diff --git a/.gitlab/benchmarks/microbenchmarks.yml b/.gitlab/benchmarks/microbenchmarks.yml
index 7e2f105bf65..1e50ef52ada 100644
--- a/.gitlab/benchmarks/microbenchmarks.yml
+++ b/.gitlab/benchmarks/microbenchmarks.yml
@@ -31,7 +31,7 @@ variables:
 
     capture-hardware-software-info.sh
 
-    if [[ $SCENARIO =~ ^flask_* || $SCENARIO =~ ^django_* ]];
+    if [[ $SCENARIO =~ ^flask_* || $SCENARIO =~ ^django_* || $SCENARIO =~ ^startup* ]];
     then
       BP_SCENARIO=$SCENARIO bp-runner "${CI_PROJECT_DIR:-.}/.gitlab/benchmarks/bp-runner.yml" --debug -t
     else
@@ -153,6 +153,7 @@ microbenchmarks:
         - "core_api"
         - "otel_span"
         - "otel_sdk_span"
+        - "startup"
         - "appsec_iast_aspects"
         - "appsec_iast_aspects_ospath"
         - "appsec_iast_aspects_re_module"
@@ -174,9 +175,7 @@ microbenchmarks:
         - "packages_update_imported_dependencies"
         - "recursive_computation"
         - "telemetry_add_metric"
-        # They take a long time to run, and now need the agent running
-        # TODO: Make benchmarks faster, or run less frequently, or as macrobenchmarks
-        # - "startup"
+
 
 benchmarks-pr-comment:
   image: $MICROBENCHMARKS_CI_IMAGE
diff --git a/benchmarks/bm/_scenario.py b/benchmarks/bm/_scenario.py
index 155a9752beb..69bc476b728 100644
--- a/benchmarks/bm/_scenario.py
+++ b/benchmarks/bm/_scenario.py
@@ -25,7 +25,7 @@ def add_cmdline_args(cmd, args):
     cmd = runner.argparser
 
     for _field in dataclasses.fields(scenario_cls):
-        if _field.name == "cprofile_loops":
+        if _field.name in ("cprofile_loops", "inner_loops"):
             continue
 
         cmd.add_argument("--{}".format(_field.name), type=_field.type if _field.type is not bool else str_to_bool)
@@ -50,7 +50,7 @@ def add_cmdline_args(cmd, args):
             finally:
                 pr.dump_stats(pstats_output)
 
-    runner.bench_time_func(scenario.scenario_name, scenario._pyperf)
+    runner.bench_time_func(scenario.scenario_name, scenario._pyperf, inner_loops=scenario._inner_loops)
 
 
 @dataclasses.dataclass
@@ -81,6 +81,18 @@ def _cprofile_loops(self) -> int:
         """
         return getattr(self, "cprofile_loops", 200)
 
+    @property
+    def _inner_loops(self) -> typing.Optional[int]:
+        """Returns the number of inner loops to run for each pyperf iteration.
+
+        This is useful for scenarios that have a very long execution time per operation.
+
+        This can be set in the scenario class as a class variable, "inner_loops", or defaults to None.
+
+        If None, pyperf will determine the number of inner loops automatically.
+        """
+        return getattr(self, "inner_loops", None)
+
     @abc.abstractmethod
     def run(self) -> typing.Generator[typing.Callable[[int], None], None, None]:
         """Returns a context manager that yields a function to be run for performance testing."""
diff --git a/benchmarks/startup/scenario.py b/benchmarks/startup/scenario.py
index f7946590100..8ab19144628 100644
--- a/benchmarks/startup/scenario.py
+++ b/benchmarks/startup/scenario.py
@@ -17,6 +17,9 @@ class Startup(bm.Scenario):
     # Not helpful for subprocess benchmarks
     cprofile_loops: int = 0
 
+    # This benchmark takes a long time to run, reduce the inner loops
+    inner_loops: int = 10
+
     def run(self):
         env = os.environ.copy()
         if self.env: