diff --git a/web/libs/datamanager/src/stores/AppStore.js b/web/libs/datamanager/src/stores/AppStore.js
index 78a914305576..352b0e22c9a4 100644
--- a/web/libs/datamanager/src/stores/AppStore.js
+++ b/web/libs/datamanager/src/stores/AppStore.js
@@ -1,6 +1,6 @@
 import { destroy, flow, types } from "mobx-state-tree";
 import { Modal } from "../components/Common/Modal/Modal";
-import { FF_DEV_2887, FF_LOPS_E_3, isFF } from "../utils/feature-flags";
+import { FF_DEV_2887, FF_LOPS_E_3, FF_REGION_VISIBILITY_FROM_URL, isFF } from "../utils/feature-flags";
 import { History } from "../utils/history";
 import { isDefined } from "../utils/utils";
 import { Action } from "./Action";
@@ -199,7 +199,22 @@ export const AppStore = types
 
     setTask: flow(function* ({ taskID, annotationID, pushState }) {
       if (pushState !== false) {
-        History.navigate({ task: taskID, annotation: annotationID ?? null, interaction: null });
+        History.navigate({
+          task: taskID,
+          annotation: annotationID ?? null,
+          interaction: null,
+          region: null,
+        });
+      } else if (isFF(FF_REGION_VISIBILITY_FROM_URL)) {
+        const { task, region, annotation } = History.getParams();
+        History.navigate(
+          {
+            task,
+            region,
+            annotation,
+          },
+          true,
+        );
       }
 
       if (!isDefined(taskID)) return;
@@ -216,20 +231,41 @@ export const AppStore = types
         self.annotationStore.setSelected(annotationID);
       } else {
         self.taskStore.setSelected(taskID);
+      }
 
-        const taskPromise = self.taskStore.loadTask(taskID, {
-          select: !!taskID && !!annotationID,
-        });
+      const taskPromise = self.taskStore.loadTask(taskID, {
+        select: !!taskID && !!annotationID,
+      });
 
-        taskPromise.then(() => {
-          const annotation = self.LSF?.currentAnnotation;
-          const id = annotation?.pk ?? annotation?.id;
+      taskPromise.then(() => {
+        const annotation = self.LSF?.currentAnnotation;
+        const id = annotation?.pk ?? annotation?.id;
 
-          self.LSF?.setLSFTask(self.taskStore.selected, id);
+        self.LSF?.setLSFTask(self.taskStore.selected, id);
 
-          self.setLoadingData(false);
-        });
-      }
+        if (isFF(FF_REGION_VISIBILITY_FROM_URL)) {
+          const { annotation: annIDFromUrl, region: regionIDFromUrl } = History.getParams();
+          if (annIDFromUrl) {
+            const lsfAnnotation = self.LSF.lsf.annotationStore.annotations.find((a) => {
+              return a.pk === annIDFromUrl || a.id === annIDFromUrl;
+            });
+
+            if (lsfAnnotation) {
+              const annID = lsfAnnotation.pk ?? lsfAnnotation.id;
+              self.LSF?.setLSFTask(self.taskStore.selected, annID);
+            }
+          }
+          if (regionIDFromUrl) {
+            const currentAnn = self.LSF?.currentAnnotation;
+            // Focus on the region by hiding all other regions
+            currentAnn?.regionStore?.setRegionVisible(regionIDFromUrl);
+            // Select the region so outliner details are visible
+            currentAnn?.regionStore?.selectRegionByID(regionIDFromUrl);
+          }
+        }
+
+        self.setLoadingData(false);
+      });
     }),
 
     setLoadingData(value) {
@@ -379,7 +415,7 @@ export const AppStore = types
     },
 
     handlePopState: (({ state }) => {
-      const { tab, task, annotation, labeling } = state ?? {};
+      const { tab, task, annotation, labeling, region } = state ?? {};
 
       if (tab) {
         const tabId = Number.parseInt(tab);
@@ -399,6 +435,11 @@ export const AppStore = types
         } else {
           params.id = Number.parseInt(task);
         }
+        if (region) {
+          params.region = region;
+        } else {
+          delete params.region;
+        }
 
         self.startLabeling(params, { pushState: false });
       } else if (labeling) {
diff --git a/web/libs/datamanager/src/utils/feature-flags.js b/web/libs/datamanager/src/utils/feature-flags.js
index 947bfa8ee4e2..d8e2cbf8d00a 100644
--- a/web/libs/datamanager/src/utils/feature-flags.js
+++ b/web/libs/datamanager/src/utils/feature-flags.js
@@ -73,6 +73,11 @@ export const FF_GRID_PREVIEW = "fflag_feat_front_leap_1424_grid_preview_short";
 
 export const FF_MEMORY_LEAK_FIX = "fflag_feat_all_optic_1178_reduce_memory_leak_short";
 
