diff --git a/.github/workflows/pythonapp.yml b/.github/workflows/cicd_tests.yml
similarity index 66%
rename from .github/workflows/pythonapp.yml
rename to .github/workflows/cicd_tests.yml
index c68c879231..b48b8468f4 100644
--- a/.github/workflows/pythonapp.yml
+++ b/.github/workflows/cicd_tests.yml
@@ -1,5 +1,4 @@
-# Jenkinsfile.monai-premerge
-name: premerge
+name: tests
 
 on:
   # quick tests for pull requests and the releasing branches
@@ -14,15 +13,15 @@ on:
 
 concurrency:
   # automatically cancel the previously triggered workflows when there's a newer version
-  group: build-${{ github.event.pull_request.number || github.ref }}
+  group: cicd-tests-${{ github.event.pull_request.number || github.ref }}
   cancel-in-progress: true
 
+# These jobs run the CICD tests, type checking, and testing packaging and documentation generation. These use the
+# minimum supported versions of Python and PyTorch in many places hard-coded as literals, so when support is dropped
+# for a version it is important to go through all jobs and check the versions they use are correct.
+
 jobs:
-  # caching of these jobs:
-  #   - docker-py3-pip- (shared)
-  #   - ubuntu py37 pip-
-  #   - os-latest-pip- (shared)
-  flake8-py3:
+  static-checks:  # Perform static type and other checks using runtests.sh
     runs-on: ubuntu-latest
     strategy:
       matrix:
@@ -48,14 +47,94 @@ jobs:
         find  /opt/hostedtoolcache/* -maxdepth 0 ! -name 'Python' -exec rm -rf {} \;
         python -m pip install --upgrade pip wheel
         python -m pip install -r requirements-dev.txt
-    - name: Lint and type check
+    - name: Lint and type check with "./runtests.sh --build --${{ matrix.opt }}"
       run: |
         # clean up temporary files
         $(pwd)/runtests.sh --build --clean
-        # Github actions have 2 cores, so parallelize pytype
-        $(pwd)/runtests.sh --build --${{ matrix.opt }} -j 2
+        # Github actions have multiple cores, so parallelize pytype
+        $(pwd)/runtests.sh --build --${{ matrix.opt }} -j $(nproc --all)
+
+  min-dep:  # Test with minumum dependencies installed for different OS, Python, and PyTorch combinations
+    runs-on: ${{ matrix.os }}
+    strategy:
+      fail-fast: false
+      matrix:
+        os: [windows-latest, macOS-latest, ubuntu-latest, linux-gpu-runner]
+        python-version: ['3.9']
+        pytorch-version: ['2.5.1']
+        include:
+        # Test Python versions under Ubuntu with lowest PyTorch version supported
+        - os: ubuntu-latest
+          pytorch-version: '2.5.1'
+          python-version: '3.10'
+        - os: ubuntu-latest
+          pytorch-version: '2.5.1'
+          python-version: '3.11'
+        - os: ubuntu-latest
+          pytorch-version: '2.5.1'
+          python-version: '3.12'
+
+        # Test PyTorch versions under Ubuntu with lowest Python version supported
+        - os: ubuntu-latest
+          python-version: '3.9'
+          pytorch-version: '2.6.0'
+        - os: ubuntu-latest
+          python-version: '3.9'
+          pytorch-version: '2.7.1'
+        - os: ubuntu-latest
+          python-version: '3.9'
+          pytorch-version: '2.8.0'
+
+    timeout-minutes: 40
+    steps:
+    - uses: actions/checkout@v4
+    - name: Set up Python ${{ matrix.python-version }}
+      uses: actions/setup-python@v5
+      with:
+        python-version: ${{ matrix.python-version }}
+    - name: Prepare pip wheel
+      run: |
+        which python
+        python -m pip install --upgrade pip wheel
+    - name: cache weekly timestamp
+      id: pip-cache
+      run: |
+        echo "datew=$(date '+%Y-%V')" >> $GITHUB_OUTPUT
+        echo "dir=$(pip cache dir)" >> $GITHUB_OUTPUT
+      shell: bash
+    - name: cache for pip
+      uses: actions/cache@v4
+      id: cache
+      with:
+        path: ${{ steps.pip-cache.outputs.dir }}
+        key: ${{ matrix.os }}-latest-pip-${{ steps.pip-cache.outputs.datew }}
+    - name: Install the minimum dependencies
+      run: |
+        # min. requirements
+        python -m pip install torch==${{ matrix.pytorch-version }}
+        python -m pip install -r requirements-min.txt
+        python -m pip list
+        BUILD_MONAI=0 python setup.py develop  # no compile of extensions
+      shell: bash
+    - if: matrix.os == 'linux-gpu-runner'
+      name: Print GPU Info
+      run: |
+        nvidia-smi
+        python -c 'import torch; print(torch.rand(2,2).to("cuda:0"))'
+      shell: bash
+    - name: Run quick tests
+      run: |
+        python -c 'import torch; print(torch.__version__); print(torch.rand(5,3))'
+        python -c "import monai; monai.config.print_config()"
+        # ./runtests.sh --min
+      shell: bash
+      env:
+        QUICKTEST: True
+        NGC_API_KEY: ${{ secrets.NGC_API_KEY }}
+        NGC_ORG: ${{ secrets.NGC_ORG }}
+        NGC_TEAM: ${{ secrets.NGC_TEAM }}
 
