', 'Kidney', 'Colon', 'Cerebrospinal Fluid', 'Brain', 'Distant Nodes', 'unknown', 'Groin', 'Lung', 'Liver', 'Lymph Node', 'Bone Marrow', 'Adrenal Gland', 'Pelvis', 'Skin', 'Distant Organ', 'Soft Tissue', 'Inguinal', 'Mediastinum', 'Omentum', 'Peritoneal Cavity', 'Peritoneum', 'Pleura', 'Small Intestine', 'Lymph Node NOS', 'Scalp', 'Abdomen', 'Ascites', 'Axillary', 'Ovary', '']",,Diagnosis
+International Prognostic Index,International Prognostic Index,InternationalPrognosticIndex,"The text term used to describe the International Prognostic Index, which classifies the prognosis of patients with aggressive non-Hodgkin's lymphoma.",False,,"['High-Intermediate Risk', 'Low Risk', 'Low-Intermediate Risk', 'High Risk', '']",,Diagnosis
+Anaplasia Present Type,Anaplasia Present Type,AnaplasiaPresentType,"The text term used to describe the morphologic findings indicating the presence of a malignant cellular infiltrate characterized by the presence of large pleomorphic cells, necrosis, and high mitotic activity in a tissue sample.",False,,"['Not Reported', 'unknown', 'Absent', 'Sclerosis', 'Present', 'Focal', 'Equivocal', 'Diffuse', '']",,Diagnosis
+Non Nodal Tumor Deposits,Non Nodal Tumor Deposits,NonNodalTumorDeposits,The yes/no/unknown indicator used to describe the presence of tumor deposits in the pericolic or perirectal fat or in adjacent mesentery away from the leading edge of the tumor.,False,,"['No', 'Yes', 'Not Reported', 'unknown', '']",,Diagnosis
+Synchronous Malignancy,Synchronous Malignancy,SynchronousMalignancy,"A yes/no/unknown indicator used to describe whether the patient had an additional malignant diagnosis at the same time the tumor used for sequencing was diagnosed. If both tumors were sequenced, both tumors would have synchronous malignancies.",False,,"['No', 'Yes', 'Not Reported', 'unknown', '']",,Diagnosis
+First Symptom Prior to Diagnosis,First Symptom Prior to Diagnosis,FirstSymptomPriortoDiagnosis,Text term used to describe the patient's first symptom experienced prior to diagnosis and thought to be related to the disease.,False,,"['Seizures', 'Not Reported', 'Sensory Changes', 'unknown', 'Visual Changes', 'Headaches', 'Motor or Movement Changes', 'Altered Mental Status', '']",,Diagnosis
+Vascular Invasion Present,Vascular Invasion Present,VascularInvasionPresent,The yes/no indicator to ask if large vessel or venous invasion was detected by surgery or presence in a tumor specimen.,False,,"['Not Reported', 'unknown', 'Not Allowed To Collect', 'No', 'Yes - Vascular Invasion Present', '']",,Diagnosis
+Margins Involved Site,Margins Involved Site,MarginsInvolvedSite,The text term used to describe the anatomic sites that were involved in the survival margins.,False,,"['Ureter', 'Gerota Fascia', 'Renal', 'Renal Capsule', 'Perinephric Fat', 'Renal Sinus', 'Renal Vein', 'Parenchyma', '']",,Diagnosis
+Mitosis Karyorrhexis Index,Mitosis Karyorrhexis Index,MitosisKaryorrhexisIndex,Text term that represents the component of the International Neuroblastoma Pathology Classification (INPC) for mitosis-karyorrhexis index (MKI).,False,,"['Not Reported', 'unknown', 'High', 'Intermediate', 'Low', '']",,Diagnosis
+Component,Component,Component,"Category of metadata (e.g. Diagnosis, Biospecimen, scRNA-seq Level 1, etc.); provide the same one for all items/rows.",True,,,,Diagnosis
+Anaplasia Present,Anaplasia Present,AnaplasiaPresent,"Yes/no/unknown/Not Reported indicator used to describe whether anaplasia was present at the
+time of diagnosis.",False,,"['No', 'unknown', 'Not Reported', 'Yes - Anaplasia Present', '']",,Diagnosis
+IRS Group,IRS Group,IRSGroup,"Text term used to describe the classification of rhabdomyosarcoma tumors, as defined by the Intergroup Rhabdomyosarcoma Study (IRS).",False,,"['Not Reported', 'Group I', 'unknown', 'Group IV', 'Group IIc', 'Group IIIb', 'Group III', 'Group IIa', 'Group Ib', 'Group II', 'Group Ia', 'Group IIIa', '']",,Diagnosis
+Tumor Depth,Tumor Depth,TumorDepth,"Numeric value that represents the depth of tumor invasion, measured in millimeters (mm).",False,,,,Diagnosis
+Gleason Grade Group,Gleason Grade Group,GleasonGradeGroup,"The text term used to describe the overall grouping of grades defined by the Gleason grading classification, which is used to determine the aggressiveness of prostate cancer. Note that this grade describes the entire prostatectomy specimen and is not specific to the sample used for sequencing.",False,,"['Group 3', 'Group 1', 'Group 5', 'Group 4', 'Group 2', '']",,Diagnosis
+Metastasis at Diagnosis,Metastasis at Diagnosis,MetastasisatDiagnosis,The text term used to describe the extent of metastatic disease present at diagnosis.,False,,"['Not Reported', 'Regional Metastasis', 'unknown', 'Distant Metastasis', 'No Metastasis', 'Metastasis NOS', '']",,Diagnosis
+AJCC Pathologic N,AJCC Pathologic N,AJCCPathologicN,"The codes that represent the stage of cancer based on the nodes present (N stage) according
+ to criteria based on multiple editions of the AJCC's Cancer Staging Manual.",False,,"['N0 (i-)', 'Not Reported', 'N1b', 'N1bIV', 'N1a', 'unknown', 'N3', 'N1bII', 'N3b', 'N1bI', 'N1bIII', 'N2a', 'N3a', 'N2c', 'N0 (mol-)', 'N2', 'N0 (mol+)', 'N1', 'N0', 'N1mi', 'N4', 'N1c', 'N0 (i+)', 'N3c', 'NX', 'N2b', '']",,Diagnosis
+WHO CNS Grade,WHO CNS Grade,WHOCNSGrade,WHO CNS Grade,False,,"['Not Reported', 'Grade III', 'unknown', 'Grade Not Assigned', 'Grade II', 'Grade I', 'Grade IV', '']",,Diagnosis
+AJCC Pathologic Stage,AJCC Pathologic Stage,AJCCPathologicStage,"The extent of a cancer, especially whether the disease has spread from the original site to
+ other parts of the body based on AJCC staging criteria.",False,,"['Stage IIB', 'Not Reported', 'Stage IB2', 'Stage IB1', 'Stage II', 'Stage IIA1', 'Stage IA2', 'Stage IA', 'Stage I', 'Stage IVB', 'Stage IIC', 'Stage IC', 'Stage 0a', 'unknown', 'Stage IA1', 'Stage IIIB', 'Stage X', 'Stage III', 'Stage IIA', 'Stage 0', 'Stage IVA', 'Stage Tis', 'Stage IIC1', 'Stage IIIC', 'Stage 0is', 'Stage IVC', 'Stage IIIC1', 'Stage IB', 'Stage IIA2', 'Stage IIIC2', 'Stage IIIA', 'Stage IS', 'Stage IV', '']",,Diagnosis
+IGCCCG Stage,IGCCCG Stage,IGCCCGStage,"The text term used to describe the International Germ Cell Cancer Collaborative Group (IGCCCG), a grouping used to further classify metastatic testicular tumors.",False,,"['Not Reported', 'Intermediate Prognosis', 'Poor Prognosis', 'unknown', 'Good Prognosis', '']",,Diagnosis
+Residual Disease,Residual Disease,ResidualDisease,Text terms to describe the status of a tissue margin following surgical resection.,False,,"['Not Reported', 'unknown', 'R1', 'RX', 'R2', 'R0', '']",,Diagnosis
+Morphology,Morphology,Morphology,"The third edition of the International Classification of Diseases for Oncology, published in 2000 used principally in tumor and cancer registries for coding the site (topography) and the histology (morphology) of neoplasms. The study of the structure of the cells and their arrangement to constitute tissues and, finally, the association among these to form organs. In pathology, the microscopic process of identifying normal and abnormal morphologic characteristics in tissues, by employing various cytochemical and immunocytochemical stains. A system of numbered categories for representation of data.",True,,,,Diagnosis
+Primary Gleason Grade,Primary Gleason Grade,PrimaryGleasonGrade,"The text term used to describe the primary Gleason score, which describes the pattern of cells making up the largest area of the tumor. The primary and secondary Gleason pattern grades are combined to determine the patient's Gleason grade group, which is used to determine the aggresiveness of prostate cancer. Note that this grade describes the entire prostatectomy specimen and is not specific to the sample used for sequencing.",False,,"['Pattern 5', 'Pattern 4', 'Pattern 1', 'Pattern 2', 'Pattern 3', '']",,Diagnosis
+Laterality,Laterality,Laterality,"For tumors in paired organs, designates the side on which the cancer originates.",False,,"['Not Reported', 'Unilateral', 'unknown', 'Left', 'Right', 'Midline', 'Bilateral', '']",,Diagnosis
+Non Nodal Regional Disease,Non Nodal Regional Disease,NonNodalRegionalDisease,The text term used to describe whether the patient had non-nodal regional disease.,False,,"['Not Reported', 'unknown', 'Absent', 'Present', 'Indeterminate', '']",,Diagnosis
+Prior Treatment,Prior Treatment,PriorTreatment,A yes/no/unknown/not applicable indicator related to the administration of therapeutic agents received before the body specimen was collected.,False,,"['Not Reported', 'unknown', 'Not Allowed To Collect', 'No', 'Yes', '']",,Diagnosis
+Gross Tumor Weight,Gross Tumor Weight,GrossTumorWeight,"Numeric value used to describe the gross pathologic tumor weight, measured in grams.",False,,,,Diagnosis
+AJCC Pathologic T,AJCC Pathologic T,AJCCPathologicT,"Code of pathological T (primary tumor) to define the size or contiguous extension of the
+ primary tumor (T), using staging criteria from the American Joint Committee on Cancer
+ (AJCC).",False,,"['Not Reported', 'T4c', 'T4e', 'T3', 'T2a2', 'T1a', 'T2', 'T2a1', 'Tis (LCIS)', 'T1a2', 'unknown', 'T2b', 'T3a', 'T1b1', 'T1a1', 'T2d', 'T3d', 'T1', 'T2a', 'T3c', 'T4a', 'T3b', 'T4b', 'TX', 'T4d', 'T1b', 'T2c', 'T4', 'T1c', ""Tis (Paget's)"", 'Ta', 'T1mi', 'Tis', 'T0', 'T1b2', 'Tis (DCIS)', '']",,Diagnosis
+Perineural Invasion Present,Perineural Invasion Present,PerineuralInvasionPresent,A yes/no indicator to ask if perineural invasion or infiltration of tumor or cancer is present.,False,,"['No', 'Yes', 'Not Reported', 'unknown', '']",,Diagnosis
+Ovarian Specimen Status,Ovarian Specimen Status,OvarianSpecimenStatus,The text term used to describe the physical condition of the involved ovary.,False,,"['Not Reported', 'Ovarian Capsule Ruptured', 'unknown', 'Ovarian Capsule Intact', 'Ovarian Capsule Fragmented', '']",,Diagnosis
+Primary Diagnosis,Primary Diagnosis,PrimaryDiagnosis,"Text term used to describe the patient's histologic diagnosis, as described by the World Health Organization's (WHO) International Classification of Diseases for Oncology (ICD-O).",True,,"['Endometrial sarcoma NOS', 'Adult rhabdomyoma', 'Ependymoma NOS', 'Rhabdosarcoma', 'Undifferentiated pleomorphic sarcoma', 'Acute leukemia NOS', 'Carcinoma in adenomatous polyp', 'Rodent ulcer', 'Rhabdoid tumor NOS', 'Small cell osteosarcoma', 'Malignant melanoma regressing', 'Pancreatic endocrine tumor nonfunctioning', 'Duct carcinoma NOS', 'Bronchial adenoma cylindroid', 'Non-Hodgkin lymphoma NOS', 'Transitional cell carcinoma', 'Neurofibrosarcoma', 'Skin appendage carcinoma', 'Melanotic schwannoma', 'Cerebellar liponeurocytoma', 'Squamous cell carcinoma clear cell type', 'Neoplasm metastatic', 'Esophageal intraepithelial neoplasia high grade', 'Large cell carcinoma NOS', 'Adenocarcinoma in a polyp NOS', 'Meningeal melanoma', 'Gastrinoma NOS', 'Rhabdomyosarcoma NOS', 'Myeloma NOS', 'Infiltrating duct and cribriform carcinoma', 'Pulmonary blastoma', 'Tumorlet benign', 'Endometrioid adenocarcinoma NOS', 'Glioblastoma', 'Hodgkin granuloma', 'Malignant lymphoma large cell NOS', 'Dysplastic nevus', 'Rhabdomyoma NOS', 'Adenocarcinoma in polypoid adenoma', 'Intraductal micropapillary carcinoma', 'Non-invasive low grade serous carcinoma', 'Tumor cells benign', 'Mixed tumor malignant NOS', 'Esophageal squamous intraepithelial neoplasia (dysplasia) high grade', 'Non-lymphocytic leukemia NOS', 'Melanocytic nevus', 'Melanoma NOS', 'Renal cell adenocarcinoma', 'Secondary carcinoma', 'Adenocarcinoma of anal ducts', 'Paraganglioma NOS', 'Eosinophilic granuloma', 'Mixed small cell carcinoma', 'Adenocarcinoma endocervical type', 'Tubulo-papillary adenoma', 'Carcinoma metastatic NOS', 'Prostatic intraepithelial neoplasia grade III', 'Carcinoma in a polyp NOS', 'Adenocarcinoma combined with other types of carcinoma', 'Inflammatory carcinoma', 'Papillomatosis NOS', 'Adenocarcinoma of anal glands', 'Malignant melanoma in giant pigmented nevus', 'Interstitial cell tumor benign', 'Chronic lymphatic leukemia', 'Basal cell epithelioma', 'Acute lymphoblastic leukemia-lymphoma NOS', 'Adenocarcinoma in villous adenoma', 'Nonpigmented nevus', 'Mixed medullary-papillary carcinoma', 'Combined small cell-squamous cell carcinoma', 'Lobular carcinoma NOS', 'Malignant lymphoma mixed cell type diffuse', 'B lymphoblastic leukemia/lymphoma with hyperdiploidy', 'Chronic myelogenous leukemia Philadelphia chromosome (Ph 1) positive', 'Malignant lymphoma lymphocytic nodular NOS', 'Inflammatory adenocarcinoma', 'Carcinoma in situ in a polyp NOS', 'Teratoma NOS', 'Serous surface papillary carcinoma', 'Monocytic leukemia NOS', 'Malignant lymphoma NOS', 'Dermatofibroma NOS', 'Melanotic psammomatous MPNST', 'Adenocarcinoma in situ in tubular adenoma', 'Tumor secondary', 'Hepatocarcinoma', 'Pigmented basal cell carcinoma', 'c-ALL', 'Myelocytic leukemia NOS', 'Meningioma NOS', 'Ewing sarcoma', 'Mixed adenocarcinoma and squamous cell carcinoma', 'Bronchiolo-alveolar adenocarcinoma NOS', 'Undifferentiated leukaemia', 'Chondrosarcoma grade 2/3', 'Neoplasm secondary', 'Mixed pancreatic endocrine and exocrine tumor malignant', 'Precancerous melanosis NOS', 'Epithelial tumor malignant', 'Malignant melanoma in precancerous melanosis', 'Intraductal carcinoma NOS', 'Papillary epidermoid carcinoma', 'Osteoblastoma NOS', 'Classical Hodgkin lymphoma lymphocyte depletion diffuse fibrosis', 'Tubular adenoma NOS', 'Liver cell carcinoma', 'Small cell neuroendocrine carcinoma', 'Classical Hodgkin lymphoma lymphocyte-rich', 'Carcinoma in situ in adenomatous polyp', 'Splenic marginal zone B-cell lymphoma', 'Medulloblastoma NOS', 'Lymphocytic leukemia NOS', 'Splenic marginal zone lymphoma NOS', 'Astrocytoma anaplastic', 'Papilloma of bladder', 'Intraductal and lobular carcinoma', 'Intravascular B-cell lymphoma', 'Nephroblastoma NOS', 'Neuroendocrine carcinoma NOS', 'Malignant lymphoma nodular NOS', 'Medullary carcinoma NOS', 'T lymphoblastic leukemia/lymphoma', 'Classical Hodgkin lymphoma lymphocyte depletion NOS', 'Malignant lymphoma non-Hodgkin NOS', 'Non-small cell carcinoma', 'Acute promyelocytic leukemia NOS', 'Liver cell adenoma', 'Neoplasm malignant', 'Adenocarcinoma in situ in adenomatous polyp', 'Adenocarcinoma NOS', 'Duct carcinoma desmoplastic type', 'Burkitt tumor', 'Hodgkin disease NOS', 'Malignant lymphoma immunoblastic NOS', 'Malignant melanoma in junctional nevus', 'Unclassified tumor malignant uncertain whether primary or metastatic', 'Chronic myeloid leukemia NOS', 'Serous cystadenocarcinoma NOS', 'Chronic myelocytic leukemia NOS', 'Pleomorphic lobular carcinoma', 'Cerebellar sarcoma NOS', 'Chronic granulocytic leukemia Philadelphia chromosome (Ph1) positive', 'Pigmented adenoma', 'Papillotubular adenocarcinoma', 'Mucosal-associated lymphoid tissue lymphoma', 'Capillary lymphangioma', 'Neoplasm NOS', 'Spindle cell carcinoma NOS', 'Familial adenomatous polyposis', 'Hodgkin paragranuloma NOS', 'Mixed medullary-follicular carcinoma', 'Tubular carcinoma', 'Medullary osteosarcoma', 'Burkitt lymphoma NOS (Includes all variants)', 'unknown', 'Hepatoid carcinoma', 'Transitional carcinoma', 'Renal cell carcinoma spindle cell', 'Melanotic neurofibroma', 'Neurosarcoma', 'Gastrin cell tumor malignant', 'Small congenital nevus', 'Pro-B ALL', 'Acinar cell carcinoma', 'Basophil adenocarcinoma', 'Malignant lymphoma small B lymphocytic NOS', 'Tubulovillous adenoma NOS', 'Lobular carcinoma noninfiltrating', 'Papillary glioneuronal tumor', 'Bronchiolo-alveolar carcinoma non-mucinous', 'Secretory carcinoma of breast', 'Papillomatosis glandular', 'Renal cell carcinoma NOS', 'Haemangioblastoma', 'Hodgkin lymphoma mixed cellularity NOS', 'Adenocarcinoma metastatic NOS', 'Adenocarcinoma in situ non-mucinous', 'Adenocarcinoma pancreatobiliary type', 'Not Reported', 'Peripheral T-cell lymphoma NOS', 'Astrocytoma NOS', 'Ganglioglioma NOS', 'Tumor cells uncertain whether benign or malignant', 'Acute myeloid leukemia NOS', 'Unclassified tumor uncertain whether benign or malignant', 'Epidermoid carcinoma NOS', 'Malignant lymphoma lymphocytic NOS', 'Tumor cells NOS', 'Mixed tumor NOS', 'Tubular adenocarcinoma', 'Basophil adenoma', 'Hepatocholangiocarcinoma', 'Paget disease and infiltrating duct carcinoma of breast', 'Pancreatobiliary neoplasm non-invasive', 'Dermal nevus', 'Chronic myeloproliferative disease NOS', 'Bronchiolar carcinoma', 'Intracystic papilloma', 'Hepatocellular adenoma', 'Adenocarcinoma in situ in a polyp NOS', 'Bronchiolo-alveolar carcinoma Clara cell', 'Bronchiolo-alveolar carcinoma NOS', 'Transitional cell carcinoma in situ', 'Central neurocytoma', 'Bile duct adenoma', 'Chronic neutrophilic leukemia', 'Preleukemic syndrome', 'Gastrinoma malignant', 'Acute lymphoblastic leukemia mature B-cell type', 'Lobular adenocarcinoma', 'Unclassified tumor malignant', 'Sclerosing hemangioma', 'Melanocytoma NOS', 'Undifferentiated epithelioid sarcoma', 'Papillary microcarcinoma', 'Rhabdomyosarcoma with ganglionic differentiation', 'Bronchio-alveolar carcinoma mucinous', 'Adenocarcinoma in adenomatous polyp', 'Paget disease of breast', 'Classical Hodgkin lymphoma nodular sclerosis NOS', 'Lobular and ductal carcinoma', 'Pulmonary adenomatosis', 'Myeloid leukemia NOS', 'Mixed squamous cell and glandular papilloma', 'Melanotic progonoma', 'Tubulocystic renal cell carcinoma', 'Eosinophil adenoma', 'Pancreatic endocrine tumor benign', 'Malignant lymphoma lymphoblastic NOS', 'Chronic myelomonocytic leukemia NOS', 'Endometrioid carcinoma NOS', 'Bronchiolo-alveolar carcinoma indeterminate type', 'Intraepidermal carcinoma NOS', 'Papillary adenocarcinoma NOS', 'Intraductal tubular-papillary neoplasm low grade', 'Papillary renal cell carcinoma', 'Undifferentiated spindle cell sarcoma', 'Intraductal papillary adenocarcinoma NOS', 'Eosinophilic leukemia', 'Tubulopapillary adenocarcinoma', 'Malignant lymphoma mixed cell type follicular', 'Malignant melanoma in Hutchinson melanotic freckle', 'Liposarcoma well differentiated', 'Papilloma NOS', 'Ductal carcinoma NOS', 'Neuroepithelioma NOS', 'Combined small cell carcinoma', 'Hodgkin lymphoma nodular sclerosis NOS', 'Paget disease and intraductal carcinoma of breast', 'Melanotic MPNST', 'Hepatocellular carcinoma NOS', 'Classical Hodgkin lymphoma nodular sclerosis grade 2', 'Lobular carcinoma in situ NOS', 'T-cell lymphoma NOS', 'Malignant lymphoma large B-cell diffuse NOS', 'Melanoma malignant of soft parts', 'Basal cell adenocarcinoma', 'Diffuse astrocytoma IDH-mutant', 'Eosinophil carcinoma', 'Tumor cells malignant', 'Pituitary adenoma NOS', 'Diffuse astrocytoma low grade', 'Melanoma in situ', 'Adult T-cell lymphoma/leukemia', 'Bronchial-associated lymphoid tissue lymphoma', 'Chondroma NOS', 'Precursor B-cell lymphoblastic lymphoma', 'Rhabdoid meningioma', 'Papillotubular adenoma', 'Capillary hemangioma', 'Melanotic neuroectodermal tumor', 'Malignant lymphoma lymphocytic diffuse NOS', 'Adenocarcinoma intestinal type', 'Paget disease extramammary', 'Squamous cell carcinoma adenoid', 'Undifferentiated round cell sarcoma', 'Chronic granulocytic leukemia BCR/ABL', 'Diffuse large B-cell lymphoma NOS', 'Paget disease mammary', 'Paraganglioma benign', 'Adenocarcinoma diffuse type', 'Primary amyloidosis', 'Adult T-cell lymphoma', 'Meningioma malignant', 'Chronic monocytic leukemia', 'Papillary adenoma NOS', 'Epithelial tumor benign', 'Acute lymphoid leukemia', 'Papillary carcinoma in situ', 'Neurofibroma NOS', 'Therapy related myeloid neoplasm', 'Gastrointestinal stromal tumor malignant', 'Neoplasm uncertain whether benign or malignant', 'Micropapillary carcinoma NOS', 'Pleomorphic lipoma', 'Pancreatobiliary-type carcinoma', 'Papillary adenocarcinoma follicular variant', 'Endometrioid adenofibroma NOS', 'Neuroblastoma NOS', 'Lymphatic leukemic NOS', 'Esophageal glandular dysplasia (intraepithelial neoplasia) high grade', 'Pancreatoblastoma', 'Infiltrating basal cell carcinoma NOS', 'Astrocytoma low grade', 'Tumor metastatic', 'Small cell carcinoma NOS', 'Undifferentiated uterine sarcoma', 'Burkitt cell leukemia', 'Pleomorphic lobular carcinoma in situ', 'Pituitary carcinoma NOS', 'Bile duct adenocarcinoma', 'Cervical intraepithelial neoplasia grade III', 'Intradermal nevus', 'Classical Hodgkin lymphoma nodular sclerosis grade 1', 'Papillary transitional cell carcinoma', 'T-cell large granular lymphocytic leukemia', 'B-cell lymphocytic leukemia/small lymphocytic lymphoma', 'Basophil carcinoma', 'Squamous cell carcinoma in situ NOS', 'Haemangiosarcoma', 'Neoplasm malignant uncertain whether primary or metastatic', 'Renal cell carcinoma unclassified', 'Lymphoma NOS', 'Osteosarcoma NOS', 'Intraductal carcinoma and lobular carcinoma in situ', 'Rhabdoid sarcoma', 'Bile duct carcinoma', 'Malignant lymphoma Hodgkin', 'Bronchio-alveolar carcinoma mixed mucinous and non-mucinous', 'Esophageal squamous intraepithelial neoplasia (dysplasia) low grade', 'Basal cell tumor', 'Composite Hodgkin and non-Hodgkin lymphoma', 'Pancreatic endocrine tumor malignant', 'Acute lymphoblastic leukemia precursor cell type', 'Pro-T ALL', 'Epidermoid carcinoma in situ NOS', 'Intraductal carcinoma clinging', 'Adenocarcinoma in situ NOS', 'Combined small cell-adenocarcinoma', 'Adenocarcinoma in situ mucinous', 'Papillary serous cystadenocarcinoma', 'Precursor B-cell lymphoblastic leukemia', 'Neoplasm benign', 'Paraganglioma malignant', 'Kaposi sarcoma', 'Acute lymphatic leukemia', 'Papillary urothelial carcinoma', 'Bronchial adenoma NOS', 'Acute lymphocytic leukemia', 'Pigmented nevus NOS', 'Pancreatic microadenoma', 'Tubular androblastoma with lipid storage', 'Melanocytoma eyeball', 'Combined hepatocellular carcinoma and cholangiocarcinoma', 'Cancer', 'Tumor malignant NOS', 'Intraductal papillary adenocarcinoma with invasion', 'Mucous adenocarcinoma', 'Undifferentiated sarcoma', 'Papillary serous adenocarcinoma', 'Gastrin cell tumor', 'Burkitt-like lymphoma', 'B cell lymphoma NOS', 'Cervical intraepithelial neoplasia low grade', 'Bronchial adenoma carcinoid', 'Intraductal tubulopapillary neoplasm', 'Melanotic medulloblastoma', 'Papillary and follicular carcinoma', 'Renal medullary carcinoma', 'Tumor benign', 'Papillary tumor of the pineal region', 'Splenic diffuse red pulp small B-cell lymphoma', 'Oat cell carcinoma', 'Meningeal melanocytoma', 'Interstitial cell tumor NOS', 'Basal cell carcinoma NOS', 'Duct adenoma NOS', 'Nevus NOS', 'Intraductal tubular-papillary neoplasm high grade', 'Papillary meningioma', 'Mammary carcinoma in situ', 'B lymphoblastic leukemia/lymphoma with hypodiploidy (Hypodiploid ALL)', 'Intraductal papillary carcinoma', 'Combined/mixed carcinoid and adenocarcinoma', 'Carcinoma diffuse type', 'Spindle cell melanoma NOS', 'Interstitial cell tumor malignant', 'Chronic lymphoid leukemia', 'Typical carcinoid', 'Papillary carcinoma NOS', 'Chronic myeloproliferative disorder', 'Acute lymphoblastic leukemia NOS', 'Renal carcinoma collecting duct type', 'Pleomorphic adenoma', 'Malignant melanoma in congenital melanocytic nevus', 'Hepatoid adenocarcinoma', 'Osteoblastoma malignant', 'Chronic leukemia NOS', 'Pagetoid reticulosis', 'Chronic granulocytic leukemia NOS', 'Renal cell carcinoma chromophobe type', 'Duct cell carcinoma', 'Cementoma NOS', 'Classical Hodgkin lymphoma mixed cellularity NOS', 'Splenic B-cell lymphoma/leukemia unclassifiable', 'B-ALL', 'Infiltrating duct and colloid carcinoma', 'Chronic myelogenous leukemia BCR-ABL positive', 'Papillary serous cystadenoma NOS', 'Tubulolobular carcinoma', 'Chronic lymphocytic leukemia B-cell type (includes all variants of BCLL)', 'Eosinophil adenocarcinoma', 'Tubular androblastoma NOS', 'Classical Hodgkin lymphoma lymphocyte depletion reticular', 'Ductal carcinoma in situ NOS', 'Intraductal carcinoma solid type', 'Tumor embolus', 'Pulmonary artery intimal sarcoma', 'Liposarcoma differentiated', 'Teratoma malignant NOS', 'Splenic lymphoma with villous lymphocytes', 'Sclerosing hepatic carcinoma', 'Malignant lymphoma mixed cell type nodular', 'Carcinoma intestinal type', 'Infiltrating duct carcinoma NOS', 'Malignant melanoma NOS', 'Myoepithelioma', 'Hodgkin lymphoma NOS', 'Bile duct cystadenocarcinoma', 'Carcinoma in pleomorphic adenoma', 'Chronic myelomonocytic leukemia Type 1', 'Acute myeloid leukemia MLL', 'Acute myeloid leukemia minimal differentiation', 'Unclassified tumor borderline malignancy', 'Precursor T-cell lymphoblastic leukemia', 'Adenocarcinoma in tubular adenoma', 'Esophageal glandular dysplasia (intraepithelial neoplasia) low grade', 'Central neuroblastoma', 'Mixed adenocarcinoma and epidermoid carcinoma', 'Bronchiolar adenocarcinoma', 'Diffuse astrocytoma IDH-wildtype', 'Medullary adenocarcinoma', 'Sarcoma NOS', 'Malignant lymphoma large B-cell NOS', 'Peripheral T-cell lymphoma large cell', 'Meningioma anaplastic', 'Endometrioid adenoma NOS', 'Tumor NOS', 'Papillary adenofibroma', 'Melanoameloblastoma', 'Undifferentiated high-grade pleomorphic sarcoma', 'Acute myelomonocytic leukemia', 'T-cell large granular lymphocytosis', 'Intraepidermal squamous cell carcinoma Bowen type', 'Glioma malignant', 'Chronic lymphocytic leukemia', 'Mixed pineal tumor', 'Acute basophilic leukaemia', 'Precursor T-cell lymphoblastic lymphoma', 'Renal cell carcinoma sarcomatoid', 'Glioma NOS', 'Carcinoma NOS', 'Unclassified tumor benign', 'Neurofibromatosis NOS', 'Bronchiolo-alveolar carcinoma Clara cell and goblet cell type', 'Pleomorphic carcinoma', 'Chronic myelomonocytic leukemia in transformation', 'Precursor cell lymphoblastic leukemia NOS', 'Preleukemia', 'Papillary cystadenoma NOS', 'High-grade serous carcinoma', 'B lymphoblastic leukemia/lymphoma NOS', 'Bile duct cystadenoma', 'Liposarcoma NOS', 'Intraductal carcinoma noninfiltrating NOS', 'Carcinoma undifferentiated NOS', 'Tubular carcinoid', 'Pleomorphic liposarcoma', 'Juvenile myelomonocytic leukemia', 'Lymphoblastic leukemia NOS', 'Lymphoblastoma', 'Bronchiolo-alveolar carcinoma goblet cell type', 'Papillary squamous cell carcinoma', 'Squamous cell carcinoma NOS', 'Basal cell adenoma', 'Duct adenocarcinoma NOS', 'Small cell sarcoma', 'Acute leukemia Burkitt type', 'Combined small cell-large carcinoma', 'Carcinosarcoma NOS', 'Classical Hodgkin lymphoma nodular sclerosis cellular phase', 'Malignancy', 'Diffuse melanocytosis', 'Pancreatic endocrine tumor NOS', 'Hodgkin sarcoma', 'Combined large cell neuroendocrine carcinoma', 'Adenocarcinoid tumor', 'Papillary squamous cell carcinoma in situ', 'Multiple myeloma', 'Carcinoma in situ NOS', 'Malignant lymphoma diffuse NOS', 'Chronic myelomonocytic leukemia Type II', 'Carcinoma anaplastic NOS', 'Intraductal adenocarcinoma noninfiltrating NOS']",,Diagnosis