+/**
+ * Add ability to show specific region from URL params (by hiding all other regions).
+ */
+export const FF_REGION_VISIBILITY_FROM_URL = "fflag_feat_front_optic_1553_url_based_region_visibility_short";
+
 // Customize flags
 const flags = {};
 
diff --git a/web/libs/editor/src/stores/RegionStore.js b/web/libs/editor/src/stores/RegionStore.js
index 03b29555e8c7..2dccb7503f87 100644
--- a/web/libs/editor/src/stores/RegionStore.js
+++ b/web/libs/editor/src/stores/RegionStore.js
@@ -507,17 +507,26 @@ export default types
     },
 
     findRegionID(id) {
+      if (!id) return null;
       return self.regions.find((r) => r.id === id);
     },
 
     findRegion(id) {
-      return self.regions.find((r) => r.id === id);
+      return self.findRegionID(id);
     },
 
     filterByParentID(id) {
       return self.regions.filter((r) => r.parentID === id);
     },
 
+    normalizeRegionID(regionId) {
+      if (!regionId) return "";
+      if (!regionId.includes("#")) {
+        regionId = `${regionId}#${self.annotation.id}`;
+      }
+      return regionId;
+    },
+
     afterCreate() {
       onPatch(self, (patch) => {
         if ((patch.op === "add" || patch.op === "delete") && patch.path.indexOf("/regions/") !== -1) {
@@ -582,6 +591,28 @@ export default types
         }
       });
     },
+
+    selectRegionByID(regionId) {
+      const normalizedRegionId = self.normalizeRegionID(regionId);
+      const targetRegion = self.findRegionID(normalizedRegionId);
+      if (!targetRegion) return;
+      self.toggleSelection(targetRegion, true);
+    },
+
+    setRegionVisible(regionId) {
+      const normalizedRegionId = self.normalizeRegionID(regionId);
+      const targetRegion = self.findRegionID(normalizedRegionId);
+      if (!targetRegion) return;
+
+      self.regions.forEach((area) => {
+        if (!area.hidden) {
+          area.toggleHidden();
+        }
+      });
+
+      targetRegion.toggleHidden();
+    },
+
     setHiddenByTool(shouldBeHidden, label) {
       self.regions.forEach((area) => {
         if (area.hidden !== shouldBeHidden && area.type === label.type) {
@@ -589,6 +620,7 @@ export default types
         }
       });
     },
+
     setHiddenByLabel(shouldBeHidden, label) {
       self.regions.forEach((area) => {
         if (area.hidden !== shouldBeHidden) {
@@ -604,6 +636,7 @@ export default types
         }
       });
     },
+
     highlight(area) {
       self.selection.highlight(area);
     },
diff --git a/web/libs/editor/tests/integration/data/outliner/hide-all.ts b/web/libs/editor/tests/integration/data/outliner/hide-all.ts
index e49be0559bb9..055ada26bbec 100644
--- a/web/libs/editor/tests/integration/data/outliner/hide-all.ts
+++ b/web/libs/editor/tests/integration/data/outliner/hide-all.ts
@@ -3,7 +3,7 @@ export const simpleRegionsConfig = `<View>
   <Labels name="label" toName="text">
       <Label value="Label 1"/>
       <Label value="Label 2"/>
-      <Label value="Label 2"/> 
+      <Label value="Label 3"/> 
   </Labels>
 </View>`;
 
diff --git a/web/libs/editor/tests/integration/e2e/outliner/hide-all.cy.ts b/web/libs/editor/tests/integration/e2e/outliner/hide-all.cy.ts
index 062c7b688b84..2f3bda4aed1e 100644
--- a/web/libs/editor/tests/integration/e2e/outliner/hide-all.cy.ts
+++ b/web/libs/editor/tests/integration/e2e/outliner/hide-all.cy.ts
@@ -45,6 +45,97 @@ describe("Outliner - Hide all regions", () => {
     Sidebar.hasHiddenRegion(3);
   });
 
