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I am interested in using GNomix for local ancestry inference on my phased WES data.
I understand that the pre-trained models used GRCh37 data for training. My data is in GRCh38.
What I'm trying to understand is whether GNomix uses any positional information for the predictions in a way that would make it dependent on a genome build? Is it necessary to retrain the model from scratch using GRCh38 reference in order to use it on my data, or can I use the pre-trained models for my GRCh38 data out of the box? Any advice is highly appreciated.
j-mitra, mojoman666 and 70m43
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