+Days to Diagnosis,Days to Diagnosis,DaystoDiagnosis,Number of days between the date used for index and the date the patient was diagnosed with the malignant disease.,False,,,,Diagnosis
+Days to Recurrence,Days to Recurrence,DaystoRecurrence,Number of days between the date used for index and the date the patient's disease recurred.,False,True,,"Progression or Recurrence -is- ""Yes - Progression or Recurrence""",Diagnosis
+Days to Progression,Days to Progression,DaystoProgression,Number of days between the date used for index and the date the patient's disease progressed.,False,True,,"Progression or Recurrence -is- ""Yes - Progression or Recurrence""",Diagnosis
+Days to Progression Free,Days to Progression Free,DaystoProgressionFree,Number of days between the date used for index and the date the patient's disease was formally confirmed as progression-free.,False,True,,"Progression or Recurrence -is- ""Yes - Progression or Recurrence""",Diagnosis
+Progression or Recurrence Type,Progression or Recurrence Type,ProgressionorRecurrenceType,The text term used to describe the type of progressive or recurrent disease or relapsed disease.,False,True,"['Not Reported', 'unknown', 'Local', 'Biochemical', 'Regional', 'Distant', '']","Progression or Recurrence -is- ""Yes - Progression or Recurrence""",Diagnosis
+Progression or Recurrence Anatomic Site,Progression or Recurrence Anatomic Site,ProgressionorRecurrenceAnatomicSite,The text term used to describe the anatomic site of resection; biopsy; tissue or organ of biospecimen origin; progression or recurrent disease; treatment,False,True,"['Lymph nodes of multiple regions', 'Overlapping lesion of lung', 'Peripheral nerves and autonomic nervous system of abdomen', 'Placenta', 'Thymus', 'Kidney NOS', 'Lesser curvature of stomach NOS', 'Ascending colon', 'Vertebral column', 'Axillary tail of breast', 'Cortex of adrenal gland', 'Brain NOS', 'Cheek mucosa', 'Overlapping lesion of floor of mouth', 'Overlapping lesion of accessory sinuses', 'Intra-abdominal lymph nodes', 'Connective subcutaneous and other soft tissues of pelvis', 'External upper lip', 'Esophagus NOS', 'Vestibule of mouth', 'Waldeyer ring', 'Lymph nodes of head face and neck', 'Adrenal gland NOS', 'Short bones of upper limb and associated joints', 'Meninges NOS', 'Short bones of lower limb and associated joints', 'Other ill-defined sites', 'Upper lobe lung', 'Ventricle NOS', 'Head of pancreas', 'Orbit NOS', 'Pituitary gland', 'Frontal sinus', 'Dorsal surface of tongue NOS', 'Spleen', 'Skin of upper limb and shoulder', 'Supraglottis', 'Anal canal', 'Nipple', 'Ureteric orifice', 'Overlapping lesion of endocrine glands and related structures', 'Upper-inner quadrant of breast', 'Overlapping lesion of tonsil', 'Cardia NOS', 'Ciliary body', 'Bone marrow', 'Extrahepatic bile duct', 'Ethmoid sinus', 'Oropharynx NOS', 'Base of tongue NOS', 'Lacrimal gland', 'Pharynx NOS', 'Submandibular gland', 'Parotid gland', 'Gastrointestinal tract NOS', 'Lymph nodes of inguinal region or leg', 'Broad ligament', 'Medulla of adrenal gland', 'Body of stomach', 'Paraurethral gland', 'Scrotum NOS', 'Hypopharynx NOS', 'Intrathoracic lymph nodes', 'Pylorus', 'Isthmus uteri', 'Upper limb NOS', 'Sigmoid colon', 'Major salivary gland NOS', 'Mucosa of lip NOS', 'Main bronchus', 'Uterus NOS', 'Lower-inner quadrant of breast', 'Other specified parts of pancreas', 'Fundus of stomach', 'Ventral surface of tongue NOS', 'Overlapping lesion of vulva', 'Vallecula', 'Anterior wall of nasopharynx', 'Posterior wall of oropharynx', 'Sublingual gland', 'Fundus uteri', 'Anterior wall of bladder', 'Spinal cord', 'Cerebrum', 'Superior wall of nasopharynx', 'Descended testis', 'Rectum NOS', 'Peripheral nerves and autonomic nervous system of trunk NOS', 'External lower lip', 'Mucosa of lower lip', 'unknown', 'Connective subcutaneous and other soft tissues of lower limb and hip', 'Border of tongue', 'Cervix uteri', 'Connective subcutaneous and other soft tissues NOS', 'Tonsil NOS', 'Temporal lobe', 'Trachea', 'Lower gum', 'Head face or neck NOS', 'Glottis', 'Overlapping lesion of palate', 'Middle lobe lung', 'Other specified parts of female genital organs', 'Not Reported', 'Thyroid gland', 'Vulva NOS', 'Lymph nodes of axilla or arm', 'Overlapping lesion of small intestine', 'Ill-defined sites within respiratory system', 'Connective subcutaneous and other soft tissues of trunk NOS', 'Overlapping lesion of urinary organs', 'Thorax NOS', 'Ampulla of Vater', 'Lymph node NOS', 'Corpus uteri', 'Biliary tract NOS', 'Acoustic nerve', 'Reticuloendothelial system NOS', 'Soft palate NOS', 'Conjunctiva', 'Cervical esophagus', 'Myometrium', 'Ovary', 'Overlapping lesion of cervix uteri', 'Epididymis', 'Exocervix', 'Overlapping lesion of respiratory system and intrathoracic organs', 'Cloacogenic zone', 'Overlapping lesion of esophagus', 'Dome of bladder', 'Spermatic cord', 'Thoracic esophagus', 'Vagina NOS', 'Blood', 'Female genital tract NOS', 'Other specified parts of male genital organs', 'Overlapping lesion of hypopharynx', 'Overlapping lesion of nasopharynx', 'Long bones of upper limb scapula and associated joints', 'Cranial nerve NOS', 'Glans penis', 'Occipital lobe', 'Bladder NOS', 'Aortic body and other paraganglia', 'Appendix', 'Subglottis', 'Stomach NOS', 'Mandible', 'Testis NOS', 'Overlapping lesion of bladder', 'Urachus', 'Bladder neck', 'Overlapping lesion of major salivary glands', 'Skin of lip NOS', 'Lateral floor of mouth', 'Overlapping lesion of lip', 'Hard palate', 'Retroperitoneum', 'Central portion of breast', 'Overlapping lesion of digestive system', 'Overlapping lesion of penis', 'Spinal meninges', 'Connective subcutaneous and other soft tissues of head face and neck', 'Overlapping lesion of lip oral cavity and pharynx', 'Body of pancreas', 'Pleura NOS', 'Pancreatic duct', 'Overlapping lesion of corpus uteri', 'Eyelid', 'Splenic flexure of colon', 'Mediastinum NOS', 'Labium majus', 'Body of penis', 'Transverse colon', 'Overlapping lesion of pancreas', 'Rib sternum clavicle and associated joints', 'Trigone of bladder', 'External ear', 'Laryngeal cartilage', 'Mouth NOS', 'Abdomen NOS', 'Nasopharynx NOS', 'Craniopharyngeal duct', 'Peripheral nerves and autonomic nervous system of thorax', 'Tongue NOS', 'Hypopharyngeal aspect of aryepiglottic fold', 'Parietal lobe', 'Bone of limb NOS', 'Peritoneum NOS', 'Abdominal esophagus', 'Palate NOS', 'Round ligament', 'Prepuce', 'Islets of Langerhans', 'Gastric antrum', 'Peripheral nerves and autonomic nervous system of pelvis', 'Overlapping lesion of tongue', 'Skin of trunk', 'Fallopian tube', 'Cecum', 'Pancreas NOS', 'Middle ear', 'Overlapping lesion of heart mediastinum and pleura', 'Pelvic lymph nodes', 'Connective subcutaneous and other soft tissues of thorax', 'Lip NOS', 'Bone NOS', 'Cerebellum NOS', 'Connective subcutaneous and other soft tissues of upper limb and shoulder', 'Lower third of esophagus', 'Hepatic flexure of colon', 'Autonomic nervous system NOS', 'Tonsillar pillar', 'Anterior surface of epiglottis', 'Lateral wall of bladder', 'Jejunum', 'Retina', 'unknown primary site', 'Skin of lower limb and hip', 'Lingual tonsil', 'Breast NOS', 'Skin of scalp and neck', 'Overlapping lesion of retroperitoneum and peritoneum', 'Overlapping lesion of eye and adnexa', 'Parametrium', 'Upper respiratory tract NOS', 'Bones of skull and face and associated joints', 'Labium minus', 'Prostate gland', 'Connective subcutaneous and other soft tissues of abdomen', 'Overlapping lesion of other and unspecified parts of mouth', 'External lip NOS', 'Peripheral nerves and autonomic nervous system of lower limb and hip', 'Retromolar area', 'Middle third of esophagus', 'Ureter', 'Frontal lobe', 'Cerebral meninges', 'Liver', 'Colon NOS', 'Descending colon', 'Overlapping lesion of female genital organs', 'Lateral wall of oropharynx', 'Overlapping lesion of ill-defined sites', 'Choroid', 'Lower-outer quadrant of breast', 'Upper third of esophagus', 'Anus NOS', 'Pelvic bones sacrum coccyx and associated joints', 'Overlapping lesion of brain and central nervous system', 'Anterior floor of mouth', 'Nervous system NOS', 'Eye NOS', 'Overlapping lesion of breast', 'Intestinal tract NOS', 'Carotid body', 'Heart', 'Gum NOS', 'Larynx NOS', 'Uterine adnexa', 'Upper gum', 'Duodenum', 'Accessory sinus NOS', 'Anterior 2/3 of tongue NOS', 'Rectosigmoid junction', 'Anterior mediastinum', 'Peripheral nerves and autonomic nervous system of head face and neck', 'Penis NOS', 'Endometrium', 'Commissure of lip', 'Overlapping lesion of larynx', 'Lower limb NOS', 'Overlapping lesion of colon', 'Nasal cavity', 'Overlapping lesion of brain', 'Overlapping lesion of biliary tract', 'Pineal gland', 'Gallbladder', 'Overlapping lesion of male genital organs', 'Uvula', 'Posterior mediastinum', 'Specified parts of peritoneum', 'Overlapping lesion of skin', 'Mucosa of upper lip', 'Undescended testis', 'Overlapping lesions of oropharynx', 'Clitoris', 'Urinary system NOS', 'Overlapping lesion of bones joints and articular cartilage of limbs', 'Brain stem', 'Posterior wall of nasopharynx', 'Hematopoietic system NOS', 'Endocervix', 'Small intestine NOS', 'Pelvis NOS', 'Overlapping lesion of connective subcutaneous and other soft tissues', 'Renal pelvis', 'Meckel diverticulum', 'Peripheral nerves and autonomic nervous system of upper limb and shoulder', 'Lateral wall of nasopharynx', 'Branchial cleft', 'Pyriform sinus', 'Postcricoid region', 'Ileum', 'Sphenoid sinus', 'Posterior wall of bladder', 'Overlapping lesion of bones joints and articular cartilage', 'Greater curvature of stomach NOS', 'Parathyroid gland', 'Skin of other and unspecified parts of face', 'Floor of mouth NOS', 'Optic nerve', 'Upper-outer quadrant of breast', 'Posterior wall of hypopharynx', 'Endocrine gland NOS', 'Long bones of lower limb and associated joints', 'Maxillary sinus', 'Male genital organs NOS', 'Skin NOS', 'Overlapping lesion of peripheral nerves and autonomic nervous system', 'Tonsillar fossa', 'Overlapping lesion of stomach', 'Lower lobe lung', 'Intrahepatic bile duct', 'Cornea NOS', 'Olfactory nerve', 'Lung NOS', 'Urethra', 'Cauda equina', 'Tail of pancreas', 'Overlapping lesion of rectum anus and anal canal', '']","Progression or Recurrence -is- ""Yes - Progression or Recurrence""",Diagnosis
+Start Days from Index,Start Days from Index,StartDaysfromIndex,"Number of days from the date of birth (index date) to the date of an event (e.g. exposure to environmental factor, treatment start, etc.). If not applicable please enter 'Not Applicable'",True,,,,PancreaticCancerTier3
+Pancreatic IPMN Pathology Epithelial Subtype,Pancreatic IPMN Pathology Epithelial Subtype,PancreaticIPMNPathologyEpithelialSubtype,The Intraductal Papillary Mucinous Neoplasm (IPMN) epithelial cell subtype based on the gross and microscopic examination of a pancreatic neoplasm specimen,False,,"['Gastric Foveolar', 'Other', 'Intestinal', 'Pancreatobiliary', 'Intraductal Tubopapillary', 'unknown', 'Not Reported', 'Oncocytic', '']",,PancreaticCancerTier3
+Component,Component,Component,"Category of metadata (e.g. Diagnosis, Biospecimen, scRNA-seq Level 1, etc.); provide the same one for all items/rows.",True,,,,PancreaticCancerTier3
+Pancreas Precancer Histopathologic Grade,Pancreas Precancer Histopathologic Grade,PancreasPrecancerHistopathologicGrade,The grade of precancerous pancreatic tissue based on microscopic study of characteristic tissue abnormalities by employing various cytochemical and immunocytochemical stains.,False,,"['IPMN-Borderline', 'IPMN-Adenoma', 'PanIN 3', 'unknown', 'PanIN 1A', 'IPMN-Carcinoma in situ', 'PanIN 2', 'IPMN-Invasive carcinoma', 'Not Reported', 'PanIN 1B', 'PanIN 1', '']",,PancreaticCancerTier3
+Stop Days from Index,Stop Days from Index,StopDaysfromIndex,"Number of days from the date of birth (index date) to the end date of the event (e.g. exposure to environmental factor, treatment start, etc.). Note: if the event occurs at a single time point, e.g. a diagnosis or a lab test, the values for this column is 'Not Applicable'",False,,,,PancreaticCancerTier3
+Timepoint Label,Timepoint Label,TimepointLabel,"Label to identify the time point at which the clinical data or biospecimen was obtained (e.g. Baseline, End of Treatment, Overall survival, Final). NO PHI/PII INFORMATION IS ALLOWED.",True,,,,PancreaticCancerTier3
+Pancreatic Duct Final Pathology Type,Pancreatic Duct Final Pathology Type,PancreaticDuctFinalPathologyType,The final pathology result of the pancreatic duct communication type.,False,,"['Main Duct', 'Not Specified', 'None', 'Mixed', 'Not Reported', 'Side-Branch', '']",,PancreaticCancerTier3
+HTAN Participant ID,HTAN Participant ID,HTANParticipantID,HTAN ID associated with a patient based on HTAN ID SOP (eg HTANx_yyy ),True,,,,PancreaticCancerTier3
+Treatment or Therapy,Treatment or Therapy,TreatmentorTherapy,A yes/no/unknown/not applicable indicator related to the administration of therapeutic agents received.,False,,"['No', 'unknown', 'Not Reported', 'Yes', '']",,Therapy
+Treatment Intent Type,Treatment Intent Type,TreatmentIntentType,Text term to identify the reason for the administration of a treatment regimen. [Manually-curated],False,,"['Cure', 'Not Reported', 'Neoadjuvant', 'Prevention', 'Palliative', 'unknown', 'Adjuvant', 'Cancer Control', '']",,Therapy
+Number of Cycles,Number of Cycles,NumberofCycles,The numeric value used to describe the number of cycles of a specific treatment or regimen the patient received.,False,,,,Therapy
+Treatment Frequency,Treatment Frequency,TreatmentFrequency,The text term used to describe the frequency the patient received an agent or regimen.,False,,"['Every 24 Hours', 'Not Reported', 'Once Weekly', 'Every Hour', 'Four Times Daily', 'Twice Daily', 'Three Times Daily', 'Every Other Day', 'Twice Weekly', 'Five Times Daily', 'unknown', '']",,Therapy
+Treatment Anatomic Site,Treatment Anatomic Site,TreatmentAnatomicSite,The text term used to describe the anatomic site of resection; biopsy; tissue or organ of biospecimen origin; progression or recurrent disease; treatment,False,,"['Floor of mouth NOS', 'Waldeyer ring', 'Fundus uteri', 'Larynx NOS', 'Dorsal surface of tongue NOS', 'Vulva NOS', 'Urethra', 'Ureter', 'Spermatic cord', 'Parotid gland', 'Overlapping lesion of skin', 'Nervous system NOS', 'Maxillary sinus', 'Other specified parts of female genital organs', 'Skin NOS', 'Overlapping lesion of rectum anus and anal canal', 'Gastrointestinal tract NOS', 'Overlapping lesion of tongue', 'Upper respiratory tract NOS', 'Frontal lobe', 'Oropharynx NOS', 'Overlapping lesion of nasopharynx', 'Pancreas NOS', 'Overlapping lesion of heart mediastinum and pleura', 'Parathyroid gland', 'Autonomic nervous system NOS', 'Pharynx NOS', 'Head face or neck NOS', 'Jejunum', 'Peripheral nerves and autonomic nervous system of thorax', 'Retroperitoneum', 'Pyriform sinus', 'Eyelid', 'Mediastinum NOS', 'Endometrium', 'Overlapping lesion of bones joints and articular cartilage', 'Connective subcutaneous and other soft tissues of trunk NOS', 'Postcricoid region', 'Lung NOS', 'Splenic flexure of colon', 'Tonsil NOS', 'Rib sternum clavicle and associated joints', 'Temporal lobe', 'Rectum NOS', 'Medulla of adrenal gland', 'Reticuloendothelial system NOS', 'Vertebral column', 'Paraurethral gland', 'Prostate gland', 'Overlapping lesion of vulva', 'Gastric antrum', 'Peripheral nerves and autonomic nervous system of lower limb and hip', 'Meninges NOS', 'Mouth NOS', 'Dome of bladder', 'Peripheral nerves and autonomic nervous system of abdomen', 'Lower limb NOS', 'Descended testis', 'Cerebellum NOS', 'Optic nerve', 'Undescended testis', 'Ascending colon', 'Labium majus', 'Placenta', 'Overlapping lesion of biliary tract', 'Body of stomach', 'Connective subcutaneous and other soft tissues of thorax', 'Posterior mediastinum', 'Uterine adnexa', 'Anterior 2/3 of tongue NOS', 'Uvula', 'Lymph nodes of axilla or arm', 'Bones of skull and face and associated joints', 'Sigmoid colon', 'Posterior wall of oropharynx', 'Kidney NOS', 'Overlapping lesion of retroperitoneum and peritoneum', 'Overlapping lesion of respiratory system and intrathoracic organs', 'Sphenoid sinus', 'Bladder NOS', 'Axillary tail of breast', 'Cervical esophagus', 'External ear', 'Parametrium', 'Brain NOS', 'Branchial cleft', 'Testis NOS', 'Liver', 'Small intestine NOS', 'Central portion of breast', 'Submandibular gland', 'Female genital tract NOS', 'Islets of Langerhans', 'Vagina NOS', 'Ventricle NOS', 'Overlapping lesion of colon', 'Upper third of esophagus', 'Posterior wall of bladder', 'Anal canal', 'Heart', 'Lower-inner quadrant of breast', 'Short bones of lower limb and associated joints', 'Base of tongue NOS', 'Ill-defined sites within respiratory system', 'Prepuce', 'Carotid body', 'Hematopoietic system NOS', 'Cornea NOS', 'Anterior surface of epiglottis', 'Cortex of adrenal gland', 'Overlapping lesion of small intestine', 'Skin of lip NOS', 'Descending colon', 'Thymus', 'Lymph nodes of multiple regions', 'Vestibule of mouth', 'Cloacogenic zone', 'Upper gum', 'Overlapping lesions of oropharynx', 'Overlapping lesion of brain and central nervous system', 'Other specified parts of pancreas', 'Nipple', 'Mucosa of lower lip', 'Ventral surface of tongue NOS', 'Fundus of stomach', 'Lateral floor of mouth', 'Overlapping lesion of female genital organs', 'Long bones of upper limb scapula and associated joints', 'Overlapping lesion of penis', 'Superior wall of nasopharynx', 'Anterior mediastinum', 'Blood', 'Main bronchus', 'Urinary system NOS', 'Thorax NOS', 'Overlapping lesion of accessory sinuses', 'Glans penis', 'Exocervix', 'Duodenum', 'Mandible', 'Nasopharynx NOS', 'Pituitary gland', 'Olfactory nerve', 'Peripheral nerves and autonomic nervous system of head face and neck', 'Renal pelvis', 'Mucosa of upper lip', 'Overlapping lesion of other and unspecified parts of mouth', 'Peripheral nerves and autonomic nervous system of pelvis', 'Occipital lobe', 'Extrahepatic bile duct', 'Aortic body and other paraganglia', 'Scrotum NOS', 'Retina', 'Laryngeal cartilage', 'Upper limb NOS', 'Round ligament', 'Anus NOS', 'Border of tongue', 'Middle third of esophagus', 'Connective subcutaneous and other soft tissues of upper limb and shoulder', 'Overlapping lesion of lip oral cavity and pharynx', 'Corpus uteri', 'Overlapping lesion of corpus uteri', 'Lower lobe lung', 'Intrahepatic bile duct', 'Epididymis', 'Overlapping lesion of ill-defined sites', 'Peripheral nerves and autonomic nervous system of upper limb and shoulder', 'Hard palate', 'Hypopharynx NOS', 'Trachea', 'Male genital organs NOS', 'Skin of other and unspecified parts of face', 'Lacrimal gland', 'Palate NOS', 'Pylorus', 'Overlapping lesion of lung', 'Pelvic bones sacrum coccyx and associated joints', 'Sublingual gland', 'External lip NOS', 'Breast NOS', 'Labium minus', 'Lower-outer quadrant of breast', 'Myometrium', 'Spleen', 'Endocrine gland NOS', 'Ureteric orifice', 'Biliary tract NOS', 'Not Reported', 'Cervix uteri', 'Choroid', 'Conjunctiva', 'Cerebrum', 'Colon NOS', 'Adrenal gland NOS', 'Intra-abdominal lymph nodes', 'Overlapping lesion of urinary organs', 'Lateral wall of oropharynx', 'Overlapping lesion of eye and adnexa', 'Cheek mucosa', 'Overlapping lesion of cervix uteri', 'Fallopian tube', 'Overlapping lesion of stomach', 'Hypopharyngeal aspect of aryepiglottic fold', 'Mucosa of lip NOS', 'Retromolar area', 'Lymph node NOS', 'unknown primary site', 'Gum NOS', 'Meckel diverticulum', 'Uterus NOS', 'Thyroid gland', 'Overlapping lesion of connective subcutaneous and other soft tissues', 'Connective subcutaneous and other soft tissues NOS', 'Ethmoid sinus', 'Connective subcutaneous and other soft tissues of head face and neck', 'Overlapping lesion of palate', 'Body of penis', 'Craniopharyngeal duct', 'Eye NOS', 'Lower third of esophagus', 'Lip NOS', 'Acoustic nerve', 'Bladder neck', 'Upper-inner quadrant of breast', 'Pelvic lymph nodes', 'Hepatic flexure of colon', 'External lower lip', 'Cauda equina', 'Transverse colon', 'Cerebral meninges', 'Penis NOS', 'Skin of scalp and neck', 'Overlapping lesion of breast', 'Overlapping lesion of major salivary glands', 'Pleura NOS', 'Abdomen NOS', 'Ileum', 'Intestinal tract NOS', 'Parietal lobe', 'Trigone of bladder', 'Lymph nodes of head face and neck', 'Appendix', 'Upper lobe lung', 'Soft palate NOS', 'Tonsillar fossa', 'Esophagus NOS', 'Middle ear', 'Body of pancreas', 'Ciliary body', 'Ovary', 'Bone marrow', 'Commissure of lip', 'Thoracic esophagus', 'Overlapping lesion of hypopharynx', 'Ampulla of Vater', 'Overlapping lesion of tonsil', 'Upper-outer quadrant of breast', 'Cranial nerve NOS', 'Overlapping lesion of bones joints and articular cartilage of limbs', 'Overlapping lesion of pancreas', 'Urachus', 'Overlapping lesion of endocrine glands and related structures', 'Specified parts of peritoneum', 'Overlapping lesion of larynx', 'Supraglottis', 'Subglottis', 'Isthmus uteri', 'Bone NOS', 'Skin of lower limb and hip', 'Vallecula', 'Posterior wall of hypopharynx', 'Peripheral nerves and autonomic nervous system of trunk NOS', 'Tongue NOS', 'External upper lip', 'Skin of trunk', 'Lateral wall of bladder', 'Glottis', 'Peritoneum NOS', 'Broad ligament', 'Tail of pancreas', 'Overlapping lesion of esophagus', 'Cardia NOS', 'Long bones of lower limb and associated joints', 'Anterior wall of nasopharynx', 'Pelvis NOS', 'Other ill-defined sites', 'Abdominal esophagus', 'Skin of upper limb and shoulder', 'Connective subcutaneous and other soft tissues of pelvis', 'Overlapping lesion of brain', 'Greater curvature of stomach NOS', 'Short bones of upper limb and associated joints', 'Posterior wall of nasopharynx', 'Gallbladder', 'Lymph nodes of inguinal region or leg', 'Lower gum', 'Other specified parts of male genital organs', 'Head of pancreas', 'Overlapping lesion of bladder', 'Rectosigmoid junction', 'Spinal meninges', 'Connective subcutaneous and other soft tissues of lower limb and hip', 'Bone of limb NOS', 'Lesser curvature of stomach NOS', 'Cecum', 'unknown', 'Frontal sinus', 'Clitoris', 'Major salivary gland NOS', 'Accessory sinus NOS', 'Anterior floor of mouth', 'Overlapping lesion of male genital organs', 'Endocervix', 'Middle lobe lung', 'Overlapping lesion of peripheral nerves and autonomic nervous system', 'Lateral wall of nasopharynx', 'Orbit NOS', 'Pancreatic duct', 'Connective subcutaneous and other soft tissues of abdomen', 'Anterior wall of bladder', 'Intrathoracic lymph nodes', 'Lingual tonsil', 'Pineal gland', 'Tonsillar pillar', 'Spinal cord', 'Brain stem', 'Overlapping lesion of lip', 'Stomach NOS', 'Nasal cavity', 'Overlapping lesion of digestive system', 'Overlapping lesion of floor of mouth', '']",,Therapy
+Treatment Type,Treatment Type,TreatmentType,Text term that describes the kind of treatment administered.,False,,"['Surgery', 'Radiation Intensity-Modulated Radiotherapy', 'Ablation Radiosurgical', 'Ancillary Treatment', 'Chemoembolization', 'Radiation External Beam', 'Stem Cell Transplantation NOS', 'Stem Cell Transplantation Syngenic', 'Chemotherapy', 'Other', 'Radiation Combination', 'Bisphosphonate Therapy', 'External Beam Radiation', 'Hormone Therapy', 'Ablation Radiofrequency', 'Radiation Proton Beam', 'Chemoprotectant', 'Concurrent Chemoradiation', 'Pleurodesis', 'Stem Cell Transplantation Allogeneic', 'Ablation NOS', 'Antiseizure Treatment', 'I-131 Radiation Therapy', 'unknown', 'Stereotactic Radiosurgery', 'Embolization', 'Stem Cell Transplantation Non-Myeloablative', 'Pharmaceutical Therapy NOS', 'Targeted Molecular Therapy', 'Isolated Limb Perfusion (ILP)', 'Radioactive Iodine Therapy', 'Stem Cell Treatment', 'Not Reported', 'Stem Cell Transplantation Autologous', 'Brachytherapy High Dose', 'Radiation 3D Conformal', 'Ablation Microwave', 'Cryoablation', 'Internal Radiation', 'Organ Transplantation', 'Radiation Implants', 'Radiation Therapy NOS', 'Stem Cell Transplantation Double Autologous', 'Radiation 2D Conventional', 'Blinded Study Treatment unknown', 'Brachytherapy NOS', 'Ethanol Injection Ablation', 'Radiation Stereotactic/Gamma Knife/SRS', 'Ablation Ethanol Injection', 'Radiation Cyberknife', 'Radiation Radioisotope', 'Stem Cell Transplantation Haploidentical', 'Steroid Therapy', 'Radioembolization', 'Ablation Cryo', 'Radiation Systemic', 'Radiation Internal', 'Immunotherapy (Including Vaccines)', 'Radiosensitizing Agent', 'Brachytherapy Low Dose', '']",,Therapy
+HTAN Participant ID,HTAN Participant ID,HTANParticipantID,HTAN ID associated with a patient based on HTAN ID SOP (eg HTANx_yyy ),True,,,,Therapy
+Treatment Arm,Treatment Arm,TreatmentArm,Text term used to describe the treatment arm assigned to a patient at the time eligibility is determined.,False,,"['E4512', 'A081105', 'EA5142', '']",,Therapy
+Chemo Concurrent to Radiation,Chemo Concurrent to Radiation,ChemoConcurrenttoRadiation,The text term used to describe whether the patient was receiving chemotherapy concurrent to radiation.,False,,"['No', 'unknown', 'Not Reported', 'Yes', '']",,Therapy
+Reason Treatment Ended,Reason Treatment Ended,ReasonTreatmentEnded,The text term used to describe the reason a specific treatment or regimen ended.,False,,"['Course of Therapy Completed', 'Withdrawal by Subject', 'Other', 'Disease Progression', 'Death', 'Adverse Therapy Event', '']",,Therapy
+Therapeutic Agents,Therapeutic Agents,TherapeuticAgents,Text identification of the individual agent(s) used as part of a treatment regimen.,False,,,,Therapy
+Days to Treatment Start,Days to Treatment Start,DaystoTreatmentStart,Number of days between the date used for index and the date the treatment started.,False,,,,Therapy
+Days to Treatment End,Days to Treatment End,DaystoTreatmentEnd,Number of days between the date used for index and the date the treatment ended.,False,,,,Therapy
+Treatment Effect Indicator,Treatment Effect Indicator,TreatmentEffectIndicator,The text term used to indicate whether the treatment had an effect on the patient.,False,,"['No', 'unknown', 'Not Reported', 'Yes', '']",,Therapy
