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Package: escape
Title: Easy single cell analysis platform for enrichment
Version: 2.6.2
Authors@R: c(
person(given = "Nick", family = "Borcherding", role = c("aut", "cre"), email = "ncborch@gmail.com"),
person(given = "Jared", family = "Andrews", role = c("aut"), email = "jared.andrews07@gmail.com"),
person(given = "Tobias", family = "Hoch", role = c("ctb"), email = "tobias@hoch.earth"),
person(given = "Alexei", family = "Martsinkovskiy", role = c("ctb"), email = "alexei.martsinkovskiy@gmail.com")
)
Description: A bridging R package to facilitate gene set enrichment analysis (GSEA) in the context of single-cell RNA sequencing. Using raw count information, Seurat objects, or SingleCellExperiment format, users can perform and visualize ssGSEA, GSVA, AUCell, and UCell-based enrichment calculations across individual cells. Alternatively, escape supports use of rank-based GSEA, such as the use of differential gene expression via fgsea.
License: MIT + file LICENSE
Encoding: UTF-8
LazyData: false
RoxygenNote: 7.3.3
biocViews: Software, SingleCell, Classification, Annotation, GeneSetEnrichment, Sequencing, GeneSignaling, Pathways
Depends: R (>= 4.1)
Imports:
ggdist,
ggplot2 (>= 3.5.0),
grDevices,
Matrix,
MatrixGenerics,
methods,
stats,
SummarizedExperiment,
utils
Suggests:
AUCell,
BiocParallel,
BiocStyle,
DelayedMatrixStats,
dplyr,
fgsea,
GSEABase,
ggraph,
ggridges,
ggpointdensity,
GSVA,
hexbin,
igraph,
irlba,
knitr,
msigdb,
patchwork,
rmarkdown,
rlang,
scran,
SeuratObject,
Seurat,
SingleCellExperiment,
spelling,
stringr,
testthat (>= 3.0.0),
UCell
VignetteBuilder: knitr
Language: en-US
BugReports: https://github.com/BorchLab/escape/issues