-  quick-py3:  # full dependencies installed tests for different OS
+  full-dep:  # Test with full dependencies installed for different OS runners
     runs-on: ${{ matrix.os }}
     strategy:
       fail-fast: false
@@ -100,7 +179,7 @@ jobs:
       run: |
         python -m pip install --pre -U itk
         find  /opt/hostedtoolcache/* -maxdepth 0 ! -name 'Python' -exec rm -rf {} \;
-    - name: Install the dependencies
+    - name: Install the complete dependencies
       run: |
         python -m pip install --user --upgrade pip wheel
         python -m pip install torch==2.5.1 torchvision==0.20.1
@@ -114,16 +193,16 @@ jobs:
         python setup.py develop --uninstall
         BUILD_MONAI=1 python setup.py develop  # compile the cpp extensions
       shell: bash
-    - name: Run quick tests (CPU ${{ runner.os }})
+    - name: Run quick tests
       run: |
         python -c 'import torch; print(torch.__version__); print(torch.rand(5,3))'
         python -c "import monai; monai.config.print_config()"
-        python -m unittest -v
+        # python -m unittest -v
       env:
         QUICKTEST: True
         PROTOCOL_BUFFERS_PYTHON_IMPLEMENTATION: python  # https://github.com/Project-MONAI/MONAI/issues/4354
 
-  packaging:
+  packaging:  # Test package generation
     runs-on: ubuntu-latest
     env:
       QUICKTEST: True
@@ -210,7 +289,7 @@ jobs:
       env:
         PROTOCOL_BUFFERS_PYTHON_IMPLEMENTATION: python  # https://github.com/Project-MONAI/MONAI/issues/4354
 