+Regimen or Line of Therapy,Regimen or Line of Therapy,RegimenorLineofTherapy,The text term used to describe the regimen or line of therapy.,False,,,,Therapy
+Treatment Effect,Treatment Effect,TreatmentEffect,The text term used to describe the pathologic effect a treatment(s) had on the tumor.,False,,"['Not Reported', 'No Necrosis', 'Incomplete Necrosis (Viable Tumor Present)', 'unknown', 'Complete Necrosis (No Viable Tumor)', '']",,Therapy
+Initial Disease Status,Initial Disease Status,InitialDiseaseStatus,The text term used to describe the status of the patient's malignancy when the treatment began.,False,,"['Not Reported', 'Initial Diagnosis', 'Residual Disease', 'Progressive Disease', 'Recurrent Disease', 'unknown', '']",,Therapy
+Treatment Dose,Treatment Dose,TreatmentDose,The numeric value used to describe the dose of an agent the patient received.,False,,,,Therapy
+Component,Component,Component,"Category of metadata (e.g. Diagnosis, Biospecimen, scRNA-seq Level 1, etc.); provide the same one for all items/rows.",True,,,,Therapy
+Treatment Dose Units,Treatment Dose Units,TreatmentDoseUnits,The text term used to describe the dose units of an agent the patient received.,False,,"['Gy', 'cGy', '']",,Therapy
+Treatment Outcome,Treatment Outcome,TreatmentOutcome,Text term that describes the patient's final outcome after the treatment was administered.,False,,"['Very Good Partial Response', 'Persistent Disease', 'Not Reported', 'Mixed Response', 'No Measurable Disease', 'Partial Response', 'Complete Response', 'Stable Disease', 'No Response', 'Progressive Disease', 'Treatment Ongoing', 'unknown', 'Treatment Stopped Due to Toxicity', '']",,Therapy
+Expression Units,Expression Units,ExpressionUnits,How quantities are corrected for gene length,True,,"['Other', 'TPM', 'FPKM', 'RPKM', 'NA', 'Counts']",,BulkRNA-seqLevel3
+HTAN Parent Data File ID,HTAN Parent Data File ID,HTANParentDataFileID,HTAN Data File Identifier indicating the file(s) from which these files were derived,True,,,,BulkRNA-seqLevel3
+Component,Component,Component,"Category of metadata (e.g. Diagnosis, Biospecimen, scRNA-seq Level 1, etc.); provide the same one for all items/rows.",True,,,,BulkRNA-seqLevel3
+File Format,File Format,fileFormat,"Format of a file (e.g. txt, csv, fastq, bam, etc.)",True,,"['am', 'locs', 'tif', 'hdf5', 'mtx', 'gff3', 'bed', 'sqlite', 'doc', 'm', 'R script', 'bigwig', 'svg', 'json', 'mpg', 'maf', 'excel', 'czi', 'tagAlign', 'bai', 'sdf', 'xml', 'png', 'wiggle', 'cloupe', 'txt', 'avi', 'DICOM', 'OME-TIFF', 'idx', 'zip', 'gtf', 'plink', 'html', 'sam', 'sif', 'powerpoint', 'fasta', 'dup', 'pzfx', 'cel', 'cell am', 'tiff', 'md', 'sav', 'dat', 'mex', 'tar', 'Sentrix descriptor file', 'bgzip', 'hic', 'jpg', 'gct', 'flagstat', 'tsv', 'tranches', 'bed broadPeak', 'rmd', 'abf', 'Python script', 'chp', 'svs', 'hyperlink', 'bpm', 'bcf', 'fastq', 'pdf', 'mzML', 'ab1', 'csv', 'RData', 'recal', 'raw', 'msf', 'sra', 'bed narrowPeak', 'fig', 'bam', 'idat', 'mov', 'bed gappedPeak', 'vcf', 'gzip', 'seg', '7z', 'bedgraph']",,BulkRNA-seqLevel3
+Fusion Gene Detected,Fusion Gene Detected,FusionGeneDetected,Was a fusion gene identified?,False,,"['Yes - Fusion Gene Detected', 'unknown', 'No', '']",,BulkRNA-seqLevel3
+Data Category,Data Category,DataCategory,Specific content type of the data file.,True,,"['Other', 'Exon Expression Quantification', 'Splice Junction Quantification', 'Gene Expression', 'Transcript Expression', 'Isoform Expression Quantification', 'Gene Expression Quantification']",,BulkRNA-seqLevel3
+Fusion Gene Identity,Fusion Gene Identity,FusionGeneIdentity,The gene symbols of fused genes.,False,,,,BulkRNA-seqLevel3
+Filename,Filename,filename,Name of a file ,True,,,,BulkRNA-seqLevel3
+HTAN Data File ID,HTAN Data File ID,HTANDataFileID,Self-identifier for this data file - HTAN ID of this file HTAN ID SOP (eg HTANx_yyy_zzz),True,,,,BulkRNA-seqLevel3
+Matrix Type,Matrix Type,MatrixType,Type of data stored in matrix.,True,,"['Scaled Counts', 'Raw Counts', 'Batch Corrected Counts', 'Normalized Counts']",,BulkRNA-seqLevel3
+Pseudo Alignment Used,Pseudo Alignment Used,PseudoAlignmentUsed,Pseudo aligners such as Kallisto or Salmon do not produce aligned reads BAM files. True indicates pseudoalignment was used.,True,,"['Yes - Pseudo Alignment Used', 'No']",,BulkRNA-seqLevel3
+Specify Other Fusion Gene,Specify Other Fusion Gene,SpecifyOtherFusionGene,"Specify fusion gene detected, if not in list",False,True,,"Fusion Gene Identity -is- ""Other Fusion Gene""",BulkRNA-seqLevel3
+Genomic Reference,Genomic Reference,GenomicReference,Exact version of the human genome reference used in the alignment of reads (e.g. https://www.gencodegenes.org/human/),False,True,,"Pseudo Alignment Used -is- ""Yes - Pseudo Alignment Used""",BulkRNA-seqLevel3
+Software and Version,Software and Version,SoftwareandVersion,Name of software used to generate expression values. String,False,True,,"Pseudo Alignment Used -is- ""Yes - Pseudo Alignment Used""",BulkRNA-seqLevel3
+Genomic Reference URL,Genomic Reference URL,GenomicReferenceURL,Link to human genome sequence (e.g. ftp://ftp.ebi.ac.uk/pub/databases/gencode/Gencode_human/release_34/GRCh38.primary_assembly.genome.fa.gz) [URL],False,True,,"Pseudo Alignment Used -is- ""Yes - Pseudo Alignment Used""",BulkRNA-seqLevel3
+Workflow Link,Workflow Link,WorkflowLink,Link to workflow or command. DockStore.org recommended. URL,False,True,,"Pseudo Alignment Used -is- ""Yes - Pseudo Alignment Used""",BulkRNA-seqLevel3
+Target Capture Kit,Target Capture Kit,TargetCaptureKit,"Description that can uniquely identify a target capture kit. Suggested value is a combination of vendor, kit name, and kit version.",True,,"['Foundation Medicine T5a Panel - 322 Genes', 'Nextera DNA Exome', 'Ion AmpliSeq Cancer Hotspot Panel v2', 'TruSeq Amplicon Cancer Panel', 'Not Applicable', 'Custom PGDX SureSelect CancerSelect VAREPOP-APOLLO Panel - 203 Genes', 'Ion AmpliSeq Comprehensive Cancer Panel', 'Nextera Rapid Capture Exome v1.2', 'Custom MSK IMPACT Panel - 468 Genes', 'Custom SureSelect CGCI-BLGSP Panel - 4.6 Mb', 'Custom Solid Tumor GENIE-VICC Panel - 34 Genes', 'SeqCap EZ Human Exome v2.0', 'SureSelect Human All Exon v5 + UTR', 'TruSeq RNA Exome', 'Custom HaloPlex DLBCL Panel - 370 Genes', 'Custom SureSelect Human All Exon v1.1 Plus 3 Boosters', 'Custom Ion AmpliSeq Hotspot GENIE-MOSC3 Augmented Panel - 74 Genes', 'Custom Twist Broad PanCancer Panel - 396 Genes', 'unknown', 'Custom MSK IMPACT Panel - 341 Genes', 'Custom GENIE-DFCI Oncopanel - 300 Genes', 'Custom SeqCap EZ HGSC VCRome v2.1 ER Augmented v2', 'Custom MSK IMPACT Panel - 410 Genes', 'Custom GENIE-DFCI Oncopanel - 447 Genes', 'Custom SureSelect GENIE-UHN Panel - 555 Genes', 'Custom SureSelect CGCI-HTMCP-CC KMT2D And Hotspot Panel - 37.0 Kb', 'Custom Twist Broad Exome v1.0 - 35.0 Mb', 'Custom SureSelect CGCI-HTMCP-CC Panel - 19.7 Mb', 'Custom PGDX SureSelect CancerSelect VAREPOP-APOLLO Panel - 88 Genes', 'SureSelect Human All Exon v4', 'Custom Large Construct Capture TARGET-OS Panel - 8 Genes', 'SeqCap EZ Human Exome v3.0', 'SureSelect Human All Exon v5', 'TruSeq Exome Enrichment - 62 Mb', 'xGen Exome Research Panel v1.0', 'Custom GENIE-DFCI OncoPanel - 275 Genes', 'Custom SeqCap EZ TARGET-OS Panel - 7.0 Mb', 'Custom SureSelect TARGET-AML_NBL_WT Panel - 2.8 Mb', 'Custom Myeloid GENIE-VICC Panel - 37 Genes', 'SureSelect Human All Exon v3', 'Custom SeqCap EZ HGSC VCRome v2.1 ER Augmented v1', 'Custom Targets File Provided', 'Custom Personalis ACEcp VAREPOP-APOLLO Panel v2', 'Custom AmpliSeq Cancer Hotspot GENIE-MDA Augmented Panel v1 - 46 Genes', 'Foundation Medicine T7 Panel - 429 Genes', 'SeqCap EZ HGSC VCRome v2.1', 'TruSight Myeloid Sequencing Panel']",,BulkWESLevel1
+Flow Cell Barcode,Flow Cell Barcode,FlowCellBarcode,Flow cell barcode. Wrong or missing information may affect analysis results. String,False,,,,BulkWESLevel1
+Fragment Maximum Length,Fragment Maximum Length,FragmentMaximumLength,"Maximum length of the sequenced fragments (e.g., as predicted by Agilent Bioanalyzer). Integer",False,,,,BulkWESLevel1
+Adapter Name,Adapter Name,AdapterName,Name of the sequencing adapter. String,False,,,,BulkWESLevel1
+Read Length,Read Length,ReadLength,"The length of the sequencing reads. Can be integer, null",True,,,,BulkWESLevel1
+Sequencing Batch ID,Sequencing Batch ID,SequencingBatchID,Links samples to a specific local sequencer run. Can be string or 'null',True,,,,BulkWESLevel1
+Base Caller Version,Base Caller Version,BaseCallerVersion,Version of the base caller. String,False,,,,BulkWESLevel1
+Library Preparation Days from Index,Library Preparation Days from Index,LibraryPreparationDaysfromIndex,Number of days between sample for assay was received in lab and the libraries were prepared for sequencing [number],False,,,,BulkWESLevel1
+HTAN Parent Biospecimen ID,HTAN Parent Biospecimen ID,HTANParentBiospecimenID,HTAN Biospecimen Identifier (eg HTANx_yyy_zzz) indicating the biospecimen(s) from which these files were derived; multiple parent biospecimen should be comma-separated,True,,,,BulkWESLevel1
+Library Preparation Kit Name,Library Preparation Kit Name,LibraryPreparationKitName,Name of Library Preparation Kit. String,True,,,,BulkWESLevel1
+Fragment Mean Length,Fragment Mean Length,FragmentMeanLength,"Mean length of the sequenced fragments (e.g., as predicted by Agilent Bioanalyzer). Number",False,,,,BulkWESLevel1
+Multiplex Barcode,Multiplex Barcode,MultiplexBarcode,The barcode/index sequence used. Wrong or missing information may affect analysis results. String,False,,,,BulkWESLevel1
+Library Selection Method,Library Selection Method,LibrarySelectionMethod,How RNA molecules are isolated.,True,,"['Poly-T Enrichment', 'Hybrid Selection', 'PCR', 'miRNA Size Fractionation', 'Affinity Enrichment', 'Other', 'rRNA Depletion', 'Random']",,BulkWESLevel1
+Filename,Filename,filename,Name of a file ,True,,,,BulkWESLevel1
+Component,Component,Component,"Category of metadata (e.g. Diagnosis, Biospecimen, scRNA-seq Level 1, etc.); provide the same one for all items/rows.",True,,,,BulkWESLevel1
+Library Layout,Library Layout,LibraryLayout,Sequencing read type,True,,"['Paired End', 'Single Read']",,BulkWESLevel1
+Adapter Sequence,Adapter Sequence,AdapterSequence,Base sequence of the sequencing adapter. String,False,,,,BulkWESLevel1
+Target Depth,Target Depth,TargetDepth,The targeted read depth prior to sequencing. Integer,False,,,,BulkWESLevel1
+Fragment Minimum Length,Fragment Minimum Length,FragmentMinimumLength,"Minimum length of the sequenced fragments (e.g., as predicted by Agilent Bioanalyzer). Integer",False,,,,BulkWESLevel1
+Library Preparation Kit Version,Library Preparation Kit Version,LibraryPreparationKitVersion,Version of Library Preparation Kit. String,True,,,,BulkWESLevel1
+Read Indicator,Read Indicator,ReadIndicator,Indicate if this is Read 1 (R1) or Read 2 (R2),True,,"['R1&R2', 'R2', 'R1']",,BulkWESLevel1
+Fragment Standard Deviation Length,Fragment Standard Deviation Length,FragmentStandardDeviationLength,"Standard deviation of the sequenced fragments length (e.g., as predicted by Agilent Bioanalyzer). Number",False,,,,BulkWESLevel1
+HTAN Data File ID,HTAN Data File ID,HTANDataFileID,Self-identifier for this data file - HTAN ID of this file HTAN ID SOP (eg HTANx_yyy_zzz),True,,,,BulkWESLevel1
+Library Preparation Kit Vendor,Library Preparation Kit Vendor,LibraryPreparationKitVendor,Vendor of Library Preparation Kit. String,True,,,,BulkWESLevel1
+Size Selection Range,Size Selection Range,SizeSelectionRange,Range of size selection. String,False,,,,BulkWESLevel1
+To Trim Adapter Sequence,To Trim Adapter Sequence,ToTrimAdapterSequence,Does the user suggest adapter trimming?,False,,"['No', 'Yes - Trim Adapter Sequence', '']",,BulkWESLevel1
+Lane Number,Lane Number,LaneNumber,"The basic machine unit for sequencing. For Illumina machines, this reflects the physical lane number. Wrong or missing information may affect analysis results. Integer",False,,,,BulkWESLevel1
+Sequencing Platform,Sequencing Platform,SequencingPlatform,A platform is an object aggregate that is the set of instruments and software needed to perform a process [OBI_0000050]. Specific model of the sequencing instrument.,True,,"['Illumina NovaSeq 6000', 'Ion Torrent Proton', 'Illumina MiSeq', 'Illumina Genome Analyzer II', 'Not Reported', 'Illumina HiSeq 2000', 'Illumina Next Seq 550', 'Illumina HiSeq 2500', 'Complete Genomics', 'NovaSeq 6000', 'unknown', 'Illumina Genome Analyzer IIx', 'Other', 'NovaSeqS4', 'Illumina Next Seq 500', 'Illumina NextSeq', 'Illumina HiSeq X Ten', 'Ion Torrent S5', 'Ion Torrent PGM', '454 GS FLX Titanium', 'PacBio RS', 'AB SOLiD 3', 'Illumina Next Seq 2500', 'Illumina HiSeq X Five', 'AB SOLiD 4 AB SOLiD 2', 'Illumina HiSeq 4000']",,BulkWESLevel1
+File Format,File Format,fileFormat,"Format of a file (e.g. txt, csv, fastq, bam, etc.)",True,,"['doc', 'bpm', 'maf', 'svg', 'fig', 'gff3', 'ab1', 'gct', 'mov', 'cel', 'RData', 'vcf', 'md', 'json', 'xml', 'mpg', 'tiff', 'rmd', 'gzip', 'mtx', 'cell am', 'sif', 'tar', 'idat', 'bed narrowPeak', 'bai', 'bigwig', 'DICOM', 'hdf5', 'hic', 'plink', 'sra', 'cloupe', 'R script', 'flagstat', '7z', 'recal', 'fastq', 'dat', 'bedgraph', 'bam', 'Python script', 'sqlite', 'tagAlign', 'sam', 'bed gappedPeak', 'jpg', 'am', 'csv', 'fasta', 'msf', 'excel', 'tif', 'bed', 'czi', 'tranches', 'zip', 'm', 'mzML', 'bcf', 'svs', 'avi', 'seg', 'bgzip', 'txt', 'wiggle', 'dup', 'Sentrix descriptor file', 'pdf', 'tsv', 'raw', 'OME-TIFF', 'abf', 'bed broadPeak', 'mex', 'hyperlink', 'html', 'idx', 'locs', 'png', 'sav', 'gtf', 'sdf', 'pzfx', 'chp', 'powerpoint']",,BulkWESLevel1
+Base Caller Name,Base Caller Name,BaseCallerName,Name of the base caller. String,False,,,,BulkWESLevel1
+Checksum,Checksum,Checksum,MD5 checksum of the BAM file,True,,,,ScRNA-seqLevel2
+Workflow Link,Workflow Link,WorkflowLink,Link to workflow or command. DockStore.org recommended. URL,True,,,,ScRNA-seqLevel2
+Genomic Reference URL,Genomic Reference URL,GenomicReferenceURL,Link to human genome sequence (e.g. ftp://ftp.ebi.ac.uk/pub/databases/gencode/Gencode_human/release_34/GRCh38.primary_assembly.genome.fa.gz) [URL],True,,,,ScRNA-seqLevel2
+Genomic Reference,Genomic Reference,GenomicReference,Exact version of the human genome reference used in the alignment of reads (e.g. https://www.gencodegenes.org/human/),True,,,,ScRNA-seqLevel2
+HTAN Parent Data File ID,HTAN Parent Data File ID,HTANParentDataFileID,HTAN Data File Identifier indicating the file(s) from which these files were derived,True,,,,ScRNA-seqLevel2
+scRNAseq Workflow Parameters Description,scRNAseq Workflow Parameters Description,ScRNAseqWorkflowParametersDescription,"Parameters used to run the workflow. scRNA-seq level 3: e.g. Normalization and log transformation, ran empty drops or doublet detection, used filter on # genes/cell, etc. scRNA-seq Level 4: dimensionality reduction with PCA and 50 components, nearest-neighbor graph with k = 20 and Leiden clustering with resolution = 1, UMAP visualization using 50 PCA components, marker genes used to annotate cell types, information about droplet matrix (all barcodes) to cell matrix (only informative barcodes representing real cells) conversion",True,,,,ScRNA-seqLevel2
+Applied Hard Trimming,Applied Hard Trimming,AppliedHardTrimming,TBD,True,,"['No', 'Yes - Applied Hard Trimming']",,ScRNA-seqLevel2
+Component,Component,Component,"Category of metadata (e.g. Diagnosis, Biospecimen, scRNA-seq Level 1, etc.); provide the same one for all items/rows.",True,,,,ScRNA-seqLevel2
+Workflow Version,Workflow Version,WorkflowVersion,Major version of the workflow (e.g. Cell Ranger v3.1),True,,,,ScRNA-seqLevel2
+scRNAseq Workflow Type,scRNAseq Workflow Type,ScRNAseqWorkflowType,Generic name for the workflow used to analyze a data set.,True,,"['DEXSeq', 'Cufflinks', 'SEQC', 'Other', 'STARsolo', 'HTSeq - FPKM', 'HCA Optimus', 'dropEST', 'CellRanger', 'Differentiation trajectory analysis', 'Cell annotation']",,ScRNA-seqLevel2
+Genome Annotation URL,Genome Annotation URL,GenomeAnnotationURL,Link to the human genome annotation (GTF) file (e.g. ftp://ftp.ebi.ac.uk/pub/databases/gencode/Gencode_human/release_34/gencode.v34.annotation.gtf.gz),True,,,,ScRNA-seqLevel2
+UMI Tag,UMI Tag,UMITag,"SAM tag for UMI field; please provide a valid UB, UMI",True,,,,ScRNA-seqLevel2
+Cell Barcode Tag,Cell Barcode Tag,CellBarcodeTag,SAM tag for cell barcode field; please provide a valid cell barcode tag,True,,,,ScRNA-seqLevel2
+File Format,File Format,fileFormat,"Format of a file (e.g. txt, csv, fastq, bam, etc.)",True,,"['bed narrowPeak', '7z', 'Sentrix descriptor file', 'OME-TIFF', 'bpm', 'dat', 'ab1', 'mpg', 'mzML', 'tiff', 'bed', 'bam', 'vcf', 'bedgraph', 'pdf', 'fasta', 'powerpoint', 'cel', 'locs', 'msf', 'rmd', 'recal', 'Python script', 'gtf', 'sif', 'sqlite', 'hic', 'tar', 'tranches', 'abf', 'html', 'cell am', 'wiggle', 'zip', 'md', 'tif', 'idx', 'jpg', 'svg', 'bed broadPeak', 'bigwig', 'mtx', 'm', 'png', 'am', 'gff3', 'fig', 'bai', 'xml', 'fastq', 'bcf', 'excel', 'sam', 'mov', 'tagAlign', 'RData', 'gct', 'hyperlink', 'dup', 'hdf5', 'txt', 'pzfx', 'svs', 'bgzip', 'bed gappedPeak', 'plink', 'doc', 'tsv', 'sdf', 'avi', 'idat', 'chp', 'csv', 'json', 'sav', 'gzip', 'mex', 'cloupe', 'R script', 'maf', 'czi', 'sra', 'seg', 'flagstat', 'raw', 'DICOM']",,ScRNA-seqLevel2
+Filename,Filename,filename,Name of a file ,True,,,,ScRNA-seqLevel2
+HTAN Data File ID,HTAN Data File ID,HTANDataFileID,Self-identifier for this data file - HTAN ID of this file HTAN ID SOP (eg HTANx_yyy_zzz),True,,,,ScRNA-seqLevel2
+Whitelist Cell Barcode File Link,Whitelist Cell Barcode File Link,WhitelistCellBarcodeFileLink,Link to file listing all possible cell barcodes. URL,True,,,,ScRNA-seqLevel2
+Aligned Read Length,Aligned Read Length,AlignedReadLength,Read length used for alignment if hard trimming was applied,False,True,,"Applied Hard Trimming -is- ""Yes - Applied Hard Trimming""",ScRNA-seqLevel2
+Comorbidity Method of Diagnosis,Comorbidity Method of Diagnosis,ComorbidityMethodofDiagnosis,The text term used to describe the method used to diagnose the patient's comorbidity disease.,False,,"['Histology', 'Radiology', 'unknown', 'Pathology', 'Not Reported', '']",,FollowUp
+Cause of Response,Cause of Response,CauseofResponse,The text term used to describe the suspected cause or reason for the patient disease response.,False,,,,FollowUp
+Weight,Weight,Weight,The weight of the patient measured in kilograms.,False,,,,FollowUp
+Nadir CD4 Count,Nadir CD4 Count,NadirCD4Count,Numeric value that represents the lowest point to which the CD4 count has dropped (nadir).,False,,,,FollowUp
+FEV1 FVC Post Bronch Percent,FEV1 FVC Post Bronch Percent,FEV1FVCPostBronchPercent,Percentage value to represent result of Forced Expiratory Volume in 1 second (FEV1) divided by the Forced Vital Capacity (FVC) post-bronchodilator.,False,,,,FollowUp
+Component,Component,Component,"Category of metadata (e.g. Diagnosis, Biospecimen, scRNA-seq Level 1, etc.); provide the same one for all items/rows.",True,,,,FollowUp
+Barretts Esophagus Goblet Cells Present,Barretts Esophagus Goblet Cells Present,BarrettsEsophagusGobletCellsPresent,TBD,False,,,,FollowUp
+Days to Adverse Event,Days to Adverse Event,DaystoAdverseEvent,Number of days between the date used for index and the date of the patient's adverse event.,False,,,,FollowUp
+Recist Targeted Regions Sum,Recist Targeted Regions Sum,RecistTargetedRegionsSum,"Numeric value that represents the sum of baseline target lesions, as described by the Response Evaluation Criteria in Solid Tumours (RECIST) criteria.",False,,,,FollowUp
+Scan Tracer Used,Scan Tracer Used,ScanTracerUsed,The text term used to describe the type of tracer used during the imaging or scan of the patient.,False,,"['Acetate', 'PSMA', 'Sodium Fluoride', 'Choline', 'Axumin', '']",,FollowUp
+Disease Response,Disease Response,DiseaseResponse,Code assigned to describe the patient's response or outcome to the disease.,False,,"['DU-Disease Unchanged', 'NPB-No Palliative Benefit', 'TE-Too Early', 'NR-No Response', 'CR-Complete Response', 'PA-Palliative Therapy', 'SPD-Surgical Progression', 'Not Reported', 'AJ-Adjuvant Therapy', 'Non-CR/Non-PD-Non-CR/Non-PD', 'SD-Stable Disease', 'BED-Biochemical Evidence of Disease', 'TF-Tumor Free', 'IMR-Immunoresponse', 'MR-Minimal/Marginal response', 'RD-Responsive Disease', 'unknown', 'PD-Progressive Disease', 'VGPR-Very Good Partial Response', 'WT-With Tumor', 'PPD-Pseudoprogression', 'CPD-Clinical Progression', 'IPD-Immunoprogression', 'RPD-Radiographic Progressive Disease', 'RP-Response', 'PR-Partial Response', 'CRU-Complete Response Unconfirmed', 'sCR-Stringent Complete Response', 'PB-Palliative Benefit', 'PSR-Pseudoresponse', 'PLD-Persistent Locoregional Disease', 'PDM-Persistent Distant Metastasis', 'MX-Mixed Response', '']",,FollowUp
+Imaging Type,Imaging Type,ImagingType,The text term used to describe the type of imaging or scan performed on the patient.,False,,"['PET', 'CT Scan', 'MRI', '99mTc Bone Scintigraphy', '']",,FollowUp
+Height,Height,Height,The height of the patient in centimeters.,False,,,,FollowUp
+Evidence of Recurrence Type,Evidence of Recurrence Type,EvidenceofRecurrenceType,The text term used to describe the type of evidence used to determine whether the patient's disease recurred,False,,"['Convincing Image Source', 'Positive Biomarkers', 'Biopsy with Histologic Confirmation', '']",,FollowUp
+Adverse Event,Adverse Event,AdverseEvent,Text that represents the Common Terminology Criteria for Adverse Events low level term name for an adverse event.,False,,"['Blood Gonadotrophin Abnormal', 'Duodenal Obstruction', 'Presyncope', 'Meningismus', 'Hypokalemia', 'Facial Pain', 'Bronchial Stricture', 'Intraoperative Neurological Injury', 'Pharyngeal Hemorrhage', 'Fecal Incontinence', 'Pleural Hemorrhage', 'Bronchial Infection', 'Lower Gastrointestinal Hemorrhage', 'Cecal Infection', 'Pelvic Floor Muscle Weakness', 'Uterine Anastomotic Leak', 'Dyspepsia', 'Pelvic Infection', 'Proctitis', 'Pleural Effusion', 'Pleural Infection', 'Thoracic and Mediastinal Disorders Other', 'Tumor Pain', 'Virilization', 'Atrioventricular Block First Degree', 'Night Blindness', 'Skin Induration', 'Esophageal Ulcer', 'Leukoencephalopathy', 'Head Soft Tissue Necrosis', 'Hepatobiliary Disorders Other', 'Nipple Deformity', 'Vestibular Disorder', 'Bladder Spasm', 'Urethral Infection', 'Corneal Infection', 'Pericardial Effusion', 'Muscle Weakness Lower Limb', 'Bladder Perforation', 'Pulmonary Fistula', 'Respiratory', 'Gallbladder Pain', 'Hydrocephalus', 'Cardiac Troponin T Increased', 'Tooth Infection', 'Abdominal Infection', 'Endocrine Disorders Other', 'Ileal Stenosis', 'Obesity', 'Pancreas Infection', 'Ejection Fraction Decreased', 'Arachnoiditis', 'Gum Infection', 'Gingival Pain', 'Cardiac Troponin I Increased', 'Scrotal Infection', 'Vasovagal Reaction', 'Spermatic Cord Hemorrhage', 'Visceral Arterial Ischemia', 'Colonic Hemorrhage', 'Agitation', 'Left Ventricular Systolic Dysfunction', 'Gait Disturbance', 'Joint Range of Motion Decreased Cervical Spine', 'Aortic Valve Disease', 'Urinary Fistula', 'Intraoperative Head and Neck Injury', 'Catheter Related Infection', 'Aortic Injury', 'Febrile Neutropenia', 'Diarrhea', 'Typhlitis', 'Cholesterol High', 'Laryngeal Edema', 'Urinary Incontinence', 'Skin and Subcutaneous Tissue Disorders Other', 'Ileus', 'Alkalosis', 'Pain of Skin', 'Iron Overload', 'Upper Gastrointestinal Hemorrhage', 'Injury to Carotid Artery', 'Gynecomastia', 'Esophageal Anastomotic Leak', 'Renal Colic', 'Hyperhidrosis', 'Tracheal Mucositis', 'Fetal Death', 'Flatulence', 'Thromboembolic Event', 'Otitis Media', 'Skin Infection', 'Restlessness', 'Palmar-Plantar Erythrodysesthesia Syndrome', 'Reversible Posterior Leukoencephalopathy Syndrome', 'Productive Cough', 'Breast Atrophy', 'Anxiety', 'Periodontal Disease', 'Tracheostomy Site Bleeding', 'Gastric Stenosis', 'Mitral Valve Disease', 'Injury', 'Azoospermia', 'Salivary Gland Infection', 'Ankle Fracture', 'Glaucoma', 'Renal and Urinary Disorders Other', 'Rash Maculo-Papular', 'Small Intestinal Obstruction', 'Joint Effusion', 'Anal Hemorrhage', 'Intestinal Stoma Obstruction', 'Encephalomyelitis Infection', 'Esophageal Hemorrhage', 'Hyperkalemia', 'Intraoperative Urinary Injury', 'Hypermagnesemia', 'Corneal Ulcer', 'Sinus Disorder', 'Rectal Perforation', 'Intra-Abdominal Hemorrhage', 'Pancreatic Necrosis', 'Growth Suppression', 'Gastrointestinal Pain', 'Hypophosphatemia', 'Pelvic Pain', 'Joint Infection', 'Cerebrospinal Fluid Leakage', 'Small Intestinal Anastomotic Leak', 'Flu Like Symptoms', 'Pharyngeal Fistula', 'Wound Complication', 'Extrapyramidal Disorder', 'Alkaline Phosphatase Increased', 'Chest Wall Pain', 'Muscle Weakness Right-Sided', 'Chylothorax', 'Hemorrhoids', 'Eyelid Function Disorder', 'Feminization Acquired', 'Insomnia', 'Fracture', 'Scleral Disorder', 'Alanine Aminotransferase Increased', 'Pulmonary Edema', 'Periorbital Infection', 'Bladder Anastomotic Leak', 'Autoimmune Disorder', 'Hemoglobin Increased', 'Pneumothorax', 'Proteinuria', 'Hematoma', 'Sudden Death NOS', 'Anorgasmia', 'Pharyngeal Stenosis', 'Anemia', 'Mania', 'Rectal Mucositis', 'Muscle Weakness Trunk', 'Postoperative Hemorrhage', 'Rectal Ulcer', 'Prostatic Hemorrhage', 'Restrictive Cardiomyopathy', 'Depression', 'Laryngeal Fistula', 'Scrotal Pain', 'Muscle Weakness Left-Sided', 'Bronchopulmonary Hemorrhage', 'Large Intestinal Anastomotic Leak', 'Neutrophil Count Decreased', 'Pancreatitis', 'Skin Hyperpigmentation', 'Forced Expiratory Volume Decreased', 'Intraoperative Reproductive Tract Injury', 'Pharyngolaryngeal Pain', 'Lymph Leakage', 'Breast Infection', 'Stomal Ulcer', 'Conjunctivitis Infective', 'Cystitis Noninfective', 'Skin Hypopigmentation', 'Bronchial Fistula', 'Amnesia', 'Colonic Fistula', 'Papulopustular Rash', 'Esophageal Perforation', 'Appendicitis', 'Papilledema', 'External Ear Inflammation', 'Lactation Disorder', 'Pneumonitis', 'Small Intestine Ulcer', 'Postoperative Thoracic Procedure Complication', 'Ascites', 'Dry Eye', 'Gastrointestinal Fistula', 'Edema Trunk', 'Menorrhagia', 'Spleen Disorder', 'Abdominal Soft Tissue Necrosis', 'Ovarian Infection', 'Hemolytic Uremic Syndrome', 'Nail Discoloration', 'Bone Pain', 'Generalized Muscle Weakness', 'Gastric Ulcer', 'Urticaria', 'Vaginal Anastomotic Leak', 'Familial and Genetic Disorders Other', 'Esophageal Stenosis', 'Irregular