+  it("should hide all regions except the target region by ID from param", () => {
+    LabelStudio.params()
+      .config(simpleRegionsConfig)
+      .data(simpleRegionsData)
+      .withResult(simpleRegionsResult)
+      .withParam("region", "label_2")
+      .init();
+
+    cy.window().then((window: any | unknown) => {
+      window.Htx.annotationStore.annotations[0].regionStore.setRegionVisible(window.LSF_CONFIG.region);
+    });
+
+    Sidebar.hasRegions(3);
+    Sidebar.hasHiddenRegion(2);
+
+    Sidebar.assertRegionHidden(0, "Label 1", true);
+    Sidebar.assertRegionHidden(1, "Label 2", false);
+    Sidebar.assertRegionHidden(2, "Label 3", true);
+  });
+
+  it("should hide all regions except the target region by ID within the targeted annotation tab specified by param", () => {
+    LabelStudio.params()
+      .config(simpleRegionsConfig)
+      .data(simpleRegionsData)
+      .withAnnotation({ id: "10", result: simpleRegionsResult })
+      .withAnnotation({ id: "20", result: simpleRegionsResult })
+      .withParam("annotation", "10")
+      .withParam("region", "label_2")
+      .init();
+
+    cy.window().then((window: any | unknown) => {
+      const annIdFromParam = window.LSF_CONFIG.annotation;
+      const annotations = window.Htx.annotationStore.annotations;
+      const lsfAnnotation = annotations.find((ann: any) => ann.pk === annIdFromParam || ann.id === annIdFromParam);
+      const annID = lsfAnnotation.pk ?? lsfAnnotation.id;
+
+      expect(annID).to.equal("10");
+
+      // Move to the annotation tab specified by param
+      cy.get('[class="lsf-annotations-list__toggle"]').click();
+      cy.get('[class="lsf-annotations-list__entity-id"]').contains("10").click();
+
+      annotations[1].regionStore.setRegionVisible(window.LSF_CONFIG.region);
+    });
+
+    Sidebar.hasRegions(3);
+    Sidebar.hasHiddenRegion(2);
+
+    Sidebar.assertRegionHidden(0, "Label 1", true);
+    Sidebar.assertRegionHidden(1, "Label 2", false);
+    Sidebar.assertRegionHidden(2, "Label 3", true);
+  });
+
+  it("should not hide regions in the non-targeted annotaion tab", () => {
+    LabelStudio.params()
+      .config(simpleRegionsConfig)
+      .data(simpleRegionsData)
+      .withAnnotation({ id: "10", result: simpleRegionsResult })
+      .withAnnotation({ id: "20", result: simpleRegionsResult })
+      .withParam("annotation", "10")
+      .withParam("region", "label_2")
+      .init();
+
+    cy.window().then((window: any | unknown) => {
+      window.Htx.annotationStore.annotations[1].regionStore.setRegionVisible(window.LSF_CONFIG.region);
+    });
+
+    // Validate the annotation tab
+    cy.get('[class="lsf-annotations-list__entity-id"]').should("contain.text", "20");
+
+    Sidebar.hasRegions(3);
+    Sidebar.hasHiddenRegion(0);
+  });
+
+  it("should select the target region by ID from param", () => {
+    LabelStudio.params()
+      .config(simpleRegionsConfig)
+      .data(simpleRegionsData)
+      .withResult(simpleRegionsResult)
+      .withParam("region", "label_2")
+      .init();
+
+    cy.window().then((window: any | unknown) => {
+      window.Htx.annotationStore.annotations[0].regionStore.selectRegionByID(window.LSF_CONFIG.region);
+    });
+
+    Sidebar.hasRegions(3);
+    Sidebar.hasSelectedRegions(1);
+    Sidebar.hasSelectedRegion(1);
+  });
+
   it("should have tooltip for hide action", () => {
     LabelStudio.params().config(simpleRegionsConfig).data(simpleRegionsData).withResult(simpleRegionsResult).init();
 
@@ -61,6 +152,7 @@ describe("Outliner - Hide all regions", () => {
     Sidebar.showAllRegionsButton.trigger("mouseenter");
     Tooltip.hasText("Show all regions");
   });
+
   it("should react to changes in regions' visibility", () => {
     LabelStudio.params().config(simpleRegionsConfig).data(simpleRegionsData).withResult(simpleRegionsResult).init();
 
diff --git a/web/libs/frontend-test/src/helpers/LSF/Sidebar.ts b/web/libs/frontend-test/src/helpers/LSF/Sidebar.ts
index 4d99273dbe9a..e18c7358e5b1 100644
--- a/web/libs/frontend-test/src/helpers/LSF/Sidebar.ts
+++ b/web/libs/frontend-test/src/helpers/LSF/Sidebar.ts
@@ -93,4 +93,8 @@ export const Sidebar = {
   expandDetailsRightPanel() {
     cy.get(".lsf-sidepanels__wrapper_align_right .lsf-panel__header").should("be.visible").click();
   },
+  assertRegionHidden(idx: number, id: string, shouldBeHidden: boolean) {
+    const expectation = shouldBeHidden ? "have.class" : "not.have.class";
+    this.findRegionByIndex(idx).should("contain.text", id).parent().should(expectation, "lsf-tree__node_hidden");
+  },
 };
diff --git a/web/webpack.config.js b/web/webpack.config.js
index 0f1768f888f8..c340a76ff336 100644
--- a/web/webpack.config.js
+++ b/web/webpack.config.js
@@ -264,15 +264,18 @@ module.exports = composePlugins(
                 publicPath: `${FRONTEND_HOSTNAME}/react-app/`,
               },
               allowedHosts: "all", // Allow access from Django's server
-              proxy: [
-                {
-                  context: ["/api"],
-                  target: DJANGO_HOSTNAME,
+              proxy: {
+                "/api": {
+                  target: `${DJANGO_HOSTNAME}/api`,
+                  changeOrigin: true,
+                  pathRewrite: { "^/api": "" },
+                  secure: false,
+                },
+                "/": {
+                  target: `${DJANGO_HOSTNAME}`,
+                  changeOrigin: true,
+                  secure: false,
                 },
-              ],
-              historyApiFallback: {
-                index: "/index.html",
-                disableDotRule: true,
               },
             },
     });