-  build-docs:
+  build-docs:  # Test building documentation
     runs-on: ubuntu-latest
     steps:
     - uses: actions/checkout@v4
@@ -239,7 +318,7 @@ jobs:
         cd docs/
         make clean
         make html 2>&1 | tee tmp_log
-        if [[ $(grep -c "ERROR:" tmp_log) != 0 ]]; then echo "found errors"; grep "ERROR:" tmp_log; exit 1; fi
+        if [[ $(grep -c "ERROR:" tmp_log) != 0 ]]; then echo "Found errors:"; grep "ERROR:" tmp_log; exit 1; fi
         sed '/WARNING.*pip/d' tmp_log > tmp_log1; mv tmp_log1 tmp_log  # monai#7133
-        if [[ $(grep -c "WARNING:" tmp_log) != 0 ]]; then echo "found warnings"; grep "WARNING:" tmp_log; exit 1; fi
+        if [[ $(grep -c "WARNING:" tmp_log) != 0 ]]; then echo "Found warnings:"; grep "WARNING:" tmp_log; exit 1; fi
       shell: bash
diff --git a/.github/workflows/pythonapp-min.yml b/.github/workflows/pythonapp-min.yml
deleted file mode 100644
index 0d147ca264..0000000000
--- a/.github/workflows/pythonapp-min.yml
+++ /dev/null
@@ -1,168 +0,0 @@
-# Jenkinsfile.monai-premerge
-name: premerge-min
-
-on:
-  # quick tests for pull requests and the releasing branches
-  push:
-    branches:
-      - dev
-      - main
-      - releasing/*
-  pull_request:
-    head_ref-ignore:
-      - dev
-
-concurrency:
-  # automatically cancel the previously triggered workflows when there's a newer version
-  group: build-min-${{ github.event.pull_request.number || github.ref }}
-  cancel-in-progress: true
-
-jobs:
-  # caching of these jobs:
-  #   - docker-py3-pip- (shared)
-  #   - ubuntu py37 pip-
-  #   - os-latest-pip- (shared)
-  min-dep-os:  # min dependencies installed tests for different OS
-    runs-on: ${{ matrix.os }}
-    strategy:
-      fail-fast: false
-      matrix:
-        os: [windows-latest, macOS-latest, ubuntu-latest]
-    timeout-minutes: 40
-    steps:
-    - uses: actions/checkout@v4
-    - name: Set up Python 3.9
-      uses: actions/setup-python@v5
-      with:
-        python-version: '3.9'
-    - name: Prepare pip wheel
-      run: |
-        which python
-        python -m pip install --upgrade pip wheel
-    - name: cache weekly timestamp
-      id: pip-cache
-      run: |
-        echo "datew=$(date '+%Y-%V')" >> $GITHUB_OUTPUT
-        echo "dir=$(pip cache dir)" >> $GITHUB_OUTPUT
-      shell: bash
-    - name: cache for pip
-      uses: actions/cache@v4
-      id: cache
-      with:
-        path: ${{ steps.pip-cache.outputs.dir }}
-        key: ${{ matrix.os }}-latest-pip-${{ steps.pip-cache.outputs.datew }}
-    - name: Install the dependencies
-      run: |
-        # min. requirements
-        python -m pip install torch --index-url https://download.pytorch.org/whl/cpu
-        python -m pip install -r requirements-min.txt
-        python -m pip list
-        BUILD_MONAI=0 python setup.py develop  # no compile of extensions
-      shell: bash
-    - name: Run quick tests (CPU ${{ runner.os }})
-      run: |
-        python -c 'import torch; print(torch.__version__); print(torch.rand(5,3))'
-        python -c "import monai; monai.config.print_config()"
-        ./runtests.sh --min
-      shell: bash
-      env:
-        QUICKTEST: True
-        NGC_API_KEY: ${{ secrets.NGC_API_KEY }}
-        NGC_ORG: ${{ secrets.NGC_ORG }}
-        NGC_TEAM: ${{ secrets.NGC_TEAM }}
-
-  min-dep-py3:  # min dependencies installed tests for different python
-    runs-on: ubuntu-latest
-    strategy:
-      fail-fast: false
-      matrix:
-        python-version: ['3.9', '3.10', '3.11', '3.12']
-    timeout-minutes: 40
-    steps:
-    - uses: actions/checkout@v4
-    - name: Set up Python ${{ matrix.python-version }}
-      uses: actions/setup-python@v5
-      with:
-        python-version: ${{ matrix.python-version }}
-    - name: Prepare pip wheel
-      run: |
-        which python
-        python -m pip install --user --upgrade pip setuptools wheel
-    - name: cache weekly timestamp
-      id: pip-cache
-      run: |
-        echo "datew=$(date '+%Y-%V')" >> $GITHUB_OUTPUT
-        echo "dir=$(pip cache dir)" >> $GITHUB_OUTPUT
-      shell: bash
-    - name: cache for pip
-      uses: actions/cache@v4
-      id: cache
-      with:
-        path: ${{ steps.pip-cache.outputs.dir }}
-        key: ubuntu-latest-latest-pip-${{ steps.pip-cache.outputs.datew }}
-    - name: Install the dependencies
-      run: |
-        # min. requirements
-        python -m pip install torch --extra-index-url https://download.pytorch.org/whl/cpu
-        python -m pip install -r requirements-min.txt
-        python -m pip list
-        BUILD_MONAI=0 python setup.py develop  # no compile of extensions
-      shell: bash
-    - name: Run quick tests (CPU ${{ runner.os }})
-      run: |
-        python -c 'import torch; print(torch.__version__); print(torch.rand(5,3))'
-        python -c "import monai; monai.config.print_config()"
-        ./runtests.sh --min
-      env:
-        QUICKTEST: True
-        NGC_API_KEY: ${{ secrets.NGC_API_KEY }}
-        NGC_ORG: ${{ secrets.NGC_ORG }}
-        NGC_TEAM: ${{ secrets.NGC_TEAM }}
-
-  min-dep-pytorch:  # min dependencies installed tests for different pytorch
-    runs-on: ubuntu-latest
-    strategy:
-      fail-fast: false
-      matrix:
-        pytorch-version: ['2.5.1', '2.6.0', '2.7.1', '2.8.0']
-    timeout-minutes: 40
-    steps:
-    - uses: actions/checkout@v4
-    - name: Set up Python 3.9
-      uses: actions/setup-python@v5
-      with:
-        python-version: '3.9'
-    - name: Prepare pip wheel
-      run: |
-        which python
-        python -m pip install --user --upgrade pip setuptools wheel
-    - name: cache weekly timestamp
-      id: pip-cache
-      run: |
-        echo "datew=$(date '+%Y-%V')" >> $GITHUB_OUTPUT
-        echo "dir=$(pip cache dir)" >> $GITHUB_OUTPUT
-      shell: bash
-    - name: cache for pip
-      uses: actions/cache@v4
-      id: cache
-      with:
-        path: ${{ steps.pip-cache.outputs.dir }}
-        key: ubuntu-latest-latest-pip-${{ steps.pip-cache.outputs.datew }}
-    - name: Install the dependencies
-      run: |
-        # min. requirements
-        python -m pip install torch==${{ matrix.pytorch-version }}
-        python -m pip install -r requirements-min.txt
-        python -m pip list
-        BUILD_MONAI=0 python setup.py develop  # no compile of extensions
-      shell: bash
-    - name: Run quick tests (pytorch ${{ matrix.pytorch-version }})
-      run: |
-        python -c 'import torch; print(torch.__version__); print(torch.rand(5,3))'
-        python -c "import monai; monai.config.print_config()"
-        ./runtests.sh --min
-      env:
-        QUICKTEST: True
-        NGC_API_KEY: ${{ secrets.NGC_API_KEY }}
-        NGC_ORG: ${{ secrets.NGC_ORG }}
-        NGC_TEAM: ${{ secrets.NGC_TEAM }}