Menstruation', 'Musculoskeletal and Connective Tissue Disorders Other', 'Arterial Injury', 'Fibrosis Deep Connective Tissue', 'Ovarian Hemorrhage', 'Encephalopathy', 'Ischemia Cerebrovascular', 'Hyperglycemia', 'Osteonecrosis of Jaw', 'Epistaxis', 'Intraoperative Hepatobiliary Injury', 'Paresthesia', 'Lung Infection', 'Gallbladder Perforation', 'Anorectal Infection', 'Hypohidrosis', 'Jejunal Fistula', 'Menopause', 'Laryngeal Inflammation', 'Pain', 'Delirium', 'Hypertriglyceridemia', 'Photophobia', 'Vagus Nerve Disorder', 'Keratitis', 'Arthralgia', 'Alopecia', 'Neuralgia', 'Carbon Monoxide Diffusing Capacity Decreased', 'Stenosis of Gastrointestinal Stoma', 'Cardiac Disorders Other', 'Colonic Obstruction', 'Ovarian Rupture', 'Pancreatic Enzymes Decreased', 'Atelectasis', 'Hypothyroidism', 'Depressed Level of Consciousness', 'Aspartate Aminotransferase Increased', 'Hypomagnesemia', 'Venous Injury', 'Recurrent Laryngeal Nerve Palsy', 'Scalp Pain', 'Vaginal Stricture', 'Pulmonary Fibrosis', 'Hepatic Infection', 'Fetal Growth Retardation', 'Myocarditis', 'Pregnancy', 'Small Intestinal Stenosis', 'Treatment Related Secondary Malignancy', 'Mobitz (Type) II Atrioventricular Block', 'Avascular Necrosis', 'White Blood Cell Decreased', 'Palpitations', 'Laryngeal Mucositis', 'Gallbladder Obstruction', 'Asystole', 'Urinary Retention', 'Tracheitis', 'Respiratory Failure', 'Poisoning and Procedural Complications Other', 'Pulmonary Hypertension', 'Esophageal Pain', 'Dry Skin', 'Salivary Gland Fistula', 'Flank Pain', 'Esophageal Necrosis', 'Tracheal Obstruction', 'Muscle Weakness Upper Limb', 'Salivary Duct Inflammation', 'Supraventricular Tachycardia', 'Cranial Nerve Infection', 'Stridor', 'Pharyngeal Necrosis', 'Aspiration', 'Hyperthyroidism', 'Localized Edema', 'Body Odor', 'Alcohol Intolerance', 'Enterocolitis Infectious', 'Vas Deferens Anastomotic Leak', 'Breast Pain', 'Intraoperative Hemorrhage', 'Chills', 'Dental Caries', 'Gastrointestinal Anastomotic Leak', 'Endophthalmitis', 'Spasticity', 'Esophageal Fistula', 'Vascular Access Complication', 'Voice Alteration', 'Oral Pain', 'Jejunal Hemorrhage', 'Superficial Soft Tissue Fibrosis', 'Hemorrhoidal Hemorrhage', 'Oculomotor Nerve Disorder', 'Hypercalcemia', 'Retinal Detachment', 'Unintended Pregnancy', 'Psychiatric Disorders Other', 'Biliary Tract Infection', 'Ileal Ulcer', 'Urine Output Decreased', 'Fallopian Tube Obstruction', 'Kidney Anastomotic Leak', 'Death NOS', 'Fallopian Tube Stenosis', 'Pancreatic Anastomotic Leak', 'Spermatic Cord Anastomotic Leak', 'Somnolence', 'Rectal Anastomotic Leak', 'Rectal Obstruction', 'Oral Dysesthesia', 'Superficial Thrombophlebitis', 'Brachial Plexopathy', 'Erythema Multiforme', 'Leukocytosis', 'Neck Soft Tissue Necrosis', 'Right Ventricular Dysfunction', 'Urinary Urgency', 'Ear Pain', 'Dysmenorrhea', 'Intestinal Stoma Site Bleeding', 'Hypocalcemia', 'Hepatitis Viral', 'Urostomy Stenosis', 'Anal Stenosis', 'Dehydration', 'Acute Coronary Syndrome', 'Cecal Hemorrhage', 'Conduction Disorder', 'Dyspnea', 'Vaginal Pain', 'Middle Ear Inflammation', 'Ileal Perforation', 'Otitis Externa', 'Duodenal Perforation', 'Eye Infection', 'Immune System Disorders Other', 'Obstruction Gastric', 'Perforation Bile Duct', 'Laryngeal Obstruction', 'Sinus Pain', 'Uterine Infection', 'Acute Kidney Injury', 'Wheezing', 'Infusion Site Extravasation', 'Confusion', 'Device Related Infection', 'Hirsutism', 'Vaginal Infection', 'Hoarseness', 'Gastric Necrosis', 'Colitis', 'Psychosis', 'Joint Range of Motion Decreased Lumbar Spine', 'Phlebitis Infective', 'Hip Fracture', 'Tremor', 'Ventricular Fibrillation', 'Pulmonary Valve Disease', 'Ventricular Tachycardia', 'Portal Vein Thrombosis', 'Pyramidal Tract Syndrome', 'Apnea', 'Small Intestinal Perforation', 'Retinal Tear', 'Urostomy Obstruction', 'Cheilitis', 'Retinal Vascular Disorder', 'Chest Pain Cardiac', 'Tricuspid Valve Disease', 'Mediastinal Hemorrhage', 'Urostomy Leak', 'Prostatic Pain', 'Fat Atrophy', 'Injury to Inferior Vena Cava', 'Nystagmus', 'Intraoperative Musculoskeletal Injury', 'Rash Acneiform', 'Vaginal Hemorrhage', 'Seizure', 'Intraoperative Breast Injury', 'Bone Infection', 'Sinus Bradycardia', 'Radiation Recall Reaction (Dermatologic)', 'Renal Hemorrhage', 'Wound Dehiscence', 'Hematosalpinx', 'Anaphylaxis', 'Glucose Intolerance', 'Memory Impairment', 'Ataxia', 'Dermatitis Radiation', 'Lipase Increased', 'Uterine Pain', 'GGT Increased', 'Puerperium and Perinatal Conditions Other', 'Hot Flashes', 'Small Intestine Infection', 'Pharyngeal Mucositis', 'Vomiting', 'Bullous Dermatitis', 'Joint Range of Motion Decreased', 'Uterine Hemorrhage', 'Hyperparathyroidism', 'Reproductive System and Breast Disorders Other', 'Movements Involuntary', 'Tumor Lysis Syndrome', 'Scoliosis', 'Akathisia', 'Edema Cerebral', 'Sinus Tachycardia', 'Intraoperative Respiratory Injury', 'Cough', 'Toxic Epidermal Necrolysis', 'Fall', 'Kidney Infection', 'Sore Throat', 'Gastric Hemorrhage', 'CD4 Lymphocytes Decreased', 'Malaise', 'Paroxysmal Atrial Tachycardia', 'Spermatic Cord Obstruction', 'Gastrointestinal Stoma Necrosis', 'Neck Edema', 'Hypernatremia', 'Biliary Fistula', 'Ovulation Pain', 'Pancreatic Duct Stenosis', 'Laryngopharyngeal Dysesthesia', 'Pleuritic Pain', 'Gastric Perforation', 'Extraocular Muscle Paresis', 'Atrioventricular Block Complete', 'Myositis', 'Suicide Attempt', 'Tracheal Hemorrhage', 'Lymphocele', 'Prostatic Obstruction', 'Pharyngeal Anastomotic Leak', 'Colonic Ulcer', 'CPK Increased', 'Atrial Flutter', 'Dysphagia', 'Tinnitus', 'Urinary Frequency', 'Injury to Jugular Vein', 'Constrictive Pericarditis', 'Chronic Kidney Disease', 'Anal Fistula', 'Syncope', 'Infections and Infestations Other', 'Investigations Other', 'Hemolysis', 'Watering Eyes', 'Lethargy', 'Cushingoid', 'Toothache', 'Meningitis', 'Abdominal Distension', 'Gallbladder Infection', 'Serum Amylase Increased', 'Bloating', 'Pain in Extremity', 'Tooth Development Disorder', 'Penile Pain', 'Flashing Lights', 'Enterovesical Fistula', 'Duodenal Infection', 'Testicular Disorder', 'Dysesthesia', 'Anal Mucositis', 'Premature Delivery', 'Urinary Tract Infection', 'Delayed Puberty', 'Purpura', 'Dizziness', 'Stoma Site Infection', 'Kyphosis', 'Wound Infection', 'Adrenal Insufficiency', 'Tracheal Fistula', 'Nervous System Disorders Other', 'Hypoxia', 'Delayed Orgasm', 'Endocarditis Infective', 'Injection Site Reaction', 'Uterine Fistula', 'Peritoneal Necrosis', 'Lip Infection', 'Hypotension', 'Prolapse of Intestinal Stoma', 'Laryngitis', 'Lymphedema', 'Premature Menopause', 'Testicular Pain', 'Death Neonatal', 'Peripheral Ischemia', 'Gastric Fistula', 'Nail Loss', 'Intraoperative Renal Injury', 'Laryngospasm', 'Osteoporosis', 'Urine Discoloration', 'Leukemia Secondary to Oncology Chemotherapy', 'Gastroesophageal Reflux Disease', 'Hypoglossal Nerve Disorder', 'Vaginal Discharge', 'Gastritis', 'Social Circumstances Other', 'Postnasal Drip', 'Upper Respiratory Infection', 'Colonic Perforation', 'Hematuria', 'Urinary Tract Pain', 'Thrombotic Thrombocytopenic Purpura', 'Wrist Fracture', 'Esophagitis', 'Nasal Congestion', 'Mucositis Oral', 'Stomach Pain', 'Abducens Nerve Disorder', 'Hemoglobinuria', 'Renal Calculi', 'Spinal Fracture', 'Cholecystitis', 'Telangiectasia', 'Vaginal Dryness', 'Wolff-Parkinson-White Syndrome', 'Rectal Fistula', 'Soft Tissue Infection', 'Rectal Necrosis', 'Intraoperative Gastrointestinal Injury', 'Metabolism and Nutrition Disorders Other', 'Soft Tissue Necrosis Lower Limb', 'Irritability', 'Blood Prolactin Abnormal', 'Duodenal Hemorrhage', 'Stroke', 'Hypoalbuminemia', 'Bile Duct Stenosis', 'Arthritis', 'Vaginismus', 'Intraoperative Cardiac Injury', 'Intraoperative Skin Injury', 'Esophageal Obstruction', 'Platelet Count Decreased', 'Sepsis', 'Anal Necrosis', 'Stevens-Johnson Syndrome', 'Nail Ridging', 'Electrocardiogram QT Corrected Interval Prolonged', 'Arteritis Infective', 'Haptoglobin Decreased', 'Testicular Hemorrhage', 'Blood Corticotrophin Decreased', 'Trigeminal Nerve Disorder', 'Vaginal Perforation', 'Peripheral Motor Neuropathy', 'Bladder Infection', 'External Ear Pain', 'Precocious Puberty', 'Hyponatremia', 'Phantom Pain', 'Prolapse of Urostomy', 'Vaginal Fistula', 'Esophageal Varices Hemorrhage', 'Facial Muscle Weakness', 'Malabsorption', 'Intraoperative Endocrine Injury', 'Ileal Hemorrhage', 'Serum Sickness', 'Central Nervous System Necrosis', 'Oral Cavity Fistula', 'Duodenal Ulcer', 'Rectal Stenosis', 'Allergic Reaction', 'Activated Partial Thromboplastin Time Prolonged', 'Constipation', 'Dry Mouth', 'Intraoperative Venous Injury', 'Splenic Infection', 'Pancreatic Fistula', 'Dysarthria', 'Injury to Superior Vena Cava', 'Female Genital Tract Fistula', 'Gallbladder Necrosis', 'Cataract', 'Neck Pain', 'Vital Capacity Abnormal', 'Hypoglycemia', 'Cervicitis Infection', 'Intestinal Stoma Leak', 'Ileal Fistula', 'Lymphocyte Count Increased', 'Urostomy Site Bleeding', 'Weight Loss', 'Ejaculation Disorder', 'Vulval Infection', 'Enterocolitis', 'Lymphocyte Count Decreased', 'Retinoic Acid Syndrome', 'Facial Nerve Disorder', 'Small Intestinal Mucositis', 'Buttock Pain', 'Jejunal Obstruction', 'Accessory Nerve Disorder', 'Delusions', 'Infective Myositis', 'Vaginal Inflammation', 'Disseminated Intravascular Coagulation', 'Myocardial Infarction', 'Burn', 'Malignant and Unspecified (Incl Cysts and Polyps) Other', 'Hepatic Necrosis', 'Uveitis', 'Glossopharyngeal Nerve Disorder', 'Heart Failure', 'Multi-Organ Failure', 'Superior Vena Cava Syndrome', 'Trismus', 'Ileal Obstruction', 'Erythroderma', 'Libido Increased', 'Jejunal Perforation', 'Mobitz Type I', 'Hypertrichosis', 'Gallbladder Fistula', 'Optic Nerve Disorder', 'Hepatic Pain', 'Sinusitis', 'Suicidal Ideation', 'Paronychia', 'Biliary Anastomotic Leak', 'Surgical and Medical Procedures Other', 'Fever', 'Jejunal Ulcer', 'Rash Pustular', 'Myelodysplastic Syndrome', 'Eye Disorders Other', 'Blood and Lymphatic System Disorders Other', 'Uterine Obstruction', 'Atrial Fibrillation', 'Skin Atrophy', 'Lordosis', 'Laryngeal Hemorrhage', 'Periorbital Edema', 'Perineal Pain', 'Unequal Limb Length', 'Edema Limbs', 'Euphoria', 'Growth Accelerated', 'Pruritus', 'Hypertension', 'Soft Tissue Necrosis Upper Limb', 'Myalgia', 'Duodenal Stenosis', 'Sick Sinus Syndrome', 'Ear and Labyrinth Disorders Other', 'Rectal Pain', 'Fallopian Tube Perforation', 'Genital Edema', 'Flushing', 'Peripheral Nerve Infection', 'Intraoperative Ear Injury', 'Fatigue', 'Libido Decreased', 'Lymph Gland Infection', 'Congenital', 'Pelvic Soft Tissue Necrosis', 'Headache', 'Intracranial Hemorrhage', 'Sleep Apnea', 'Tooth Discoloration', 'Gastrointestinal Disorders Other', 'Vasculitis', 'Dysphasia', 'Back Pain', 'Lipohypertrophy', 'Phlebitis', 'Allergic Rhinitis', 'Bruising', 'Dysgeusia', 'Floaters', 'Anal Pain', 'Mucosal Infection', 'Personality Change', 'Vaginal Obstruction', 'Olfactory Nerve Disorder', 'Erectile Dysfunction', 'Myelitis', 'Cardiac Arrest', 'Intraoperative Splenic Injury', 'Urethral Anastomotic Leak', 'Vertigo', 'Dyspareunia', 'Acidosis', 'Exostosis', 'Fibrinogen Decreased', 'Fallopian Tube Anastomotic Leak', 'Capillary Leak Syndrome', 'Duodenal Fistula', 'Rectal Hemorrhage', 'Lymph Node Pain', 'Portal Hypertension', 'Intraoperative Arterial Injury', 'Ventricular Arrhythmia', 'Colonic Stenosis', 'Retroperitoneal Hemorrhage', 'Hearing Impaired', 'Radiculitis', 'Seroma', 'Aphonia', 'Cytokine Release Syndrome', 'Hypersomnia', 'Acoustic Nerve Disorder NOS', 'Nail Infection', 'Hepatic Hemorrhage', 'Nausea', 'Penile Infection', 'Creatinine Increased', 'Hiccups', 'Ureteric Anastomotic Leak', 'Weight Gain', 'Hypothermia', 'Neoplasms Benign', 'Conjunctivitis', 'Blood Antidiuretic Hormone Abnormal', 'Pericardial Tamponade', 'Intraoperative Ocular Injury', 'Prostate Infection', 'Peripheral Sensory Neuropathy', 'Rhinitis Infective', 'Edema Face', 'Non-Cardiac Chest Pain', 'Pharyngitis', 'IVth Nerve Disorder', 'Photosensitivity', 'Uterine Perforation', 'Blurred Vision', 'Lip Pain', 'Adult Respiratory Distress Syndrome', 'Cognitive Disturbance', 'Esophageal Infection', 'Infusion Related Reaction', 'Bronchospasm', 'Appendicitis Perforated', 'Urinary Tract Obstruction', 'Hypoparathyroidism', 'Bronchial Obstruction', 'Peritoneal Infection', 'Transient Ischemic Attacks', 'Vascular Disorders Other', 'Eye Pain', 'Hallucinations', 'Gastric Anastomotic Leak', 'Vitreous Hemorrhage', 'Hepatic Failure', 'Growth Hormone Abnormal', 'Blood Bilirubin Increased', 'Oral Hemorrhage', 'INR Increased', 'Encephalitis Infection', 'Concentration Impairment', 'Hyperuricemia', 'Musculoskeletal Deformity', 'Pancreatic Hemorrhage', 'Anorexia', 'Bone Marrow Hypocellular', 'General Disorders and Administration Site Conditions Other', 'Oligospermia', 'Gastroparesis', 'Jejunal Stenosis', 'Laryngeal Stenosis', 'Sneezing', 'Tracheal Stenosis', 'Bronchopleural Fistula', 'Pericarditis', 'Retinopathy', 'Abdominal Pain', 'Mediastinal Infection', 'Anal Ulcer', 'Skin Ulceration', '']",,FollowUp
+FEV 1 FVC Pre Bronch Percent,FEV 1 FVC Pre Bronch Percent,FEV1FVCPreBronchPercent,Percentage value to represent result of Forced Expiratory Volume in 1 second (FEV1) divided by the Forced Vital Capacity (FVC) pre-bronchodilator.,False,,,,FollowUp
+Menopause Status,Menopause Status,MenopauseStatus,Text term used to describe the patient's menopause status.,False,,"['unknown', 'Not Reported', 'Premenopausal', 'Perimenopausal', 'Postmenopausal', '']",,FollowUp
+CD4 Count,CD4 Count,CD4Count,The text term used to describe the outcome of the procedure to determine the amount of the CD4 expressing cells in a sample.,False,,,,FollowUp
+HAART Treatment Indicator,HAART Treatment Indicator,HAARTTreatmentIndicator,The text term used to indicate whether the patient received Highly Active Antiretroviral Therapy (HAART).,False,,"['Not Reported', 'unknown', 'No', 'Yes', '']",,FollowUp
+Immunosuppressive Treatment Type,Immunosuppressive Treatment Type,ImmunosuppressiveTreatmentType,The text term used to describe the type of immunosuppresive treatment the patient received.,False,,"['Cyclophosphamide', 'unknown', 'None', 'Not Reported', 'Methotrexate', 'Anti-TNFTherapy', 'Other', 'Azathioprine', '']",,FollowUp
+Days to Comorbidity,Days to Comorbidity,DaystoComorbidity,Number of days between the date used for index and the date the patient was diagnosed with a comorbidity.,False,,,,FollowUp
+Hysterectomy Type,Hysterectomy Type,HysterectomyType,The text term used to describe the type of hysterectomy the patient had.,False,,"['unknown', 'Not Reported', 'Radical Hysterectomy', 'Simple Hysterectomy', 'Not performed', 'Hysterectomy NOS', '']",,FollowUp
+FEV1 Ref Post Bronch Percent,FEV1 Ref Post Bronch Percent,FEV1RefPostBronchPercent,The percentage comparison to a normal value reference range of the volume of air that a patient can forcibly exhale from the lungs in one second post-bronchodilator.,False,,,,FollowUp
+Karnofsky Performance Status,Karnofsky Performance Status,KarnofskyPerformanceStatus,Text term used to describe the classification used of the functional capabilities of a person.,False,,"['50', '100', '20', '80', '40', '60', '10', '70', '90', '0', '30', '']",,FollowUp
+CDC HIV Risk Factors,CDC HIV Risk Factors,CDCHIVRiskFactors,"The text term used to describe a risk factor for human immunodeficiency virus, as described by the Center for Disease Control.",False,,"['Homosexual Contact', 'unknown', 'Transfusion Recipient', 'None', 'Not Reported', 'Intravenous Drug User', 'Heterosexual Contact', 'Hemophiliac', '']",,FollowUp
+AIDS Risk Factors,AIDS Risk Factors,AIDSRiskFactors,The text term used to describe a risk factor of the acquired immunodeficiency syndrome (AIDS) that the patient either had at time time of the study or experienced in the past.,False,,"['Candidiasis', 'Coccidioidomycosis', 'Mycobacterium avium Complex', 'Mycobacterium', 'Cryptococcosis', 'Progressive Multifocal Leukoencephalopathy', 'Wasting Syndrome', 'Encephalopathy', 'NOS', 'Herpes Simplex Virus', 'Pneumonia', 'Isosporiasis', 'Mycobacterium tuberculosis', 'Toxoplasmosis', 'Salmonella Septicemia', 'Histoplasmosis', 'Cytomegalovirus', 'Pneumocystis Pneumonia', 'Nocardiosis', '']",,FollowUp
+HTAN Participant ID,HTAN Participant ID,HTANParticipantID,HTAN ID associated with a patient based on HTAN ID SOP (eg HTANx_yyy ),True,,,,FollowUp
+Pregnancy Outcome,Pregnancy Outcome,PregnancyOutcome,The text term used to describe the type of pregnancy the patient had,False,,"['Induced Abortion', 'Ectopic Pregnancy', 'unknown', 'Live Birth', 'Not Reported', 'Stillbirth', 'Miscarriage', '']",,FollowUp
+Body Surface Area,Body Surface Area,BodySurfaceArea,Numeric value used to represent the 2-dimensional extent of the body surface relating height to weight.,False,,,,FollowUp
+HPV Positive Type,HPV Positive Type,HPVPositiveType,Text classification to represent the strain or type of human papillomavirus identified in an individual.,False,,"['52', '26', '58', '68', '35', '82', '31', '16', '53', '66', '39', '18', '56', '70', '45', '73', '63', '59', '33', '51', '']",,FollowUp
+Days to Follow Up,Days to Follow Up,DaystoFollowUp,Number of days between the date used for index and the date of the patient's last follow-up appointment or contact.,True,,,,FollowUp
+Viral Hepatitis Serologies,Viral Hepatitis Serologies,ViralHepatitisSerologies,Text term that describes the kind of serological laboratory test used to determine the patient's hepatitus status.,False,,"['HBV DNA', 'HCV Genotype', 'HBV Genotype', 'unknown', 'Hepatitis C Virus RNA', 'Hepatitis C Antibody', 'Not Reported', 'HBV Core Antibody', 'HBV Surface Antibody', 'Hepatitis B Surface Antigen', '']",,FollowUp
+BMI,BMI,BMI,A calculated numerical quantity that represents an individual's weight to height ratio.,False,,,,FollowUp
+FEV1 Ref Pre Bronch Percent,FEV1 Ref Pre Bronch Percent,FEV1RefPreBronchPercent,The percentage comparison to a normal value reference range of the volume of air that a patient can forcibly exhale from the lungs in one second pre-bronchodilator.,False,,,,FollowUp
+Hepatitis Sustained Virological Response,Hepatitis Sustained Virological Response,HepatitisSustainedVirologicalResponse,The yes/no/unknown indicator used to describe whether the patient received treatment for a risk factor the patient had at the time of or prior to their diagnosis.,False,,"['Not Reported', 'unknown', 'No', 'Yes', '']",,FollowUp
+Diabetes Treatment Type,Diabetes Treatment Type,DiabetesTreatmentType,Text term used to describe the types of treatment used to manage diabetes.,False,,"['Thiazolidinedione', 'Insulin', 'Biguanide', 'Alpha-Glucosidase Inhibitor', 'unknown', 'Sulfonylurea', 'Not Reported', 'Injected Insulin', 'Oral Hypoglycemic', 'Diet', 'Other', '']",,FollowUp
+Hysterectomy Margins Involved,Hysterectomy Margins Involved,HysterectomyMarginsInvolved,The text term used to indicate whether the patient's disease was determined to be involved based on the surgical margins of the hysterectomy.,False,,"['unknown', 'Macroscopic Parametrium', 'None', 'Not Reported', 'Bladder', 'Microscopic Parametrium', 'Vagina', '']",,FollowUp
+DLCO Ref Predictive Percent,DLCO Ref Predictive Percent,DLCORefPredictivePercent,"The value, as a percentage of predicted lung volume, measuring the amount of carbon monoxide detected in a patient's lungs.",False,,,,FollowUp
+Risk Factor,Risk Factor,RiskFactor,The text term used to describe a risk factor the patient had at the time of or prior to their diagnosis.,False,,"['Hemihypertrophy', 'Sarcoidosis', 'Cirrhosis', 'Lymphocytic Thyroiditis', 'Hypospadias', 'Not Reported', 'Tobacco NOS', 'Lynch Syndrome', 'Rheumatoid Arthritis', 'Cholelithiasis', 'Nonalcoholic Fatty Liver Disease', 'Tobacco Smoking', 'Fanconi Anemia', 'Parasitic Disease of Biliary Tract', 'Primary Sclerosing Cholangitis', 'unknown', 'Beckwith-Wiedemann', 'Obesity', 'Low Grade Dysplasia', 'Diabetes NOS', 'Diabetes Type II', 'Human Papillomavirus Infection', 'Allergy Food NOS', 'Common variable immune deficiency (CVID)', 'Chronic Hepatitis', 'Allergy Fruit', 'Alpha-1 Antitrypsin Deficiency', 'Hematologic Disorder NOS', 'Allergy Bee', 'Li-Fraumeni Syndrome', 'Cancer', 'Recurrent Pyogenic Cholangitis', 'Wagr Syndrome', 'Allergy Mold or Dust', 'Hepatitis NOS', 'Iron Overload', 'Thyroid Nodular Hyperplasia', 'Undescended Testis', 'Reflux Disease', 'Allergy Eggs', 'Colon Polyps', 'Headache', 'Epstein-Barr Virus', 'Allergy Animal NOS', 'Autoimmune Atrophic Chronic Gastritis', 'High Grade Dysplasia', 'Diabetes Type I', 'Familial Adenomatous Polyposis', 'Vision Changes', 'Eczema', 'Steatosis', 'Allergy Wasp', 'Diet', 'Alcohol Consumption', 'Allergy Dairy or Lactose', 'Turcot Syndrome', 'Gastric Polyp(s)', 'Allergy Ant', 'Fibrosis', ""Gilbert's Syndrome"", 'Hay Fever', ""Barrett's Esophagus"", 'Serous tubal intraepithelial carcinoma (STIC)', 'Gorlin Syndrome', 'Sensory Changes', 'Allergy Seafood', 'Helicobacter Pylori-Associated Gastritis', 'Myasthenia Gravis', 'Oral Contraceptives', 'Allergy Processed Foods', 'Diverticulitis', 'Tattoo', 'HIV', 'Alcoholic Liver Disease', 'Hepatitis C Infection', 'Allergy Cat', 'Hemochromatosis', ""Behcet's Disease"", 'Hepatic Encephalopathy', 'Denys-Drash Syndrome', 'Pancreatitis', 'Endometriosis', 'Allergy Nuts', 'Allergy Meat', 'Endosalpingiosis', 'Rubinstein-Taybi Syndrome', ""Hashimoto's Thyroiditis"", 'Seizure', 'Nonalcoholic Steatohepatitis', 'Tobacco Smokeless', 'Hepatitis B Infection', 'Allergy Dog', 'Intestinal Metaplasia', '']",,FollowUp
+Recist Targeted Regions Number,Recist Targeted Regions Number,RecistTargetedRegionsNumber,"Numeric value that represents the number of baseline target lesions, as described by the Response Evaluation Criteria in Solid Tumours (RECIST) criteria",False,,,,FollowUp
+Adverse Event Grade,Adverse Event Grade,AdverseEventGrade,"The text term used to describe a specific histone variants, which are proteins that substitute for the core canonical histones.",False,,"['Grade 2', 'Grade 1', 'Grade 5', 'Grade 3', 'Grade 4', '']",,FollowUp
+HIV Viral Load,HIV Viral Load,HIVViralLoad,"Numeric value that represents the concentration of an analyte or aliquot extracted from the sample or sample portion, measured in milligrams per milliliter.",False,,,,FollowUp
+Risk Factor Treatment,Risk Factor Treatment,RiskFactorTreatment,The yes/no/unknown indicator used to describe whether the patient received treatment for a risk factor the patient had at the time of or prior to their diagnosis.,False,,"['Not Reported', 'unknown', 'No', 'Yes', '']",,FollowUp
+ECOG Performance Status,ECOG Performance Status,ECOGPerformanceStatus,The ECOG functional performance status of the patient/participant.,False,,"['5.0', '4.0', '5', '1', '4', '2.0', '2', '0.0', '3.0', '0', '1.0', '3', '']",,FollowUp
+Progression or Recurrence,Progression or Recurrence,ProgressionorRecurrence,Yes/No/unknown indicator to identify whether a patient has had a new tumor event after initial treatment.,True,,"['Yes - Progression or Recurrence', 'Not Reported', 'unknown', 'No']",,FollowUp
+Imaging Result,Imaging Result,ImagingResult,The text term used to describe the result of the imaging or scan performed on the patient.,False,,"['Positive', 'unknown', 'Negative', 'Not Reported', 'Not Performed', 'Indeterminate', '']",,FollowUp
+Hormonal Contraceptive Use,Hormonal Contraceptive Use,HormonalContraceptiveUse,The text term used to indicate whether the patient used hormonal contraceptives.,False,,"['unknown', 'Current User', 'Not Reported', 'Former User', 'Never Used', '']",,FollowUp
+Comorbidity,Comorbidity,Comorbidity,"The text term used to describe a comorbidity disease, which coexists with the patient's malignant disease.",False,,"['Hemihypertrophy', 'Lupus', 'Renal Failure (Requiring Dialysis)', 'GERD', 'Joint Replacement', 'Allergies', 'Bone Fracture(s)', 'Inflammatory Bowel Disease', 'Peptic Ulcer (Ulcer)', 'Cerebrovascular Disease', 'Sarcoidosis', 'Cirrhosis', 'Epilepsy', 'Hyperglycemia', 'Hypospadias', 'Not Reported', 'Lynch Syndrome', 'Rheumatoid Arthritis', 'Myocardial Infarction', 'Cholelithiasis', 'Liver Toxicity (Non-Infectious)', 'Smoking', 'DVT/PE', 'Chronic Renal Failure', 'Fanconi Anemia', 'Acute Renal Failure', 'Bronchitis', 'Organ transplant (site)', 'Primary Sclerosing Cholangitis', 'unknown', 'Tyrosinemia', 'Pulmonary Hemorrhage', 'Biliary Disorder', 'Hepatitis', 'Beckwith-Wiedemann', 'Peutz-Jeghers Disease', 'Deep Vein Thrombosis / Thromboembolism', 'Intraductal Papillary Mucinous Neoplasm', 'MAI', 'Hypothyroidism', 'Obesity', 'Kidney Disease', 'Human Papillomavirus Infection', 'Pulmonary Fibrosis', 'Chronic Hepatitis', 'Peripheral Vascular Disease', 'Renal Insufficiency', 'Coronary Artery Disease', 'Herpes', 'ITP', 'Li-Fraumeni Syndrome', 'Atrial Fibrillation', 'Avascular Necrosis', 'COPD', 'Glycogen Storage Disease', 'Calcium Channel Blockers', 'unknown Etiology', 'Cancer', 'Interstitial Pneumontis or ARDS', 'Wagr Syndrome', 'Cryptogenic Organizing Pneumonia', 'Arrhythmia', 'Hypertension', 'Ulcerative Colitis', 'Alpha-1 Antitrypsin', 'Iron Overload', 'Congestive Heart Failure (CHF)', 'Colon Polyps', 'Headache', 'Epstein-Barr Virus', 'Adenomatous Polyposis Coli', 'Other', 'Anxiety', 'Blood Clots', 'Familial Adenomatous Polyposis', 'Insulin Controlled Diabetes', 'Other Cancer Within 5 Years', 'Pregnancy in Patient or Partner', 'Eczema', 'Steatosis', 'Other Pulmonary Complications', 'Glaucoma', 'Hypercalcemia', 'Adenocarcinoma', 'Rheumatologic Disease', 'Osteoarthritis', 'Connective Tissue Disorder', 'HIV / AIDS', 'Hepatitis A Infection', 'Osteoporosis or Osteopenia', 'Cataracts', 'Gout', 'Turcot Syndrome', 'Liver Cirrhosis (Liver Disease)', 'Diet Controlled Diabetes', 'Dyslipidemia', 'Low Grade Liver Dysplastic Nodule', 'Neuroendocrine Tumor', 'Gastroesophageal Reflux Disease', 'Fibrosis', 'Ischemic Heart Disease', 'Tuberculosis', 'HUS/TTP', 'Diabetic Neuropathy', 'Other Nonmalignant Systemic Disease', 'Pain (Various)', 'Psoriasis', ""Barrett's Esophagus"", 'Gorlin Syndrome', ""Crohn's Disease"", 'Myasthenia Gravis', 'Diverticulitis', 'Diabetes', 'Hepatitis C Infection', 'Hereditary Non-polyposis Colon Cancer', 'Stroke', 'Anemia', ""Behcet's Disease"", 'Asthma', 'Common Variable Immunodeficiency', 'Arthritis', 'Depression', 'Denys-Drash Syndrome', 'Pancreatitis', 'Hyperlipidemia', 'Basal Cell Carcinoma', 'Hypercholesterolemia', 'Heart Disease', 'Peripheral Neuropathy', 'Celiac Disease', 'Rubinstein-Taybi Syndrome', ""Hashimoto's Thyroiditis"", 'Seizure', 'Adrenocortical Insufficiency', 'Type II', 'Gonadal Dysfunction', 'H. pylori Infection', 'Renal Dialysis', 'Nonalcoholic Steatohepatitis', 'Transient Ischemic Attack', 'Hemorrhagic Cystitis', 'High Grade Liver Dysplastic Nodule', 'Hepatitis B Infection', 'Sleep apnea', '']",,FollowUp
+Days to Imaging,Days to Imaging,DaystoImaging,Number of days between the date used for index and the date the imaging or scan was performed on the patient.,False,,,,FollowUp
+Pancreatitis Onset Year,Pancreatitis Onset Year,PancreatitisOnsetYear,TBD,False,,,,FollowUp
+Reflux Treatment Type,Reflux Treatment Type,RefluxTreatmentType,Text term used to describe the types of treatment used to manage gastroesophageal reflux disease (GERD).,False,,"['unknown', 'Not Applicable', 'Antacids', 'No Treatment', 'Medically Treated', 'Not Reported', 'Surgically Treated', 'Proton Pump Inhibitors', 'H2 Blockers', '']",,FollowUp
+Days to Recurrence,Days to Recurrence,DaystoRecurrence,Number of days between the date used for index and the date the patient's disease recurred.,False,True,,"Progression or Recurrence -is- ""Yes - Progression or Recurrence""",FollowUp
+Days to Progression,Days to Progression,DaystoProgression,Number of days between the date used for index and the date the patient's disease progressed.,False,True,,"Progression or Recurrence -is- ""Yes - Progression or Recurrence""",FollowUp
+Progression or Recurrence Anatomic Site,Progression or Recurrence Anatomic Site,ProgressionorRecurrenceAnatomicSite,The text term used to describe the anatomic site of resection; biopsy; tissue or organ of biospecimen origin; progression or recurrent disease; treatment,False,True,"['Conjunctiva', 'Bone of limb NOS', 'Connective subcutaneous and other soft tissues of head face and neck', 'Intra-abdominal lymph nodes', 'Round ligament', 'Hypopharynx NOS', 'Palate NOS', 'Not Reported', 'Hepatic flexure of colon', 'Connective subcutaneous and other soft tissues of lower limb and hip', 'Temporal lobe', 'Base of tongue NOS', 'Biliary tract NOS', 'Retroperitoneum', 'Peripheral nerves and autonomic nervous system of thorax', 'Middle lobe lung', 'Epididymis', 'Body of stomach', 'Myometrium', 'Overlapping lesions of oropharynx', 'Skin of lower limb and hip', 'Cerebrum', 'Specified parts of peritoneum', 'Exocervix', 'Tonsillar pillar', 'Urethra', 'Ill-defined sites within respiratory system', 'Overlapping lesion of lip', 'Subglottis', 'Overlapping lesion of lung', 'Choroid', 'Soft palate NOS', 'Penis NOS', 'Mucosa of upper lip', 'Upper respiratory tract NOS', 'Mediastinum NOS', 'Fundus uteri', 'Endometrium', 'Extrahepatic bile duct', 'Duodenum', 'Overlapping lesion of eye and adnexa', 'Spinal meninges', 'Anterior wall of bladder', 'Overlapping lesion of nasopharynx', 'Anterior wall of nasopharynx', 'Cheek mucosa', 'Carotid body', 'Overlapping lesion of other and unspecified parts of mouth', 'Gastrointestinal tract NOS', 'Bone NOS', 'Pelvic lymph nodes', 'Overlapping lesion of skin', 'Reticuloendothelial system NOS', 'Lateral wall of oropharynx', 'Intrathoracic lymph nodes', 'Gallbladder', 'Overlapping lesion of floor of mouth', 'Ampulla of Vater', 'Descending colon', 'Upper-outer quadrant of breast', 'Tonsil NOS', 'Glottis', 'Intestinal tract NOS', 'Overlapping lesion of rectum anus and anal canal', 'Thorax NOS', 'Overlapping lesion of tongue', 'Lymph nodes of axilla or arm', 'Thymus', 'Pancreas NOS', 'Ureter', 'Overlapping lesion of brain', 'Occipital lobe', 'Esophagus NOS', 'Laryngeal cartilage', 'Hematopoietic system NOS', 'Anterior 2/3 of tongue NOS', 'External lower lip', 'Overlapping lesion of major salivary glands', 'Head of pancreas', 'Nasopharynx NOS', 'Ethmoid sinus', 'Overlapping lesion of endocrine glands and related structures', 'Overlapping lesion of larynx', 'Male genital organs NOS', 'Thyroid gland', 'Posterior wall of bladder', 'Intrahepatic bile duct', 'Pleura NOS', 'Lower lobe lung', 'Scrotum NOS', 'Hypopharyngeal aspect of aryepiglottic fold', 'Lymph node NOS', 'Skin of scalp and neck', 'Skin of upper limb and shoulder', 'Trigone of bladder', 'Superior wall of nasopharynx', 'Appendix', 'Skin NOS', 'Peripheral nerves and autonomic nervous system of trunk NOS', 'Prostate gland', 'Jejunum', 'Tonsillar fossa', 'Other specified parts of male genital organs', 'Overlapping lesion of peripheral nerves and autonomic nervous system', 'Connective subcutaneous and other soft tissues of upper limb and shoulder', 'Spinal cord', 'Spleen', 'Bladder neck', 'Nipple', 'Overlapping lesion of bones joints and articular cartilage', 'Posterior mediastinum', 'Nervous system NOS', 'Prepuce', 'Peripheral nerves and autonomic nervous system of lower limb and hip', 'Overlapping lesion of bladder', 'Mouth NOS', 'Broad ligament', 'Connective subcutaneous and other soft tissues of abdomen', 'Lip NOS', 'Skin of other and unspecified parts of face', 'Parotid gland', 'Long bones of upper limb scapula and associated joints', 'Placenta', 'Orbit NOS', 'Tongue NOS', 'Cervical esophagus', 'Overlapping lesion of heart mediastinum and pleura', 'Upper limb NOS', 'Pancreatic duct', 'Thoracic esophagus', 'Waldeyer ring', 'Peripheral nerves and autonomic nervous system of head face and neck', 'Cecum', 'Parathyroid gland', 'Eye NOS', 'Heart', 'Gum NOS', 'Meninges NOS', 'Connective subcutaneous and other soft tissues of trunk NOS', 'Glans penis', 'Anterior surface of epiglottis', 'Branchial cleft', 'Lymph nodes of inguinal region or leg', 'Postcricoid region', 'Fundus of stomach', 'Testis NOS', 'Overlapping lesion of ill-defined sites', 'Ureteric orifice', 'Lower-inner quadrant of breast', 'Pelvis NOS', 'Endocervix', 'Sphenoid sinus', 'Spermatic cord', 'Acoustic nerve', 'Cerebellum NOS', 'Upper third of esophagus', 'Upper-inner quadrant of breast', 'Floor of mouth NOS', 'Lower gum', 'Other specified parts of pancreas', 'Cardia NOS', 'Bladder NOS', 'Abdominal esophagus', 'Trachea', 'Lateral wall of bladder', 'Mandible', 'Overlapping lesion of biliary tract', 'Lymph nodes of multiple regions', 'Lung NOS', 'Corpus uteri', 'Overlapping lesion of hypopharynx', 'unknown', 'Other ill-defined sites', 'Upper lobe lung', 'Overlapping lesion of respiratory system and intrathoracic organs', 'Splenic flexure of colon', 'Stomach NOS', 'Blood', 'Frontal sinus', 'Short bones of lower limb and associated joints', 'Overlapping lesion of bones joints and articular cartilage of limbs', 'Small intestine NOS', 'Lymph nodes of head face and neck', 'Major salivary gland NOS', 'Long bones of lower limb and associated joints', 'Mucosa of lower lip', 'Overlapping lesion of tonsil', 'Vulva NOS', 'Clitoris', 'Eyelid', 'Ovary', 'Isthmus uteri', 'Overlapping lesion of retroperitoneum and peritoneum', 'Connective subcutaneous and other soft tissues of pelvis', 'Cervix uteri', 'Accessory sinus NOS', 'Head face or neck NOS', 'Islets of Langerhans', 'Pituitary gland', 'Main bronchus', 'Uterine adnexa', 'Overlapping lesion of stomach', 'Other specified parts of female genital organs', 'unknown primary site', 'Urachus', 'Middle ear', 'Sigmoid colon', 'Dorsal surface of tongue NOS', 'Peripheral nerves and autonomic nervous system of abdomen', 'Paraurethral gland', 'Retina', 'Tail of pancreas', 'Connective subcutaneous and other soft tissues of thorax', 'Lacrimal gland', 'Vallecula', 'Ventral surface of tongue NOS', 'Urinary system NOS', 'Lingual tonsil', 'Lower-outer quadrant of breast', 'Rectosigmoid junction', 'Hard palate', 'Maxillary sinus', 'Overlapping lesion of lip oral cavity and pharynx', 'Uvula', 'Brain stem', 'Labium majus', 'Upper gum', 'Pylorus', 'Overlapping lesion of female genital organs', 'Greater curvature of stomach NOS', 'Nasal cavity', 'Overlapping lesion of accessory sinuses', 'Connective subcutaneous and other soft tissues NOS', 'Cranial nerve NOS', 'Overlapping lesion of brain and central nervous system', 'Undescended testis', 'Overlapping lesion of palate', 'Border of tongue', 'External upper lip', 'Ileum', 'Pyriform sinus', 'Overlapping lesion of vulva', 'Adrenal gland NOS', 'Posterior wall of nasopharynx', 'Aortic body and other paraganglia', 'Medulla of adrenal gland', 'Submandibular gland', 'Commissure of lip', 'Female genital tract NOS', 'Meckel diverticulum', 'Frontal lobe', 'Retromolar area', 'Anus NOS', 'Overlapping lesion of penis', 'Ascending colon', 'Liver', 'Rectum NOS', 'Lower limb NOS', 'Body of pancreas', 'Fallopian tube', 'Overlapping lesion of esophagus', 'Overlapping lesion of connective subcutaneous and other soft tissues', 'Endocrine gland NOS', 'Pineal gland', 'Anterior floor of mouth', 'Overlapping lesion of urinary organs', 'Labium minus', 'Descended testis', 'Overlapping lesion of pancreas', 'Posterior wall of oropharynx', 'Central portion of breast', 'Cerebral meninges', 'External lip NOS', 'Ventricle NOS', 'Vertebral column', 'Cloacogenic zone', 'Uterus NOS', 'Middle third of esophagus', 'Olfactory nerve', 'Body of penis', 'Gastric antrum', 'Parametrium', 'Brain NOS', 'Peritoneum NOS', 'Overlapping lesion of male genital organs', 'Overlapping lesion of digestive system', 'Parietal lobe', 'Breast NOS', 'Lateral floor of mouth', 'Lateral wall of nasopharynx', 'Bones of skull and face and associated joints', 'Skin of trunk', 'Skin of lip NOS', 'Overlapping lesion of breast', 'Peripheral nerves and autonomic nervous system of upper limb and shoulder', 'Craniopharyngeal duct', 'Optic nerve', 'Overlapping lesion of corpus uteri', 'Overlapping lesion of cervix uteri', 'Lesser curvature of stomach NOS', 'Bone marrow', 'Autonomic nervous system NOS', 'Supraglottis', 'Lower third of esophagus', 'Renal pelvis', 'Cortex of adrenal gland', 'Abdomen NOS', 'Kidney NOS', 'Pelvic bones sacrum coccyx and associated joints', 'Posterior wall of hypopharynx', 'Vestibule of mouth', 'Peripheral nerves and autonomic nervous system of pelvis', 'Rib sternum clavicle and associated joints', 'Oropharynx NOS', 'Axillary tail of breast', 'Larynx NOS', 'Short bones of upper limb and associated joints', 'Vagina NOS', 'Dome of bladder', 'Transverse colon', 'Anal canal', 'Cauda equina', 'Ciliary body', 'Colon NOS', 'Mucosa of lip NOS', 'External ear', 'Pharynx NOS', 'Cornea NOS', 'Overlapping lesion of small intestine', 'Anterior mediastinum', 'Sublingual gland', 'Overlapping lesion of colon', '']","Progression or Recurrence -is- ""Yes - Progression or Recurrence""",FollowUp
+Days to Progression Free,Days to Progression Free,DaystoProgressionFree,Number of days between the date used for index and the date the patient's disease was formally confirmed as progression-free.,False,True,,"Progression or Recurrence -is- ""Yes - Progression or Recurrence""",FollowUp
+Progression or Recurrence Type,Progression or Recurrence Type,ProgressionorRecurrenceType,The text term used to describe the type of progressive or recurrent disease or relapsed disease.,False,True,"['unknown', 'Biochemical', 'Local', 'Not Reported', 'Regional', 'Distant', '']","Progression or Recurrence -is- ""Yes - Progression or Recurrence""",FollowUp
+FOVY,FOVY,FOVY,Field  of view Y dimension. Floating point value,False,,,,ImagingLevel2
+SizeT,SizeT,SizeT,Number of time points. Integer >= 1,True,,,,ImagingLevel2
+PhysicalSizeX,PhysicalSizeX,PhysicalSizeX,Physical size (X-dimension) of a pixel. Units are set by PhysicalSizeXUnit. Floating point value > 0.,True,,,,ImagingLevel2
+Immersion,Immersion,Immersion,Immersion medium,False,,"['Water', 'Other', 'Oil', 'Air', '']",,ImagingLevel2
+PhysicalSizeY,PhysicalSizeY,PhysicalSizeY,Physical size (Y-dimension) of a pixel. Units are set by PhysicalSizeYUnit. Floating point value > 0.,True,,,,ImagingLevel2
+SizeY,SizeY,SizeY,Size of image: Y dimension (in pixels). Integer >= 1,True,,,,ImagingLevel2
+Passed QC,Passed QC,PassedQC,Did all channels pass QC (if not add free text Comment),True,,"['No - Channels QC', 'Yes']",,ImagingLevel2
+HTAN Data File ID,HTAN Data File ID,HTANDataFileID,Self-identifier for this data file - HTAN ID of this file HTAN ID SOP (eg HTANx_yyy_zzz),True,,,,ImagingLevel2
+Image ID,Image ID,ImageID,"Unique internal image identifier. eg ""Image:0"". (To be extracted from OME-XML)",True,,,,ImagingLevel2
+Pixels BigEndian,Pixels BigEndian,PixelsBigEndian,Boolean (True/False),True,,"['True', 'False']",,ImagingLevel2
+Protocol Link,Protocol Link,ProtocolLink,"Protocols.io ID or DOI link to a free/open protocol resource describing in detail the assay protocol (e.g. surface markers used in Smart-seq, dissociation duration,  lot/batch numbers for key reagents such as primers, sequencing reagent kits, etc.) or the protocol by which the sample was obtained or generated.",True,,,,ImagingLevel2
+Pyramid,Pyramid,Pyramid,Does data file contain pyramid of images,True,,"['No', 'Yes']",,ImagingLevel2
+Component,Component,Component,"Category of metadata (e.g. Diagnosis, Biospecimen, scRNA-seq Level 1, etc.); provide the same one for all items/rows.",True,,,,ImagingLevel2
+File Format,File Format,fileFormat,"Format of a file (e.g. txt, csv, fastq, bam, etc.)",True,,"['bed broadPeak', 'dup', 'xml', 'fastq', 'gct', 'jpg', 'excel', '7z', 'html', 'Python script', 'csv', 'msf', 'tiff', 'tar', 'cloupe', 'txt', 'bigwig', 'hdf5', 'hic', 'DICOM', 'idat', 'avi', 'sav', 'maf', 'zip', 'bgzip', 'mzML', 'rmd', 'locs', 'mov', 'gzip', 'sqlite', 'bed narrowPeak', 'sif', 'vcf', 'abf', 'sdf', 'OME-TIFF', 'czi', 'am', 'sam', 'powerpoint', 'sra', 'R script', 'seg', 'bedgraph', 'Sentrix descriptor file', 'pzfx', 'idx', 'tagAlign', 'pdf', 'tif', 'hyperlink', 'mtx', 'm', 'fasta', 'bed', 'fig', 'wiggle', 'cell am', 'md', 'cel', 'chp', 'raw', 'mpg', 'bam', 'bcf', 'plink', 'svg', 'json', 'dat', 'ab1', 'gff3', 'svs', 'bai', 'bpm', 'RData', 'flagstat', 'recal', 'png', 'doc', 'bed gappedPeak', 'mex', 'gtf', 'tranches', 'tsv']",,ImagingLevel2
+FOV number,FOV number,FOVnumber,Index of FOV (as it pertains to its sequence order). Integer >= 1,False,,,,ImagingLevel2
+SizeZ,SizeZ,SizeZ,Size of image: Z dimension (in pixels). Integer >= 1,True,,,,ImagingLevel2
+Imaging Assay Type,Imaging Assay Type,ImagingAssayType,Type of imaging assay,True,,"['CyCIF', 'MxIF', 'H&E', 'MERFISH', 'ExSeq', 'GeoMX-DSP', 'IMC', 'MIBI', 'Not Applicable', 'SABER', 'CODEX', 'mIHC', 't-CyCIF', 'IHC']",,ImagingLevel2
+NominalMagnification,NominalMagnification,NominalMagnification,The magnification of the lens as specified by the manufacturer - i.e. '60' is a 60X lens. floating point value > 1(no units),True,,,,ImagingLevel2
+SizeC,SizeC,SizeC,Number of channels. Integer >= 1,True,,,,ImagingLevel2
+HTAN Participant ID,HTAN Participant ID,HTANParticipantID,HTAN ID associated with a patient based on HTAN ID SOP (eg HTANx_yyy ),True,,,,ImagingLevel2
+WorkingDistanceUnit,WorkingDistanceUnit,WorkingDistanceUnit,The units of the working distance. See OME enumeration of allowed values for the UnitsLength attribute -- default: microns (um),True,,"['cm', 'nm', 'µm', 'Å', 'mm']",,ImagingLevel2
+Zstack,Zstack,Zstack,Does data file contain a Z-stack of images,True,,"['No', 'Yes']",,ImagingLevel2
+PixelType,PixelType,PixelType,"Data type for each pixel value. E.g. ""uint16""",True,,"['float', 'uint32', 'int16', 'int32', 'uint8', 'bit', 'double', 'int8', 'uint16']",,ImagingLevel2
+Channel Metadata Filename,Channel Metadata Filename,ChannelMetadataFilename,Full path of uploaded companion CSV file containing channel-level metadata details,True,,,,ImagingLevel2
+HTAN Parent Biospecimen ID,HTAN Parent Biospecimen ID,HTANParentBiospecimenID,HTAN Biospecimen Identifier (eg HTANx_yyy_zzz) indicating the biospecimen(s) from which these files were derived; multiple parent biospecimen should be comma-separated,True,,,,ImagingLevel2
+Workflow Start Datetime,Workflow Start Datetime,WorkflowStartDatetime,A combination of date and time of day in the form [-]CCYY-MM-DDThh:mm:ss[Z|(+|-)hh:mm],False,,,,ImagingLevel2
+Tseries,Tseries,Tseries,Does data file contain a time-series of images,True,,"['No', 'Yes']",,ImagingLevel2
+SizeX,SizeX,SizeX,Size of image: X dimension (in pixels). Integer >= 1,True,,,,ImagingLevel2
+Workflow End Datetime,Workflow End Datetime,WorkflowEndDatetime,A combination of date and time of day in the form [-]CCYY-MM-DDThh:mm:ss[Z|(+|-)hh:mm],False,,,,ImagingLevel2
+Comment,Comment,Comment,Free text field (generally for QC comment),False,,,,ImagingLevel2
+LensNA,LensNA,LensNA,The numerical aperture of the lens. Floating point value > 0.,False,,,,ImagingLevel2
+WorkingDistance,WorkingDistance,WorkingDistance,"The working distance of the lens, expressed as a floating point number. Floating point > 0.",False,,,,ImagingLevel2
+Filename,Filename,filename,Name of a file ,True,,,,ImagingLevel2
+PhysicalSizeZ,PhysicalSizeZ,PhysicalSizeZ,Physical size (Z-dimension) of a pixel. Units are set by PhysicalSizeZUnit. Floating point value > 0.,True,,,,ImagingLevel2
+Objective,Objective,Objective,Objective,False,,,,ImagingLevel2
+Microscope,Microscope,Microscope,"Microscope type (manufacturer, model, etc) used for this experiment",True,,,,ImagingLevel2
+FOVX,FOVX,FOVX,Field of view X dimension. Floating point,False,,,,ImagingLevel2
+Software and Version,Software and Version,SoftwareandVersion,Name of software used to generate expression values. String,True,,,,ImagingLevel2
+PlaneCount,PlaneCount,PlaneCount,"Number of Z-planes (not to be confused with downsampled ""pyramid""). Integer >=1",True,,,,ImagingLevel2
+DimensionOrder,DimensionOrder,DimensionOrder,The order in which the individual planes of data are interleaved.,True,,"['XYCTZ', 'ZYX', 'XYTZC', 'XYZTC', 'XYCZT', 'XYZCT']",,ImagingLevel2
+Frame Averaging,Frame Averaging,FrameAveraging,"Number of frames averaged together (if no averaging, set to 1). Integer >= 1",False,,,,ImagingLevel2
+FOVYUnit,FOVYUnit,FOVYUnit,Field of view Y dimension units. See OME enumeration of allowed values for the UnitsLength attribute -- default: microns (um),False,,"['cm', 'nm', 'µm', 'Å', 'mm', '']",,ImagingLevel2
+PhysicalSizeXUnit,PhysicalSizeXUnit,PhysicalSizeXUnit,The units of the physical size of a pixel. See OME enumeration of allowed values for the UnitsLength attribute -- default: microns (um),False,,"['cm', 'nm', 'µm', 'Å', 'mm', '']",,ImagingLevel2
+PhysicalSizeYUnit,PhysicalSizeYUnit,PhysicalSizeYUnit,The units of the physical size of a pixel. See OME enumeration of allowed values for the UnitsLength attribute -- default: microns (um),False,,"['cm', 'nm', 'µm', 'Å', 'mm', '']",,ImagingLevel2
+PhysicalSizeZUnit,PhysicalSizeZUnit,PhysicalSizeZUnit,TBD,False,,,,ImagingLevel2
+FOVXUnit,FOVXUnit,FOVXUnit,Field of view X dimension units. See OME enumeration of allowed values for the UnitsLength attribute -- default: microns (um),False,,"['cm', 'nm', 'µm', 'Å', 'mm', '']",,ImagingLevel2
+Component,Component,Component,"Category of metadata (e.g. Diagnosis, Biospecimen, scRNA-seq Level 1, etc.); provide the same one for all items/rows.",True,,,,FamilyHistory
+HTAN Participant ID,HTAN Participant ID,HTANParticipantID,HTAN ID associated with a patient based on HTAN ID SOP (eg HTANx_yyy ),True,,,,FamilyHistory
+Relative with Cancer History,Relative with Cancer History,RelativewithCancerHistory,The yes/no/unknown indicator used to describe whether any of the patient's relatives have a history of cancer.,False,,"['Not Reported', 'unknown', 'None', 'Yes - Cancer History Relative', '']",,FamilyHistory
+Relationship Age at Diagnosis,Relationship Age at Diagnosis,RelationshipAgeatDiagnosis,The age (in years) when the patient's relative was first diagnosed.,False,True,,"Relative with Cancer History -is- ""Yes - Cancer History Relative""",FamilyHistory
+Relationship Type,Relationship Type,RelationshipType,The subgroup that describes the state of connectedness between members of the unit of society organized around kinship ties.,False,True,"['Foster Sister', 'Uncle', 'Maternal Uncle', 'Foster Daughter', 'Niece', 'Natural Daughter', 'Son-in-law', 'Stepfather', 'Daughter-in-law', 'Maternal Grandmother', 'Domestic Partner', 'Unrelated', 'Stepdaughter', 'Foster Brother', 'Adopted Daughter', 'Adoptive Brother', 'Paternal Half Sibling', 'Step Sibling', 'Full Sister', 'Maternal Grandfather', 'Not Reported', 'Natural Grandchild', 'Adoptive Father', 'Foster Father', 'Half Brother', 'Maternal Half Sibling', 'Son', 'Natural Grandfather', 'Husband', 'Sibling', 'Grandmother', 'Identical Twin Sister', 'Full Brother', 'Grandparent', 'Maternal Great Uncle', 'Brother-in-law', 'Maternal First Cousin Once Removed', 'Ward', 'Child', 'Natural Child', 'Adoptive Mother', 'Fraternal Twin Sister', 'Mother', 'Fraternal Twin Brother', 'Natural Grandmother', 'Maternal Aunt', 'Female Cousin', 'Identical Twin Brother', 'Identical Twin Sibling', 'Paternal Great Aunt', 'Natural Son', 'Stepbrother', 'Natural Sibling', 'Natural Grandparent', 'Maternal Great Grandparent', 'Stepmother', 'Twin Sibling', 'Father', 'Daughter', 'Natural Parent', 'Maternal Grandparent', 'Granddaughter', 'Niece Second Degree Relative', 'Maternal Half Brother', 'Brother', 'Nephew', 'Legal Guardian', 'First Cousin', 'Natural Sister', 'Paternal Great Grandparent', 'unknown', 'Maternal Half Sister', 'Grandfather', 'Parent', 'Paternal First Cousin Once Removed', 'Maternal First Cousin', 'Paternal Grandmother', 'Paternal Grandfather', 'Step Child', 'First Cousin Once Removed', 'Grandchild', 'Natural Father', 'Paternal Half Sister', 'Paternal First Cousin', 'Fraternal Twin Sibling', 'Paternal Aunt', 'Natural Brother', 'Refused', 'Half Sibling', 'Other', 'Paternal Uncle', 'Adoptive Sister', 'Foster Mother', 'Grandson', 'Father-in-law', 'Grand Niece', 'Sister', 'Wife', 'Foster Son', 'Paternal Grandparent', 'Male Cousin', 'Grand Nephew', 'Stepsister', 'Adopted Son', 'Half Sister', 'Mother-in-law', 'Sister-in-law', 'Maternal Great Aunt', 'Cousin', 'Stepson', 'Spouse', 'Aunt', 'Paternal Half Brother', 'Paternal Great Uncle', 'Great Grandchild', 'Natural Mother', '']","Relative with Cancer History -is- ""Yes - Cancer History Relative""",FamilyHistory
+Relationship Gender,Relationship Gender,RelationshipGender,The text term used to describe the gender of the patient's relative with a history of cancer.,False,True,"['Not Reported', 'unknown', 'female', 'unspecified', 'male', '']","Relative with Cancer History -is- ""Yes - Cancer History Relative""",FamilyHistory
+Relatives with Cancer History Count,Relatives with Cancer History Count,RelativeswithCancerHistoryCount,The number of relatives the patient has with a known history of cancer.,False,True,,"Relative with Cancer History -is- ""Yes - Cancer History Relative""",FamilyHistory
+Relationship Primary Diagnosis,Relationship Primary Diagnosis,RelationshipPrimaryDiagnosis,The text term used to describe the malignant diagnosis of the patient's relative with a history of cancer.,False,True,"['Not Reported', 'CNS Cancer', 'Lymphoma', 'Brain Cancer', 'Rhabdomyosarcoma', 'Glioblastoma', 'Leukemia', 'Uterine Cancer', 'Kaposi Sarcoma', 'Laryngeal Cancer', 'Thyroid Cancer', 'Cancer', 'Head and Neck Cancer', 'Hematologic Cancer', 'Multiple Myeloma', 'Colorectal Cancer', 'Rectal Cancer', 'Esophageal Cancer', 'Lymph Node Cancer', 'Lung Cancer', 'Liver Cancer', 'Ewing Sarcoma', 'Neuroblastoma', 'Prostate Cancer', 'Tongue Cancer', 'Melanoma', 'unknown', 'Gynecologic Cancer', 'Osteosarcoma', 'Bone Cancer', 'Gallbladder Cancer', 'Bile Duct Cancer', 'Kidney Cancer', 'Basal Cell Cancer', 'Testicular Cancer', 'Throat Cancer', 'Wilms Tumor', 'Tonsillar Cancer', 'Sarcoma', 'Skin Cancer', 'Spleen Cancer', 'Cervical Cancer', 'Blood Cancer', 'Chondrosarcoma', 'Mesothelioma', 'Pancreas Cancer', 'Breast Cancer', 'Adrenal Gland Cancer', 'Bladder Cancer', 'Ovarian Cancer', 'Gastric Cancer', '']","Relative with Cancer History -is- ""Yes - Cancer History Relative""",FamilyHistory
+Cutaneous Melanoma Tumor Regression Range,Cutaneous Melanoma Tumor Regression Range,CutaneousMelanomaTumorRegressionRange,Description of the degree to which tumor cells are replaced by lymphocytic inflammation with or without dermal melanophages and fibrosis._Range; the difference between the lowest and highest numerical values.,False,,"['Absent', 'Present involving 75% or more', 'unknown', 'Present involving less than 75%', '']",,MelanomaTier3
+Stop Days from Index,Stop Days from Index,StopDaysfromIndex,"Number of days from the date of birth (index date) to the end date of the event (e.g. exposure to environmental factor, treatment start, etc.). Note: if the event occurs at a single time point, e.g. a diagnosis or a lab test, the values for this column is 'Not Applicable'",False,,,,MelanomaTier3
+History of Chronic UV Exposure,History of Chronic UV Exposure,HistoryofChronicUVExposure,History of chronic UV exposure,False,,"['Outdoor recreational', 'Outdoor occupational', 'None', 'Therapeutic', 'Not Reported', '']",,MelanomaTier3
+History of Tanning Bed Use,History of Tanning Bed Use,HistoryofTanningBedUse,History of tanning bed use of the patient,False,,"['10-50 times', 'Less than 10 times', '50-100 times', 'More than 100 times', 'Never', 'Not Reported', '']",,MelanomaTier3
+History of Blistering Sunburn,History of Blistering Sunburn,HistoryofBlisteringSunburn,Patient has history of blistering sunburn,False,,"['No', 'unknown', 'Not Reported', 'Yes', '']",,MelanomaTier3
+Start Days from Index,Start Days from Index,StartDaysfromIndex,"Number of days from the date of birth (index date) to the date of an event (e.g. exposure to environmental factor, treatment start, etc.). If not applicable please enter 'Not Applicable'",True,,,,MelanomaTier3
+HTAN Participant ID,HTAN Participant ID,HTANParticipantID,HTAN ID associated with a patient based on HTAN ID SOP (eg HTANx_yyy ),True,,,,MelanomaTier3
+Melanoma Biopsy Resection Sites,Melanoma Biopsy Resection Sites,MelanomaBiopsyResectionSites,Biopsy resection sites specific to melanoma (not covered in Tiers 1 and 2),False,,"['Skin of sole', 'Skin of neck', 'Skin of scrotum', 'Skin of penis', 'Skin of other parts of face', 'Skin of vulva', 'Skin of ear', 'Skin of palm', 'Skin of upper limb and shoulder', 'Skin of scalp', 'Skin of abdomen', 'skin of trunk-other', 'Skin of chest', 'Skin NOS', 'Skin of breast', 'Skin of lower limb and hip', 'Skin of nose', 'Skin of eye lid', 'skin other', 'Skin of back', 'Skin of lip', 'Not Reported', '']",,MelanomaTier3
+Cutaneous Melanoma Tumor Infiltrating Lymphocytes,Cutaneous Melanoma Tumor Infiltrating Lymphocytes,CutaneousMelanomaTumorInfiltratingLymphocytes,Description of degree of lymphocytic infiltration surrounding and disrupting tumor cells of the vertical growth phase in a cutaneous melanoma.,False,,"['Absent', 'Brisk', 'Nonbrisk', 'unknown', '']",,MelanomaTier3
+History of Atypical Nevi,History of Atypical Nevi,HistoryofAtypicalNevi,Patient has a history of atypical nevi,False,,"['Yes (less than 50)', 'unknown', 'No', 'Yes (more than 50)', 'Not Reported', '']",,MelanomaTier3
+Melanoma Lesion Size,Melanoma Lesion Size,MelanomaLesionSize,"Diameter of lesion determined on skin examination (pre-bx), in mm",False,,,,MelanomaTier3
+Timepoint Label,Timepoint Label,TimepointLabel,"Label to identify the time point at which the clinical data or biospecimen was obtained (e.g. Baseline, End of Treatment, Overall survival, Final). NO PHI/PII INFORMATION IS ALLOWED.",True,,,,MelanomaTier3
+Fitzpatrick Skin Tone,Fitzpatrick Skin Tone,FitzpatrickSkinTone,The Fitzpatrick classification of skin phototype,False,,"['VI', 'III', 'II', 'I', 'unknown', 'V', 'IV', 'Not Reported', '']",,MelanomaTier3
+Cutaneous Melanoma Additional Findings,Cutaneous Melanoma Additional Findings,CutaneousMelanomaAdditionalFindings,Significant pathologic finding present in addition to the cutaneous melanoma.,False,,"['Other', 'Pagetoid Spread', 'Solar Elastosis', 'Vascular Proliferation', 'unknown', 'Nevus Remnant', 'Not Applicable', 'Fibrosing Regression', 'Nesting Melanoma', 'Actinic Keratosis', '']",,MelanomaTier3
+Melanoma Specimen Clark Level Value,Melanoma Specimen Clark Level Value,MelanomaSpecimenClarkLevelValue,Definition of the Clark level or depth of involvement of a melanoma in the skin or a specimen.,False,,"['III', 'II', 'I', 'unknown', 'No Source Documentation', 'V', 'IV', '']",,MelanomaTier3
+Immediate Family History Melanoma,Immediate Family History Melanoma,ImmediateFamilyHistoryMelanoma,Text that describes the age at which the family member was diagnosed with melanoma skin cancer in relationship to their 50th birthday.,False,,"['Before age 50', 'Not before age 50', 'unknown', '']",,MelanomaTier3
+Component,Component,Component,"Category of metadata (e.g. Diagnosis, Biospecimen, scRNA-seq Level 1, etc.); provide the same one for all items/rows.",True,,,,MelanomaTier3
+Cutaneous Melanoma Ulceration,Cutaneous Melanoma Ulceration,CutaneousMelanomaUlceration,Description of extent of disruption to the surface of the skin caused by the cutaneous melanoma.,False,,"['Absent', 'Present', 'Not Reported', 'unknown', '']",,MelanomaTier3
+Cutaneous Melanoma Surgical Margins,Cutaneous Melanoma Surgical Margins,CutaneousMelanomaSurgicalMargins,Text term to indicate presence of tumor at resection margins,False,,"['Not Reported', 'Negative', 'Positive', 'unknown', '']",,MelanomaTier3
+Breast Carcinoma Surgical Procedure Name,Breast Carcinoma Surgical Procedure Name,BreastCarcinomaSurgicalProcedureName,Text name of a surgical procedure performed for a person with a diagnosis of breast cancer,False,,"['Other', 'Modified radical mastectomy', 'Lumpectomy', 'Surgery not performed', 'Partial mastectomy', 'Simple mastectomy', 'Re-excision', 'Radical mastectomy', 'unknown', '']",,BreastCancerTier3
+Breast Carcinoma HER2 Status,Breast Carcinoma HER2 Status,BreastCarcinomaHER2Status,Text term to signify the result of the medical procedure that involves testing a sample of blood or tissue for HER2 in a participant with breast cancer,False,,"['Amplified', 'Positive', 'Non-amplified', 'Not Performed', 'Negative', 'Indeterminate', 'Equivocal', 'unknown', '']",,BreastCancerTier3
+Breast Quadrant Site,Breast Quadrant Site,BreastQuadrantSite,The breast quadrant or structure from which the breast tissue specimen was removed for microscopic examination.,False,,"['Central', 'Upper outer quadrant', 'Nipple', 'Lower outer quadrant', 'Data not available', 'unknown', 'Lower inner quadrant', 'Upper inner quadrant', '']",,BreastCancerTier3
+Invasive Lobular Breast Carcinoma Histologic Category,Invasive Lobular Breast Carcinoma Histologic Category,InvasiveLobularBreastCarcinomaHistologicCategory,The histologic subtype for an infiltrating lobular carcinoma of the breast.,False,,"['Alveolar type', 'Classical type', 'Pleomorphic type', 'unknown', 'Data not available', '']",,BreastCancerTier3
+Hormone Therapy Breast Cancer Prevention Indicator,Hormone Therapy Breast Cancer Prevention Indicator,HormoneTherapyBreastCancerPreventionIndicator,Did the patient receive hormonal therapy for prevention of breast cancer?,False,,"['Yes', 'unknown', 'No', 'Not Applicable', '']",,BreastCancerTier3
+BIRADS Mammography Breast Density Category,BIRADS Mammography Breast Density Category,BIRADSMammographyBreastDensityCategory,The category that describes the relative amount of different tissues present in the breast on a mammogram based on the updated 2015 edition of the American College of Radiology's Breast Imaging Reporting and Data System (BI-RADS) reporting guidelines.,False,,"['Heterogeneously dense', 'Extremely dense', 'Scattered fibroglandular densities', 'Predominantly fatty', 'unknown', 'Data not available', '']",,BreastCancerTier3
+Component,Component,Component,"Category of metadata (e.g. Diagnosis, Biospecimen, scRNA-seq Level 1, etc.); provide the same one for all items/rows.",True,,,,BreastCancerTier3
+Breast Carcinoma PR Staining Intensity,Breast Carcinoma PR Staining Intensity,BreastCarcinomaPRStainingIntensity,Text term to indicate the PR staining intensity on pathology assessment in a participant with breast cancer,False,,"['Other', 'Strong', 'Weak-Strong', 'Weak', 'unknown', 'Weak-Moderate', 'Moderate', 'Moderate-Strong', '']",,BreastCancerTier3
+Breast Carcinoma ER Staining Intensity,Breast Carcinoma ER Staining Intensity,BreastCarcinomaERStainingIntensity,Text term to indicate the ER staining intensity on pathology assessment in a participant with breast cancer,False,,"['Other', 'Strong', 'Weak-Strong', 'Weak', 'unknown', 'Weak-Moderate', 'Moderate', 'Moderate-Strong', '']",,BreastCancerTier3
+Breast Carcinoma PR Status Percentage Value,Breast Carcinoma PR Status Percentage Value,BreastCarcinomaPRStatusPercentageValue,A numerical quantity measured or assigned or computed which captures the progesterone receptor level measured in a participant with breast cancer,False,,,,BreastCancerTier3
+Multifocal Breast Carcinoma Present Indicator,Multifocal Breast Carcinoma Present Indicator,MultifocalBreastCarcinomaPresentIndicator,A response to indicate if there is breast cancer characterized by the presence of multiple cancerous tumors that originate from the same clone and usually located in the same quadrant of the breast.,False,,"['Yes', 'unknown', 'No', 'Data not available', '']",,BreastCancerTier3
+Stop Days from Index,Stop Days from Index,StopDaysfromIndex,"Number of days from the date of birth (index date) to the end date of the event (e.g. exposure to environmental factor, treatment start, etc.). Note: if the event occurs at a single time point, e.g. a diagnosis or a lab test, the values for this column is 'Not Applicable'",False,,,,BreastCancerTier3
+Start Days from Index,Start Days from Index,StartDaysfromIndex,"Number of days from the date of birth (index date) to the date of an event (e.g. exposure to environmental factor, treatment start, etc.). If not applicable please enter 'Not Applicable'",True,,,,BreastCancerTier3
+Breast Carcinoma Estrogen Receptor Status,Breast Carcinoma Estrogen Receptor Status,BreastCarcinomaEstrogenReceptorStatus,Text term to represent the overall result of Estrogen Receptor (ER) testing in a participant with breast cancer,False,,"['Positive', 'Not Performed', 'Negative', 'Indeterminate', 'Performed but Not Available', 'Borderline', 'Equivocal', 'unknown', '']",,BreastCancerTier3
+Prior Invasive Breast Disease,Prior Invasive Breast Disease,PriorInvasiveBreastDisease,Text term to indicate prior invasive breast condition in the participant,False,,"['LCIS', 'Other', 'Invasive breast cancer (unrelated to the current cancer)', 'DCIS', 'unknown', 'Data not available', '']",,BreastCancerTier3
+HER2 Breast Carcinoma Copy Number Total,HER2 Breast Carcinoma Copy Number Total,HER2BreastCarcinomaCopyNumberTotal,"Result of HER2 Copy Number testing (in a participant with breast cancer), expressed as a range of values.",False,,,,BreastCancerTier3
+Breast Imaging Performed Type,Breast Imaging Performed Type,BreastImagingPerformedType,"The kind of technology or method performed for screening, diagnosis, surgical procedures or therapy that aids in the visualization of the breast(s).",False,,"['Ultrasound', 'Mammogram', 'CT', 'PET/CT', 'MRI', 'Data not available', 'unknown', 'Multiple imaging modalities', '']",,BreastCancerTier3
+Mammaprint Risk Group,Mammaprint Risk Group,MammaprintRiskGroup,Text term that represents the risk group for breast cancer as determined by assessment of the MammaPrint test.,False,,"['Low risk', 'Intermediate risk', 'unknown', 'Data not available', 'High risk', '']",,BreastCancerTier3
+Multicentric Breast Carcinoma Present Indicator,Multicentric Breast Carcinoma Present Indicator,MulticentricBreastCarcinomaPresentIndicator,A response to indicate if there is breast cancer characterized by the presence of multiple cancerous tumors that originate from different clones and usually located in different quadrants of the breast.,False,,"['Yes', 'unknown', 'No', 'Data not available', '']",,BreastCancerTier3
+Breast Carcinoma Histology Category,Breast Carcinoma Histology Category,BreastCarcinomaHistologyCategory,Classification of the type of invasive breast carcinoma diagnosed based on histologic attributes.,False,,"['Other', 'Infiltrating ductal carcinoma', 'Infiltrating lobular carcinoma', 'Invasive mammary carcinoma NOS', 'Invasive mixed ductal and lobular carcinoma', '']",,BreastCancerTier3
+Breast Carcinoma HER2 Centromere17 Copynumber Total,Breast Carcinoma HER2 Centromere17 Copynumber Total,BreastCarcinomaHER2Centromere17CopynumberTotal,Number of Cells Counted for HER2 & Centromere 17 Copy Numbers in a participant with breast cancer,False,,,,BreastCancerTier3
+Breast Carcinoma HER2 Ratio Diagnosis,Breast Carcinoma HER2 Ratio Diagnosis,BreastCarcinomaHER2RatioDiagnosis,HER2 ratio of the participant at diagnosis,False,,,,BreastCancerTier3
+Breast Biopsy Procedure Finding Type,Breast Biopsy Procedure Finding Type,BreastBiopsyProcedureFindingType,Text term to describe the result of the examination of the breast tissue specimen or fluid as related to the presence and nature of disease.,False,,"['LCIS', 'Other', 'Cancer', 'DCIS', 'No cancer', 'Atypical hyperplasia', '']",,BreastCancerTier3
+Breast Cancer Genomic Test Performed,Breast Cancer Genomic Test Performed,BreastCancerGenomicTestPerformed,Text term that represents the name of the genomic test performed for breast cancer.,False,,"['Other', 'Not performed', 'Oncotype', 'MammaPrint', 'unknown', 'Data not available', '']",,BreastCancerTier3
+Breast Carcinoma ER Status Percentage Value,Breast Carcinoma ER Status Percentage Value,BreastCarcinomaERStatusPercentageValue,A numerical quantity measured or assigned or computed which captures the estrogen receptor level measured in a participant with breast cancer,False,,,,BreastCancerTier3
+Breast Carcinoma Centromere 17 Copy Number,Breast Carcinoma Centromere 17 Copy Number,BreastCarcinomaCentromere17CopyNumber,"Result of Centromere 17 testing in a sample or specimen of metastatic breast carcinoma, expressed as a range of values.",False,,,,BreastCancerTier3
+Oncotype Risk Group,Oncotype Risk Group,OncotypeRiskGroup,Text term that represents the risk group for breast cancer as determined by assessment of the Oncotype recurrence score.,False,,"['Low risk', 'Intermediate risk', 'unknown', 'Data not available', 'High risk', '']",,BreastCancerTier3
+Breast Carcinoma Detection Method Type,Breast Carcinoma Detection Method Type,BreastCarcinomaDetectionMethodType,"The means, manner of procedure, or systematic course of actions performed in order to discover or identify breast cancer.",False,,"['Other', 'Screening Mammography', 'Clinical Exam', 'Screening MRI', 'Self exam', 'Nipple Discharge', 'unknown', 'Data not available', '']",,BreastCancerTier3
+Invasive Ductal Breast Carcinoma Histologic Category,Invasive Ductal Breast Carcinoma Histologic Category,InvasiveDuctalBreastCarcinomaHistologicCategory,The histologic subtype for the most common type of invasive breast carcinoma.,False,,"['Invasive tubular carcinoma', 'Invasive cribriform carcinoma', 'Other', 'Classical type', 'Invasive micropapillary carcinoma', 'Invasive papillary carcinoma', 'Tubulolobular carcinoma', 'Mucinous carcinoma', 'Invasive carcinoma-type cannot be determined', 'Medullary carcinoma', 'unknown', 'Data not available', '']",,BreastCancerTier3
+Breast Cancer Assessment Tests,Breast Cancer Assessment Tests,BreastCancerAssessmentTests,Text term to identify assessment tests done in participants during diagnosis,False,,"['Other', 'HER2 FISH', 'Progesterone receptor IHC', 'Estrogen receptor IHC', 'HER2 IHC', 'HER2 FISH-CISH', 'unknown', 'Data not available', '']",,BreastCancerTier3
+Timepoint Label,Timepoint Label,TimepointLabel,"Label to identify the time point at which the clinical data or biospecimen was obtained (e.g. Baseline, End of Treatment, Overall survival, Final). NO PHI/PII INFORMATION IS ALLOWED.",True,,,,BreastCancerTier3
+Breast Carcinoma HER2 Chromosome17 Ratio,Breast Carcinoma HER2 Chromosome17 Ratio,BreastCarcinomaHER2Chromosome17Ratio,HER2 chromosome 17 ratio in participants with breast cancer,False,,,,BreastCancerTier3
+HTAN Participant ID,HTAN Participant ID,HTANParticipantID,HTAN ID associated with a patient based on HTAN ID SOP (eg HTANx_yyy ),True,,,,BreastCancerTier3
+Breast Cancer Allred Estrogen Receptor Score,Breast Cancer Allred Estrogen Receptor Score,BreastCancerAllredEstrogenReceptorScore,"The numeric Allred score, that is cell staining percentage plus intensity, to determine estrogen receptor status.",False,,"['2', '7', '5', '6', 'unknown', '4', '8', '3', '1', '0', '10', '']",,BreastCancerTier3
+Oncotype Score,Oncotype Score,OncotypeScore,OncotypeDX recurrence score,False,,,,BreastCancerTier3
+Breast Carcinoma Progesteroner Receptor Status,Breast Carcinoma Progesteroner Receptor Status,BreastCarcinomaProgesteronerReceptorStatus,Text term to represent the overall result of Progresterone Receptor (PR) testing in a participant with breast cancer,False,,"['Positive', 'Not Performed', 'Negative', 'Indeterminate', 'Performed but Not Available', 'Borderline', 'Equivocal', 'unknown', '']",,BreastCancerTier3
+Component,Component,Component,"Category of metadata (e.g. Diagnosis, Biospecimen, scRNA-seq Level 1, etc.); provide the same one for all items/rows.",True,,,,LungCancerTier3
+Current Lung Cancer Symptoms,Current Lung Cancer Symptoms,CurrentLungCancerSymptoms,Reported lung cancer related symptoms person is currently experiencing,False,,"['breath sounds coarse/diminished', 'unknown', 'chest pain or discomfort', 'asbestosis', 'Wheezing', 'shallow inspiration', 'air entry decreased/fair/poor/diminished', 'non-productive cough', 'Not Reported', 'Dyspnea', 'crackles', 'prolonged expiration-long/forced expiratory phase', 'dullness to percussion', 'Dysphagia', 'clear lungs to auscultation or percussion', 'no evidence of lung cancer recurrence', 'rhonci', 'finger clubbing', 'unexplained weight loss', 'patient is NED', 'hoarseness/laryngitis/vocal cord inflammation', 'sinus pain/infection', 'productive cough', 'abnormal breath sounds', 'oxygen supplemental-portable O2 at night or continuous', 'Pneumonia', 'unlabored/normal breathing', 'Other', 'unexplained loss of energy/fatigue', 'cold symptoms/flu/sinus/nasal congestion', 'fair/poor aeration', 'hemoptysis', '']",,LungCancerTier3
+Lung Tumor Location Anatomic Site,Lung Tumor Location Anatomic Site,LungTumorLocationAnatomicSite,Anatomic location of the tumor inside the lung,False,,"['unknown', 'Left', 'Right', 'Not Reported', 'Main carina', '']",,LungCancerTier3
+Lung Cancer Harboring Genomic Aberrations,Lung Cancer Harboring Genomic Aberrations,LungCancerHarboringGenomicAberrations,Genomic aberrations in participants with lung cancer (specific lung cancer associated gene mutations not covered in Tiers 1 and 2),False,,"['EML4-ALK translocation-variant 4', 'unknown', 'G13R KRAS mutation', 'L861Q EGFR mutation', 'A146T KRAS mutation', 'Exon 19 deletion', 'G12A KRAS mutation', 'D963 splice MET mutation', 'EML4-ALK translocation-variant 3', 'D1010 splice MET mutation', 'Not Reported', 'G12D KRAS mutation', 'D1010N MET mutation', 'Intron 14 mutation', 'K601E BRAF mutation', 'L858R EGFR mutation', 'G12R KRAS mutation', 'V600R BRAF mutation', 'G13A KRAS mutation', 'G13D KRAS mutation', 'Intron 13 mutation', 'Q61L KRAS mutation', 'Exon 20 insertion', 'G12V KRAS mutation', 'Exon 14 mutation', 'Exon 14 deletion', 'G719X EGFR mutation', 'EML4-ALK translocation-variant 5', 'G13C KRAS mutation', 'G12C KRAS mutation', 'Q61H KRAS mutation', 'Other', 'V600K BRAF mutation', 'C797S EGFR mutation', 'V600D BRAF mutation', 'EML4-ALK translocation-variant 1', 'T790M EGFR mutation', 'G12S KRAS mutation', 'V600E BRAF mutation', 'EML4-ALK translocation-variant 2', 'G13V KRAS mutation', '']",,LungCancerTier3
+Lung Tumor Lobe Bronchial Location,Lung Tumor Lobe Bronchial Location,LungTumorLobeBronchialLocation,Anatomic lobe and bronchial location of the tumor inside the lung,False,,"['Stump', 'Bronchus', 'Upper lobe', 'unknown', 'Not Reported', 'Lower lobe', 'Middle lobe', '']",,LungCancerTier3
+Lung Cancer Detection Method Type,Lung Cancer Detection Method Type,LungCancerDetectionMethodType,"The means, manner of procedure, or systematic course of actions performed in order to discover or identify lung cancer",False,,"['Chest X-ray', 'unknown', 'Chest CT', 'Data not available', 'Other', 'Low Dose Computed Tomography (LDCT)', '']",,LungCancerTier3
+Lung Topography,Lung Topography,LungTopography,Lung PCA specific topography (not covered in previous tiers),False,,"['unknown', 'LLL orifice Airway wall between LUL carina and LB6-10 carinae', 'LB6A/C  Carina between the superior and medial subsegments of superior segment LLL', 'RB8/9 - Carina between anterior and lateral segments RLL (Carina between RB8 orifice and RB9 orifice)', 'RB10A/C - Carina between medial and apical subsegments posterior segment RLL', 'LMB-Left mainstem bronchus(airway wall between MC & LUL carina)', 'LB9A/B  Carina between the medial and lateral subsegments of the lateral segment LLL', 'LUDB-Carina between the lingula and upper division left upper lobe', 'RLL orifice Airway wall between RML and RB6-10 carinae', 'LB2A/C  Carina between the apical and medial subsegments of the posterior segment of the left upper lobe', 'LUDB-orifice airway wall between LUDB and LB3(LB1+2 carinae)', 'RB9 orifice Lateral segment right lower lobe(airway wall between RB9 and RB9A/B carinae)', 'LUL orifice Airway wall between LUL and LUDB', 'RB1/3 - Carina between apical and anterior segments RUL (Carina between RB1 orifice and RB3 orifice)', 'RML - Carina between RML orifice and RLL orifice', 'RB7A/B - Carina between medial and lateral subsegments medial basal segment RLL', 'LB6A/B  Carina between the superior and lateral subsegments superior segment LLL', 'LB5A/B  Carina between the medial and lateral subsegments inferior segment lingula', 'RB5A/B - Carina between the medial and lateral subsegments of the medial segment of the right middle lobe', 'Carina NOS (Carina not otherwise specified)', 'RB10 Posterior segment right lower lobe (Carina at RB10 orifice takeoff from RLL orifice)', 'LB4 orifice Superior segment lingula(airway wall between LB4 and LB4A/B carinae)', 'RB1A/B - Carina between medial and lateral subsegments apical segment RUL', 'LB3 orifice Anterior segment left upper lobe(airway wall between LB3 and LB3A/B carinae)', 'LB2A/B  Carina between the apical and lateral subsegments of the posterior segment of the left upper lobe', 'LB1B/C  Carina between the medial and lateral subsegments of the apical segment of the left upper lobe', 'RB4/5 - Carina between the lateral and medial segments right middle lobe (Carina between RB4 orifice and RB5 orifice)', 'LB4A/B  Carina between medial and lateral subsegments superior segment lingula', 'TR -Trachea (airway wall between tracheo-esophageal bifurcation and main carina)', 'RMB-Right mainstem bronchus(airway wall between MC & RUL carina)', 'RB3A/B - Carina between the medial and lateral subsegments of the anterior segment RUL', 'RB10 orifice Airway wall between RB10 and RB10A/B carinae', 'LB1/2  Carina between apical and posterior segment left upper lobe (Carina between LB1 orifice and LB2 orifice)', 'RB2/3 - Carina between anterior and posterior segments RUL (Carina between RB2 orifice and RB3 orifice)', 'RB2A/B - Carina between the medial and lateral subsegments of the posterior segment (RUL)', 'LB6  The superior segment of the left lower lobe (Carina between LB6 orifice and lower portion of LLL orifice)', 'MC-Carina between right and left lungs (main carina)', 'RB1 orifice Apical segment - right upper lobe(airway wall between RB1 and RB1A/B carinae)', 'LB8/9  Carina between the anterior and lateral segments LLL (Carina between LB8 orifice and LB9 orifice)', 'Other', 'LB1+2 orifice  The apico-posterior segment of the left upper lobe (airway wall between LB1+2/3 carina and LB1 or LB2)', 'LB8 orifice Anterior segment left lower lobe(airway wall between LB8 and LB8A/B carinae)', 'LB1+2/3  Carina between the apico-posterior and anterior segments of the left upper lobe (Carina between LB1+2 orifice and LB3 orifice)', 'Bronchus Intermedius Bronchus (airway wall) between right upper and right middle lobes', 'LB10 orifice  Posterior segment left lower lobe(airway wall between LB10 and LB10A/B carinae)', 'LB1A/B  Carina between the lateral and medial subsegments of the apical segment of the LUL', 'RB10B/C - Carina between medial and lateral subsegments posterior segment RLL', 'RB8 orifice Anterior segment right lower lobe(airway wall between RB8 and RB8A/B carinae)', 'LB10A/C  Carina between the apical and medial segments of the posterior segment of the LLL', 'RB6A/C - Carina between apical and medial subsegments superior segment RLL', 'RB6 - Carina of superior segment RLL (Carina between RB6 orifice and lower portion of RLL orifice)', 'LB8A/B  Carina between the medial and lateral subsegments of the anterior segment LLL', 'LB9 orifice Lateral segment left lower lobe(airway wall between LB9 and LB9A/B carinae)', 'Not Reported', 'RML orifice Airway wall between RML and RB4/5', 'RUL Carinae between RUL orifice and bronchus intermedius', 'LB6B/C  Carina between the medial and lateral subsegments of the superior segment LLL', 'Carina between LUDB orifice and lingula orifice', 'RB1/2 - Carina between apical and posterior segments right upper lobe (Carina between RB1 orifice and RB2 orifice)', 'RB3 orifice Anterior segment - right upper lobe(airway wall between RB3 and RB3A/B carinae)', 'RB5 orifice Medial segment right middle lobe (airway wall between RB5 and RB5A/B carinae)', 'LL NOS (Left lung not otherwise specified)', 'RB7 Medial basal segment right lower lobe (Carina at RB7 orifice takeoff from RLL orifice)', 'LB1A/C  Carina between the apical and lateral subsegments of the apical segment left upper lobe', 'LB9/10  Carina between the lateral and posterior segments LLL (Carina between LB9 orifice and LB10 orifice)', 'RUL orifice Airway wall between RUL and RB1/RB2/RB3', 'RB4A/B - Carina between the medial and lateral subsegments of the lateral segment of the right middle lobe', 'RB9A/B - Carina between medial and lateral subsegments lateral segment RLL', 'LB4/5  Carina between superior and inferior segment lingula (Carina between LB4 orifice and LB5 orifice)', 'RB4 orifice Lateral segment right middle lobe (airway wall between RB4 and RB4A/B carinae)', 'LB10A/B  Carina between the apical and lateral subsegments of the posterior segment of the LLL', 'RB7 orifice Airway wall between RB7 and RB7A/B carinae', 'LUL Carina between the LUL orifice and LLL orifice (airways)', 'RB9/10 - Carina between lateral and posterior segments RLL', 'LB10B/C  Carina between the medial and lateral subsegments of the posterior segment of the LLL', 'RB10A/B - Carina between medial and lateral subsegments posterior segment RLL', 'RB6A/B - Carina between apical and lateral subsegments superior segment RLL', 'RB2 orifice Posterior segment - right upper lobe(airway wall between RB2 and RB2A/B carinae)', 'RB6B/C - Carina between medial and lateral subsegments superior segment RLL', 'RB8A/B - Carina between medial and lateral subsegments anterior segment RLL', 'LB3A/B Carina between the apical and lateral subsegments of the anterior segment of the left upper lobe', 'RL NOS (Right lung not otherwise specified)', 'RB6 orifice Airway wall between RB6 and RB6A/B/C carinae', 'LB5 orifice Inferior segment lingula(airway wall between LB5 and LB5A/B carinae)', 'LB2B/C  Carina between the medial and lateral subsegments of the posterior segment left upper lobe', 'LB6 orifice Airway wall between LB6 and LB6A/B carinae', 'Lingula orifice airway wall between LUDB and LB4/5 carinae', '']",,LungCancerTier3
+Start Days from Index,Start Days from Index,StartDaysfromIndex,"Number of days from the date of birth (index date) to the date of an event (e.g. exposure to environmental factor, treatment start, etc.). If not applicable please enter 'Not Applicable'",True,,,,LungCancerTier3
+Lung Adjacent Histology Type,Lung Adjacent Histology Type,LungAdjacentHistologyType,The type of morphologic characteristics observed by microscope in the tissue next to a benign or malignant tissue growth,False,,"['Squamous cell lung carcinoma', 'Lung adenocarcinoma', 'unknown', 'Large cell neuroendocrine carcinoma', 'Sarcomatoid carcinoma', 'Lung adenocarcinoma in situ', 'Thoracic NUT carcinoma', 'Carcinoid tumor and lung atypical carcinoid tumor', 'Small cell lung carcinoma', 'Other', 'Not Reported', 'Lung lymphoepithelioma-like carcinoma', 'Bronchioalveolar carcinoma', 'Adenosquamous carcinoma', 'Lung squamous cell carcinoma in situ', 'Large cell lung carcinoma', '']",,LungCancerTier3
+Timepoint Label,Timepoint Label,TimepointLabel,"Label to identify the time point at which the clinical data or biospecimen was obtained (e.g. Baseline, End of Treatment, Overall survival, Final). NO PHI/PII INFORMATION IS ALLOWED.",True,,,,LungCancerTier3
+Lung Cancer Participant Procedure History,Lung Cancer Participant Procedure History,LungCancerParticipantProcedureHistory,Text name of a surgical or operative procedure used in a natural history protocol of a lung cancer participant.,False,,"['Lung Wedge Resection Right', 'Lobectomy Left', 'Lobectomy Right', 'Lung Wedge Resection Left', 'unknown', 'Pneumonectomy Left', 'Lung Wedge Resection Multiple', 'Endobronchial biopsy', 'Mediastinoscopy', 'Other', 'Not Reported', 'Lobectomy Bilateral', 'Brain resection', 'Pneumonectomy Right', 'VATS Sclerosis', 'Lung Wedge Resection Bilateral', 'Segmentectomy', '']",,LungCancerTier3
+HTAN Participant ID,HTAN Participant ID,HTANParticipantID,HTAN ID associated with a patient based on HTAN ID SOP (eg HTANx_yyy ),True,,,,LungCancerTier3
+Stop Days from Index,Stop Days from Index,StopDaysfromIndex,"Number of days from the date of birth (index date) to the end date of the event (e.g. exposure to environmental factor, treatment start, etc.). Note: if the event occurs at a single time point, e.g. a diagnosis or a lab test, the values for this column is 'Not Applicable'",False,,,,LungCancerTier3
+scRNAseq Workflow Parameters Description,scRNAseq Workflow Parameters Description,ScRNAseqWorkflowParametersDescription,"Parameters used to run the workflow. scRNA-seq level 3: e.g. Normalization and log transformation, ran empty drops or doublet detection, used filter on # genes/cell, etc. scRNA-seq Level 4: dimensionality reduction with PCA and 50 components, nearest-neighbor graph with k = 20 and Leiden clustering with resolution = 1, UMAP visualization using 50 PCA components, marker genes used to annotate cell types, information about droplet matrix (all barcodes) to cell matrix (only informative barcodes representing real cells) conversion",True,,,,ScRNA-seqLevel4
+File Format,File Format,fileFormat,"Format of a file (e.g. txt, csv, fastq, bam, etc.)",True,,"['sav', 'svs', 'czi', 'sqlite', 'Python script', 'pdf', 'mex', 'txt', 'bed narrowPeak', 'fastq', 'hyperlink', 'jpg', 'OME-TIFF', 'Sentrix descriptor file', 'msf', 'recal', 'bed', 'html', 'sam', 'hic', 'chp', 'bed gappedPeak', 'tranches', 'm', 'rmd', 'tiff', 'dat', 'locs', 'png', 'tagAlign', 'doc', 'bpm', 'seg', 'bigwig', 'md', 'fasta', 'excel', 'maf', 'idx', 'json', 'mtx', 'mov', 'csv', 'zip', 'abf', 'cell am', 'idat', 'sif', 'flagstat', 'xml', 'raw', 'tar', 'RData', 'plink', 'R script', 'svg', 'bedgraph', '7z', 'gct', 'powerpoint', 'gzip', 'bcf', 'pzfx', 'vcf', 'bgzip', 'gff3', 'dup', 'cloupe', 'tsv', 'sra', 'cel', 'gtf', 'mpg', 'bed broadPeak', 'DICOM', 'sdf', 'wiggle', 'avi', 'bam', 'am', 'fig', 'mzML', 'ab1', 'bai', 'hdf5', 'tif']",,ScRNA-seqLevel4
+Filename,Filename,filename,Name of a file ,True,,,,ScRNA-seqLevel4
+Component,Component,Component,"Category of metadata (e.g. Diagnosis, Biospecimen, scRNA-seq Level 1, etc.); provide the same one for all items/rows.",True,,,,ScRNA-seqLevel4
+HTAN Data File ID,HTAN Data File ID,HTANDataFileID,Self-identifier for this data file - HTAN ID of this file HTAN ID SOP (eg HTANx_yyy_zzz),True,,,,ScRNA-seqLevel4
+Workflow Version,Workflow Version,WorkflowVersion,Major version of the workflow (e.g. Cell Ranger v3.1),True,,,,ScRNA-seqLevel4
+scRNAseq Workflow Type,scRNAseq Workflow Type,ScRNAseqWorkflowType,Generic name for the workflow used to analyze a data set.,True,,"['DEXSeq', 'Differentiation trajectory analysis', 'dropEST', 'HTSeq - FPKM', 'Cell annotation', 'STARsolo', 'Cufflinks', 'Other', 'HCA Optimus', 'CellRanger', 'SEQC']",,ScRNA-seqLevel4
+Workflow Start Datetime,Workflow Start Datetime,WorkflowStartDatetime,A combination of date and time of day in the form [-]CCYY-MM-DDThh:mm:ss[Z|(+|-)hh:mm],False,,,,ScRNA-seqLevel4
+Workflow End Datetime,Workflow End Datetime,WorkflowEndDatetime,A combination of date and time of day in the form [-]CCYY-MM-DDThh:mm:ss[Z|(+|-)hh:mm],False,,,,ScRNA-seqLevel4
+Workflow Link,Workflow Link,WorkflowLink,Link to workflow or command. DockStore.org recommended. URL,True,,,,ScRNA-seqLevel4
+HTAN Parent Data File ID,HTAN Parent Data File ID,HTANParentDataFileID,HTAN Data File Identifier indicating the file(s) from which these files were derived,True,,,,ScRNA-seqLevel4
+Index File Name,Index File Name,IndexFileName,The name (or part of a name) of a file (of any type). String,True,,,,BulkWESLevel2
+Average Insert Size,Average Insert Size,AverageInsertSize,Average insert size collected from samtools. Integer,False,,,,BulkWESLevel2
+Genomic Reference URL,Genomic Reference URL,GenomicReferenceURL,Link to human genome sequence (e.g. ftp://ftp.ebi.ac.uk/pub/databases/gencode/Gencode_human/release_34/GRCh38.primary_assembly.genome.fa.gz) [URL],True,,,,BulkWESLevel2
+Adapter Content,Adapter Content,AdapterContent,State classification given by FASTQC for the metric. Metric specific details about the states are available on their website.,False,,"['unknown', 'PASS', 'FAIL', 'WARN', 'Not Reported', '']",,BulkWESLevel2
+MSI Status,MSI Status,MSIStatus,MSIsensor determination of either microsatellite stability or instability.,False,,"['MSI-high', 'MSI-low', 'MSS', 'MSI', '']",,BulkWESLevel2
+Proportion Targets No Coverage,Proportion Targets No Coverage,ProportionTargetsNoCoverage,Proportion of targets that did not reach 1X coverage over any base from Picard Tools. Number,False,,,,BulkWESLevel2
+Contamination,Contamination,Contamination,Fraction of reads coming from cross-sample contamination collected from GATK4. Number,False,,,,BulkWESLevel2
+Per Sequence Quality Score,Per Sequence Quality Score,PerSequenceQualityScore,State classification given by FASTQC for the metric. Metric specific details about the states are available on their website.,False,,"['unknown', 'PASS', 'FAIL', 'WARN', 'Not Reported', '']",,BulkWESLevel2
+HTAN Data File ID,HTAN Data File ID,HTANDataFileID,Self-identifier for this data file - HTAN ID of this file HTAN ID SOP (eg HTANx_yyy_zzz),True,,,,BulkWESLevel2
+Total Unmapped reads,Total Unmapped reads,TotalUnmappedreads,Number of reads that did not map to genome. Integer,False,,,,BulkWESLevel2
+Per Base Sequence Content,Per Base Sequence Content,PerBaseSequenceContent,State classification given by FASTQC for the metric. Metric specific details about the states are available on their website.,False,,"['unknown', 'PASS', 'FAIL', 'WARN', 'Not Reported', '']",,BulkWESLevel2
+Proportion Reads Mapped,Proportion Reads Mapped,ProportionReadsMapped,Proportion of mapped reads collected from samtools. Number,False,,,,BulkWESLevel2
+Percent GC Content,Percent GC Content,PercentGCContent,The overall %GC of all bases in all sequences. Integer,False,,,,BulkWESLevel2
+Total Uniquely Mapped,Total Uniquely Mapped,TotalUniquelyMapped,Number of reads that map to genome. Integer,False,,,,BulkWESLevel2
+Pairs On Diff CHR,Pairs On Diff CHR,PairsOnDiffCHR,Pairs on different chromosomes collected from samtools. Integer,False,,,,BulkWESLevel2
+Encoding,Encoding,Encoding,Version of ASCII encoding of quality values found in the file. String,False,,,,BulkWESLevel2
+QC Workflow Version,QC Workflow Version,QCWorkflowVersion,Major version for a workflow. String,False,,,,BulkWESLevel2
+Proportion Coverage 30X,Proportion Coverage 30X,ProportionCoverage30X,"Proportion of all reference bases for whole genome sequencing, or targeted bases for whole exome and targeted sequencing, that achieves 30X or greater coverage from Picard Tools.",False,,,,BulkWESLevel2
+QC Workflow Link,QC Workflow Link,QCWorkflowLink,Link to workflow used. String,False,,,,BulkWESLevel2
+HTAN Parent Data File ID,HTAN Parent Data File ID,HTANParentDataFileID,HTAN Data File Identifier indicating the file(s) from which these files were derived,True,,,,BulkWESLevel2
+Sequence Length Distribution,Sequence Length Distribution,SequenceLengthDistribution,State classification given by FASTQC for the metric. Metric specific details about the states are available on their website.,False,,"['unknown', 'PASS', 'FAIL', 'WARN', 'Not Reported', '']",,BulkWESLevel2
+Per Sequence GC Content,Per Sequence GC Content,PerSequenceGCContent,State classification given by FASTQC for the metric. Metric specific details about the states are available on their website.,False,,"['unknown', 'PASS', 'FAIL', 'WARN', 'Not Reported', '']",,BulkWESLevel2
+Alignment Workflow Type,Alignment Workflow Type,AlignmentWorkflowType,Generic name for the workflow used to analyze a data set.,True,,"['BWA-mem', 'BWA with BQSR', 'STAR 2-Pass', 'STAR 2-Pass Transcriptome', 'BWA with Mark Duplicates and BQSR', 'BWA', 'BWA-aln', 'Other Alignment Workflow', 'STAR 2-Pass Genome', 'STAR 2-Pass Chimeric']",,BulkWESLevel2
+Genomic Reference,Genomic Reference,GenomicReference,Exact version of the human genome reference used in the alignment of reads (e.g. https://www.gencodegenes.org/human/),True,,,,BulkWESLevel2
+Per Tile Sequence Quality,Per Tile Sequence Quality,PerTileSequenceQuality,State classification given by FASTQC for the metric. Metric specific details about the states are available on their website.,False,,"['unknown', 'PASS', 'FAIL', 'WARN', 'Not Reported', '']",,BulkWESLevel2
+Average Base Quality,Average Base Quality,AverageBaseQuality,Average base quality collected from samtools. Number,False,,,,BulkWESLevel2
+Average Read Length,Average Read Length,AverageReadLength,Average read length collected from samtools. Integer,False,,,,BulkWESLevel2
+Per Base Sequence Quality,Per Base Sequence Quality,PerBaseSequenceQuality,State classification given by FASTQC for the metric. Metric specific details about the states are available on their website.,False,,"['unknown', 'PASS', 'FAIL', 'WARN', 'Not Reported', '']",,BulkWESLevel2
+Basic Statistics,Basic Statistics,BasicStatistics,State classification given by FASTQC for the metric. Metric specific details about the states are available on their website.,False,,"['unknown', 'PASS', 'FAIL', 'WARN', 'Not Reported', '']",,BulkWESLevel2
+QC Workflow Type,QC Workflow Type,QCWorkflowType,Generic name for the workflow used to analyze a data set. String,False,,,,BulkWESLevel2
+MSI Workflow Link,MSI Workflow Link,MSIWorkflowLink,Link to method workflow (or command) used in estimating the MSI. URL,False,,,,BulkWESLevel2
+MSI Score,MSI Score,MSIScore,Numeric score denoting the aligned reads file's MSI score from MSIsensor. Number,False,,,,BulkWESLevel2
+Proportion Reads Duplicated,Proportion Reads Duplicated,ProportionReadsDuplicated,Proportion of duplicated reads collected from samtools. Number,False,,,,BulkWESLevel2
+Proportion Coverage 10x,Proportion Coverage 10x,ProportionCoverage10x,"Proportion of all reference bases for whole genome sequencing, or targeted bases for whole exome and targeted sequencing, that achieves 10X or greater coverage from Picard Tools.",False,,,,BulkWESLevel2
+Short Reads,Short Reads,ShortReads,Number of reads that were too short. Integer,False,,,,BulkWESLevel2
+File Format,File Format,fileFormat,"Format of a file (e.g. txt, csv, fastq, bam, etc.)",True,,"['avi', 'Python script', 'tar', 'sav', 'bam', 'cel', 'RData', 'zip', 'xml', 'svs', 'bed gappedPeak', 'dat', 'OME-TIFF', 'mzML', 'mpg', 'sra', 'wiggle', 'plink', 'cloupe', 'pzfx', 'fig', 'DICOM', 'doc', 'chp', 'Sentrix descriptor file', 'powerpoint', 'jpg', 'idx', 'gtf', 'bed narrowPeak', 'bcf', 'tif', 'gzip', 'tsv', 'hyperlink', 'm', 'sdf', 'md', '7z', 'csv', 'seg', 'recal', 'tranches', 'bgzip', 'bed', 'tiff', 'mov', 'json', 'fastq', 'maf', 'mex', 'rmd', 'bed broadPeak', 'am', 'sif', 'svg', 'hdf5', 'bai', 'png', 'sqlite', 'tagAlign', 'bpm', 'bedgraph', 'gff3', 'cell am', 'flagstat', 'R script', 'pdf', 'bigwig', 'hic', 'ab1', 'excel', 'txt', 'dup', 'mtx', 'czi', 'vcf', 'sam', 'abf', 'idat', 'raw', 'msf', 'gct', 'html', 'locs', 'fasta']",,BulkWESLevel2
+Total Reads,Total Reads,TotalReads,Total number of reads per sample. Integer,False,,,,BulkWESLevel2
+Sequence Duplication Levels,Sequence Duplication Levels,SequenceDuplicationLevels,State classification given by FASTQC for the metric. Metric specific details about the states are available on their website.,False,,"['unknown', 'PASS', 'FAIL', 'WARN', 'Not Reported', '']",,BulkWESLevel2
+Component,Component,Component,"Category of metadata (e.g. Diagnosis, Biospecimen, scRNA-seq Level 1, etc.); provide the same one for all items/rows.",True,,,,BulkWESLevel2
+Mean Coverage,Mean Coverage,MeanCoverage,"Mean coverage for whole genome sequencing, or mean target coverage for whole exome and targeted sequencing, collected from Picard. Number",False,,,,BulkWESLevel2
+Per Base N Content,Per Base N Content,PerBaseNContent,State classification given by FASTQC for the metric. Metric specific details about the states are available on their website.,False,,"['unknown', 'PASS', 'FAIL', 'WARN', 'Not Reported', '']",,BulkWESLevel2
+Proportion Base Mismatch,Proportion Base Mismatch,ProportionBaseMismatch,Proportion of mismatched bases collected from samtools. Number,False,,,,BulkWESLevel2
+Filename,Filename,filename,Name of a file ,True,,,,BulkWESLevel2
+Contamination Error,Contamination Error,ContaminationError,Estimation error of cross-sample contamination collected from GATK4. Number,False,,,,BulkWESLevel2
+Overrepresented Sequences,Overrepresented Sequences,OverrepresentedSequences,State classification given by FASTQC for the metric. Metric specific details about the states are available on their website.,False,,"['unknown', 'PASS', 'FAIL', 'WARN', 'Not Reported', '']",,BulkWESLevel2
+Custom Alignment Workflow,Custom Alignment Workflow,CustomAlignmentWorkflow,Specify the name of a custom alignment workflow,False,True,,"Alignment Workflow Type -is- ""Other Alignment Workflow""",BulkWESLevel2
+Start Days from Index,Start Days from Index,StartDaysfromIndex,"Number of days from the date of birth (index date) to the date of an event (e.g. exposure to environmental factor, treatment start, etc.). If not applicable please enter 'Not Applicable'",True,,,,SarcomaTier3
+Component,Component,Component,"Category of metadata (e.g. Diagnosis, Biospecimen, scRNA-seq Level 1, etc.); provide the same one for all items/rows.",True,,,,SarcomaTier3
+Sarcoma Subtype,Sarcoma Subtype,SarcomaSubtype,"The subtype related to the scientific determination and investigation, analysis and recognition of the presence and nature of disease, condition, or injury from expressed signs and symptoms of tissue growth resulting from uncontrolled cell proliferation.",False,,"['Liposarcoma', 'Leiomyosarcoma (uterine or extra-uterine)', 'Not Reported', 'Undifferentiated pleomorphic sarcoma', 'undifferentiated pleomorphic sarcoma or malignant fibrous histiosarcoma', 'Gastrointestinal Stromal Tumor', 'Other Synovial Sarcoma Or Malignant Peripheral Nerve Sheath Tumor Sarcoma', 'Other', 'unknown', '']",,SarcomaTier3
+Sarcoma Diagnosis Classification Category,Sarcoma Diagnosis Classification Category,SarcomaDiagnosisClassificationCategory,"High level grouping to describe a diagnostic grouping or category for sarcoma, a malignant mesenchymal cell tumor most commonly arising from muscle, fat, fibrous tissue, bone, cartilage, and blood vessels.",False,,"['Bone Sarcoma', 'Soft Tissue Sarcoma', 'Not Reported', 'Musculoskeletal Sarcoma', 'unknown', '']",,SarcomaTier3
+Sarcoma Tumor Extension Type,Sarcoma Tumor Extension Type,SarcomaTumorExtensionType,The field to indicate the organs and structures to which the tumor has become adherent or has invaded.,False,,"['Intracranial', 'Lymph nodes', 'Parameningeal', 'Not Reported', 'Extraosseous', 'unknown', 'Other', 'Thoracic cavity', '']",,SarcomaTier3
+Timepoint Label,Timepoint Label,TimepointLabel,"Label to identify the time point at which the clinical data or biospecimen was obtained (e.g. Baseline, End of Treatment, Overall survival, Final). NO PHI/PII INFORMATION IS ALLOWED.",True,,,,SarcomaTier3
+Stop Days from Index,Stop Days from Index,StopDaysfromIndex,"Number of days from the date of birth (index date) to the end date of the event (e.g. exposure to environmental factor, treatment start, etc.). Note: if the event occurs at a single time point, e.g. a diagnosis or a lab test, the values for this column is 'Not Applicable'",False,,,,SarcomaTier3
+HTAN Participant ID,HTAN Participant ID,HTANParticipantID,HTAN ID associated with a patient based on HTAN ID SOP (eg HTANx_yyy ),True,,,,SarcomaTier3
+Commit SHA,Commit SHA,CommitSHA,"Short SHA for software version [8 hexadecimal characters (for github), comma separated if multiple]",False,,,,ImagingLevel4
+HTAN Data File ID,HTAN Data File ID,HTANDataFileID,Self-identifier for this data file - HTAN ID of this file HTAN ID SOP (eg HTANx_yyy_zzz),True,,,,ImagingLevel4
+Parameter file,Parameter file,Parameterfile,Filename of a text file listing algorithm version numbers and relevant parameters needed to reproduce the analysis,True,,,,ImagingLevel4
+Component,Component,Component,"Category of metadata (e.g. Diagnosis, Biospecimen, scRNA-seq Level 1, etc.); provide the same one for all items/rows.",True,,,,ImagingLevel4
+File Format,File Format,fileFormat,"Format of a file (e.g. txt, csv, fastq, bam, etc.)",True,,"['powerpoint', 'maf', 'seg', 'bigwig', 'tif', 'gct', 'cell am', 'tsv', '7z', 'DICOM', 'pzfx', 'zip', 'doc', 'sdf', 'tranches', 'wiggle', 'fasta', 'gff3', 'R script', 'chp', 'm', 'tar', 'csv', 'cloupe', 'tagAlign', 'vcf', 'plink', 'idat', 'ab1', 'pdf', 'flagstat', 'sra', 'Sentrix descriptor file', 'bed gappedPeak', 'png', 'cel', 'sif', 'svs', 'sav', 'bam', 'hic', 'sqlite', 'json', 'jpg', 'bgzip', 'fig', 'sam', 'txt', 'html', 'OME-TIFF', 'dat', 'locs', 'abf', 'am', 'msf', 'excel', 'mpg', 'bed', 'xml', 'bpm', 'dup', 'svg', 'gtf', 'gzip', 'hyperlink', 'bed broadPeak', 'fastq', 'bedgraph', 'raw', 'czi', 'bed narrowPeak', 'RData', 'idx', 'mov', 'recal', 'tiff', 'avi', 'md', 'bai', 'mex', 'mtx', 'bcf', 'hdf5', 'rmd', 'Python script', 'mzML']",,ImagingLevel4
+Filename,Filename,filename,Name of a file ,True,,,,ImagingLevel4
+Software and Version,Software and Version,SoftwareandVersion,Name of software used to generate expression values. String,True,,,,ImagingLevel4
+HTAN Parent Biospecimen ID,HTAN Parent Biospecimen ID,HTANParentBiospecimenID,HTAN Biospecimen Identifier (eg HTANx_yyy_zzz) indicating the biospecimen(s) from which these files were derived; multiple parent biospecimen should be comma-separated,True,,,,ImagingLevel4
+HTAN Participant ID,HTAN Participant ID,HTANParticipantID,HTAN ID associated with a patient based on HTAN ID SOP (eg HTANx_yyy ),True,,,,ImagingLevel4
+Colorectal Polyp Shape,Colorectal Polyp Shape,ColorectalPolypShape,Shape of polyp identified in the participant,False,,"['Flat', 'Not stated', 'Sessile', 'Pedunculated', 'Not Applicable', '']",,ColorectalCancerTier3
+Colorectal Cancer KRAS Indicator,Colorectal Cancer KRAS Indicator,ColorectalCancerKRASIndicator,The yes/no/not applicable indicator that describes if patient has diagnosis of colorectal cancer with known KRAS.,False,,"['Yes', 'Not Applicable', 'No', 'unknown', '']",,ColorectalCancerTier3
+Colorectal Polyp Count,Colorectal Polyp Count,ColorectalPolypCount,The total number of polyps detected,False,,,,ColorectalCancerTier3
+Family Medical History Colorectal Polyp Diagnosis,Family Medical History Colorectal Polyp Diagnosis,FamilyMedicalHistoryColorectalPolypDiagnosis,A yes/no/unknown/not applicable indicator related to family medical history diagnosis of polypoid lesion that arises from the colon or rectum and protrudes into the lumen.,False,,"['Yes', 'Not Applicable', 'No', 'unknown', '']",,ColorectalCancerTier3
+Stop Days from Index,Stop Days from Index,StopDaysfromIndex,"Number of days from the date of birth (index date) to the end date of the event (e.g. exposure to environmental factor, treatment start, etc.). Note: if the event occurs at a single time point, e.g. a diagnosis or a lab test, the values for this column is 'Not Applicable'",False,,,,ColorectalCancerTier3
+Timepoint Label,Timepoint Label,TimepointLabel,"Label to identify the time point at which the clinical data or biospecimen was obtained (e.g. Baseline, End of Treatment, Overall survival, Final). NO PHI/PII INFORMATION IS ALLOWED.",True,,,,ColorectalCancerTier3
+Immediate Family History Endometrial Cancer,Immediate Family History Endometrial Cancer,ImmediateFamilyHistoryEndometrialCancer,Text that describes the age at which the family member was diagnosed with endometrial or uterine cancer in relationship to their 50th birthday.,False,,"['Before age 50', 'Not before age 50', 'Not Applicable', 'unknown', '']",,ColorectalCancerTier3
+Patient Colonoscopy Performed Indicator,Patient Colonoscopy Performed Indicator,PatientColonoscopyPerformedIndicator,The yes/no indicator that records if the subject has undergone a previous colonoscopy.,False,,"['Yes', 'Not Applicable', 'No', 'unknown', '']",,ColorectalCancerTier3
+Start Days from Index,Start Days from Index,StartDaysfromIndex,"Number of days from the date of birth (index date) to the date of an event (e.g. exposure to environmental factor, treatment start, etc.). If not applicable please enter 'Not Applicable'",True,,,,ColorectalCancerTier3
+Colorectal Cancer Detection Method Type,Colorectal Cancer Detection Method Type,ColorectalCancerDetectionMethodType,"The means, manner of procedure, or systematic course of actions performed in order to discover or identify colorectal cancer",False,,"['Colonoscopy', 'DNA stool test', 'Fecal occult blood test', 'unknown', 'Virtual colonoscopy', 'Data not available', 'Other', 'Sigmoidoscopy', '']",,ColorectalCancerTier3
+Colorectal Polyp Adenoma Type,Colorectal Polyp Adenoma Type,ColorectalPolypAdenomaType,Type of adenoma associated with the polyp,False,,"['Villous', 'Tubular', 'Not stated', 'Tubulovillous', 'Not Applicable', 'Traditional serrated', 'Sessile serrated', 'Serrated not specified', '']",,ColorectalCancerTier3
+HTAN Participant ID,HTAN Participant ID,HTANParticipantID,HTAN ID associated with a patient based on HTAN ID SOP (eg HTANx_yyy ),True,,,,ColorectalCancerTier3
+Family Colon Cancer History Indicator,Family Colon Cancer History Indicator,FamilyColonCancerHistoryIndicator,The indicator to designate if any first degree relative has a history of colorectal cancer.,False,,"['Yes', 'Not Applicable', 'No', 'unknown', '']",,ColorectalCancerTier3
+Colorectal Polyp Type,Colorectal Polyp Type,ColorectalPolypType,Type of polyp found in the participant,False,,"['Normal', 'unknown', 'Cancer', 'Papillomatous', 'Mixed', 'Other', 'Adenoma', 'Hyperplastic', '']",,ColorectalCancerTier3
+Immediate Family History Ovarian Cancer,Immediate Family History Ovarian Cancer,ImmediateFamilyHistoryOvarianCancer,Text that describes the age at which the family member was diagnosed with ovarian cancer in relationship to their 50th birthday.,False,,"['Before age 50', 'Not before age 50', 'Not Applicable', 'unknown', '']",,ColorectalCancerTier3
+MLH1 Promoter Methylation Status,MLH1 Promoter Methylation Status,MLH1PromoterMethylationStatus,Text term to define the status of promoter methylation for the MLH1 gene. Note: MLH1 gene is commonly associated with hereditary nonpolyposis colorectal cancer. Testing for methylation of the MLH1 promoter can help distinguish sporadic from inherited cancers.,False,,"['Indeterminate', 'Absent', 'Not Assessed', 'Present', '']",,ColorectalCancerTier3
+Component,Component,Component,"Category of metadata (e.g. Diagnosis, Biospecimen, scRNA-seq Level 1, etc.); provide the same one for all items/rows.",True,,,,ColorectalCancerTier3
+Colorectal Cancer Tumor Border Configuration,Colorectal Cancer Tumor Border Configuration,ColorectalCancerTumorBorderConfiguration,The description of the border configuration of a colorectal tumor at pathologic assessment.,False,,"['Infiltrating', 'Indeterminate', 'Pushing', 'Other', 'Not Applicable', '']",,ColorectalCancerTier3
+Size of Polyp Removed,Size of Polyp Removed,SizeofPolypRemoved,Size of the polyp removed in cm,False,,,,ColorectalCancerTier3
+Family History Colorectal Polyp,Family History Colorectal Polyp,FamilyHistoryColorectalPolyp,A yes/no/unknown/not applicable indicator related to family medical history diagnosis of polypoid lesion that arises from the colon or rectum and protrudes into the lumen.,False,,"['Yes', 'Not Applicable', 'No', 'unknown', '']",,ColorectalCancerTier3
+History of Prior Colon Polyps,History of Prior Colon Polyps,HistoryofPriorColonPolyps,Yes/No indicator to describe if the subject had a previous history of colon polyps as noted in the history/physical or previous endoscopic report (s).,False,,"['Yes', 'Not Applicable', 'No', 'unknown', '']",,ColorectalCancerTier3
+Colon Polyp Occurence Indicator,Colon Polyp Occurence Indicator,ColonPolypOccurenceIndicator,Yes/No indicator to describe if the subject had a previous history of colon polyps as noted in the history/physical or previous endoscopic report (s).,False,,"['Yes', 'Not Applicable', 'No', 'unknown', '']",,ColorectalCancerTier3
+Patient Inflammatory Bowel Disease Personal Medica History,Patient Inflammatory Bowel Disease Personal Medica History,PatientInflammatoryBowelDiseasePersonalMedicaHistory,"The indicator for patient's personal medical history of inflammatory bowel disease (chronic, non-specific disorders of unknown etiology, including Crohn disease and ulcerative colitis).",False,,"['No', 'unknown', ""Yes - Crohn's disease"", 'Not Applicable', 'Yes - Ulcerative colitis', '']",,ColorectalCancerTier3
+Colorectal Polyp New Indicator,Colorectal Polyp New Indicator,ColorectalPolypNewIndicator,A yes/no response to a question that asks whether any new polyps greater or equal to two millimeter were identified.,False,,"['Yes', 'Not Applicable', 'No', 'unknown', '']",,ColorectalCancerTier3
diff --git a/js/PrepareRender2.js b/js/PrepareRender2.js
index c7133c8..d9fe470 100644
--- a/js/PrepareRender2.js
+++ b/js/PrepareRender2.js
@@ -47,7 +47,7 @@ function selectDataset() {
         var tangled_tree_data = parseJSON('files/JSON/HTAN_tangled_tree@2.json');
         var normal_dependencies = parseCSVFiles('files/NormalDependencies/normal_dependencies@1.csv');
         var highlight_dependencies = parseCSVFiles('files/HighlighDepedencies/highlight_dependencies@1.csv');
-
+        var merged_data = parseCSVFiles('files/Merged/merged_HTAN.csv');
     }
 
     normal_dependencies.then(data => {
@@ -86,9 +86,15 @@ function selectDataset() {
 
 
                 draw(chart_dta, highlight_data, normal_data);
+
             })
         })
 
+    })
 
+    merged_data.then(data => {
+        drawTable(data, selectedDatasetOption)
     })
+
+
 }
\ No newline at end of file
diff --git a/js/visualization2.js b/js/visualization2.js
index cd44ee7..d76c413 100644
--- a/js/visualization2.js
+++ b/js/visualization2.js
@@ -162,9 +162,6 @@ function chart(data) {
 }
 
 function draw(chart, highlight_data, normal_data) {
-
-    console.log('draw chart function is being used');
-
     const margins = {
         top: 20,
         bottom: 300,
@@ -175,7 +172,7 @@ function draw(chart, highlight_data, normal_data) {
     const color = d3.scaleOrdinal(d3.schemeDark2);
 
     const height = 900;
-    const width = 900;
+    const width = 1000;
 
     const totalWidth = width + margins.left + margins.right;
 
@@ -283,4 +280,64 @@ function draw(chart, highlight_data, normal_data) {
     })
 
 
+}
+
+
+function drawTable(data, selectedDataType) {
+    all_attribute_info = d3.group(data, (d) => d.Component)
+    //see which radio button get selected
+    var rad = document.table.attribute;
+    for (var i = 0; i < rad.length; i++) {
+        rad[i].addEventListener('change', function () {
+            //remove previous graph 
+            d3.select('#table').select('#jsonTable').remove();
+            //create new graph
+            var attribute_to_load = getAttributes(all_attribute_info, selectedDataType, this.value)
+            createTable(attribute_to_load)
+        });
+    }
+
+
+
+}
+
+function getAttributes(all_attribute_info, datatype, radios) {
+    if (radios == "Required Attributes") {
+        var attributes_to_load = all_attribute_info
+            .get(datatype)
+            .filter((d) => d.Required == "True");
+        return attributes_to_load;
+    } else if (radios == "Conditionally Required Attributes") {
+        var attributes_to_load = all_attribute_info
+            .get(datatype)
+            .filter((d) => d.Cond_Req == "True");
+        return attributes_to_load;
+    } else if (radios == "Required and Conditionally Required Attributes") {
+        var attributes_to_load = all_attribute_info
+            .get(datatype)
+            .filter((d) => d.Required === "True" || d.Cond_Req === "True");
+        return attributes_to_load;
+    } else if (radios == "All Attributes") {
+        var attributes_to_load = all_attribute_info.get(datatype);
+        return attributes_to_load;
+    }
+}
+
+
+function createTable(object) {
+    $('#table').append('<table id="jsonTable"><thead><tr></tr></thead><tbody></tbody></table>');
+
+    $.each(Object.keys(object[0]), function (index, key) {
+        $('#jsonTable thead tr').append('<th>' + key + '</th>');
+    });
+    $.each(object, function (index, jsonObject) {
+        if (Object.keys(jsonObject).length > 0) {
+            var tableRow = '<tr>';
+            $.each(Object.keys(jsonObject), function (i, key) {
+                tableRow += '<td>' + jsonObject[key] + '</td>';
+            });
+            tableRow += "</tr>";
+            $('#jsonTable tbody').append(tableRow);
+        }
+    });
 }
\ No newline at end of file
diff --git a/main.html b/main.html
index 799a730..17629be 100644
--- a/main.html
+++ b/main.html
@@ -23,12 +23,37 @@ <h1>Schema visualization</h1>
 
         Choose a dataset type
         <select id="dataset" onchange="selectDataset()"></select>
+
+
+        <div>
+            <form name="table">
+                <label>Please select an option:</label>&nbsp;&nbsp;
+                <input type="radio" name="attribute" id="is_allAttributes" value="All Attributes" , />
+                <label>All Attributes</label>
+
+                <input type="radio" name="attribute" id="is_requiredAttributes" value="Required Attributes" , />
+                <label>Required Attributes</label>
+
+                <input type="radio" name="attribute" id="is_conditionallyRequired"
+                    value="Conditionally Required Attributes" />
+                <label>Conditionally Required Attributes</label>
+
+                <input type="radio" name="attribute" id="is_conditionallyAndRequired"
+                    value="Required and Conditionally Required Attributes" />
+                <label>Required and Conditionally Required Attributes</label>
+            </form>
+        </div>
+
     </div>
 
-    <div id="visualization">
+
+    <div class="center" id="visualization">
 
     </div>
 
+    <div class="center" id="table"></div>
+
+
 
 
 </body>
diff --git a/style3.css b/style3.css
index 5b2e23e..adfc8eb 100644
--- a/style3.css
+++ b/style3.css
@@ -1,19 +1,3 @@
-/* d3 */
-
-/* text {
-    font-family: sans-serif;
-    font-size: 10px;
-  }
-  .node {
-    stroke-linecap: round;
-  }
-  .link {
-    fill: none;
-} */
-
-
-
-
 
 text {
     font-family: sans-serif;
@@ -61,47 +45,26 @@ body h1 {
     padding: 10px;
 }
 
-/* dropdown */
-/* .dropdown_button {
-    background-color: #0979ad;
-    color: white;
-    padding: 16px;
-    font-size: 16px;
-    border: none;
-    cursor: pointer;
-    width: 200px;
-    font-family: montserrat;
-    border: 1px solid #ffffff;
-}
+tr:nth-child(even) td {background: #f2f2f2}
 
-.schema {
-    display: none;
-    position: absolute;
-    background-color: #f1f1f1;
-    min-width: 200px;
-    box-shadow: 0px 8px 16px 0px rgba(0, 0, 0, 0.2);
-    z-index: 1;
+table{
+	border-collapse: collapse;
+  width: 1300px; 
+  height: 400px; 
+  display: block; 
+  overflow-y: scroll; 
+  padding: 10px;
 }
 
-.schema li {
-    color: black;
-    padding: 12px 16px;
-    text-decoration: none;
-    display: block;
-    list-style: none;
-    background-color: white;
-    font-family: montserrat;
-    border: 1px solid white;
+table td, table th{
+	border: 1px solid black;
+  text-align: left; 
 }
-
-.schema li a {
-    text-decoration: none;
-    color: white;
-    display: block;
-    padding: 10px;
+table thead{
+	background:#ccc;
 }
 
-.schema li:hover {
-    background-color: #0979ad;
-    color: white;
-} */
\ No newline at end of file
+.center {
+  display: flex;
+  justify-content: center;
+}
\ No newline at end of file